Traditional Chinese medicine composition for treating chronic lumbar muscle strain

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating chronic lumbar muscle strain. The traditional Chinese medicine composition comprises 10-20 parts of eucommia ulmoides, 10-15 parts of philippine flemingia root, 10-20 parts of radix cyathulae, 5-10 parts of radix angelicae pubescentis, 10-20 parts of lycianthes biflora, 5-10 parts of semen coicis, 10-20 parts of roughhaired holly, 5-10 parts of poria cocos and 15-20 parts of herba leonuri. According to the etiology and pathogenesis of kidney deficiency, rheumatism, qi stagnation, blood stasis and the like and in combination with diseases, the traditional Chinese medicine composition has the effects of tonifying kidney and strengthening tendons, dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis and regulating qi-flowing for eliminating phlegm, and meanwhile, can regulate and nourish liver and kidney, dredge joints, promote qi circulation and harmonize blood, and achieves the effects of relaxing tendons and activating collaterals, and reinforcing kidney and nourishing blood. The traditional Chinese medicine composition is rigorous in medicine use, has reinforcing and reducing functions, harmonizes and tonifies the middle warmer, can clear damp and remove turbidity, can tonify qi and reduce phlegm, and is suitable for symptoms such as deficiency of liver and kidney, rheumatic arthralgia and meridian stasis. And the traditional Chinese medicine composition also has a good promotion effect on postoperative rehabilitation of related diseases.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and more specifically, relates to a traditional Chinese medicine composition for treating chronic lumbar muscle strain. Background Art

[0002] Chronic lumbar muscle strain (CLMS) is a chronic overuse disease characterized by lower back discomfort and pain as its primary clinical symptoms. It is also known as lumbar and gluteal myofasciitis, functional low back pain, and chronic low back injury. Western medicine treatments for mild pain are primarily based on oral medications such as nonsteroidal anti-inflammatory drugs, while more severe pain is often treated with hydrocortisone acetate pain point blockades and topical analgesics. These treatments are relatively simple and have a good short-term effect, but long-term use can lead to reduced efficacy and increased adverse reactions, resulting in recurrence and an incurable disease. The recurrence rate after discontinuation of medication is extremely high. Traditional Chinese medicine (TCM) is more effective in intervening in this disease, and traditional treatments such as Chinese medicine, acupuncture, fumigation, analgesic ointments, and massage are generally used to alleviate low back pain symptoms with fewer adverse reactions. Topical application of TCM is currently one of the unique therapies in TCM. Compared with traditional oral medications, topical medications are absorbed through the skin and can reduce adverse reactions. The Chinese herbal powders mentioned in the Compendium of Materia Medica are often ground into a fine powder and sprinkled on the affected area for a local therapeutic effect. Alternatively, they can be applied with sesame oil, honey, wine, vinegar, or other ingredients. This topical powder therapy, developed through the continuous clinical practice of successive physicians, has become widely used in clinical practice.

[0003] The mechanism of action of topical application of traditional Chinese medicine powders for CLMS is transdermal absorption of the drug through the skin, directly reaching the affected area, thereby accelerating the circulation of qi and blood, promoting local organic matter metabolism, relieving pain, and promoting the recovery of physiological functions in the lower back. However, existing traditional Chinese medicine formulas for lumbar muscle strain often suffer from significant side effects or are unsuitable for topical application. Summary of the Invention

[0004] To overcome the deficiencies of the prior art, the present invention aims to provide a traditional Chinese medicine composition for treating chronic lumbar muscle strain. This composition is simple, easy to use, effective, safe, reliable, and highly adaptable, enabling precise dosing. It is beneficial in supplementing clinical treatment methods, alleviating patients' symptoms, and improving clinical cure rates while avoiding the side effects of long-term Western medication, thereby enhancing patient medication compliance and quality of life.

[0005] The purpose of the present invention is achieved through the following technical solutions:

[0006] A traditional Chinese medicine composition for treating chronic lumbar muscle strain comprises the following substances in parts by weight: 10-20 parts of Eucommia ulmoides, 10-15 parts of Tripterygium wilfordii, 10-20 parts of Cyathula capitata, 5-10 parts of Angelica dahurica, 10-20 parts of Red Silk Thread, 5-10 parts of Coix seeds, 10-20 parts of Prunus mume, 5-10 parts of Poria cocos, and 15-20 parts of Leonurus japonicus.

[0007] Preferably, the above-mentioned traditional Chinese medicine composition is composed of the following substances in parts by weight: 15 parts of Eucommia ulmoides, 20 parts of Tripterygium wilfordii, 10 parts of Angelica dahurica, 15 parts of Rhizoma Cibotii, 20 parts of Poria cocos, 20 parts of Cyathula capitata, 5 parts of red silk thread, 30 parts of Coix seeds, and 15 parts of Leonurus japonicus.

[0008] In the above-mentioned Chinese medicine composition of the present invention, the functions of each Chinese medicine are as follows:

[0009] Eucommia ulmoides: Sweet, slightly pungent, and warm. It enters the liver and kidney meridians. It nourishes the liver and kidneys, strengthens the bones and tendons, and stabilizes pregnancy. It is primarily used to treat lower back pain and weakness of the feet and knees. The flavonoids and iridoids in Eucommia ulmoides inhibit inflammatory factors and have analgesic properties, alleviating aseptic inflammation in the lower back. They also dilate blood vessels, improve microcirculation in the lower back, accelerate the clearance of metabolites, and relieve muscle spasms and hypoxia. Modern pharmacology shows that Eucommia ulmoides has demonstrated efficacy in inhibiting inflammation, dilating blood vessels, and improving circulation.

[0010] Rhizoma Coptidis: Sweet, slightly astringent, and neutral in nature; it enters the Liver and Kidney Meridians. It dispels wind and dampness, strengthens tendons and bones, and activates blood circulation and detoxifies. It is primarily used to treat rheumatic pain, lumbar muscle strain, limb weakness, and traumatic injuries. Modern research indicates that the flavonoids in Rhizoma Coptidis inhibit the NF-κB signaling pathway, reducing the release of proinflammatory cytokines (such as IL-1, IL-6, and TNF-α) while enhancing the expression of autophagy-related proteins (such as Beclin-1 and LC3II / LC3Ⅰ). Rhizoma Coptidis demonstrates a clear repair effect on a rat sciatic nerve injury model, improving nerve conduction velocity, motor function index, and reducing nerve fiber swelling. It exhibits anti-inflammatory and microcirculatory-enhancing effects, inhibiting the release of inflammatory factors, relieving muscle spasms and local hypoxia, alleviating local aseptic inflammatory responses, and alleviating pain. It also dilates blood vessels and improves lumbar microcirculation, thereby achieving an analgesic effect.

[0011] Duhuo (Radix Angelicae Pubescentis): Pungent and bitter in flavor, slightly warm in nature. It enters the kidney and bladder meridians. It dispels wind and dampness, relieves numbness, and relieves pain. Indications: It is used for wind-cold-dampness arthritis, and pain in the waist and knees. Duhuo (Radix Angelicae Pubescentis) is good at removing long-standing numbness and has a downward-moving nature. It is particularly effective at treating wind-cold-dampness in the lower abdomen, dispelling numbness and relieving pain, especially pain in the waist, knees, legs, and feet. Modern research has shown that decoctions or extracts of Duhuo (Radix Angelicae Pubescentis) have sedative, analgesic, and hypnotic effects on mice, and have a transient antihypertensive effect on cardiovascular and cerebrovascular systems. Animal experiments, through repeated isolation and activity tracking, have shown that Duhuo (Radix Angelicae Pubescentis) has significant inhibitory activity against platelet aggregation and inflammatory substances in rats in vitro.

[0012] Herba Artemisiae Arnebiae: Bitter, slightly sweet, and cooling in nature, it enters the Lung and Stomach Meridians. It clears heat and toxins, dissipates blood stasis, and relieves pain. It is primarily used to treat pain caused by traumatic injuries, carbuncles, and sores. External application can alleviate carbuncles and sores. Its heat-clearing, detoxifying, and blood stasis-dispersing properties can also improve lower back pain caused by damp-heat. Modern research indicates that Herba Artemisiae Arnebiae contains triterpenoid saponins and alkaloids that inhibit Staphylococcus aureus and Streptococcus. Its flavonoids also promote the removal of metabolic waste, possessing antioxidant and immunomodulatory properties. It can effectively improve circulation in the lower back and inhibit the production of inflammatory substances.

[0013] Poria: sweet, light in taste, neutral in nature. It enters the heart, lung, spleen, and kidney meridians. It has the effects of promoting diuresis and dispelling dampness, strengthening the spleen, and calming the mind. It is used for spleen deficiency and dampness. Poria contains a variety of chemical components such as polysaccharides, diterpenes, triterpenes, sterols, phosphates, etc., and shows good biological activity. Modern pharmacological research mainly includes: antioxidant, anti-inflammatory, anti-tumor, immune regulation, kidney protection, cardioprotection, liver protection and other effects. The Poria polysaccharide in Poria has anti-inflammatory and antioxidant effects, can reduce the level of inflammatory factors (such as TNF-α), and reduce oxidative damage to the lumbar muscles. Its diuretic effect can accelerate the disappearance of edema and relieve swelling and pain in the waist.

[0014] Sichuan Cyathula: Bitter, sweet, sour, and neutral in nature. It enters the liver and kidney meridians, primarily promoting blood circulation and removing blood stasis, nourishing the liver and kidneys, and promoting diuresis and relieving stranguria. It is effective for conditions such as soreness of the waist and knees. Modern research indicates that Achyranthes contains flavonoids, sterols, triterpenoid saponins, polysaccharides, and amino acids. Components such as cyasterone and ecdysterone in Sichuan Cyathula can block the NF-κB signaling pathway, reduce levels of inflammatory factors such as TNF-α and IL-6, alleviate aseptic inflammatory responses, and reduce prostaglandin production by inhibiting cyclooxygenase (COX-2), thereby relieving pain. Flavonoids and phenolic acids, through their antioxidant properties, reduce oxidative damage to muscle cells, slowing the progression of strain injuries.

[0015] Red silk thread: Sweet, light, and cooling in nature; it enters the lung meridian. Its primary functions include clearing the lungs and relieving coughs, dispersing blood stasis, and reducing swelling. It is primarily used to treat lung-heat coughs and traumatic injuries. Its leaves, when crushed, become red and filamentous when exposed to water. Topical application can promote blood circulation and dissipate blood stasis. Modern pharmacological studies have shown that red silk thread, containing lupeol and β-sitosterol, has antihypertensive, lipid-regulating, and immunomodulatory effects. Red silk thread extract has been shown to increase thymus and spleen weight in mice, enhance macrophage phagocytic activity, and serum hemolysin antibody production, thereby enhancing immune function. Flavonoids mitigate oxidative stress by scavenging free radicals (e.g., reducing malondialdehyde levels). They can increase serum nitric oxide synthase (NOS) activity and NO concentration, dilate vascular smooth muscle, and inhibit endothelin (ET) release, improving endothelial function and promoting blood circulation.

[0016] Coix seed: sweet, light in taste, cool in nature. It enters the spleen, stomach, and lung meridians. It has the effects of promoting water expelling dampness, strengthening the spleen and stopping diarrhea, removing numbness, draining pus, and detoxifying and dispersing stagnation. Traditional Chinese medicine believes that "dampness is heavy and turbid", and dampness blocking the waist can aggravate soreness and stiffness. Coix seed can improve this type of dampness and blood stasis type of low back pain. Coix seed extract increases local blood flow by dilating capillaries, accelerating the removal of metabolic waste (such as lactic acid). At the same time, its antioxidant components (such as phenolic acids) reduce the oxidative damage of free radicals to muscle cells and delay the progression of strain. Coix seed polysaccharides have multiple effects such as hypoglycemic, anti-tumor, anti-inflammatory, and antioxidant. Modern research shows that coix seed polysaccharides have anti-inflammatory and analgesic effects, can reduce the number of twisting times in mice, increase the pain threshold, and relieve the degree of swelling caused by acute inflammation. On this basis, the extracted crude polysaccharide was further separated and purified to obtain a compound, and it was found that it had a good inhibitory effect on LPS (Lipopolysaccharide)-induced RAW264.7 cell inflammation.

[0017] Motherwort: Bitter, pungent, and slightly cold. It enters the liver, pericardium, and bladder meridians. It promotes blood circulation and regulates menstruation, promotes diuresis and reduces swelling, and clears away heat and detoxifies. Its effects on blood circulation and menstruation are known to improve lumbar blood circulation and alleviate local blood stasis and metabolic waste accumulation caused by long-term strain. It contains chemical components such as alkaloids, flavonoids, and diterpenes, exhibiting antioxidant, anti-apoptotic, anti-inflammatory, and analgesic effects. Motherwort primarily contains leonurine, stachydrine, flavonoids, and polysaccharides. Leonurine exerts anti-inflammatory effects by inhibiting inflammatory signaling pathways (such as NF-κB), while stachydrine regulates vascular tone and improves local blood flow. Using a hot plate test in mice, Wang Lijuan et al. found that motherwort prolongs the pain threshold to heat stimulation in mice. Using a chemical stimulation test, they found that motherwort reduces writhing in mice and inhibits xylene-induced ear swelling in mice and carrageenan-induced plantar swelling in rats, demonstrating that motherwort possesses significant analgesic and anti-inflammatory properties.

[0018] Preferably, the above-mentioned Chinese medicine composition further comprises auxiliary materials, specifically ginger juice, white vinegar, and honey.

[0019] The present invention also provides use of the traditional Chinese medicine composition in preparing medicine for chronic lumbar muscle strain.

[0020] The present invention also provides a method for preparing a traditional Chinese medicine cake for treating chronic lumbar muscle strain, comprising mixing the components of the traditional Chinese medicine composition, grinding and sieving to obtain powder of the traditional Chinese medicine composition, adding ginger juice or vinegar to the powder of the traditional Chinese medicine composition, blending the mixture evenly, and pressing the mixture into a cake shape.

[0021] Preferably, in the above preparation method, the grinding is followed by sieving to 80-120 mesh.

[0022] The traditional Chinese medicine cake prepared by the present invention can be applied to acupoints such as Shenshu, Dachangshu, Guanyuan, Yaoyangguan, Zhibian and Yanglingquan to treat chronic lumbar muscle strain with significant therapeutic effect.

[0023] Compared with the prior art, the present invention has the following beneficial effects:

[0024] Based on the pathogenesis of kidney deficiency, rheumatism, and qi stagnation and blood stasis, this prescription, combined with the symptoms, has the effects of tonifying the kidneys and strengthening the tendons, dispelling wind and dampness, promoting blood circulation and removing blood stasis, regulating qi and resolving phlegm. It also nourishes the liver and kidneys, unblocks the joints, and promotes qi and blood circulation, achieving the effects of relaxing tendons and activating collaterals, strengthening the kidneys and nourishing blood. This prescription uses rigorous medication, combining tonification and purgation, harmonizing while promoting circulation and promoting tonification. It can dispel dampness and clear turbidity, while also invigorating qi and resolving phlegm. It is suitable for symptoms such as liver and kidney deficiency, rheumatic pain, and meridian stasis. It also significantly promotes postoperative recovery from related conditions.

[0025] The combination of Eucommia ulmoides, Radix Achyranthis Bidentatae, and Rhizoma Cynoglossi in this formula tonifies the kidneys and strengthens the tendons, benefits the liver and nourishes the blood, and relaxes the tendons and activates the collaterals. Eucommia ulmoides nourishes the kidneys and improves essence, strengthens the tendons and bones, and is particularly effective for treating soreness and weakness of the lower back and knees; Radix Achyranthis Bidentatae nourishes the liver and kidneys, strengthens the tendons and bones, and dispels rheumatism, effectively treating low back pain and rheumatic pain caused by liver and kidney deficiency; Rhizoma Cynoglossi promotes blood circulation and unblocks the collaterals, strengthens the tendons and bones, and also has the effect of guiding the downward movement of the herbs. The three herbs work synergistically to tonify the kidneys, activate blood circulation, strengthen the tendons, and unblock the collaterals, treating low back pain and rheumatic pain caused by kidney deficiency.

[0026] The prescription contains Angelica dahurica, Prunus mume, and red silk thread: Angelica dahurica is good at dispelling wind and dampness, relieving pain and unblocking meridians, and is especially good at treating rheumatic pain in the lower limbs; Prunus mume clears away heat and detoxifies, promotes blood circulation and disperses blood stasis, and can clear away heat and dampness, promote blood circulation and unblock meridians; red silk thread disperses blood stasis and reduces swelling, clears the liver and reduces turbidity. The three medicines are used together to dispel dampness without damaging yin, warm the body without being dry and strong, soothe the liver and regulate qi, remove dampness and remove blood stasis, and can not only dispel rheumatic arthritis, but also relieve muscle and joint pain. It is suitable for limb discomfort and joint pain caused by dampness, long-term cold, qi stagnation and blood stasis.

[0027] Poria cocos and coix seed in the formula: Poria cocos strengthens the spleen and eliminates dampness, calms the mind and soothes the nerves. It helps transport dampness, resolves phlegm and dampness, and regulates qi and harmonizes the stomach. It not only regulates dampness and phlegm stagnation in the middle burner, but also regulates the smooth flow of qi. It is an important foundation for the entire formula to tonify the kidneys, eliminate dampness, regulate qi and resolve phlegm. Pinellia ternata attacks pathogenic factors, quickly dissolves phlegm and dampness, and relieves acute pain. Poria cocos strengthens the body, strengthening the spleen and stomach and preventing the regeneration of dampness. Coix seed promotes diuresis and eliminates dampness, dissipates numbness and resolves stagnation, and also strengthens the spleen. The two herbs together dispel dampness without damaging yin, and warm and promote circulation without being too dry. They can not only eliminate rheumatic obstruction but also relieve muscle and joint pain. They are suitable for limb weakness and joint pain caused by dampness, long-term cold, qi stagnation, and blood stasis.

[0028] The motherwort in this formula promotes blood circulation, dissipates stasis, promotes diuresis, and reduces swelling. It is particularly effective in dredging blood vessels, regulating menstruation and alleviating pain, while also having the effects of clearing heat and detoxifying. Motherwort enters the liver and heart meridians, harmonizing qi and blood, removing stasis and unblocking the meridians. It is suitable for pain caused by blood stasis and qi stagnation, or for meridian obstruction. When combined with Eucommia ulmoides, it enhances the overall efficacy of promoting blood circulation, removing stasis, regulating menstruation and alleviating pain, and promoting joint function. DETAILED DESCRIPTION

[0029] To better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below with reference to the following examples. In the examples, the experimental methods used are conventional methods unless otherwise specified, and the materials and reagents used are all commercially available unless otherwise specified.

[0030] The ginger juice used in the present invention is obtained by squeezing the juice from fresh zingiber officinale.

[0031] Example 1

[0032] A traditional Chinese medicine composition comprises the following substances in parts by weight: 15 parts of Eucommia ulmoides, 20 parts of Radix Trichosanthis, 20 parts of Cyathulae chinensis, 10 parts of Angelica dahurica, 5 parts of Red Silk Thread, 10 parts of Coix seeds, 15 parts of Rhizoma Cibotii, 20 parts of Poria cocos, and 15 parts of Leonurus japonicus.

[0033] The Chinese medicine composition is prepared into a medicinal cake for external application by the following method: after mixing the above compositions, grinding and sieving (100 mesh) to obtain a powder of the Chinese medicine composition, adding auxiliary materials (the mass ratio of medicinal powder: white vinegar: ginger juice: honey is 2:1:1:0.7) to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

[0034] Example 2

[0035] A traditional Chinese medicine composition comprises the following substances in parts by weight: 10 parts of Eucommia ulmoides, 15 parts of Rhizoma Coptidis, 13 parts of Cyathula capitata, 5 parts of Angelica dahurica, 10 parts of Red Silk Thread, 7 parts of Coix seeds, 12 parts of Rhizoma Cibotii, 6 parts of Poria cocos, and 18 parts of Leonurus japonicus.

[0036] The Chinese medicine composition is prepared into a medicinal cake for external application by the following method: after mixing the above compositions, grinding and sieving (100 mesh) to obtain a powder of the Chinese medicine composition, adding auxiliary materials (the mass ratio of medicinal powder: white vinegar: ginger juice: honey is 2:1:1:0.7) to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

[0037] Example 3

[0038] A traditional Chinese medicine composition comprises the following substances in parts by weight: 13 parts of Eucommia ulmoides, 11 parts of Rhizoma Coptidis, 15 parts of Cyathula capitata, 6 parts of Angelica dahurica, 16 parts of Red Silk Thread, 5 parts of Coix seeds, 16 parts of Rhizoma Cibotii, 8 parts of Poria cocos, and 15 parts of Leonurus japonicus.

[0039] The Chinese medicine composition is prepared into a medicinal cake for external application by the following method: after mixing the above compositions, grinding and sieving (100 mesh) to obtain a powder of the Chinese medicine composition, adding auxiliary materials (the mass ratio of medicinal powder: white vinegar: ginger juice: honey is 2:1:1:0.7) to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

[0040] Example 4

[0041] A traditional Chinese medicine composition comprises the following substances in parts by weight: 18 parts of Eucommia ulmoides, 10 parts of Rhizoma Coptidis, 10 parts of Cyathula capitata, 8 parts of Angelica dahurica, 12 parts of Red Silk Thread, 6 parts of Coix seeds, 10 parts of Rhizoma Cibotii, 10 parts of Poria cocos, and 16 parts of Leonurus japonicus.

[0042] The Chinese medicine composition is prepared into a medicinal cake for external application by the following method: after mixing the above compositions, grinding and sieving (100 mesh) to obtain a powder of the Chinese medicine composition, adding auxiliary materials (the mass ratio of medicinal powder: white vinegar: ginger juice: honey is 2:1:1:0.7) to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

[0043] Example 5

[0044] A traditional Chinese medicine composition comprises the following substances in parts by weight: 20 parts of Eucommia ulmoides, 8 parts of Rhizoma Coptidis, 20 parts of Cyathula capitata, 10 parts of Angelica dahurica, 20 parts of Red Silk Thread, 8 parts of Coix seeds, 20 parts of Rhizoma Cibotii, 5 parts of Poria cocos, and 20 parts of Leonurus japonicus.

[0045] The Chinese medicine composition is prepared into a medicinal cake for external application by the following method: after mixing the above compositions, grinding and sieving (100 mesh) to obtain a powder of the Chinese medicine composition, adding auxiliary materials (the mass ratio of medicinal powder: white vinegar: ginger juice: honey is 2:1:1:0.7) to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

[0046] Test example

[0047] A total of 150 patients with chronic lumbar muscle strain admitted to our hospital between July 2023 and June 2024 were selected as research subjects. Inclusion criteria: patients diagnosed with chronic lumbar muscle strain by physical examination and imaging examination, with normal language function, mental state, and comprehension function, and who signed the informed consent form.

[0048] Inclusion criteria: Voluntary participation and signing of informed consent; no other treatment or use of other drugs within 1 month.

[0049] Exclusion criteria include lumbar disc herniation, lumbar compression fracture, lumbar tuberculosis, ankylosing spondylitis, severe liver and kidney dysfunction, withdrawal from the trial, cardiovascular and cerebrovascular diseases, skin damage, and allergy to study drugs.

[0050] The patients were randomly divided into control group, experimental group 1 and experimental group 2, with 46 cases in each group.

[0051] Patients in the control group received a conventional treatment plan, instructing them to develop healthy living and working habits, avoid prolonged sitting or standing, and adopt correct posture when lifting heavy objects. Within their tolerance, they were advised to engage in appropriate activities and back muscle exercises, or to change their body position to reduce lower back pain. A waist brace was used if necessary. Oral medications such as etoricoxib and celecoxib were administered, with dosages following the instructions.

[0052] Patients in the experimental group 1 were given a conventional treatment plan and told to develop healthy living and working habits, avoid sitting or standing for long periods of time, and adopt the correct posture when lifting heavy objects. Within the body's tolerance range, appropriate activities and back muscle function exercises can be performed, or waist pain can be reduced by changing body position, and a waist protector can be worn if necessary. In terms of medication, the Chinese medicine composition prepared in Example 1 of the present invention was pressed into a cake shape and applied to acupuncture points (select Shenshu point, Dachangshu point, Guanyuan point, Yaoyangguan point, Zhibian point, Yanglingquan point), fixed with a 3M dressing, removed after 4 hours, and 3 days as a course of treatment; 3-5 courses of treatment were applied.

[0053] The patients in the experimental group 2 were given a conventional treatment plan, and were informed to develop healthy living and working habits, avoid sitting or standing for long periods of time, and adopt the correct posture when lifting heavy objects. Within the body's tolerance range, appropriate activities and back muscle function exercises can be performed, or waist pain can be reduced by changing the body position. If necessary, a waist protector can be worn. Medication is given orally, and drugs such as etoricoxib and celecoxib are used. The dosage is based on the drug instructions. At the same time, the Chinese medicine composition prepared by the invention is pressed into a cake shape and applied to acupuncture points (select Shenshu acupoint, Dachangshu acupoint, Guanyuan acupoint, Yaoyangguan acupoint, Zhibian acupoint, Yanglingquan acupoint), fixed with a 3M dressing, removed after 4 hours, and 3 days as a course of treatment; 1-2 courses of treatment are applied.

[0054] There was no statistically significant difference in gender, age, and disease course among the control group, experimental group 1, and experimental group 2 (P>0.05), and they were comparable (see Table 1).

[0055] Table 1

[0056]

[0057] Observation Indicators: Efficacy criteria were established based on the "Standards for Diagnosis and Efficacy of Traditional Chinese Medicine Diseases and Syndromes." Cured: no low back pain symptoms, no restriction of low back movement; effective: significant relief of low back pain, with minimal restriction of low back movement; ineffective: no significant improvement in either low back pain or the degree of restriction of low back movement. Total effective rate = (cure rate + effective rate). The Oswestry Disability Index (ODI) was used as a specific indicator for low back pain evaluation. The total score ranges from 0 to 100, with higher total scores indicating more severe symptoms. ODI scores were recorded before treatment and 10, 20, and 30 days after treatment.

[0058] There was no statistically significant difference in the ODI scores before treatment among the three groups (P>0.05), indicating comparability. After treatment, the ODI scores of all three groups decreased compared to before treatment. After 10, 20, and 30 days of treatment, patients in the control group of this experiment took Western medicine alone as a treatment method, patients in experimental group 1 applied the Chinese medicinal cake of the present invention as a treatment method, and patients in experimental group 2 took Western medicine and applied the Chinese medicinal cake of the present invention as a treatment method.

[0059] Table 2 is a comparison of the ODI scores of patients with lumbar muscle strain before and after treatment. As shown in Table 2, compared with the control group, the ODI scores of patients in the experimental group 1 were lower than those in the control group. It can be clearly seen that the Chinese medicine cake of the present invention is used to treat patients with lumbar muscle strain, and its therapeutic effect is better than that of Western medicine. Moreover, since the Chinese medicine cake of the present invention is an external medicine, it has fewer side effects on the patient's body than Western medicine taken orally. Compared with the experimental group 1, the patients in the experimental group 2 had more significant therapeutic effects (lower ODI scores), indicating that the Chinese medicine cake of the present invention can be used simultaneously with patients taking Western medicine, and the therapeutic effect is more significant than taking Western medicine alone.

[0060] Table 2 Comparison of ODI scores before and after treatment in patients with lumbar muscle strain ( point)

[0061] Group Number of cases Before treatment After 10 days of treatment After 20 days of treatment After 30 days of treatment control group 46 53.0±10.4 33.1±8.9 28.2±10.4 23.8±10.5 Experimental group 1 46 52.6±11.1 31.7±9.3 25.4±10.6 19.7±10.2 Experimental Group 2 46 51.8±10.6 23.9±10.2 14.7±10.1 6.3±10.6

[0062] Table 3 Comparison of clinical treatment effectiveness of patients with lumbar muscle strain (n)

[0063] Group get well Significant effect efficient invalid Total efficiency control group 9 13 21 3 93.48％ Experimental group 1 18 20 6 2 95.65％ Experimental Group 2 22 21 2 1 97.83％

[0064] Table 3 shows a comparison of clinical treatment efficacy rates for patients with lumbar muscle strain. As can be seen from Table 3, the total efficacy rate for the control group was 93.48%, while that for test groups 1 and 2 was 95.65% and 97.83%, respectively. Furthermore, the number of patients who recovered was double that of the control group, demonstrating that the external application of the Chinese medicinal cake of the present invention significantly improves the recovery rate compared to oral administration of Western medicine alone.

[0065] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A Chinese medicine composition, characterized in that The invention comprises the following substances in parts by weight: 10-20 parts of Eucommia ulmoides, 10-15 parts of Rhizoma Coptidis, 10-20 parts of Cyathula capitata, 5-10 parts of Angelica dahurica, 10-20 parts of Red Silk Thread, 5-10 parts of Coix seeds, 10-20 parts of Rhizoma Cibotii, 5-10 parts of Poria cocos and 15-20 parts of Leonurus japonicus.

2. The Chinese medicine composition according to claim 1, characterized in that The above-mentioned traditional Chinese medicine composition is composed of the following substances in parts by weight: 15 parts of Eucommia ulmoides, 20 parts of Tripterygium wilfordii, 10 parts of Angelica dahurica, 15 parts of Prunus mume, 20 parts of Poria cocos, 20 parts of Cyathula capitata, 5 parts of red silk thread, 30 parts of Coix seeds, and 15 parts of Leonurus japonicus.

3. The Chinese medicine composition according to claim 1, characterized in that The above-mentioned Chinese medicine composition also includes auxiliary materials.

4. The Chinese medicine composition according to claim 3, characterized in that The auxiliary materials are ginger juice, white vinegar and honey.

5. Use of the Chinese medicine composition according to any one of claims 1 to 4 in the preparation of a medicament for treating chronic lumbar muscle strain.

6. A method for preparing a traditional Chinese medicine cake for treating chronic lumbar muscle strain, characterized in that: The preparation method comprises mixing the components of the Chinese medicine composition according to any one of claims 1 to 4, grinding and sieving to obtain powder of the Chinese medicine composition, adding auxiliary materials to the powder of the Chinese medicine composition, blending evenly, and pressing into a cake shape.

7. The method for preparing the Chinese medicinal cake for treating chronic lumbar muscle strain according to claim 6, characterized in that: After grinding, the powder is sieved through 80-120 mesh.

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