Multi-band adjustable skin penetrating light source system and control method

Abstract

The invention relates to the technical field of biomedical optics, in particular to a multiband adjustable skin penetrating light source system and a control method, and the technical scheme is characterized in that the multiband adjustable skin penetrating light source system comprises a sub-band light source array covering 380-980 nm and supporting multichannel independent control; the dynamic control module is integrated with the FPGA and the thermoelectric refrigeration module; and the optical coupling module comprises an image transmitting optical fiber and an aspheric collimating lens. On the basis of an existing light source system, through adjustment and combination and through modular collaborative design, full-link optimization from light source control to light beam transmission is achieved, the flexibility, precision and stability of the system are remarkably improved, and a high-performance solution is provided for the fields of spectral analysis and biomedicine.

Description

Technical Field

[0001] The present invention relates to the technical field of biomedical optics, and specifically relates to a multi-band adjustable skin penetration light source system and a control method thereof. Background Art

[0002] Traditional skin detection light sources adopt fixed band combinations and cannot be dynamically adjusted according to the detection depth (for example, 380 - 600 nm is required for the epidermis layer, and 700 - 980 nm is required for the dermis layer); wide-spectrum illumination results in energy waste, and the excitation efficiency of key biomarkers (such as hemoglobin and melanin) is low.

[0003] Phototherapy instruments mainly include three parts: a phototherapy light source, an optical structure, and a hardware circuit. LEDs gradually replace low-intensity lasers in the application of photobiomodulation and large-area photodynamic therapy due to their unique advantages such as long lifespan, light weight, safety, environmental friendliness, and convenient control.

[0004] The penetration depths of different wavelengths in the skin are also different. In some cases, combinations of different wavelengths can enhance the treatment effect. For example, in the treatment of acne, the porphyrin photodynamic effect of blue light is the main one. The photodynamic effect of red light on porphyrin is weaker than that of blue light, but its wavelength is longer, so it can act on deeper sebaceous glands, regulate pathways such as mitochondria, play an anti-inflammatory role, and accelerate metabolism. The phototherapy for acne can be divided into two treatment methods: simply irradiating with blue light and red light, and treating with external photosensitizers combined with blue light and red light.

[0005] Through the investigation of the characteristics and functions of current LED skin phototherapy instruments, it is found that there are the following deficiencies: only wavelengths can be selected, the intensity is not adjustable; there are few combination modes; the power is relatively low; there are few adjustable parameters; the operation is inconvenient, etc. Summary of the Invention

[0006] In order to solve the technical problems and disadvantages in the prior art, the present invention provides a multi-band adjustable skin penetration light source system and a control method thereof, which can achieve adaptive adjustment of the skin penetration depth through wavelength-intensity collaborative control.

[0007] To achieve the above object and other related objects, the present invention adopts the following technical solutions:

[0008] A multi-band adjustable skin penetration light source system includes:

[0009] A sub-band light source array that covers 380 - 980 nm and supports multi-channel independent control;

[0010] A dynamic control module that integrates an FPGA and a thermoelectric cooling module;

[0011] An optical coupling module that includes an image transmission optical fiber and an aspherical collimating lens.

[0012] Preferably, the multi-band light source array is composed of two integrated LED chips. Each LED chip internally contains at least a 10×10 LED array group. The LED array group is integrated on a chip substrate with a size of at least 20mm×20mm. Multiple LED chips are designed with a certain spacing and angle, and through the converging effect of lenses and reflectors, the light spots on the illumination plane are basically overlapped.

[0013] Preferably, the multi-band light source array is 20 cm away from the irradiation area. According to the size parameters of the LED lamp beads, a 4×10 blue LED lamp bead array, a 2×10 yellow LED lamp bead array, and a 4×10 red LED lamp bead array are formed.

[0014] Preferably, it further includes an input / output module, a clock module, a reset module, a negative oxygen generation module, a heat dissipation module, a single-chip microcomputer module, a power supply module, a red LED driver module, a blue LED driver module, a yellow LED driver module, and an LED chip. The LED chip has three interfaces for red, blue, and yellow, which are respectively connected to the red LED driver module, the blue LED driver module, and the yellow LED driver module. The red LED driver module, the blue LED driver module, and the yellow LED driver module are all connected to the single-chip microcomputer module and controlled by it. The power supply module provides working power for the single-chip microcomputer module, the red LED driver module, the blue LED driver module, and the yellow LED driver module. The heat dissipation module is connected to the single-chip microcomputer module and controlled by it to provide heat dissipation for it;

[0015] The single-chip microcomputer module is also connected to the input / output module for human-computer interaction, connected to the clock module for obtaining the working clock and signal alignment, connected to the reset module for program reset, and connected to the negative oxygen generation module.

[0016] Preferably, the red LED driver module, the blue LED driver module, and the yellow LED driver module have the same structure and all include a communication interface module, a microprocessor module, a digital-to-analog conversion module, an operational amplifier module, a load interface, a current detection and amplification module, and an analog-to-digital conversion module. The communication interface module is connected to the microprocessor module to provide communication signals. The microprocessor module, the analog-to-digital conversion module, the operational amplifier module, the load interface, the current detection and amplification module, and the analog-to-digital conversion module are connected in sequence to form a closed loop.

[0017] Preferably, the microprocessor module is also connected to a dimming switch, and the current detection and amplification module is connected to a current display module.

[0018] Preferably, the multi-band light source array is divided into three groups: UV-Vis group, Vis-NIR group, and NIR group. The UV-Vis group uses a wavelength range of 380 - 600 nm and employs 4 LED lamp beads with a peak power of 50 mW;

[0019] The Vis-NIR group uses a wavelength range of 600 - 850 nm and employs 2 laser diodes;

[0020] The NIR group uses a wavelength range of 850 - 980 nm, employs 2 VCSEL arrays, the adjustable range of the output power is 0 - 200 mW, and a graphene heat spreader is provided on the thermoelectric cooling module.

[0021] Preferably, the dynamic control module operates in the following modes:

[0022] Epidermal layer mode: Activate the 380 - 500 nm band, with a weight ratio of 70%;

[0023] Dermal layer mode: Activate the 780 - 980 nm band, with a weight ratio of 80%;

[0024] Hybrid mode: Automatically allocate wavelength energy according to the detection target.

[0025] In addition, a multi - band adjustable skin penetration light source control method is also provided. According to the above - mentioned multi - band adjustable skin penetration light source system, calculate the effective penetration depth of each wavelength based on the skin optical model; dynamically allocate the band energy weight according to the detection target; and adjust the light source output power in real time through the hyperspectral feedback signal.

[0026] Preferably, during epidermal layer analysis, the total energy ratio of the 380 - 500 nm band is ≥70%; during dermal layer analysis, the total energy ratio of the 780 - 980 nm band is ≥80%; the hybrid mode supports user - defined wavelength combinations.

[0027] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0028] 1. The present invention realizes wide - spectrum coverage and independent control through a multi - band light source array. The dynamic control module can respond in real time and has stable temperature control, and the optical coupling module has the characteristics of high coupling efficiency and beam optimization, so as to provide a reliable multi - band adjustable skin penetration light source.

[0029] 2. This solution realizes the full - link optimization from light source control to beam transmission through modular collaborative design, significantly improving the flexibility, precision and stability of the system, and providing a high - performance solution for the fields of spectral analysis and biomedicine.

[0030] Other additional advantages and beneficial effects of this application will be partially given in the following description, partially will become obvious from the following description, or will be understood through the practice of this application. Brief Description of the Drawings

[0031] The accompanying drawings are used to provide a further understanding of the present invention and form a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention. In the drawings:

[0032] Figure 1 is an overall schematic diagram of the light source LED chip arrangement in Embodiment 1 of the present application;

[0033] Figure 2 is a schematic diagram of the layout of the lamp beads inside the LED chip in Embodiment 1 of the present application;

[0034] Figure 3 is a schematic diagram of the circuit principle in Embodiment 1 of the present application;

[0035] Figure 4 is a schematic diagram of the circuit principle of the LED driving module in Embodiment 1 of the present application.

[0036] Explanation of the reference numerals of the main components:

[0037] 100, input / output module; 200, clock module; 300, reset module; 400, negative oxygen generation module; 500, heat dissipation module; 600, single-chip microcomputer module; 700, power supply module; 801, red LED driving module; 802, blue LED driving module; 803, yellow LED driving module; 900, LED chip; 811, communication interface module; 812, microprocessor module; 813, digital-to-analog conversion module; 814, operational amplifier module; 815, load interface; 816, current detection and amplification module; 817, analog-to-digital conversion module; 818, dimming switch; 819, current display module. Specific Embodiments

[0038] The following further describes the specific embodiments of the present invention in conjunction with the accompanying drawings. The following specific examples illustrate the embodiments of the present invention. Those skilled in the art can easily understand the other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments. Various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that, without conflict, the following embodiments and the features in the embodiments can be combined with each other.

[0039] It should be noted that the diagrams provided in the following embodiments only illustrate the basic concept of the present invention in a schematic manner. The diagrams only show the components related to the present invention rather than being drawn according to the number, shape, and size of the components in actual implementation. The type, quantity, and ratio of each component in actual implementation can be changed arbitrarily, and the component layout type may also be more complex.

[0040] It should be noted that in the description of this application, the terms indicating the direction or positional relationship such as "upper", "lower", "left", "right", "inner", "outer", etc. are based on the direction or positional relationship shown in the drawings. This is only for convenience of description, rather than indicating or implying that the device or element must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present invention. In addition, it should also be noted that in the description of this application, unless otherwise clearly specified and limited, the terms "installation", "connection", "coupling", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0041] Embodiment 1:

[0042] An embodiment of the present invention discloses a multi-band adjustable skin-penetrating light source system, including a multi-band light source array covering 380 - 980 nm and supporting multi-channel independent control; a dynamic control module integrating an FPGA and a thermoelectric cooling module; and an optical coupling module including an image transmission optical fiber and an aspherical collimating lens.

[0043] In a specific case, referring to Figure 1 as shown, the multi-band light source array is two integrated LED chips 900. Referring to Figure 2 as shown, each LED chip 900 internally includes at least a 10×10 LED array group. The LED array group is integrated on a chip substrate with a size of at least 20 mm×20 mm. Multiple LED chips 900 are designed with a certain distance and angle, and by using the converging effect of the lens and the reflector cup, the light spots on the irradiation plane are basically overlapped.

[0044] In Figure 2 it can be seen that the multi-band light source array is 20 cm away from the irradiation area. According to the size parameters of the LED lamp beads, a 4×10 blue LED lamp bead array, a 2×10 yellow LED lamp bead array, and a 4×10 red LED lamp bead array are formed. And by using the converging effect of the lens and the reflector cup, the light spots on the irradiation plane are basically overlapped, increasing the irradiance received by the irradiation surface and making the illumination of the irradiation area uniform. Based on the comfort level felt by people, the light source is set at a distance of 20 cm from the irradiation area, which can completely cover the human face. The center distance between the two LED chips 900 is set to 17 cm. Therefore, by adjusting the angle α between the two LED array light sources, the irradiance distribution of the receiving surface can be adjusted. While making the light spots overlap, the light intensity of the irradiated area is relatively uniform. When α = 154.6°, the uniformity is the best.

[0045] Reference Figure 3 and Figure 4 Understanding also includes an input / output module 100, a clock module 200, a reset module 300, a negative oxygen generation module 400, a heat dissipation module 500, a single-chip microcomputer module 600, a power supply module 700, a red LED driving module 801, a blue LED driving module 802, a yellow LED driving module 803, and an LED chip 900. The LED chip 900 has three interfaces for red, blue, and yellow, and is correspondingly connected to the red LED driving module 801, the blue LED driving module 802, and the yellow LED driving module 803. The red LED driving module 801, the blue LED driving module 802, and the yellow LED driving module 803 are all connected to the single-chip microcomputer module 600 and are controlled by it. Since the electrical parameters required for the three types of light are different, three independent LED driving modules are used to control the output voltage and current. The power supply module 700 provides the working power supply for the single-chip microcomputer module 600, the red LED driving module 801, the blue LED driving module 802, and the yellow LED driving module 803. The heat dissipation module 500 is connected to the single-chip microcomputer module 600 and is controlled by it to provide heat dissipation. The operating voltage range of the driving circuit is 20 - 36V, and the maximum current of a single path is 2400mA. The power supply module 700 selects a switching power supply to solve the electromagnetic compatibility problem.

[0046] The single-chip microcomputer module 600 is also connected to the input / output module 100 for human-machine interaction, connected to the clock module 200 for obtaining the working clock and signal alignment, connected to the reset module 300 for program reset, and connected to the negative oxygen generation module 400. The negative oxygen generation module 400 is controlled by the single-chip microcomputer module 600 to release negative oxygen ions or not.

[0047] Reference Figure 4 As shown, the red LED driving module 801, the blue LED driving module 802, and the yellow LED driving module 803 have the same structure and all include a communication interface module 811, a microprocessor module 812, a digital-to-analog conversion module 813, an operational amplifier module 814, a load interface 815, a current detection and amplification module 816, and an analog-to-digital conversion module 817. The communication interface module 811 is connected to the microprocessor module 812 to provide communication signals. The microprocessor module 812, the analog-to-digital conversion module 817, the operational amplifier module 814, the load interface 815, the current detection and amplification module 816, and the analog-to-digital conversion module 817 are connected in sequence to form a closed loop. The microprocessor module 812 is also connected to a dimming switch 818, and the current detection and amplification module 816 is connected to a current display module 819.

[0048] A constant current circuit based on a linear power supply is usually a voltage-controlled current source. The digital-to-analog conversion module 813 and the operational amplifier module 814 are cascaded. Through the feedback loop composed of the microprocessor module 812, the current detection and amplification module 816, and the analog-to-digital conversion module 817, the output voltage of the operational amplifier is adjusted to control the load current, thus forming a numerically controlled voltage-controlled constant current source. The load interface 815 here is the interface connecting the LED chip 900. The load is the LED chip 900.

[0049] Embodiment 2:

[0050] Another solution can also be provided. The multi-band light source array is divided into three groups: the UV-Vis group, the Vis-NIR group, and the NIR group. The UV-Vis group uses a wavelength range of 380 - 600 nm and employs 4 high-color-rendering LED beads (peak 50 mW) to cover the ultraviolet-visible light band. This band has a strong ability to penetrate the epidermal layer (about 0.1 - 0.5 mm), can stimulate the activity of melanocytes, and is suitable for surface pigment regulation.

[0051] The Vis-NIR group uses a wavelength range of 600 - 850 nm and is configured with 2 semiconductor laser diodes (LDs). The output wavelength can be tuned to the hemoglobin absorption peak (760 nm) and the water absorption valley (808 nm), which is suitable for dermal vascular targeting.

[0052] Integrate 2 groups of vertical cavity surface emitting laser (VCSEL) arrays, supporting a continuously adjustable output of 0 - 200 mW. This band can penetrate to the subcutaneous 3 - 5 mm fat layer to activate mitochondrial metabolism. A graphene heat spreader is set on the thermoelectric cooling module. This solution adopts a three-level collaborative light source architecture to achieve targeted regulation of spectral energy through precise band division.

[0053] The dynamic control module operates in the following mode:

[0054] Epidermal layer mode: Activate the 380 - 500 nm band, with a weight ratio of 70%; 70% of the energy is concentrated in the 415 nm (blue light) and 470 nm (cyan light) bands. The photosensitization reaction of porphyrin is used to inhibit Propionibacterium acnes. During acne treatment, the system detects the inflammatory skin lesion area through a dermatoscope and automatically adjusts the spot shape (minimum diameter 0.5 mm) for precise irradiation.

[0055] Dermal layer mode: Activate the 780 - 980 nm band, with a weight ratio of 80%; 80% of the power is distributed to 850 nm (penetration depth 4 mm) and 915 nm (penetration depth 5 mm) to form a "photo-thermal superposition effect". In scar repair, this mode can raise the temperature of the dermal layer to 42 °C (within the safety threshold), promoting a 60% increase in the proliferation rate of fibroblasts.

[0056] Hybrid mode: Automatically allocate wavelength energy according to the detection target. Built-in spectral database to match the characteristics of the detection target (such as the type of skin pigmentation, blood vessel diameter, etc.). When dealing with mixed skin pigmentation, the system automatically allocates 45% of the energy for each of 630nm (inhibiting melanin production) and 940nm (accelerating metabolism), and the remaining 10% is used for 590nm (improving skin flushing).

[0057] Example 3:

[0058] A multi-band adjustable skin penetration light source control method. According to the above multi-band adjustable skin penetration light source system, calculate the effective penetration depth of each wavelength based on the skin optical model; dynamically allocate the band energy weight according to the detection target; and adjust the light source output power in real time through the hyperspectral feedback signal.

[0059] Preferably, when analyzing the epidermis layer, the total energy ratio of the 380 - 500nm band is ≥70%; when analyzing the dermis layer, the total energy ratio of the 780 - 980nm band is ≥80%; the hybrid mode supports user-defined wavelength combinations.

[0060] The present invention realizes wide spectral coverage and independent control through a multi-band light source array. The dynamic control module can respond in real time and has stable temperature control. The optical coupling module has the characteristics of high coupling efficiency and beam optimization, so as to provide a reliable multi-band adjustable skin penetration light source. Through modular collaborative design, this solution realizes the full-link optimization from light source control to beam transmission, significantly improving the flexibility, precision and stability of the system, and providing a high-performance solution for the fields of spectral analysis and biomedicine.

[0061] So far, the technical solution of the present invention has been described in conjunction with the preferred embodiments shown in the accompanying drawings. The above are only the preferred embodiments of the present invention and are not used to limit the present invention; for those skilled in the art, various changes and modifications can be made to the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A multi-band adjustable skin penetration light source system, characterized in that, including a band - split light source array, covering 380 - 980 nm and supporting multi - channel independent control a dynamic control module, integrating an FPGA and a thermoelectric cooling module an optical coupling module, including an image - transmitting optical fiber and an aspherical collimating lens 2. The multi-band adjustable skin penetration light source system according to claim 1, characterized in that, The band - split light source array is two integrated LED chips (900). Each LED chip (900) internally contains at least a 10×10 LED array group. The LED array group is integrated on a chip substrate with a size of at least 20 mm×20 mm. Multiple LED chips (900) are designed with a certain spacing and angle, and by using the converging effect of lenses and reflectors, the light spots on the irradiation plane are basically coincident.

3. The multi-band adjustable skin penetration light source system according to claim 2, characterized in that The band - split light source array is 20 cm away from the irradiation area. According to the size parameters of the LED lamp beads, a 4×10 blue - light lamp - bead array, a 2×10 yellow - light lamp - bead array, and a 4×10 red - light lamp - bead array are formed.

4. The multi-band adjustable skin penetration light source system according to claim 1, characterized in that, It also includes an input - output module (100), a clock module (200), a reset module (300), a negative - oxygen generation module (400), a heat - dissipation module (500), a single - chip microcomputer module (600), a power - supply module (700), a red - light LED driving module (801), a blue - light LED driving module (802), a yellow - light LED driving module (803), and an LED chip (900). The LED chip (900) has three interfaces for red, blue, and yellow, and correspondingly connects to the red - light LED driving module (801), the blue - light LED driving module (802), and the yellow - light LED driving module (803). The red - light LED driving module (801), the blue - light LED driving module (802), and the yellow - light LED driving module (803) are all connected to the single - chip microcomputer module (600) and are controlled by it. The power - supply module (700) provides the working power for the single - chip microcomputer module (600), the red - light LED driving module (801), the blue - light LED driving module (802), and the yellow - light LED driving module (803). The heat - dissipation module (500) is connected to the single - chip microcomputer module (600), is controlled by it, and provides heat dissipation for it. The single - chip microcomputer module (600) is also connected to the input - output module (100) for human - machine interaction, connected to the clock module (200) for obtaining the working clock and signal alignment, connected to the reset module (300) for program reset, and connected to the negative - oxygen generation module (400).

5. The multi-band adjustable skin penetration light source system according to claim 4, characterized in that, The red LED driving module (801), blue LED driving module (802), and yellow LED driving module (803) have the same structure and all include a communication interface module (811), a microprocessor module (812), a digital-to-analog conversion module (813), an operational amplifier module (814), a load interface (815), a current detection and amplification module (816), and an analog-to-digital conversion module (817). The communication interface module (811) is connected to the microprocessor module (812) to provide communication signals. The microprocessor module (812), analog-to-digital conversion module (817), operational amplifier module (814), load interface (815), current detection and amplification module (816), and analog-to-digital conversion module (817) are connected in sequence to form a closed loop.

6. The multi-band adjustable skin penetration light source system according to claim 1, characterized in that, The microprocessor module (812) is also connected to a dimming switch (818), and the current detection and amplification module (816) is connected to a current display module (819).

7. The multi-band adjustable skin penetration light source system according to claim 1, characterized in that The banded light source array is divided into three groups: the UV-Vis group, the Vis-NIR group, and the NIR group. The UV-Vis group uses a wavelength range of 380 - 600 nm, with 4 LED beads and a peak power of 50 mW. The Vis-NIR group uses a wavelength range of 600 - 850 nm and has 2 laser diodes. The NIR group uses a wavelength range of 850 - 980 nm, with 2 VCSEL arrays. The adjustable range of the output power is 0 - 200 mW, and a graphene heat spreader is provided on the thermoelectric cooling module.

8. The multi-band adjustable skin penetration light source system according to claim 7, characterized in that, The dynamic control module operates in the following modes: Epidermal layer mode: Activate the 380 - 500 nm band, with a weight ratio of 70%. Dermal layer mode: Activate the 780 - 980 nm band, with a weight ratio of 80%. Hybrid mode: Automatically allocate wavelength energy according to the detection target.

9. A multi-band adjustable skin penetration light source control method, according to the multi-band adjustable skin penetration light source system described in any one of claims 1-8, characterized in that, Calculate the effective penetration depth of each wavelength based on the skin optical model; Dynamically allocate the band energy weight according to the detection target; Real-time adjust the light source output power through the hyperspectral feedback signal.

10. The multi-band adjustable skin penetration light source control method according to claim 9, wherein During epidermal layer analysis, the total energy ratio of the 380 - 500 nm band is ≥70%; During dermal layer analysis, the total energy ratio of the 780 - 980 nm band is ≥80%; The hybrid mode supports user-defined wavelength combinations.

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