The invention relates to a micro-alloyed high-strength anti-oxidization iron-nickel alloy gas valve steel material and a preparation method. The material comprises elements such as Ni, Cr, Ti, Al, Mo, Nb, Mn, C, B, Mg, Ta, Ce, Zr, V, W, N, Fe and the like. The material can be used in a working environment with a high temperature, high load, strong oxidization and strong corrosion, is low in nickel content, has good tensile strength, good endurance strength, good fatigue strength and excellent oxidization resistance, good corrosion resistance and good resistance to fuel gas, and can be used for preparing a gas inlet valve and a gas outlet valve of a medium-high-load engine.