The invention discloses an online sizing and weighing system for a multi-flow multi-sizing continuous casting slab. The online sizing and weighing system is adopted, the weight of each casting slab is measured precisely, the weight and the part of which the weight deviation is set are converted into a sizing length modification valve, the sizing length value is amended continuously, fixed-weight cutting is achieved, and the weight of the casting slab is controlled in a reasonable range; a sizing and weighing device set is arranged on each flow, all flows are independent mutually, and the ejection waiting time caused by the flow amount is shortened; according to different sizing lengths, a plurality of weighing devices are arranged on each flow, and the number of the weighing device depends on the longest sizing required by production; a closed-loop control system is adopted for the multi-flow multi-sizing online sizing system. The system is high in automatic degree and stable to work, all the flows are independent mutually, the ejection waiting time caused by the flow amount is shortened, the influence of the weighing process on the production is small, the casting slab after passing through a roll gang can pass through the weighing roller way smoothly, and the system is simple and practical.