Traditional Chinese medicine compound with lipid-lowering and blood-pressure-lowering effects and preparation method of traditional Chinese medicine compound

Through decoction and precipitation treatment of combinations of traditional Chinese medicines such as Shenghongqu, safe and effective Chinese medicine compound prescriptions were prepared, which solved the problem of side effects of Western medicine and achieved safe improvements to hyperlipidemia and hypertension.

CN120459237AInactive Publication Date: 2025-08-12徐向太
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Patent Information

Application Number
CN202510817734.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-18
Publication Date
2025-08-12
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing Western medicines have side effects such as liver and kidney function damage and muscle pain when treating hypertension and hyperlipidemia, and lack safe and effective solutions for Chinese medicine.

Method used

The combination of traditional Chinese medicines such as raw red quor, gypsum blue, hawthorn, astragalus, salvia miltiorrhiza, albicans, corn squid, summer squid, polygonatum, coix seed, polygonatum, squid, and cassia seed are prepared through decoction and precipitation treatment in specific steps to prepare a Chinese medicine compound prescription with lowering lipid and blood pressure.

Benefits of technology

It effectively improves hyperlipidemia and hypertension symptoms, and does not damage liver and kidney function and muscle function, and has significant lipid-lowering and blood pressure lowering effects.

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Abstract

The invention discloses a traditional Chinese medicine compound with lipid-lowering and blood-pressure-lowering effects, and relates to the field of traditional Chinese medicine preparations. The traditional Chinese medicine compound comprises the following raw materials in parts by weight: monarch drugs: 12-30g of raw red yeast rice and 9-20g of gynostemma pentaphylla; ministerial drugs: one or more of 12-30 g of clean hawthorn, 15-60 g of astragalus membranaceus, 12-30 g of salvia miltiorrhiza and 12-30 g of rhizoma alismatis; assistant and guide drugs: one or more of 9-20 g of corn stigma, 12-30 g of selfheal, 12-30 g of prepared rhizoma polygonati, 20-60 g of semen coicis, 12-30 g of prepared polygonum multiflorum, 9-20 g of polygonum cuspidatum and 9-20 g of semen cassiae; the traditional Chinese medicine compound with the lipid-lowering and blood-pressure-lowering effects is reasonable in formula, can effectively improve the symptoms of hyperlipidemia and hypertension, and has no damage to liver and kidney functions and muscle functions.
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Description

Technical Field

[0001] The present invention relates to a Chinese medicine preparation technology, and in particular to a Chinese medicine compound with lipid-lowering and blood pressure-lowering effects and a preparation method thereof. Background Art

[0002] Traditional Chinese medicine (TCM) refers to medications used under the guidance of Traditional Chinese Medicine (TCM) theory. These medicines are primarily derived from natural products and their processed products, including plants, animals, and minerals. They emphasize a holistic approach and treatment based on syndrome differentiation, focusing on regulating the body's yin and yang balance. They are characterized by multi-component, multi-target, and holistic regulation. TCM demonstrates unique advantages in treating chronic diseases, sub-health conditions, and disease recovery. In clinical practice, TCM is often combined with other therapies, such as acupuncture and massage, to form comprehensive treatment plans. Furthermore, with the advancement of modern science and technology, the research and development of TCM is gradually becoming more scientific, standardized, and internationalized. As a vital carrier of traditional Chinese culture, TCM carries a rich historical and cultural heritage. Its inheritance and development must balance the preservation of traditional knowledge with the integration of modern science and technology.

[0003] Hypertension is a clinical syndrome characterized by elevated systemic arterial pressure, usually referring to systolic blood pressure ≥140 mmHg and / or diastolic blood pressure ≥90 mmHg measured three times on different days without the use of antihypertensive drugs. The symptoms of this disease are diverse. In the early stages, there may be no obvious discomfort. Some patients may experience symptoms such as headache, dizziness, palpitations, tinnitus, or blurred vision. However, hypertension is often called a "silent killer" because many patients may develop damage to organs such as the heart, brain, and kidneys without symptoms, leading to serious complications such as stroke, myocardial infarction, or renal failure. The onset of hypertension is closely related to genetic factors, unhealthy lifestyles (such as a high-salt diet, excessive alcohol consumption, lack of exercise, and long-term mental stress), aging, and other diseases (such as diabetes and kidney disease).

[0004] Hyperlipidemia, also known as hyperlipidemia or dyslipidemia, refers to elevated levels of triglycerides and (or) total cholesterol in plasma, which may be accompanied by elevated low-density lipoprotein cholesterol and decreased high-density lipoprotein cholesterol. There are usually no obvious symptoms in the early stages of the disease, and some patients may develop skin xanthomas, premature corneal rings, or fundus changes. As the disease progresses, patients may feel fatigue, chest pain, or shortness of breath. The onset of hyperlipidemia is related to genetic factors, poor eating habits (such as high-fat, high-sugar diets), lack of exercise, obesity, smoking, excessive drinking, and other diseases (such as diabetes, nephrotic syndrome, liver disease). Hyperlipidemia is an important risk factor for cardiovascular disease, which may lead to atherosclerosis, and then cause serious health problems such as coronary heart disease, stroke, and peripheral arterial disease.

[0005] Hyperlipidemia and hypertension often occur together in cardiovascular diseases, and existing Western medicines have side effects such as liver and kidney damage and muscle pain. Summary of the Invention

[0006] The purpose of the present invention is to provide a Chinese herbal compound with lipid-lowering and blood pressure-lowering effects and a preparation method thereof, so as to solve the above-mentioned deficiencies in the prior art.

[0007] In order to achieve the above object, the present invention provides the following technical solution: a Chinese herbal compound with lipid-lowering and blood pressure-lowering effects, the raw materials of which include, by weight:

[0008] Main herbs: raw red yeast rice 12-30g and Gynostemma pentaphyllum 9-20g;

[0009] Assistant herbs: clean hawthorn 12-30g, astragalus 15-60g, salvia miltiorrhiza 12-30g and oriental rhizome 12-30g;

[0010] Auxiliary drugs: corn silk 9-20g, selfheal 12-30g, processed polygonatum 12-30g, coix seed 20-60g, processed polygonum multiflorum 12-30g, knotweed 9-20g, cassia seed 9-20g.

[0011] Furthermore, the main medicines include 15g of raw red yeast rice and 15g of Gynostemma pentaphyllum;

[0012] The auxiliary drugs include 20g of Hawthorn, 30g of Astragalus, 20g of Salvia miltiorrhiza and 20g of Alisma orientalis;

[0013] The adjuvant drugs include corn silk 9g, selfheal 21g, processed polygonatum 20g, coix seed 40g, processed polygonum multiflorum 12g, polygonum cuspidatum 14g, and cassia seed 12g.

[0014] Furthermore, the main medicines include 12g of raw red yeast rice and 12g of Gynostemma pentaphyllum;

[0015] The auxiliary medicines include 30g of pure hawthorn and 30g of salvia miltiorrhiza;

[0016] The adjuvant drugs include 20g of processed Polygonatum sibiricum and 9g of Polygonum cuspidatum.

[0017] Furthermore, the main medicines include 15g of raw red yeast rice and 15g of Gynostemma pentaphyllum;

[0018] The auxiliary drugs include 30g of Hawthorn, 20g of Salvia miltiorrhiza and 15g of Alisma orientalis;

[0019] The adjuvant drugs include 15g of corn silk, 30g of selfheal, 20g of processed polygonatum, 20g of processed polygonatum, 12g of knotweed and 9g of cassia seed.

[0020] The preparation method of a traditional Chinese medicine compound having lipid-lowering and blood pressure-lowering effects is applicable to the traditional Chinese medicine compound described above, comprising the following steps:

[0021] S1. Selecting, by weight, the main drugs: raw red yeast rice and gynostemma pentaphyllum, the auxiliary drugs: one or more of clean hawthorn, astragalus, salvia miltiorrhiza, and oriental rhizome, and the adjuvant drugs: one or more of corn silk, selfheal, processed polygonatum, coix seed, processed polygonum multiflorum, knotweed, and cassia seed as the medicinal materials, and then washing the medicinal materials in sequence;

[0022] S2. Place the cleaned medicinal materials in an open space to dry naturally, and then place the naturally dried medicinal materials in a dry and clean container and weigh them;

[0023] S3, placing the medicinal materials prepared in proportion in a pot and mixing, then adding cold water, and then stirring by physical methods, heating to boiling over high heat after mixing, then decocting over low heat for 30-45 minutes, filtering out the medicinal residue, and obtaining the first drug filtrate;

[0024] S4, adding water twice to the medicinal residue in S3, decocting and boiling for 25-35 minutes over a slow fire, and filtering out the medicinal residue to obtain a secondary medicinal filtrate;

[0025] S5. Combine the first drug filtrate obtained in S3 and the second drug filtrate obtained in S4, and then let it settle to allow the drug residue to completely precipitate. Take the supernatant of the precipitated drug solution to obtain a traditional Chinese medicine compound with lipid-lowering and blood pressure-lowering effects.

[0026] Furthermore, in said S3, the high heat is to maintain a firepower of 100±5°C before boiling, and the low heat is to maintain a slightly boiling state of 80±5°C after boiling.

[0027] Compared with the existing technology, the Chinese herbal compound with lipid-lowering and blood pressure-lowering effects and the preparation method thereof provided by the present invention have a reasonable formula, can effectively improve the symptoms of hyperlipidemia and hypertension, and have no damage to liver, kidney and muscle functions. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments described in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0029] Figure 1 This is a flow chart of the preparation method provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0030] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0031] Example 1:

[0032] A Chinese herbal compound with lipid-lowering and blood pressure-lowering effects, the raw materials of which include, by weight:

[0033] Main herbs: raw red yeast rice 12-30g and Gynostemma pentaphyllum 9-20g;

[0034] Assistant herbs: clean hawthorn 12-30g, astragalus 15-60g, salvia miltiorrhiza 12-30g and oriental rhizome 12-30g;

[0035] Auxiliary drugs: corn silk 9-20g, selfheal 12-30g, processed polygonatum 12-30g, coix seed 20-60g, processed polygonum multiflorum 12-30g, knotweed 9-20g, cassia seed 9-20g.

[0036] Example 2:

[0037] The main herbs include 15g of red yeast rice and 15g of Gynostemma pentaphyllum;

[0038] The auxiliary drugs include 20g of Hawthorn, 30g of Astragalus, 20g of Salvia miltiorrhiza and 20g of Alisma orientalis;

[0039] The adjuvant drugs include corn silk 9g, selfheal 21g, processed polygonatum 20g, coix seed 40g, processed polygonum multiflorum 12g, polygonum cuspidatum 14g, and cassia seed 12g.

[0040] Example 3:

[0041] The main herbs include 12g of red yeast rice and 12g of Gynostemma pentaphyllum;

[0042] The auxiliary medicines include 30g of pure hawthorn and 30g of salvia miltiorrhiza;

[0043] The adjuvant drugs include 20g of processed Polygonatum sibiricum and 9g of Polygonum cuspidatum.

[0044] Example 4:

[0045] The main herbs include 15g of red yeast rice and 15g of Gynostemma pentaphyllum;

[0046] The auxiliary drugs include 30g of Hawthorn, 20g of Salvia miltiorrhiza and 15g of Alisma orientalis;

[0047] The adjuvant drugs include 15g of corn silk, 30g of selfheal, 20g of processed polygonatum, 20g of processed polygonatum, 12g of knotweed and 9g of cassia seed.

[0048] Embodiment 5:

[0049] The preparation method of a Chinese herbal compound having lipid-lowering and blood pressure-lowering effects is applicable to the above-mentioned Chinese herbal compound, comprising the following steps:

[0050] S1. Selecting, by weight, the main drugs: raw red yeast rice and gynostemma pentaphyllum, the auxiliary drugs: one or more of clean hawthorn, astragalus, salvia miltiorrhiza, and oriental rhizome, and the adjuvant drugs: one or more of corn silk, selfheal, processed polygonatum, coix seed, processed polygonum multiflorum, knotweed, and cassia seed as the medicinal materials, and then washing the medicinal materials in sequence;

[0051] S2. Place the cleaned medicinal materials in an open space to dry naturally, and then place the naturally dried medicinal materials in a dry and clean container and weigh them;

[0052] S3, placing the medicinal materials prepared in proportion in a pot and mixing, then adding cold water, and then stirring by physical methods, heating to boiling over high heat after mixing, then decocting over low heat for 30-45 minutes, filtering out the medicinal residue, and obtaining the first drug filtrate;

[0053] S4, adding water twice to the medicinal residue in S3, decocting and boiling for 25-35 minutes over a slow fire, and filtering out the medicinal residue to obtain a secondary medicinal filtrate;

[0054] S5. Combine the first drug filtrate obtained in S3 and the second drug filtrate obtained in S4, and then let it settle to allow the drug residue to completely precipitate. Take the supernatant of the precipitated drug solution to obtain a traditional Chinese medicine compound with lipid-lowering and blood pressure-lowering effects.

[0055] In the S3, the high heat is to maintain a firepower of 100±5°C before boiling, and the low heat is to maintain a slightly boiling state of 80±5°C after boiling.

[0056] Example 6:

[0057] Patient name: Zheng Moumou, male, age 61 years old;

[0058] Examination showed: total cholesterol 6.47mmol / L, low-density lipoprotein cholesterol 3.38mmol / L, serum apolipoprotein A1 1.88g / L, serum apolipoprotein B 1.36g / L, glycosylated hemoglobin 7.4%, lymphocyte count 3.88×10^9 / L;

[0059] Treatment options:

[0060] Select 15g of raw red yeast rice, 15g of Gynostemma pentaphyllum, 20g of clean hawthorn, 30g of astragalus, 20g of salvia miltiorrhiza, 20g of oriental rhizome, 9g of corn silk, 21g of selfheal, 20g of processed polygonatum, 40g of coix seed, 12g of processed polygonum multiflorum, 14g of polygonum cuspidatum, 12g of cassia seed, 9g of bamboo shavings, 12g of shelled amomum villosum, 12g of kudzu flower, 12g of stir-fried atractylodes with honey bran, 15g of white peony root, 9g of French pinellia, 20g of white poria, 30g of iris, 15g of daidaihua, 12g of dried tangerine peel, 20g of stir-fried trichosanthes peel, 6g of liquorice slices, 12g of epimedium, and 20g of stir-fried cuttlebone. Prepare the medicine by concentrated decoction with water according to the preparation method. Take one dose orally per day.

[0061] Re-inspection on April 5, 2025:

[0062] Physical examination: temperature: 36.7 degrees, pulse: 76 beats / min, respiration: 18 breaths / min, blood pressure: 141 / 83 mmHg, moderate body shape, normal development, average nutrition, clear consciousness, good spirits, plain complexion, good reaction, moderate voice, normal respiration, no distension of the abdomen, no tenderness or rebound pain in the upper abdomen, pain on pressing of the waist, pale tongue with slightly yellow coating, thin and wiry pulse.

[0063] Auxiliary examination: Routine color Doppler ultrasound examination (abdomen (including liver, gallbladder, pancreas, spleen)) The examination report showed: mild fatty liver.

[0064] The test report showed: glucose 6.3 mmol / L; urea 3.5 mmol / L; high-density lipoprotein 1.86 mmol / L; A / GI I 1.6; alanine aminotransferase 6 U / L.

[0065] TCM diagnosis: accumulation disease;

[0066] Western medicine diagnosis: fatty liver;

[0067] TCM Syndrome Differentiation: Phlegm-dampness blocking the body;

[0068] TCM treatment method: Activate blood circulation and remove blood stasis, eliminate phlegm and clear turbidity;

[0069] After the compound treatment, the overall therapeutic effect of patient Zheng Moumou showed a positive improvement trend, and many key indicators recovered well. Total cholesterol dropped from 6.47mmol / L to the normal range, low-density lipoprotein cholesterol was 3.38mmol / L, and glycated hemoglobin dropped from 7.4% to the normal range, indicating that blood sugar control was significantly improved. Overall, the current formula has a clear control effect on blood lipids and blood sugar.

[0070] Patient name: Qian Moumou, female, age 67 years old;

[0071] Physical examination: body temperature: 36.5 degrees, pulse: 80 beats / min, respiration: 16 breaths / min, blood pressure: 133 / 84 mmHg, normal development, good nutrition, clear consciousness, independent posture, relaxed expression, cooperative during physical examination, relevant answers, moderate body shape, acceptable complexion, red tongue with smooth coating, and thready, wiry pulse.

[0072] Auxiliary examination: The discharge report from the Pudong District People's Hospital of Shanghai, affiliated to the Pudong People's Hospital of Tongji University, in October 2023 showed: Discharge diagnosis: 1. Ischemic cerebrovascular disease; 2. Cerebral artery stenosis; 3. Hyperlipidemia; 4. Hyperuricemia; 5. Cervical disc herniation; 6. Lumbar disc herniation; 7. Fatty liver; 8. Vitamin D deficiency; 9. Thyroid nodules; 10. Personal history of cerebral infarction;

[0073] Hepatitis B, syphilis, HIV: HBcAb 15.2CO I, glycosylated hemoglobin 6.6, uric acid 442; blood lipids: triglycerides 2.63, total cholesterol 5051, high-density lipoprotein cholesterol 1.15, low-density lipoprotein cholesterol 3.54, small low-density lipoprotein-C 1.28, apolipoprotein B 1.34, apolipoprotein CII 45, apolipoprotein CIII 143, apolipoprotein E 52, folate >53.24;

[0074] Bone metabolism: 25-hydroxyvitamin D17.

[0075] 2023-10-16 Electroencephalogram: No obvious abnormalities were found.

[0076] TCD: basilar artery insufficiency and bilateral ophthalmic artery insufficiency.

[0077] On October 17, 2023, blood vessels in the lower limbs and neck (cardiac ultrasound) showed: 1. Localized thickening of the intima-media at the origin of the right internal carotid artery; 2. Plaque formation in the left common femoral artery; 3. Multiple small plaques in the bilateral superficial femoral artery, deep femoral artery, popliteal artery, and dorsalis pedis artery. Molecular biological test report: APOE E3 / E3 positive (+);

[0078] On March 22, 2024, the radiological diagnosis report from the Shanghai Putuo District People's Hospital and the Putuo People's Hospital affiliated to Tongji University showed: cervical vertebrae degeneration;

[0079] The color ultrasound examination report of our hospital on March 7, 2025 showed: Heart: There were no abnormalities in the heart morphology, structure and valve activity, mild mitral and aortic valve regurgitation, and decreased ventricular compliance. Thyroid: Multiple solid nodules in both lobes of the left gonad (considered TI-RADS 3), and the echo of both thyroid glands was slightly uneven. Carotid artery: The intima-media of both carotid arteries was rough and locally thickened. Liver, gallbladder, spleen and pancreas: Fatty liver, the right lobe was 133mm long and 115mm thick, the left was 87mm long and 66mm thick, and there were no obvious abnormalities in the gallbladder, spleen and pancreas. Blood vessels of both lower limbs: 1. There was no obvious dilation of the subcutaneous veins of the bilateral calves. 2. The venous blood flow signals of both lower limbs were unobstructed, and no obvious thrombosis was observed. 3. There was no obvious dilation of the bilateral great saphenous veins, and no obvious reflux signals were observed.

[0080] On March 7, 2025, our hospital's test report showed: glucose determination (dry chemical method simple blood glucose meter) 7.1mmol / L, epithelial cells (microscopic examination) +, vitamin C1+, epithelial cells + / HP, hydrogen peroxide +;

[0081] The test report of Zhenxin Community in Jiading District on April 9, 2025 showed: uric acid 444.7, estimated glomerular filtration rate 77, cholesterol 5.961, triglycerides 3.31, high-density lipoprotein 1.23, and low-density lipoprotein 3.5.

[0082] TCM diagnosis: 1. Chest pain and heartache (optional word: chest pain); 2. Accumulation-related diseases (optional words: masses; accumulation; ostentation).

[0083] Western medicine diagnosis: 1. Palpitations; 2. Fatty acid metabolism disorder; 3. Hyperuricemia;

[0084] TCM symptoms: stasis in the heart meridian syndrome, damp-heat syndrome in the qi;

[0085] TCM treatment: dissipating blood stasis, unblocking meridians and warming the heart meridians;

[0086] Treatment plan: Xiebai 15g, Shichangta 20g, Dandelion 9g, Huanglian tablets 5g, processed Pinellia 12g,

[0087] Tangerine peel 15g, raw red yeast rice 12g, Gynostemma pentaphyllum 12g, Polygonum cuspidatum 9g, Salvia miltiorrhiza 30g, Smilax glabra 50g, clean hawthorn 30g, licorice slices 9g, golden buckwheat 12g, processed Polygonatum 20g, centipede 3g, salt Eucommia ulmoides 20g, Atractylodes lancea 30g, shelled Amomum villosum 9g, then add fresh ginger 9g, Epimedium 12g, and raw Pollen Typhae 12g;

[0088] It is prepared by the preparation method: add 800ML of water to the above medicine, soak for 60 minutes, decoct for 30 minutes, and obtain 150ML of medicinal juice; add 600ML of water for the second decoction, decoct for 30 minutes, and obtain 150ML of medicinal juice.

[0089] Mix the two juices and take them twice a day, morning and evening.

[0090] Re-inspection on May 20, 2025:

[0091] Alkaline phosphatase 75.1U / L, high-density lipoprotein 1.20mmol / L, creatinine 71.44umol / L, low-density lipoprotein 2.94mmol / L, uric acid 434.3umol / L, urea nitrogen 4.37mmol / L, estimated glomerular filtration rate MDRD75ml / min, cholesterol 5.32mmol / L, triglycerides 2.58mmol / L.

[0092] After treatment, the overall therapeutic effect of patient Qian Moumou showed a partial improvement trend, lipid metabolism disorders were alleviated, total cholesterol decreased, low-density lipoprotein and triglycerides showed a downward trend, creatinine and urea nitrogen were stable, indicating that the kidney excretion function was still good. In terms of TCM symptoms, the syndrome of blood stasis in the heart meridian (chest pain and heart pain) was alleviated. Overall, the current treatment has a controlling effect on blood lipids and uric acid.

[0093] Patient name: Chen Moumou, male, 23 years old;

[0094] Physical examination: medium build, clear consciousness, good spirits, yellow complexion, steady breathing, coarse breath sounds in both lungs, heart rate 80 beats / min, soft abdomen, no tenderness, no edema in both lower limbs, medium build, good spirits, white tongue, yellow fur, and wiry and slippery pulse.

[0095] Auxiliary examination: The examination report of our hospital on 2025 / 2 / 16 showed: average platelet volume 8.50f1; uric acid 563μmol / L; low-density lipoprotein 3.87mmol / L; high-density lipoprotein 1.19mmol / L; A / GI I 1.8.

[0096] Western medicine diagnosis: 1. Fatigue syndrome; 2. Fatty liver

[0097] TCM diagnosis: 1. Dampness-blocking disease; 2. Accumulation-related disease;

[0098] TCM syndrome differentiation: Phlegm-dampness blocking the middle part of the body syndrome;

[0099] TCM treatment principles: dispel dampness and resolve phlegm;

[0100] Treatment options:

[0101] Epimedium 12g, Gynostemma pentaphyllum 15g, Smilax glabra 40g, Scutellaria baicalensis 6g, Prunella vulgaris 20g, Salvia miltiorrhiza 20g, Fraxinus 15g, Bupleurum 9g, White Poria 9g, Red Yeast Rice 15g, Daidaihua 12g, Hawthorn 30g, Corn Silk 15g, Processed Polygonum multiflorum 20g, Processed Polygonatum 20g, Cassia seed 9g, Polygonum cuspidatum 12g, and Alisma orientalis 15g;

[0102] The preparation method is adopted, one dose is taken per day, decocted in water, taken orally with Chinese medicine, and taken continuously for seven doses.

[0103] Re-examination on March 23, 2025, the test report showed: 1: total bilirubin 6.3μmol / L, 2: direct bilirubin 2.3umol / L, 3: triglyceride 0.18mmol / L, 4: indirect bilirubin 4μmol / L, 5: total cholesterol 4.3mmol / L, 6: uric acid 22μmo1 / L, 7: total protein 74.2g / L, 8: urea 4.1mmol / L, 9: low-density lipoprotein 2.85mmol / L, 10: albumin 47.5g / L, 11: high-density lipoprotein 1.25mmo1 / L, 12: creatinine 63μmol / L, 13: globulin 26.7g / L, 14: A / G I 1.8, 15: Alanine aminotransferase 20U / L, 16: Aspartate aminotransferase 17U / L, 17: γ-glutamyl transferase 33U / L, 18: Alkaline phosphatase 47U / L, 19: Total bile acid 3.8μmo1 / L, 20: Adenosine deaminase 10U / L, 21: Cholinesterase 10890U / L, 22: Prealbumin 330.8mg / L.

[0104] Uric acid decreased from 563 μmol / L to 22 μmol / L, low-density lipoprotein decreased from 3.87 mmol / L to 2.85 mmol / L, and high-density lipoprotein increased from 1.19 mmol / L to 1.25 mmol / L. These changes indicate that this Chinese herbal formula has achieved positive effects in regulating blood lipids and uric acid.

[0105] The above description is merely illustrative of certain exemplary embodiments of the present invention. It goes without saying that those skilled in the art will be able to modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and description are illustrative in nature and should not be construed as limiting the scope of protection of the claims.

Claims

1. A Chinese herbal compound with lipid-lowering and blood pressure-lowering effects, characterized in that: The raw materials include by weight: Main herbs: raw red yeast rice 12-30g and Gynostemma pentaphyllum 9-20g; Assistant medicines: one or more of clean hawthorn 12-30g, astragalus 15-60g, salvia miltiorrhiza 12-30g, and oriental rhizome 12-30g; Auxiliary drugs: one or more of corn silk 9-20g, selfheal 12-30g, processed polygonatum 12-30g, coix seed 20-60g, processed polygonum multiflorum 12-30g, knotweed 9-20g and cassia seed 9-20g.

2. The Chinese medicinal compound with lipid-lowering and blood pressure-lowering effects according to claim 1, characterized in that: The main herbs include 15g of red yeast rice and 15g of Gynostemma pentaphyllum; The auxiliary drugs include 20g of Hawthorn, 30g of Astragalus, 20g of Salvia miltiorrhiza and 20g of Alisma orientalis; The adjuvant drugs include corn silk 9g, selfheal 21g, processed polygonatum 20g, coix seed 40g, processed polygonum multiflorum 12g, polygonum cuspidatum 14g, and cassia seed 12g.

3. The Chinese medicinal compound with lipid-lowering and blood pressure-lowering effects according to claim 1, characterized in that: The main herbs include 12g of red yeast rice and 12g of Gynostemma pentaphyllum; The auxiliary medicines include 30g of pure hawthorn and 30g of salvia miltiorrhiza; The adjuvant drugs include 20g of processed Polygonatum sibiricum and 9g of Polygonum cuspidatum.

4. The Chinese medicinal compound with lipid-lowering and blood pressure-lowering effects according to claim 1, characterized in that: The main herbs include 15g of red yeast rice and 15g of Gynostemma pentaphyllum; The auxiliary drugs include 30g of Hawthorn, 20g of Salvia miltiorrhiza and 15g of Alisma orientalis; The adjuvant drugs include 15g of corn silk, 30g of selfheal, 20g of processed polygonatum, 20g of processed polygonatum, 12g of knotweed and 9g of cassia seed.

5. A method for preparing a Chinese medicinal compound having lipid-lowering and blood pressure-lowering effects, applicable to the Chinese medicinal compound according to any one of claims 1 to 4, characterized in that: The following steps are involved: S1. Selecting, by weight, the main drugs: raw red yeast rice and gynostemma pentaphyllum, the auxiliary drugs: one or more of clean hawthorn, astragalus, salvia miltiorrhiza, and oriental rhizome, and the adjuvant drugs: one or more of corn silk, selfheal, processed polygonatum, coix seed, processed polygonum multiflorum, knotweed, and cassia seed as the medicinal materials, and then washing the medicinal materials in sequence; S2. Place the cleaned medicinal materials in an open space to dry naturally, and then place the naturally dried medicinal materials in a dry and clean container and weigh them; S3, placing the medicinal materials prepared in proportion in a pot and mixing, then adding cold water, and then stirring by physical methods, heating to boiling over high heat after mixing, then decocting over low heat for 30-45 minutes, filtering out the medicinal residue, and obtaining the first drug filtrate; S4, adding water twice to the medicinal residue in S3, decocting and boiling for 25-35 minutes over a slow fire, and filtering out the medicinal residue to obtain a secondary medicinal filtrate; S5. Combine the first drug filtrate obtained in S3 and the second drug filtrate obtained in S4, and then let it settle to allow the drug residue to completely precipitate. Take the supernatant of the precipitated drug solution to obtain a traditional Chinese medicine compound with lipid-lowering and blood pressure-lowering effects.

6. The Chinese medicinal compound with lipid-lowering and blood pressure-lowering effects and its preparation method according to claim 5, characterized in that: In the S3, the high heat is to maintain a firepower of 100±5°C before boiling, and the low heat is to maintain a slightly boiling state of 80±5°C after boiling.