Feed capable of improving organism immunity of poultry and feeding method

Through the combination of basic feed, microecological regulators and immune nutrition enhancers, combined with real-time monitoring and dynamic adjustment, the problem of lack of dynamic regulation of poultry feed formulas in the existing technology has been solved, and precise nutrition intervention has been achieved to improve poultry immunity and health status.

CN120391580APending Publication Date: 2025-08-01QINGDAO ANIMAL HUSBANDRY WORKSTATION (QINGDAO ANIMAL HUSBANDRY & VETERINARY RES INST)
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Patent Information

Application Number
CN202510757311.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-09
Publication Date
2025-08-01

AI Technical Summary

Technical Problem

The existing feed formula lacks dynamic regulatory strategies, making it difficult to accurately identify the immune needs of poultry at different growth stages, resulting in nutrition waste or immune burden, and failing to systematically integrate feeding behaviors with poultry immunity indicators and environmental parameters, affecting poultry health.

Method used

The combination of basic feed components, microecological precision regulators and immune nutrition enhancers is adopted, combined with real-time monitoring of poultry feeding behavior and poultry house environmental parameters, dynamically adjust the proportion of each component, predict immune status and risk grading through machine learning algorithms, and implement precise nutrition intervention.

Benefits of technology

A breakthrough in nutritional intervention from static to precise has been achieved, maintaining the balance of intestinal flora, enhancing the immune function of avians, reducing the impact of environmental stress, and improving the targeted and stable immune regulation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a feed capable of improving the organism immunity of poultry and a feeding method, and relates to the technical field of poultry feeding, the feed comprises 85-90 parts of a basal feed component, 4-6 parts of a micro-ecological precise regulating agent and 4-6 parts of an immune nutrition enhancer, and the basal feed component is prepared from 85-90 parts of a basal feed component, 4-6 parts of a micro-ecological precise regulating agent and 4-6 parts of an immune nutrition enhancer; the basal feed comprises the following components in parts by weight: 60-65 parts of corn, 20-25 parts of soybean meal, 2-5 parts of wheat bran, 1-3 parts of fish meal and 1-2 parts of premix; the micro-ecological regulating agent is prepared from 2.5 to 3.5 parts of probiotics and 1.0 to 2.5 parts of prebiotics, and the immune nutrition enhancer is prepared from 1.5 to 2.5 parts of natural polyphenol, 1.5 to 2.5 parts of polysaccharide and 1.0 to 1.5 parts of amino acid. The invention has the following beneficial effects: accurate nutrition intervention can be realized, immune regulation effect can be significantly improved, and environmental stress influence can be reduced.
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Description

Technical Field

[0001] The present invention relates to the technical field of poultry breeding, and particularly to a feed and a breeding method capable of improving the immunity of poultry. Background Art

[0002] With the rapid development of the livestock and poultry breeding industry, poultry products occupy an increasingly important proportion in global meat consumption. In order to improve the production performance and economic benefits of poultry, improving their body immunity, reducing the incidence of diseases, and reducing the dependence on antibiotics have become one of the key issues urgently needed to be solved in the breeding industry. As a green and sustainable immune regulation method, nutritional intervention has received great attention in recent years. Especially, the introduction of functional nutrients and probiotics into the feed formula has a significant effect on improving the health status of poultry.

[0003] At present, some research and products have tried to regulate the balance of intestinal flora and enhance immune function by adding active substances such as probiotics, plant extracts, and polysaccharide compounds to the feed. For example, single components such as lactic acid bacteria probiotics, oligosaccharide prebiotics, tea polyphenols, or ganoderma lucidum polysaccharides are used for functional supplementation, or formula combinations are designed based on experience for feeding. However, most formulas are still mainly statically designed in fixed proportions, lacking dynamic regulation strategies, and lacking support and mechanisms in the evaluation of poultry immune status and precise nutritional intervention.

[0004] At the same time, the existing feeding methods lack precise identification and differential supply of the immune needs of poultry at different growth stages, which easily leads to nutritional waste or increased immune burden, and fail to systematically integrate and analyze feeding behaviors, poultry immune indicators, and poultry house environmental parameters, making it difficult to form targeted nutritional intervention strategies.

[0005] How to solve the above technical problems is the subject faced by the present invention. Summary of the Invention

[0006] In order to solve the deficiencies of the prior art, the present invention provides a feed and a breeding method capable of improving the immunity of poultry, which can achieve precise nutritional intervention, significantly improve the immune regulation effect, and reduce the impact of environmental stress.

[0007] The technical solution adopted by the present invention to solve its technical problems is: the present invention provides a feed capable of improving the immunity of poultry, including a basic feed component, a probiotic precise regulator, and an immune nutrition enhancer, wherein the basic feed component is 85-90 parts, the probiotic precise regulator is 4-6 parts, and the immune nutrition enhancer is 4-6 parts; The basic feed component includes 60-65 parts of corn, 20-25 parts of soybean meal, 2-5 parts of wheat bran, 1-3 parts of fish meal, and 1-2 parts of premix; The microecological regulator includes 2.5 - 3.5 parts of probiotics and 1.0 - 2.5 parts of prebiotics. The probiotics in the microecological regulator are selected from one or more of the genera Lactobacillus, Bifidobacterium, and Bacillus. The prebiotics in the microecological regulator are one or more of fructooligosaccharides and galactooligosaccharides.

[0008] The immune nutrition enhancer includes 1.5 - 2.5 parts of natural polyphenols, 1.5 - 2.5 parts of polysaccharides, and 1.0 - 1.5 parts of amino acids. The natural polyphenols in the immune nutrition enhancer are selected from one or more of tea polyphenols, grape seed extract, rosemary extract, or pomegranate polyphenols. The polysaccharide components in the immune nutrition enhancer include one or more of ganoderma lucidum polysaccharide, lentinan, or astragalus polysaccharide. The amino acids in the immune nutrition enhancer are one or more of arginine, glutamine, and cysteine.

[0009] A feeding method for a feed that can improve the immunity of poultry includes the following steps: S1. According to the breed, age, and weight of the poultry, determine its growth stage. For example, for fast-growing broilers (such as white - feather chickens): it is divided into the chick stage (1 - 21 days) and the growth stage (22 - 42 days). For local breeds (such as yellow - feather chickens): it is divided into the young poultry stage (1 - 28 days) and the fattening stage (29 - 56 days). In the chick stage: when <500g, increase the immune enhancer; in the fattening stage: when >2kg, reduce the basic feed and increase the microecological agent. S2. Record the feeding behavior data of the poultry. For example, when the daily feed intake drops by 15%, immediately add glutamine + prebiotics; when the feeding duration is >2h for 3 consecutive days, reduce wheat bran and increase fructooligosaccharides; when the feeding frequency fluctuates abnormally, increase the dosage of Bifidobacterium. S3. Monitor the changes in immune - related indicators of the poultry and poultry house environmental parameters. The immune - related indicators include serum immunoglobulin levels, intestinal flora diversity, and inflammatory factor expression levels, which are regularly sampled and analyzed through a data acquisition system. The poultry house environmental parameters include ammonia concentration, carbon dioxide concentration, suspended particulate matter concentration, water - borne microbial content, and bacterial population in the bedding. For example, when IgG <5mg / ml, increase the immune enhancer; when IgA <2mg / ml, adjust the proportion of Lactobacillus in the probiotics to 70%; when Escherichia coli is detected, completely replace the current probiotics with Bacillus; when the proportion of Bifidobacterium <10%, add galactooligosaccharides. For example, when ammonia >20ppm in the poultry house environmental parameters, reduce the basic feed and increase the probiotics; when CO2 >3000ppm, add tea polyphenols for anti - stress; when the coliform bacteria in the water exceed the standard, completely replace the polysaccharides in the immune enhancer with astragalus polysaccharide. S4. Dynamically adjust the addition ratios of the basal feed, microecological regulator, and immune nutrition enhancer in the feed according to the records and monitoring results of S1 - S3, and implement the feed - environment linkage regulation measures. The adjustment of the dynamic formula is based on the establishment of an immune response evaluation model, and the batching is carried out through the feedback results of the model. The model comprehensively inputs the poultry immune - related indicators, feeding behavior data, and poultry house environment parameters, and dynamically predicts the immune status and conducts risk grading through machine learning algorithms. The feedback results are used to adjust the feed nutrition ratio and additive level.

[0010] The beneficial effects of the present invention are as follows: By scientifically formulating the basal feed, microecological regulator, and immune nutrition enhancer, and based on the growth stage characteristics such as poultry breed, age, and weight, combined with the real - time monitored feeding behavior data, immune indicators, and poultry house environment parameters, the present invention dynamically adjusts the proportion of each component, achieving a breakthrough from static feeding to precise nutritional intervention, effectively solving the problems of fixed formula and lagging adjustment in the prior art. While maintaining the balance of intestinal flora and enhancing immune function, it significantly reduces the impact of environmental stress on poultry health, making the immune regulation more targeted and stable. Brief Description of the Drawings

[0011] Figure 1 It is a step diagram of the feeding method of the present invention. Detailed Embodiments

[0012] In order to clearly illustrate the technical features of the present solution, the present solution will be described below through specific embodiments.

[0013] Embodiment 1 Refer to Figure 1 As shown, this embodiment is a feed that can improve the immunity of poultry, including 89 parts of basal feed components, 5 parts of microecological precise regulator, and 6 parts of immune nutrition enhancer; The basal feed components include: 60 parts of corn, 22 parts of soybean meal, 3 parts of wheat bran, 2 parts of fish meal, and 1 part of premix; The microecological regulator includes: 3 parts of Lactobacillus plantarum and 2 parts of fructooligosaccharide; The immune nutrition enhancer includes: 2.5 parts of tea polyphenols, 2.5 parts of ganoderma lucidum polysaccharide, 0.6 part of L - arginine, and 0.4 part of L - glutamine.

[0014] Feeding method: S1. Select 35 - day - old white - feather broilers (average weight 2.2 kg), and determine them to be in the mid - growth stage; S2. Record the feeding behavior: daily feed intake is 150 g / head, feeding frequency is 11 times / day, and single - feeding duration is 8 minutes; S3. Immunological indicators obtained through monitoring: Serum IgG 6.8 mg / ml, Shannon index of intestinal flora 2.2, IL-6 42 pg / ml Environmental parameters: Ammonia concentration 16 ppm, carbon dioxide 2,800 ppm, Escherichia coli in bedding 1 × 10³ CFU / g S4. Dynamic adjustment: ① Since the ammonia concentration > 15 ppm, add 1 part of Bacillus subtilis to the microecological regulator; ② According to IL-6 > 40 pg / ml, increase the tea polyphenols in the immune enhancer to 2.7 parts; ② Regarding the relatively high feeding frequency, reduce 0.3 part of wheat bran and increase 0.3 part of fructooligosaccharide.

[0015] After 7 days of feeding, the feed-to-meat ratio of the experimental group with the adjusted formula decreased by 0.17 compared with the control group using the original formula, the serum IgG increased by 18%, and the Escherichia coli in the bedding decreased to 3 × 10² CFU / g.

[0016] Example 2 This example is a feed that can improve the immunity of poultry, including 88 parts of basic feed components, 5 parts of microecological precise regulator, and 6 parts of immune nutrition enhancer; The basic feed components include: 62 parts of corn, 22 parts of soybean meal, 3 parts of wheat bran, 2 parts of fish meal, and 1 part of premix; The microecological regulator includes: 3 parts of Enterococcus faecalis and 2 parts of galactooligosaccharide; The immune nutrition enhancer includes: 2.5 parts of grape seed extract, 2.5 parts of lentinan, and 1 part of L-cysteine.

[0017] Feeding method: S1. Select 28-day-old Cherry Valley meat ducks (average weight 1.8 kg), and determine them to be in the rapid growth stage; S2. Record the feeding behavior: Daily feed intake 180 g / duck, feeding frequency 9 times / day, single feeding duration 10 minutes; S3. Immunological indicators obtained through monitoring: Serum IgG 5.8 mg / ml, Shannon index of intestinal flora 1.9, IL-6 48 pg / ml; Environmental parameters: Ammonia concentration 18 ppm, carbon dioxide 3,000 ppm, positive detection of Salmonella in bedding; S4. Dynamic adjustment: ① Since the ammonia concentration > 15 ppm, add 1 part of Bacillus subtilis to the microecological regulator; ② According to IL-6 > 45 pg / ml, increase the grape seed extract in the immune enhancer to 2.8 parts; ③ For Salmonella contamination, reduce fish meal by 0.5 parts and increase galactooligosaccharide by 0.5 parts.

[0018] After 7 days of feeding, in the experimental group with the adjusted formula compared to the control group: the feed-to-meat ratio decreased by 0.15, serum IgG increased by 22%, and Salmonella turned negative.

[0019] Example 3 This example is a feed that can improve the immunity of poultry, including 90 parts of basic feed components, 4 parts of microecological precise regulator, and 6 parts of immune nutrition enhancer; The basic feed components include: 65 parts of corn, 20 parts of soybean meal, 5 parts of wheat bran, 1.5 parts of fish meal, and 1.5 parts of premix; The microecological regulator includes: 2.5 parts of Lactobacillus acidophilus and 1.5 parts of fructooligosaccharide; The immune nutrition enhancer includes: 2.5 parts of rosemary extract, 2 parts of astragalus polysaccharide, and 1.5 parts of L-glutamine.

[0020] Feeding method: S1. Select 42-day-old Lionhead geese (average weight 3.5 kg) and determine it as the fattening period; S2. Record the feeding behavior: daily feed intake 220 g / head, feeding frequency 8 times / day, single feeding duration 12 minutes; S3. Monitor and obtain immune indexes: serum IgG 7.2 mg / ml, intestinal flora Shannon index 2.4, IL-6 35 pg / ml; Environmental parameters: ammonia concentration 12 ppm, carbon dioxide 2500 ppm, litter humidity 40%; S4. Dynamic adjustment: ① Because the litter humidity > 35%, reduce wheat bran in the basic feed by 1 part; ② According to the feed intake > 200 g / head, increase astragalus polysaccharide in the immune enhancer to 2.5 parts; ④ For high feed intake, increase fructooligosaccharide by 0.5 part.

[0021] After 7 days of feeding, in the experimental group with the adjusted formula compared to the control group: the feed-to-meat ratio decreased by 0.12, the diversity of intestinal flora increased by 18%, and the litter humidity decreased to 32%.

[0022] The technical features not described in the present invention can be achieved by or adopted the existing technology, and will not be elaborated here. Of course, the above description is not a limitation to the present invention, and the present invention is not limited to the above examples. The changes, modifications, additions or substitutions made by those of ordinary skill in the art within the essence scope of the present invention should also belong to the protection scope of the present invention.

Claims

1. A feed that can enhance the immunity of poultry, characterized in that, It includes a basic feed component, a precise microecological regulator, and an immune nutrition enhancer. Among them, the basic feed component is 85 - 90 parts, the precise microecological regulator is 4 - 6 parts, and the immune nutrition enhancer is 4 - 6 parts; The basic feed component includes 60 - 65 parts of corn, 20 - 25 parts of soybean meal, 2 - 5 parts of wheat bran, 1 - 3 parts of fish meal, and 1 - 2 parts of premix; The microecological regulator includes 2.5 - 3.5 parts of probiotics and 1.0 - 2.5 parts of prebiotics. The immune nutrition enhancer includes 1.5 - 2.5 parts of natural polyphenols, 1.5 - 2.5 parts of polysaccharides, and 1.0 - 1.5 parts of amino acids.

2. The feed and feeding method capable of improving the immunity of poultry bodies according to claim 1, characterized in that, The probiotics in the microecological regulator are selected from one or more of the genera Lactobacillus, Bifidobacterium, and Bacillus.

3. The feed and feeding method for improving the immunity of poultry body according to claim 1, characterized in that, The prebiotics in the microecological regulator are one or more of fructooligosaccharide and galactooligosaccharide.

4. The feed and feeding method capable of improving the immunity of poultry bodies according to claim 1, characterized in that The natural polyphenols in the immune nutrition enhancer are selected from one or more of tea polyphenols, grape seed extract, rosemary extract, or pomegranate polyphenols.

5. The feed and feeding method capable of enhancing the immunity of poultry bodies according to claim 1, wherein The polysaccharide components in the immune nutrition enhancer include one or more of ganoderma lucidum polysaccharide, lentinan, or astragalus polysaccharide.

6. The feed and feeding method capable of enhancing the immunity of poultry body according to claim 1, characterized in that The amino acids in the immune nutrition enhancer are one or more of arginine, glutamine, and cysteine.

7. The feeding method of the feed capable of enhancing the immunity of poultry body according to any one of claims 1-6, characterized in that, It includes the following steps: S1. Determine the growth stage of the poultry according to its breed, age, and weight; S2. Record the feeding behavior data of the poultry; S3. Monitor the changes in immune - related indicators of the poultry and environmental parameters in the poultry house; S4. Dynamically adjust the addition ratios of the basic feed, microecological regulator, and immune nutrition enhancer in the feed according to the records and monitoring results of S1 - S3, and implement the linkage regulation measures of feed and environment.

8. The feeding method of the feed capable of enhancing the immunity of poultry bodies according to claim 7, characterized in that, The immune - related indicators include serum immunoglobulin level, intestinal flora diversity, and inflammatory factor expression level, which are regularly sampled and analyzed through a data acquisition system; The adjustment of the dynamic formula is based on establishing an immune response evaluation model, and the ingredients are carried out through the feedback results of the model.

9. The feeding method of the feed capable of enhancing the immunity of poultry bodies according to claim 8, characterized in that, The environmental parameters in the poultry house include ammonia concentration, carbon dioxide concentration, suspended particulate matter concentration, microbial content in water, and bacterial population in litter.

10. The feeding method of the feed capable of enhancing the immunity of poultry body according to claim 9, characterized in that, The model comprehensively inputs the immune - related indicators of the poultry body, feeding behavior data, and environmental parameters in the poultry house, and dynamically predicts the immune status and conducts risk grading through machine learning algorithms. The feedback results are used to adjust the feed nutrition ratio and additive level.