Uterine myoma composite ablation instrument for high-frequency focused ultrasound combined photodynamic therapy

Abstract

The invention provides a hysteromyoma composite ablatometer for high-frequency focused ultrasound combined with photodynamic therapy, and relates to the technical field of hysteromyoma treatment equipment.The hysteromyoma composite ablatometer comprises a host, a display module and a diagnosis and treatment bed, an adjustable cantilever is installed on one side of the diagnosis and treatment bed, and a treatment probe is arranged at the end of the adjustable cantilever; a contact end is installed at the opening position of the lower end of the treatment probe, an ultrasonic treatment control module and an optical treatment control module are arranged on the upper side of the contact end in the treatment probe, and a terminal cooling assembly used for cooling the contact end, the optical treatment control module and the ultrasonic treatment control module is installed outside the treatment probe. The ultrasonic imaging control module is arranged on the outer surface of the treatment probe, the cooling assembly can generate high-speed airflow and guide the airflow into the cooling channel, the bottom sheet and the top sheet are cooled through the airflow, temperature rise of the contact end when the contact end makes contact with the skin part of a patient is avoided, and the phenomenon that the skin is injured in the using process is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of uterine fibroid treatment equipment, and in particular to a uterine fibroid composite ablation device combining high-frequency focused ultrasound with photodynamic therapy. Background Art

[0002] Uterine fibroids are one of the most common benign tumors in the female reproductive organs and one of the most common tumors in the human body. They are also called fibroids or uterine fibroids. Because uterine fibroids are mainly formed by the proliferation of uterine smooth muscle cells, with a small amount of fibrous connective tissue as a supporting tissue, it is more accurate to call them uterine leiomyomas. There is a widespread demand for clinical treatment of uterine fibroids. Surgical resection of the fibroids is the most common treatment method, but it has disadvantages such as high trauma. Therefore, the development of minimally invasive or non-invasive treatments is crucial.

[0003] A search revealed a prior art focused ultrasound uterine fibroid treatment device with the authorized publication number CN203989522U. The device comprises a movable bed with a transverse movable axis disposed below the bed, a bottom support frame disposed below the transverse movable axis, a support chassis disposed at the lower end of the bottom support frame, a circuit tube disposed at the left end of the support chassis, a retractable support rod disposed at the left end of the circuit tube, a retractable force arm disposed on the retractable support rod, a wire outlet disposed at the bottom end of the retractable support rod, and a power supply wire disposed at the left end of the wire outlet. The device effectively treats uterine fibroids and other diseases without trauma, reducing the workload of medical staff and the pain endured by patients.

[0004] In the above technical solution, during treatment, the treatment probe needs to be attached to the patient's abdomen, and ultrasonic waves are emitted through the ultrasonic transmitting device and the focal position of the ultrasonic waves is precisely controlled to treat the tumor part of the patient's body. Since the treatment probe needs to be attached to the patient's abdomen, the treatment probe part will emit high temperature during the treatment process, which can easily cause damage to the patient's skin. For this reason, we propose a uterine fibroids composite ablation device that combines high-frequency focused ultrasound with photodynamic therapy. Summary of the Invention

[0005] In response to the shortcomings of the existing technology, the present invention provides a uterine fibroids composite ablation device that combines high-frequency focused ultrasound with photodynamic therapy, which solves the technical problem that the treatment probe needs to be attached to the patient's abdomen during treatment, and the treatment probe will emit high temperature during the treatment, which can easily cause damage to the patient's skin. Technical Solution

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: a high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroids composite ablation device, including a main unit, a display module and a treatment bed, an adjustable cantilever is installed on one side of the treatment bed, a treatment probe is provided at the end of the adjustable cantilever, a contact end is installed at the lower opening of the treatment probe, an ultrasonic treatment control module and an optical treatment control module are provided on the upper side of the contact end inside the treatment probe, a terminal cooling assembly for cooling the contact end and the optical treatment control module and the ultrasonic treatment control module is installed on the outside of the treatment probe, and an ultrasonic imaging control module is provided on the outer surface of the treatment probe.

[0007] Preferably, the contact end includes a bottom sheet and a top sheet, and the bottom sheet and the top sheet are both installed at the lower opening of the treatment probe. A cooling channel is provided on the contact surface of the bottom sheet and the top sheet, and one end of the cooling channel is connected to an exhaust port, and the exhaust port is provided on the outside of the bottom sheet and the top sheet, and the other end of the cooling channel is connected to the terminal cooling assembly.

[0008] Preferably, the terminal cooling assembly includes an air pump, which is installed on the outside of the treatment probe. The air outlet of the air pump is equipped with an air duct, which is connected to the inside of the treatment probe. The treatment probe is provided with an air outlet, and an air pipe is installed outside the air duct and is connected to the air pipe. The end of the air pipe is connected to the other end of the cooling channel.

[0009] Preferably, the adjustable cantilever includes a bracket, a rotating shaft is fixedly mounted on the lower end of the bracket, a mounting seat is rotatably connected to the lower end of the rotating shaft, and the mounting seat is fixedly mounted on the outer side of the diagnosis and treatment bed.

[0010] Preferably, a transverse slide rail is installed on the upper end of the bracket, a moving seat is fixedly installed on the movable end of the transverse slide rail, a guide sleeve is fixedly installed on the lower end of the moving seat, a slide rod is slidably installed inside the guide sleeve, one end of the slide rod is fixedly installed with a vertical guide rail, a sliding member is slidably installed inside the vertical guide rail, and one end of the sliding member is fixedly connected to the treatment probe.

[0011] Preferably, a threaded hole is provided on the sliding member, a threaded rod is threadedly connected inside the threaded hole, both ends of the threaded rod are rotatably installed inside the vertical guide rail, and the upper end of the threaded rod is rotatably extended to the outside of the vertical guide rail and is fixedly connected to a handle.

[0012] Preferably, the ultrasonic therapy control module includes an ultrasonic transmitter, a transducer, an ultrasonic power amplifier and a temperature sensor in a circular array on the upper side of the top sheet, and the ultrasonic transmitter, transducer, ultrasonic power amplifier and temperature sensor are electrically connected to a controller, and the controller is electrically connected to the host.

[0013] Preferably, the optical therapy control module includes a laser emitter arranged at the center of the ultrasound emitter array, and a spectrometer, a liquid crystal tunable filter and a temperature monitoring sensor electrically connected to the laser emitter, and the laser emitter, spectrometer, liquid crystal tunable filter and temperature monitoring sensor are electrically connected to the controller.

[0014] Preferably, the ultrasound imaging control module includes an ultrasound probe installed outside the treatment probe, and a signal generator, a signal processor and a data recorder electrically connected to the ultrasound probe, and the ultrasound probe, signal generator, signal processor and data recorder are electrically connected to the controller. Beneficial effects

[0015] The present invention provides a uterine fibroid ablation device that combines high-frequency focused ultrasound with photodynamic therapy. It has the following beneficial effects: A rotating shaft is provided to drive the bracket to rotate with the mounting base as the center, so that the use range of the treatment probe can be adjusted over a large range, which is convenient for adjustment according to the patient's lying posture and body position, thereby improving the convenience of use.

[0016] Firstly, by using the synergistic effect of high-frequency focused ultrasound and photodynamic therapy of the optical treatment control module and the ultrasound treatment control module, efficient ablation of uterine fibroids is achieved, combining the advantages of the two therapies to improve treatment effects, reduce complications, and shorten recovery time. The terminal cooling assembly can generate high-speed airflow and guide the airflow into the cooling channel, cooling the bottom sheet and the top sheet through the airflow, preventing the contact end from heating up when in contact with the patient's skin, and avoiding skin damage during use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the structure of the treatment probe of the present invention; Figure 3 This is a schematic diagram of the internal structure of the treatment probe of the present invention; Figure 4 for Figure 3 Schematic diagram of the structure enlarged at a in FIG; Figure 5 Schematic diagram of the structure of the top sheet and the bottom sheet of the present invention; Figure 6 It is a schematic structural diagram of the overall side view of the present invention; Figure 7 for Figure 6 Schematic diagram of the structure enlarged at point b; Figure 8This is a schematic structural diagram of the ultrasonic therapy control module of the present invention; Figure 9 This is a schematic diagram of the structure of the optical therapy control module of the present invention; Figure 10 It is a structural schematic diagram of the ultrasonic imaging control module of the present invention.

[0018] Among them, 1. main unit; 10. display module; 2. diagnosis and treatment bed; 3. adjustable cantilever; 31. bracket; 311. rotating shaft; 312. mounting seat; 32. horizontal slide rail; 33. movable seat; 34. guide sleeve; 35. slide rod; 36. vertical guide rail; 37. sliding part; 38. threaded hole; 39. threaded rod; 40. handle; 4. treatment probe; 5. contact end; 51. bottom sheet; 52. top sheet; 53. cooling channel; 54. exhaust port; 6. ultrasound imaging control module; 61. ultrasound probe; 7. terminal cooling assembly; 71. air pump; 72. airway; 73. trachea; 8. ultrasound treatment control module; 81. ultrasound transmitter; 9. optical treatment control module; 91. laser transmitter. DETAILED DESCRIPTION

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Embodiment 1:

[0020] like Figures 1-10 As shown, an embodiment of the present invention provides a uterine fibroids composite ablation device of high-frequency focused ultrasound combined with photodynamic therapy, comprising a main unit 1, a display module 10 and a treatment bed 2, an adjustable cantilever 3 is installed on one side of the treatment bed 2, a treatment probe 4 is provided at the end of the adjustable cantilever 3, a contact end 5 is installed at the lower opening of the treatment probe 4, an ultrasound treatment control module 8 and an optical treatment control module 9 are provided on the upper side of the contact end 5 inside the treatment probe 4, a terminal cooling assembly 7 for cooling the contact end 5 and the optical treatment control module 9 and the ultrasound treatment control module 8 is installed on the outside of the treatment probe 4, and an ultrasound imaging control module 6 is provided on the outer surface of the treatment probe 4.

[0021] like Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 as well as Figure 5As shown, in this embodiment, the contact end 5 includes a bottom sheet 51 and a top sheet 52. The bottom sheet 51 and the top sheet 52 are both installed at the lower opening of the treatment probe 4. A cooling channel 53 is provided on the contact surface of the bottom sheet 51 and the top sheet 52. One end of the cooling channel 53 is connected to an exhaust port 54. The exhaust port 54 is provided on the outside of the bottom sheet 51 and the top sheet 52. The other end of the cooling channel 53 is connected to the terminal cooling assembly 7. The terminal cooling assembly 7 can generate a high-speed airflow and guide the airflow into the cooling channel 53. The bottom sheet 51 and the top sheet 52 are cooled by the airflow to avoid the temperature of the contact end 5 from rising when it contacts the patient's skin, thereby avoiding skin damage during use.

[0022] like Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 as well as Figure 5 As shown, in this embodiment, the terminal cooling assembly 7 includes an air pump 71, which is installed on the outside of the treatment probe 4. The air outlet of the air pump 71 is installed with an air duct 72, which is connected to the inside of the treatment probe 4. The treatment probe 4 is provided with an air outlet, and the air duct 72 is installed outside and connected with an air pipe 73. The end of the air pipe 73 is connected to the other end of the cooling channel 53. During use, the air pump 71 can drive the airflow to flow into the air duct 72 at a high speed, and enter the treatment probe 4 through the air duct 72 to cool the ultrasonic treatment control module 8 and the optical treatment control module 9, so as to avoid the phenomenon that the internal temperature of the treatment probe 4 is too high and causes damage to the electrical components.

[0023] like Figure 6 and Figure 7 As shown, in this embodiment, the adjustable cantilever 3 includes a bracket 31, and the lower end of the bracket 31 is fixedly installed with a rotating shaft 311. The lower end of the rotating shaft 311 is rotatably connected to a mounting base 312, and the mounting base 312 is fixedly installed on the outside of the treatment bed 2. When in use, the rotating shaft 311 is provided to drive the bracket 31 to rotate with the mounting base 312 as the center of the circle, so that the use range of the treatment probe 4 can be adjusted over a large range, which is convenient for adjustment according to the patient's lying posture and body position, thereby improving the convenience of use.

[0024] like Figure 6 and Figure 7As shown, in this embodiment, the upper end of the bracket 31 is equipped with a transverse slide rail 32, the movable end of the transverse slide rail 32 is fixedly equipped with a movable seat 33, the lower end of the movable seat 33 is fixedly equipped with a guide sleeve 34, the inner sliding installation of a slide rod 35 is slidably installed in the guide sleeve 34, one end of the slide rod 35 is fixedly equipped with a vertical guide rail 36, and the inner sliding installation of a slide member 37 is slidably installed in the vertical guide rail 36, and one end of the slide member 37 is fixedly connected to the treatment probe 4. The transverse slide rail 32 is provided so that the movable seat 33 and the treatment probe 4 can be moved and adjusted to their use positions along the transverse slide rail 32, which is convenient for lateral fine-tuning according to the patient's tumor position during treatment, thereby improving convenience of use. The guide sleeve 34 and the slide rod 35 are provided so that the treatment probe 4 can be moved and adjusted to their use positions along the guide sleeve 34 and the slide rod 35, which is convenient for longitudinal fine-tuning according to the patient's tumor position during treatment, thereby improving convenience of use.

[0025] like Figure 6 and Figure 7 As shown, in this embodiment, a threaded hole 38 is provided through the sliding member 37, and a threaded rod 39 is threadedly connected inside the threaded hole 38. Both ends of the threaded rod 39 are rotatably installed inside the vertical guide rail 36, and the upper end of the threaded rod 39 is rotatably extended to the outside of the vertical guide rail 36 and is fixedly connected to a handle 40. During use, the sliding member 37 and the treatment probe 4 can be driven to adjust their position vertically by rotating the threaded rod 39, and the position of the treatment probe 4 can be adjusted according to the height of the patient's abdomen, so that the contact end 5 of the treatment probe 4 fits against the patient's abdomen, and the external thread of the threaded rod 39 cooperates with the internal thread of the threaded hole 38, so that the weight of the entire treatment probe 4 can be borne during use, thereby reducing the pressure and weight on the patient's abdomen.

[0026] like Figure 8 As shown, in this embodiment, the ultrasonic treatment control module 8 includes an ultrasonic transmitter 81, a transducer, an ultrasonic power amplifier and a temperature sensor in a circular array on the upper side of the top sheet 52. The ultrasonic transmitter 81, the transducer, the ultrasonic power amplifier and the temperature sensor are electrically connected to a controller, and the controller is electrically connected to the host 1. The ultrasonic transmitter 81 generates a high-frequency electrical signal and converts the electrical signal into ultrasonic energy through the transducer, and focuses the ultrasonic energy on the treatment site, causing its temperature to rise rapidly, resulting in coagulative necrosis of the tissue in the treatment site, thereby achieving a non-invasive treatment effect. The controller can control the ultrasonic power amplifier to adjust the output power of the ultrasonic transmitter 81.

[0027] like Figure 9As shown, in this embodiment, the optical therapy control module 9 includes a laser emitter 91 arranged at the center of the ultrasound emitter 81 array, and a spectrometer, a liquid crystal tunable filter and a temperature monitoring sensor electrically connected to the laser emitter 91. The laser emitter 91, the spectrometer, the liquid crystal tunable filter and the temperature monitoring sensor are electrically connected to the controller. The spectrometer and the liquid crystal tunable filter can monitor the laser wavelength of the laser emitter 91 in real time to ensure the accuracy of wavelength adjustment. The temperature monitoring sensor can monitor the working temperature of the laser emitter 91 in real time. The controller can control the laser emitter 91 to emit laser to activate the photosensitizer injected into the patient's tumor site. The photosensitizer generates reactive oxygen under the irradiation of light of a specific wavelength, which will destroy the cell membrane, mitochondria and DNA of the tumor cells, thereby killing the tumor tissue. By adopting the synergistic effect of the high-frequency focused ultrasound and photodynamic therapy of the optical therapy control module 9 and the ultrasound therapy control module 8, efficient ablation of uterine fibroids is achieved, combining the advantages of the two therapies, improving the treatment effect, reducing complications, and shortening the recovery time.

[0028] like Figure 10 As shown, in this embodiment, the ultrasound imaging control module 6 includes an ultrasound probe 61 installed on the outside of the treatment probe 4, and a signal generator, a signal processor and a data recorder electrically connected to the ultrasound probe 61. The ultrasound probe 61 contains a piezoelectric crystal for transmitting and receiving ultrasound waves. The ultrasound probe 61, the signal generator, the signal processor and the data recorder are electrically connected to the controller. The signal generator is used to generate electrical pulses, which are converted into ultrasound waves through the piezoelectric crystals in the ultrasound probe 61. The frequency, duration and amplitude of the pulses can be adjusted. The signal processor is used to receive the signal returned by the probe, amplify, filter and process it, and finally generate an ultrasound image and transmit the image to the display module 10 of the host 1 for display. It can monitor the position and size of uterine fibroids in real time to ensure the accuracy of treatment.

[0029] Working principle: When in use, the ultrasonic probe 61 emits ultrasonic waves to the patient's abdomen and receives reflected ultrasonic signals. The signal processor amplifies, filters and processes the ultrasonic signals, and finally generates an ultrasonic image and transmits the image to the display module 10 of the host 1 for display, which can monitor the location and size of uterine fibroids in real time. Adjust the adjustable cantilever 3 according to the use position to align the position of the treatment probe 4 with the tumor position; The ultrasonic transmitter 81 generates a high-frequency electrical signal and converts the electrical signal into ultrasonic energy through the transducer, and focuses the ultrasonic energy on the treatment area, causing the temperature to rise rapidly, resulting in coagulative necrosis of the tissue in the treatment area; The controller can control the laser emitter 91 to emit laser to activate the photosensitizer injected into the patient's tumor site. The photosensitizer generates reactive oxygen under the irradiation of light of a specific wavelength, which will destroy the cell membrane, mitochondria and DNA of the tumor cells, thereby killing the tumor tissue. By adopting the synergistic effect of the high-frequency focused ultrasound and photodynamic therapy of the optical treatment control module 9 and the ultrasound treatment control module 8, efficient ablation of uterine fibroids can be achieved, combining the advantages of the two therapies, improving the treatment effect, reducing complications, and shortening the recovery time.

[0030] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not limitations on the implementation methods of the present invention. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made based on the above description. It is impossible to list all the implementation methods here. Any obvious changes or modifications derived from the technical solution of the present invention are still within the scope of protection of the present invention.

Claims

1. A high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation, comprising a host (1), a display module (10) and a diagnosis and treatment bed (2), characterized in that: An adjustable cantilever (3) is installed on one side of the diagnosis and treatment bed (2), a treatment probe (4) is provided at the end of the adjustable cantilever (3), a contact end (5) is installed at the lower opening of the treatment probe (4), an ultrasound treatment control module (8) and an optical treatment control module (9) are provided inside the treatment probe (4) on the upper side of the contact end (5), a terminal cooling assembly (7) for cooling the contact end (5), the optical treatment control module (9), and the ultrasound treatment control module (8) is installed outside the treatment probe (4), and an ultrasound imaging control module (6) is provided on the outer surface of the treatment probe (4).

2. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 1, characterized in that: The contact end (5) comprises a bottom sheet (51) and a top sheet (52), wherein the bottom sheet (51) and the top sheet (52) are both mounted on the lower opening of the treatment probe (4), and a cooling channel (53) is provided on the contact surface between the bottom sheet (51) and the top sheet (52), wherein one end of the cooling channel (53) is connected to an exhaust port (54), and the exhaust port (54) is provided outside the bottom sheet (51) and the top sheet (52), and the other end of the cooling channel (53) is connected to a terminal cooling assembly (7).

3. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 2, characterized in that: The terminal cooling assembly (7) includes an air pump (71), which is installed on the outside of the treatment probe (4). The air outlet of the air pump (71) is installed with an air duct (72), and the air duct (72) is communicated with the inside of the treatment probe (4). The treatment probe (4) is provided with an air outlet, and the air duct (72) is installed outside and communicated with an air pipe (73), and the end of the air pipe (73) is communicated with the other end of the cooling channel (53).

4. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 1, characterized in that: The adjustable cantilever (3) comprises a bracket (31), a rotating shaft (311) is fixedly mounted on the lower end of the bracket (31), a mounting seat (312) is rotatably connected to the lower end of the rotating shaft (311), and the mounting seat (312) is fixedly mounted on the outside of the diagnosis and treatment bed (2).

5. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 4, characterized in that: A transverse slide rail (32) is mounted on the upper end of the bracket (31), a movable seat (33) is fixedly mounted on the movable end of the transverse slide rail (32), a guide sleeve (34) is fixedly mounted on the lower end of the movable seat (33), a slide rod (35) is slidably mounted inside the guide sleeve (34), a vertical guide rail (36) is fixedly mounted on one end of the slide rod (35), a sliding member (37) is slidably mounted inside the vertical guide rail (36), and one end of the sliding member (37) is fixedly connected to the treatment probe (4).

6. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 5, characterized in that: A threaded hole (38) is provided through the sliding member (37), a threaded rod (39) is threadedly connected to the inside of the threaded hole (38), both ends of the threaded rod (39) are rotatably mounted inside the vertical guide rail (36), and the upper end of the threaded rod (39) is rotatably extended to the outside of the vertical guide rail (36) and is fixedly connected to a handle (40).

7. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 1, characterized in that: The ultrasonic treatment control module (8) includes an ultrasonic transmitter (81), a transducer, an ultrasonic power amplifier, and a temperature sensor in a circular array on the upper side of the top sheet (52). The ultrasonic transmitter (81), the transducer, the ultrasonic power amplifier, and the temperature sensor are electrically connected to a controller, and the controller is electrically connected to the host (1).

8. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 7, characterized in that: The optical therapy control module (9) includes a laser emitter (91) arranged at the center of the ultrasound emitter (81) array, and a spectrometer, a liquid crystal tunable filter, and a temperature monitoring sensor electrically connected to the laser emitter (91). The laser emitter (91), the spectrometer, the liquid crystal tunable filter, and the temperature monitoring sensor are electrically connected to the controller.

9. The high-frequency focused ultrasound combined with photodynamic therapy for uterine fibroid ablation according to claim 8, characterized in that: The ultrasound imaging control module (6) comprises an ultrasound probe (61) mounted outside the treatment probe (4), and a signal generator, a signal processor and a data recorder electrically connected to the ultrasound probe (61), and the ultrasound probe (61), the signal generator, the signal processor and the data recorder are electrically connected to the controller.

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