A collector for transnasal minimally invasive collection of trace cerebrospinal fluid of optic nerve
By designing a collection device for minimally invasive transnasal puncture, and utilizing a slender structure and an electric negative pressure device, efficient and accurate collection of optic nerve cerebrospinal fluid is achieved, overcoming the limitations of traditional lumbar puncture methods and reducing the difficulty and cost of operation.
Patent Information
- Application Number
- CN202510942943.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-07-09
- Publication Date
- 2025-11-04
- Estimated Expiration
- 2045-07-09
AI Technical Summary
Traditional lumbar puncture methods are difficult to use for direct collection of optic nerve cerebrospinal fluid, and the instruments are not suitable, resulting in inaccurate collection and operational difficulties.
Design a minimally invasive nasal aspirator, including a detachable reservoir tube, a suction connector, and an electric negative pressure device. Through a slender structure and a limiting tip, the optic nerve is minimally invasively cut open with a blade, and cerebrospinal fluid is aspirated using the electric negative pressure device and transferred to a reservoir via a siphon.
This method enables minimally invasive and precise cerebrospinal fluid collection, reducing operational difficulty and cost, improving collection efficiency, and minimizing fluid waste.
Smart Images

Figure CN120436689B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, specifically to a collector for minimally invasive nasal collection of a small amount of optic nerve cerebrospinal fluid. Background Technology
[0002] Optic nerve disorders are one of the leading causes of irreversible blindness. Optic neuropathy is a disease that affects the visual pathway, and its causes are diverse, including genetic factors, trauma, inflammation, infection, and tumors. The optic nerve is a crucial pathway for transmitting visual information from the eye to the brain; damage to it can lead to decreased vision or even blindness, severely impacting the patient's quality of life.
[0003] Cerebrospinal fluid (CSF) is a colorless, transparent fluid found in the ventricles, subarachnoid space, and around the spinal cord. Its main functions are to buffer and protect the central nervous system and maintain cerebral homeostasis. The optic nerve is enclosed by three layers of meninges (dura mater, arachnoid mater, and pia mater), forming the optic nerve sheath. The subarachnoid space extends to the periphery of the optic nerve and contains CSF, directly communicating with the intracranial subarachnoid space. Optic nerve diseases can cause localized changes in CSF. Therefore, the collection and analysis of CSF from the site of optic nerve lesions is of great significance for the diagnosis and treatment of optic nerve disorders.
[0004] However, traditional methods of obtaining cerebrospinal fluid (CSF) (such as lumbar puncture and other routine puncture methods) have certain limitations when applied to collecting CSF from the optic nerve. On the one hand, although the CSF obtained by lumbar puncture and the CSF around the optic nerve belong to the same circulatory system anatomically and physiologically, their compositions may differ due to their different locations. On the other hand, and most importantly, due to the narrow space around the optic nerve, the instruments used for lumbar puncture are not suitable for collecting CSF from the optic nerve area.
[0005] Therefore, this invention is proposed. Summary of the Invention
[0006] The purpose of this invention is to provide a device for collecting a small amount of optic nerve cerebrospinal fluid via a nasal minimally invasive procedure, so as to solve the technical problems existing in the prior art.
[0007] To achieve the above objectives, the technical solution adopted by the present invention is: a collector for collecting a small amount of optic nerve cerebrospinal fluid via nasal minimally invasive surgery, comprising: a collector body;
[0008] A liquid storage tube is detachably installed in the inner cavity of the collector body. The distal end of the liquid storage tube is detachably connected to a suction connector. A waterproof and breathable membrane is provided between the liquid storage tube and the suction connector. The suction connector is detachably connected to an electric negative pressure device.
[0009] The proximal end of the liquid storage tube is connected to a suction tube, which extends to the end of the collector body, and a limiting head end is arranged on the end.
[0010] A cutter head is mounted on the end, and the cutter tip of the cutter head protrudes out of the limiting head end along the axial direction of the collector body.
[0011] A push button is arranged on the collector body, and the push button is connected to the liquid storage tube. The push button can drive the liquid storage tube and the suction tube to move along the axial direction.
[0012] When the push button is in the first position, the suction head end of the suction tube is received between the cutter head and the limiting head end, and the suction head end does not protrude out of the limiting head end along the axial direction of the collector body.
[0013] When the push button is in the second position, the suction head end protrudes out of the cutter tip of the cutter head.
[0014] In an optional embodiment, a sliding groove is arranged on the collector body, and the push button moves along the sliding groove.
[0015] When the push button is close to one side of the suction connector along the sliding groove, the push button is in the first position, and when the push button is close to the other side of the cutter head along the sliding groove, the push button is in the second position.
[0016] The stroke of the push button moving along the sliding groove is not greater than 1.25 mm.
[0017] In an optional embodiment, the liquid storage tube comprises a main liquid storage cavity, a second guide cavity, and a first guide cavity arranged in sequence and in communication. The diameters of the main liquid storage cavity, the second guide cavity, and the first guide cavity decrease in sequence, and the first guide cavity is in communication with the suction tube.
[0018] In an optional embodiment, the suction tube is made of stainless steel, and the diameter of the suction tube is smaller than the diameter of the first guide cavity. The diameter of the suction tube is not greater than 0.5 mm.
[0019] In an optional embodiment, a limiting groove is arranged on the liquid storage tube, and the limiting groove is detachably connected to the push button. The limiting groove is located on the outer side wall of the first guide cavity close to the second guide cavity at one end of the liquid storage tube.
[0020] In an optional embodiment, a shearing groove is arranged on the liquid storage tube, and the shearing groove is located on the outer side wall of the first guide cavity away from the second guide cavity at one end of the liquid storage tube.
[0021] In an optional embodiment, the cutter head is provided with a cutter handle and a cutter blade, the cutter handle is mounted in the mounting part of the end, and the cutting edge of the cutter blade has a side cutting angle of at least 15°.
[0022] Optionally, a spring is arranged on the suction tube, one end of the spring abuts against the cavity wall of the collector body near the cutting head, and the other end of the spring abuts against one end of the liquid storage tube near the limiting head end.
[0023] Optionally, the limiting head end has an abutting surface and an inclined surface, the inclined surface extends from a top transition line to the abutting surface, the top transition line is a top line at the position of the maximum thickness of the middle part of the limiting head end, the inclination angle of the inclined surface is the same as the inclination angle of the cutting edge, and the cutting edge line of the cutting edge and the inclined surface are in the same plane.
[0024] Optionally, the liquid taking device detachably connected with the suction connector is further included.
[0025] The present application has the following advantages:
[0026] (1) The collector in the present application is applied to the surgery from the nasal cavity to the skull base, and the whole collector is elongated, so that the collector can extend from the nasal cavity to the skull base. When in use, the optic nerve is incised by the cutting head, the suction tube is extended by pushing the push button to the second position, and the cerebrospinal fluid is sucked into the liquid storage tube under the action of the electric negative pressure device. Then, the liquid storage tube is separated from the collector body, the waterproof and breathable membrane between the suction connector and the liquid storage tube is removed, the electric negative pressure device connected with the suction connector is replaced by the liquid taking device (a needle tube), the liquid storage tube is cut along the shearing groove on the liquid storage tube, the cut position of the liquid storage tube is aligned with the liquid storage device, and the cerebrospinal fluid in the liquid storage tube is transferred to the liquid storage device by pushing the liquid taking device (the needle tube) to generate positive pressure. The whole liquid taking process is efficient and accurate. After the optic nerve is accurately incised by the cutting head, the suction tube is extended to collect the cerebrospinal fluid by pushing the push button with one hand. Almost at the same time when the cerebrospinal fluid flows out, the cerebrospinal fluid is sucked into the liquid storage tube. Since the electric negative pressure device (which can only generate negative pressure) is used in the process of sucking the cerebrospinal fluid into the liquid storage tube, the operation of the collector can be realized by one hand, which reduces the operation difficulty. When the cerebrospinal fluid in the liquid storage tube is pushed out, since the pressure of the liquid taking device (the needle tube) is limited, the pressure generated by the liquid taking device (the needle tube) can be fully utilized to push the cerebrospinal fluid into the liquid storage device after the waterproof and breathable membrane is removed, which reduces the use cost.
[0027] (2) The blade of the collector in the present application is used for minimally invasive operation on the optic nerve. The blade penetrates into the optic nerve with a shallow depth (minimally invasive), and the wound on the optic nerve is small. The collector is also provided with a limiting head end. When the optic nerve is incised by the cutting head, the limiting head end abuts against the outside of the optic nerve, which can effectively prevent the cutting head from entering the optic nerve too much to cause additional damage to the patient.
[0028] (3) The diameter of the main liquid storage cavity, the second guide cavity and the first guide cavity of the collector in the application decreases in turn, the first guide cavity is communicated with the suction tube, the diameter of the suction tube is smaller than the diameter of the first guide cavity, and the diameter of the suction tube is not greater than 0.5 mm, so that the cerebral spinal fluid flowing out of the suction tube is reduced in the process of taking out the liquid storage tube together with the suction connecting piece and the suction tube connected therewith from the collector body and replacing the electric negative pressure device with a liquid taking device (a needle tube).
[0029] (4) The axis of the inclined pipe section of the suction tube and the axis of the horizontal pipe section of the suction tube form a certain angle, and the suction head end of the inclined pipe section is directed towards the direction of the blade tip, the axis of the inclined pipe section of the suction tube, the axis of the horizontal pipe section of the suction tube, the axis of the blade handle and the axis of the collector body are located in the same plane, the blade head does not rotate during the process of withdrawing the blade head a certain distance along the axial direction of the collector body, and the suction head end of the suction tube is inclined to the upper direction after being stretched out, so that the cerebral spinal fluid can be collected, the electric negative pressure device is used to work with the suction tube, the collection efficiency of the cerebral spinal fluid is improved, and the waste of the cerebral spinal fluid is reduced.
[0030] (5) The limiting head end of the collector has an inclined surface, the inclined surface extends from the top transition line to the abutment surface, the top transition line is the top line at the position where the thickness of the middle part of the limiting head end is the largest, the inclination angle of the inclined surface is the same as the inclination angle of the blade edge, the inclination angle of the inclined surface can be understood as the angle between the inclined surface and the axis of the collector body, and the blade edge line of the blade edge and the inclined surface are located in the same plane, so that the interference between the limiting head end and the optic nerve during the process of cutting or incising the optic nerve caused by the too large size or irregular shape of the limiting head end can be avoided, and the working efficiency of the blade head is improved. BRIEF DESCRIPTION OF DRAWINGS
[0031] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiments or the prior art description will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0032] Figure 1 The structure diagram of the collector (the suction tube is not stretched out) provided by an embodiment of the present application Figure 1 .
[0033] Figure 2 The structure diagram of the collector (the suction tube is not stretched out) provided by an embodiment of the present application Figure 2 .
[0034] Figure 3 The Figure 2 cutting plane view of A-A in the application.
[0035] Figure 4 Fig. 1 is a schematic view of a collecting device according to the present application. Figure 3 Fig. 2 is a schematic view of a detail A of Fig. 1.
[0036] Figure 5 Fig. 3 is a schematic view of a detail B of Fig. 1. Figure 3 Fig. 4 is a schematic view of a detail B of Fig. 1.
[0037] Figure 6 Fig. 5 is a schematic view of a collecting device according to an embodiment of the present application.
[0038] Figure 7 Fig. 6 is a schematic view of a detail C of Fig. 1. Figure 6 Fig. 7 is a schematic view of a section B-B of Fig. 1.
[0039] Figure 8 Fig. 8 is a schematic view of a detail C of Fig. 1. Figure 7 Fig. 9 is a schematic view of a section C-C of Fig. 1.
[0040] Figure 9 Fig. 10 is a schematic view of a collecting device according to an embodiment of the present application.
[0041] Figure 10 Fig. 11 is a schematic view of a detail D of Fig. 1. Figure 9 Fig. 12 is a schematic view of a section D-D of Fig. 1.
[0042] Figure 11 Fig. 13 is a schematic view of a collecting device according to an embodiment of the present application.
[0043] Figure 12 Fig. 14 is a schematic view of a detail D of Fig. 1. Figure 11 Fig. 15 is a schematic view of a section D-D of Fig. 1.
[0044] Figure 13 Fig. 16 is a schematic view of a collecting device according to an embodiment of the present application. Figure 3 .
[0045] Figure 14 Fig. 17 is a schematic view of a detail D of Fig. 1. Figure 13 . Figure 1 .
[0046] Figure 15 Fig. 18 is a schematic view of a detail D of Fig. 1. Figure 13 Fig. 19 is a schematic view of a section D-D of Fig. 1. Figure 2 .
[0047] Wherein, the reference signs are: 1 - tool head, 11 - tool handle, 12 - blade, 13 - cutting edge, 14 - tool tip; 2 - collector body, 21 - abutting point, 22 - sliding groove, 23 - mounting portion, 24 - limit head end, 241 - inclined surface, 242 - abutting surface, 243 - side cross section, 244 - top transition line; 3 - push button; 4 - liquid storage tube, 41 - main liquid storage cavity, 42 - second guide cavity, 43 - first guide cavity, 44 - limiting groove, 45 - shearing groove; 5 - suction connector; 6 - waterproof breathable membrane; 7 - sealing ring; 8 - spring; 9 - suction tube, 91 - suction head end; 10 - liquid extractor. DETAILED DESCRIPTION
[0048] In order to make the technical problems to be solved by the present application, technical solutions and beneficial effects more clearly, the present application will be further described in detail below in combination with the drawings and examples. It should be understood that the specific examples described herein are only used to explain the present application and do not limit the present application.
[0049] It should be noted that when a component is referred to as "fixed to" or "pasted" to another component, it can be directly or indirectly on the other component. When a component is referred to as "connected to" another component, it can be directly or indirectly connected to the other component. The terms "up", "down", "left", "right", "front", "back", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate the orientation or position based on the orientation or position shown in the drawings, and are only for convenience of description, and cannot be understood as a limitation on the technical solutions. The terms "first", "second" are only for the purpose of convenient description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features. The meaning of "a plurality of" is two or more, and the meaning of "several" is any number including one, unless otherwise explicitly specified.
[0050] Please refer to the accompanying Figures 1-15The embodiment aims to provide a collector for collecting trace cerebrospinal fluid of optic nerve through minimally invasive nasal approach, which comprises a collector body 2, the diameter of the collector body 2 is not greater than 10 mm, so that the collector is in an elongated shape, facilitating the collector to reach the optic nerve and complete the surgery. A liquid storage tube 4 is detachably installed in the inner cavity of the collector body 2, the distal end of the liquid storage tube 4 is detachably connected with a suction connector 5, a waterproof and breathable film 6 is arranged between the liquid storage tube 4 and the suction connector 5, and the suction connector 5 is detachably connected with an electric negative pressure device. In an optional embodiment, the waterproof and breathable film 6 is a circular film, which is located at one end of the liquid storage tube 4 close to the electric negative pressure device, and the diameter is preferably 6 mm. Liquid molecules cannot pass through the film, but gas molecules can pass through. The liquid sucked by the suction tube 9 enters the liquid storage tube 4, and when passing through the waterproof and breathable film 6, the gas is sucked into the electric negative pressure device, and the liquid is left in the liquid storage tube 4. The waterproof and breathable film 6 is made of a high polymer material and is treated by a special process to ensure that it has good chemical resistance and biocompatibility, which can effectively prevent the collected liquid from being contaminated.
[0051] Specifically, the proximal end of the liquid storage tube 4 is connected with the suction tube 9, the suction tube 9 extends to the end of the collector body 2, and a limiting head end 24 is arranged on the end. A cutter head 1 is installed on the end, the cutter tip 14 of the cutter head 1 protrudes out of the limiting head end 24 in the axial direction of the collector body 2. When the cutter head 1 is used to cut the optic nerve, the limiting head end 24 abuts against the outside of the optic nerve, which can effectively prevent the cutter head 1 from entering the optic nerve too much and causing additional damage.
[0052] It is worth mentioning that a push button 3 is arranged on the collector body 2, the push button 3 is connected with the liquid storage tube 4, and the push button 3 can drive the liquid storage tube 4 and the suction tube 9 to move in the axial direction. When the push button 3 is in the first position, the suction head end 91 of the suction tube 9 is accommodated between the cutter head 1 and the limiting head end 24, and the suction head end 91 does not protrude out of the limiting head end 24 in the axial direction of the collector body 2. When the push button 3 is in the second position, the suction head end 91 protrudes out of the cutter tip 14 of the cutter head 1. It should be pointed out that a sliding groove 22 is arranged on the collector body 2, and the push button 3 moves along the sliding groove 22. When the push button 3 is close to the side of the suction connector 5 along the sliding groove 22, the push button 3 is in the first position. When the push button 3 is close to the side of the cutter head 1 along the sliding groove 22, the push button 3 is in the second position. The stroke of the push button 3 moving along the sliding groove 22 is not greater than 1.25 mm. In the embodiment, a resting point 21 is further arranged on the collector body 2, which is located on the left side of the push button 3. When the user pushes the push button 3, the resting point 21 can provide a support force point for the hand, facilitating the use of the collector.
[0053] Further, the liquid storage tube 4 comprises a main liquid storage cavity 41, a second guide cavity 42 and a first guide cavity 43 which are sequentially communicated, the diameters of the main liquid storage cavity 41, the second guide cavity 42 and the first guide cavity 43 sequentially decrease, and the first guide cavity 43 is communicated with the suction tube 9. The liquid storage tube 4 is 3D printed by using polylactic acid material, which not only has good biocompatibility, but also ensures the lightness and strength of the device. The suction tube 9 is made of stainless steel, the diameter of the suction tube 9 is smaller than that of the first guide cavity 43, and the diameter of the suction tube 9 is not greater than 0.5 mm. In the process of replacing the electric negative pressure device with the liquid taking device 10 (a needle tube) after the liquid storage tube 4 together with the suction connection piece 5 and the suction tube 9 connected therewith is taken out of the collector body 2, the cerebrospinal fluid flowing out of the suction tube 9 is reduced (mainly due to the effect of the sequentially decreasing diameters). One end of the suction tube 9 is directly connected with the liquid storage tube 4 in the 3D printing process, and the high-precision 3D printing technology is used to ensure the sealing and stability of the connection.
[0054] It should be noted that when the collector body 2 is horizontally placed, the suction tube 9 has a horizontal tube segment and an inclined tube segment, the suction head end 91 located at the inclined tube segment faces the direction of the knife tip 14 and partially abuts the inner surface of the limiting head end 24, and preferably, the included angle between the axis of the inclined tube segment of the suction tube 9 and the axis of the horizontal tube segment thereof is 15° (the axis of the inclined tube segment of the suction tube 9, the axis of the horizontal tube segment and the axis of the shank of the knife head 1, and the axis of the collector body 2 are located in the same plane), and the inclined tube segment of the suction tube 9 is preferably the same as the side cutting angle of the knife edge 13. Through the above arrangement, after the knife head 1 is withdrawn a certain distance along the axial direction of the collector body 2 (the knife head 1 and the collector body 2 do not rotate), the suction head end 91 of the suction tube 9 is inclined to the obliquely upward direction after being stretched out (the push button 3 is in the second position), and the suction head end 91 can complete the collection of cerebrospinal fluid when abutting the surface of the optic nerve. The suction tube 9 cooperates with the electric negative pressure device to work, thereby improving the collection efficiency of cerebrospinal fluid and reducing the waste of cerebrospinal fluid.
[0055] In the embodiment, the liquid storage tube 4 is provided with a limiting groove 44, and the limiting groove 44 is connected with the push button 3. The limiting groove 44 is located outside the side wall of the first guide cavity 43 of the liquid storage tube 4 close to the second guide cavity 42. The liquid storage tube 4 is provided with a shearing groove 45, and the shearing groove 45 is located outside the side wall of the first guide cavity 43 of the liquid storage tube 4 away from the second guide cavity 42.
[0056] In addition, the cutter head 1 is provided with a cutter handle 11 and a cutter blade 12, and the cutter handle 11 is installed in the mounting portion 23 of the end head. Preferably, the cutter head 1 is made of 30Cr13 material, which has excellent strength and corrosion resistance, can withstand high load during surgery and effectively prolong the service life of the cutter blade 12. The cutting edge 13 of the cutter blade 12 has at least a side cutting angle of 15°, which can accurately cut and reduce damage to the surrounding tissue of the optic nerve when performing optic nerve decompression, thereby effectively draining the cerebrospinal fluid in the optic nerve and promoting the relief of the pressure around the optic nerve.
[0057] In an optional embodiment, the limiting head end 24 has an abutting surface 242 for abutting the outside of the optic nerve when the cutter head 1 is used to pierce the optic nerve. The abutting surface 242 is a curved surface that can prevent damage to the optic nerve when it comes into contact with the optic nerve. It should be noted that the limiting head end 24 has a bevel 241 extending from the top transition line 244 to the abutting surface 242. The top transition line 244 is the top line at the position where the thickness of the limiting head end 24 is the largest. The inclination angle of the bevel 241 is the same as the inclination angle of the cutting edge 13 (the inclination angle of the bevel 241 can be understood as the angle between the bevel 241 and the axis of the collector body 2), and the cutting edge line of the cutting edge 13 is in the same plane as the bevel 241. This can avoid interference between the limiting head end 24 and the optic nerve during the process of cutting or incising the optic nerve caused by the excessive size or irregular shape of the limiting head end 24. Specifically, referring to FIG. 4, it is assumed that the limiting head end 24 extends from the top transition line 244 to the abutting surface 242, and the cross section of the limiting head end 24 further includes a side cutting cross section 243. During the process of piercing the optic nerve with the cutter head 1, the part of the limiting head end 24 with the side cutting cross section 243 will interfere with the insertion of the cutter head 1 into the optic nerve, for example, when the cutter head 1 is used obliquely. However, the shape of the limiting head end 24 (with the bevel 241) shown in FIG. 4 can avoid the above interference. Figure 15 Figure 14
[0058] Finally, the suction tube 9 is provided with a spring 8, one end of the spring 8 abuts against the cavity wall of the collector body 2 near the cutter head 1, and the other end of the spring 8 abuts against one end of the liquid storage tube 4 near the limiting head end 24. After the operation is completed, the suction tube 9 can rebound to the initial position under the action of the spring 8, so that the push button 3 automatically moves from the second position to the first position.
[0059] When the collector is used to collect cerebrospinal fluid of the optic nerve, the following steps are performed:
[0060] S1: expose the optic nerve by surgery, connect the electric negative pressure device to the suction connector 5, use the cutter head 1 to cut the optic nerve, and the limiting head end 24 of the cutter head 1 abuts against the outside of the optic nerve membrane; at this time, the push button 3 is in the first position;
[0061] S2: move the cutter head 1 to outside of the optic nerve membrane, and then push the push button 3 to the second position, so that the suction head end 9 of the suction tube 9 is attached to the surface of the optic nerve membrane;
[0062] S3: after the cerebrospinal fluid in the optic nerve membrane flows out, the electric negative pressure device is started to suck the cerebrospinal fluid into the storage tube 4;
[0063] S4: the storage tube 4 is taken out of the collector body 2 together with the suction connector 5 and the suction tube 9 connected thereto, at this time, the push button 3 needs to be disconnected from the storage tube 4; then the waterproof and breathable film 6 between the suction connector 5 and the storage tube 4 is removed; and the electric negative pressure device connected with the suction connector 5 is replaced by the liquid taking device 10;
[0064] S5: the storage tube 4 is cut along the cutting groove 45 on the storage tube 4, and the cut position of the storage tube 4 is aligned with the storage device, and the liquid taking device 10 is pushed to generate positive pressure to transfer the cerebrospinal fluid in the storage tube 4 to the storage device.
[0065] The whole liquid taking process is convenient and efficient, especially in the process of sucking the cerebrospinal fluid into the storage tube 4, since the electric negative pressure device (only negative pressure can be generated) is used, one-handed operation of the collector can be realized, and the operation difficulty is reduced; when the cerebrospinal fluid in the storage tube 4 is pushed out, since the pressure of the liquid taking device 10 (a needle tube) is limited, after the waterproof and breathable film 6 is removed, the pressure generated by the liquid taking device 10 (a needle tube) can be fully utilized to push the cerebrospinal fluid into the storage device, and the use cost is reduced. The collector is not only suitable for cerebrospinal fluid collection of human patients, but also can be used for animal experiments, especially in the diagnosis and research of traumatic optic neuropathy, intracranial pressure abnormalities and other diseases, and has important application value.
[0066] The above is only a preferred embodiment of the present application, and is not used to limit the present application, any modification, equivalent replacement and improvement within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A collector for transnasal minimally invasive collection of micro quantities of cerebrospinal fluid of optic nerve, characterized in that, The utility model relates to a kind of suction devices, including: Collector body (2); Detachable liquid storage tube (4) is installed in the inner cavity of the collector body (2), the distal end of the liquid storage tube (4) is detachably connected with suction connector (5), waterproof and breathable membrane (6) is arranged between the liquid storage tube (4) and the suction connector (5), and the suction connector (5) is detachably connected with electric negative pressure device; The proximal end of the liquid storage tube (4) is connected with suction tube (9), the suction tube (9) extends to the end of the collector body (2), and a limiting head end (24) is arranged on the end. A cutter head (1) is mounted on the end, and the cutter tip (14) of the cutter head (1) protrudes out of the limiting head end (24) in the axial direction of the collector body (2). A push button (3) is arranged on the collector body (2), the push button (3) is connected with the liquid storage tube (4), and the push button (3) can drive the liquid storage tube (4) and the suction tube (9) to move in the axial direction thereof. When the push button (3) is in the first position, the suction head end (91) of the suction tube (9) is received between the cutter head (1) and the limiting head end (24), and the suction head end (91) does not protrude out of the limiting head end (24) in the axial direction of the collector body (2). When the push button (3) is in the second position, the suction head end (91) protrudes out of the cutter tip (14) of the cutter head (1). The limiting head end (24) has an abutting surface (242) and an inclined surface (241), the inclined surface (241) extends from a top transition line (244) to the abutting surface (242), the top transition line (244) is a top end line at a position where the thickness of the limiting head end (24) is maximum, the inclination angle of the inclined surface (241) is the same as the inclination angle of the cutting edge (13), and the cutting edge line of the cutting edge (13) and the inclined surface (241) are in the same plane.
2. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 1, wherein A sliding groove (22) is arranged on the collector body (2), and the push button (3) moves along the sliding groove (22). When the push button (3) is close to one side of the suction connector (5) along the sliding groove (22), the push button (3) is in the first position, and when the push button (3) is close to one side of the cutter head (1) along the sliding groove (22), the push button (3) is in the second position. The stroke of the push button (3) moving along the sliding groove (22) is not greater than 1.25 mm.
3. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 2, wherein The liquid storage tube (4) comprises a main liquid storage cavity (41), a second guide cavity (42) and a first guide cavity (43) arranged in sequence, the diameters of the main liquid storage cavity (41), the second guide cavity (42) and the first guide cavity (43) decrease in sequence, and the first guide cavity (43) is communicated with the suction tube (9).
4. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 3, wherein The suction tube (9) is made of stainless steel, the diameter of the suction tube (9) is smaller than the diameter of the first guide cavity (43), and the diameter of the suction tube (9) is not greater than 0.5 mm.
5. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 4, wherein The liquid storage pipe (4) is provided with a limiting groove (44), which is detachably connected with the push button (3); the limiting groove (44) is located outside the side wall of the first guide cavity (43) of the liquid storage pipe (4) near one end of the second guide cavity (42).
6. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 4, wherein The liquid storage pipe (4) is provided with a shearing groove (45), which is located outside the side wall of the first guide cavity (43) of the liquid storage pipe (4) away from one end of the second guide cavity (42).
7. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 1, wherein The cutter head (1) is provided with a cutter handle (11) and a cutter blade (12), the cutter handle (11) is installed in the mounting portion (23) of the end head; the cutting edge (13) of the cutter blade (12) has at least a side cutting angle of 15°.
8. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 1, wherein The suction pipe (9) is provided with a spring (8), one end of the spring (8) abuts against the cavity wall of the inner cavity of the collector body (2) near the cutter head (1), and the other end of the spring (8) abuts against one end of the liquid storage pipe (4) near the limiting head end (24).
9. The collector for transnasally minimally invasively collecting a trace amount of cerebrospinal fluid of the optic nerve according to claim 1, wherein Further comprising a liquid taking device (10) detachably connected with the suction connector (5).
Citation Information
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