Moisturizing and oil-controlling composition and application thereof

Abstract

The invention relates to a moisturizing and oil-controlling composition and application thereof. The moisturizing and oil control composition is prepared from sodium pyrrolidone carboxylate, recombinant XVII type collagen and a plant extract. According to the composition, the synergistic effect of the sodium pyrrolidone carboxylate and the recombinant XVII type collagen in the moisturizing and relieving aspects is utilized, so that the composition can help oily skin keep healthy water-oil balance while playing a moisturizing effect, and the oil control effect is improved. Besides, the plant extract is added into the composition, so that water-oil balance of the skin can be further adjusted, and the sodium pyrrolidone carboxylate and the recombinant XVII type collagen are promoted to play the effects of relieving, moisturizing and controlling oil.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and in particular relates to a moisturizing and oil-controlling composition and application thereof. Background Art

[0002] With the development of society and advancements in technology, people's demand for cosmetics is constantly increasing. Oil-control and moisturizing products, in particular, are favored by consumers because they can effectively regulate skin oil secretion and keep the skin fresh and comfortable. At the same time, plant extracts are increasingly used in cosmetics because they are natural, safe, and effective.

[0003] CN117338612A discloses a moisturizing shower gel with a low fatty acid content and a preparation method thereof. The moisturizing shower gel comprises, by weight, 80-97% of a cleaning base, 0.01-3% of a thickener, 0.01-2% of a fatty acid emollient, 0.5-8% of a fatty acid amidopropyl betaine, and 0.01-1.0% of a neutralizer. The moisturizing shower gel is primarily formulated with a surfactant and a small amount of fatty acid to produce a moisturizing shower gel with a low saponification degree and good stability. The gel has the advantages of rapid foaming, rich lather, and leaves the skin feeling smooth and moisturized after washing, avoiding the feeling of false slipperiness experienced with conventional shower gels and the dryness experienced with soap-based shower gels.

[0004] Existing oil-control and moisturizing products primarily achieve their effectiveness by adding chemically synthesized ingredients, such as dimethicone, zinc oxide, and alcohol. While these ingredients can quickly absorb excess oil, long-term use can cause skin irritation and fail to fundamentally address the problem of excessive oil secretion. Additionally, some products use moisturizers to retain skin moisture, but these moisturizers are often ineffective and fail to meet consumer demand.

[0005] Therefore, how to develop a shower gel product that has the effects of moisturizing, soothing and oil control has become one of the technical problems that need to be solved urgently. Summary of the Invention

[0006] In view of the shortcomings of the prior art, the present invention aims to provide a moisturizing and oil-controlling composition and its application. The moisturizing and oil-controlling composition has excellent moisturizing, soothing and oil-controlling effects, can significantly increase the moisture content of the skin, and regulate the water-oil balance of the skin.

[0007] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:

[0008] In a first aspect, the present invention provides a moisturizing and oil-controlling composition, comprising sodium pyrrolidonecarboxylate, recombinant type XVII collagen, and a plant extract.

[0009] Sodium pyrrolidonecarboxylate is a natural component of the skin that strengthens keratin and enhances the skin's inherent moisturizing capacity. It acts as a barrier to control epidermal water loss and has a very strong moisturizing effect. Recombinant type XVII collagen is a key factor in regulating various stem cells and has excellent anti-aging and moisturizing effects.

[0010] The present invention creatively discovered that sodium pyrrolidone carboxylate and recombinant type XVII collagen have significant synergistic effects in moisturizing and soothing. At the same time, they can help oily skin maintain a healthy water-oil balance, helping to prevent problems such as clogged pores and acne caused by excessive oil production.

[0011] In addition, adding plant extracts to the composition can further regulate the water and oil balance of the skin and promote sodium pyrrolidone carboxylate and recombinant type XVII collagen to exert soothing, moisturizing and oil-control effects.

[0012] Preferably, the moisturizing and oil-controlling composition comprises, by weight, 5-10 parts of sodium pyrrolidonecarboxylate, 1-7 parts of recombinant type XVII collagen, and 0.1-1 part of a plant extract.

[0013] Among them, the specific point values ​​in 5-10 parts can be selected from 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, etc., the specific point values ​​in 1-7 parts can be selected from 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, etc., and the specific point values ​​in 0.1-1 parts can be selected from 0.1 parts, 0.3 parts, 0.5 parts, 0.7 parts, 0.9 parts, 1 part, etc.

[0014] Preferably, the plant extracts include gentiana flower extract, juglans regia seed oil and moringa seed oil.

[0015] Gentiana scabra, a traditional herbal medicine with heat-clearing and analgesic properties, primarily contains iridoid glycosides such as gentiopicroside, swetimarin, swetirin, and loganinic acid. It also contains flavonoids, phenylpropanoids, alkaloids, phenylethanoid glycosides, benzophenones, and anthraquinones, offering soothing and restorative properties. Juglans regia seed oil, a plant oil extracted from the kernel of the juglans regia plant, is rich in unsaturated fatty acids, vitamin E, polyphenols, and other active ingredients, boasting moisturizing and restorative properties. Moringa seeds, derived from the seeds of the Moringa oleifera tree, are known to soothe, soften, moisturize, and cleanse the skin.

[0016] The present invention innovatively discovered that gentiana flower extract, walnut seed oil, and moringa seed oil exhibit significant synergistic effects in moisturizing and oil-controlling. The three ingredients work together to enhance the skin's water-oil balance, promoting the effects of sodium pyrrolidonecarboxylate and recombinant type XVII collagen, and enhancing the moisturizing and oil-control properties of the composition.

[0017] Preferably, the mass ratio of the gentian flower extract, walnut seed oil and moringa seed oil is 1:(0.5-3):(1-5).

[0018] Among them, the specific point values ​​in 0.5-3 can be selected from 0.5, 1, 1.5, 2, 2.5, 3, etc., and the specific point values ​​in 1-5 can be selected from 1, 2, 3, 4, 5, etc.

[0019] Preferably, the gentiana flower extract is prepared by a preparation method comprising the following steps:

[0020] (1) mixing the gentian flower raw material with water and performing microfluidization extraction to obtain a gentian flower crude extract;

[0021] (2) Purify the crude extract of gentiana flower using macroporous resin, and elute it with water and ethanol aqueous solution in sequence, collect the ethanol aqueous solution fraction, and dry it to obtain the gentiana flower extract.

[0022] The invention performs microfluidization extraction on the gentian flower raw material, thereby fully extracting the effective components in the gentian flower and improving the moisturizing, soothing and oil-control effects of the prepared gentian flower extract.

[0023] Preferably, the material-liquid ratio of the gentian flower raw material to water in step (1) is 1:(30-70) g / mL, for example, it can be 1:30 g / mL, 1:40 g / mL, 1:50 g / mL, 1:60 g / mL, 1:70 g / mL, etc.

[0024] Preferably, the temperature of the microfluidic extraction in step (1) is 40-80° C., and the pressure of the microfluidic extraction is 100-250 MPa.

[0025] Preferably, the number of microfluidic extractions in step (1) is 1-4 times.

[0026] Among them, the specific point values ​​in 40-80℃ can be selected from 40℃, 50℃, 60℃, 70℃, 80℃, etc., the specific point values ​​in 100-250Mpa can be selected from 100Mpa, 150Mpa, 200Mpa, 250Mpa, etc., and the specific point values ​​in 1-4 times can be selected from 1 time, 2 times, 3 times, 4 times.

[0027] Preferably, the types of the macroporous resin in step (2) include DAX-8 and / or CAD-40, preferably DAX-8 and CAD-40.

[0028] DAX-8 macroporous resin is a medium-polar macroporous adsorption resin, which is polymerized from methacrylic acid and has a large surface area and continuous pore size. CAD-40 macroporous resin is a macroporous neutral resin with a high surface area, high pore volume and a large pore size.

[0029] The present invention creatively discovered that by co-doping DAX-8 macroporous resin and CAD-40 macroporous resin, the oil-controlling effective components can be fully separated, thereby improving the moisturizing and oil-control effects of the gentian flower extract.

[0030] Preferably, the mass ratio of the DAX-8 macroporous resin to the CAD-40 macroporous resin is 1:(1-3), for example, 1:1, 1:1.5, 1:2, 1:2.5, 1:3, etc.

[0031] Preferably, the volume percentage of ethanol in the ethanol aqueous solution in step (2) is 80-98%, for example, it can be 80%, 85%, 90%, 95%, 98%, etc.

[0032] Preferably, the flow rates of the water and ethanol aqueous solutions for elution in step (2) are independently 0.5-2 BV / h, and the amounts used are independently 1-5 BV.

[0033] Among them, the specific point values ​​in 0.5-2BV / h can be selected from 0.5BV / h, 1BV / h, 1.5BV / h, 2BV / h, etc., and the specific point values ​​in 1-5BV can be selected from 1BV, 2BV, 3BV, 4BV, 5BV, etc.

[0034] Preferably, the walnut seed oil is prepared by a preparation method comprising the following steps:

[0035] (I) mixing a raw material of walnut kernel with an aqueous solution of a complex enzyme to perform an enzymatic hydrolysis reaction, and drying to obtain an enzymatic hydrolysis product;

[0036] (II) The enzymatic hydrolysis product is subjected to supercritical CO2 extraction to obtain walnut seed oil.

[0037] The present invention prepares walnut seed oil by combining raw material enzymatic hydrolysis with supercritical CO2 extraction. The prepared walnut seed oil has excellent moisturizing and oil-control effects.

[0038] Preferably, the material-liquid ratio of the walnut kernel raw material to the aqueous solution of the complex enzyme in step (I) is 1:(20-40) g / mL, for example, it can be 1:20 g / mL, 1:25 g / mL, 1:30 g / mL, 1:35 g / mL, 1:40 g / mL, etc.

[0039] Preferably, in the aqueous solution of the complex enzyme in step (I), the mass percentage of the complex enzyme is 0.1-1%, for example, it can be 0.1%, 0.3%, 0.5%, 0.7%, 0.9%, 1%, etc.

[0040] Preferably, the complex enzyme comprises cellulase, pectinase and xylanase.

[0041] Cellulase can degrade cellulose to produce cellobiose and glucose; pectinase can act on the glycosidic bonds between D-galacturonic acid residues in pectin to break the pectin molecules; xylanase can hydrolyze xylan in hemicellulose and further destroy the cell wall network.

[0042] In the present invention, cellulase, pectinase and xylanase are used to synergistically hydrolyze the walnut kernels, which can further promote the prepared walnut seed oil to exert oil-controlling and moisturizing effects.

[0043] Preferably, the mass ratio of the cellulase, pectinase and xylanase is (3-8):(0.5-2):(1-5).

[0044] Among them, the specific point values ​​in 3-8 can be selected from 3, 4, 5, 6, 7, 8, etc., the specific point values ​​in 0.5-2 can be selected from 0.5, 1, 1.5, 2, etc., and the specific point values ​​in 1-5 can be selected from 1, 2, 3, 4, 5, etc.

[0045] Preferably, the temperature of the enzymatic hydrolysis reaction in step (I) is 40-60° C., and the time of the enzymatic hydrolysis reaction is 0.2-1 h.

[0046] Among them, the specific point values ​​in 40-60℃ can be selected from 40℃, 45℃, 50℃, 55℃, 60℃, etc., and the specific point values ​​in 0.2-1h can be selected from 0.2h, 0.4h, 0.6h, 0.8h, 1h, etc.

[0047] Preferably, the temperature of the supercritical CO2 extraction in step (II) is 40-60°C, the pressure of the supercritical CO2 extraction is 30-50MPa, the time of the supercritical CO2 extraction is 0.5-2h, and the CO2 flow rate of the supercritical CO2 extraction is 10-40L / h.

[0048] Among them, the specific point values ​​in 40-60℃ can be selected from 40℃, 45℃, 50℃, 55℃, 60℃, etc., the specific point values ​​in 30-50MPa can be selected from 30MPa, 35MPa, 40MPa, 45MPa, 50MPa, etc., the specific point values ​​in 0.5-2h can be selected from 0.5h, 1h, 1.5h, 2h, etc., and the specific point values ​​in 10-40L / h can be selected from 10L / h, 20L / h, 30L / h, 40L / h, etc.

[0049] Preferably, the Moringa seed oil is prepared by a preparation method comprising the following steps:

[0050] The moringa seed raw material is mixed with petroleum ether and subjected to hot reflux extraction to obtain moringa seed oil.

[0051] The moringa seed oil obtained by the present invention through hot reflux extraction by mixing the moringa seed raw material with petroleum ether can further exert a synergistic relationship with the gall flower extract and the walnut seed oil to provide the overall moisturizing and oil-control effects of the composition.

[0052] Preferably, the material-liquid ratio of the Moringa seed raw material to petroleum ether is 1:(3-10) g / mL, for example, it can be 1:3 g / mL, 1:5 g / mL, 1:7 g / mL, 1:9 g / mL, 1:10 g / mL, etc.

[0053] Preferably, the number of hot reflux extractions is 1-4 times, and the time for each hot reflux extraction is 2-6 hours.

[0054] Among them, the specific point values ​​in 1-4 times can be selected as 1 time, 2 times, 3 times, 4 times, and the specific point values ​​in 2-6h can be selected as 2h, 3h, 4h, 5h, 6h, etc.

[0055] In a second aspect, the present invention provides a moisturizing and oil-controlling shower gel, comprising the moisturizing and oil-controlling composition of the first aspect, a surfactant, a chelating agent, a skin conditioner, and a solvent.

[0056] Preferably, the surfactant includes any one of sodium laureth sulfate, sodium lauryl sulfate, sodium sulfate or lauryl alcohol, or a combination of at least two thereof.

[0057] Preferably, the chelating agent comprises disodium EDTA.

[0058] Preferably, the skin conditioning agent comprises any one of niacinamide, sodium polyaspartate or butylene glycol, or a combination of at least two thereof.

[0059] Preferably, the solvent comprises water.

[0060] Preferably, the moisturizing and oil-controlling shower gel comprises, by mass, 1-5 parts of the moisturizing and oil-controlling composition of the first aspect, 10-30 parts of a surfactant, 0.05-0.1 parts of a chelating agent, 5-10 parts of a skin conditioner, and 55-85 parts of a solvent.

[0061] Among them, the specific point values ​​in 1-5 parts can be selected from 1 part, 2 parts, 3 parts, 4 parts, 5 parts, etc., the specific point values ​​in 10-30 parts can be selected from 10 parts, 15 parts, 20 parts, 25 parts, 30 parts, etc., the specific point values ​​in 0.05-0.1 parts can be selected from 0.05 parts, 0.06 parts, 0.07 parts, 0.08 parts, 0.09 parts, 0.1 parts, etc., the specific point values ​​in 5-10 parts can be selected from 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, etc., and the specific point values ​​in 55-85 parts can be selected from 55 parts, 65 parts, 75 parts, 85 parts, etc.

[0062] In a third aspect, the present invention provides a method for preparing the moisturizing and oil-controlling shower gel according to the second aspect, the preparation method comprising the following steps:

[0063] The solvent, the surfactant and the chelating agent are mixed and homogenized to obtain a mixed liquid; the mixed liquid is mixed and stirred with the moisturizing oil-controlling composition and the skin conditioner to obtain the moisturizing oil-controlling shower gel.

[0064] Preferably, the speed of the mixing and homogenizing before obtaining the mixed liquid is 1000-3000 rpm, the temperature of the mixing and homogenizing is 80-90° C., and the time of the mixing and homogenizing is 10-40 min.

[0065] Preferably, the mixing and stirring speed before obtaining the moisturizing and oil-controlling shower gel is 10-40 rpm, the mixing and stirring temperature is 42-45° C., and the mixing and stirring time is 10-40 min.

[0066] Among them, the specific point values ​​in 1000-3000rpm can be selected from 1000rpm, 1500rpm, 2000rpm, 2500rpm, 3000rpm, etc., the specific point values ​​in 10-40rpm can be selected from 10rpm, 20rpm, 30rpm, 40rpm, etc., the specific point values ​​in 80-90℃ can be selected from 80℃, 82℃, 84℃, 86℃, 88℃, 90℃, etc., the specific point values ​​in 42-45℃ can be selected from 42℃, 43℃, 44℃, 45℃, etc., and the specific point values ​​in 10-40min can be selected from 10min, 20min, 30min, 40min, etc.

[0067] The numerical range described in the present invention includes not only the point values ​​listed above, but also any point values ​​between the above numerical ranges that are not listed. Due to space limitations and for the sake of simplicity, the present invention no longer exhaustively lists the specific point values ​​included in the range.

[0068] Compared with the prior art, the present invention has the following beneficial effects:

[0069] This invention utilizes the synergistic moisturizing and soothing effects of sodium pyrrolidonecarboxylate and recombinant type XVII collagen. This composition not only moisturizes but also helps oily skin maintain a healthy water-oil balance, enhancing oil control. Furthermore, the addition of plant extracts to the composition can further regulate the skin's water-oil balance, promoting the soothing, moisturizing, and oil-control effects of sodium pyrrolidonecarboxylate and recombinant type XVII collagen.

[0070] Furthermore, the plant extracts are a combination of gentian flower extract, walnut seed oil and moringa seed oil. The three cooperate with each other and synergistically enhance their effectiveness, which can better regulate the water and oil balance of the skin, promote the role of sodium pyrrolidonecarboxylate and recombinant type XVII collagen, and enhance the moisturizing and oil-control effects of the composition.

[0071] Furthermore, microfluidization extraction of the gentian flower raw material can fully extract the active ingredients in the gentian flower, improving the moisturizing, soothing, and oil-control effects of the prepared gentian flower extract. Furthermore, co-doping of the crude gentian flower extract with a DAX-8 macroporous resin and a CAD-40 macroporous resin can fully separate and obtain the oil-control active ingredients, thereby improving the moisturizing and oil-control effects of the gentian flower extract.

[0072] Furthermore, the present invention combines enzymatic hydrolysis of raw materials with supercritical CO2 extraction to produce walnut seed oil, resulting in excellent moisturizing and oil-controlling properties. Furthermore, the synergistic enzymatic hydrolysis of walnut kernels using cellulase, pectinase, and xylanase further enhances the oil-controlling and moisturizing properties of the resulting walnut seed oil. DETAILED DESCRIPTION

[0073] In order to further illustrate the technical means and effects adopted by the present invention, the technical solutions of the present invention are further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

[0074] The sources of the components / raw materials in the following embodiments are shown in Table 1.

[0075] Table 1

[0076]

[0077] Preparation Example 1-1

[0078] This preparation example provides a gentiana flower extract, which is prepared by the following method:

[0079] (1) After crushing the gentian flower, the mixture was mixed with water at a solid-liquid ratio of 1:50 g / mL, and subjected to microfluidic extraction (microfluidic extraction temperature was 60° C., pressure was 200 MPa, and was performed twice) to obtain a crude gentian flower extract;

[0080] (2) The crude extract of gentiana flower was loaded onto a macroporous resin (DAX-8 macroporous resin and CAD-40 macroporous resin co-doped in a mass ratio of 1:2) for separation and elution. The separation and elution steps were as follows: elution with water for 2 BV (flow rate of 1 BV / h), and elution with an aqueous solution of 90% ethanol by volume for 2 BV (flow rate of 1 BV / h); the aqueous solution fraction of ethanol was collected and dried to obtain the gentiana flower extract.

[0081] Preparation Example 1-2

[0082] This preparation example provides a gentiana flower extract, which is prepared by the following method:

[0083] (1) After crushing the gentian flower, the mixture was mixed with water at a solid-liquid ratio of 1:30 g / mL, and subjected to microfluidic extraction (microfluidic extraction temperature was 80° C., pressure was 100 MPa, and was performed 4 times) to obtain a crude gentian flower extract;

[0084] (2) The crude extract of gentiana flower was loaded onto a macroporous resin (DAX-8 macroporous resin and CAD-40 macroporous resin co-doped in a mass ratio of 1:3) for separation and elution. The separation and elution steps were as follows: elution with water for 5 BV (flow rate of 2 BV / h), and elution with an aqueous solution of 98% ethanol by volume for 5 BV (flow rate of 2 BV / h); the aqueous solution fraction of ethanol was collected and dried to obtain the gentiana flower extract.

[0085] Preparation Examples 1-3

[0086] This preparation example provides a gentiana flower extract, which is prepared by the following method:

[0087] (1) After crushing the gentian flower, the mixture was mixed with water at a solid-liquid ratio of 1:70 g / mL, and subjected to microfluidic extraction (microfluidic extraction temperature was 40° C., pressure was 250 MPa, and was performed once) to obtain a crude gentian flower extract;

[0088] (2) The crude extract of gentiana flower was loaded onto a macroporous resin (DAX-8 macroporous resin and CAD-40 macroporous resin co-doped in a mass ratio of 1:1) for separation and elution. The separation and elution steps were as follows: 1 BV of water elution (flow rate of 0.5 BV / h), 1 BV of elution with an aqueous solution of 80% ethanol by volume (flow rate of 0.5 BV / h); the aqueous ethanol fraction was collected and dried to obtain the gentiana flower extract.

[0089] Preparation Examples 1-4

[0090] This preparation example provides a gentian flower extract, which differs from Preparation Example 1-1 only in that the microfluidic extraction in step (1) is adjusted to ultrasonic extraction (the ultrasonic extraction temperature is 60°C, the power is 300W, and the time is 30min), and the remaining steps are consistent with Preparation Example 1-1.

[0091] Preparation Examples 1-5

[0092] This preparation example provides a gentian flower extract, which differs from Preparation Example 1-1 only in that the macroporous resin in step (2) is adjusted to a single DAX-8 type macroporous resin, and the remaining steps are consistent with Preparation Example 1-1.

[0093] Preparation Examples 1-6

[0094] This preparation example provides a gentian flower extract, which differs from Preparation Example 1-1 only in that the macroporous resin in step (2) is adjusted to a single CAD-40 type macroporous resin, and the remaining steps are consistent with Preparation Example 1-1.

[0095] Preparation Example 2-1

[0096] This preparation example provides a walnut seed oil, which is prepared by the following method:

[0097] (1) After the walnut kernels are crushed, they are mixed with an aqueous solution of a complex enzyme (the mass percentage of the complex enzyme in the aqueous solution is 0.5%, and the complex enzyme is cellulase, pectinase and xylanase in a mass ratio of 5:1:3) at a solid-liquid ratio of 1:30 g / mL, and enzymolysis is carried out at 50°C for 0.5 h, and then the temperature is raised to 90°C and maintained for 10 min to inactivate the enzyme; after the enzyme is inactivated, hot air drying is carried out at 50°C to obtain an enzymolysis product;

[0098] (2) The enzymatic hydrolysis product was subjected to supercritical CO2 extraction (temperature of 50°C, pressure of 40 MPa, time of 1 h, CO2 flow rate of 20 L / h) to obtain walnut seed oil.

[0099] Preparation Example 2-2

[0100] This preparation example provides a walnut seed oil, which is prepared by the following method:

[0101] (1) After the walnut kernels are crushed, they are mixed with an aqueous solution of a complex enzyme (the mass percentage of the complex enzyme in the aqueous solution is 0.1%, and the complex enzyme is cellulase, pectinase and xylanase in a mass ratio of 3:2:1) at a material-liquid ratio of 1:40 g / mL, and enzymatically hydrolyzed at 40°C for 1 hour, and then heated to 90°C and maintained for 10 minutes to inactivate the enzyme; after the enzyme is inactivated, hot air drying is performed at 50°C to obtain an enzymatic hydrolysis product;

[0102] (2) The enzymatic hydrolysis product was subjected to supercritical CO2 extraction (temperature of 40°C, pressure of 50 MPa, time of 0.5 h, CO2 flow rate of 10 L / h) to obtain walnut seed oil.

[0103] Preparation Example 2-3

[0104] This preparation example provides a walnut seed oil, which is prepared by the following method:

[0105] (1) After the walnut kernels are crushed, they are mixed with an aqueous solution of a complex enzyme (the mass percentage of the complex enzyme in the aqueous solution is 1%, and the complex enzyme is cellulase, pectinase and xylanase in a mass ratio of 8:0.5:5) at a material-liquid ratio of 1:20 g / mL, and enzymolysis is carried out at 60°C for 0.2 h, and then the temperature is raised to 90°C and maintained for 10 min to inactivate the enzyme; after the enzyme is inactivated, hot air drying is carried out at 50°C to obtain an enzymolysis product;

[0106] (2) The enzymatic hydrolysis product was subjected to supercritical CO2 extraction (temperature of 60°C, pressure of 30 MPa, time of 2 h, CO2 flow rate of 40 L / h) to obtain walnut seed oil.

[0107] Preparation Example 2-4

[0108] This preparation example provides a walnut seed oil, which differs from Preparation Example 2-1 only in that the total mass of the complex enzyme is kept unchanged and the complex enzyme is replaced by cellulase and pectinase in a mass ratio of 5:1.

[0109] Preparation Example 2-5

[0110] This preparation example provides a walnut seed oil, which differs from Preparation Example 2-1 only in that the total mass of the complex enzyme is kept unchanged and the complex enzyme is replaced with cellulase and xylanase in a mass ratio of 5:3.

[0111] Preparation Example 2-6

[0112] This preparation example provides a walnut seed oil, which differs from Preparation Example 2-1 only in that the total mass of the complex enzyme is kept unchanged and the complex enzyme is replaced with pectinase and xylanase in a mass ratio of 1:3.

[0113] Preparation Example 3-1

[0114] This preparation example provides a Moringa seed oil, which is prepared by the following method:

[0115] The Moringa seed kernels were crushed and then mixed with petroleum ether at a solid-liquid ratio of 1:5 g / mL. Hot reflux extraction was performed three times, each time for 4 hours. The extracts were combined, filtered, and dried in a vacuum drying oven at 60°C and 0.1 MPa to obtain Moringa seed oil.

[0116] Preparation Example 3-2

[0117] This preparation example provides a Moringa seed oil, which is prepared by the following method:

[0118] The Moringa seed kernels were crushed and then mixed with petroleum ether at a solid-liquid ratio of 1:3 g / mL. Hot reflux extraction was performed once for 6 hours. The extract was filtered and dried in a vacuum drying oven at 50°C and 0.15 MPa to obtain Moringa seed oil.

[0119] Preparation Example 3-3

[0120] This preparation example provides a Moringa seed oil, which is prepared by the following method:

[0121] The Moringa seed kernels were crushed and then mixed with petroleum ether at a solid-liquid ratio of 1:10 g / mL. Hot reflux extraction was performed 4 times, each time for 2 h. The extract was filtered and dried in a vacuum drying oven at 80°C and 0.05 MPa to obtain Moringa seed oil.

[0122] Example 1

[0123] This embodiment provides a moisturizing and oil-control composition, which includes, by mass, 7 parts of sodium pyrrolidone carboxylate, 4 parts of recombinant type XVII collagen, and 0.5 parts of a plant extract (the gentian flower extract obtained in Preparation Example 1-1, the walnut seed oil obtained in Preparation Example 2-1, and the moringa seed oil obtained in Preparation Example 3-1 are in a mass ratio of 1:2:3).

[0124] Example 2

[0125] This embodiment provides a moisturizing and oil-control composition, which includes, by mass, 5 parts of sodium pyrrolidone carboxylate, 7 parts of recombinant type XVII collagen, and 1 part of a plant extract (the gentian flower extract obtained in Preparation Example 1-2, the walnut seed oil obtained in Preparation Example 2-2, and the moringa seed oil obtained in Preparation Example 3-2 are in a mass ratio of 1:3:1).

[0126] Example 3

[0127] This embodiment provides a moisturizing and oil-control composition, which includes, by mass, 10 parts of sodium pyrrolidonecarboxylate, 1 part of recombinant type XVII collagen, and 0.1 part of a plant extract (the gentian flower extract obtained in Preparation Example 1-3, the walnut seed oil obtained in Preparation Example 2-3, and the moringa seed oil obtained in Preparation Example 3-3 are in a mass ratio of 1:0.5:5).

[0128] Examples 4-6

[0129] Examples 4-6 each provide a moisturizing and oil-controlling composition, which differs from Example 1 only in that the gentian flower extract obtained in Preparation Example 1-1 is replaced with equal amounts of gentian flower extracts obtained in Preparation Examples 1-4 to 1-6, respectively, and the rest of the formula remains consistent with Example 1.

[0130] Examples 7-9

[0131] Examples 7-9 each provide a moisturizing and oil-controlling composition, which differs from Example 1 only in that the walnut seed oil obtained in Preparation Example 2-1 is replaced with equal amounts of walnut seed oil obtained in Preparation Examples 2-4 to 2-6, respectively, and the rest of the formula remains consistent with Example 1.

[0132] Example 10

[0133] This embodiment provides a moisturizing and oil-controlling composition, which differs from Example 1 only in that the total mass of the plant extract is kept unchanged, and the plant extract is replaced with gentian flower extract and walnut seed oil in a mass ratio of 1:2. The rest of the formula remains the same as in Example 1.

[0134] Example 11

[0135] This embodiment provides a moisturizing and oil-controlling composition, which differs from Example 1 only in that the total mass of the plant extract is kept unchanged, and the plant extract is replaced with gentian flower extract and moringa seed oil in a mass ratio of 1:3. The rest of the formula remains the same as in Example 1.

[0136] Example 12

[0137] This embodiment provides a moisturizing and oil-controlling composition, which differs from Example 1 only in that the total mass of the plant extract is kept unchanged, and the plant extract is replaced with walnut seed oil and moringa seed oil in a mass ratio of 2:3. The rest of the formula remains the same as in Example 1.

[0138] Comparative Example 1

[0139] This comparative example provides a composition, which differs from Example 1 only in that the plant extract is removed and the reduced mass fraction is supplemented by sodium pyrrolidonecarboxylate and recombinant type XVII collagen in a mass ratio of 7:4.

[0140] Comparative Example 2

[0141] This comparative example provides a composition, which differs from Example 1 only in that sodium pyrrolidonecarboxylate is removed and recombinant type XVII collagen is replaced with 11 parts, and the rest of the formula remains consistent with Example 1.

[0142] Comparative Example 3

[0143] This comparative example provides a composition, which differs from Example 1 only in that the recombinant type XVII collagen is removed and sodium pyrrolidonecarboxylate is replaced with 11 parts, and the rest of the formula remains the same as that of Example 1.

[0144] Application Example 1

[0145] This application example provides a moisturizing and oil-controlling shower gel, which includes 5 parts of the moisturizing and oil-controlling composition of Example 1, 20 parts of a surfactant (sodium laureth sulfate, sodium lauryl sulfate, sodium sulfate and lauryl alcohol in a mass ratio of 9:3:0.5:0.2), 0.1 parts of a chelating agent (disodium ethylenediaminetetraacetic acid), 5 parts of a skin regulator (niacinamide, sodium polyaspartate and butylene glycol in a mass ratio of 1:0.5:0.1), and the balance is water.

[0146] The preparation process is:

[0147] The solvent, surfactant and chelating agent were mixed and homogenized at 85° C. and 2000 rpm for 20 minutes, then cooled to 43° C., mixed with the moisturizing oil-control composition and the skin conditioner, and stirred at 20 rpm for 20 minutes to obtain a moisturizing oil-control shower gel.

[0148] Application Example 2

[0149] This application example provides a moisturizing and oil-controlling shower gel, which includes 3 parts of the moisturizing and oil-controlling composition of Example 2, 30 parts of a surfactant (sodium laureth sulfate, sodium lauryl sulfate, sodium sulfate and lauryl alcohol in a mass ratio of 10:4:0.6:0.3), 0.05 parts of a chelating agent (disodium ethylenediaminetetraacetic acid), 8 parts of a skin regulator (niacinamide, sodium polyaspartate and butylene glycol in a mass ratio of 1:0.3:0.3), and the balance is water.

[0150] The preparation process is:

[0151] The solvent, surfactant and chelating agent were mixed and homogenized at 80° C. and 1000 rpm for 40 minutes, then cooled to 42° C., mixed with the moisturizing oil-control composition and the skin conditioner, and stirred at 40 rpm for 10 minutes to obtain a moisturizing oil-control shower gel.

[0152] Application Example 3

[0153] This application example provides a moisturizing and oil-controlling shower gel, which includes 1 part of the moisturizing and oil-controlling composition of Example 3, 10 parts of a surfactant (sodium laureth sulfate, sodium lauryl sulfate, sodium sulfate and lauryl alcohol in a mass ratio of 8:5:0.3:0.2), 0.07 parts of a chelating agent (disodium ethylenediaminetetraacetic acid), 10 parts of a skin regulator (niacinamide, sodium polyaspartate and butylene glycol in a mass ratio of 1:0.1:0.4), and the balance is water.

[0154] The preparation process is:

[0155] The solvent, surfactant and chelating agent were mixed and homogenized at 90° C. and 3000 rpm for 10 minutes, then cooled to 45° C., mixed with the moisturizing oil-control composition and the skin conditioner, and stirred at 10 rpm for 40 minutes to obtain a moisturizing oil-control shower gel.

[0156] Application Example 4-12

[0157] Application Examples 4-12 each provide a moisturizing and oil-controlling shower gel, which differs from Application Example 1 only in that the moisturizing and oil-controlling composition of Example 1 is replaced with moisturizing and oil-controlling compositions of Examples 4-12 of equal mass, respectively, and the remaining formulas and process parameters remain consistent with Application Example 1.

[0158] Comparative Application Examples 1-3

[0159] Comparative Application Examples 1-3 each provide a shower gel, which differs from Application Example 1 only in that the moisturizing and oil-control composition of Example 1 is replaced with the compositions of Comparative Examples 1-3 of equal mass, respectively, and the remaining formulas and process parameters remain consistent with Application Example 1.

[0160] Test Example 1

[0161] Moisturizing effect evaluation:

[0162] 150 volunteers aged between 18 and 60, half male and half female, were selected and divided into 15 groups, with 10 people in each group. Each group used the shower gel of Application Examples 1-12 and Comparative Application Examples 1-3. The usage method was as follows: mark a 4×5cm square on the arm. 2 Wet your arm with clean water as the test area. Then apply 0.04g of body wash to the test area and gently massage for 2 minutes. Rinse thoroughly with clean water and pat dry. Before the test and 15 minutes after rinsing with body wash, measure the moisture content of the stratum corneum using a Corneometer CM825 skin moisture meter and calculate the moisture content growth rate.

[0163] Skin stratum corneum water content growth rate = (D1-D0) / D0×100%;

[0164] Wherein, D1 is the water content of the stratum corneum of the skin after rinsing with shower gel, and D0 is the water content of the stratum corneum of the skin before the start of the test.

[0165] The moisturizing effect test results of the shower gels obtained in each application example and comparative application example are shown in Table 2.

[0166] Table 2

[0167]

[0168]

[0169] Test Example 2

[0170] Soothing effect evaluation:

[0171] The same group of 150 volunteers as in Test Example 1 were selected and divided into 15 groups, with 10 people in each group. Each group used the shower gels of Application Examples 1-12 and Comparative Application Examples 1-3, once a day. No other soothing products were used during the test. Before use and 28 days after use, the water loss at the same part of the inner left arm was measured using a water loss test probe Tewameter TM300, and the transepidermal water loss (TEWL) (g / h / m 2 ), and the reduction rate of transepidermal water loss was calculated.

[0172] Transepidermal water loss reduction rate = (T0-T 28 ) / T0×100%;

[0173] Among them, T 28 It is the transepidermal water loss after using the product for 28 days, and T0 is the transepidermal water loss before use.

[0174] The soothing effect test results of the shower gels obtained in each application example and comparative application example are shown in Table 3.

[0175] Table 3

[0176] sample Transepidermal water loss reduction rate Application Example 1 20.8％ Application Example 2 18.6％ Application Example 3 17.4％ Application Example 4 15.6％ Application Example 5 14.7％ Application Example 6 17.8％ Application Example 7 16.3％ Application Example 8 15.4％ Application Example 9 14.5％ Application Example 10 13.5％ Application Example 11 14.2％ Application Example 12 12.7％ Comparative Application Example 1 12.1％ Comparative Application Example 2 10.6％ Comparative Application Example 3 11.4％

[0177] It can be seen from the test data in Table 2 and Table 3 that the shower gel of the present invention has excellent moisturizing effect.

[0178] Comparison of the data from Application Example 1 and Comparative Application Example 1 shows that the addition of plant extracts can further promote the effects of sodium pyrrolidonecarboxylate and recombinant type XVII collagen, significantly enhancing the moisturizing and soothing efficacy of the composition. Comparison of the data from Application Example 1 and Comparative Application Examples 2-3 shows that sodium pyrrolidonecarboxylate and recombinant type XVII collagen have significant synergistic effects in moisturizing and soothing.

[0179] From the comparison of the data of Application Example 1 and Application Example 4, it can be seen that the microfluidic extraction method can fully extract the effective ingredients in the gentian flower, thereby improving the moisturizing and soothing effect of the prepared gentian flower extract.

[0180] From the comparison of the data of Application Example 1 and Application Examples 5-6, it can be seen that in the purification process of the crude extract of gentian flower, the co-doping method of DAX-8 macroporous resin and CAD-40 macroporous resin can fully separate the moisturizing and soothing components, thereby improving the moisturizing and soothing effect of the gentian flower extract.

[0181] From the comparison of the data of Application Example 1 and Application Examples 7-9, it can be seen that in the preparation process of walnut seed oil, cellulase, pectinase and xylanase simultaneously enzymatically hydrolyze the walnut kernel, which can further promote the moisturizing and soothing effect of the prepared walnut seed oil.

[0182] From the comparison of the data of Application Example 1 and Application Examples 10-12, it can be seen that the dandelion extract, walnut seed oil and moringa seed oil have a significant synergistic effect in improving the moisturizing and soothing effect of the composition.

[0183] Test Example 3

[0184] Oil control efficacy evaluation:

[0185] Weigh 4g of each shower gel from Application Examples 1-12 and Comparative Application Examples 1-3 and evenly apply it to a 60mm diameter glass Petri dish. Place the dish in a 30°C incubator for 48 hours, then at 25°C for 30 minutes. Then, drop 40μL of oleic acid in the center of the dish. After 30 minutes, observe the spread of the oleic acid and measure the diameter of the oil stain. Perform three tests for each product and take the average value. The smaller the diameter of the oil stain, the stronger the product's oil-control ability.

[0186] The test results of the oil control effect of the shower gel obtained in each application example and comparative application example are shown in Table 4.

[0187] Table 4

[0188]

[0189]

[0190] It can be seen from the test data in Table 4 that the shower gel of the present invention has an excellent oil control effect.

[0191] From the comparison of the data of Application Example 1 and Comparative Application Example 1, it can be seen that the addition of plant extracts can further promote the effects of sodium pyrrolidonecarboxylate and recombinant type XVII collagen, thereby greatly improving the oil-control effect of the composition.

[0192] From the comparison of the data of Application Example 1 and Comparative Application Examples 2-3, it can be seen that sodium pyrrolidone carboxylate and recombinant type XVII collagen have a significant synergistic effect in oil control.

[0193] From the comparison of the data of Application Example 1 and Application Example 4, it can be seen that the microfluidic extraction method can fully extract the effective components in the gentian flower, thereby improving the oil control effect of the prepared gentian flower extract.

[0194] From the comparison of the data of Application Example 1 and Application Examples 5-6, it can be seen that in the purification process of the crude extract of gentian flower, the co-doping method of DAX-8 macroporous resin and CAD-40 macroporous resin can fully separate the oil-controlling effective components, thereby improving the oil-control effect of the gentian flower extract.

[0195] From the comparison of the data of Application Example 1 and Application Examples 7-9, it can be seen that in the preparation process of walnut seed oil, cellulase, pectinase and xylanase simultaneously enzymatically hydrolyze the walnut kernel, which can further promote the oil control effect of the prepared walnut seed oil.

[0196] From the comparison of the data of Application Example 1 and Application Examples 10-12, it can be seen that the dandelion extract, walnut seed oil and moringa seed oil have a significant synergistic effect in improving the oil-control effect of the composition.

[0197] The applicant declares that the present invention is illustrated by the above-described embodiments, but the present invention is not limited to the above-described embodiments. This does not mean that the present invention must rely on the above-described embodiments in order to be implemented. Those skilled in the art should understand that any improvements to the present invention, equivalent replacements for raw materials in the present invention, additions of auxiliary ingredients, and selection of specific methods, etc., fall within the scope of protection and disclosure of the present invention.

[0198] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, various simple modifications can be made to the technical solution of the present invention, and these simple modifications all fall within the scope of protection of the present invention.

[0199] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any appropriate manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

Claims

1. A moisturizing and oil-controlling composition, characterized in that: The moisturizing and oil-controlling composition comprises sodium pyrrolidone carboxylate, recombinant type XVII collagen and plant extracts.

2. The moisturizing and oil-controlling composition according to claim 1, wherein Calculated by weight, the moisturizing and oil-controlling composition comprises 5-10 parts of sodium pyrrolidone carboxylate, 1-7 parts of recombinant type XVII collagen and 0.1-1 part of plant extract.

3. The moisturizing and oil-controlling composition according to claim 1 or 2, characterized in that: The plant extracts include gentian flower extract, walnut seed oil and moringa seed oil; Preferably, the mass ratio of the gentian flower extract, walnut seed oil and moringa seed oil is 1:(0.5-3):(1-5).

4. The moisturizing and oil-controlling composition according to claim 3, characterized in that: The gentiana flower extract is prepared by a preparation method comprising the following steps: (1) mixing the gentian flower raw material with water and performing microfluidization extraction to obtain a gentian flower crude extract; (2) Purify the crude extract of gentiana flower using macroporous resin, and elute it with water and ethanol aqueous solution in sequence, collect the ethanol aqueous solution fraction, and dry it to obtain the gentiana flower extract.

5. The moisturizing and oil-controlling composition according to claim 4, characterized in that: The material-liquid ratio of the gentian flower raw material to water in step (1) is 1:(30-70) g / mL; Preferably, the temperature of the microfluidic extraction in step (1) is 40-80° C., and the pressure of the microfluidic extraction is 100-250 MPa; Preferably, the number of microfluidic extractions in step (1) is 1-4 times; Preferably, the macroporous resin in step (2) includes DAX-8 and / or CAD-40, preferably DAX-8 and CAD-40; Preferably, the mass ratio of the DAX-8 macroporous resin to the CAD-40 macroporous resin is 1:(1-3); Preferably, the volume percentage of ethanol in the ethanol aqueous solution in step (2) is 80-98%; Preferably, the flow rates of the water and ethanol aqueous solutions for elution in step (2) are independently 0.5-2 BV / h, and the amounts used are independently 1-5 BV.

6. The moisturizing and oil-controlling composition according to any one of claims 3 to 5, characterized in that: The walnut seed oil is prepared by a preparation method comprising the following steps: (I) mixing a raw material of walnut kernel with an aqueous solution of a complex enzyme to perform an enzymatic hydrolysis reaction, and drying to obtain an enzymatic hydrolysis product; (II) The enzymatic hydrolysis product is subjected to supercritical CO2 extraction to obtain walnut seed oil.

7. The moisturizing and oil-controlling composition according to claim 6, wherein: In step (I), the material-liquid ratio of the walnut kernel raw material to the aqueous solution of the complex enzyme is 1:(20-40) g / mL; Preferably, in the aqueous solution of the complex enzyme in step (I), the mass percentage of the complex enzyme is 0.1-1%; Preferably, the complex enzyme comprises cellulase, pectinase and xylanase; Preferably, the mass ratio of the cellulase, pectinase and xylanase is (3-8):(0.5-2):(1-5); Preferably, the temperature of the enzymatic hydrolysis reaction in step (I) is 40-60°C, and the enzymatic hydrolysis reaction time is 0.2-1h; Preferably, the temperature of the supercritical CO2 extraction in step (II) is 40-60°C, the pressure of the supercritical CO2 extraction is 30-50MPa, the time of the supercritical CO2 extraction is 0.5-2h, and the CO2 flow rate of the supercritical CO2 extraction is 10-40L / h.

8. The moisturizing and oil-controlling composition according to any one of claims 3 to 7, characterized in that: The Moringa seed oil is prepared by a preparation method comprising the following steps: The moringa seed raw material is mixed with petroleum ether and subjected to hot reflux extraction to obtain moringa seed oil; Preferably, the material-liquid ratio of the Moringa seed raw material to petroleum ether is 1:(3-10) g / mL; Preferably, the number of hot reflux extractions is 1-4 times, and the time for each hot reflux extraction is 2-6 hours.

9. A moisturizing and oil-controlling shower gel, characterized in that: The moisturizing and oil-controlling shower gel comprises the moisturizing and oil-controlling composition according to any one of claims 1 to 8, a surfactant, a chelating agent, a skin conditioning agent, and a solvent; Preferably, the surfactant includes any one or a combination of at least two of sodium laureth sulfate, sodium lauryl sulfate, sodium sulfate or lauryl alcohol; Preferably, the chelating agent comprises disodium edetate; Preferably, the skin conditioning agent comprises any one or a combination of at least two of niacinamide, sodium polyaspartate or butylene glycol; Preferably, the solvent comprises water; Preferably, the moisturizing and oil-controlling shower gel comprises, by mass, 1-5 parts of the moisturizing and oil-controlling composition according to any one of claims 1 to 8, 10-30 parts of a surfactant, 0.05-0.1 parts of a chelating agent, 5-10 parts of a skin conditioner, and 55-85 parts of a solvent.

10. A method for preparing the moisturizing and oil-controlling shower gel according to claim 9, characterized in that: The preparation method comprises the following steps: The solvent, surfactant and chelating agent are mixed and homogenized to obtain a mixed liquid; the mixed liquid is mixed and stirred with a moisturizing oil-controlling composition and a skin conditioner to obtain a moisturizing oil-controlling shower gel; Preferably, the speed of the mixing and homogenizing before obtaining the mixed liquid is 1000-3000 rpm, the temperature of the mixing and homogenizing is 80-90° C., and the time of the mixing and homogenizing is 10-40 min; Preferably, the mixing and stirring speed before obtaining the moisturizing and oil-controlling shower gel is 10-40 rpm, the mixing and stirring temperature is 42-45° C., and the mixing and stirring time is 10-40 min.

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