Breathing machine, pressure and tidal volume adjusting method, device and equipment thereof and medium

Abstract

The invention relates to a breathing machine, a pressure and tidal volume adjusting method, device and equipment thereof and a medium, and the method comprises the steps that the carbon dioxide concentration of the expiration tail end of a patient is obtained; determining a pressure compensation value of the breathing machine according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold value; real-time pressure of the breathing machine is obtained, and a target pressure value is obtained based on the pressure compensation value and the real-time pressure; calculating a target tidal volume according to the target pressure value; and adjusting the pressure and tidal volume of the breathing machine based on the target pressure value and the target tidal volume. In the whole process, the pressure and the tidal volume of the breathing machine are compensated / adjusted based on the carbon dioxide concentration of the exhalation tail end of the patient, the breathing machine can continuously and stably provide appropriate pressure and tidal volume support according to the actual exhalation carbon dioxide concentration of the patient, and stable adjustment of the pressure and the tidal volume of the breathing machine is achieved.

Description

Technical Field

[0001] The present application relates to the technical field of ventilators, and particularly to a ventilator and a method, device, computer device, storage medium, and computer program product for adjusting pressure and tidal volume thereof. Background Art

[0002] In modern medical technology, as a key device for assisting or replacing patients' spontaneous breathing, the performance of a ventilator is directly related to the treatment effect and life safety of patients. Among them, the precise adjustment of pressure and tidal volume is the core link of ventilator technology. At present, methods such as pressure control ventilation, pressure support ventilation, volume control ventilation, and pressure-regulated volume control ventilation are mainly adopted in the field of ventilators to achieve this goal. Pressure control ventilation realizes gas delivery through a constant preset pressure; pressure support ventilation assists breathing by setting two pressure levels, high and low; volume control ventilation emphasizes the precise supply of a preset tidal volume; and pressure-regulated volume control ventilation attempts to integrate the advantages of the former two, optimizing pressure control while ensuring the tidal volume.

[0003] Although the above methods meet the clinical needs to a certain extent, there are still many limitations. Specifically, in the pressure control ventilation mode, the tidal volume is easily affected by the fluctuations of the patient's lung compliance and airway resistance, resulting in unstable treatment; pressure support ventilation highly depends on the patient's spontaneous breathing ability, and its applicability is limited for patients with severely impaired respiratory function; although volume control ventilation can ensure the accurate supply of tidal volume, it may increase the risk of barotrauma due to excessive pressure fluctuations.

[0004] It can be seen that there is an urgent need for a stable ventilator pressure and tidal volume adjustment scheme at present. Summary of the Invention

[0005] Based on this, it is necessary to provide a stable method, device, computer device, computer-readable storage medium, and computer program product for adjusting the pressure and tidal volume of a ventilator in view of the above technical problems; in addition, a ventilator capable of realizing stable pressure and tidal volume adjustment is also provided.

[0006] In a first aspect, the present application provides a method for adjusting the pressure and tidal volume of a ventilator. The method includes:

[0007] Obtain the carbon dioxide concentration at the end of the patient's exhalation;

[0008] Determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold;

[0009] Obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value;

[0010] Calculate the target tidal volume according to the target pressure value;

[0011] Adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0012] In one embodiment, obtaining the carbon dioxide concentration at the end of the patient's exhalation includes:

[0013] Obtain the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales respectively;

[0014] Calculate the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales.

[0015] In one embodiment, the calculating the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales includes:

[0016] Calculate the carbon dioxide production and oxygen consumption according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales;

[0017] Calculate the respiratory quotient according to the carbon dioxide production and oxygen consumption;

[0018] Calculate the carbon dioxide concentration at the end of the patient's exhalation according to the respiratory quotient.

[0019] In one embodiment, the determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold includes:

[0020] Calculate the difference between the carbon dioxide concentration and the preset carbon dioxide concentration threshold to obtain the carbon dioxide concentration difference;

[0021] Obtain the pressure compensation value of the ventilator according to the carbon dioxide concentration difference and a preset linear relationship between carbon dioxide concentration and pressure.

[0022] In one embodiment, before the determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold, further includes:

[0023] Obtain the respiratory rate, carbon dioxide production and tidal volume of different types of people;

[0024] Calculate the corresponding carbon dioxide concentration reference value of different types of people according to the respiratory rate, the carbon dioxide production and the tidal volume;

[0025] Identify the population type corresponding to the current patient, and obtain a preset carbon dioxide concentration threshold according to the population type and the carbon dioxide concentration baseline values corresponding to different types of populations.

[0026] In one embodiment, the calculating the target tidal volume according to the target pressure value includes:

[0027] Obtain the lung compliance constant, airway resistance, and gas flow rate inside the ventilator;

[0028] Calculate the target tidal volume according to the target pressure value, the lung compliance constant, the airway resistance, and the gas flow rate inside the ventilator.

[0029] In a second aspect, the present application also provides a ventilator pressure and tidal volume adjustment device. The device includes:

[0030] A parameter acquisition module, configured to acquire the carbon dioxide concentration at the end of the patient's exhalation;

[0031] A pressure compensation module, configured to determine a pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold; acquire the real-time pressure of the ventilator, and obtain a target pressure value based on the pressure compensation value and the real-time pressure;

[0032] A tidal volume calculation module, configured to calculate a target tidal volume according to the target pressure value;

[0033] An adjustment module, configured to adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0034] In a third aspect, the present application also provides a computer device. The computer device includes a memory and a processor. The memory stores a computer program, and when the processor executes the computer program, the following steps are implemented:

[0035] Acquire the carbon dioxide concentration at the end of the patient's exhalation;

[0036] Determine a pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold;

[0037] Acquire the real-time pressure of the ventilator, and obtain a target pressure value based on the pressure compensation value and the real-time pressure;

[0038] Calculate the target tidal volume according to the target pressure value;

[0039] Adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0040] Fourth aspect, the present application also provides a computer-readable storage medium. On the computer-readable storage medium, there is a computer program stored, and when the computer program is executed by a processor, the following steps are implemented:

[0041] Obtain the carbon dioxide concentration at the end of the patient's exhalation;

[0042] Determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold;

[0043] Obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value;

[0044] Calculate the target tidal volume according to the target pressure value;

[0045] Adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0046] Fifth aspect, the present application also provides a computer program product. The computer program product includes a computer program, and when the computer program is executed by a processor, the following steps are implemented:

[0047] Obtain the carbon dioxide concentration at the end of the patient's exhalation;

[0048] Determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold;

[0049] Obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value;

[0050] Calculate the target tidal volume according to the target pressure value;

[0051] Adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0052] Sixth aspect, the present application also provides a ventilator, including a ventilator body and a controller. The controller is built into the ventilator body, and the controller adjusts the ventilator pressure and tidal volume by using the method as described above.

[0053] The above-mentioned ventilator pressure and tidal volume adjustment method, device, computer device, storage medium, and computer program product obtain the carbon dioxide concentration at the end of the patient's exhalation; determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold; obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value; calculate the target tidal volume according to the target pressure value; adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume. Throughout the process, the ventilator pressure and tidal volume are compensated / regulated based on the carbon dioxide concentration at the end of the patient's exhalation. The ventilator can continuously and stably provide appropriate pressure and tidal volume support according to the actual exhaled carbon dioxide concentration of the patient, realizing stable adjustment of the ventilator pressure and tidal volume. BRIEF DESCRIPTION OF THE DRAWINGS

[0054] Figure 1 FIG. is an application environment diagram of the ventilator pressure and tidal volume adjustment method in an embodiment;

[0055] Figure 2 FIG. is a flowchart of the ventilator pressure and tidal volume adjustment method in an embodiment;

[0056] Figure 3 FIG. is a flowchart of the ventilator pressure and tidal volume adjustment method in another embodiment;

[0057] Figure 4 FIG. is a structural block diagram of the ventilator pressure and tidal volume adjustment device in an embodiment;

[0058] Figure 5 FIG. is an internal structure diagram of a computer device in an embodiment. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0059] In order to make the objectives, technical solutions, and advantages of the present application clearer, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0060] The ventilator pressure and tidal volume adjustment method provided in the embodiments of the present application can be applied to an application environment as shown in Figure 1 FIG. After the ventilator is powered on and starts up, the controller built into the ventilator body obtains the carbon dioxide concentration at the end of the patient's exhalation; determines the pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold; obtains the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtains the target pressure value; calculates the target tidal volume according to the target pressure value; adjusts the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0061] In one embodiment, as shown in Figure 2As shown, a method for adjusting the pressure and tidal volume of a ventilator is provided. Taking the application of this method to the Figure 1 controller in it as an example for illustration, it includes the following steps:

[0062] S100: Obtain the carbon dioxide concentration at the end of the patient's exhalation.

[0063] Specifically, the carbon dioxide concentration at the end of the patient's exhalation can be obtained by calculation or sensor collection. If the calculation method is adopted, the carbon dioxide concentration at the end of the patient's exhalation can be obtained by analyzing the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation. If the sensor collection method is adopted, the carbon dioxide concentration at the end of the patient's exhalation can be directly collected by a carbon dioxide sensor.

[0064] S200: Determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold.

[0065] The controller stores a preset carbon dioxide concentration threshold range (usually 35 - 45 mmHg). Compare the measured carbon dioxide concentration with the upper threshold: when the concentration exceeds the upper threshold, it is determined that there is insufficient ventilation and a positive pressure compensation value is generated; when the concentration is lower than the lower threshold, it is determined that there is excessive ventilation and a negative pressure compensation value is generated. The size of the compensation value is determined by the proportional adjustment method according to the deviation amplitude, and the greater the deviation, the greater the absolute value of the compensation value.

[0066] S300: Obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value.

[0067] The dynamic pressure signal of the ventilator's air supply pipeline is collected in real time by a piezoelectric pressure sensor, and the sampling frequency is set to 100 Hz. After performing moving average filtering on the original pressure data, it is algebraically superimposed with the pressure compensation value obtained in S200. In specific implementation, the target pressure value = real-time pressure measurement value + pressure compensation value, forming a pressure closed-loop control reference.

[0068] S400: Calculate the target tidal volume according to the target pressure value.

[0069] Based on the respiratory mechanics model, the target tidal volume is positively correlated with the target pressure value. The controller calculates the target tidal volume through linear interpolation according to the preset lung compliance parameters (usually 30 - 50 mL / cmH2O) and airway resistance parameters. For special patient groups, individualized lung compliance parameters can be pre-input for adaptive calculation.

[0070] S500: Adjust the pressure and tidal volume of the ventilator based on the target pressure value and the target tidal volume.

[0071] Based on the target pressure value determined by S300 and the target tidal volume calculated by S400, the dynamic adjustment of the ventilator parameters is achieved through a closed-loop control algorithm. Among them, for pressure adjustment: the ventilator drive module adjusts the output pressure or flow rate of the drive gas source through a proportional-integral-derivative (PID) controller according to the difference between the target pressure value and the current actual pressure. For tidal volume adjustment: in the pressure control mode, the controller dynamically adjusts the inspiratory time or the pressure rise slope by real-time monitoring of the volume integral value under the flow curve to ensure that the deviation between the actually delivered tidal volume and the target value within a single breathing cycle does not exceed ±10%. In the volume control mode, the controller directly uses the target tidal volume as a reference and achieves precise control by adjusting the inspiratory pressure or the flow rate waveform (such as a square wave, a decelerating wave).

[0072] For the above-mentioned ventilator pressure and tidal volume adjustment method, obtain the carbon dioxide concentration at the end of the patient's exhalation; determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and the preset carbon dioxide concentration threshold; obtain the real-time pressure of the ventilator, and based on the pressure compensation value and the real-time pressure, obtain the target pressure value; calculate the target tidal volume according to the target pressure value; perform ventilator pressure and tidal volume adjustment based on the target pressure value and the target tidal volume. Throughout the process, the ventilator pressure and tidal volume are compensated / regulated based on the carbon dioxide concentration at the end of the patient's exhalation. The ventilator can continuously and stably provide appropriate pressure and tidal volume support according to the actual exhaled carbon dioxide concentration of the patient, realizing stable ventilator pressure and tidal volume adjustment.

[0073] In one of the embodiments, as Figure 3 shown, S100 includes:

[0074] S120: Obtain the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation respectively.

[0075] The oxygen concentration output by the oxygen generator ( , that is, the oxygen concentration of the gas inhaled by the patient) and the oxygen concentration of the exhaled gas at the end of the patient's exhalation ( ) are respectively collected in real time by a gas concentration sensor. The end of exhalation specifically refers to the gas sample within the last 300 ms of the expiratory phase, and the sampling is triggered by the timing controller of the ventilator expiratory branch.

[0076] S140: Calculate the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation.

[0077] Based on the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales obtained above, calculations are performed in combination with the principles of respiratory physiology. Specifically, during the breathing process, oxygen is inhaled by the patient and metabolically consumed in the body, while carbon dioxide is produced and exhaled out of the body. According to the gas exchange law, under the ideal gas state and ignoring the influence of other gas components, the carbon dioxide concentration at the end of the patient's exhalation is calculated.

[0078] In one embodiment, calculating the carbon dioxide concentration at the end of the patient's exhalation based on the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales includes:

[0079] Step 1: Calculate the carbon dioxide production and oxygen consumption based on the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales.

[0080] The oxygen concentration output by the oxygen generator and the oxygen concentration of the exhaled gas at the end of the patient's exhalation are respectively and real-time collected by high-precision gas sensors. The sampling time window at the end of exhalation is set to the last 300 ms of the expiratory phase, and sampling is triggered by the timing control module of the expiratory branch of the ventilator to ensure capturing alveolar gas samples. The oxygen consumption is determined as follows: Based on the volume of inhaled gas (measured by integrating the inspiratory flow sensor) and the volume of exhaled gas (measured by integrating the expiratory flow sensor), combined with the difference between the inhaled oxygen concentration and the exhaled oxygen concentration, calculate the net oxygen consumption per unit time. The carbon dioxide production is directly measured by the carbon dioxide metabolism monitoring module built into the ventilator or indirectly estimated through the associated parameters of a preset respiratory metabolism model.

[0081] Specifically, for inhaled gas: oxygen concentration , carbon dioxide concentration ; for exhaled gas: oxygen concentration , carbon dioxide concentration ; the formula for calculating oxygen consumption is: ; in this formula is the volume of inhaled gas, is the volume of exhaled gas; the formula for calculating carbon dioxide production is: .

[0082] Step 2: Calculate the respiratory quotient based on the carbon dioxide production and oxygen consumption.

[0083] Calculate the respiratory quotient (RQ) based on the oxygen consumption and carbon dioxide production, specifically the ratio of carbon dioxide production to oxygen consumption. The respiratory quotient reflects the patient's metabolic state and is used for subsequent dynamic correction of the carbon dioxide concentration. The formula for calculating the respiratory quotient is as follows:

[0084]

[0085] In the above formula, is the carbon dioxide production; is the oxygen consumption.

[0086] Step 3: Calculate the carbon dioxide concentration at the end of the patient's exhalation according to the respiratory quotient.

[0087] Based on the calculated respiratory quotient and oxygen consumption, combined with the gas volume at the end of exhalation (determined by integrating the flow rate in the last 300 ms of the expiratory phase), calculate the carbon dioxide concentration at the end of exhalation through a proportional relationship. Specifically, the carbon dioxide concentration value is the ratio of the carbon dioxide production to the exhaled gas volume, where the carbon dioxide production is indirectly obtained by multiplying the respiratory quotient by the oxygen consumption. Specifically, combined with the above formula, the carbon dioxide concentration calculation formula is as follows:

[0088] .

[0089] In one embodiment, determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold includes:

[0090] Step 1: Calculate the difference between the carbon dioxide concentration and the preset carbon dioxide concentration threshold to obtain the carbon dioxide concentration difference.

[0091] Obtain the carbon dioxide concentration value at the end of the patient's exhalation and compare it with the preset carbon dioxide concentration threshold range. Obtain the deviation amount between the current carbon dioxide concentration and the threshold through subtraction, that is, the carbon dioxide concentration difference. The threshold range is set according to clinical standards, such as 35 - 45 mmHg. Based on the carbon dioxide concentration difference, calculate the pressure compensation value according to a preset linear mapping relationship. Specifically, when the carbon dioxide concentration is higher than the upper threshold, it is determined that ventilation is insufficient, and a positive pressure compensation value (i.e., increasing the pressure) is generated; when the carbon dioxide concentration is lower than the lower threshold, it is determined that hyperventilation occurs, and a negative pressure compensation value (i.e., reducing the pressure) is generated. The absolute value of the compensation value is proportional to the magnitude of the carbon dioxide concentration difference, and the greater the deviation, the greater the compensation amplitude. The linear relationship is pre-configured through the ventilator control parameters. This parameter can be specifically obtained through calibration in the experimental state.

[0092] Step 2: Obtain the pressure compensation value of the ventilator according to the carbon dioxide concentration difference and the preset linear relationship between carbon dioxide concentration and pressure.

[0093] Superimpose the pressure compensation value on the real-time pressure measurement value of the ventilator to generate the target pressure value. Further according to the target pressure value.

[0094] In one embodiment, before determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold, it further includes:

[0095] Step 1: Obtain the respiratory rate, carbon dioxide production, and tidal volume of different types of people.

[0096] Obtain the respiratory parameters of different types of people (such as adults, children, patients with respiratory diseases) through the ventilator historical data storage module, including respiratory rate, carbon dioxide production, and tidal volume. The data is accumulated by long-term monitoring of the respiratory characteristics of patients at rest to ensure that it reflects the normal physiological state of individuals.

[0097] Step 2: Calculate the carbon dioxide concentration baseline value corresponding to different types of people based on the respiratory rate, carbon dioxide production, and tidal volume.

[0098] For each type of person, based on the mean values of their respiratory rate, carbon dioxide production, and tidal volume, calculate the corresponding carbon dioxide concentration baseline value through a linear regression model. A proportional coefficient and an intercept constant are introduced into the model to correlate the tidal volume with the carbon dioxide production and generate a baseline value that reflects the metabolic characteristics of the population. For example, the baseline value decreases as the tidal volume increases and increases as the carbon dioxide production increases.

[0099] Step 3: Identify the population type corresponding to the current patient, and obtain the preset carbon dioxide concentration threshold based on the population type and the carbon dioxide concentration baseline value corresponding to different types of people.

[0100] Determine the population type to which the current patient belongs through the patient-related parameters input through the patient information input interface. Call the pre-stored carbon dioxide concentration baseline value of this type of population and use it as the preset carbon dioxide concentration threshold.

[0101] In one embodiment, calculating the target tidal volume according to the target pressure value includes:

[0102] Step 1: Obtain the lung compliance constant, airway resistance, and gas flow rate inside the ventilator.

[0103] The controller calls the lung compliance constant (preset as a fixed value according to the patient population type) and the default value of airway resistance from the configuration parameters pre-stored in the ventilator. At the same time, the gas flow rate during the inspiratory phase is monitored in real time through the ventilator flow sensor.

[0104] Step 2: Calculate the target tidal volume according to the target pressure value, lung compliance constant, airway resistance, and gas flow rate inside the ventilator.

[0105] Based on the target pressure value, combined with the lung compliance constant, airway resistance, and real-time gas flow rate, the target tidal volume is calculated through a respiratory mechanics model. Specifically, the target pressure value has a positive correlation with the target tidal volume, and its correlation is dominated by the lung compliance constant, while the product of airway resistance and gas flow rate is used to correct the pressure loss caused by dynamic gas flow changes. For example, at the same pressure, patients with higher lung compliance correspond to a larger target tidal volume. Specifically, the entire calculation formula is as follows:

[0106]

[0107] In the formula, Vt is the target tidal volume; is the target pressure value; the lung compliance is a constant, the airway resistance is the default value of 1, and the flow rate is the detected gas flow rate inside the ventilator.

[0108] It should be understood that although the steps in the flowcharts involved in the above embodiments are shown in sequence according to the arrows, these steps are not necessarily executed in the order indicated by the arrows. Unless there is a clear description in this article, the execution of these steps has no strict order limit, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above embodiments may include multiple steps or multiple stages. These steps or stages are not necessarily executed at the same time, but can be executed at different times. The execution order of these steps or stages is not necessarily sequential, but can be executed alternately or in turn with at least a part of other steps or steps or stages in other steps.

[0109] Based on the same inventive concept, the embodiments of the present application also provide a ventilator pressure and tidal volume adjustment device for implementing the ventilator pressure and tidal volume adjustment method involved above. The implementation solutions provided by this device to solve problems are similar to the implementation solutions described in the above method. Therefore, the specific limitations in one or more embodiments of the ventilator pressure and tidal volume adjustment device provided below can refer to the limitations on the ventilator pressure and tidal volume adjustment method in the above text, and will not be repeated here.

[0110] In one embodiment, as Figure 4 shown, a ventilator pressure and tidal volume adjustment device is provided, including:

[0111] A parameter acquisition module 100, configured to acquire the carbon dioxide concentration at the end of the patient's exhalation;

[0112] A pressure compensation module 200, configured to determine the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold; acquire the real-time pressure of the ventilator, and obtain the target pressure value based on the pressure compensation value and the real-time pressure;

[0113] The tidal volume calculation module 300 is configured to calculate a target tidal volume according to a target pressure value;

[0114] The adjustment module 400 is configured to adjust the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

[0115] In one embodiment, the parameter acquisition module 100 is further configured to respectively acquire the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales; and calculate the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales.

[0116] In one embodiment, the parameter acquisition module 100 is further configured to calculate the carbon dioxide production amount and the oxygen consumption amount according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient exhales; calculate the respiratory quotient according to the carbon dioxide production amount and the oxygen consumption amount; and calculate the carbon dioxide concentration at the end of the patient's exhalation according to the respiratory quotient.

[0117] In one embodiment, the pressure compensation module 200 is further configured to calculate the difference between the carbon dioxide concentration and a preset carbon dioxide concentration threshold value to obtain a carbon dioxide concentration difference value; and obtain a pressure compensation value of the ventilator according to the carbon dioxide concentration difference value and a preset linear relationship between carbon dioxide concentration and pressure.

[0118] In one embodiment, the pressure compensation module 200 is further configured to acquire the respiratory frequency, carbon dioxide production amount, and tidal volume of different types of people; calculate a carbon dioxide concentration reference value corresponding to different types of people according to the respiratory frequency, carbon dioxide production amount, and tidal volume; identify the population type corresponding to the current patient, and obtain a preset carbon dioxide concentration threshold value according to the population type and the carbon dioxide concentration reference value corresponding to different types of people.

[0119] In one embodiment, the tidal volume calculation module 300 is further configured to acquire a lung compliance constant, airway resistance, and gas flow rate inside the ventilator; and calculate the target tidal volume according to the target pressure value, the lung compliance constant, the airway resistance, and the gas flow rate inside the ventilator.

[0120] Each module in the above ventilator pressure and tidal volume adjustment device can be implemented in whole or in part by software, hardware, and their combination. The above modules can be embedded in or independent of a processor in a computer device in the form of hardware, or stored in a memory in the computer device in the form of software, so as to facilitate the processor to call and execute the operations corresponding to the above respective modules.

[0121] In one embodiment, the present application further provides a ventilator, including a ventilator body and a controller. The controller is built into the ventilator body, and the controller adjusts the ventilator pressure and tidal volume by using the method as described above.

[0122] In one embodiment, a computer device is provided. The computer device may be a terminal, and its internal structural diagram may be as shown in Figure 5 . The computer device includes a processor, a memory, a communication interface, a display screen, and an input device connected through a system bus. Among them, the processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The communication interface of the computer device is used to communicate with an external terminal in a wired or wireless manner, and the wireless manner can be implemented through WIFI, a mobile cellular network, NFC (Near Field Communication), or other technologies. When the computer program is executed by the processor, it implements a method for adjusting the pressure and tidal volume of a ventilator. The display screen of the computer device may be a liquid crystal display screen or an electronic ink display screen. The input device of the computer device may be a touch layer covering the display screen, or a button, a trackball, or a touchpad provided on the housing of the computer device, or an external keyboard, touchpad, or mouse, etc.

[0123] Those skilled in the art can understand that Figure 5 the structure shown in is only a block diagram of some structures related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine some components, or have different component arrangements.

[0124] In one embodiment, a computer device is provided, including a memory and a processor. A computer program is stored in the memory, and when the processor executes the computer program, it implements the above-mentioned method for adjusting the pressure and tidal volume of a ventilator.

[0125] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by the processor, it implements the above-mentioned method for adjusting the pressure and tidal volume of a ventilator.

[0126] In one embodiment, a computer program product is provided, including a computer program. When the computer program is executed by the processor, it implements the above-mentioned method for adjusting the pressure and tidal volume of a ventilator.

[0127] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through a computer program. The computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above methods. Among them, any reference to a memory, database, or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memories. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetoresistive random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM), etc. The databases involved in the embodiments provided in the present application can include at least one of relational databases and non-relational databases. Non-relational databases can include distributed databases based on blockchain, etc., without limitation. The processors involved in the embodiments provided in the present application can be general-purpose processors, central processing units, graphics processing units, digital signal processors, programmable logic devices, data processing logics based on quantum computing, etc., without limitation.

[0128] The technical features of the above embodiments can be combined arbitrarily. For the sake of concise description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.

[0129] The above embodiments only represent several implementation manners of the present application. The description is relatively specific and detailed, but it should not be construed as a limitation on the patent scope of the present application. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present application, several modifications and improvements can be made, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims

1. A method for adjusting the pressure and tidal volume of a ventilator, characterized in that, The method includes: Obtaining the carbon dioxide concentration at the end of the patient's exhalation; Determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold; Obtaining the real-time pressure of the ventilator, and obtaining a target pressure value based on the pressure compensation value and the real-time pressure; Calculating a target tidal volume according to the target pressure value; Adjusting the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

2. The method according to claim 1, wherein Obtaining the carbon dioxide concentration at the end of the patient's exhalation includes: Respectively obtaining the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation; Calculating the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation.

3. The method according to claim 2, wherein The calculating the carbon dioxide concentration at the end of the patient's exhalation according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation includes: Calculating the carbon dioxide production amount and the oxygen consumption amount according to the oxygen concentration output by the oxygen generator and the oxygen concentration after the patient's exhalation; Calculating the respiratory quotient according to the carbon dioxide production amount and the oxygen consumption amount; Calculating the carbon dioxide concentration at the end of the patient's exhalation according to the respiratory quotient.

4. The method according to claim 1, characterized in that The determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold includes: Calculating the difference between the carbon dioxide concentration and the preset carbon dioxide concentration threshold to obtain a carbon dioxide concentration difference; Obtaining the pressure compensation value of the ventilator according to the carbon dioxide concentration difference and a preset linear relationship between carbon dioxide concentration and pressure.

5. The method according to claim 1, characterized in that Before the determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold, it further includes: Obtaining the respiratory frequency, carbon dioxide production amount, and tidal volume of different types of people; Calculating the corresponding carbon dioxide concentration reference value for different types of people according to the respiratory frequency, the carbon dioxide production amount, and the tidal volume; Identifying the population type corresponding to the current patient, and obtaining a preset carbon dioxide concentration threshold according to the population type and the corresponding carbon dioxide concentration reference value for different types of people.

6. The method according to claim 1, wherein The calculating a target tidal volume according to the target pressure value includes: Obtaining the lung compliance constant, airway resistance, and gas flow rate inside the ventilator; Calculating the target tidal volume according to the target pressure value, the lung compliance constant, the airway resistance, and the gas flow rate inside the ventilator.

7. A ventilator pressure and tidal volume adjustment device, characterized in that, The device includes: A parameter acquisition module for obtaining the carbon dioxide concentration at the end of the patient's exhalation; A pressure compensation module for determining the pressure compensation value of the ventilator according to the carbon dioxide concentration and a preset carbon dioxide concentration threshold; obtaining the real-time pressure of the ventilator, and obtaining a target pressure value based on the pressure compensation value and the real-time pressure; A tidal volume calculation module for calculating a target tidal volume according to the target pressure value; An adjustment module for adjusting the ventilator pressure and tidal volume based on the target pressure value and the target tidal volume.

8. A computer device, comprising a memory and a processor, the memory storing a computer program, characterized in that, When the processor executes the computer program, it implements the steps of the method according to any one of claims 1 to 6.

9. A computer-readable storage medium having a computer program stored thereon, characterized in that, When the computer program is executed by a processor, it implements the steps of the method according to any one of claims 1 to 6.

10. A ventilator, characterized in that, It includes a ventilator body and a controller. The controller is built into the ventilator body, and the controller adjusts the ventilator pressure and tidal volume by using the method according to any one of claims 1 to 6.

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