Composition helpful for maintaining healthy level of blood sugar and health food containing same

Abstract

The invention discloses a composition helpful for maintaining the healthy level of blood sugar. The composition is prepared from the following components in parts by weight: 10-40 parts of diglyceride powder, 15-40 parts of soybean protein isolate, 10-30 parts of xylooligosaccharide, 1-4 parts of mulberry leaf extract, 1-4 parts of radix puerariae extract and 1-4 parts of radix astragali seu hedysari extract. According to the composition disclosed by the invention, a multi-dimensional regulation and control network of metabolic regulation, nutritional supplement and micro-ecological balance can be formed, so that a plurality of components generate a synergistic effect on blood sugar regulation, and the blood sugar regulation capability is remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of functional foods, and particularly relates to a composition helpful for maintaining a healthy blood glucose level and a health food containing the same. Background Art

[0002] Globally, blood glucose health management has become an important public health issue. According to the data of the International Diabetes Federation (IDF) in 2023, approximately 570 million adults worldwide are troubled by hyperglycemia and prediabetes. In China, the prevalence of diabetes in adults has reached 12.8%, and it shows a trend of getting younger. The existing blood glucose management methods mainly rely on drug intervention and dietary regulation. However, long-term drug use may be accompanied by side effects such as gastrointestinal reactions, and traditional functional foods have problems such as single composition, insufficient efficacy, or poor taste. Therefore, there is an urgent clinical and market demand to develop a safe and effective new blood glucose management composition.

[0003] Currently, commercially available blood glucose management health foods are mainly divided into two categories. One is the plant extract compound type: such as the blood glucose-lowering assisting health food disclosed in Chinese Patent with the publication number CN106666312A, which takes plant extracts such as kelp, kudzu root, mulberry leaf, and astragalus as core components, supplemented with prebiotics such as fructooligosaccharide. This type of product relies on active substances such as polyphenols and polysaccharides in natural plants to play a role, but has the following defects: (1) Insufficient component synergy: The active ingredients in plant extracts (such as DNJ in mulberry leaf and puerarin) are mostly lipophilic or macromolecular structures, and the intestinal absorption rate is low when directly compounded (the absorption rate of flavonoids is less than 20% under conventional processes); (2) Single efficacy: It only focuses on the regulation of blood glucose level and does not involve the core pathological mechanisms of blood glucose abnormalities such as insulin resistance and intestinal flora imbalance.

[0004] The other is the nutritional meal replacement type: such as the full-nutrition meal replacement powder disclosed in Chinese Patent with the publication number CN118402621A, which provides a sense of fullness through components such as skim milk powder, soy protein isolate, and olive diglyceride, reducing the absorption of sugars. The limitations of this type of product are: (1) Weak targeting for blood glucose regulation: It mainly indirectly improves blood glucose through calorie restriction, and has limited intervention effects on postprandial blood glucose fluctuations (such as too high blood glucose peaks); (2) Single function: It takes weight loss as the core goal and lacks a systematic design for maintaining blood glucose homeostasis.

[0005] Therefore, it is of great practical significance to develop a composition that is safe, effective and helpful for maintaining a healthy blood glucose level. Summary of the Invention

[0006] Therefore, based on the defects of the above-mentioned prior art, the present invention provides a composition helpful for maintaining a healthy blood glucose level and a health food containing the composition.

[0007] To solve the above technical problems, the present invention provides the following technical solutions:

[0008] In the first aspect of the present invention, a composition helpful for maintaining a healthy blood glucose level is provided, which comprises the following components by weight: 10 - 40 parts of diglyceride powder, 15 - 40 parts of soy protein isolate, 10 - 30 parts of xylo-oligosaccharide, 1 - 4 parts of mulberry leaf extract, 1 - 4 parts of kudzu root extract, and 1 - 4 parts of astragalus root extract.

[0009] Further, the composition further comprises 0.1 - 1 part of chromium yeast.

[0010] Further, the weight ratio of the diglyceride powder to the soy protein isolate is 1:1.2 - 1:2.

[0011] Further, the weight ratio of the mulberry leaf extract, kudzu root extract, and astragalus root extract is 2:1:1.

[0012] Further, in some preferred embodiments, the composition helpful for maintaining a healthy blood glucose level comprises the following components by weight: 10 - 25 parts of diglyceride powder, 20 - 40 parts of soy protein isolate, 15 - 30 parts of xylo-oligosaccharide, 2 - 4 parts of mulberry leaf extract, 1 - 3 parts of kudzu root extract, 1 - 3 parts of astragalus root extract, and 0.1 - 0.5 part of chromium yeast.

[0013] Further, in some preferred embodiments, the composition helpful for maintaining a healthy blood glucose level comprises the following components by weight: 20 parts of diglyceride powder, 30 parts of soy protein isolate, 25 parts of xylo-oligosaccharide, 4 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus root extract, and 0.3 part of chromium yeast.

[0014] In the second aspect of the present invention, a preparation method of the composition helpful for maintaining a healthy blood glucose level is provided, comprising the following steps:

[0015] S1. Prepare an aqueous solution of wall material by mixing gum arabic and maltodextrin, add mulberry leaf extract, kudzu root extract, astragalus root extract, and chromium yeast as core materials, and at the same time add an emulsifier, and mix under a high-speed disperser to form a uniform suspension; then perform high-pressure homogenization treatment 1 - 3 times to make the particle size of the suspension ≤ 5 μm;

[0016] S2. Spray-dry the suspension, and screen the obtained powder to collect microcapsules with a particle size of 20 - 100 μm;

[0017] S3. Mix the diglyceride powder, soy protein isolate, xylo-oligosaccharide, and the microcapsules prepared in step S2 evenly to obtain the composition helpful for maintaining a healthy blood glucose level.

[0018] Further, the preparation method further satisfies any one of the following:

[0019] (1) The mass ratio of the gum arabic to the maltodextrin is 1:2;

[0020] (2) The concentration of the aqueous solution is 10-20% (w / v);

[0021] (3) The emulsifier is Tween-80, and its addition amount is 0.5-1 wt% of the total mass of the wall material;

[0022] (4) The mass ratio of the core material to the wall material is 1:(2-3);

[0023] (5) The rotation speed of the high-speed mixer is 1000-2000 r / min, and the mixing time is 10-30 min;

[0024] (6) The pressure of the high-pressure homogenization is 40-60 MPa, and the temperature is 40-50 °C;

[0025] (7) The parameters of the spray drying are: the inlet air temperature is 160-180 °C, the outlet air temperature is 80-90 °C, the rotation speed of the atomizer is 20000-25000 r / min, and the feed flow rate is 30-50 mL / min.

[0026] The third aspect of the present invention provides a health food, and the health food contains the above-mentioned composition with the effects of anti-fatigue and uric acid reduction.

[0027] Further, the health food further includes excipients, and the excipients include at least one of a filler, a food flavor, an acidulant, a sweetener, and a diluent.

[0028] Further, the filler is one or more of fructose, erythritol, isomaltitol, mannitol, starch, and dextrin.

[0029] Further, the food flavor is one or more of orange flavor, lemon flavor, strawberry flavor, blueberry flavor, apple flavor, and rose flavor.

[0030] Further, the sweetener is one or more of brown sugar, trichloroglucose, stevioside, aspartame, and neotame.

[0031] Further, the acidulant is one or more of citric acid, lactic acid, tartaric acid, fumaric acid, and sodium citrate.

[0032] Further, the diluent is one or more of water, edible vegetable oil, and polyethylene glycol.

[0033] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0034] 1. For the composition provided by the present invention, diglyceride powder can regulate lipid metabolism, soy protein isolate can provide branched-chain amino acids, xylo-oligosaccharide has higher prebiotic activity, which is beneficial to the proliferation of intestinal probiotics, thus reshaping the intestinal flora, and chromium yeast can enhance insulin sensitivity. When they are used in combination with traditional Chinese medicine extracts (mulberry leaf extract, kudzu root extract, astragalus extract), a multi-dimensional regulation network of "metabolism regulation - nutritional supplementation - microecological balance" can be formed, so that various components have a synergistic effect on blood glucose regulation, significantly improving the ability of blood glucose regulation.

[0035] 2. Microencapsulation technology is a process of encapsulating core active ingredients (core materials) in polymer materials (wall materials) to form tiny capsules, which can protect the stability of the core materials and achieve targeted release. In the present invention, gum arabic and maltodextrin are used as wall materials to microencapsulate mulberry leaf extract, kudzu root extract, astragalus extract and chromium yeast, improving the stability of the active ingredients, protecting the active ingredients from gastrointestinal tract damage, achieving targeted release of the active ingredients in the colon, and having a sustained-release effect, greatly prolonging the action time of the composition and improving the efficacy of blood glucose regulation.

[0036] 3. The composition provided by the present invention can supplement high-quality nutrients such as proteins and fats required by the body in daily applications, and also helps to maintain a healthy blood glucose level. It can be applied to various health foods, enabling them to have the efficacy of regulating blood glucose and maintaining a healthy blood glucose level. Detailed Embodiments

[0037] The present invention will be further described below in conjunction with specific embodiments, so that those skilled in the art can better understand the present invention and be able to implement it, but the exemplified embodiments are not intended to limit the present invention.

[0038] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present invention belongs. The terms used in the description of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0039] Unless otherwise specified, the experimental methods used in the following examples and comparative examples are all conventional methods, and the materials, reagents, etc. used, unless otherwise specified, can be obtained from commercial channels.

[0040] Example 1

[0041] This embodiment provides a composition that helps maintain a healthy blood glucose level, comprising the following components by weight: 20 parts of diglyceride powder, 30 parts of soy protein isolate, 25 parts of xylooligosaccharide, 4 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus root extract, and 0.3 parts of chromium yeast.

[0042] The preparation method of the composition of this embodiment includes the following steps:

[0043] S1. Mix gum arabic and maltodextrin in a ratio of 1:2 to prepare an aqueous solution with a concentration of 15% (w / v).

[0044] S2. According to the ratio of core material: wall material = 1:2, add 4 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus root extract, and 0.3 parts of chromium yeast to the above aqueous solution, and add 0.5 wt% of Tween-80 based on the weight of the wall material. Mix at a speed of 2000 r / min for 30 min under a high-speed disperser to form a uniform suspension.

[0045] S3. Subject the above suspension to high-pressure homogenization treatment twice. The pressure of high-pressure homogenization is 60 MPa and the temperature is 50 °C to make the particle size of the suspension ≤ 5 μm.

[0046] S4. Spray-dry the above suspension: set the inlet air temperature to 180 °C, the outlet air temperature to 90 °C, the atomizer rotation speed to 20000 r / min, and the feed flow rate to 50 mL / min. The powder obtained after drying is sieved through an 80-mesh sieve, and microcapsules with a particle size of 20 - 100 μm are collected.

[0047] S5. Mix 20 parts of diglyceride powder, 30 parts of soy protein isolate, 25 parts of xylooligosaccharide with the microcapsules prepared above evenly to obtain the composition that helps maintain a healthy blood glucose level.

[0048] Example 2

[0049] This embodiment provides a composition that helps maintain a healthy blood glucose level, comprising the following components by weight: 15 parts of diglyceride powder, 30 parts of soy protein isolate, 20 parts of xylooligosaccharide, 3 parts of mulberry leaf extract, 3 parts of kudzu root extract, 3 parts of astragalus root extract, and 0.5 parts of chromium yeast.

[0050] The preparation method of the composition of this embodiment includes the following steps:

[0051] S1. Mix gum arabic and maltodextrin in a ratio of 1:2 to prepare an aqueous solution with a concentration of 12% (w / v).

[0052] S2. According to the ratio of core material: wall material = 1:3, add 3 parts of mulberry leaf extract, 3 parts of kudzu root extract, 3 parts of astragalus root extract and 0.5 part of chromium yeast to the above aqueous solution, and add Tween-80 accounting for 1 wt% of the weight of the wall material. Mix at a speed of 2000 r / min for 30 min under a high-speed disperser to form a uniform suspension.

[0053] S3. Subject the above suspension to high-pressure homogenization treatment twice. The pressure of high-pressure homogenization is 60 MPa and the temperature is 50 °C to make the particle size of the suspension ≤ 5 μm.

[0054] S4. Spray-dry the above suspension: set the inlet air temperature to 180 °C, the outlet air temperature to 90 °C, the atomizer speed to 20000 r / min, and the feed flow rate to 50 mL / min. The powder obtained after drying is screened through an 80-mesh sieve, and microcapsules with a particle size of 20 - 100 μm are collected.

[0055] S5. Mix 15 parts of diglyceride powder, 30 parts of soy protein isolate, 20 parts of xylo-oligosaccharide with the above-prepared microcapsules evenly to obtain the composition helpful for maintaining a healthy blood sugar level.

[0056] Example 3

[0057] This example provides a composition helpful for maintaining a healthy blood sugar level, including the following components by weight: 25 parts of diglyceride powder, 40 parts of soy protein isolate, 15 parts of xylo-oligosaccharide, 2 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus root extract, and 0.8 part of chromium yeast.

[0058] The preparation method of the composition in this example includes the following steps:

[0059] S1. Mix gum arabic and maltodextrin according to the ratio of 1:2 to prepare an aqueous solution with a concentration of 10% (w / v);

[0060] S2. According to the ratio of core material: wall material = 1:2, add 2 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus root extract and 0.8 part of chromium yeast to the above aqueous solution, and add Tween-80 accounting for 0.8 wt% of the weight of the wall material. Mix at a speed of 2000 r / min for 30 min under a high-speed disperser to form a uniform suspension.

[0061] S3. Subject the above suspension to high-pressure homogenization treatment twice. The pressure of high-pressure homogenization is 60 MPa and the temperature is 50 °C to make the particle size of the suspension ≤ 5 μm.

[0062] S4. Spray-dry the above suspension: Set the inlet air temperature to 180 °C, the outlet air temperature to 90 °C, the atomizer rotation speed to 20,000 r / min, and the feed flow rate to 50 mL / min. The powder obtained after drying is screened through an 80-mesh sieve, and microcapsules with a particle size of 20 - 100 μm are collected.

[0063] S5. Mix 25 parts of diglyceride powder, 40 parts of soy protein isolate, 15 parts of xylo-oligosaccharide with the microcapsules prepared above evenly to obtain the composition helpful for maintaining a healthy blood glucose level.

[0064] Example 4

[0065] This example provides a composition helpful for maintaining a healthy blood glucose level, which is different from Example 1 in that: the composition does not contain 0.3 parts of chromium yeast.

[0066] Comparative Example 1

[0067] This comparative example provides a composition helpful for maintaining a healthy blood glucose level, which is different from Example 1 in that: diglyceride powder is not added, and correspondingly, 20 parts more of soy protein isolate are added.

[0068] Comparative Example 2

[0069] This comparative example provides a composition helpful for maintaining a healthy blood glucose level, which is different from Example 1 in that: mulberry leaf extract is not added, and correspondingly, 2 parts more of kudzu root extract and 2 parts more of astragalus root extract are added.

[0070] Comparative Example 3

[0071] This comparative example provides a composition helpful for maintaining a healthy blood glucose level, which is different from Example 1 in that: xylo-oligosaccharide is replaced with fructo-oligosaccharide.

[0072] Comparative Example 4

[0073] This comparative example provides a composition helpful for maintaining a healthy blood glucose level, which is different from Example 1 in that: mulberry leaf extract, kudzu root extract, astragalus root extract and chromium yeast are not microencapsulated, but directly mixed with diglyceride powder, soy protein isolate and xylo-oligosaccharide.

[0074] Experiment 1: Hypoglycemic experiment on normal mice

[0075] This experiment was carried out according to the animal experiment (Protocol 1) of the "Technical Guidelines for the Function Testing and Evaluation of Health Foods (2023 Edition)" for the test method of helping to maintain a healthy blood glucose level, specifically as follows:

[0076] Experimental animals: Healthy adult male C57BL / 6 mice were selected, and their body weights were controlled at 24 - 26 g. The mice were housed in an environment with a temperature of (22 ± 2)°C and a humidity of (50 ± 10)%, and were allowed free access to food and water. The experiment began after 7 days of environmental adaptation.

[0077] Grouping: A total of 50 mice were divided into 5 groups according to their blood glucose levels after fasting for 3 - 5 hours: a normal group and experimental groups (Examples 1 - 4), with 10 mice in each group.

[0078] Normal group: Distilled water was administered at a dose of 10 g / kg for 30 consecutive days.

[0079] Experimental groups: The compositions of Examples 1 - 4 were administered at a dose of 10 g / kg for 30 consecutive days.

[0080] The fasting blood glucose values of the mice in each group (after fasting for 5 hours) were measured, and the blood glucose values of the animals in each group were compared.

[0081] Data statistics: Statistical analysis was performed using SPSS 10.0 software. The data were expressed as , and the t - test was used for comparison between groups. One - way ANOVA was used for comparison of means among multiple groups. When P ≤ 0.05, it indicated a significant difference.

[0082] Table 1 Fasting blood glucose values of mice

[0083] Fasting blood glucose value (mmol / L) Normal group 4.3±0.4 Example 1 4.2±0.5 Example 2 4.3±0.2 Example 3 4.4±0.4 Example 4 4.2±0.1

[0084] Please refer to Table 1. The fasting blood glucose level of the mice in the normal group was (4.3 ± 0.4) mmol / L. After continuous feeding with the compositions of Examples 1 - 4 for 30 days, the fasting blood glucose levels of the mice remained between (4.2 - 4.4) mmol / L, and there was no significant statistical difference compared with the mice in the normal group, indicating that the compositions of Examples 1 - 4 had no effect on the blood glucose of normal mice.

[0085] Experiment 2: Hypoglycemic experiment on hyperglycemic model mice

[0086] This experiment was conducted according to the test method (Protocol 1) for helping to maintain a healthy blood glucose level in the "Technical Guidelines for the Function Testing and Evaluation of Health Foods (2023 Edition)" for animal experiments, as follows:

[0087] Experimental animals: Healthy adult male C57BL / 6 mice were selected, and their body weights were controlled at 24 - 26 g. The mice were housed in an environment with a temperature of (22 ± 2)°C and a humidity of (50 ± 10)%, and were allowed free access to food and water. The experiment began after 7 days of environmental adaptation.

[0088] Modeling method: Refer to the "Technical Guidelines for the Function Testing and Evaluation of Health Foods (2023 Edition)".

[0089] Grouping: A total of 90 hyperglycemic model mice were randomly divided into 9 groups: a model control group and experimental groups (Examples 1-4, Comparative Examples 1-4), with 10 mice in each group.

[0090] Normal group: Distilled water was administered at a dose of 4 g / kg for 30 consecutive days.

[0091] Experimental groups: The compositions of Examples 1-4 and Comparative Examples 1-4 were administered at a dose of 4 g / kg for 30 consecutive days.

[0092] After continuous feeding for 30 days, the fasting blood glucose values of the mice in each group were measured and the blood glucose decline rate was calculated.

[0093] Data statistics: Statistical processing was performed using SPSS 10.0 software. The data were expressed as , and the t-test was used for comparison between groups. One-way ANOVA was used for comparison of means among multiple groups. When P≤0.05, it indicated a significant difference.

[0094] Table 2 Results of blood glucose decline rate in mice

[0095] Blood glucose decline rate (%) Model control group 1.6±1.5 Example 1 <![CDATA[59.5±10.5 ** > Example 2 <![CDATA[57.3±8.7 ** > Example 3 <![CDATA[59.8±11.2 ** > Example 4 <![CDATA[50.3±12.2 ** > Comparative example 1 <![CDATA[44.1±10.4 ** > Comparative example 2 <![CDATA[49.5±9.8 ** > Comparative example 3 <![CDATA[54.3±10.9 ** > Comparative example 4 <![CDATA[39.7±8.2 ** >

[0096] Note: *, ** indicate comparison with the normal control group, * p < 0.05, ** p < 0.01.

[0097] Please refer to Table 2. Compared with the model control group, after continuous feeding of the compositions of Examples 1-4 for 30 days, the blood glucose decline rate of the mice increased significantly, indicating that the compositions of the present invention can reduce the fasting blood glucose value of hyperglycemic mice and are beneficial to maintaining blood glucose stability. Among them, compared with Example 4, 0.3 parts of chromium yeast were added to the composition of Example 1. Since chromium can enhance insulin sensitivity and the addition of chromium yeast is beneficial to regulating the intestinal flora, it can better maintain blood glucose stability. Therefore, the fasting blood glucose value of the mice in Example 1 decreased more significantly compared with Example 4.

[0098] In Comparative Examples 1-2, when the composition did not contain diglyceride powder and mulberry leaf extract, the fasting blood glucose decline rate of the mice decreased significantly compared with Example 1. This shows that components such as diglyceride powder, soy protein isolate, xylo-oligosaccharide, mulberry leaf extract, pueraria root extract, and astragalus root extract in the composition of the present invention have a synergistic effect on blood glucose regulation. The lack of any one of these components will lead to a significant reduction in the blood glucose-lowering effect.

[0099] In Comparative Example 3, xylooligosaccharide in the composition was replaced with fructooligosaccharide, and the fasting blood glucose reduction rate of the mice also decreased significantly compared with that in Example 1. This is because xylooligosaccharide has higher prebiotic activity, and its ability to proliferate Bifidobacterium is dozens of times that of fructooligosaccharide. It is more conducive to the proliferation of intestinal probiotics, can reshape the intestinal flora, and thus can promote the blood glucose-lowering effect and maintain the blood glucose stability of the mice.

[0100] In Comparative Example 4, the mulberry leaf extract, kudzu root extract, astragalus extract and chromium yeast were not microencapsulated, but directly mixed with diglyceride powder, soy protein isolate and xylooligosaccharide. From the results, the fasting blood glucose reduction rate of the mice decreased significantly compared with that in Example 1. This is because after the active components in Example 1 were microencapsulated, their stability was greatly improved. The microencapsulation protected the active ingredients from gastrointestinal damage, enabled the targeted release of the active ingredients at the colon site, and had a sustained-release effect, thus greatly prolonging the action time of the composition and improving the blood glucose regulation efficacy. Therefore, the fasting blood glucose reduction rate of the mice in Example 1 was significantly higher than that in Comparative Example 4.

[0101] The above-mentioned embodiments are only preferred embodiments given to fully illustrate the present invention, and the protection scope of the present invention is not limited thereto. Equivalent substitutions or transformations made by those skilled in the art on the basis of the present invention are all within the protection scope of the present invention. The protection scope of the present invention shall be subject to the claims.

Claims

1. A composition that helps maintain a healthy blood glucose level, characterized in that, It comprises the following components by weight parts: 10-40 parts of diglyceride powder, 15-40 parts of soy protein isolate, 10-30 parts of xylo-oligosaccharide, 1-4 parts of mulberry leaf extract, 1-4 parts of kudzu root extract, and 1-4 parts of astragalus extract.

2. A composition for helping maintain a healthy blood glucose level according to claim 1, characterized in that, The composition further comprises 0.1-1 part of chromium yeast.

3. A composition for helping to maintain a healthy blood glucose level according to claim 1, characterized in that, The weight ratio of the diglyceride powder to the soy protein isolate is 1:1.2-1:

2.

4. A composition for helping to maintain a healthy blood glucose level according to claim 1, characterized in that, The weight ratio of the mulberry leaf extract, kudzu root extract, and astragalus extract is 2:1:

1.

5. A composition according to claim 2, which is helpful for maintaining a healthy blood glucose level, characterized in that, It comprises the following components by weight parts: 10-25 parts of diglyceride powder, 20-40 parts of soy protein isolate, 15-30 parts of xylo-oligosaccharide, 2-4 parts of mulberry leaf extract, 1-3 parts of kudzu root extract, 1-3 parts of astragalus extract, and 0.1-0.5 part of chromium yeast.

6. A composition according to claim 5 for assisting in maintaining a healthy blood glucose level, characterized in that, It comprises the following components by weight parts: 20 parts of diglyceride powder, 30 parts of soy protein isolate, 25 parts of xylo-oligosaccharide, 4 parts of mulberry leaf extract, 2 parts of kudzu root extract, 2 parts of astragalus extract, and 0.3 part of chromium yeast.

7. The method for preparing a composition according to claim 2, which is helpful for maintaining a healthy blood glucose level, is characterized in that, It includes the following steps: S1. Prepare an aqueous solution of wall material by mixing gum arabic and maltodextrin, add mulberry leaf extract, kudzu root extract, astragalus extract, and chromium yeast as core materials, and at the same time add an emulsifier, and mix under a high-speed disperser to form a uniform suspension; then perform high-pressure homogenization treatment 1-3 times to make the particle size of the suspension ≤ 5 μm; S2. Spray-dry the suspension, sieve the obtained powder, and collect microcapsules with a particle size of 20-100 μm; S3. Mix the diglyceride powder, soy protein isolate, xylo-oligosaccharide, and the microcapsules prepared in step S2 evenly to obtain the composition helpful for maintaining a healthy blood sugar level.

8. The preparation method of a composition for helping to maintain a healthy blood glucose level according to claim 7, characterized in that, The preparation method further satisfies any one of the following: (1) The mass ratio of the gum arabic to the maltodextrin is 1:2; (2) The concentration of the aqueous solution is 10-20% (w / v); (3) The emulsifier is Tween-80, and its addition amount is 0.5-1 wt% of the total mass of the wall material; (4) The mass ratio of the core material to the wall material is 1:(2-3); (5) The rotation speed of the high-speed mixer is 1000-2000 r / min, and the mixing time is 10-30 min; (6) The pressure of the high-pressure homogenization is 40-60 MPa, and the temperature is 40-50 °C; (7) The parameters of the spray drying are: inlet air temperature is 160-180 °C, outlet air temperature is 80-90 °C, atomizer rotation speed is 20000-25000 r / min, and feed flow rate is 30-50 mL / min.

9. A health food, characterized in that, The health food contains the composition with anti-fatigue and uric acid-lowering effects according to any one of claims 1-6.

10. The health food according to claim 9, wherein, It further comprises excipients, and the excipients comprise at least one of a filler, an acidulant, a diluent, and a thickener.