Blood glucose management system for establishing wireless communication connection by combining time and signal intensity

Abstract

The invention discloses a blood glucose management system for establishing wireless communication connection by combining time and signal intensity, a signal intensity threshold value and a time threshold value are preset in the blood glucose management system, timing is carried out during the process that a patient operates to establish the wireless communication connection, and a program module searches for nearby broadcast signals and identifies the signal intensity of the broadcast signals; if the broadcast signal of which the intensity is not less than the preset signal intensity threshold value is searched within the time threshold value, the program module can establish wireless communication connection with the detection module and / or the infusion module which send the broadcast signal without inputting an equipment identifier, otherwise, the program module can establish wireless communication connection with the detection module and / or the infusion module which send the broadcast signal. If the program module does not establish the wireless communication connection with the detection module and / or the infusion module within the time threshold, the patient can input the equipment identifier in the program module to establish the wireless communication connection, so that the reliability of establishing the wireless communication connection between the program module and the detection module and / or the infusion module of the patient is ensured.

Description

Technical Field

[0001] The present invention relates generally to the field of medical devices, and more particularly to a blood glucose management system that combines time and signal strength to establish a wireless communication connection. Background Art

[0002] The pancreas of a normal person can automatically secrete the required insulin / glucagon according to the blood sugar level in the human body, thereby maintaining a reasonable blood sugar fluctuation range. However, the pancreatic function of diabetic patients is abnormal and cannot normally secrete the insulin required by the human body. Diabetes is a metabolic disease and a lifelong disease. Current medical technology cannot cure diabetes, and can only control the occurrence and development of diabetes and its complications by stabilizing blood sugar.

[0003] Diabetic patients need to test their blood sugar before injecting insulin into their bodies. Currently, most detection methods use in-vivo blood sugar detection devices to achieve continuous detection of blood sugar. In-vivo blood sugar detection devices use disposable transcutaneous sensors inserted into the skin to measure the blood sugar concentration in the interstitial fluid, and send blood sugar data to external devices in real time through wireless communication of the transmitter for patients to view. This detection method is called continuous blood sugar monitoring (CGM). The external device then sends the required insulin infusion amount to the insulin pump via wireless communication and injects insulin subcutaneously, thus forming a blood sugar management system.

[0004] In the prior art, before establishing a wireless communication connection between an external device (referred to as a program module in this solution) and an on-body functional device such as a blood glucose detection device (referred to as a detection module in this solution) and / or an insulin pump (referred to as an infusion module in this solution), the patient often needs to input the device identifier of the blood glucose detection device and / or the insulin pump so that the external device can identify the broadcast signal of the blood glucose detection device and / or the insulin pump. The operation of inputting the device identifier is cumbersome and inconvenient for the patient. Even if some of the prior art adopts a solution of establishing a wireless communication connection without inputting the device identifier, the reliability of the wireless communication connection is not high because it is impossible to effectively distinguish the patient's own device from other patients' devices. Moreover, if the patient fails to establish a wireless communication connection between the external device and the on-body functional device in a timely manner, the patient may move with the on-body functional device during subsequent operations, increasing the possibility of being close to other patients' on-body functional devices, which is not conducive to the patient continuing to operate the external device to establish a wireless communication connection with the on-body functional device.

[0005] Therefore, the prior art urgently needs a high-reliability blood glucose management system that establishes a wireless communication connection between an external device and an on-body functional device. Summary of the invention

[0006] An embodiment of the present invention discloses a blood glucose management system that establishes a wireless communication connection by combining time and signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. During the process of the patient operating to establish a wireless communication connection, timing is carried out. The program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast signal with a strength not less than the preset signal strength threshold is searched within the time threshold, the program module can establish a wireless communication connection with the detection module and / or infusion module that sends the broadcast signal without inputting a device identifier. On the contrary, if the program module fails to establish a wireless communication connection with the detection module and / or infusion module within the time threshold, the patient can input a device identifier in the program module to establish a wireless communication connection, ensuring the reliability of the program module to establish a wireless communication connection with the patient's own detection module and / or infusion module.

[0007] The present invention discloses a blood glucose management system, including a body-mounted functional module pasted on the patient's skin surface, and each body-mounted functional module includes a unique device identifier; a program module for searching for nearby broadcast signals and identifying the signal strength of the broadcast signals, and the signal strength of the broadcast signals maps the distance between the program module and the body-mounted functional module; wherein, a time threshold and a signal strength threshold are preset in the blood glucose management system, the program module compares the broadcast signal strength with the preset signal strength threshold. If a broadcast signal with a strength not less than the preset signal strength threshold is searched within the preset time threshold, the program module establishes a wireless communication connection with the body-mounted functional module of the broadcast signal and conducts data interaction. Otherwise, the patient is required to input a device identifier in the program module to establish a wireless communication connection.

[0008] According to one aspect of the present invention, the body-mounted functional module includes a detection module and / or an infusion module. The detection module is used for continuously detecting the patient's current blood glucose value, and the infusion module is used for infusing the currently required insulin into the patient's body.

[0009] According to one aspect of the present invention, when the signal strength of the searched broadcast signal is not less than the preset signal strength threshold, the distance between the program module and the body-mounted functional module is 0 - 0.5 m.

[0010] According to one aspect of the present invention, when the signal strength of the searched broadcast signal is not less than the preset signal strength threshold, the distance between the program module and the body-mounted functional module is 0 - 0.3 m.

[0011] According to one aspect of the present invention, the time threshold is 0 - 600 seconds.

[0012] According to one aspect of the present invention, the time threshold is 0 - 60 seconds.

[0013] According to one aspect of the present invention, it further includes a code corresponding to a preset signal strength threshold, each code corresponding to a different preset signal strength threshold, and inputting the code in the program module can set the preset signal strength threshold.

[0014] According to one aspect of the present invention, the code is located in the device identifier of the on-body functional device.

[0015] According to one aspect of the present invention, the signal strength threshold is set in the program module.

[0016] According to one aspect of the present invention, the signal strength threshold is set in the on-body functional module, and the broadcast signal includes information associated with the preset signal strength threshold.

[0017] According to one aspect of the present invention, within the time threshold, when there is only one broadcast signal whose searched signal strength is not less than the preset signal strength threshold, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal; when the number of broadcast signals whose searched signal strength is not less than the preset signal strength threshold exceeds one, the program module does not establish a wireless communication connection with the on-body functional module that sends the broadcast signal.

[0018] According to one aspect of the present invention, when the number of broadcast signals whose searched signal strength is not less than the preset signal strength threshold exceeds one, the blood glucose management system prompts the patient to change the operation location or input the device identifier of the on-body functional module.

[0019] According to one aspect of the present invention, the time threshold is set in the on-body functional module or the program module.

[0020] According to one aspect of the present invention, the program module further includes a signal correction coefficient, the signal correction coefficient is associated with the state of the program module, and before the program module compares the broadcast signal strength with the preset signal strength threshold, the broadcast signal strength is corrected based on the signal correction coefficient.

[0021] According to one aspect of the present invention, before the on-body functional module and the program module establish a wireless communication connection, the patient's confirmation is required.

[0022] Compared with the prior art, the technical solution of the present invention has the following advantages:

[0023] In the blood glucose management system disclosed by the present invention, a signal strength threshold and a time threshold are preset in the blood glucose management system. During the process of the patient operating to establish a wireless communication connection, timing is carried out. The program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast signal with a strength not less than the preset signal strength threshold is searched within the time threshold, the program module can establish a wireless communication connection with the detection module and / or infusion module that sends the broadcast signal without inputting a device identifier. On the contrary, if the program module fails to establish a wireless communication connection with the detection module and / or infusion module within the time threshold, the patient can input the device identifier in the program module to establish a wireless communication connection, ensuring the reliability of the program module to establish a wireless communication connection with the patient's own detection module and / or infusion module.

[0024] Furthermore, the preset signal strength threshold can also be encoded in the device identifier of the detection module and / or infusion module, or printed on the detection module and / or infusion module or its packaging. Different encodings correspond to different preset signal strength thresholds, and further correspond to different maximum distances for establishing a wireless communication connection, which is convenient for further distinguishing from the devices of other patients and ensures the reliability of establishing a wireless communication connection for the patient's device.

[0025] Furthermore, the program module can also identify the number of broadcast signals with a signal strength exceeding the preset signal strength threshold. When there is only one signal, the program module establishes a wireless communication connection with the detection module and / or infusion module. When there are more than one signal, the program module does not establish a communication connection with the detection module and / or infusion module to avoid the program module establishing a communication connection with the wrong detection module and / or infusion module. At the same time, the detection module and / or infusion module can also prompt the patient to change the operation location to avoid other irrelevant broadcast signals as much as possible and improve the reliability of establishing a wireless communication connection.

[0026] Furthermore, the preset signal strength threshold can be set in the program module, detection module or infusion module. When the preset signal strength threshold is set in the detection module or infusion module, the preset signal strength threshold is transmitted together with the broadcast signal. When the program module receives the broadcast signal, it also receives the preset signal strength threshold, and the program module can also compare the broadcast signal strength with the preset signal strength threshold, so as to realize establishing a wireless communication connection without inputting a device identifier. Setting the preset signal strength threshold in the detection module or infusion module can be associated with the state of the detection module or infusion module. Due to the differences in the hardware of different individuals of the detection module or infusion module, different preset signal strength thresholds need to be applied to facilitate the patient to operate at a comfortable distance to establish a wireless communication connection.

[0027] Further, a signal correction coefficient is set in the program module. For different individual program modules, or as the usage time of the program module increases, the recognition sensitivity of the program module to the signal strength is not fixed. The signal correction coefficient can correct the signal strength recognized by the program module to increase the accuracy of the program module's recognition of the signal strength and enhance the reliability of establishing a wireless communication connection. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a schematic diagram of the module relationship of a general blood glucose management system;

[0029] Figure 2 It is a schematic diagram of the structure of an integrated CGM according to an embodiment of the present invention;

[0030] Figure 3 It is a schematic diagram of the structure of a split CGM according to an embodiment of the present invention;

[0031] Figure 4a It is a schematic diagram of the structure of an integrated insulin pump according to an embodiment of the present invention;

[0032] Figure 4b It is a schematic diagram of the structure of a split insulin pump according to an embodiment of the present invention;

[0033] Figure 5a It is a schematic diagram of the main interface when the control system according to an embodiment of the present invention is in the first working mode;

[0034] Figure 5b It is a schematic diagram of the main interface when the control system according to an embodiment of the present invention is in the second working mode;

[0035] Figures 6a - 6c It is a schematic diagram of different operation diagrams for the control system according to an embodiment of the present invention to turn on the insulin pump function;

[0036] Figures 7a - 7c It is a schematic diagram of different operation diagrams for the control system according to an embodiment of the present invention to turn on the automatic mode function;

[0037] Figures 8a - 8b It is a schematic diagram of the APP interface before and after the control system according to an embodiment of the present invention turns on the automatic mode function;

[0038] Figure 9a It is a schematic diagram of the interface when the system according to an embodiment of the present invention turns on the big meal mode;

[0039] Figure 9b and 9c It is a schematic diagram of different interfaces when selecting regular and big meal in the big meal mode of the system according to an embodiment of the present invention;

[0040] Figure 9dSchematic diagram of the interface when the system according to an embodiment of the present invention enables the regular meal mode;

[0041] Figure 10 Process schematic diagram of the infusion strategy for pre-infusion and supplementary infusion according to an embodiment of the present invention;

[0042] Figures 11a - 11f Operation schematic diagram of establishing a wireless communication connection according to different embodiments of the present invention. Detailed implementation manners

[0043] As described above, before an external device (referred to as a program module in this solution) establishes a wireless communication connection with in-vivo functional devices such as a blood glucose detection device (referred to as a detection module in this solution) and / or an insulin pump (referred to as an infusion module in this solution), patients often need to input the device identifiers of the blood glucose detection device and / or the insulin pump for the external device to identify the broadcast signals of the blood glucose detection device and / or the insulin pump. The operation of inputting the device identifiers is cumbersome and inconvenient for patients. Even in some existing technologies, a solution of establishing a wireless communication connection without inputting the device identifier is adopted. Due to the inability to effectively distinguish the patient's own device from those of other patients, the reliability of the wireless communication connection is not high. And if the patient cannot establish a wireless communication connection between the external device and the in-vivo functional device in time, during subsequent operations, the patient may move with the in-vivo functional device, increasing the possibility of getting close to the in-vivo functional devices of other patients, which is disadvantageous for the patient to continue operating the external device to establish a wireless communication connection with the in-vivo functional device.

[0044] To solve this problem, the present invention provides a blood glucose management system that establishes a wireless communication connection by combining time and signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. During the operation of establishing a wireless communication connection by the patient, timing is performed. The program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If within the time threshold, a broadcast signal with a strength not less than the preset signal strength threshold is searched, the program module can establish a wireless communication connection with the detection module and / or the infusion module that sends the broadcast signal without inputting the device identifier. On the contrary, if the program module does not establish a wireless communication connection with the detection module and / or the infusion module within the time threshold, the patient can input the device identifier in the program module to establish a wireless communication connection, ensuring the reliability of the wireless communication connection between the program module and the patient's own detection module and / or infusion module.

[0045] Now, various exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings. It should be understood that unless otherwise specifically stated, the relative arrangements of components and steps, numerical expressions, and numerical values set forth in these embodiments should not be construed as limiting the scope of the present invention.

[0046] In addition, it should be understood that, for the sake of convenience in description, the sizes of the various components shown in the drawings are not necessarily drawn in actual proportional relationships. For example, the thickness, width, length, or distance of certain units may be enlarged relative to other structures.

[0047] The following description of the exemplary embodiments is merely illustrative and in no sense limits the present invention or its application or use. Technologies, methods, and devices known to those of ordinary skill in the relevant art may not be discussed in detail herein, but when applicable, these technologies, methods, and devices should be regarded as part of this specification.

[0048] It should be noted that similar reference numerals and letters denote similar items in the following drawings. Therefore, once an item is defined or illustrated in one drawing, further discussion thereof will not be required in the subsequent drawing descriptions.

[0049] Figure 1 It is a schematic diagram of the module relationship of a general blood glucose management system.

[0050] The blood glucose management system disclosed in the embodiments of the present invention mainly includes a detection module 100, a program module 101, and an infusion module 102.

[0051] The detection module 100 is used to continuously detect the current blood glucose value of the patient. Generally, the detection module 100 is a continuous glucose monitor (CGM), which can detect the current blood glucose value of the patient in real time, monitor the blood glucose changes, and send the current blood glucose information to the program module 101. The CGM includes an implantable sensor, the sensor is connected to a transmitter, and the transmitter also includes a memory, a processor, a communication interface, etc. The transmitter is at least used to transmit the blood glucose data information detected by the CGM, as well as the identifier information of the CGM, etc.

[0052] The infusion module 102 includes the mechanical structures and electronic control units necessary for infusing blood glucose regulating drugs such as insulin and glucagon, such as a drug storage cylinder, a driving structure, an infusion tube and an infusion needle, a power supply, a circuit board, etc., and is controlled by the program module 101. Generally, the infusion module 102 is an insulin pump, and the electronic control unit includes a transmitter, a memory, a processor, a communication interface, etc. According to the current insulin infusion amount data sent by the program module 101, the infusion module 102 infuses the current required insulin into the patient's body. At the same time, the infusion status of the infusion module 102 can also be fed back to the program module 101 in real time.

[0053] The program module 101 is used to control the operation of the detection module 100 and the infusion module 102. At least based on the blood glucose value detected by the detection module 100, the program module 101 generates an insulin infusion instruction and controls the infusion module 102 to perform infusion, including a memory, a processor, a communication interface, a display, a patient interface, etc. Programming instructions are stored in the memory, and the processor can execute the programming instructions in the memory. The program module 101 is respectively connected to the detection module 100 and the infusion module 102. Here, the connection includes conventional electrical connection or wireless connection.

[0054] The embodiments of the present invention do not limit the specific positions and connection relationships of the detection module 100, the program module 101 and the infusion module 102, as long as the foregoing functional conditions can be met.

[0055] For example, in an embodiment of the present invention, the three are electrically connected to each other to form an integral structure. Therefore, the three are pasted at the same position on the patient's skin. The three modules are connected into an integral and pasted at the same position, the number of patient skin pasting devices will be reduced, thereby reducing the interference to the patient's activities caused by pasting more devices; at the same time, the problem of the reliability of wireless communication between separated devices is effectively solved, further enhancing the patient experience.

[0056] For example, in another embodiment of the present invention, the program module 101 and the infusion module 102 are connected to each other to form an integral structure, while the detection module 100 is separately arranged in another structure. At this time, the detection module 100 and the program module 101 transmit wireless signals to each other to achieve connection. Therefore, the program module 101 and the infusion module 102 are pasted at a certain position on the patient's skin, while the detection module 100 is pasted at other positions on the patient's skin.

[0057] For example, in still another embodiment of the present invention, the program module 101 and the detection module 100 are connected to each other to form the same device, while the infusion module 102 is separately arranged in another structure. The infusion module 102 and the program module 101 transmit wireless signals to each other to achieve connection. Therefore, the program module 101 and the detection module 100 can be pasted at a certain position on the patient's skin, while the infusion module 102 can be pasted at other positions on the patient's skin.

[0058] For example, in yet another embodiment of the present invention, the three are respectively arranged in different structures. Therefore, the three are respectively pasted at different positions on the patient's skin. At this time, the program module 101 respectively transmits wireless signals to the detection module 100 and the infusion module 102 to achieve connection.

[0059] In yet another embodiment of the present invention, the three are respectively disposed in different structures. Therefore, the detection module 100 and the infusion module 102 are respectively pasted at different positions on the patient's skin, while the program module 101 does not need to be pasted on the skin. The control of the detection module 100 and the infusion module 102 is realized through a handheld or portable device, such as a PDM or a smart phone. At this time, the program module 101 respectively transmits wireless signals to and receives wireless signals from the detection module 100 and the infusion module 102 to achieve mutual connection. In the embodiment of the present invention, the detection module 100 and the infusion module 102 can be collectively referred to as the on-body functional modules.

[0060] The wireless described in the foregoing embodiments can be, for example but not limited to, radio frequency (RF) communication (e.g., radio frequency identification (RFID), Zigbee communication protocol, WiFi, infrared, wireless universal serial bus (USB), ultra-wideband (UWB), communication protocols, and cellular communication, such as code division multiple access (CDMA) or global system for mobile communications (GSM).

[0061] Figure 2 Schematic diagram of the structure of an integrated CGM according to an embodiment of the present invention. Figure 3 Schematic diagram of the structure of a split CGM according to an embodiment of the present invention.

[0062] The CGM includes a sensor and a transmitter, which are installed on the patient through an auxiliary installer and penetrate under the skin. The sensor is used to collect the blood glucose content in the human body and transmit the collected blood glucose content information. The transmitter is connected to the sensor and is used to receive the blood glucose data information transmitted by the sensor implanted under the skin and convert it into a wireless signal for output. Each CGM has a unique identifier, such as a device identifier, a hardware identifier, a universally unique identifier, a serial number, an identifier based on a communication protocol (e.g., BLE ID), a manufacturer's identifier, etc. The identifier is formed by a random combination of multiple digits and letters and can be set on the housing or packaging of the CGM, and can also be set differently according to different types of CGMs.

[0063] Figure 2 Schematic diagram of the structure of an integrated CGM. That is, before use, the sensor and the transmitter of the CGM have been integrated together and are disposable products. After use, they are discarded, as Figure 2 shown. The integrated CGM includes a sensor 201, a housing 202, and a transmitter (not shown in the figure) disposed in the housing 202. The sensor 301 is used to detect the blood glucose data information of the patient's body fluid, transmit the above blood glucose data information to the transmitter through an internal circuit, and then send it to the receiver by the transmitter. The identifier can be set on the outer housing of the CGM, or on the outer packaging, or inside the CGM.

[0064] Figure 3 It is a schematic structural diagram of a split - type CGM. That is, before use, the sensor and the transmitter of the CGM are two different components, separately packaged, and integrated together only during use. The split - type CGM includes a bottom shell 301 and a transmitter 302. A sensor 3011 is provided on the bottom shell. The transmitter 302 has a separate housing. Engaging structures 3012 and 3022 are respectively provided on the housings of the bottom shell 301 and the transmitter 302. During use, the bottom shell 301 and the transmitter 302 are snap - fitted into a whole through the engaging structure. The sensor 3011 forms an electrical connection with the transmitter 302 through an electrical connector 3013. The sensor 301 is used to detect the blood glucose data information of the patient, and transmits the above - mentioned blood glucose data information to the transmitter 302 through the electrical connector 3013, and then is sent to the receiver by the transmitter 302.

[0065] In an embodiment of the present invention, both the sensor and the transmitter of the split - type CGM are disposable products and are discarded after use. Therefore, the identifier can be set on the housing of the sensor or the transmitter or on the outer packaging. In another embodiment of the present invention, only the sensor of the split - type CGM is a disposable product, while the transmitter is a reusable product. Therefore, preferably, in this embodiment, the identifier is set on the housing of the transmitter or on the outer packaging, which can reduce the binding frequency of patient information and the identifier and improve the patient experience. This will be described in detail below.

[0066] When the identifier is set on the housing or the outer packaging of the CGM or the transmitter, it can be set in the form of, but not limited to, a QR code, a barcode, or an NFC tag.

[0067] Figure 4a It is a schematic structural diagram of an integrated insulin pump according to an embodiment of the present invention; Figure 4b It is a schematic structural diagram of a split - type insulin pump according to an embodiment of the present invention.

[0068] In an embodiment of the present invention, the insulin pump is a patch - type insulin pump, that is, an insulin pump without a long catheter, including an infusion structure and a control structure, and is integrally pasted on the patient's skin surface by the same sticky patch. The drug is directly infused subcutaneously from the drug reservoir along the infusion needle.

[0069] Each insulin pump has a unique identifier, such as a device identifier, a hardware identifier, a universally unique identifier, a serial number, an identifier based on a communication protocol, a manufacturer's identifier, etc. The identifier is formed by a random combination of multiple digits and letters, and can be set on the housing or the packaging of the insulin pump, and can also have different settings according to different types of insulin pumps.

[0070] Figure 4aIt is a schematic structural diagram of an integrated insulin pump, that is, the infusion structure 410 and the control structure 400 of the insulin pump are arranged inside the same housing 10, the two are connected by wires, and are pasted at a certain position on the patient's skin through an adhesive patch 420, and are discarded as a whole after single use; the identifier can be set on the outer housing of the insulin pump, or on the outer packaging, or inside the insulin pump.

[0071] Figure 4b It is a schematic structural diagram of a split insulin pump, that is, the infusion structure 410 and the control structure 400 of the insulin pump are respectively arranged in two different housings, and the two are connected by a waterproof plug or directly snapped together and electrically connected to form a whole. The identifier can be set on the outer housing of the infusion structure and / or the control structure, or on the outer packaging, or inside the insulin pump.

[0072] In an embodiment of the present invention, both the infusion structure and the control structure of the split insulin pump are disposable products and are discarded after use. Therefore, the identifier can be set on the housing of the infusion structure and / or the control structure, or on the outer packaging. In another embodiment of the present invention, only the infusion structure of the split insulin pump is a disposable product, while the control structure is a reusable product. Therefore, preferably, in this embodiment, the identifier is set on the housing of the control structure or on the outer packaging, which can reduce the binding frequency of patient information and the identifier and improve the patient experience. This will be described in detail below.

[0073] When the identifier is set on the housing or outer packaging of the insulin pump or the control structure, it can be set in the form of, including but not limited to, a QR code, a barcode, or an NFC tag.

[0074] According to the different degrees of illness and the physical health status of the patient, some patients may only need CGM for continuous blood glucose monitoring, and some patients not only need CGM for continuous blood glucose monitoring, but also need an insulin pump for drug infusion. When the doctor determines that the patient only needs to use CGM for continuous blood glucose monitoring, since CGM only involves the detection of the patient's blood glucose, the patient's self-use of CGM will not pose a risk to the patient's life safety. Therefore, the patient can purchase CGM by himself. Before the CGM is installed on the patient's skin surface, the patient can search and download a dedicated APP for controlling the CGM in the application store of the smart phone, create a new account on the dedicated APP, and pair the patient's personal information with the information of the CGM to be worn, so as to realize the pairing and control of the smart phone and the CGM. The CGM and the insulin pump in the embodiment of the present invention are developed and produced by the same manufacturer, so they can be controlled by the same dedicated APP in the smart phone. Since not all patients need to use the insulin pump, only the content related to CGM is involved in the default main screen of the dedicated APP, such as Figure 5aAs shown, on the one hand, it can simplify the interface of the APP and provide a visual experience for patients. On the other hand, it can prevent patients from misoperating the insulin pump function and affecting the normal use of the CGM function.

[0075] In an embodiment of the present invention, when a doctor determines that a patient needs to use an insulin pump for drug infusion, as Figure 6a shown, the doctor sends an application to the background administrator, requesting to add the patient's account to the whitelist and allowing the patient to use the insulin pump function. The background administrator receives the whitelist addition application sent by the doctor, adds the patient's account to the whitelist list, and sends feedback to the doctor indicating that the whitelist addition has been completed. Further, the background administrator directly opens the insulin pump function on the APP interface used by the patient. At this time, the APP interface changes from Figure 5a to Figure 5b , Figure 5b The interface of Figure 5a has two additional function keys related to insulin infusion, "Insulin Delivery" and "Easyloop", compared to the interface of

[0076] In another embodiment of the present invention, when a doctor determines that a patient needs to use an insulin pump for drug infusion, as Figure 6b shown, the patient can directly send an application to the background administrator to turn on the insulin pump function. After receiving the application sent by the patient to turn on the insulin pump function, the background administrator will verify whether the patient's account is in the whitelist list. If the patient's account is in the whitelist list, the background administrator will open the insulin pump function on the APP interface used by the patient, and the APP interface changes from Figure 5a to Figure 5b ; if the patient's account is not in the whitelist list, a feedback message will be sent to the patient's account, reminding the patient to ask the doctor to send a whitelist addition application to the background administrator. When the doctor sends a whitelist addition application to the background administrator, the background administrator can directly open the insulin pump function on the APP interface used by the patient. If no information is received from the background administrator within a certain period of time, such as 1 minute, 2 minutes, or 5 minutes, the patient can send another application to the background administrator to turn on the insulin pump function, or ask the doctor to send a whitelist addition application to the background administrator. In another embodiment of the present invention, the background administrator does not directly open the insulin pump function on the APP interface used by the patient, but sends a security code to the patient's account, and the patient can open the insulin pump function on the APP interface when needed or convenient.

[0077] In another embodiment of the present invention, when a doctor determines that a patient needs to use an insulin pump for drug infusion, as Figure 6c shown, the doctor sends an application to the back-end administrator, requesting to add the patient's account to the whitelist to allow the patient to use the insulin pump function. The back-end administrator receives the whitelist addition application sent by the doctor, adds the patient's account to the whitelist list, and at the same time sends feedback to the doctor that the whitelist addition has been completed. Further, the doctor notifies the patient that the patient can apply to use the insulin pump function; after receiving the doctor's notice, the patient sends an application to the back-end administrator to turn on the insulin pump function. After receiving the application sent by the patient to turn on the insulin pump function, the back-end administrator directly opens the insulin pump function on the APP interface used by the patient. In another embodiment of the present invention, after receiving the application sent by the patient to turn on the insulin pump function, the back-end administrator can also first verify whether the patient's account exists in the whitelist. If it is determined that the patient's account is in the whitelist list, the back-end administrator opens the insulin pump function on the APP interface used by the patient. In another embodiment of the present invention, the back-end administrator does not directly open the insulin pump function on the APP interface used by the patient, but sends a security code to the patient's account. The patient can open the insulin pump function on the APP interface with the security code when needed or convenient.

[0078] When the doctor determines that the patient no longer needs to turn on the insulin pump function, the patient can turn off the insulin pump function on the APP by himself / herself, and the APP automatically sends information to the back-end administrator. The back-end administrator deletes the patient's account from the whitelist list; the doctor and / or the patient can also send an application to the back-end administrator, requesting to turn off the insulin pump function. The back-end administrator turns off the insulin pump function on the patient's account APP and at the same time deletes the patient's account from the whitelist list. When the patient needs to turn on the insulin pump function again, the patient's account needs to be added to the whitelist again in Figures 6a - 6c one of the ways.

[0079] It should be noted that when the insulin pump function of the APP is enabled, it is necessary to ensure that the insulin pump is correctly installed on the skin and the patient's personal information is paired with the information of the insulin pump, so as to realize the pairing and control between the smart phone and the insulin pump. The patient's personal information includes name, age, gender, mobile phone number, etc., and the information of the worn CGM and / or insulin pump includes the identifier information of the CGM and / or insulin pump. At the same time, the smart phone uploads the patient's personal information and the identifier information of the CGM and / or insulin pump to the remote server. The remote server can store the information uploaded by the smart phone and verify whether the identifier information of the CGM and / or insulin pump is valid. If a certain identifier information already exists in the remote server, the remote server sends a prompt to the smart phone to remind the patient that the CGM or insulin pump has been used and needs to be replaced. After the CGM and / or insulin pump is installed on the patient's skin and successfully activated, the CGM and / or insulin pump starts to work. The transmitter of the CGM sends the detected blood glucose information to the smart phone and further uploads it to the remote server. The control structure of the insulin pump receives the insulin infusion information and controls the infusion structure to infuse insulin, and at the same time sends the infusion status to the smart phone and further uploads it to the remote server.

[0080] It should be noted that the CGM and insulin pump in the embodiments of the present invention are developed and produced by the same manufacturer. Therefore, they can be controlled by the same dedicated APP in the smart phone. When the patient needs both the CGM and the insulin pump at the same time, even if it is assumed that the CGM or insulin pump produced by other manufacturers can also be directly controlled by the dedicated APP, it is possible to avoid the inconvenience caused to the patient by using different APPs to control the CGM and insulin pump respectively, and improve the patient experience.

[0081] When the worn CGM and / or insulin pump needs to be replaced due to reaching the usage period or failure, etc., the unique identifier information of the new CGM and / or insulin pump also needs to complete the pairing update with the patient's personal information through the smart phone and further upload it to the remote server. The input method of the patient's personal information is manual input, and the input method of the identifier information of the CGM and / or insulin pump can also be manual input or input in the form of scanning the QR code, bar code, or NFC tag on the shell or outer package of the CGM and / or insulin pump.

[0082] When the CGM is a split structure and the transmitter can be reused, the identifier of the CGM is set on the outer shell or package of the transmitter. When the patient replaces the CGM, only the sensor needs to be replaced, and the transmitter does not need to be replaced, and the identifier of the CGM also remains unchanged. Therefore, there is no need to update the pairing between the CGM identifier and the patient's personal information through the smart phone, nor to upload it to the remote server again. Therefore, the operation steps can be reduced and the patient experience can be improved.

[0083] When the insulin pump has a split structure and the control structure is reusable, the identifier of the insulin pump is set on the outer shell or packaging of the control structure. When the patient replaces the insulin pump, only the infusion structure needs to be replaced, and there is no need to replace the control structure. The identifier of the insulin pump also remains unchanged. Therefore, there is no need to update the pairing of the insulin pump identifier and the patient's personal information through the smartphone, nor to upload it to the remote server. Thus, the operation steps can be reduced and the patient experience can be improved.

[0084] There is wireless communication between the smartphone, the CGM and / or the insulin pump, and the remote server. The wireless communication can be, for example, but not limited to, radio frequency (RF) communication (such as radio frequency identification (RFID), Zigbee communication protocol, WiFi, infrared, wireless universal serial bus (USB), ultra-wideband (UWB), communication protocols and cellular communication, such as code division multiple access (CDMA) or global system for mobile communications (GSM). Preferably, there is WiFi and / or cellular communication between the smartphone and the remote server, and communication between the smartphone and the CGM and / or the insulin pump is through communication protocol.

[0085] When the doctor determines that the patient can turn on the automatic mode, that is, the APP reads the current blood glucose value detected by the CGM and the insulin information infused by the insulin pump, it can calculate the future trend of blood glucose and control the infusion of the insulin pump based on the calculated blood glucose trend, including increasing, decreasing, or stopping insulin infusion, so as to achieve the purpose of affecting the blood glucose value, and form an automated closed-loop control in a cycle. As Figure 7a shown, the doctor sends an application to the background administrator, requesting to add the patient's account to the whitelist and allowing the patient to use the automatic mode function. The background administrator receives the whitelist addition application sent by the doctor, adds the patient's account to the whitelist list, and at the same time sends feedback to the doctor that the whitelist addition has been completed. Further, directly open the automatic mode function of the APP interface used by the patient. At this time, the APP interface changes from Figure 8a to Figure 8b , Figure 8b The interface of Figure 8a compared to the interface of

[0086] In another embodiment of the present invention, when the doctor determines that the patient can turn on the automatic mode, as Figure 7bAs shown, the patient can directly send an application to enable the automatic mode function to the background administrator. After receiving the application sent by the patient to enable the automatic mode function, the background administrator will verify whether the patient's account is in the whitelist. If the patient's account is in the whitelist, the background administrator will turn on the automatic mode function of the APP interface used by the patient, and the APP interface changes from Figure 8a to Figure 8b ; if the patient's account is not in the whitelist, a feedback message will be sent to the patient's account, reminding the patient to ask the doctor to send an application to add the whitelist to the background administrator. When the doctor sends an application to add the whitelist to the background administrator, the background administrator can directly turn on the automatic mode function of the APP interface used by the patient. If no information from the background administrator is received within a certain period of time, such as 1 minute, 2 minutes, 5 minutes, the patient can send another application to enable the automatic mode function to the background administrator, or ask the doctor to send an application to add the whitelist to the background administrator. In another embodiment of the present invention, the background administrator does not directly turn on the automatic mode function of the APP interface used by the patient, but sends a security code to the patient's account, and the patient can turn on the automatic mode function of the APP interface through the security code when needed or convenient.

[0087] In yet another embodiment of the present invention, when the doctor determines that the patient needs to use the automatic mode, as Figure 7c shown, the doctor sends an application to the background administrator, requesting to add the patient's account to the whitelist and allowing the patient to use the automatic mode function. The background administrator receives the application to add the whitelist sent by the doctor, adds the patient's account to the whitelist, and at the same time sends feedback to the doctor that the whitelist addition has been completed. Further, the doctor notifies the patient that they can apply to use the automatic mode function; after receiving the doctor's notice, the patient sends an application to enable the automatic mode function to the background administrator. After receiving the application sent by the patient to enable the automatic mode function, the background administrator directly turns on the automatic mode function of the APP interface used by the patient. In another embodiment of the present invention, after receiving the application sent by the patient to enable the automatic mode function, the background administrator can also first verify whether the patient's account exists in the whitelist. If it is determined that the patient's account is in the whitelist, the background administrator will turn on the automatic mode function of the APP interface used by the patient. In another embodiment of the present invention, the background administrator does not directly turn on the automatic mode function of the APP interface used by the patient, but sends a security code to the patient's account, and the patient can turn on the automatic mode function of the APP interface through the security code when needed or convenient.

[0088] When the doctor determines that the patient no longer needs to turn on the automatic mode, the patient can turn off the automatic mode on the APP by himself / herself. The APP automatically sends information to the background administrator, and the background administrator deletes the patient's account from the whitelist. The doctor and / or the patient can also send an application to the background administrator to request to turn off the automatic mode. The background administrator turns off the automatic mode on the patient's APP and deletes the patient's account from the whitelist at the same time. When the patient needs to turn on the automatic mode again, the patient's account needs to be added to the whitelist again by referring to Figures 7a - 7c one of the methods.

[0089] In the embodiments of the present invention, the security code sent by the background when applying for the insulin pump function and the automatic mode function can be any number or combination of a series of numerical characters, alphabetical characters, and other symbols, and can also be a series of taps, a series of inputs, complex or simple gestures (for example, swiping or other movements on the touch screen, drawing an image), etc. In some cases, the security code can also include a quiz or a question set. The security code sent by the background each time is random.

[0090] Since the eating habits of people in different regions or different age groups vary greatly, when a unified control scheme is adopted, the blood glucose control effect of some people may be poor. Therefore, after the automatic mode function of the patient is turned on, the patient is required to enter a passcode to enter different automatic mode interfaces. For people with a large carbohydrate consumption, after entering the passcode, the automatic mode interface is as Figure 9a shown. The automatic mode interface shows a large meal option. The patient can choose whether to turn on the large meal module function by himself / herself. After the patient turns on the large meal mode function, the infusion page shows two options: "Regular" and "Large Meal", as Figure 9b and 9c shown. When the patient selects "Regular", the insulin infusion amount corresponding to the regular carbohydrate amount will be infused; when the patient selects "Large Meal", the insulin infusion amount corresponding to a larger carbohydrate amount will be infused. For people with a small carbohydrate consumption, after entering the passcode, the automatic mode interface is as Figure 9d shown. There is no large meal option on the interface, and the "Regular" mode is default, and the insulin infusion amount corresponding to the regular carbohydrate amount is infused.

[0091] In the embodiments of the present invention, the access code can be a small set of questions, such as "Are you a carbohydrate lover?", "Is your age within the range of A - B?", "Your gender?", "Your place of residence?", "Your fitness hobbies?", "Do you have any special diseases?", "Have you used the non - automatic mode before turning on the automatic mode?", etc. According to the patient's answers, the system automatically determines whether the patient is a person with a large carbohydrate consumption. In some other embodiments of the present invention, the access code is informed to the patient in advance by the doctor after diagnosing the patient, or the doctor sends the information on whether the patient is a person with a large carbohydrate consumption while sending an application for the automatic mode whitelist to the background administrator, and the background administrator automatically assigns the corresponding access code to the patient. The access code can be any number or combination of a series of numerical characters, alphabetical characters, and other symbols, and can also be a series of taps, a series of inputs, complex or simple gestures (for example, swiping or other movements on the touch screen, drawing an image), etc. The background administrator can send the access code to the patient when helping the patient turn on the automatic mode, or send the access code to the patient while sending the security code, or send the access code to the patient after confirming that the patient has turned on the automatic mode function through the security code. In the embodiments of the present invention, both the security code and the access code are randomly generated, and their generation rules can be the same or different. Preferably, the generation rules of the security code and the access code are different to avoid confusing the patient and causing trouble to the patient.

[0092] In the embodiments of the present invention, the system or the doctor's judgment on whether the patient is a person with a large carbohydrate consumption may be the result of a comprehensive judgment based on multiple factors such as the patient's age, eating habits, exercise habits, health status, and the result of using the non - automatic mode. When the patient has a usage record of the non - automatic mode, the usage record of the non - automatic mode is used as the main judgment basis.

[0093] When the patient selects meals, including "regular" and "big meal", the automatic mode adopts the drug infusion strategies of pre - infusion and supplementary infusion, as Figure 10 shown. During pre - infusion and supplementary infusion, for regular meals and big meals, the pre - infusion volume and the supplementary infusion volume are divided into different levels, as shown in Table 1 below:

[0094]

[0095] Among them, the insulin infusion amount during pre-infusion is at least related to the actual blood glucose value or the blood glucose change rate during pre-infusion, and the estimated meal amount. In other embodiments of the present invention, the pre-infusion amount may also be related to the IOB in the body; similarly, the insulin infusion amount during supplementary infusion is at least related to the actual blood glucose value or the blood glucose change rate during supplementary infusion, and the estimated supplementary meal amount. In other embodiments of the present invention, the supplementary infusion amount may also be related to the IOB in the body. In the embodiments of the present invention, the meal amount refers to the carbohydrate content in the meal.

[0096] The large, medium, and small sizes of the meal amount corresponding to pre-infusion and the large, medium, and small sizes of the meal amount corresponding to supplementary infusion are all independent parameters. The meal amount corresponding to pre-infusion of the same level is greater than the meal amount corresponding to supplementary infusion, but there is not necessarily a fixed corresponding relationship between them. The system can be set according to actual needs. For a large meal, the minimum value of the meal amount corresponding to pre-infusion is not less than the maximum value of the meal amount corresponding to a regular meal, and the minimum value of the meal amount corresponding to supplementary infusion is also not less than the maximum value of a regular meal.

[0097] Step 1001, the patient selects the meal type at time T0 and pre-infuses the default insulin infusion amount. The default insulin infusion amount for pre-infusion can be the pre-infusion insulin infusion amount corresponding to any large, medium, or small meal amount. Preferably, the default insulin infusion amount for pre-infusion is the insulin infusion amount corresponding to a small meal amount. Selecting a small initial supplementary insulin infusion amount can prevent excessive insulin infusion and reduce the risk of hypoglycemia.

[0098] Step 1002, at time T1, compare the current blood glucose value detected by CGM with a preset blood glucose threshold, such as 140, 150, 160, 170, 180, 190, 200 mg / mL, etc. If the current blood glucose value is greater than the preset blood glucose threshold, then infuse the default supplementary insulin infusion amount; otherwise, do not infuse the supplementary infusion amount. Among them, the default supplementary infusion amount can be the supplementary infusion insulin infusion amount corresponding to any large, medium, or small meal amount. Preferably, the default supplementary insulin infusion amount is the insulin infusion amount corresponding to a small meal amount. Selecting a small initial supplementary insulin infusion amount can prevent excessive insulin infusion and reduce the risk of hypoglycemia. Time T1 may be 1 h, 1.5 h, 2 h, 2.5 h, 3 h, etc. after time T0. In other embodiments of the present invention, the blood glucose change rate at time T1 can also be combined to determine whether to perform supplementary infusion.

[0099] Step 1003, within the time period of ΔT0 after time T0, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next pre-infusion is upgraded, that is, the insulin infusion amount corresponding to a larger estimated meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body; if the patient has hypoglycemia, the next pre-infusion is downgraded, that is, the insulin infusion amount corresponding to a smaller estimated meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body; if the patient has neither hyperglycemia nor hypoglycemia, the next pre-infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body.

[0100] It should be noted that in the embodiment of the present invention, the change in the infusion level means the change in the level of the estimated meal amount during infusion, while considering the actual blood glucose value or blood glucose change rate at the infusion time, or the IOB in the body. Therefore, in the embodiment of the present invention, the change in the level of the estimated meal amount also means the change in the infusion level, that is, the infusion level and the level of the estimated meal amount can be understood as consistent.

[0101] Step 1004, within the time period of ΔT1 after time T1, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next supplementary infusion is upgraded, that is, the supplementary insulin infusion amount corresponding to a larger estimated meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body; if the patient has hypoglycemia, the next supplementary infusion is downgraded, that is, the insulin infusion amount corresponding to a smaller estimated supplementary meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body; if the patient has neither hyperglycemia nor hypoglycemia, the next supplementary infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same estimated supplementary meal amount is infused, while considering the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body.

[0102] Step 1005, the patient selects the meal type at time T2 and performs pre-infusion according to the result of Step 1003, that is, pre-infuses the insulin infusion amount corresponding to a larger, smaller or unchanged estimated meal amount, while considering the actual blood glucose value or blood glucose change rate at time T2, or the IOB in the body.

[0103] Step 1006, at time T3, compare the current blood glucose value detected by CGM with a preset blood glucose threshold, such as 140, 150, 160, 170, 180, 190, 200 mg / mL, etc. If the current blood glucose value is greater than the preset blood glucose threshold, then perform supplementary infusion according to the result of step 1004, that is, supplement the insulin infusion amount corresponding to a larger, smaller or unchanged supplementary meal amount, and at the same time consider the actual blood glucose value or blood glucose change rate at time T3, or the IOB in the body. If the current blood glucose value is not greater than the preset blood glucose threshold, then no supplementary infusion is performed. In other embodiments of the present invention, the blood glucose change rate at time T3 can also be combined to determine whether to perform supplementary infusion.

[0104] Step 1007, within the time period of △T0 after time T2, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, then the next pre-infusion is upgraded, that is, the insulin infusion amount corresponding to a larger estimated meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body; if the patient has hypoglycemia, then the next pre-infusion is downgraded, that is, the insulin infusion amount corresponding to a smaller estimated meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body; if the patient has neither hyperglycemia nor hypoglycemia, then the next pre-infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next pre-infusion time, or the IOB in the body.

[0105] Step 1008, within the time period of △T1 after time T3, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, then the next supplementary infusion is upgraded, that is, the supplementary insulin infusion amount corresponding to a larger supplementary estimated meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body; if the patient has hypoglycemia, then the next supplementary infusion is downgraded, that is, the insulin infusion amount corresponding to a smaller supplementary estimated meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body; if the patient has neither hyperglycemia nor hypoglycemia, then the next supplementary infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same supplementary meal amount is infused, and at the same time consider the actual blood glucose value or blood glucose change rate at the next supplementary infusion time, or the IOB in the body.

[0106] When pre-infusion and supplementary infusion are required at the next moment, repeat steps 1005 - 1008.

[0107] Generally, to maintain the stability of the patient's blood glucose level, the type of meal selected by the patient at time T2 is the same as that at time T0. That is, if the patient selects a regular meal at time T0, then a regular meal is also selected at time T2. If a large meal is selected at time T0, then a large meal is also selected at T2. Therefore, the next pre-infusion insulin selection and the supplementary insulin infusion selection can both depend on the results of the previous pre-infusion insulin selection and the supplementary insulin infusion selection. However, if the patient's next meal selection is inconsistent with the previous meal selection, then the patient returns to the initial default pre-infusion volume and default supplementary infusion volume at the next pre-infusion and supplementary infusion times to prevent inaccurate insulin infusion due to changes in the meal pattern.

[0108] Here, it should be noted that if the meal amount corresponding to the current pre-infusion volume is already the largest meal amount in the selected meal type, and hyperglycemia occurs within the △T0 time after time T0, then the next pre-infusion volume is not upgraded, and the insulin infusion amount corresponding to the large estimated meal amount is still pre-infused. At the same time, the actual blood glucose value or blood glucose change rate, or the in-body IOB at the next pre-infusion time is considered. Similarly, if the meal amount corresponding to the current pre-infusion volume is already the smallest meal amount in the selected meal type, and hypoglycemia occurs within the △T0 time after time T0, then the next pre-infusion volume is not downgraded, and the insulin infusion amount corresponding to the small estimated meal amount is still pre-infused. At the same time, the actual blood glucose value or blood glucose change rate, or the in-body IOB at the next pre-infusion time is considered.

[0109] Similarly, if the meal amount corresponding to the current supplementary infusion volume is already the largest meal amount in the selected meal type, and hyperglycemia occurs within the △T0 time after time T0, then the next supplementary infusion volume is not upgraded, and the insulin infusion amount corresponding to the large supplementary estimated meal amount is still pre-infused. At the same time, the actual blood glucose value or blood glucose change rate, or the in-body IOB at the next supplementary infusion time is considered. Similarly, if the meal amount corresponding to the current supplementary infusion volume is already the smallest supplementary meal amount in the selected meal type, and hypoglycemia occurs within the △T0 time after time T0, then the next supplementary infusion volume is not downgraded, and the insulin infusion amount corresponding to the small supplementary estimated meal amount is still supplementary infused. At the same time, the actual blood glucose value or blood glucose change rate, or the in-body IOB at the next supplementary infusion time is considered.

[0110] In other embodiments of the present invention, the meal amounts corresponding to pre-infusion and supplementary infusion do not necessarily have to be graded. That is, it is possible that the estimated meal amount during pre-infusion is only the default amount, while during supplementary infusion, the estimated meal amounts are divided into three different levels: large, medium, and small. Therefore, during the pre-infusion stage, each pre-infusion only infuses the insulin infusion amount corresponding to the default meal amount; or the estimated meal amounts during pre-infusion are divided into three different levels: large, medium, and small, while during supplementary infusion, the estimated meal amount is only the default amount. Therefore, during supplementary infusion, each supplementary infusion only infuses the insulin infusion amount corresponding to the default meal amount.

[0111] Similarly, the settings of the estimated meal amounts corresponding to pre-infusion and supplementary infusion in large meals and regular meals do not necessarily have to be the same. That is, for each meal pattern, the estimated meal amount corresponding to pre-infusion and the estimated meal amount corresponding to supplementary infusion can both be selected to be graded or not graded (default amount), and can be set according to the actual needs of the patient.

[0112] In an embodiment of the present invention, a small meal mode, that is, a snack mode, is also set in the system. When the patient selects the snack mode, since the range of carbohydrate content in snacks is relatively small, the system infuses insulin based on the default estimated meal amount, while considering the patient's actual blood glucose value or blood glucose change rate when eating snacks, as well as the IOB in the body. Moreover, the default estimated meal amount in the snack mode is less than the lowest-level estimated meal amount in the regular mode.

[0113] Establish a wireless communication connection

[0114] Figures 11a - 11f Schematic diagram of the operation of establishing a wireless communication connection for different embodiments of the present invention.

[0115] In the blood glucose management system, when the program module 101 is an external device such as a smart phone, PDM, or tablet computer, in order to facilitate the patient to use the artificial pancreas system, a wireless communication method is used for data transmission and interaction between the on-body functional modules (detection module 100 and / or infusion module 102) and the program module 101. Before formally establishing a wireless communication connection, the detection module 100 and / or the infusion module 102 send a broadcast signal, and the program module 101 searches for the broadcast signal and identifies the content and signal strength of the broadcast signal.

[0116] In the prior art, a patient needs to obtain the unique device identifier of the detection module 100 and / or the infusion module 102, and input the device identifier into the program module 101 to identify the broadcast signal of the detection module 100 and / or the infusion module 102 and establish a wireless communication connection. This step may be rather troublesome, time-consuming and laborious for the patient. Therefore, before establishing a communication connection, some detection modules 100 or infusion modules 102 can send broadcast signals. When the program module 101 searches for these broadcast signals, it can directly establish a communication connection with the signal source. This method omits the step of the patient inputting the device identifier of the detection module 100 and / or the infusion module 102, which is convenient for the patient to use. However, when the patient is in a complex usage environment, for example, in places where multiple patients are likely to gather such as a hospital or a consulting room, when the patient's program module 101 searches for the broadcast signals of the detection module 100 and / or the infusion module 102, it may search for the broadcast signals emitted by the detection module 100 and / or the infusion module 102 of other patients. The patient's program module 101 may thus connect to the wrong detection module 100 and / or infusion module 102, which may cause the patient's program module 101 to receive the blood glucose detection data of other patients, or send incorrect infusion instructions to the infusion module 102 of other patients, while its own infusion module 102 cannot receive the correct infusion instructions. This is disadvantageous to the patient.

[0117] In view of the above problems, in some embodiments of the present invention, considering that when the patient establishes a wireless communication connection between his own program module 101 and the detection module 100 and / or the infusion module 102, the program module 101 and the detection module 100 and / or the infusion module 102 will surely be placed beside himself. That is to say, the patient's own detection module 100 and / or infusion module 102 is closer to the patient's own program module 101 than the detection module 100 and / or infusion module 102 of other patients. Then, when the program module 101 searches for the broadcast signal of the patient's own detection module 100 and / or infusion module 102, the signal strength it obtains is stronger. And if the patient intentionally makes his own program module 101 search for a stronger broadcast signal strength to distinguish it from the broadcast signals of other patients, the patient can also actively place his own program module 101 closer to his own detection module 100 and / or infusion module 102. The specific implementation manners will be described below.

[0118] When the program module 101 establishes a wireless communication connection with the detection module 100 and / or the infusion module 102, Bluetooth is generally used as the communication protocol. According to the following calculation formula of the Bluetooth signal strength and distance, the distance between the program module 101 and the detection module 100 and / or the infusion module 102 can be mapped according to the Bluetooth signal strength searched by the program module 101.

[0119]

[0120] Wherein:

[0121] d is the distance between the program module 101 and the detection module 100 and / or the infusion module 102;

[0122] RSSI is the signal strength received by the program module 101, and this value is negative;

[0123] A is the signal strength received by the program module 101 when it is 1 meter away from the detection module 100 and / or the infusion module 102;

[0124] n is the environmental attenuation factor.

[0125] According to the calculation formula (1), it can be known that according to the signal strength received by the program module 101, the distance d between the program module 101 and the detection module 100 and / or the infusion module 102 can be determined. The stronger the broadcast signal strength received by the program module 101, the smaller the value of the distance d, which means that the patient's program module 101 is closer to the detection module 100 and / or the infusion module 102. On the contrary, when the patient holds the program module 101 close to his own detection module 100 and / or infusion module 102, the broadcast signal strength of the program module 101 searching for its own detection module 100 and / or infusion module 102 gradually increases. At the same time, the broadcast signal strength of the detection module 100 and / or infusion module 102 of other patients searched is gradually weakened. Based on this, the program module 101 can distinguish its own detection module 100 and / or infusion module 102 from the detection module 100 and / or infusion module 102 of other patients, and avoid establishing a wireless communication connection with the wrong detection module 100 and / or infusion module 102.

[0126] Generally speaking, for the detection module 100 or the infusion module 102, as long as its model and parameters do not change, after it is powered on at the factory, the power of the broadcast signal sent is fixed, and the signal strength of the broadcast signal decreases with the distance according to the calculation formula (1). Therefore, when the program module 101 searches for the broadcast signal, the relative distance between the program module 101 and the detection module 100 or the infusion module 102 can be obtained according to the signal strength of the identified broadcast signal.

[0127] It should be noted that the above calculation formula (1) is only used in this solution as an indication of the signal strength and the relative distance Exemplary descriptions may incorporate or use other calculation methods in actual product applications.

[0128] Refer to Figure 11a , in some embodiments of the present invention, a signal strength threshold RSSI can be preset in the program module 101 T , and the broadcast signal of the detection module 100 corresponds to the signal strength threshold RSSIT100 The broadcast signal of the infusion module 102 corresponds to the signal strength threshold RSSI T102 When the patient operating program module 101 approaches his own detection module 100 and / or infusion module 102, the signal strength RSSI received by the program module 101 gradually increases until it is not less than the preset signal strength threshold RSSI T100 and / or RSSI T102 When this happens, it can be considered that the signal source of this signal is the patient's own detection module 100 and / or infusion module 102. At this time, the patient no longer needs to input the device identifier of the detection module 100 and / or infusion module 102, and can directly establish a wireless communication connection between the program module 101 and the detection module 100 and / or infusion module 102, which facilitates the patient's use.

[0129] In some other embodiments of the present invention, the signal strength threshold RSSI can also be preset in the detection module 100 T100 and / or the signal strength threshold RSSI is preset in the infusion module 102 T102 When the detection module 100 and / or infusion module 102 sends a broadcast signal, the broadcast signal carries information related to the preset signal strength threshold RSSI T100 and / or RSSI T102 After the program module 101 searches for the broadcast signal and identifies the strength of the broadcast signal, it also needs to identify the preset signal strength threshold RSSI carried in the broadcast signal T100 and / or RSSI T102 Then, the signal strength of the broadcast signal is compared with the preset signal strength threshold RSSI T100 and / or RSSI T102 If the signal strength of the broadcast signal is not less than the preset signal strength threshold RSSI it carries T100 and / or RSSI T102 It indicates that the detection module 100 and / or infusion module 102 sending this broadcast signal is relatively close to the program module 101. It can be considered that the signal source of this signal is the patient's own detection module 100 and / or infusion module 102. At this time, the patient no longer needs to input the device identifier of the detection module 100 and / or infusion module 102, and can directly establish a wireless communication connection between the program module 101 and the detection module 100 and / or infusion module 102, which facilitates the patient's use. When the detection module 100 and / or infusion module 102 leave the factory, the preset signal strength threshold RSSI T100 and / or RSSI T102It is set in the detection module 100 and / or the infusion module 102. The preset signal strength threshold RSSI suitable for the individual of the detection module 100 and / or the infusion module 102 can be set according to characteristics such as the hardware status, type, and parameters of the individual of the detection module 100 and / or the infusion module 102 T100 and / or RSSI T102 . For detection modules 100 and / or infusion modules 102 with different characteristics such as hardware status, type, and parameters, the power of the broadcast signal sent is different. In this way, when the patient operates to establish a wireless communication connection, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 is also different. To increase the operation convenience of the patient and maintain the consistency of habits, the preset signal strength threshold RSSI T100 and / or RSSI T102 suitable for the individual of the detection module 100 and / or the infusion module 102 is set, which can ensure that when the patient operates to establish a wireless communication connection, the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is appropriate and consistent, increasing the operation convenience for the patient and improving the patient's usage experience.

[0130] In some embodiments of the present invention, establishing a wireless communication connection by the program module 101 identifying the signal strength sent by the detection module 100 and / or the infusion module 102 does not necessarily mean that the blood glucose management system closes the device identifier of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. The two ways of establishing a wireless communication connection can coexist, and the patient can choose a suitable way based on their own situation.

[0131] Referring to Figure 11b , in some embodiments of the present invention, the blood glucose management system provides two operation modes for the patient to establish a wireless communication connection at the same time. In the first operation mode, the patient operates the program module 101 to approach the detection module 100 and / or the infusion module 102. As described above, a wireless communication connection is established by the program module 101 identifying the signal strength sent by the detection module 100 and / or the infusion module 102. In the second operation mode, the patient inputs the device identifier of the detection module 100 and / or the infusion module 102 into the program module 101. The device identifier contains the broadcast signal information of the detection module 100 and / or the infusion module 102. Based on the device identifier, the corresponding broadcast signal can be identified, and thus a wireless communication connection is established.

[0132] In some embodiments of the present invention, the ways for the program module 101 to obtain the device identifier include but are not limited to the patient manually inputting characters, scanning a two-dimensional code, Bluetooth transmission, voice recognition, etc. Any way that can input the device identification code into the program module 101 can implement this solution.

[0133] In some embodiments of the present invention, when a patient expects to establish a wireless communication connection, the patient can select the first operation mode or the second operation mode on the interaction interface of the program module 101, and the first operation mode and the second operation mode are displayed in a side-by-side manner on the interaction interface of the program module 101.

[0134] In some embodiments of the present invention, the detection module 100 and / or the infusion module 102 can be an integrated or split structure. When the detection module 100 is a split structure, its transmitter can be reused. When the infusion module 102 is a split structure, its electronic control unit, such as Figure 4a and 4b the control structure 100 shown in, can be reused. In the embodiments of the present invention, the device identifier of the detection module 100 corresponds to its transmitter, and the device identifier of the infusion module 102 corresponds to its electronic control unit.

[0135] In the first operation mode, the broadcast signal carries information associated with the device identifier, and while the program module 101 recognizes the broadcast signal, it can obtain the device identifier information carried by the broadcast signal. After the patient successfully operates to establish a wireless communication connection, the program module 101 generates a whitelist profile of the object that can establish a wireless communication connection, and the whitelist profile stores relevant information of the detection module 100 and / or the infusion module 102 that has established a wireless communication connection, such as storing the device identifiers of the detection module 100 and / or the infusion module 102. If the patient operates again to establish a wireless communication connection with the old detection module 100 and / or infusion module 102 without replacing the transmitter or the electronic control unit, the program module 101 only needs to recognize the device identifier information carried in the broadcast signal. If it is consistent with the device identifier stored in its whitelist profile, the program module 101 can directly establish a wireless communication connection with the detection module 100 and / or the infusion module 102 that sends the broadcast signal, without the need to input the device identifier again, nor to recognize the signal strength of the broadcast signal, which is convenient for the patient to operate and improves the user experience.

[0136] In some embodiments of the present invention, the whitelist profile of the program module 101 can store one or more device identifiers.

[0137] In some embodiments of the present invention, when the patient does not want to establish a wireless communication connection with a certain old detection module 100 and / or infusion module 102 anymore, the patient can choose to modify or delete the corresponding whitelist profile, so that the program module 101 cannot directly establish a wireless communication connection with the detection module 100 and / or the infusion module 102. After the patient modifies or deletes the whitelist profile, if the patient needs to establish a wireless communication connection with the corresponding detection module 100 and / or infusion module 102 again, the patient needs to perform the first operation mode or the second operation mode again.

[0138] In some other embodiments of the present invention, when the patient operates again to establish a wireless communication connection, the patient can also choose to adopt the first operation mode or the second operation mode, and there is no restriction on the patient here.

[0139] In some embodiments of the present invention, when the program module 101 just searches for a broadcast signal with the same intensity as the preset signal strength threshold RSSI T100 and / or RSSI T102 the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is the maximum distance for establishing a wireless communication connection. If there is no change in the signal propagation medium, at any position within this maximum distance, the program module 101 can establish a wireless communication connection with the detection module 100 and / or the infusion module 102.

[0140] In some embodiments of the present invention, by setting the broadcast signal strength threshold RSSI T100 and / or RSSI T102 corresponding to the maximum distance, for example, the maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 can be set to 0.5 m. That is, when the distance between the program module 101 and the detection module 100 and / or the infusion module 102 does not exceed 0.5 m, the patient does not need to input the device identifier of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. Preferably, the above maximum distance is 0.3 m. Further preferably, the above maximum distance is 0.1 m. In the embodiments of the present invention, the smaller the distance between the program module 101 and the detection module 100 and / or the infusion module 102, the stronger the signal intensity of the detection module 100 and / or the infusion module 102 of the patient recognized by the program module 101, the easier it is to distinguish from the signals of other patients' devices, and the higher the reliability of the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 of the patient. However, if the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is too small, it may lead to low operation convenience for the patient. Selecting an appropriate signal strength threshold can determine a suitable distance for connecting a wireless communication connection.

[0141] In the above embodiments, when the broadcast signal intensities sent by the detection module 100 and / or the infusion module 102 after being powered on are the same, and the preset signal strength thresholds RSSI T100 and / or RSSI T102When it remains unchanged, each time the patient establishes a wireless communication connection during an operation, the maximum distance that the program module 101 identifies for the patient's own detection module 100 and / or infusion module 102 is also the same. In other embodiments of the present invention, the maximum distance that the program module 101 identifies for the patient's own detection module 100 and / or infusion module 102 can be adjusted.

[0142] For example, with reference to Figure 11c , in some embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 is pre-stored in the program module 101 when the program module 101 leaves the factory. The preset values of the signal strength threshold RSSI T100 and / or RSSI T102 in different program modules 101 can be different. When the patient operates to establish a wireless communication connection, the maximum distance that the program module 101 identifies for the patient's own detection module 100 and / or infusion module 102 is also different accordingly. When the patient operates the program module 101 closer to the detection module 100 and / or infusion module 102, after entering this maximum distance, a wireless communication connection can be established between the program module 101 and the detection module 100 and / or infusion module 102.

[0143] Alternatively, in other embodiments of the present invention, the available signal strength threshold RSSI T100 and / or RSSI T102 is pre-stored in the program module 101 in the form of a list profile. When the detection module 100 and / or infusion module 102 leaves the factory, the signal strength threshold RSSI T100 and / or RSSI T102 suitable for the status of the detection module 100 and / or infusion module 102 is encoded in the device identifier. Such encoding can consist of at least one digit, letter, special symbol, etc. character. Before the patient operates to establish a wireless communication connection, the patient can first input the encoding associated with the signal strength threshold RSSI T100 and / or RSSI T102 through the interaction interface of the program module 101, without the need to input the complete device identifier of the detection module 100 and / or infusion module 102. Different encoding mappings correspond to different signal strength thresholds RSSI T100 and / or RSSI T102 . When the patient inputs the encoding in the program module 101, the signal strength threshold RSSI T100 and / or RSSI T102and further corresponding to the program module 101 to identify different maximum distances of the patient's own detection module 100 and / or infusion module 102. When the patient operates the program module 101 to approach the detection module 100 and / or infusion module 102 and enters the maximum distance corresponding to this code, the program module 101 can establish a wireless communication connection with the detection module 100 and / or infusion module 102.

[0144] In some embodiments of the present invention, the above signal strength threshold RSSI T100 and / or RSSI T102 associated codes can be single characters, such as any Arabic numerals from 0-9, Greek numerals, or any letters from A-Z, or any punctuation marks, without limitation here. In an exemplary description, the Arabic numeral 5 represents a signal strength threshold RSSI T5 , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.5m. The Arabic numeral 3 represents another signal strength threshold RSSI T3 , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.3m. The letter A represents yet another signal strength threshold RSSI TA , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.05m. The above characters and their corresponding maximum distances are only for exemplary description.

[0145] In other embodiments of the present invention, the above signal strength threshold RSSI T100 and / or RSSI T102 associated codes can be at least two characters, which can be composed of or mixed with any Arabic numerals, Greek numerals, letters, or punctuation marks, etc., without limitation here. In an exemplary description, the Arabic numeral 25 represents a signal strength threshold RSSI T25 , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.25m. The Arabic numeral 21 represents another signal strength threshold RSSI T21 , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.21m. The letter 1A represents yet another signal strength threshold RSSI T1A , and the maximum distance for the program module 101 corresponding to this signal strength threshold to establish a wireless communication connection with the detection module 100 and / or infusion module 102 is 0.05m.

[0146] In some embodiments of the present invention, the above signal strength threshold RSSI T100 and / or RSSI T102 associated encoding can be symbols at any position of the device identifier, which can be continuous symbol encodings or discontinuous and jumping symbol encodings, and are not limited herein. In an exemplary description, the encoding 1**2******** represents a signal strength threshold RSSI T12 , where "*" represents the device identifier encoding, that is, the encoding corresponding to the signal strength threshold RSSI T12 is located at the 1st and 4th positions of the device identifier. The patient only needs to input "12" on the interaction interface of the program module 101, and the program module 101 will retrieve the signal strength threshold RSSI corresponding to the encoding "12" T12 .

[0147] In other embodiments of the present invention, the above signal strength threshold RSSI T100 and / or RSSI T102 associated encoding is printed separately on the detection module 100 and / or the infusion module 102 or on the packaging.

[0148] After being powered on, the detection module 100 and / or the infusion module 102 send broadcast signals at a normal power, which is called the first power here. In some existing technologies, in order to facilitate the patient to establish a wireless communication connection, the first power is usually set relatively large to ensure the effective distance of the broadcast signal for the program module 101 to search and identify. Sending broadcast signals at the first power for a long time consumes too much power for the detection module 100 and / or the infusion module 102, affecting the service life of the detection module 100 and / or the infusion module 102.

[0149] Referring to Figure 11d , in some embodiments of the present invention, in order to save the power consumption of the detection module 100 and / or the infusion module 102 and extend the service life, during the period when the detection module 100 and / or the infusion module 102 send broadcast signals after being powered on, the broadcast signal transmission power can be reduced, and the broadcast signal is sent at a second power, and the second power is less than the first power. For example, the second power is one-half or one-third of the first power. On this premise, if the preset signal strength threshold RSSI T100 and / or RSSI T102 remains unchanged, the program module 101 just searches for the broadcast signal strength to reach the preset signal strength threshold RSSI T100 and / or RSSI T102When this happens, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 will become smaller. For example, when the broadcast signal is sent at the first power, the maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 is 0.5 m. When the broadcast signal is sent at the second power, such as keeping the preset signal strength threshold RSSI T100 and / or RSSI T102 unchanged, the maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 may be reduced to 0.3 m or 0.1 m. Therefore, the patient needs to operate the program module 101 closer to the detection module 100 and / or the infusion module 102. After the program module 101 establishes a wireless communication connection with the detection module 100 and / or the infusion module 102, the detection module 100 and / or the infusion module 102 will increase the signal transmission power to maintain a long-distance wireless communication connection with the program module 101 at the third power. At this time, the effective communication distance between the program module 101 and the detection module 100 and / or the infusion module 102 is 0 - 10 m for the convenience of the patient's daily use.

[0150] In the above embodiments, the communication distance values are only for exemplary description, and different communication distance values may be applicable to different products and solutions.

[0151] After the detection module 100 and / or the infusion module 102 is powered on, it emits a broadcast signal at the first power. During the period when the patient operates the program module to establish a wireless communication connection with the detection module 100 and / or the infusion module 102, due to improper operation or interference by other things, the wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102 cannot be established in time, which increases the power consumption of the detection module 100 and / or the infusion module 102 and reduces the service life of the detection module 100 and / or the infusion module 102.

[0152] Regarding the above problems, referring to Figure 11e , in some embodiments of the present invention, a time threshold is set in the detection module 100 and / or the infusion module 102. After being powered on, a broadcast signal is sent with the first parameter and the timing starts. If the program module 101 does not establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the detection module 100 and / or the infusion module 102 will reduce the broadcast signal transmission parameter and send the broadcast signal with the second parameter. In the embodiments of the present invention, the "parameter" may correspond to power or time interval.

[0153] When the "parameter" corresponds to power, as mentioned above, the second power is less than the first power, for example, the second power is half or one third of the first power. At this time, the patient needs to operate the program module 101 closer to the detection module 100 and / or the infusion module 102 to establish a wireless communication connection.

[0154] In some embodiments of the present invention, the preset time threshold for the detection module 100 and / or the infusion module 102 to send the broadcast signal at the first power after power-on is set by the manufacturer or the patient, and can be set to 0-600 seconds. Preferably, the above time threshold is set to 0-60 seconds. The above values are only for exemplary description.

[0155] In other embodiments of the present invention, when the "parameter" corresponds to the time interval, if the program module 101 does not establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the power of the detection module 100 and / or the infusion module 102 to send the broadcast signal remains unchanged, but the sending time interval of the broadcast signal is adjusted. For example, within the preset time threshold, the first time interval between two adjacent broadcast signals is 0.01-10 seconds, and after exceeding the preset time threshold, the second time interval between two adjacent broadcast signals is 1-60 seconds. Preferably, after exceeding the preset time threshold, the sending time interval of the broadcast signal is increased, for example, before and after the preset time threshold, the sending time interval of two adjacent broadcast signals is increased from 0.1 seconds to 10 seconds. After increasing the sending time interval of the broadcast signal, the number of times the broadcast signal is sent per unit time is reduced, and the power consumption of the detection module 100 and / or the infusion module 102 can also be reduced, and the service life of the detection module 100 and / or the infusion module 102 can be extended. The longer the broadcast signal sending time interval is, the more power consumption is saved, but the longer the patient has to wait when operating to establish a wireless communication connection. Selecting an appropriate broadcast signal sending time interval can not only reduce power consumption but also satisfy the patient's usage experience.

[0156] In some embodiments of the present invention, in order to further reduce the power consumption of the detection module 100 and / or the infusion module 102, the transmission power of the broadcast signal may be reduced while increasing the transmission time interval of the broadcast signal.

[0157] In some embodiments of the present invention, if the patient is unable to establish a wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102 in a timely manner, the patient's own position may change when the patient performs subsequent operations to establish a wireless communication connection. The patient's own detection module 100 and / or infusion module 102 may be close to the detection modules 100 and / or infusion modules 102 of other patients, thereby increasing the risk of establishing an erroneous wireless communication connection, which is not conducive to the patient's operation to establish a wireless communication connection.

[0158] For the above questions, refer toFigure 11f In some embodiments of the present invention, a time threshold may be set in the detection module 100 and / or the infusion module 102, and timing starts after power-on. If the program module 101 fails to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the blood glucose management system adds a mode of establishing a wireless communication connection by inputting the device identifier of the detection module 100 and / or the infusion module 102 into the program module 101. At this time, if the patient continues to operate to establish a wireless communication connection, the patient can continue to operate the program module 101 to search for broadcast signals, or can input the device identifier of the detection module 100 and / or the infusion module 102 on the interaction interface of the program module 101, which reduces the possibility of the program module 101 connecting to the wrong detection module 100 and / or infusion module 102.

[0159] In other embodiments of the present invention, a time threshold may also be set in the program module 101. After the patient powers on the detection module 100 and / or the infusion module 102 and starts timing when operating to establish a wireless communication connection, if the program module 101 fails to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the patient can input the device identifier of the detection module 100 and / or the infusion module 102 into the program module 101 to establish a wireless communication connection. At this time, if the patient continues to operate to establish a wireless communication connection, the patient can continue to operate the program module 101 to search for broadcast signals, or can input the device identifier of the detection module 100 and / or the infusion module 102 on the interaction interface of the program module 101, which also reduces the possibility of the program module 101 connecting to the wrong detection module 100 and / or infusion module 102.

[0160] In some embodiments of the present invention, the above-mentioned preset time threshold of the device identifier is set by the manufacturer or the patient, and it can be set to 0 - 600 seconds. Preferably, the above time threshold is set to 0 - 60 seconds. The above values are only for exemplary description.

[0161] In some embodiments of the present invention, in some cases, when the patient operates the program module 101 to search for broadcast signals, the signal strengths of multiple broadcast signals may be recognized to be not less than the preset signal strength threshold RSSI T100 and / or RSSI T102 , in this case, the program module 101 will not be able to select a certain broadcast signal to establish a wireless communication connection, and will promptly prompt the patient that there are multiple connectable broadcast signals around, and the patient needs to change the operation location, or re-operate to establish a wireless communication connection until the program module 101 only recognizes that the signal strength of 1 broadcast signal is not less than the preset signal strength threshold RSSI T100 and / or RSSI T102, or prompt the patient to input the device identifier of the detection module 100 and / or the infusion module 102, so that the program module 101 establishes a wireless communication connection with the patient's own detection module 100 and / or infusion module 102.

[0162] In some embodiments of the present invention, in order to avoid the patient waiting for a long time during the operation of establishing a wireless communication connection, the program module 101 starts timing when it begins to search for and identify broadcast signals. For example, within 5 seconds after the program module 101 starts to search for and identify broadcast signals, if the program module 101 fails to identify a broadcast signal with a signal strength not less than the preset signal strength threshold, or identifies multiple broadcast signals with a signal strength not less than the preset signal strength threshold, the program module 101 will prompt the patient to re-operate to establish a wireless communication connection, or change the operation location. Within the next 20 seconds, if the program module 101 still fails to identify a broadcast signal with a signal strength not less than the preset signal strength threshold, or still identifies multiple broadcast signals with a signal strength not less than the preset signal strength threshold, the program module 101 will prompt the patient to input the device identification code of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection in this way. The above time values are only for exemplary description.

[0163] In some embodiments of the present invention, considering that the program module 101 at the signal receiving end may also have differences in identifying broadcast signals with the same signal strength due to its individual state differences. For example, after the program module 101 leaves the factory, as the usage time goes by, its hardware gradually ages, and the recognition sensitivity to signal strength gradually decreases. And the program module 101 is generally a device that can be reused for a long time. The absolute strength recognition of broadcast signals by the program module 101 may change during use, and the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 may also change when the patient operates to establish a wireless communication connection, which may cause inconvenience to the patient's operation habits. Therefore, a signal correction coefficient can be set in the program module 101, and the arithmetic correction result of the broadcast signal strength identified by the program module 101 and the signal correction coefficient is used to finally determine the broadcast signal strength searched by the program module 101, and based on the corrected broadcast signal strength and the preset signal strength threshold RSSI T100 and / or RSSI T102 are compared to determine whether to establish a wireless communication connection. The corrected broadcast signal strength can ensure that when the patient operates to establish a wireless communication connection, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 does not change greatly, for example, the change range is between -0.05m and 0.05m, which can minimize the impact on the patient's operation habits.

[0164] In some embodiments of the present invention, the signal correction coefficient can be input into the patient input program module 101, or the signal correction coefficient is stored in the program module 101. As the usage time of the program module 101 increases, the signal correction coefficient can be adjusted over time.

[0165] In some embodiments of the present invention, the correction arithmetic between the broadcast signal strength and the signal correction coefficient is multiplication or addition, or other algorithms.

[0166] In some embodiments of the present invention, in order to further ensure the reliability of establishing a wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102, before establishing a wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102, the confirmation instruction of the patient is also required.

[0167] In summary, the present invention discloses a blood glucose management system that establishes a wireless communication connection by combining time and signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. Timing is performed during the patient's operation to establish a wireless communication connection. The program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast signal with a strength not less than the preset signal strength threshold is searched within the time threshold, the program module can establish a wireless communication connection with the detection module and / or the infusion module that sends the broadcast signal without inputting a device identifier. On the contrary, if the program module fails to establish a wireless communication connection with the detection module and / or the infusion module within the time threshold, the patient can input a device identifier in the program module to establish a wireless communication connection, ensuring the reliability of establishing a wireless communication connection between the program module and the patient's own detection module and / or infusion module.

[0168] Although some specific embodiments of the present invention have been described in detail by way of examples, those skilled in the art should understand that the above examples are for illustrative purposes only and not for limiting the scope of the present invention. Those skilled in the art should understand that the above embodiments can be modified without departing from the scope and spirit of the present invention. The scope of the present invention is defined by the appended claims.

Claims

1. A blood glucose management system, characterized in that, Including: On-body functional modules, which are pasted on the patient's skin surface, and each on-body functional module includes a unique device identifier; A program module, which is used to search for nearby broadcast signals and identify the signal strength of the broadcast signals, and the signal strength of the broadcast signals maps the distance between the program module and the on-body functional module; Among them, a time threshold and a signal strength threshold are preset in the blood glucose management system, and timing is carried out during the patient's operation to establish a wireless communication connection. The program module compares the broadcast signal strength with the preset signal strength threshold. If a broadcast signal with a strength not less than the preset signal strength threshold is searched within the preset time threshold, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal and conducts data interaction. Otherwise, the device identifier is input into the program module to establish a wireless communication connection.

2. The blood glucose management system according to claim 1, wherein The on-body functional module includes a detection module and / or an infusion module. The detection module is used to continuously detect the patient's current blood glucose value, and the infusion module is used to infuse the currently required drug into the patient's body.

3. The blood glucose management system according to claim 1, wherein When the searched broadcast signal strength is not less than the preset signal strength threshold, the distance between the program module and the on-body functional module is 0 - 0.5m.

4. The blood glucose management system according to claim 3, wherein When the searched broadcast signal strength is not less than the preset signal strength threshold, the distance between the program module and the on-body functional module is 0 - 0.3m.

5. The blood glucose management system according to claim 1, wherein The time threshold is 0 - 600 seconds.

6. The blood glucose management system according to claim 5, wherein The time threshold is 0 - 60 seconds.

7. The blood glucose management system according to claim 1, characterized in that, It also includes a code corresponding to the preset signal strength threshold. Each code corresponds to a different preset signal strength threshold, and inputting the code into the program module can set the preset signal strength threshold.

8. The blood glucose management system according to claim 7, wherein The code is related to the device identifier of the on-body functional device.

9. The blood glucose management system according to claim 1, wherein The signal strength threshold is set in the program module.

10. The blood glucose management system according to claim 1, characterized in that, The signal strength threshold is set in the on-body functional module, and the broadcast signal includes information associated with the preset signal strength threshold.

11. The blood glucose management system according to claim 1, wherein Within the time threshold, when there is only one broadcast signal with a signal strength not less than the preset signal strength threshold searched, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal. When the number of broadcast signals with a signal strength not less than the preset signal strength threshold searched exceeds one, the program module does not establish a wireless communication connection with the on-body functional module that sends the broadcast signal.

12. The blood glucose management system according to claim 9, characterized in that, When the number of broadcast signals with a signal strength not less than the preset signal strength threshold searched exceeds one, the blood glucose management system prompts the patient to change the operation location or input the device identifier of the on-body functional module.

13. The blood glucose management system according to claim 1, characterized in that, The time threshold is set in the on-body functional module or the program module.

14. The blood glucose management system according to claim 1, wherein, The program module also includes a signal correction coefficient, which is associated with the state of the program module. Before the program module compares the broadcast signal strength with the preset signal strength threshold, the broadcast signal strength is corrected based on the signal correction coefficient.

15. The blood glucose management system according to claim 1, wherein Before establishing a wireless communication connection between the functional module on the body and the program module, the patient's confirmation is required.

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