A microfluidics-based pellet production device

Abstract

The present application relates to the technical field of drop pill production equipment, and discloses a drop pill production equipment based on microfluidics, including a drop control board assembly, an attached charge assembly, a drop pill output assembly, and a pill weight screening assembly. The drop control board assembly has a drop flow channel, the attached charge assembly is located at the end of the drop flow channel, the drop pill output assembly and the drop control board assembly are spaced apart, thereby forming a screening gap between the drop pill output assembly and the drop control board assembly, and the pill weight screening assembly is located within the screening gap. The pill weight screening assembly is used to screen the weight of the medicinal liquid passing through the screening gap. The medicinal liquid that does not meet the weight requirements will be directly discharged from the screening gap to the outside of the drop pill production equipment, thereby improving the weight consistency of the drop pills produced by the drop pill production equipment.

Description

Technical Field

[0001] The present invention relates to the technical field of dropping pill production equipment, and in particular to a dropping pill production equipment based on microfluidics. Background Art

[0002] Dropping pills are a type of rapid-release drug, primarily produced through a melt-drip-condensation process. Currently, available dropping pill production equipment mixes different liquid drugs, drips the mixed liquid, and cools the dripped liquid to form a droplet output.

[0003] However, the pill making equipment on the market is unable to screen the quality of the pills during the making process, resulting in poor weight consistency of the pills made by the pill making equipment. Summary of the Invention

[0004] In order to address the deficiencies of the prior art, the purpose of the present application is to provide a microfluidics-based pellet production device, which has the function of screening the quality of the pellets to improve the weight consistency of the pellets produced by the pellet production device.

[0005] A microfluidic-based droplet pill production device includes a droplet control board component, an attached charge component, a droplet pill output component, and a pill weight screening component. The droplet control board component has a droplet flow channel, and the droplet flow channel has multiple input ports for inputting different liquid medicines and multiple output ports for outputting mixed liquid medicines; the attached charge component is installed at the output port, and under the action of the attached charge component, the mixed medicine at the output port is attached with an electric charge to form a charged liquid medicine; the droplet pill output component is arranged on one side of the output port, and a screening gap is provided between the droplet pill output component and the droplet control board component. The component has a pill output channel, the center of the opening of the pill output channel toward the drop control board assembly is at the same height as the center of the output port, and the pill output assembly also has an output magnetic field; the pill weight screening assembly is located in the screening gap, and the pill weight screening assembly has a screening magnetic field; wherein, the screening magnetic field exerts a screening force on the charged liquid medicine, and the direction of the screening force is opposite to the direction of gravity of the charged liquid medicine; and, the output magnetic field exerts a conveying force on the charged liquid medicine, and the direction of the conveying force is parallel to the line connecting the center of the opening of the pill output channel toward the drop control board assembly and the center of the output port.

[0006] Furthermore, the pill weight screening assembly includes a first baffle and a second baffle, wherein the position of the first baffle is higher than the position of the output port, and the position of the second baffle is lower than the position of the output port.

[0007] Furthermore, the pill weight screening assembly also includes a suction pipe with a plurality of suction ports formed thereon. The suction ports extend toward the lower end surface of the first baffle, and there is a gap between the suction ports and the side wall of the first baffle facing the suction ports.

[0008] Furthermore, the first baffle is tilted relative to the vertical direction of the drip control plate assembly, and the height of the first baffle toward the suction port is higher than the height of the first baffle away from the suction port;

[0009] The second baffle is substantially parallel to the first baffle.

[0010] Furthermore, the two ends of the first baffle are respectively connected to the dripping control board assembly and the dripping pill output assembly; the two ends of the second baffle are respectively connected to the dripping control board assembly and the dripping pill output assembly.

[0011] Furthermore, the dripping channel includes a mounting cavity and a dripping output channel, and the end of the dripping output channel facing the dripping pill output component forms an output port; the mounting cavity is connected to the dripping output channel, and the attached charge component is installed in the mounting cavity.

[0012] Furthermore, the dripping channel also includes a mixing channel and multiple input channels, each input channel is formed with multiple branch channels, and in the height direction of the dripping control plate assembly, the mixing channel is connected to the branch channels of adjacent input channels located at the same height.

[0013] Furthermore, the input channel includes a converging channel and a plurality of branch channels, and the plurality of branch channels are communicated with the converging channel.

[0014] Furthermore, the plane where the input channel is located is parallel to the end face of the drip control board assembly; the plane where the mixing channel is located is perpendicular to the drip control board assembly, and parallel to the line connecting the opening center of the drip output channel toward the drip control board assembly and the center of the output port.

[0015] Furthermore, the pill output assembly includes an output plate and a collecting box. The pill output channel is arranged in the output plate, and the collecting box is arranged at the end of the pill output channel away from the pill output assembly.

[0016] By setting a pill weight screening component in the screening gap between the drip control board component and the pill output component, the pills can be screened according to weight during the pill making process, so as to improve the weight consistency of the pills made by the pill making equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a structural schematic diagram of the pill making equipment according to the embodiment of the present application.

[0018] Figure 2 yes Figure 1 A partial enlarged view of point A of the pellet making equipment shown.

[0019] Figure 3 yes Figure 1 Schematic diagram of the screening magnetic field and output magnetic field of the dropping pill making device shown, wherein the dropping pill making device is hidden in this schematic diagram.

[0020] Figure 4 yes Figure 1 The schematic diagram of the structure of the pill making equipment after it is rotated at a certain angle.

[0021] Figure 5 yes Figure 1 The schematic diagram of the structure of the dripping control board assembly of the dripping pill making equipment shown.

[0022] Figure 6 yes Figure 5 A vertical cross-sectional view of the drip control plate assembly is shown.

[0023] Figure 7 yes Figure 5 A transverse cross-sectional view of the drip control plate assembly is shown.

[0024] Figure 8 yes Figure 1 The schematic diagram of the structure of the attached charge component of the dripping pill production equipment shown, wherein the dotted area is the projection of the dripping flow channel on the bottom plate in a top view.

[0025] Figure 9 yes Figure 1 Schematic diagram of the structure of the output plate of the pill making equipment shown.

[0026] Figure markings: drop control plate assembly 1, drop flow channel 1-1, input port 1-1-1, output port 1-1-2, mounting cavity 1-1-3, drop output channel 1-1-4, mixing channel 1-1-5, input channel 1-1-6, branch channel 1-1-7, confluence channel 1-1-8, attached charge assembly 2, attached charge electrode sheet 2-1, bottom plate 2-2, mixing electrode 2-3, conveying electrode 2-4, pill output assembly 3, pill output channel 3-1, first channel 3-1-1, second channel 3-1-2, output plate 3-2, collecting box 3-3, output magnetic field 3-4, screening gap 4, pill weight screening assembly 5, screening magnetic field 5-2, first baffle 5-3, second baffle 5-4, straw 5-5, suction port 5-5-1, first magnetic field generator 5-6, second magnetic field generator 5-7. DETAILED DESCRIPTION

[0027] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the specific implementation of the present application will be clearly and completely described below in conjunction with the drawings in the implementation of the present application.

[0028] Due to the small size of the droplets, existing drop pill production equipment is unable to screen the drop pills during the production process, resulting in poor weight consistency of the drop pills output from the drop pill production equipment. To ensure the weight consistency of the drop pills, a weight screening step must be added after the drop pills are produced, increasing the production cost of the drop pills. At the same time, because the drop pill production equipment does not have a weight screening function, the drop pills that do not meet the weight requirements must complete the entire drop pill production process within the drop pill production equipment, reducing the production efficiency of the drop pill production equipment.

[0029] like Figure 1 As shown, the pill production apparatus of this embodiment includes a liquid drop control panel assembly 1, a charge attachment assembly 2, a pill output assembly 3, and a pill weight screening assembly 5. The liquid drop control panel assembly 1 has a liquid drop channel 1-1, which is used to mix different liquid medicines and output the mixed liquid medicines to the liquid drop control panel assembly 1. The charge attachment assembly 2 is located at the end of the liquid drop channel 1-1 and is used to attach a charge to the liquid medicine output from the liquid drop channel 1-1. The pill output assembly 3 is spaced apart from the liquid drop control panel assembly 1, that is, a screening gap 4 is defined between the pill output assembly 3 and the liquid drop control panel assembly 1. The pill weight screening assembly 5 is located within the screening gap 4. The pill weight screening assembly 5 performs weight screening on the liquid medicines passing through the screening gap 4. Liquid medicines that do not meet the weight requirements are discharged directly from the screening gap 4 to the outside of the pill production apparatus, thereby improving the weight consistency of the pills produced by the pill production apparatus.

[0030] In order to clearly illustrate the technical solution of this application, it is also defined Figure 1 In this application, the height direction refers to Figure 1 The up and down directions in .

[0031] Among them, Figure 2 、 Figure 3 and Figure 4 As shown, the drip channel 1-1 has an input port 1-1-1 and an output port 1-1-2, wherein the liquid medicine flows into the drip channel 1-1 through the input port 1-1-1 for mixing, and the mixed liquid medicine is output outside the drip control board assembly 1 through the output port 1-1-2.

[0032] The charge-attaching component 2 is installed at the output port 1-1-2. After the mixed liquid flows through the charge-attaching component 2, the mixed liquid is charged by the charge-attaching component 2 to form a charged liquid.

[0033] The pill output component 3 is located on one side of the output port 1-1-2, and the pill output component 3 is spaced apart from the output port 1-1-2, thereby forming a screening gap 4 between the pill output component 3 and the drop control board component 1. The medicinal liquid is output from the output port 1-1-2, passes through the screening gap 4, and moves into the pill output component 3, and then is cooled by the pill output component 3 to form pills.

[0034] Furthermore, the pill output assembly 3 includes a pill output channel 3-1, the opening center of the pill output channel 3-1 facing the drop control board assembly 1 is located at the same height as the center of the output port 1-1-2. The pill output assembly 3 also has an output magnetic field 3-4, the direction of the output magnetic field 3-4 is as follows: Figure 3 As shown by the double-dotted line, the output magnetic field 3-4 applies a conveying force to the charged medicinal liquid, and the direction of the conveying force is parallel to the line connecting the opening center of the droplet output channel 3-1 toward the droplet control board assembly 1 and the center of the output port 1-1-2, that is, the conveying force is used to convey the medicinal liquid output from the output port 1-1-2 into the droplet output channel 3-1.

[0035] As an implementation method, the number of pill output channels 3-1 is consistent with the number of output ports 1-1-2, and the pill output channels 3-1 correspond one to one with the output ports 1-1-2. Furthermore, in the same height plane, the number of pill output channels 3-1 is consistent with the number of output ports 1-1-2, and one pill output channel 3-1 is arranged opposite one output port 1-1-2.

[0036] The pill weight screening component 5 is located in the screening gap 4. The pill weight screening component 5 has a screening magnetic field 5-2. The direction of the screening magnetic field 5-2 is as follows: Figure 3 As shown by the dotted lines, the screening magnetic field 5-2 exerts a screening force on the charged liquid, and the direction of the screening force is opposite to the direction of gravity of the charged liquid. When the screening force is equal to the gravity of the charged liquid, the charged liquid moves within the screening gap 4 without any upward or downward deviation, so that after the charged liquid is output from the output port 1-1-2, it moves through the screening gap 4 to the pill output channel 3-1. The charged liquid is cooled by the pill output component 3 to form pills before being output. When the screening force is not equal to the gravity of the charged liquid, the charged liquid moves within the screening gap 4 with an upward or downward deviation, making it unable to move into the pill output channel 3-1. The charged liquid is discharged from the pill production equipment through the screening gap, achieving weight screening of the charged liquid and improving the consistency of the weight of the pills output by the output pill production equipment.

[0037] As a way to implement Figure 2 and Figure 3 As shown, the pill weight screening assembly 5 includes a first magnetic field generator 5-6 and a second magnetic field generator 5-7, which are respectively located at the upper and lower sides of the screening gap 4. The first magnetic field generator 5-6 and the second magnetic field generator 5-7 form a screening magnetic field 5-2 within the screening gap 4 through the first magnetic field generator 5-6 and the second magnetic field generator 5-7, so that the charged liquid medicine is subjected to a screening force within the screening gap 4. Specifically, the first magnetic field generator 5-6 and the second magnetic field generator 5-7 can be strong magnets or electromagnets.

[0038] It should be noted that the screening magnetic field 5 - 2 is a uniform magnetic field, and the screening force exerted on the same charged liquid at different positions of the screening magnetic field 5 - 2 is consistent.

[0039] As an implementation, pill weight screening assembly 5 includes a first baffle 5-3 and a second baffle 5-4. The first baffle 5-3 is positioned above the output port 1-1-2, while the second baffle 5-4 is positioned below the output port 1-1-2. The first baffle 5-3 and the second baffle 5-4 ensure that the liquid medicine output from the output port 1-1-2 only flows into the pill output channel 3-1 at the same height, thereby further improving the consistency of the pill weight outputted by the pill production apparatus.

[0040] Specifically, when the gravity of the charged medicine liquid is less than the screening force, the medicine liquid moves upward under the action of the screening force, so that the medicine liquid moves to the lower end surface of the first baffle 5-3, thereby preventing the medicine liquid from being mistakenly received by the higher droplet output channel 3-1; or, when the gravity of the charged medicine liquid is greater than the screening force, the medicine liquid moves downward under the action of its gravity, so that the medicine liquid moves to the upper end surface of the second baffle 5-4, thereby preventing the medicine liquid from being mistakenly received by the lower droplet output channel 3-1.

[0041] It should be noted that each outlet 1-1-2 corresponds to a first baffle 5-3 and a second baffle 5-4, ensuring that the liquid medicine output from each outlet 1-1-2 flows only into the pill output channel 3-1 at the corresponding height. Furthermore, the second baffle 5-4 at the upper outlet 1-1-2 can function as the first baffle 5-3 at the adjacent lower outlet 1-1-2.

[0042] As an implementation method, the pill weight screening component 5 also includes a suction pipe 5-5, and a plurality of suction ports 5-5-1 are formed on the suction pipe 5-5. The suction ports 5-5-1 extend toward the lower end surface of the first baffle 5-3, and there is a gap between the suction ports 5-5-1 and the side wall of the first baffle 5-3 toward the suction ports 5-5-1. The medicine liquid below the first baffle 5-3 is sucked through the suction ports 5-5-1, so that the lighter medicine liquid can be stably recovered and prevented from floating in the screening magnetic field 5-2.

[0043] Specifically, multiple suction ports 5-5-1 are located at different heights to facilitate the recovery of lighter liquid medicine output from output ports 1-1-2 at different heights. Furthermore, since the weight of the charged liquid medicine varies, it moves to different locations on the lower end surface of the first baffle 5-3. By providing multiple suction ports 5-5-1 at the same height and distributing the multiple suction ports 5-5-1 along the extension direction of the first baffle 5-3, liquid medicines of different weights can be sucked, thereby facilitating the recovery of liquid medicines of different weights.

[0044] As an implementation method, in order to further facilitate the recovery of the medicine whose weight is less than the screening force through the suction tube 5-5, the first baffle 5-3 is tilted relative to the vertical direction of the drop control plate assembly 1, and the height of the first baffle 5-3 toward the suction port 5-5-1 is higher than the height of the first baffle 5-3 away from the suction port 5-5-1, so that the medicine whose weight is less than the screening force moves toward the suction port 5-5-1 under the guidance of the first baffle 5-3.

[0045] As an implementation method, the second baffle 5-4 is basically parallel to the first baffle 5-3, so that the medicinal liquid with a weight greater than the screening force moves in the direction away from the suction port 5-5-1 under the guidance of the second baffle 5-4, so that the medicinal liquid with a weight greater than the screening force falls outside the pill making equipment under the action of its gravity.

[0046] By setting the first baffle 5-3 and the second baffle 5-4 at an angle, it is convenient to separately process the medicinal liquid whose weight is greater than the screening force and the medicinal liquid whose weight is less than the screening force, so as to stably output the medicinal liquid whose weight is not equal to the screening force out of the present drop pill making equipment, and prevent the medicinal liquid of unqualified weight from interfering with the movement of subsequent medicinal liquid, thereby improving the operating stability of the drop pill making equipment.

[0047] As an implementation method, the two ends of the first baffle 5-3 are connected to the liquid drop control board assembly 1 and the pill output assembly 3, respectively; the two ends of the second baffle 5-4 are connected to the liquid drop control board assembly 1 and the pill output assembly 3, respectively. This ensures that the liquid medicine can only move within the channel formed by the first baffle 5-3 and the second baffle 5-4, preventing the liquid medicine from being mistakenly received by the pill output channel 3-1 at a different height, further improving the consistency of the pill weight output by the output pill production device.

[0048] As a way to implement Figure 5 、 Figure 6 and Figure 7As shown, the dripping channel 1-1 includes multiple dripping output channels 1-1-4, a mixing channel 1-1-5, and multiple input channels 1-1-6. The input channels 1-1-6 are connected to the mounting cavity 1-1-3 through the mixing channel 1-1-5. The end of the dripping output channel 1-1-4 facing the pill output assembly 3 forms an output port 1-1-2. Different liquid medicines are transported to the mixing channel 1-1-5 through the input channel 1-1-6, where they are mixed and then output from the dripping channel 1-1 through the output port 1-1-2 of the dripping output channel 1-1-4.

[0049] In this embodiment, the dripping channel 1-1 is described as including three input channels 1-1-6, sixteen mixing channels 1-1-5, and sixteen dripping output channels 1-1-4. It should be noted that the number of input channels 1-1-6, mixing channels 1-1-5, and dripping output channels 1-1-4 in the dripping pill production equipment can be adjusted according to actual production requirements.

[0050] In this implementation, the planes of the three input channels 1-1-6 are parallel to the end faces of the parallel droplet control plate assembly 1, and each input channel 1-1-6 includes a confluence channel 1-1-8 and multiple branch channels 1-1-7. Multiple branch channels 1-1-7 are connected to the confluence channel 1-1-8, and an input port 1-1-1 is formed at the end of the confluence channel 1-1-8 away from the branch channel 1-1-7. The branch channels 1-1-7 are connected to the confluence channel 1-1-8. Specifically, sixty branch channels 1-1-7 are formed at the ends of the input channels 1-1-6.

[0051] The plane where the mixing channel 1-1-5 is located is perpendicular to the drip control board assembly 1, and parallel to the line connecting the center of the opening of the drip output channel 1-1-4 toward the drip control board assembly 1 and the center of the output port 1-1-2, that is, the plane where the mixing channel 1-1-5 is located is parallel to the horizontal plane and the height direction of the drip control board assembly 1, and each mixing channel 1-1-5 is respectively connected to the branch channel 1-1-7 of the adjacent input channel 1-1-6 located at the same height, so that the drugs input by the three input channels 1-1-6 are mixed in the mixing channel 1-1-5.

[0052] The dripping liquid output channel 1-1-4 is connected to the end of the mixing channel 1-1-5, so that the mixed liquid can be outputted out of the dripping flow channel 1-1 through the output channel 1-1-4. The multiple branch channels 1-1-7 are provided to increase the mixing and output of the liquid, thereby increasing the number of pills produced in a single batch and improving the production efficiency of the pill production equipment.

[0053] As an implementation method, the dripping channel 1-1 also includes a mounting cavity 1-1-3, which is located above or below the dripping output channel 1-1-4. The mounting cavity 1-1-3 is connected to the dripping output channel 1-1-4. The charge attachment component 2 is installed in the mounting cavity 1-1-3. The charge attachment component 2 attaches charges to the liquid medicine in the dripping output channel 1-1-4, forming a charged liquid medicine. By arranging the mounting cavity 1-1-3 within the dripping control board assembly 1, it is ensured that the charge attachment component 2 can stably attach a fixed amount of charge to the mixed liquid medicine, thereby facilitating the screening magnetic field 5-2 of the pill weight screening assembly 5 to screen the liquid medicine according to its weight, thereby improving the weight consistency of the pills produced by the pill production equipment.

[0054] As a way to implement Figure 8 As shown, the attached charge assembly 2 includes an attached charge electrode sheet 2-1, which is disposed at the end of the droplet output channel 1-1-4 near the output port 1-1-2. A high-voltage direct current or pulse voltage is applied to the attached charge electrode sheet 2-1. When the high-voltage direct current is applied to the attached charge electrode sheet 2-1, the charge is attached to the liquid medicine through contact charging. When the pulse voltage is applied to the attached charge electrode sheet 2-1, the charge is attached to the liquid medicine through induction charging.

[0055] It should be noted that the charge-attaching electrode sheet 2 - 1 works in a pulsed manner, that is, the charge-attaching electrode sheet 2 - 1 works once to attach charge to the drug solution once, and the amount of charge attached to the drug solution each time is fixed.

[0056] As an implementation, the charge attachment component 2 includes a base plate 2-2, the base plate 2-2 is installed in the installation cavity 1-1-3, and the charge attachment electrode sheet 2-1 is integrated on the base plate 2-2.

[0057] As an implementation method, the attached charge component 2 also includes at least two mixing electrodes 2-3 integrated on the bottom plate 2-2. The mixing electrodes 2-3 are located in the mixing channel 1-1-5, and the two mixing electrodes 2-3 are respectively arranged at positions close to the inner walls on both sides of the mixing channel 1-1-5. When an AC electric field is applied to the two mixing electrodes 2-3, the drug solution is deformed, vibrated or rotated due to the action of dielectric force, thereby disturbing the drug solution and mixing the drug solution.

[0058] As another implementation method, a hydrophobic area is formed on the bottom plate 2-2, the hydrophobic area is located in the mixing channel 1-1-5, and multiple mixing electrodes 2-3 are distributed in an array in the hydrophobic area. A voltage is applied to the mixing electrode 2-3 to change the hydrophilicity and hydrophobicity of the local hydrophobic area, causing the drug solution to deform and oscillate, thereby achieving drug solution mixing.

[0059] As an implementation, the mounting cavity 1-1-3 extends to the mixing channel 1-1-5, so that the bottom plate 2-2 extends to the bottom of the mixing channel 1-1-5, thereby facilitating the mixing electrode 2-3 to extend into the mixing channel 1-1-5.

[0060] As an implementation method, the bottom plate 2-2 includes an insulating area, which is located between the charge electrode 2-1 and the mixing electrode 2-3. A plurality of delivery electrodes 2-4 are provided in the insulating area along the delivery direction of the liquid medicine. A voltage is applied to each delivery electrode 2-4 in turn, so that the contact angle of the delivery electrode 2-4 at the voltage-applied portion decreases, thereby causing the liquid medicine to spread toward the energized electrode, thereby achieving the movement of the liquid medicine from the mixing electrode 2-3 to the attached charge electrode sheet 2-1.

[0061] As a way to implement Figure 4 As shown, the pill output assembly 3 includes an output plate 3-2 and a collecting box 3-3. The pill output channel 3-1 is arranged in the output plate 3-2, and the collecting box 3-3 is arranged at the end of the pill output channel 3-1 away from the pill output assembly 3. The pills output from the pill output channel 3-1 are collected by the collecting box 3-3.

[0062] As a way to implement Figure 9 As shown, the pill output channel 3-1 includes a first channel 3-1-1 and a second channel 3-1-2 that are interconnected. The center line of the first channel 3-1-1 is located on the same straight line as the center of the output port 1-1-2. The second channel 3-1-2 is tilted downward toward the collection box 3-3, and the pills are guided into the collection box 3-3 through the second channel 3-1-2.

[0063] As an implementation, a cooling element (not shown) is provided on the side wall of the output plate 3-2. The cooling element cools the output plate 3-2, thereby lowering the temperature of the output plate 3-2 and causing the liquid medicine to solidify and form pills within the pill output channel 3-1. Specifically, the cooling element can be a component with a cooling function, such as a semiconductor refrigeration chip.

[0064] As an implementation method, the pill output assembly 3 further includes a third magnetic field generator, which is used to generate an output magnetic field 3-4, so that the charged liquid medicine is moved into the first channel 3-1-1 under the action of the output magnetic field 3-4. Specifically, the third magnetic field generator can be a strong magnet or an electromagnet.

[0065] It should be noted that the output magnetic field 3 - 4 is a uniform magnetic field, that is, the conveying force exerted on the same charged liquid at different positions of the output magnetic field 3 - 4 is consistent.

[0066] Finally, it should be noted that the above are only some of the preferred implementation methods of the present application and are not intended to limit the present application. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned implementation methods or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims

1. A microfluidic-based pellet production device, characterized in that: include: A drip control panel assembly (1), the drip control panel assembly (1) having a drip flow channel (1-1), the drip flow channel (1-1) having a plurality of input ports (1-1-1) for inputting different liquid medicines and a plurality of output ports (1-1-2) for outputting mixed liquid medicines; An attached charge component (2), the attached charge component (2) being installed at the output port (1-1-2), and under the action of the attached charge component (2), the mixed medicine at the output port (1-1-2) is attached with electric charges to form a charged medicine liquid; A pill output assembly (3), the pill output assembly (3) being arranged on one side of the output port (1-1-2), and having a screening gap (4) between the pill output assembly (3) and the drop control board assembly (1), the pill output assembly (3) having a pill output channel (3-1), the center of the opening of the pill output channel (3-1) toward the drop control board assembly (1) being located at the same height as the center of the output port (1-1-2), and the pill output assembly (3) further having an output magnetic field (3-4); a pill weight screening component (5), the pill weight screening component (5) being located in the screening gap (4), and the pill weight screening component (5) having a screening magnetic field (5-2); wherein the screening magnetic field (5-2) exerts a screening force on the charged liquid, and the direction of the screening force is opposite to the direction of gravity of the charged liquid; Furthermore, the output magnetic field (3-4) exerts a conveying force on the charged liquid medicine, and the direction of the conveying force is parallel to a line connecting the center of the opening of the dripping control board assembly (1) and the center of the output port (1-1-2) toward the dripping pill output channel (3-1).

2. The microfluidics-based pellet production device according to claim 1, characterized in that: The pill weight screening assembly (5) comprises a first baffle (5-3) and a second baffle (5-4); the position of the first baffle (5-3) is higher than the position of the output port (1-1-2), and the position of the second baffle (5-4) is lower than the position of the output port (1-1-2).

3. The microfluidics-based pellet production device according to claim 2, characterized in that: The pill weight screening assembly (5) further comprises a suction pipe (5-5), wherein a plurality of suction ports (5-5-1) are formed on the suction pipe (5-5), wherein the suction ports (5-5-1) extend toward the lower end surface of the first baffle (5-3), and a gap is formed between the suction ports (5-5-1) and a side wall of the first baffle (5-3) facing the suction ports (5-5-1).

4. The microfluidic-based pellet production device according to claim 3, characterized in that: The first baffle (5-3) is tilted relative to a direction perpendicular to the drip control plate assembly (1), and the height of the first baffle (5-3) toward the suction port (5-5-1) is higher than the height of the first baffle (5-3) away from the suction port (5-5-1); The second baffle (5-4) is substantially parallel to the first baffle (5-3).

5. The microfluidics-based pellet production device according to claim 2, characterized in that: The two ends of the first baffle (5-3) are respectively connected to the drip control board assembly (1) and the drip pill output assembly (3); the two ends of the second baffle (5-4) are respectively connected to the drip control board assembly (1) and the drip pill output assembly (3).

6. The microfluidics-based pellet production device according to claim 1, characterized in that: The dripping flow channel (1-1) comprises a mounting cavity (1-1-3) and a dripping output channel (1-1-4), and the end of the dripping output channel (1-1-4) facing the dripping pill output component (3) forms the output port (1-1-2); The installation cavity (1-1-3) is in communication with the droplet output channel (1-1-4), and the attached charge component (2) is installed in the installation cavity (1-1-3).

7. The microfluidics-based pellet production device according to claim 6, characterized in that: The dripping flow channel (1-1) further comprises a mixing channel (1-1-5) and a plurality of input channels (1-1-6), each of the input channels (1-1-6) being formed with a plurality of branch channels (1-1-7), and in the height direction of the dripping control plate assembly (1), the mixing channel (1-1-5) is connected to the branch channels (1-1-7) of the adjacent input channels (1-1-6) located at the same height.

8. The microfluidics-based pellet production device according to claim 7, characterized in that: The input channel (1-1-6) includes a converging channel (1-1-8) and a plurality of branch channels (1-1-7), and the plurality of branch channels (1-1-7) are in communication with the converging channel (1-1-8).

9. The microfluidics-based pellet production device according to claim 7, characterized in that: The plane where the input channel (1-1-6) is located is parallel to the end surface of the drip control plate assembly (1); The plane where the mixing channel (1-1-5) is located is perpendicular to the drip control plate assembly (1), and parallel to a line connecting the center of the opening of the drip output channel (1-1-4) toward the drip control plate assembly (1) and the center of the output port (1-1-2).

10. The microfluidics-based pellet production device according to claim 1, characterized in that: The pill output assembly (3) comprises an output plate (3-2) and a collection box (3-3); the pill output channel (3-1) is arranged in the output plate (3-2); and the collection box (3-3) is arranged at the end of the pill output channel (3-1) away from the pill output assembly (3).

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