Multifunctional alcohol-free hair care composition

Abstract

The present invention relates to a transparent hair care composition comprising a substituted 2-hydroxypyridine-N-oxide material; a diol; a nonionic surfactant; a carboxylic acid or a polyacid; water or an aqueous carrier; wherein the composition has a pH of from about 3.5 to about 6.0; and wherein the composition is free of alcohol.

Description

Technical Field

[0001] The present invention relates to multifunctional alcohol-free hair care compositions. Background Art

[0002] For many years, anti-dandruff rinse-off preparations (shampoos, scalp treatments) have been widely used to treat dandruff and clean the hair and scalp. However, for consumers with severe dandruff problems (such as flaking, itching, or an oily or dry scalp), using only anti-dandruff shampoo is generally not enough. This is because the deposition or delivery of anti-dandruff active substances to the scalp is limited by the use of only a single product. Although anti-dandruff conditioners have been available on the market for many years, these rinse-off anti-dandruff conditioners are highly viscous and greasy-looking products. In fact, these products are usually just ordinary hair conditioning products with added anti-dandruff active substances. As a result, most consumers apply these products carefully to their hair while deliberately avoiding contact of these products with their scalp, which means that consumers do not obtain the anti-dandruff benefits of these products. Leave-in anti-dandruff products come in various forms, such as spray tonics, lotions, and creams, but the problem with these products is that, while they can provide anti-dandruff benefits, they all use ethanol to dissolve the oil-soluble anti-dandruff active, resulting in opacity and a sticky feeling after application. Due to the strong odor of ethanol and the opacity of the product, the greasiness upon application, which means it is full of chemicals, it is not advisable to use it every day, and these products are not very popular in the market. Most consumers are looking for clear, ethanol-free, natural-looking products that can provide scalp benefits (such as anti-dandruff, anti-itching, etc.) and are not sticky after application. Therefore, there is a need for a multifunctional hair care composition that consumers can apply to their scalp to provide scalp benefits, such as anti-dandruff, anti-itching effects, while being clear, ethanol-free, and not sticky after application, which is what consumers expect and want.

[0003] Furthermore, consumers prefer to minimize the number of ingredients in their products and want to understand why each ingredient is needed. Many consumers seek labels stating that a composition is free of unnecessary chemicals, particularly for products applied directly to the scalp, which may already be sensitive due to the flaking and itching symptoms of dandruff. Therefore, the present invention has eliminated or minimized the number of ingredients that do not contribute significantly to the consumer's benefit, such as preservatives, stabilizers, or solvents.

[0004] Therefore, there is a continuing need for leave-on formulations that not only provide scalp benefits, such as anti-dandruff, anti-itch benefits, but are also alcohol-free, clear, non-sticky upon application, while being formulated with natural and multifunctional materials. Summary of the Invention

[0005] The present invention relates to a transparent hair care composition comprising a substituted 2-hydroxypyridine-N-oxide material; a glycol; a nonionic surfactant; a monocarboxylic acid or a polyacid; water or an aqueous carrier; wherein the composition has a pH of from about 3.5 to about 6.0; and wherein the composition is free of alcohol. DETAILED DESCRIPTION

[0006] While the specification concludes with claims which particularly point out and distinctly claim the invention, it is believed the present invention will be better understood from the following description.

[0007] As used herein, "comprising" means that other steps and other ingredients that do not affect the end result can be added. This term encompasses the terms "consisting of" and "consisting essentially of." As used herein, "consisting essentially of" means that a composition or component may include additional ingredients so long as the additional ingredients do not materially alter the basic and novel characteristics of the claimed composition or method.

[0008] Unless otherwise indicated, all percentages, parts and ratios are based on the total weight of the compositions of the present invention. All such weights pertaining to listed ingredients are based on the active content and, therefore, do not include carriers or by-products that may be contained in commercially available materials. Unless otherwise indicated, all measurements are understood to be made under ambient conditions, wherein "ambient conditions" refers to conditions at about 25°C, at about one atmosphere of pressure, and at about 50% relative humidity (RH). All numerical ranges are inclusive of narrower ranges; the upper and lower limits of the ranges described are combinable to form additional ranges not expressly stated.

[0009] As used herein, "mixture" is intended to include both simple combinations of substances as well as any compounds that can result from their combination.

[0010] As used herein, unless otherwise indicated, the term "molecular weight" or "M.Wt." refers to weight average molecular weight. "QS" means qs to 100%.

[0011] "Applying" or "applying" as used with reference to a composition means applying or spreading the composition of the present invention onto keratinous tissue such as hair.

[0012] "Dermatologically acceptable" means that the compositions or components described are suitable for use in contact with human skin tissue without undue toxicity, incompatibility, instability, allergic response, and the like.

[0013] A "safe and effective amount" refers to an amount of a compound or composition sufficient to significantly induce a positive beneficial effect.

[0014] "Rinse-off" with respect to a composition refers to a composition that is intended to be applied to a keratinous substrate and subsequently removed from the application within a few minutes or less by washing, rinsing, or wiping. These "rinse-off" compositions are distinguished from "leave-on" compositions, which are intended to be applied to keratinous tissue and allowed to remain thereon for a longer period of time.

[0015] "Leave-in" with respect to a composition refers to a composition that is intended to be applied to and allowed to remain on keratinous tissue. These leave-in compositions are distinguished from compositions that are applied to the hair and subsequently removed (within a few minutes or less) by washing, rinsing, wiping, etc. Leave-in compositions do not include rinse-off applications such as shampoos, rinse-off conditioners, facial cleansers, hand soaps, body washes, or body washes. Leave-in compositions may be substantially free of cleansing or detersive surfactants. For example, a "leave-in composition" may be left on keratinous tissue for at least 5 minutes. For example, a leave-in composition may contain less than 1% detersive surfactant, less than 0.5% detersive surfactant, or 0% detersive surfactant. However, the composition may contain emulsifying, dispersing or other processing surfactants that are not intended to provide any significant cleansing benefit when applied topically to the hair.

[0016] "Soluble" means that at least about 0.1 g of solute dissolves in 100 ml of solvent at 25°C and 1 atm pressure.

[0017] As used herein, "hair" refers to mammalian hair, including scalp hair, facial hair, and body hair, particularly hair on the human head and scalp.

[0018] As used herein, "cosmetically acceptable" means that the composition, formulation or component in question is suitable for use in contact with human keratinous tissue without undue toxicity, incompatibility, instability, allergic response, etc. All compositions described herein intended for direct application to keratinous tissue are limited to those that are cosmetically acceptable.

[0019] As used herein, "derivatives" include, but are not limited to, amide, ether, ester, amino, carboxyl, acetyl, acid, salt, and / or alcohol derivatives of a given compound.

[0020] As used herein, "polymer" refers to a chemical substance formed by the polymerization of two or more monomers. As used herein, the term "polymer" shall include all materials made by the polymerization of monomers, as well as natural polymers. Polymers made from only one type of monomer are called homopolymers. Polymers made from two or more different types of monomers are called copolymers. The distribution of different monomers can be calculated statistically or in blocks, and both possibilities are applicable to the present invention. Unless otherwise specified, the term "polymer" as used herein includes any type of polymer, including homopolymers and copolymers.

[0021] Hair care composition

[0022] The hair care compositions of the present invention provide a combination of multifunctional ingredients that achieve multiple benefits, including anti-dandruff, anti-itch, soothing, fragrance, antiseptic, non-sticky feel, and dry conditioning, all with nine or fewer ingredients. The product is presented as a clear spray, but can also be formulated in a form somewhere between a cream and a lotion, and can be slightly translucent in appearance. While the present invention addresses the problem of providing a hair care composition that achieves the numerous described benefits without a large number of ingredients, it was further recognized that a single ingredient could provide multiple functions. The present invention involves formulating compositions with natural ingredients preferred by consumers. For example, the nonionic surfactant polyethoxylated sorbitan is naturally derived from plant oils and fats, allowing formulators the freedom to choose it as an emulsifier in an alcohol-free base.

[0023] Anti-dandruff active ingredients

[0024] Piroctone and salts of piroctone, such as piroctone olamine, are known to provide anti-dandruff benefits. However, piroctone olamine is typically supplied as a crystalline powder and is also known to have very limited solubility in water, which means that the challenge is to ensure dissolution of the anti-dandruff active in as simple a combination of materials as possible.

[0025] The present invention has found that certain solid organic compounds, such as piroctone and / or its salts, tend to crystallize under the following conditions:

[0026] - when the amount of solid organic compounds in the composition is increased, in particular 0.2% or more; and / or

[0027] - When the composition has a pH of about 3.5 to about 6.

[0028] Piroctone olamine salt in leave-on formulations is typically dissolved by high concentrations (>30%) of alcohol (e.g., ethanol) or emollients such as triethylhexanoate and octyldodecyl myristate. Oils are typically emulsified by suspension polymers (e.g., acrylates), resulting in opaque products with high viscosity, which can cause a sticky sensation after application. In contrast, the present invention does not use emollients, ethanol, and viscous polymers, but rather a mixture of glycols and nonionic surfactants in a specific ratio with the piroctone olamine salt to achieve the desired pH range, allowing the piroctone olamine salt to function and better deposit on the scalp. In this way, anti-dandruff efficacy and a non-sticky hair feel are achieved without using too much glycol.

[0029] In the present invention, the anti-dandruff active substance can be a substituted 2-hydroxypyridine-N-oxide material, such as piroctone olamine salt or ciclopirox olamine salt. Piroctone olamine salt and ciclopirox olamine salt are salts of piroctone and ciclopirox, respectively, with monoethanolamine. In a composition with an acidic pH, they become protonated to become piroctone and ciclopirox, respectively. In the present invention, the composition may have an acidic pH, may have a pH of about 2 to about 6, may have a pH of about 3.5 to about 6, or may have a pH of about 3.5 to about 5.

[0030] The present invention also includes one or more soluble scalp health active substances, which can be a material or mixture selected from the following: azoles, such as climbazole, ketoconazole, itraconazole, econazole and conazole; hydroxypyridones, such as piroctone olamine, ciclopirox, lilopirox and MEA-hydroxyoctoxypyridone; strobilurins, such as azoxystrobin; and metal chelators, such as 1,10-phenanthroline.

[0031] The azole-soluble scalp health active can be an imidazole selected from the group consisting of benzimidazole, benzothiazole, bifonazole, butoconazole nitrate, climbazole, clotrimazole, cruconazole, eberconazole, econazole, exinoconazole, fenticonazole, fluconazole, flutriazole, isoconazole, ketoconazole, lannoconazole, metronidazole, miconazole, neticonazole, omoconazole, oxiconazole nitrate, sertaconazole, sulconazole nitrate, tioconazole, thiazole, and mixtures thereof, or the azole antimicrobial agent is a triazole selected from the group consisting of terconazole, itraconazole, and mixtures thereof. The azole-soluble scalp health active can be ketoconazole. The sole soluble scalp health active can be ketoconazole.

[0032] These anti-dandruff and scalp health active compounds are insoluble in typical solvents (such as water) or aqueous mixtures, such as water containing even high levels of glycerin. They typically require high levels (greater than 5% or even greater than 10%) of emollient oils (such as triethylhexanoin, octyldodecanol myristate), or high levels (greater than 50%) of alcohols, such as ethanol. The former (oils) are known to cause an unpleasant oily feel to the scalp and hair, and the latter (alcohols) are known to be unsuitable for most consumers who are hesitant to apply them to scalps already sensitive due to dandruff symptoms. The present invention solubilizes these anti-dandruff actives through a combination of surfactants (primarily required for hair conditioning) and specific acids (primarily required for pH adjustment). Beyond these two substances, there is no need to formulate these anti-dandruff and scalp health actives into a soluble form in a liquid.

[0033] Any anti-dandruff active or other scalp active is present in the composition at a level of from about 0.01% to about 3% by weight of the composition. In the present invention, the anti-dandruff active or other scalp active may be present at about 0.1% to 2%; or at about 0.5% to 1% of the anti-dandruff active or other scalp active.

[0034] nonionic surfactants

[0035] The hair care compositions of the present invention may contain a nonionic surfactant. Nonionic surfactants are generally compounds produced by the condensation of alkylene oxide groups (hydrophilic) with an organic hydrophobic compound, which may be aliphatic or alkyl aromatic in nature, but may include other surfactants with uncharged groups. In the present invention, the nonionic surfactant may have an HLB value of 10 to 15. Examples of types of nonionic surfactants are:

[0036] a. Alkylphenol ethoxylates. Polyethylene oxide condensates of alkylphenols, such as condensation products of alkylphenols in a linear or branched configuration (containing from about 6 to 12 carbon atoms in the alkyl group) with ethylene oxide in an amount equal to 10 to 60 moles of ethylene oxide per mole of alkylphenol. For example, the alkyl substituents in such compounds may be derived from polymerized propylene, diisobutylene, octane, or nonane.

[0037] b. Polyethylene glycol / polypropylene glycol block copolymers. Those formed by the condensation of ethylene oxide with the product of the reaction of propylene oxide and ethylenediamine. The composition can vary depending on the desired balance between hydrophobic and hydrophilic elements. For example, compounds containing from about 40% to about 80% by weight ethylene oxide and having a molecular weight of from about 5,000 to about 11,000 are satisfactory. These compounds are formed by reacting ethylene oxide groups with a hydrophobic base composed of the reaction product of ethylenediamine and excess propylene oxide, the base having a molecular weight of from about 2,500 to 3,000.

[0038] c. Fatty alcohols and fatty acid ethoxylates. Condensation products of fatty alcohols in a linear or branched configuration (having 8 to 18 carbon atoms) with ethylene oxide, for example coconut alcohol ethylene oxide condensates having 10 to 30 moles of ethylene oxide per mole of coconut alcohol, the coconut alcohol moiety having 10 to 14 carbon atoms. Other ethylene oxide condensation products are ethoxylated fatty acid esters of polyols (e.g., Tween 20-polyoxyethylene (20) sorbitan monolaurate).

[0039] d. Long-chain tertiary amine oxides. Long-chain tertiary amine oxides that conform to the following general formula:

[0040] R1 R2 R3 N→O

[0041] Wherein R1 contains an alkyl, alkenyl or monohydroxyalkyl group of about 8 to about 18 carbon atoms, 0 to about 10 ethylene oxide moieties and 0 to 1 glyceryl moieties, and R2 and R3 contain 1 to about 3 carbon atoms and 0 to about 1 hydroxyl group, such as methyl, ethyl, propyl, hydroxyethyl or hydroxypropyl groups. The arrow in the formula is a conventional representation of a semi-polar bond. Examples of amine oxides suitable for use in the present invention include dimethyl-dodecylamine oxide, oleyl di(2-hydroxyethyl)amine oxide, dimethyloctylamine oxide, dimethyldecylamine oxide, dimethyltetradecylamine oxide, 3,6,9-trioxoheptadecyldiethylamine oxide, di(2-hydroxyethyl)-tetradecylamine oxide, 2-dodecyloxyethyldimethylamine oxide, 3-dodecyloxy-2-hydroxypropyldi(3-hydroxypropyl)amine oxide, dimethylhexadecylamine oxide.

[0042] e. Long-chain tertiary phosphine oxides. Long-chain tertiary phosphine oxides that conform to the following general formula:

[0043] RR'R″P→O

[0044] wherein R contains an alkyl, alkenyl, or monohydroxyalkyl group having a chain length ranging from 8 to 18 carbon atoms, 0 to about 10 ethylene oxide moieties, and 0 to about 1 glyceryl moiety, and R' and R" are each an alkyl or monohydroxyalkyl group containing 1 to 3 carbon atoms. The arrows in the formula are conventional representations of semi-polar bonds. Examples of suitable phosphine oxides are: dodecyldimethylphosphine oxide, tetradecylmethylethylphosphine oxide, 3,6,9-trioxaoctadecyldimethylphosphine oxide, hexadecyldimethylphosphine oxide, 3-dodecyloxy-2-hydroxypropylbis(2-hydroxyethyl)phosphine oxide, stearyldimethylphosphine oxide, cetylethylpropylphosphine oxide, oleyldiethylphosphine oxide, dodecyldiethylphosphine oxide, tetradecyldiethylphosphine oxide, dodecyldipropylphosphine oxide, dodecylbis(hydroxymethyl)phosphine oxide, dodecylbis(2-hydroxyethyl)phosphine oxide, tetradecylmethyl-2-hydroxypropylphosphine oxide, oleyldimethylphosphine oxide, 2-hydroxydodecyldimethylphosphine oxide.

[0045] f. Long chain dialkyl sulfoxides. Long chain dialkyl sulfoxides comprise a short chain alkyl or hydroxyalkyl group (typically methyl) having 1 to about 3 carbon atoms and a long hydrophobic chain containing an alkyl, alkenyl, hydroxyalkyl, or ketoalkyl group having about 8 to about 20 carbon atoms, 0 to about 10 ethylene oxide moieties, and 0 to 1 glyceryl moieties. Examples include: octadecyl methyl sulfoxide, 2-ketotridecyl methyl sulfoxide, 3,6,9-trioxaoctadecyl 2-hydroxyethyl sulfoxide, dodecyl methyl sulfoxide, oleyl 3-hydroxypropyl sulfoxide, tetradecyl methyl sulfoxide, 3-methoxytridecyl methyl sulfoxide, 3-hydroxytridecyl methyl sulfoxide, and 3-hydroxy-4-dodecoxybutyl methyl sulfoxide.

[0046] g. Alkyl polysaccharide (APS) surfactants, such as alkyl polyglycosides. This type of surfactant is an APS surfactant having a hydrophobic group of about 6 to about 30 carbon atoms and a polysaccharide (e.g., a polyglycoside) as the hydrophilic group. Optionally, a polyalkylene oxide group can connect the hydrophobic and hydrophilic portions. The alkyl group (i.e., the hydrophobic portion) can be saturated or unsaturated, branched or unbranched, and unsubstituted or substituted (e.g., having hydroxyl groups or cyclic rings).

[0047] h. Polyethylene glycol (PEG) glyceryl fatty acid esters, such as those of the formula R(O)OCH2CH(OH)CH2(OCH2CH2)nOH, wherein n is from about 5 to about 200, may be from about 20 to about 100, and R is an aliphatic hydrocarbon group having from about 8 to about 20 carbon atoms.

[0048] The compositions of the present invention may comprise Tween 80-polyoxyethylene (20) sorbitan monolaurate and may comprise from about 1% to about 15% of a nonionic surfactant, may comprise from 3% to 10% of a nonionic surfactant, and may comprise from 5% to 10% of a nonionic surfactant.

[0049] Monocarboxylic acids and polyacids

[0050] The monocarboxylic acid can be an alpha-hydroxy acid (AHA), a beta-hydroxy acid (BHA) or a polyhydroxy acid (PHA). The BHA can be salicylic acid, which reduces or eliminates the need for adding preservatives. In the present invention, the acid can be lactic acid and glycolic acid (both alpha-hydroxy acids) instead of salicylic acid. The polyhydroxy acid used can be lactobionic acid or gluconolactone. Other acids that can be used are acids that have a net -1 charge as their main species in the final pH of the composition, such as glutamic acid or aspartic acid, but preservatives may be required in the composition. Polyacids such as maleic acid, oxalic acid, citric acid, EDTA, malic acid, tartaric acid, etc., and the compositions of the present invention may contain them to adjust the pH of the leave-on composition. In the present invention, combinations or mixtures of acids can be used. The present invention may contain polyacids, i.e., about 0.02% to about 0.2% citric acid, and may contain about 0.05% to about 0.1% acid.

[0051] Aqueous carrier

[0052] The hair care composition of the present invention comprises an aqueous carrier. The amount and type of the carrier are selected based on compatibility with other ingredients and other desired characteristics of the product.

[0053] In the present invention, the aqueous carrier can be substantially water. Deionized water can be used. Depending on the desired characteristics of the product, water from natural sources containing mineral cations can also be used. Typically, the compositions of the present invention contain from about 20% to about 99%, can be from about 30% to about 95%, and can be from about 80% to about 95% water.

[0054] diols

[0055] The hair care compositions of the present invention may include a dermatologically acceptable solvent. In the present invention, the carrier may include water and solutions or mixtures of water with lower alkyl alcohols and / or polyols. Examples of lower alkyl alcohols are monohydric alcohols having 1 to 6 carbon atoms, such as ethanol, methanol, propanol, isopropanol, butanol, pentanol, and hexanol. Examples of polyols are glycols, such as dipropylene glycol, propylene glycol, butylene glycol, 1,4-butylene glycol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butylene glycol, 1,3-propylene glycol, 2,2'-thiodiethanol, glycerol, and other glycols.

[0056] Other non-limiting examples of organic solvents include polyglycols, such as polypropylene glycol, polyethylene glycol, butanediol, polypropylene glycol, mixtures of polyethylene glycols; and ethers, such as dipropylene glycol n-butyl ether; sugars and sugar derivatives.

[0057] The compositions of the present invention may comprise propylene glycol and may comprise from about 1% to about 10%, or from about 1% to about 5%, of a solvent, or may comprise from about 2% to about 3% of a solvent.

[0058] Water-soluble polymers

[0059] The hair care composition of the present invention may also include a water-soluble polymer. When the total concentration of the lamellar gel phase is low, a hydrophobically modified polymer may be used to adjust the viscosity of the composition. The hydrophobically modified water-soluble polymer may have a naturally derived backbone such as, but not limited to, xanthan gum, cellulose, starch, guar gum, gellan gum, and the like, and combinations thereof. The water-soluble polymer may have a cationic charge. In the present invention, the water-soluble polymer may be polyquaternium-10, such as UCARE Extreme Polymer supplied by Dow Inc., or may be cetyl hydroxyethyl cellulose, such as Polysurf 67CS or Natrosol 330PLUS CS supplied by Ashland. Since the polymer itself has a high hydrophobicity, a polymer that can help restore the hydrophobicity of the hair surface may be used.

[0060] The compositions of the present invention may comprise from about 0.01% to about 0.5%, and may comprise from about 0.05% to about 0.25% of a water-soluble polymer.

[0061] Scalp Health Actives

[0062] In the present invention, scalp health actives can be added to provide scalp benefits. This group of actives is diverse and offers a wide range of benefits, including anti-dandruff, anti-fungal, anti-microbial, moisturizing, barrier-improving and antioxidant agents, anti-itch, and sensory agents. Such skin health actives and scalp care actives include, but are not limited to, zinc pyridone, climbazole, selenium sulfide, vitamins E and F, salicylic acid, glycols, glycolic acid, PCA, PEG, erythritol, glycerin, lactates, hyaluronates, allantoin and other ureas, betaines, sorbitol, glutamates, xylitol, menthol, menthyl lactate, isocyclic ketones, benzyl alcohol, and natural extracts / oils including peppermint, spearmint, arginine, jojoba oil, and aloe vera.

[0063] Optional ingredients

[0064] The composition of the present invention may further comprise any suitable optional ingredients as required. For example, the composition may optionally comprise other active ingredients or inactive ingredients.

[0065] The compositions may contain other common hair ingredients, such as other anti-dandruff actives, minoxidil, conditioning agents, and other suitable materials. The CTFA Cosmetic Ingredient Handbook, Tenth Edition (published by the Cosmetic, Toiletry, and Fragrance Association, Inc. (Washington, DC)) (2004) (hereinafter referred to as "CTFA") describes a wide variety of non-limiting materials that can be added to the compositions herein. Examples of these ingredient categories include, but are not limited to, abrasives, absorbents, aesthetic components such as fragrances, pigments, colorants / colorants, essential oils, skin sensates, astringents, and the like (e.g., clove oil, menthol, camphor, eucalyptus oil, eugenol, menthyl lactate, witch hazel distillate), anti-acne agents, anti-caking agents, defoaming agents, antimicrobial agents (e.g., iodopropyl butylcarbamate), niacinamide, antioxidants, binders, biological additives, buffers, extenders, chelating agents, chemical additives, colorants, cosmetic astringents, cosmetic pesticides, denaturants, pharmaceutical astringents, topical analgesics, film formers or film-forming materials such as polymers that contribute to the film-forming properties and substantivity of the composition (e.g., copolymers of eicosene and vinyl pyrrolidone), sunscreens, pH adjusters, propellants, reducing agents, sequestrants, rheology modifiers, hair conditioning agents, and surfactants.

[0066] acid

[0067] The hair care compositions of the present invention may comprise an acid. The acid may be used to control the pH of the composition within the desired range (3.5 to 6) since otherwise the pH may be above 7 due to the presence of the piroctone olamine salt.

[0068] fragrances

[0069] The compositions of the present invention may include a fragrance or a combination of fragrances. Some fragrances may include multiple fragrance ingredients. In particular, the fragrance may include hinokitiol, phenoxyethanol, and L-menthol. The composition may include only the amount of fragrance required to achieve the desired fragrance properties and intensity, but the amount of fragrance included should not be high enough to cause any material to act as a preservative in the composition.

[0070] Additional components

[0071] The compositions of the present invention may contain other additional components which may be selected by one skilled in the art based on the desired properties of the final product and which are suitable for rendering the compositions more cosmetically or aesthetically acceptable or for providing them with additional benefits. Such other additional components are typically used individually at levels of from about 0.001% to about 10%, and up to about 5%, by weight of the composition.

[0072] A variety of other additional components can be formulated into the compositions of the present invention. These additional components include: other conditioning agents, such as hydrolyzed collagen available under the trade name Peptein 2000 from Hormel, vitamin E available under the trade name Emix-d from Eisai, panthenol available from Roche, panthenyl ethyl ether available from Roche, hydrolyzed keratin, proteins, plant extracts, and nutrients; preservatives, such as benzyl alcohol, methylparaben, propylparaben, and imidazolidinyl urea; pH adjusters, such as citric acid, sodium citrate, succinic acid, phosphoric acid, sodium hydroxide, sodium carbonate; salts, generally such as potassium acetate and sodium chloride; colorants, such as any of the FD&C or D&C dyes; fragrances; and chelating agents, such as disodium EDTA; and ultraviolet and infrared screeners and absorbers, such as octylsalicylate.

[0073] In the present invention, the compositions of the present invention may be substantially free of preservatives. In the present invention, the compositions may be free of preservative compounds such as phenoxyethanol, benzyl alcohol, methylparaben, ethylparaben, and / or propylparaben. Although phenoxyethanol may be used as a fragrance at a level of up to 0.1% by weight of the composition, it cannot be used as a preservative at a level of at least 0.25% by weight of the composition.

[0074] In the present invention, the composition may be free of liquid oily compounds having an AlogP of ≥5.5.

[0075] Product form

[0076] The compositions of the present invention may be in the form of a leave-on or rinse-off product and may be formulated into a variety of product forms including, but not limited to, creams, gels, lotions, mousses, and sprays.

[0077] The composition of the present invention is particularly suitable for use in leave-in hair preparations. Such compositions can be used according to the following steps:

[0078] (i) applying an effective amount of a scalp benefit composition to the scalp and hair roots after shampooing and / or rinsing with a rinse-off conditioner; and

[0079] (ii) The hair is then not rinsed or rinsed.

[0080] Translucency

[0081] The hair care compositions of the present invention are transparent and may be translucent. The translucency of the composition may be preferred by consumers and may be a signal for application to the scalp, resulting in anti-dandruff benefits.

[0082] The composition of the present invention may have a viscosity of from about 0.01 Pa·s to about 10 Pa·s, and may be from about 5 Pa·s to about 10 Pa·s. Compositions with lower viscosities are more likely to be used by consumers on the scalp and are therefore more likely to produce anti-dandruff benefits.

[0083] Consumers may desire compositions of the present invention with minimal ingredients. The compositions may be formulated without polymeric thickeners or suspending agents such as carbomers, EGDS, or thixotropic agents. The compositions may contain 11 or fewer ingredients, 10 or fewer ingredients, 9 or fewer ingredients, 8 or fewer ingredients, 7 or fewer ingredients, or 6 or fewer ingredients. It will be understood that a fragrance may be formed from one or more materials.

[0084] Formulations and Examples

[0085] The following are non-limiting examples of the present invention. The examples are given for illustrative purposes only and should not be construed as limitations of the present invention, as many variations thereof are possible without departing from the spirit and scope of the present invention, as will be appreciated by those skilled in the art.

[0086] Preparation and handling protocols :

[0087] Preparation of no-wash treatment composition :

[0088] The leave-in treatment composition is prepared by adding piroctone olamine salt and glycol and spices (if necessary) to a nonionic surfactant / water carrier and stirring until completely dissolved. The solution pH is adjusted to a final pH of 4.0 to 6.0 using citric acid solution. Polymer (if necessary) is then added and the solution is mixed using a high-speed mixer at 1800 rpm to 2300 rpm for 2 to 5 minutes until a uniform composition is obtained.

[0089] Leave-in hair treatment solutions :

[0090] A 0.20 g amount of each composition of Examples I to IV was spread via syringe onto individual natural virgin brown hair switches weighing 2.0 g (dosage 0.10 g solution / g hair). The hair was allowed to air dry and then evaluated by a panel for tack / coating feel.

[0091] Evaluation Method

[0092] Hair switches treated with the leave-in treatment compositions were evaluated using the following method.

[0093] Hair Switch Stickiness Evaluation Method: The treated hair switches were kept at room temperature, laboratory conditions (32°C-35°C, 50% RH) for 2 hours, and then ten expert raters were asked to rate their respective hair stickiness based on a 5-point scale, with 5 being the highest (very sticky) and 1 being the lowest rating (not sticky).

[0094] Phase stability: The samples were stored in glass jars at room temperature (32°C to 35°C, 50% RH). Visible phase separation was recorded after 1 month. The presence of piroctone olamine salt crystals in the same samples was observed by microscopy with crossed polarizer filters (Keyence Digital Microscope VHX-7000 series). S = stable, U = unstable.

[0095] Clarity: Samples were scored for clarity on the day they were prepared. The panel rated the clarity of the formulations on a scale of 1 - opaque, 3 - translucent, and 5 - transparent.

[0096] Example

[0097] The following are non-limiting examples of the present invention. The following examples further describe and illustrate embodiments within the scope of the present invention. These examples are provided for illustrative purposes only and are not to be construed as limitations of the present invention, as many variations are possible without departing from the spirit and scope of the present invention. Applicable ingredients herein are identified by chemical name or CTFA name, unless otherwise specified below.

[0098] Table 1

[0099]

[0100]

[0101] 1 Oxymetholone, Clariant

[0102] 2 Dow

[0103] 3 Merck

[0104] 4 Twain 80, Croda

[0105] 5 Labbeemint,Inc

[0106] 6 Sigma Aldrich

[0107] 7 Jungbunzlauer Austria

[0108] 8 Supplied by Ineos Maastricht BV (Maastricht NL)

[0109] 9 Cargill

[0110] result Formulation Examples 1 to 4 exhibited clear, stable, and less viscous formulations at pH 5.5 to 5.8, while Example 5 was unstable due to high pH crystal formation, as evidenced by one day of formulation preparation. Examples 6 and 7 were unstable due to less solvent glycol for microemulsion formation and the absence of Tween 80, respectively. Example 8 was translucent after the addition of xanthan gum, while Examples 1 to 4 were transparent.

[0111] combination

[0112] A. A transparent hair care composition comprising a substituted 2-hydroxypyridine-N-oxide material; a glycol; a nonionic surfactant; a monocarboxylic acid or a polyacid; water or an aqueous carrier; wherein the composition has a pH of from about 3.5 to about 6.0; and wherein the composition is free of alcohol.

[0113] B. The transparent hair care composition according to paragraph A, wherein the nonionic surfactant has an HLB value of 10 to 15.

[0114] C. The transparent hair care composition of paragraphs A to B, comprising from about 1% to about 10% of a glycol selected from the group consisting of dipropylene glycol, propylene glycol, butylene glycol, 1,4-butylene glycol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butylene glycol, 1,3-propylene glycol, 2,2'-thiodiethanol, or glycerin.

[0115] D. A clear hair care composition according to paragraphs A to C, wherein the glycol is propylene glycol.

[0116] E. The transparent hair care composition according to paragraphs A to D, comprising from about 1% to about 15% of the nonionic surfactant, wherein the nonionic surfactant is selected from the group consisting of alkylphenol ethoxylates, polyethylene glycol / polypropylene glycol block copolymers, fatty alcohol and fatty acid ethoxylates, long chain tertiary amine oxides, long chain tertiary phosphine oxides, long chain dialkyl sulfoxides, alkyl polysaccharides or polyethylene glycol glycerol fatty acid esters, and mixtures thereof.

[0117] F. A transparent hair care composition according to paragraphs A to E, wherein the nonionic surfactant is Tween 80-polyoxyethylene (20) sorbitan monolaurate.

[0118] G. The clear hair care composition of paragraphs A to F, comprising from about 0.02% to about 0.2% of a monocarboxylic acid selected from the group consisting of alpha-hydroxy acids (AHAs), beta-hydroxy acids (BHAs), or polyhydroxy acids (PHAs), and mixtures thereof.

[0119] H. A clear hair care composition according to paragraphs A to G, wherein the polyacid is selected from the group consisting of maleic acid, oxalic acid, citric acid, EDTA, malic acid, or tartaric acid, and mixtures thereof.

[0120] I. The clear hair care composition of paragraphs A to H, wherein the polyacid is citric acid.

[0121] J. The clear hair care composition of paragraphs A to I, further comprising from about 0.01% to about 0.5% of a water-soluble polymer.

[0122] K. A clear hair care composition according to paragraphs A to J, wherein the water-soluble polymer has a naturally derived backbone selected from the group consisting of cellulose, starch, guar gum, or gellan gum, and mixtures thereof.

[0123] L. A clear hair care composition according to paragraphs A to K, wherein the water-soluble polymer is selected from the group consisting of polyquaternium-10 or cetyl hydroxyethylcellulose and mixtures thereof.

[0124] M. The clear hair care composition of paragraphs A to L, further comprising a scalp health active.

[0125] N. A clear hair care composition according to paragraphs A to M, wherein the composition is non-tacky and stable.

[0126] O. The clear hair care composition of paragraphs A to N, wherein the composition is free of anionic surfactants.

[0127] P. A clear hair care composition according to paragraphs A to O, wherein the composition consists of 9 ingredients or less.

[0128] Q. A transparent hair care composition according to paragraphs A to P, consisting of the following:

[0129] a.water;

[0130] b. Piroctone olamine salt;

[0131] c. Propylene glycol

[0132] d. Niacinamide;

[0133] e. Tween-80;

[0134] f.mosa mint oil;

[0135] g. panthenol;

[0136] h. citric acid; and

[0137] i. Benzyl alcohol.

[0138] R. A transparent hair care composition according to paragraphs A to Q, consisting of

[0139] a.water;

[0140] b. Piroctone olamine salt;

[0141] c. Propylene glycol

[0142] d. Niacinamide;

[0143] e. Tween-80;

[0144] f.mosa mint oil;

[0145] g. panthenol;

[0146] h. citric acid;

[0147] f. benzyl alcohol; and

[0148] jOptional spices.

[0149] It will be understood that other modifications may be made to this disclosure by one skilled in the art of hair care formulations without departing from the spirit and scope of the present invention. Unless otherwise indicated, all parts, percentages, and ratios herein are by weight. Some components may be obtained from suppliers as diluted solutions. Unless otherwise indicated, the levels given reflect the weight percentage of active material. Certain levels of fragrance and / or preservatives may also be included in the following examples.

[0150] The dimensions and values disclosed herein should not be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm."

[0151] Unless expressly excluded or otherwise limited, each document cited herein, including any cross-referenced or related patents or applications, is hereby incorporated by reference in its entirety. The citation of any document is not an admission that it is prior art with respect to any invention disclosed or claimed herein, nor is it an admission that it, alone or in any combination with any other reference or references, teaches, suggests, or discloses any such invention. In addition, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.

[0152] Although specific embodiments of the present invention have been illustrated and described, it will be apparent to those skilled in the art that various other changes and modifications may be made without departing from the spirit and scope of the invention. It is therefore intended that all such changes and modifications within the scope of the invention be encompassed in the appended claims.

Claims

1. A transparent hair care composition comprising: a) substituted 2-hydroxypyridine-N-oxide materials; b) diols; c) nonionic surfactants; d) a monocarboxylic acid or a polyacid; e) water or an aqueous carrier; wherein the composition has a pH of 3.5 to 6.0; and wherein the composition is free of alcohol.

2. The transparent hair care composition according to any one of the preceding claims, wherein the nonionic surfactant has an HLB value of 10 to 15.

3. A transparent hair care composition according to any one of the preceding claims, comprising 1% to 10% of a glycol selected from the group consisting of dipropylene glycol, propylene glycol, butylene glycol, 1,4-butylene glycol, 3-allyloxy-1,2-propanediol, 1,2-hexanediol, 1,6-hexanediol, 1,3-butylene glycol, 1,3-propanediol, 2,2'-thiodiethanol or glycerol, preferably wherein the glycol is propylene glycol.

4. A transparent hair care composition according to any one of the preceding claims, comprising 1% to 15% of a nonionic surfactant selected from the group consisting of alkylphenol ethoxylates, polyethylene glycol / polypropylene glycol block copolymers, fatty alcohol and fatty acid ethoxylates, long-chain tertiary amine oxides, long-chain tertiary phosphine oxides, long-chain dialkyl sulfoxides, alkyl polysaccharides or polyethylene glycol glycerol fatty acid esters and mixtures thereof, preferably wherein the nonionic surfactant is Tween 80-polyoxyethylene (20) sorbitan monolaurate.

5. A transparent hair care composition according to any one of the preceding claims, comprising from 0.02% to 0.2% of a monocarboxylic acid selected from the group consisting of alpha-hydroxy acids (AHAs), beta-hydroxy acids (BHAs) or polyhydroxy acids (PHAs) and mixtures thereof.

6. A transparent hair care composition according to any one of the preceding claims, wherein the polyacid is selected from the group consisting of maleic acid, oxalic acid, citric acid, EDTA, malic acid or tartaric acid and mixtures thereof, preferably wherein the polyacid is citric acid.

7. A clear hair care composition according to any preceding claim further comprising from 0.01% to 0.5% of a water-soluble polymer.

8. A transparent hair care composition according to any one of the preceding claims, wherein the water soluble polymer has a naturally derived backbone selected from the group consisting of cellulose, starch, guar gum or gellan gum and mixtures thereof.

9. The transparent hair care composition according to any of the preceding claims, wherein the water-soluble polymer is selected from the group consisting of polyquaternium-10 or cetyl hydroxyethylcellulose and mixtures thereof.

10. A clear hair care composition according to any preceding claim further comprising a scalp health active.

11. A clear hair care composition according to any one of the preceding claims, wherein the composition is non-sticky and stable.

12. A clear hair care composition according to any one of the preceding claims, wherein the composition is free of anionic surfactants.

13. A clear hair care composition according to any one of the preceding claims, wherein the composition consists of 9 ingredients or less.

14. A transparent hair care composition according to any one of the preceding claims, consisting of: a.water; b. Piroctone olamine salt; c. Propylene glycol d. Niacinamide; e. Tween-80; f.mosa mint oil; g. panthenol; h. citric acid; and i. Benzyl alcohol.

15. A transparent hair care composition according to any one of the preceding claims, consisting of: a.water; b. Piroctone olamine salt; c. Propylene glycol d. Niacinamide; e. Tween-80; f.mosa mint oil; g. panthenol; h. citric acid; i. Benzyl alcohol and j. Optional spices.

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