Use of butyric acid-producing enterobacteriaceae as probiotic against eimeria tenella

By using *Enterobacter butyrate-producing* DSM 26588 and its culture supernatant, the problems of *Eimeria tenella* invasion and intestinal lesions were solved, the disease resistance of chickens was improved, and effective anticoccidial protection was achieved.

CN120570920BActive Publication Date: 2026-04-10JILIN AGRICULTURAL UNIV
1 Cites 0 Cited by

Patent Information

Application Number
CN202510722776.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-05-30
Publication Date
2026-04-10
Estimated Expiration
2045-05-30

AI Technical Summary

Technical Problem

In the existing technology, there is little research on the effects of butyrate-producing Enterobacter on intestinal parasites such as Eimeria tenella, especially its application as a probiotic has not been fully explored, leading to a high incidence of coccidiosis in chickens and high economic losses.

Method used

Using *Enterobacter butyrate-producing* DSM 26588 and its culture supernatant, related products were prepared to reduce oocyst excretion and intestinal lesions, thereby improving the disease resistance of chickens by inhibiting the invasion of *Eimeria tenella* sporozoites, regulating immune responses, and improving intestinal health.

Benefits of technology

It effectively inhibits the invasion of Eimeria tenella, increases the weight and survival rate of chicks, reduces oocyst excretion, reduces intestinal lesions, enhances immune response, and achieves good anti-coccidial effects.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The present application relates to the field of microbial technology, and particularly relates to the application of butyric acid-producing Enterobacter as an anti-Eimeria tenella probiotic. In the present application, the E. tenella infection model induced by an antibiotic cocktail is used to explore the effect of butyric acid-producing Enterobacter DSM 26588 on the development of E. tenella. The butyric acid-producing Enterobacter DSM 26588 inhibits the expression of the EtGFAT gene of the gamete of E. tenella, thereby inhibiting the development of the gamete; improves the intestinal lesions caused by E. tenella infection, reduces the pathological damage to the intestine, and reduces the output of E. tenella oocysts, with an ACI value of 162, and has good anti-coccidial effect.
Need to check novelty before this filing date? Find Prior Art