Method for producing and preparing 47Sc through irradiation of medium-high energy accelerator
By combining indirect and direct production methods, the 48Ca target is used to produce the parent isotope 47Ca in the middle energy section, and then 47Sc is generated by decay, and the optimal energy range is selected in the low energy section for direct production, solving the problem of low 47Sc yield in the prior art, achieving high yield and high purity 47Sc production.
Patent Information
- Application Number
- CN202510675124.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-23
- Publication Date
- 2025-08-29
AI Technical Summary
The prior art cannot increase the yield of 47Sc in the medium and high energy segments, and the reaction cross-section in the low energy segment is small, resulting in low production efficiency of 47Sc.
Using a combination of indirect and direct production, the 48Ca target is used to produce the parent isotope 47Ca in the middle energy section, and then 47Sc is generated by decay, and the optimal energy range is selected in the low energy section for direct production. Combined with 50Ti and 51V targets, the proportion of impurity nuclides is ensured to be low and the yield of 47Sc is increased.
Through the multi-stage cascade target, the accelerator energy is fully utilized to produce 47Sc with high yield and high purity to meet future market demand.
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Figure CN120565147A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of cyclotron radioisotope production, and specifically provides a method for improving the accelerator irradiation production and preparation 47 Sc yield method. Background Art
[0002] 47 Sc has a half-life of 3.35 days and emits β - The radiation (average energy 162keV) has a short- to medium-range therapeutic effect on target cells. - Outside the particles, 47 Sc also emits gamma rays at 159.4 keV (68.3%), which are suitable for SPECT imaging, so 47 Sc is ideal for radionuclide therapy and imaging. 47 Sc has great prospects for future development.
[0003] The reason why the yield of 47Sc cannot be improved by existing technology is that 47Sc is generally produced by only one target material (half-life 3.35 days), such as Figure 3 As shown in the figure, in the energy range of 30MeV-50MeV, although the 51V(p,x)47Sc reaction can also produce the target nuclide 47Sc, 45 / 46 / 48Sc isotope impurities will also be produced at the same time. According to industry common sense, isotope impurities cannot be removed by chemical separation methods. At the same time, in the energy range of 30MeV-50MeV, it is also impossible to reduce the proportion of 46Sc / 47Sc by natural decay. The reason is that Figure 3 In the energy range of 30MeV-50MeV, 46 The half-life of Sc is 83.79 days (the impurity nuclide 45Sc is a stable nuclide with no half-life, while the half-life of the impurity nuclide 48Sc is 1.82 days, which is less than the half-life of 47Sc (3.35 days). This is significantly longer than the half-life of the target nuclide 47Sc, which is 3.35 days. This is 25 times greater than the target nuclide's half-life of 3.35 days! Clearly, in the energy range of 30MeV-50MeV, the 46Sc / 47Sc ratio cannot be reduced through natural decay.
[0004] In summary, since the existing technology uses the 51V(p,x)47Sc method and natural decay in the medium and high energy range, it can only produce 47Sc in the low energy range of less than 30MeV. Therefore, the existing technology cannot increase the yield of the target nuclide 47Sc. Summary of the Invention
[0005] In order to solve the problems existing in the prior art, the present invention proposes a method for producing 47Sc by medium- and high-energy accelerator irradiation. The purpose is to solve the problem that the prior art adopts the 51V (p, x) 47Sc method and the natural decay method in the medium- and high-energy range, and can only produce 47Sc in the low-energy range of less than 30MeV, and the reaction cross section for producing 47Sc in the low-energy range of less than 30MeV is very small, which cannot increase the yield of the target nuclide 47Sc.
[0006] The present invention proposes the following method to solve the problems existing in the prior art:
[0007] A method for producing 47Sc by irradiation with a medium- or high-energy accelerator is characterized by comprising the following steps:
[0008] Step 1: Use the medium energy and low energy sections of the 50MeV high-current proton cyclotron to produce by indirect and direct production. 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target;
[0009] Step 2: In the medium energy range, 47Sc is produced by using an indirect target material. The indirect target material refers to the target material that reacts with protons to produce the parent isotope nuclide first, and then the parent isotope decays to produce the daughter isotope. 47 Sc;
[0010] Step 3: In the low energy range, 47Sc is produced using a target material that directly produces nuclides. The directly produced target material refers to the target material that is produced in the optimal energy range. 47 Sc, the optimal energy interval refers to the interval in which the isotopic impurities are relatively zero;
[0011] Furthermore, in the middle energy section of step 2, the target material for indirectly producing nuclides is used as the first target material. 48 Ca (p, d); in the step three, in the low energy section, the target material for directly producing nuclides is used as the second target material 51 V. Third target 50 Ti.
[0012] Furthermore, the first target material of the indirect production nuclide 48 Ca(p,d) produces 47Sc. The specific process is as follows:
[0013] 1) The proton accelerator produces 47Sc nuclide through 48Ca(p,d)47Ca→47Sc in the energy range of 30MeV-50MeV, and the beam is incident on a 13.7mm thick 48 Ca target, through 48 Ca(p,d)47 Ca reactions produce parent isotopes 47 Ca, and then through the parent isotope 47 Ca / 47 Sc generator production 47 Sc, out 48 After the Ca target, the proton energy is 20 MeV;
[0014] 2) Parent isotope 47 The half-life of Ca is 4.536 days, and it is transported through β - decay, by 47 Ca changes to daughter isotopes 47 Sc, and then extract the daughter by chemical separation.
[0015] Furthermore, the target nuclide 47Sc is produced by using the second target material 51V for directly producing nuclides. The specific process is as follows: after passing through the 48Ca target, the proton energy is 30MeV. In order to ensure a low Sc / 47Sc ratio while taking into account the 47Sc yield, at this time, when the proton accelerator is in the energy range of 20-30MeV, the thickness of the 51V target is set to 1.14mm, and the 47Sc nuclide is produced through the 51V(p,x)47Sc reaction.
[0016] Furthermore, the proton accelerator produces 47Sc nuclides through the 51V(p,x)47Sc reaction in the energy range of 20-30MeV. The specific process is as follows:
[0017] 1) Confirm 51 The range of impurity nuclides produced by the reaction between the V target and the proton is 30-50 MeV, and the range of impurity nuclides not produced is 20-30 MeV;
[0018] 2) Select 51 The V target relatively does not produce impurity nuclides in the range of 20-30MeV as the optimal production energy range for production 47 Sc.
[0019] Furthermore, the third target material used to directly produce nuclides 50 Ti produces the target nuclide 47Sc. The specific process is as follows: after passing through the 51V target, the proton energy is 20MeV. The proton accelerator produces 47Sc nuclide through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV. At this time, the target thickness is 1.19mm.
[0020] Furthermore, the proton accelerator produces 47Sc nuclides through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV, as follows:
[0021] 1) Determine that the range of relative production of impurity nuclides after the reaction of 50Ti target with protons is 20-30 MeV, and the range of relative non-production of impurity nuclides is 8-20 MeV;
[0022] 2) Select the range of 8-20MeV which is relatively free of impurity nuclides as the optimal production energy range for production 47 Sc.
[0023] Furthermore, the method also includes using the medium energy segment and low energy segment of the 50MeV deuterium cyclotron to produce the 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target.
[0024] Furthermore, in the medium energy range of 26MeV-50MeV, 47Sc is indirectly produced by producing 47Ca through the 48Ca(d,t)47Ca reaction.
[0025] Furthermore, in the low energy range of 15MeV-26MeV, high-purity 47Sc products can be directly produced through the 50Ti(d,αn)47Sc reaction, and 47Sc can be directly produced through the 49Ti(d,x)47Sc reaction at 4MeV-12MeV.
[0026] Advantages and effects of the present invention
[0027] 1. This invention produces 47Sc directly or indirectly through a multi-stage cascade target system, fully utilizing the energy of medium- and high-energy accelerators. The 47Sc produced by the generator is free of isotopic impurities such as 46Sc and 48Sc. When directly producing 47Sc through proton irradiation, this invention ensures a low percentage of isotopic impurities such as 46Sc and 48Sc while also ensuring a high yield of 47Sc. Consequently, the 47Sc produced by this invention offers the advantages of high yield and purity, meeting future market demand.
[0028] 2. This invention fully utilizes the energy of the accelerator to produce the target nuclide 47Sc not only through the reaction of protons with the target material, but also through the reaction of deuterons, alpha particles, and other heavy ions with the target material. This method offers the advantages of high yield and high purity, which can meet future market demand. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 Schematic diagram of proton beam incident on 48Ca target, 51V and 50Ti target in sequence;
[0030] Figure 2a Reaction cross sections for the reaction between 48Ca target and protons to produce 47Ca and 45Ca;
[0031] Figure 2b Schematic diagram of 47Ca decay to produce 47Sc;
[0032] Figure 3 Reaction cross sections for the production of 47Sc, 45Sc, 46Sc, and 48Sc from a 51V target and protons;
[0033] Figure 4 Reaction cross sections for the production of 47Sc, 46Sc, and 48Sc from a 50Ti target and protons.
[0034] Figure 5 The present invention is a flow chart of a method for producing 47Sc by irradiation using a medium- to high-energy accelerator. DETAILED DESCRIPTION
[0035] Design principle of the present invention
[0036] 1. Innovation of the present invention
[0037] One of the innovations is the combination of indirect and direct production methods, which solves the problem that existing technologies can only produce 47Sc in the low energy range below 30MeV, while the energy range above 30MeV cannot be utilized, resulting in the inability to increase the yield of the target nuclide 47Sc.
[0038] The second innovation is to adopt a method of combining the low energy zone and the optimal energy zone, which solves the problem that the reaction cross section of the existing technology in the low energy zone is very small, only less than 6mb.
[0039] 2. Design Principle of the Invention
[0040] First, the design principle of combining indirect production with direct production. Figure 2a 、 Figure 2b As shown, using 48Ca target, an indirect method of producing 47Sc is adopted in the 30MeV-50MeV region; Figure 3 As shown, a method for directly producing 47Sc is used in the energy range of 20-30MeV using a 51V target; Figure 4 As shown, using 50 Ti target material, using a direct production method of 47Sc in the energy range of 8-20MeV. The method of producing 47Sc by an indirect production method in the medium energy range means that the target material reacts with protons to first produce the parent isotope nuclide 47Ca, and then the parent isotope 47Ca decays to produce the daughter isotope 47Sc;
[0041] The principle of indirect production of 47Sc in the medium energy range is as follows Figure 2a 、 Figure 2b As shown, using48 Ca target indirectly produces 47Sc in the energy range of 30MeV-50MeV. Although impurity nuclide 45Ca is also produced in the energy range of 30MeV-50MeV, after one day of irradiation, the purity of 47Ca radionuclides is 99.04%, while the purity of impurity nuclide 45Ca radionuclides is 0.96%. Since 47Ca nuclides account for 99%, it has met the set requirements. 47 Ca / 47 Sc generator produced 47 Sc, 47 The Ca half-life is much shorter than 45 Ca, an isotope with a small half-life decays quickly, so 47 Ca decay 47 The rate of Sc is much greater than 45 Ca decay 45 Sc, so the decay produces 47 Sc nuclides meet the demand. (Through 45 Ca decay 45 Sc is a stable isotope and will not affect 47 The radioactive purity of Sc only affects its specific activity. After 47Ca decay is complete, the 47Sc produced via the parent isotope 47Ca / 47Sc generator also accounts for 99%. In short, this indirect production method fills the energy range of 30MeV-50MeV for 51V targets, resolving the problem of obtaining 47Sc with a radioactive purity greater than 99% in this energy range due to the inability to reduce the 46Sc / 47Sc ratio through natural decay.
[0042] Second, one of the principles of combining low energy zone and optimal energy zone to increase yield is: Figure 3 As shown in the figure, in the high-yield range of 20MeV-30MeV, the target nuclide 47Sc is directly produced using a 51V target. Although the 51V target has a yield in the 20MeV-50MeV range, impurities including 46Sc are produced in the 30MeV-50MeV range. Since the half-life of 46Sc is 83.79 days, which is much longer than the half-life of the target nuclide 47Sc of 80.2 hours, the 20MeV-30MeV energy range, where relatively no impurity nuclides are produced, is the optimal energy range to increase the yield of 47Sc.
[0043] Third, the second principle of combining low energy zone and optimal energy zone to increase yield: Figure 4As shown in the figure, in the low energy range of 8-20MeV, the target nuclide 47Sc is directly produced by 50Ti target. Although 50Ti target has a yield in the range of 8MeV-27MeV, impurity nuclides including 46Sc are produced in the range of 19MeV-27MeV. Since the half-life of 46Sc is 83.79 days, which is much longer than the half-life of the target nuclide 47Sc, 8MeV-27MeV, where relatively no impurity nuclides are produced, can only be selected as the optimal energy range in order to increase the yield of 47Sc. In short, the present invention adopts indirect production. 47 Sc and direct production 47 The combined method of Sc fills the existing technology which generally only produces by one target material. 47 Sc leads to 47 The disadvantages of Sc are low yield and not suitable for production in medium and high energy accelerators; 48 Indirect production of Ca targets 47 Sc, using 51V target and 50Ti target in the low energy zone, respectively select the energy zone without impurities of 51V target and 50Ti target as the best energy zone for producing 47Sc, thereby increasing the yield of 47Sc.
[0044] Based on the above invention principle, the present invention designs a method for producing 47Sc by medium-high energy accelerator irradiation, such as Figure 5 As shown, its characteristics are: comprising the following steps:
[0045] Step 1: Use the medium energy and low energy sections of the 50MeV high-current proton cyclotron to produce by indirect and direct production. 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target;
[0046] Step 2: In the medium energy range, 47Sc is produced by using an indirect target material. The indirect target material refers to the target material that reacts with protons to produce the parent isotope nuclide first, and then the parent isotope decays to produce the daughter isotope. 47 Sc;
[0047] Step 3: In the low energy range, 47Sc is produced using a target material that directly produces nuclides. The directly produced target material refers to the target material that is produced in the optimal energy range. 47 Sc, the optimal energy range refers to the range in which the isotopic impurity ratio is less than 1%;
[0048] Furthermore, in the middle energy section of step 2, the target material for indirectly producing nuclides is used as the first target material. 48 Ca (p, d); in the step three, in the low energy section, the target material for directly producing nuclides is used as the second target material51 V. Third target 50 Ti.
[0049] like Figure 1 、 Figure 2a 、 Figure 2b As shown, the first target material of the indirect production nuclide 48 Ca(p,d) produces 47Sc. The specific process is as follows:
[0050] 1) The proton accelerator produces 47Sc nuclide through 48Ca(p,d)47Ca→47Sc in the energy range of 30MeV-50MeV, and the beam is incident on a 13.7mm thick 48 Ca target, through 48 Ca(p,d) 47 Ca reactions produce parent isotopes 47 Ca, and then through the parent isotope 47 Ca / 47 Sc generator production 47 Sc, out 48 After the Ca target, the proton energy is 20 MeV;
[0051] 2) Parent isotope 47 The half-life of Ca is 4.536 days, and it is transported through β - decay, by 47 Ca changes to daughter isotopes 47 Sc, and then extract the daughter by chemical separation.
[0052] like Figure 3 As shown, the second target material 51V for directly producing nuclides is used to produce the target nuclide 47Sc. The specific process is as follows: after passing through the 48Ca target, the proton energy is 30MeV. In order to ensure a low Sc / 47Sc ratio while taking into account the 47Sc yield, at this time, when the proton accelerator is in the energy range of 20-30MeV, the thickness of the 51V target is set to 1.14mm, and the 47Sc nuclide is produced through the 51V(p,x)47Sc reaction.
[0053] like Figure 3 As shown, the proton accelerator produces 47Sc nuclides through the 51V(p,x)47Sc reaction in the energy range of 20-30MeV. The specific process is as follows:
[0054] 1) Confirm 51 The range of impurity nuclides produced by the reaction between the V target and the proton is 30-50 MeV, and the range of impurity nuclides not produced is 20-30 MeV;
[0055] 2) Select 51The V target relatively does not produce impurity nuclides in the range of 20-30MeV as the optimal production energy range for production 47 Sc.
[0056] like Figure 4 As shown, the third target material used to directly produce nuclides 50 Ti produces the target nuclide 47Sc. The specific process is as follows: after passing through the 51V target, the proton energy is 20MeV. The proton accelerator produces 47Sc nuclide through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV. At this time, the target thickness is 1.19mm.
[0057] like Figure 4 As shown, the proton accelerator produces 47Sc nuclides through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV, as follows:
[0058] 1) Determine that the range of relative production of impurity nuclides after the reaction of 50Ti target with protons is 20-30 MeV, and the range of relative non-production of impurity nuclides is 8-20 MeV;
[0059] 2) Select the range of 8-20MeV which is relatively free of impurity nuclides as the optimal production energy range for production 47 Sc.
[0060] Furthermore, the method also includes using the medium energy segment and low energy segment of the 50MeV deuterium cyclotron to produce the 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target.
[0061] Furthermore, in the medium energy range of 26MeV-50MeV, 47Sc is indirectly produced by producing 47Ca through the 48Ca(d,t)47Ca reaction.
[0062] Furthermore, in the low energy range of 15MeV-26MeV, high-purity 47Sc products can be directly produced through the 50Ti(d,αn)47Sc reaction, and 47Sc can be directly produced through the 49Ti(d,x)47Sc reaction at 4MeV-12MeV.
[0063] Example 1:
[0064] Taking the 50MeV high-current proton cyclotron as an example, 47Sc is produced by two methods: direct production and indirect production by generator. Figure 2a 、 Figure 2bThis is the reaction cross section for the production of 47Ca from a 48Ca target and protons. Monte Carlo simulations show that a 50MeV proton beam generated by an accelerator is first incident on a 13.7mm thick 48Ca target, where 47Ca is produced via the 48Ca(p,d)47Ca reaction. 47Ca has a half-life of 4.536 days and can decay into 47Sc through β-decay. Isotope generators operate by decaying a parent isotope to produce daughter isotopes, which are then extracted through chemical separation. Therefore, 47Ca produced in an accelerator can be converted to 47Sc using a 47Ca / 47Sc generator. The production energy range is 30MeV-50MeV. After one day of irradiation, the radioactive purity of 47Ca is 99.04%, and that of 45Ca is 0.96%.
[0065] After passing through the 48Ca target, the proton energy is 30MeV. In order to ensure a low Sc / 47Sc ratio while taking into account the 47Sc yield, a 51V target with a target thickness of 1.14mm is selected at this time, and 47Sc is produced through the 51V(p,x)47Sc reaction.
[0066] After passing through the 51V target, the proton energy is 20MeV. At this time, the 50Ti target is selected and 47Sc is produced through the 50Ti(p,x)47Sc reaction. Figure 5 As shown, in order to ensure a low Sc / 47Sc ratio while taking into account the 47Sc yield, the optimal production energy range is 8-20MeV and the target thickness is 1.19mm.
[0067] Example 2:
[0068] Cyclotrons can produce electrons, protons, deuterons, alpha particles, and other heavy ions of various energies. Taking a 50MeV deuterium cyclotron as an example, 47Sc can be produced through two methods: direct production and indirect production via a generator. In the 26MeV-50MeV energy range, 47Sc is indirectly produced by the 48Ca(d,t)47Ca reaction. High-purity 47Sc is directly produced through the 50Ti(d,αn)47Sc reaction at 15MeV-26MeV. And 47Sc is directly produced through the 49Ti(d,x)47Sc reaction at 4MeV-12MeV, effectively and fully utilizing the accelerator's energy.
[0069] The present invention produces by multi-stage cascade target 47 Sc, make full use of the energy of the accelerator and reduce the main impurity nuclides through reasonable energy selection 45 / 46 / 48 Sc ratio, improve 47 Sc's output to meet future market product demand.
[0070] It should be emphasized that the above specific embodiments are merely explanations of the present invention and are not limitations of the present invention. After reading this specification, those skilled in the art may make non-creative modifications to the above embodiments as needed, but as long as they are within the scope of the claims of the present invention, they are protected by patent law.
Claims
1. A medium- and high-energy accelerator irradiation production 47 The method of Sc, characterized in that: The following steps are involved: Step 1: Use the medium energy and low energy sections of the 50MeV high-current proton cyclotron to produce by indirect and direct production. 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target; Step 2: In the medium energy range, use the target material production of indirect production nuclides 47 Sc, the indirect production target material refers to the target material and protons react to produce the parent isotope nuclide first, and then the parent isotope decays to produce the daughter isotope 47 Sc; Step 3: In the low energy range, use the target material to directly produce nuclides 47 Sc, the target material produced directly refers to the target material produced by the optimal energy range 47 Sc, the optimal energy range refers to the range in which the isotope impurity ratio is less than 1%.
2. A medium- and high-energy accelerator irradiation production according to claim 1 47 The method of Sc, characterized in that: In the middle energy section of step 2, the target material for indirect production of nuclides is the first target material. 48 Ca (p, d); in the step three, in the low energy section, the target material for directly producing nuclides is used as the second target material 51 V. Third target 50 Ti.
3. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 2, characterized in that: The first target material of the indirect production nuclide 48 Ca(p,d) produces 47Sc. The specific process is as follows: 1) The proton accelerator produces 47Sc nuclide through 48Ca(p,d)47Ca→47Sc in the energy range of 30MeV-50MeV, and the beam is incident on a 13.7mm thick 48 Ca target, through 48 Ca(p,d) 47 Ca reactions produce parent isotopes 47 Ca, and then through the parent isotope 47 Ca / 47 Sc generator production 47 Sc, out 48 After the Ca target, the proton energy is 30 MeV; 2) Parent isotope 47 The half-life of Ca is 4.536 days, and it is transported through β - decay, by 47 Ca changes to daughter isotopes 47 Sc, and then extract the daughter by chemical separation.
4. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 2, characterized in that: The specific process of using the second target material 51V to directly produce the target nuclide 47Sc is as follows: 48 After the Ca target, the proton energy is 30MeV, in order to ensure a low Sc / 47Sc ratio while taking into account 47 Sc yield, at this time, in the proton accelerator in the energy range of 20-30MeV, 51 The thickness of the V target is set to 1.14 mm, and the 47Sc nuclide is produced through the 51V(p,x)47Sc reaction.
5. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 4, characterized in that: The proton accelerator produces 47Sc nuclides through the 51V(p,x)47Sc reaction in the energy range of 20-30MeV. The specific process is as follows: 1) Confirm 51 The range of relative production of impurity nuclides after the reaction between the V target and the proton is 30-50 MeV, and the range of relative non-production of impurity nuclides is 20-30 MeV; 2) Select 51 The V target relatively does not produce impurity nuclides in the range of 20-30MeV as the optimal production energy range for production 47 Sc.
6. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 2, characterized in that: The third target material used to directly produce nuclides 50 Ti produces the target nuclide 47Sc. The specific process is as follows: after passing through the 51V target, the proton energy is 20MeV. The proton accelerator produces 47Sc nuclide through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV. At this time, the target thickness is 1.19mm.
7. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 6, characterized in that: The proton accelerator produces 47Sc nuclides through the 50Ti(p,x)47Sc reaction in the energy range of 8-20MeV, as follows: 1) Determine that the range of relative production of impurity nuclides after the reaction of 50Ti target with protons is 20-30 MeV, and the range of relative non-production of impurity nuclides is 8-20 MeV; 2) Select the range of 8-20MeV, which is relatively free of impurity nuclides, as the optimal production energy range for production 47 Sc.
8. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 1, characterized in that: The method also includes using the medium energy segment and low energy segment of the 50MeV deuterium nuclear cyclotron to produce indirect and direct production. 47 Sc, and indirectly produced 47 Sc targets and direct production 47 The target material of Sc constitutes a composite target.
9. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 8, characterized in that: In the medium energy range of 26MeV-50MeV, 47Sc is indirectly produced by producing 47Ca through the 48Ca(d,t)47Ca reaction.
10. The method for producing 47Sc by medium- and high-energy accelerator irradiation according to claim 8, characterized in that: In the low energy range of 15MeV-26MeV, high-purity 47Sc products are directly produced through the 50Ti(d,αn)47Sc reaction, and 47Sc is directly produced through the 49Ti(d,x)47Sc reaction at 4MeV-12MeV.