An extracorporeal membrane oxygenator with integrated oxygen production function

Abstract

The present application relates to the field of medical devices, in particular to an extracorporeal membrane oxygenator machine with integrated oxygen production function, a control system and a power supply unit are built in the membrane oxygenation host, a first electrical interface is formed on the outer side of the membrane oxygenation host, the first electrical interface is connected with the control system and the power supply unit; an oxygen production mechanism is fixed to the membrane oxygenation host, the oxygen production mechanism has a second electrical interface and an oxygen output interface, the second electrical interface is connected with the first electrical interface, and the oxygen output interface is connected with an oxygen inlet of the membrane oxygenation host. The present application integrates the oxygen production mechanism on the membrane oxygenation host, so that the ECMO device system has the function of producing oxygen by itself, the oxygen production mechanism is powered by the membrane oxygenation host, the generated oxygen is connected with the oxygen inlet of the membrane oxygenation host through the oxygen output interface, uninterrupted oxygen supply can be realized during patient transfer to maintain the oxygenation of the ECMO system, and the oxygen supply is no longer restricted by the amount of oxygen carried by the oxygen cylinder, so that the transfer time and distance can be greatly prolonged.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to an extracorporeal membrane oxygenation machine with integrated oxygen production function. Background Art

[0002] Extracorporeal Membrane Oxygenation (ECMO) is a key medical device used to support the lives of patients with severe cardiopulmonary failure. It temporarily replaces the patient's cardiopulmonary function through extracorporeal circulation and gas exchange, buying time for the treatment of the primary disease.

[0003] Traditional ECMO systems primarily consist of a main unit, a centrifugal pump head, an oxygenator (membrane lung), and tubing. They operate by drawing hypoxic venous blood from the patient's body, oxygenating it with externally supplied oxygen through the oxygenator, and then returning the oxygen-rich blood to the patient. In clinical practice, ECMO can be categorized into veno-arterial (VA-ECMO) and veno-venous (VV-ECMO), respectively, for combined cardiopulmonary support and respiratory support alone.

[0004] However, existing ECMO technology has significant limitations during patient transport. When patients need to be transported within or between hospitals, the ECMO system relies on external oxygen cylinders for oxygen supply. Oxygen cylinders have limited capacity, and especially in long-distance transport scenarios, depletion of oxygen in oxygen cylinders may lead to interruption of oxygenation function, directly threatening the patient's life safety. In addition, carrying and replacing oxygen cylinders increases the complexity and risk of transport, limiting the application of ECMO in mobile medical care. Summary of the Invention

[0005] The present invention provides an extracorporeal membrane oxygenation machine with an integrated oxygen production function, which is used to solve the defect of existing ECMO technology that an external oxygen cylinder is required during patient transfer, and to maintain the oxygenation of the ECMO system by using self-made oxygen during patient transfer.

[0006] The present invention provides an extracorporeal membrane oxygenation machine with an integrated oxygen production function, comprising a membrane oxygenation main unit and an oxygen production mechanism. The membrane oxygenation main unit is used to drive blood circulation and perform blood oxygenation. The membrane oxygenation main unit has a built-in control system and a power supply unit. The membrane oxygenation main unit is formed with a first electrical interface, which is connected to the control system and the power supply unit; the oxygen production mechanism is fixed to the membrane oxygenation main unit, and has a second electrical interface and an oxygen output interface. The second electrical interface is connected to the first electrical interface and is used to supply power to the oxygen production mechanism and transmit signals through the membrane oxygenation main unit. The oxygen output interface is connected to the oxygen inlet of the membrane oxygenation main unit.

[0007] According to the extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the oxygen production mechanism is detachably fixed to the side of the membrane oxygenation host through a connecting structure.

[0008] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the connection structure includes a support plate, a track groove and a locking mechanism. The support plate is hinged to the side of the membrane oxygenation main unit; the track groove is provided at the bottom of the oxygen production mechanism and is provided corresponding to the support plate, and is used for slidingly fitting with the support plate; the locking mechanism is used to lock the membrane oxygenation main unit and the oxygen production mechanism after the support plate slides into the track groove.

[0009] According to an extracorporeal membrane oxygenation machine with an integrated oxygen production function provided by the present invention, the locking mechanism includes a locking inlet, a locking interface and an unlocking button. The locking inlet is arranged on the side of the membrane oxygenation host, and a mechanical buckle is embedded in the locking inlet; the locking interface is arranged on the side of the oxygen production mechanism and is matched with the locking inlet, and a spring lock tongue is embedded in the locking interface, and the spring lock tongue is suitable for locking with the mechanical buckle in the locking inlet; the unlocking button is passed through the top of the oxygen production mechanism, the unlocking button is connected to the spring lock tongue in the locking interface, and is suitable for disengaging the spring lock tongue from the mechanical buckle by pressing the unlocking button.

[0010] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the first electrical interface and the locking inlet are both female connectors, embedded in the outer side of the membrane oxygenation host, and the second electrical interface and the locking interface are both male connectors, respectively hinged to the outer side of the oxygen production mechanism.

[0011] According to the present invention, an extracorporeal membrane oxygenation machine with integrated oxygen production function is provided. The oxygen production mechanism includes a housing, an oxygen production module, an oxygen buffer chamber, and a medical-grade gas filter. The housing is provided with the second electrical interface, the oxygen output interface, and the air inlet. The oxygen production module is disposed inside the housing, electrically connected to the second electrical interface, and the input end of the oxygen production module is connected to the air inlet. The oxygen buffer chamber is disposed inside the housing, connected to the output end of the oxygen production module, and has a built-in pressure regulating membrane in the oxygen buffer chamber for maintaining the pressure of the output oxygen. The medical-grade gas filter is disposed at the oxygen output interface, and the medical-grade gas filter is connected to the oxygen buffer chamber outlet.

[0012] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the membrane oxygenation host includes a main device and a consumable component. The main device has the built-in control system and the power supply unit. A pull-out mounting plate and a pump head drive seat are movably provided on one side of the main device. The top of the main device is rotatably connected to a protective frame. The first electrical interface is provided on the other side of the main device; the consumable component is detachably mounted on the pull-out mounting plate, the consumable component is provided with a pump head connected to the pump head drive seat, the protective frame is suitable for forming external protection for the consumable component, and an oxygen inlet is provided on the consumable component, which is connected to the oxygen output interface.

[0013] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, one end of the protective frame is rotatably connected to the top of the main device via a rotating shaft, and the protective frame is suitable for rotating along the rotating shaft to form a protective state or a retracted state. In the protective state, the protective frame forms external protection for the consumable component; in the retracted state, the protective frame is attached to the main device.

[0014] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the consumable component is a box-shaped structure, including a box body, a membrane lung, a blood inlet, a blood outlet, a water inlet, a water outlet and an exhaust window, the pump head is provided on the side of the box body facing the main device, and the oxygen inlet is provided on the other side of the box body; the membrane lung is provided in the box body, the membrane lung is connected to the oxygen inlet, and is used to provide oxygenated gas to the membrane lung through the oxygen inlet; the blood inlet and the blood outlet are provided on the side of the box body facing away from the main device, and the blood inlet and the blood outlet are respectively connected to the membrane lung; the water inlet and the water outlet are provided on the side of the box body facing away from the main device, and the water inlet and the water outlet are connected to each other through a connecting pipeline, and the connecting pipeline is arranged around the membrane lung to form a temperature regulating mechanism; the exhaust window is provided on the side of the box body, and the exhaust window is connected to the membrane lung through an exhaust valve, and is used to discharge residual gas in the membrane lung.

[0015] According to an extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention, the main device is provided with a battery compartment, and the battery compartment has at least two batteries built in; the main device is provided with a power connector on the side facing the consumable component, and the power connector and the at least two batteries in the battery compartment constitute a multi-redundant power supply structure for powering the extracorporeal membrane oxygenation machine through the power supply unit.

[0016] The extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention integrates an oxygen production mechanism on the membrane oxygenation host, so that the ECMO equipment system has the function of producing its own oxygen. The oxygen production mechanism is powered by the membrane oxygenation host, and the generated oxygen is connected to the oxygen inlet of the membrane oxygenation host through the oxygen output interface. This can achieve uninterrupted oxygen supply to maintain the oxygenation of the ECMO system during the patient transfer process, and is no longer restricted by the amount of oxygen carried in the oxygen cylinder, which can greatly extend the time and distance of transfer. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the present invention or the prior art, a brief introduction is given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0018] Figure 1 It is a structural schematic diagram of the extracorporeal membrane oxygenation machine with integrated oxygen production function provided by the present invention.

[0019] Figure 2 It is a schematic diagram of the assembly structure of the membrane lung oxygenation host and oxygen production mechanism provided by the present invention.

[0020] Figure 3 It is a schematic structural diagram of the membrane lung oxygenation host provided by the present invention.

[0021] Figure 4 This is one of the structural diagrams of the oxygen production mechanism provided by the present invention.

[0022] Figure 5 This is the second structural diagram of the oxygen production mechanism provided by the present invention.

[0023] Figure 6 It is a schematic diagram of the working principle of the oxygen production mechanism provided by the present invention.

[0024] Figure 7 This is one of the structural diagrams of the main device provided by the present invention.

[0025] Figure 8 This is the second structural diagram of the main device provided by the present invention.

[0026] Figure 9 This is one of the schematic diagrams of the consumable component structure provided by the present invention.

[0027] Figure 10 This is the second schematic diagram of the consumable component structure provided by the present invention.

[0028] Reference numerals:

[0029] 1. Membrane oxygenator main unit; 11. First electrical interface; 12. Main device; 121. Pull-out mounting plate; 122. Pump head drive seat; 123. Protective frame; 124. Battery compartment; 125. Power connector; 13. Consumable components; 131. Pump head; 132. Oxygen inlet; 133. Box body; 134. Membrane oxygenator; 135. Blood inlet; 136. Blood outlet; 137. Water inlet; 138. Water outlet; 139. Exhaust window;

[0030] 2. Oxygen generator; 21. Second electrical interface; 22. Oxygen output interface; 23. Housing; 24. Air inlet; 25. Oxygen generator module; 26. Oxygen buffer chamber; 27. Medical-grade gas filter;

[0031] 31. Support plate; 32. Track groove; 331. Locking inlet; 332. Locking interface; 333. Unlocking button. DETAILED DESCRIPTION

[0032] To make the objectives, technical solutions, and advantages of the present invention more clear, the technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.

[0033] The following combination Figures 1 to 10 The specific structure and working process of the extracorporeal membrane oxygenation machine with integrated oxygen production function of the present invention are described.

[0034] One embodiment of the present invention provides an extracorporeal membrane oxygenation machine with integrated oxygen production function, Figure 1 and Figure 2 As shown, an extracorporeal membrane oxygenation machine with integrated oxygen production function includes a membrane oxygenation host 1 and an oxygen production mechanism 2. The membrane oxygenation host 1 is used to drive blood circulation and perform blood oxygenation. The membrane oxygenation host 1 has a built-in control system and a power supply unit. A first electrical interface 11 is formed on the outer side of the membrane oxygenation host 1, and the first electrical interface 11 is connected to the control system and the power supply unit; the oxygen production mechanism 2 is fixed to the membrane oxygenation host 1, and the oxygen production mechanism 2 has a second electrical interface 21 and an oxygen output interface 22. The second electrical interface 21 is connected to the first electrical interface 11 and is used to supply power and transmit signals to the oxygen production mechanism 2 through the membrane oxygenation host 1. The oxygen output interface 22 is connected to the oxygen inlet of the membrane oxygenation host 1.

[0035] It can be understood that the extracorporeal membrane oxygenation machine with integrated oxygen production function of this embodiment, by integrating the oxygen production mechanism 2 on the membrane oxygenation host 1, enables the ECMO equipment system to have the function of self-production of oxygen. The oxygen production mechanism 2 is powered by the membrane oxygenation host 1, and the generated oxygen is connected to the oxygen inlet of the membrane oxygenation host 1 through the oxygen output interface 22. It can achieve uninterrupted oxygen supply during the patient transfer process to maintain the oxygenation of the ECMO system, no longer restricted by the amount of oxygen carried in the oxygen cylinder, and can greatly extend the time and distance of transfer.

[0036] In some embodiments of the extracorporeal membrane oxygenation machine with integrated oxygen production function of the present invention, see Figure 2 As shown, the oxygen-generating mechanism 2 is detachably fixed to the side of the membrane oxygenation host 1 through a connecting structure, so that the oxygen-generating mechanism 2 and the membrane oxygenation host 1 can be quickly installed and used.

[0037] In some specific examples, combined with Figure 3 、 Figure 4 and Figure 5 As shown, the connection structure includes a support plate 31, a track groove 32 and a locking mechanism. The support plate 31 is hinged to the side of the membrane oxygenation main unit 1; the track groove 32 is provided at the bottom of the oxygen production mechanism 2 and is corresponding to the support plate 31, and is used for slidingly fitting with the support plate 31; the locking mechanism is used to lock the membrane oxygenation main unit 1 and the oxygen production mechanism 2 after the support plate 31 slides into the track groove 32.

[0038] It can be understood that the connection structure is the core component that realizes the rapid disassembly and assembly of the oxygen production mechanism 2 and the membrane oxygenation host 1, and mainly includes a support plate 31, a track groove 32 and a locking mechanism. Among them, the support plate 31 is hinged to the side of the membrane oxygenation host 1 and can be folded and stored to reduce space occupation; the track groove 32 is set at the bottom of the oxygen production mechanism 2 and slides with the support plate 31 to provide installation guidance; the locking mechanism automatically locks after the oxygen production mechanism 2 slides into place to ensure that it does not loosen during transportation. Specifically, first rotate the support plate 31 on the side of the membrane oxygenation host 1 from the folded state to the horizontal position (such as Figure 3 As shown in the figure, align the track groove 32 at the bottom of the oxygen generator 2 with the support plate 31, and push the oxygen generator 2 along the support plate 31 until the locking mechanism is triggered and automatically locked (accompanied by a "click" sound). At this time, the second electrical interface 21 of the oxygen generator 2 and the first electrical interface 11 on the outer side of the membrane oxygenation host 1 are also docked and connected. Connect the oxygen output interface 22 of the oxygen generator 2 to the oxygen inlet of the membrane oxygenation host 1 through the trachea, completing the installation of the oxygen generator 2 and the membrane oxygenation host 1.

[0039] Furthermore, the locking mechanism includes a locking inlet 331, a locking interface 332 and an unlocking button 333. The locking inlet 331 is arranged on the side of the membrane oxygenation host 1, and a mechanical buckle is embedded in the locking inlet 331; the locking interface 332 is arranged on the side of the oxygen production mechanism 2 and is matched with the locking inlet 331. The locking interface 332 has a built-in spring lock tongue, which is suitable for locking with the mechanical buckle in the locking inlet 331; the unlocking button 333 is passed through the top of the oxygen production mechanism 2, and the unlocking button 333 is connected to the spring lock tongue in the locking interface 332, and is suitable for disengaging the spring lock tongue from the mechanical buckle by pressing the unlocking button 333.

[0040] As can be understood, as the oxygen generator 2 is pushed along the support plate 31, the locking interface 332 on the side of the oxygen generator 2 moves toward the locking inlet 331 on the side of the membrane oxygenation main unit 1. When the locking interface 332 enters the locking inlet 331, the spring lock tongue in the locking interface 332 contacts the mechanical buckle in the locking inlet 331. As the locking interface 332 moves deeper, the spring lock tongue in the locking interface 332 is decompressed and passes over the mechanical buckle in the locking inlet 331. The spring then resets, locking the spring lock tongue with the mechanical buckle. To unlock, the unlock button 333 is pressed. The unlock button 333 contacts the spring lock tongue in the locking interface 332, pulling the oxygen generator 2 outward, disengaging the spring lock tongue in the locking interface 332 from the mechanical buckle in the locking inlet 331. Continuing to pull the oxygen generator 2 outward, the locking inlet 331 and the locking interface 332 are disengaged, completing the sliding separation and disassembly of the oxygen generator 2 and the membrane oxygenation main unit 1.

[0041] In some examples, the first electrical interface 11 and the locking inlet 331 are both female connectors, embedded in the outer side of the membrane oxygenation main unit 1, while the second electrical interface 21 and the locking interface 332 are both male connectors, hingedly connected to the outer side of the oxygen generator 2. The support plate 31 on the membrane oxygenation main unit 1 and the second electrical interface 21 and the locking interface 332 on the oxygen generator 2 are all configured in a hinged and foldable state, allowing the membrane oxygenation main unit 1 and the oxygen generator 2 to operate independently without affecting their aesthetics, while also allowing them to operate in combination to form an extracorporeal membrane oxygenation system with integrated oxygen generation capabilities.

[0042] In some embodiments of the extracorporeal membrane oxygenation device with integrated oxygen generation function of the present invention, the oxygen generation mechanism 2 includes a housing 23, an oxygen generation module 25, an oxygen buffer chamber 26, and a medical-grade gas filter 27. The housing 23 is provided with a second electrical interface 21, an oxygen output interface 22, and an air inlet 24. The oxygen generation module 25 is disposed within the housing 23, electrically connected to the second electrical interface 21, and the input end of the oxygen generation module 25 is connected to the air inlet 24. The oxygen buffer chamber 26 is disposed within the housing 23, connected to the output end of the oxygen generation module 25, and has a built-in pressure regulating membrane for maintaining the pressure of the output oxygen. The medical-grade gas filter 27 is disposed at the oxygen output interface 22 and connected to the outlet of the oxygen buffer chamber 26.

[0043] As will be appreciated, this embodiment provides a specific structure for an oxygen production mechanism 2, which can achieve full process control from air separation to medical-grade oxygen supply. Specifically, the oxygen production module 25 can utilize molecular sieve pressure swing adsorption technology or membrane separation technology, increasing the oxygen concentration in the air through alternating adsorption and desorption in a two-stage adsorption tower. The oxygen buffer chamber 26 incorporates a polytetrafluoroethylene composite membrane (pressure regulating membrane) to maintain the oxygen output pressure at 80-100 kPa, with automatic overpressure relief. The medical-grade gas filter 27 can utilize a primary particulate filter (5μm filtration accuracy), a bacterial filter membrane (0.2μm filtration accuracy), and a hydrophobic, breathable layer (to prevent liquid water from entering the oxygenator), achieving a three-stage filtration process to deliver medical-grade oxygen.

[0044] Specifically, when the oxygen production mechanism 2 is working, see Figure 6 As shown, ambient air enters through the air inlet 24 (equipped with a dustproof net), enters the oxygen production module 25 from the input end of the oxygen production module 25 to increase the oxygen concentration in the air, and the oxygen-rich gas enters the oxygen buffer chamber 26. The pressure regulating membrane of the buffer chamber dynamically balances the airflow pulsation. After being filtered by the medical-grade gas filter 27, the gas is output from the oxygen output interface 22. The output oxygen-rich gas enters the oxygenator of the membrane lung oxygenation host 1 through the trachea for blood oxygenation.

[0045] In some embodiments of the extracorporeal membrane oxygenation machine with integrated oxygen production function of the present invention, see again Figure 3As shown, the membrane oxygenation host 1 includes a main device 12 and a consumable component 13. The main device 12 has a built-in control system and a power supply unit. A pull-out mounting plate 121 and a pump head drive seat 122 are movably provided on one side of the main device 12. The top of the main device 12 is rotatably connected to a protective frame 123. A first electrical interface 11 is provided on the other side of the main device 12; the consumable component 13 is detachably mounted on the pull-out mounting plate 121. The consumable component 13 is provided with a pump head 131 connected to the pump head drive seat 122. The protective frame 123 is suitable for forming external protection for the consumable component 13. An oxygen inlet 132 is provided on the consumable component 13, and the oxygen inlet 132 is connected to the oxygen output interface 22.

[0046] It can be understood that the structural design of the extracorporeal membrane oxygenation machine with integrated oxygen production function of this embodiment has mechanical protection designed for the extracorporeal membrane oxygenation machine, which is more suitable for long-distance patient transfer between hospitals. The membrane oxygenation host 1 mainly includes a reusable main device 12 and a consumable component 13 as a disposable consumable. By integrating the oxygenator and the pump head 131 on the consumable component 13, and then installing it on the pull-out mounting plate 121 of the main device 12 through a snap-fit ​​fit, a mechanical protection frame is formed for the consumable component 13 based on the protective frame 123 on the main device 12, so that the consumable component 13 is not easily mechanically impacted during the transfer process, thereby improving the safety during transfer. The extracorporeal membrane oxygenation machine with integrated oxygen production function of this embodiment is small in size, light in weight, easy to operate, and very convenient to transport. It is suitable for forming a portable, integrated, mechanically protected extracorporeal membrane oxygenation device for long-distance transfer between hospitals.

[0047] Combine Figure 7 and Figure 8 As shown, one end of the protective frame 123 is rotatably connected to the top of the main device 12 via a rotating shaft. The protective frame 123 is suitable for rotating along the rotating shaft to form a protective state or a retracted state. In the protective state, the protective frame 123 forms external protection for the consumable component 13; in the retracted state, the protective frame 123 is attached to the main device 12.

[0048] It is understood that the protective frame 123 of this embodiment is hinged to the top of the main device 12 via a rotating shaft and can rotate more than 180 degrees along the rotating shaft to switch between a protective state (expanded) and a retracted state (folded). In the protective state, the protective frame 123 is unfolded to cover the top and outside of the consumable assembly 13, forming a three-dimensional protective frame. Laboratory tests have shown that in the protective state, it can withstand a 50N lateral impact force (simulating a transport collision), reducing the consumable breakage rate by 95%. The frame structure of the protective frame 123 disperses the force, preventing localized extrusion that could cause failure of the consumable assembly 13. In the retracted state, the protective frame 123 folds and clings to the top of the main device 12, reducing the overall volume (the length is reduced from 470mm to 350mm). In the retracted state, the protective frame 123 is flush with the main device 12, making it easy to fit into a standard ambulance equipment cabinet (sized to fit a 350mm length).

[0049] Specifically, in some examples, the protective frame 123 includes two rotating parts, two lateral protection parts and side protection parts. The two rotating parts are located on both sides of the main device 12 and are respectively connected to the top sides of the main device 12 through rotating shafts; the two lateral protection parts are respectively connected to the two rotating parts. In the protective state, the two lateral protection parts are located on both sides of the top of the consumable assembly 13 to form top protection for the consumable assembly 13. In the retracted state, the two lateral protection parts are attached to the side of the main device 12; the side protection part is connected to the two lateral protection parts. In the protective state, the side protection part is located on the side of the consumable assembly 13 away from the main device 12 to form side protection for the consumable assembly 13. In the retracted state, the side protection part is attached to the top of the main device 12.

[0050] It is understandable that the two rotating parts are symmetrically distributed on both sides of the top of the main device 12, and are hinged to the device body through a rotating shaft. The rotating part serves as the rotation fulcrum of the protective frame 123, bearing the force of the lateral protective part and the side protective part. The rotating shaft can have a built-in damping bearing to ensure that a certain force (about 5N·m torque) is applied during rotation to avoid accidental shaking. The lateral protective part on each side is rigidly connected to the rotating part (such as welding or bolting). When the protective frame 123 is horizontally unfolded, the lateral protective parts on both sides cover the top of the consumable component 13 on both sides, forming an "eaves-style" protection. When the protective frame 123 is retracted, the lateral protective parts on both sides fold vertically and fit against the side of the main device 12, and can be temporarily fixed by magnetic sheets. The two ends of the side protection part are linked to the lateral protection parts on both sides through hinges or flexible connecting belts. When the protection frame 123 is in the protection state, the side protection part hangs down vertically to block the side of the consumable component 13 away from the main device 12 (the most vulnerable surface). When the protection frame 123 is retracted, the side protection part is folded and laid flat on the top of the main device 12, forming a compact storage with the lateral protection part.

[0051] Furthermore, a locking button is provided on one side of the protective frame 123. This button is suitable for locking the rotating shaft, thereby securing the protective frame 123 in either the protective or retracted position. It is understood that the protective frame 123 may have a certain degree of mechanical damping. The locking button can be configured as a spring pin structure, employing a spring pin + positioning hole design. This secures the position of the protective frame 123 in both the protective and retracted positions, preventing accidental rotation during transport. In the protective position, the spring pin inserts into the first positioning hole (110° position) on the side of the rotating shaft. In the retracted position, the spring pin inserts into the second positioning hole (0° position). The locking button can also be linked to the mechanical damping of the protective frame 123. The locking button is linked to the damper inside the rotating shaft via a connecting rod. Pressing the locking button simultaneously releases the damping pressure (reducing the operating force from 5 N·m to 1 N·m). In this embodiment, the locking button locks and unlocks the rotating shaft, thereby locking and releasing the rotation of the protective frame 123.

[0052] Specifically, the process of unfolding the protective frame 123 from the retracted state to the protective state includes the process of unlocking, rotating and locking. Among them, unlocking: pressing the locking button (spring pin structure) on the side of the protective frame 123 to release the shaft constraint. Rotation: holding the side protection part and pulling it outward, driving the rotating part to rotate about 110°, the lateral protection part changes from a vertical position to a horizontal position, and the side protection part naturally droops to a vertical state due to gravity. Locking: When the rotation reaches the end point, the locking button automatically pops into the positioning hole to fix the position of the protective frame. The process of folding the protective frame 123 from the protective state to the retracted state includes the process of unlocking and folding. Among them, unlocking: pressing the locking button again to release the shaft constraint again. Folding: pushing the side protection part upward to drive the lateral protection part to rotate and reset, the lateral protection part adheres to the side of the main device 12 (magnetically fixed), and the side protection part is flat on the top of the device.

[0053] In some embodiments, the pull-out mounting plate 121 is movably connected to the bottom of one side of the main device 12, and the pull-out mounting plate 121 forms three locking positions, including a first locking position, a second locking position and a third locking position. When the pull-out mounting plate 121 is in the first locking position, the pull-out mounting plate 121 is retracted in the main device 12; when the pull-out mounting plate 121 is in the second locking position, the pull-out mounting plate 121 is completely pulled out of the main device 12 for installing the consumable assembly 13; when the pull-out mounting plate 121 is in the third locking position, the pump head 131 of the consumable assembly 13 installed on the pull-out mounting plate 121 forms a fitting connection with the pump head drive seat 122 of the main device 12.

[0054] It can be understood that a double-track stainless steel guide rail can be used between the pull-out mounting plate 121 and the main device 12. By setting a movable warehouse inside the bottom of the main device 12, guide rails are set on both sides of the movable warehouse, and three groups of grooves are symmetrically arranged on the two guide rails. The first group of grooves corresponds to the first locking position, the second group of grooves corresponds to the second locking position, and the third group of grooves corresponds to the third locking position. A spring steel ball is set at the innermost end of the pull-out mounting plate 121, and the three locking positions of the pull-out mounting plate 121 are converted by the spring steel ball being clamped into different groove positions on the guide rail. Among them, when the pull-out mounting plate 121 is in the first locking position, the pull-out mounting plate 121 is fully retracted, the spring steel ball is stuck in the first group of grooves, and the outer end of the pull-out mounting plate 121 is flush with the main device 12; when the pull-out mounting plate 121 is in the second locking position, it is the installation position of the consumable component 13, the spring steel ball is stuck in the second group of grooves, exposing the entire pull-out mounting plate 121, and the consumable component 13 can be installed on the pull-out mounting plate 121; when the pull-out mounting plate 121 is in the third locking position, it is the working connection position, the spring steel ball is stuck in the third group of grooves, and at this time the pump head 131 of the consumable component 13 is magnetically coupled with the pump head drive seat 122 of the main device 12.

[0055] When not in use, the pull-out mounting plate 121 is in the first locking position, and the pull-out mounting plate 121 is completely stored in the main device 12. When the consumable component 13 needs to be installed, the pull-out mounting plate 121 of the main device 12 is completely pulled out, and the pull-out mounting plate 121 moves from the first locking position to the second locking position. At this time, the consumable component 13 can be installed in the mounting socket on the pull-out mounting plate 121, and then, the pull-out mounting plate 121 is pushed to the second locking position. At this time, the pump head 131 of the consumable component 13 will fit tightly in the pump head drive seat 122 of the main device 12. Finally, the protective frame 123 is rotated and locked to form a mechanical frame protection for the consumable component 13.

[0056] In some embodiments of the extracorporeal membrane oxygenation device with integrated oxygen production function of the present invention, the consumable component 13 is a box-shaped structure. Figure 9 and Figure 10As shown, the consumable component 13 includes a box body 133, a membrane lung 134, a blood inlet 135, a blood outlet 136, a water inlet 137, a water outlet 138, an exhaust window 139 and a membrane lung observation window. A pump head 131 is provided on the side of the box body 133 facing the main device 12, and an oxygen inlet 132 is provided on the other side of the box body 133; the membrane lung 134 is provided in the box body 133, and the membrane lung 134 is connected to the oxygen inlet 132 for providing oxygenated gas to the membrane lung 134 through the oxygen inlet 132; the blood inlet 135 and the blood outlet 138 are connected to the blood inlet 139. 36 is arranged on the side of the box body 133 facing away from the main device 12, and the blood inlet 135 and the blood outlet 136 are respectively connected to the membrane lung 134; the water inlet 137 and the water outlet 138 are arranged on the side of the box body 133 facing away from the main device 12, and the water inlet 137 and the water outlet 138 are connected through a connecting pipeline, and the connecting pipeline is arranged around the membrane lung 134 to form a temperature regulating mechanism; the exhaust window 139 is arranged on the side of the box body 133, and the exhaust window 139 is connected to the membrane lung 134 through an exhaust valve, which is used to discharge residual gas in the membrane lung 134.

[0057] It can be understood that the consumable component 13 integrates the pump head 131 and the membrane lung 134 as well as the connecting pipes therebetween to form a box-shaped consumable structure. The pump head 131 is connected to the pump head drive base 122 of the main device 12 through magnetic coupling (non-contact drive), reducing mechanical wear and contamination risks. The pump head 131 integrates an impeller or centrifugal pump structure to drive blood flow; the oxygen inlet 132 is connected to a medical oxygen source to provide oxygenated gas to the membrane lung 134 (which may be equipped with a gas flow control valve); the blood inlet 135 and the blood outlet 136 use quick connectors (such as Luer lock or snap-on type), which support one-handed plugging and unplugging and can be quickly disconnected in an emergency. Among them, the blood inlet 135 is used to connect to the patient's vein (drainage of blood), and the blood outlet 136 is connected to the artery (re-infusion of oxygenated blood); the water inlet 137 and the water outlet 138 are used to connect to a water tank or temperature control equipment to regulate the temperature of the membrane lung (to prevent blood condensation or overheating); the exhaust window 139 is used to discharge residual gas in the membrane lung 134 to avoid the risk of gas embolism; the membrane lung observation window is set as a transparent area, which can directly observe the blood color and bubbles in the oxygenator (membrane lung 134) to assist in judging the oxygenation efficiency. The blood inlet 135, blood outlet 136, water inlet 137, and water outlet 138 all feature quick-connect connectors, facilitating insertion and removal of external arteriovenous tubing. The membrane lung observation window is transparent, allowing medical staff to observe the inside during pre-filling and use. Alternatively, the entire consumable assembly 13 can be designed with a transparent housing 133 to facilitate observation of the entire interior.

[0058] In some specific examples, the box body 133 uses a medical-grade polycarbonate (PC) transparent shell with a thickness of 2.5mm, which has both impact resistance and visualization requirements; the pump head 131 is integrated on the front side of the box body 133, and a 3mm alignment tolerance is reserved for the magnetic coupling area with the pump head drive seat 122 of the main device 12; the membrane lung 134 adopts a hollow fiber membrane structure with an effective oxygenation area of ​​1.8m 2 , fixed to the bracket inside the box body 133 by laser welding; the oxygen inlet 132 is located in the middle of the right side of the box body 133, adopts a screw-type anti-drop interface, and has a built-in 0.2μm bacterial filter to avoid gas contamination; the blood inlet 135 is located at the upper back side of the box body 133, adopts a quick connector with Luer lock, tilted 15° for easy plugging and unplugging, reducing pipeline distortion and the risk of hemolysis; the blood outlet 136 is located at the lower back side of the box body 133, and is integrated with a pressure sensing groove (for docking with the sensor aviation connector) to monitor the return pressure in real time; The water inlet 137 and the water outlet 138 are located in the middle of the rear side of the box body 133 and are color-coded (blue for water inlet / red for water outlet); the exhaust window 139 is symmetrically arranged on both sides of the box body 133, and adopts a hydrophobic exhaust membrane (pore size 0.45μm) + manual exhaust valve dual channel, which automatically exhausts and prevents liquid leakage; the membrane lung observation window is also symmetrically arranged on both sides of the box body 133 to accurately judge the blood filling volume and bubbles; at the same time, a groove or a protruding structure can be set on the box body 133 to form a hand buckle, which is convenient for grasping the consumable component 13 for installation / disassembly.

[0059] Furthermore, a mounting base is formed on the drawer mounting plate 121, and a fastening piece is provided at the bottom of the box body 133, through which the consumable assembly 13 is fastened and connected to the mounting base. The fastening piece at the bottom of the box body 133 and the mounting base on the drawer mounting plate 121 form a quick-plug interface structure, and protrusions can be symmetrically provided at both ends of the fastening piece, and the inner ends of the protrusions are connected to springs. The protrusions are clamped into the mounting base on the drawer mounting plate 121 to form the consumable assembly 13 on the drawer mounting plate 121. At the same time, an unlocking button is provided on the side of the box body 133. The unlocking button is provided through the box body 133 and abuts against the protrusion. By pressing the unlocking button, the protrusion compresses the spring and contracts, thereby separating the consumable assembly 13 from the drawer mounting plate 121.

[0060] In some embodiments of the extracorporeal membrane oxygenation (ECMO) system with integrated oxygen generation, the main device 12 includes a built-in control system and power supply unit. These control systems and power supply units are similar to those of conventional ECMO devices and are not described in detail here. In this embodiment, a human-machine interface panel and adjustment knob are located on the side of the main device 12 facing away from the consumable assembly 13 (the front of the main device 12). These panels and knobs are electrically connected to the control system. A brim structure is formed on the edge of the main device 12 facing away from the consumable assembly 13, surrounding the panel and knob.

[0061] It is understandable that the front of the device is mainly composed of a human-machine interaction panel, adjustment knobs, indicator lights, etc. The human-machine interaction panel mainly displays the two most important parameters: pump head speed and blood flow, as well as some prompts and alarm information. An adjustment knob is set on one side of the human-machine interaction panel, which can be used to adjust the speed and flow. Next is the operation bar with buttons and indicator lights. On the side of the operation bar is a USB port with a protective cover. The front of the main device 12 has a brim design, which can block a certain amount of light to ensure the clear display of the human-machine interaction panel screen, and can also provide mechanical protection for the adjustment knob to prevent accidental collision; there is a honeycomb horn on the right side of the main device 12, which can be used to issue an alarm prompt sound; there is a honeycomb heat dissipation vent on the side of the main device 12, which can play a role in ventilation and heat dissipation. The honeycomb porous structure can effectively improve the electromagnetic compatibility (EMC) protection capability of the device.

[0062] Furthermore, in some examples, a display light strip is provided on one side of the human-machine interface panel. This display light strip is electrically connected to the control system and independently displays the pump speed and blood flow rate. For particularly important speed and flow rate information, this example considers two heterogeneous redundancy methods: digital display on the human-machine interface panel screen and indication by a display light strip. To prevent extreme situations such as damage to the human-machine interface panel, the speed and flow rate information is displayed on the side of the main device 12 in the form of a display light strip, providing heterogeneous redundancy and reliability.

[0063] A battery compartment 124 is located at the lower front of the main device 12, housing at least two batteries. A power connector 125 is located on the side of the main device 12 facing the consumables assembly 13. This connector and the at least two batteries within the battery compartment 124 form a multi-redundant power supply structure. The power connector 125 allows for connection to an external 24V DC power supply, an external AC power supply, or an external UPS power supply. The batteries within the battery compartment 124 can also be powered by lithium batteries, creating a multi-redundant solution that alternates between external and lithium battery power. During transport, the oxygenator in the membrane oxygenation main unit 1 receives oxygen from the electrically powered oxygen generator 2. Therefore, transport operation time is primarily affected by the power supply. Relatively speaking, whether using external AC power, internal lithium batteries, or an external UPS power supply, obtaining electricity is far easier than obtaining oxygen, thus significantly extending transport time and distance.

[0064] Furthermore, the side of the main device 12 facing the consumable assembly 13 (the rear of the main device 12) is equipped with a sensor aviation connector and a network communication interface. The sensor aviation connector connects to the flow sensor and bubble detection sensor built into the consumable assembly 13 to obtain blood flow and bubble count information within the consumable assembly 13; the network communication interface is used to transmit and exchange data with external devices. The power connector 125, the sensor aviation connector, and the network communication interface utilize separate connectors. It is understood that the rear of the main device 12 has three connectors: the power connector 125, the aviation plug interface for the flow / bubble sensor, and the network or data bus communication interface. These three connectors utilize different sizes or connector types, providing a foolproof design to prevent medical personnel from accidentally plugging or unplugging during emergency treatment.

[0065] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the present invention.

Claims

1. An extracorporeal membrane oxygenation machine with integrated oxygen production function, characterized in that: include: A membrane oxygenation host (1) is used to drive blood circulation and perform blood oxygenation, wherein the membrane oxygenation host (1) has a built-in control system and a power supply unit, and the membrane oxygenation host (1) is formed with a first electrical interface (11), wherein the first electrical interface (11) is connected to the control system and the power supply unit; An oxygen production mechanism (2), the oxygen production mechanism (2) being detachably fixed to a side surface of the membrane oxygenation host (1) via a connecting structure, the oxygen production mechanism (2) having a second electrical interface (21) and an oxygen output interface (22), the second electrical interface (21) being connected to the first electrical interface (11) and being used for supplying power and transmitting signals to the oxygen production mechanism (2) via the membrane oxygenation host (1), and the oxygen output interface (22) being connected to the oxygen inlet of the membrane oxygenation host (1); The connection structure comprises a support plate (31), a track groove (32) and a locking mechanism, wherein the support plate (31) is hinged to the side of the membrane oxygenation main unit (1); the track groove (32) is arranged at the bottom of the oxygen production mechanism (2) and is arranged corresponding to the support plate (31) for slidingly fitting with the support plate (31); and the locking mechanism is used to lock the membrane oxygenation main unit (1) and the oxygen production mechanism (2) after the support plate (31) slides into the track groove (32).

2. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to claim 1, characterized in that: The locking mechanism comprises: A locking inlet (331) is provided on the side of the membrane oxygenation main unit (1), and a mechanical buckle is embedded in the locking inlet (331); A locking interface (332) is provided on a side of the oxygen production mechanism (2) and is matched with the locking inlet (331); the locking interface (332) has a built-in spring lock tongue, and the spring lock tongue is suitable for forming a lock with the mechanical buckle in the locking inlet (331); An unlocking button (333) is provided on the top of the oxygen production mechanism (2), and the unlocking button (333) is connected to the spring lock tongue in the locking interface (332), and is suitable for disengaging the spring lock tongue from the mechanical buckle by pressing the unlocking button (333).

3. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to claim 2, characterized in that: The first electrical interface (11) and the locking inlet (331) are both female connectors, embedded in the outer side of the membrane oxygenation host (1), and the second electrical interface (21) and the locking interface (332) are both male connectors, respectively hinged on the outer side of the oxygen production mechanism (2).

4. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to any one of claims 1 to 3, characterized in that: The oxygen production mechanism (2) comprises: a housing (23), wherein the second electrical interface (21), the oxygen output interface (22) and the air inlet (24) are provided on the housing (23); An oxygen production module (25) is disposed inside the housing (23), the oxygen production module (25) is electrically connected to the second electrical interface (21), and an input end of the oxygen production module (25) is connected to the air inlet (24); An oxygen buffer chamber (26) is provided inside the housing (23), the oxygen buffer chamber (26) is connected to the output end of the oxygen production module (25), and the oxygen buffer chamber (26) has a built-in pressure regulating membrane for maintaining the pressure of the output oxygen; A medical-grade gas filter (27) is provided at the oxygen output interface (22), and the medical-grade gas filter (27) is connected to the outlet of the oxygen buffer chamber (26).

5. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to any one of claims 1 to 3, characterized in that: The membrane oxygenation host (1) comprises: A main device (12), wherein the main device (12) has the control system and the power supply unit built in, a pull-out mounting plate (121) and a pump head drive seat (122) movably provided on one side of the main device (12), a protective frame (123) rotatably connected to the top of the main device (12), and the first electrical interface (11) provided on the other side of the main device (12); The consumable component (13) is detachably mounted on the pull-out mounting plate (121), the consumable component (13) is provided with a pump head (131) connected to the pump head drive seat (122), the protective frame (123) is suitable for forming external protection for the consumable component (13), and the consumable component (13) is provided with an oxygen inlet (132), and the oxygen inlet (132) is connected to the oxygen output interface (22).

6. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to claim 5, characterized in that: One end of the protective frame (123) is rotatably connected to the top of the main device (12) via a rotating shaft, and the protective frame (123) is suitable for rotating along the rotating shaft to form a protective state or a retracted state. In the protective state, the protective frame (123) forms external protection for the consumable component (13); in the retracted state, the protective frame (123) is attached to the main device (12).

7. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to claim 5, characterized in that: The consumable component (13) is a box-shaped structure, comprising: A box body (133), wherein the pump head (131) is provided on one side of the box body (133) facing the main device (12), and the oxygen inlet (132) is provided on the other side of the box body (133); A membrane lung (134) is disposed in the box body (133), and the membrane lung (134) is connected to the oxygen inlet (132) and is used to provide oxygenated gas to the membrane lung (134) through the oxygen inlet (132); A blood inlet (135) and a blood outlet (136) are provided on a side of the box body (133) facing away from the main device (12), and the blood inlet (135) and the blood outlet (136) are respectively connected to the membrane lung (134); A water inlet (137) and a water outlet (138) are provided on a side of the box body (133) facing away from the main device (12); the water inlet (137) and the water outlet (138) are connected via a connecting pipeline, and the connecting pipeline is arranged around the membrane lung (134) to form a temperature regulating mechanism; An exhaust window (139) is provided on the side of the box body (133), and the exhaust window (139) is connected to the membrane lung (134) through an exhaust valve, and is used to exhaust residual gas in the membrane lung (134).

8. The extracorporeal membrane oxygenation machine with integrated oxygen production function according to claim 5, characterized in that: The main device (12) is provided with a battery compartment (124), and the battery compartment (124) has at least two batteries built therein; the main device (12) is provided with a power connector (125) on a side facing the consumable component (13), and the power connector (125) and the at least two batteries in the battery compartment (124) constitute a multi-redundant power supply structure for supplying power to the extracorporeal membrane oxygenation machine through the power supply unit.

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