Digestive tract sampling device and method

The temperature control, sealing and cleaning functions of the digestive tract sampling device solve the problems of low cleaning efficiency and contamination of the mouse digestive tract mucosa, ensuring that the samples remain active at an appropriate temperature, and achieving efficient cleaning and preservation.

CN120665708APending Publication Date: 2025-09-19GUANGZHOU UNIV OF CHINESE MEDICINE SHENZHEN HOSPITAL (FUTIAN)
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Patent Information

Application Number
CN202510578744.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-07
Publication Date
2025-09-19

AI Technical Summary

Technical Problem

Existing methods for cleaning mouse digestive tract mucosa are inefficient and easily contaminate samples, leading to mucosal degradation and tissue apoptosis. They cannot meet the high demands of sample preparation and are not easy to preserve after cleaning.

Method used

A digestive tract sampling device is used, including a temperature regulating mechanism, a sealing mechanism and a loading mechanism. By regulating the temperature, sealing, disinfecting and cleaning components, it ensures that the sample remains active at an appropriate temperature and is efficiently cleaned and disinfected.

Benefits of technology

The sample can be kept active at a suitable temperature, the cleaning effect is ensured, the integrity and activity of the sample are improved, the storage and subsequent processing are convenient, and the efficiency and effect of the equipment are improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of biological experiment equipment, in particular to an alimentary canal sampling device and method, and the alimentary canal sampling device comprises a temperature adjusting mechanism, a sealing mechanism and a loading mechanism. During use, the refrigeration sheet is mounted through the temperature conducting frame, so that the low-temperature side is tightly attached to the temperature conducting plate below the temperature conducting top frame, low temperature can be transferred to the interior of the space between the temperature conducting top frame and the temperature conducting top plate, and the low temperature can be gradually transferred to the temperature conducting frame through the temperature conducting top plate and can be diffused to the interior of the bottom frame at the same time; meanwhile, an exhaust fan and a circulating fan are controlled to be started, so that the circulating fan can inject air in the bottom frame into the space between the temperature guide top frame and the temperature guide top plate, and then low-temperature air between the temperature guide top frame and the temperature guide top plate can be conveyed into the exhaust frame through the exhaust fan; and then the low-temperature air can be continuously conveyed to the top of the carrier plate through the exhaust frame.
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Description

Technical Field

[0001] The present invention belongs to the technical field of biological experimental equipment, and in particular relates to a digestive tract sampling device and a method thereof. Background Art

[0002] In the field of biomedical research, the study of mouse gastrointestinal mucosa is an important direction. The cleaning of mouse digestive tract mucosa currently relies mainly on manual operation. This method is not only inefficient, but also easily contaminates samples and damages the mucosa during the cleaning process. Prolonged operation may also lead to mucosal degradation and tissue apoptosis, resulting in the mucosa being unable to meet the sample preparation needs such as single-cell sequencing, spatial metabolism, spatial transcription, etc., which have high requirements for the integrity and activity of sample cells and tissues, as well as high requirements for sample microbial detection.

[0003] However, existing cleaning methods are difficult to clean, and there are problems such as easy contamination of samples, long-term operation leading to mucosal degradation and tissue apoptosis, and substandard samples affecting sequencing results. In addition, the samples are not convenient to store after cleaning. Summary of the Invention

[0004] The purpose of the present invention is to provide a digestive tract sampling device and method that can conveniently clean the material to be processed and ensure the activity effect of the material to be processed during a long processing time.

[0005] The technical solution adopted by the present invention is as follows: a digestive tract sampling device, comprising: a temperature regulating mechanism for regulating the ambient temperature during the sampling process;

[0006] a sealing mechanism, used for sealing and disinfecting the interior space of the temperature regulating mechanism, wherein the sealing mechanism is provided on the temperature regulating mechanism; and

[0007] The carrying mechanism is used for carrying the material to be collected, and the carrying mechanism is arranged on the temperature regulating mechanism.

[0008] Among them, the temperature control mechanism includes a bottom frame, a temperature conduction frame and a temperature conduction component. The temperature conduction frame is slidably inserted into the inner wall of one side of the bottom frame, and one end of the temperature conduction frame extends to the outside of the bottom frame. Temperature conduction plates are inserted at the top and bottom of the temperature conduction frame, and the temperature conduction component is arranged on the bottom frame.

[0009] Among them, the temperature conduction components include a temperature conduction top frame, a temperature conduction top plate, a temperature conduction rack, an air guide frame, an adjustment frame, an adjustment column, an exhaust frame and an extension frame. The temperature conduction top frame is fixedly connected to the inner bottom surface of the bottom frame, the temperature conduction top plate is slidably inserted on the top of the temperature conduction top frame, the temperature conduction rack is slidably inserted on the top of the temperature conduction top plate, the air guide frame is connected to the bottom of the bottom frame, the adjustment frame is connected to the outer surface of one side of the air guide frame, an exhaust port is opened at the bottom of the adjustment frame, the adjustment column is rotatably connected to the inside of the adjustment frame, the extension frame is connected to the outer surface of one side of the adjustment frame, and the exhaust frame is inserted on the inner surface wall on the other side of the bottom frame.

[0010] The top of one of the heat conduction plates is in contact with the bottom of the heat conduction top frame, and the bottom of the other heat conduction plate extends into the interior of the air guide frame.

[0011] Among them, an exhaust groove is provided on the bottom surface of the bottom frame, the interior of the exhaust groove is connected to the interior of the extension frame, an air guide plate is fixedly connected to the interior of the exhaust groove, an exhaust fan and a circulation fan are connected to the inner wall of one side of the temperature-conducting top frame, the interior of the exhaust fan is connected to the interior of the exhaust frame, and a plurality of heat dissipation fans are passed through the inner wall of one side of the air guide frame.

[0012] Among them, a drainage frame is inserted at the bottom of the bottom frame, a liquid guide plate is fixedly connected to the bottom surface of the drainage frame, filter frames are fixedly connected to the outer surfaces of both sides of the air guide frame, a shield is slidably inserted at the top of the bottom frame, a limiting strip is fixedly connected to the outer surface of one side of the adjustment frame, and an installation frame is inserted at the outer surface of one side of the bottom frame.

[0013] The sealing mechanism includes a first sealing cover and a second sealing cover, the second sealing cover is rotatably connected to the top of the bottom frame, the second sealing cover is rotatably connected to the top of the first sealing cover, and an ultraviolet sterilization lamp is fixedly connected to the inner wall of the second sealing cover.

[0014] In which, the carrying mechanism includes a carrying plate, a first movable plate, a second movable plate and a cleaning component, the carrying plate is slidably inserted between the bottom surface and the inner wall of the bottom frame, the top of the carrying plate is provided with a first slide groove, a second slide groove and a limit groove, the first movable plate and the second movable plate are both slidably inserted in the first slide groove, the tops of the first movable plate and the second movable plate are both rotatably connected to the limit bolt, the outer surface of each limit bolt is threadedly connected to the limit block, each limit block is slidably embedded in the second slide groove, and the cleaning component is arranged on the top of the first movable plate.

[0015] In which, the cleaning component includes a liquid storage frame, a micro water pump, a turntable, a liquid guide tube and a steering tube. The liquid storage frame and the micro water pump are fixedly connected to the top of the first movable plate. The input end and the output end of the micro water pump are respectively connected to a liquid inlet pipe and a liquid discharge pipe. One end of the liquid inlet pipe extends to the inside of the liquid storage frame. The turntable is rotatably connected to the top of the first movable plate. The liquid guide tube is inserted into the top of the turntable. One end of the liquid guide tube is fixedly connected to one end of the liquid discharge tube, and the steering tube is rotatably connected to the other end of the liquid guide tube.

[0016] A method for obtaining a digestive tract sample comprises the following steps:

[0017] S1. Material processing: The loading mechanism can conveniently place and remove the bottom frame through the loading plate, and the limiting groove on the top of the loading plate allows the utensils to be placed stably on the top of the loading plate. The cleaning solution can be temporarily stored through the liquid storage frame, and then the micro water pump is controlled to start, so that the micro water pump can transport the cleaning solution to the inside of the liquid guide tube through the liquid inlet pipe and the liquid discharge pipe, and then the use angle of the turntable and the steering tube is adjusted by rotation, so that the steering tube can fully rinse the material to be processed. At the same time, by rotating the limiting bolt, the limiting bolt is limited to the position of the second slide groove, so that the limiting block can squeeze the second slide groove to limit the use position of the first movable plate and the second movable plate, so that the second movable plate can temporarily adjust the use position of the utensils, and the waste solution generated by cleaning flows into the inside of the liquid discharge frame through the limiting groove, and then is discharged through the liquid discharge frame;

[0018] S2. Temperature regulation: The refrigeration plate is installed and set through the temperature conducting frame, so that the low temperature side is close to the temperature conducting plate below the temperature conducting top frame, and then the low temperature can be transferred to the space between the temperature conducting top frame and the temperature conducting top plate, so that the low temperature can be gradually transferred to the temperature conducting rack through the temperature conducting top plate and diffused to the inside of the bottom frame, thereby reducing the overall temperature inside the bottom frame. At the same time, the exhaust fan and the circulation fan are started by controlling the circulation fan to inject the air inside the bottom frame into the space between the temperature conducting top frame and the temperature conducting top plate, thereby allowing the exhaust fan to The low-temperature air between the temperature-conducting top frame and the temperature-conducting top plate is transported to the inside of the exhaust frame, and then the low-temperature air can be continuously transported to the top of the carrier plate through the exhaust frame, so that the flowing low-temperature air can maintain the ambient temperature of the material to be processed on the top of the carrier plate, thereby ensuring that the material to be processed can remain active for a long time in a suitable temperature environment, thereby ensuring the use effect of the material to be processed after processing. At the same time, the processed material to be processed can be divided into pre-cooled EP tubes, and the space between the first sealing cover, the second sealing cover and the bottom frame can provide a temporary storage space;

[0019] S3. Cleaning process: The heat exhaust side of the refrigeration plate is close to the heat conduction plate above the air guide frame, and the high temperature generated by the refrigeration plate is transferred to the inside of the air guide frame through the heat conduction plate, and then the heat dissipation fan is started by control, so that the heat dissipation fan can inject the outside air into the air guide frame, and the flowing air transports the excess heat to the inside of the adjustment frame. Under the obstruction of the adjustment column, the high-temperature flowing air can be discharged through the exhaust port, thereby ensuring the low-temperature environment inside the bottom frame. When the use is completed and disinfected, electrolyzed ozone water is used to rinse the residue inside the bottom frame and the drain frame, and then the adjustment column is rotated to use the angle, so that the air guide frame is connected with the inside of the extension frame through the adjustment frame and the adjustment column, so that the flowing air can be injected into the bottom frame through the extension frame and the exhaust slot. At the same time, inside the air guide piece, it can accelerate the rapid dissipation of residual moisture inside the drain frame and the bottom frame, and then ensure the dryness of the inside of the bottom frame. At this time, the first sealing cover and the second sealing cover are rotated to form a sealed space between the first sealing cover, the second sealing cover and the bottom frame, and then the ultraviolet germicidal lamp is started by control, so that the ultraviolet germicidal lamp can not hinder the surrounding environment while performing efficient sterilization treatment of the internal environment of the bottom frame, which is convenient for reuse of the equipment and improves the actual use effect of the equipment. At the same time, the use direction of the temperature conducting frame can be adjusted by rotation, and the direction of the low-temperature surface and the high-temperature surface can be adjusted, so that the heat generated by the operation of the refrigeration plate can be transferred to the inside of the bottom frame through the temperature conducting top frame, so that the equipment can provide different processing temperature environments.

[0020] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are:

[0021] (1) In the present invention, when in use, the refrigeration plate is installed and arranged through the heat conduction frame, so that the low temperature side is close to the heat conduction plate below the heat conduction top frame, and then the low temperature can be transferred to the space between the heat conduction top frame and the heat conduction top plate, so that the low temperature can be gradually transferred to the heat conduction rack through the heat conduction top plate and diffuse into the bottom frame, thereby reducing the overall temperature inside the bottom frame, and at the same time, by controlling the start-up of the exhaust fan and the circulation fan, the circulation fan can inject the air inside the bottom frame into the space between the heat conduction top frame and the heat conduction top plate, thereby allowing the exhaust fan to transfer the heat conduction top frame and the heat conduction top plate to the heat conduction rack. The low-temperature air between the warm top plates is transported to the inside of the exhaust frame, and then the low-temperature air can be continuously transported to the top of the carrier plate through the exhaust frame, so that the flowing low-temperature air can maintain the ambient temperature of the material to be processed on the top of the carrier plate, thereby ensuring that the material to be processed can remain active for a long time in a suitable temperature environment, thereby ensuring the use effect of the material to be processed after processing. At the same time, the processed material to be processed can be packaged into pre-cooled EP tubes, and the space between the first sealing cover, the second sealing cover and the bottom frame can provide a temporary storage space, so that the equipment can efficiently perform its functions.

[0022] (2) In the present invention, the heat dissipation side of the refrigeration plate is in close contact with the heat conduction plate above the air guide frame, and then the high temperature generated by the refrigeration plate is transferred to the inside of the air guide frame through the heat conduction plate, and then the heat dissipation fan is started by control, so that the heat dissipation fan can inject external air into the air guide frame, and the flowing air transports the excess heat to the inside of the adjustment frame. Under the obstruction of the adjustment column, the high-temperature flowing air can be discharged through the exhaust port, thereby ensuring the low-temperature environment inside the bottom frame. When the use is completed and disinfected, electrolytic ozone water is used to flush the residue inside the bottom frame and the drainage frame, and then the adjustment column is rotated to use the angle, so that the air guide frame passes through the adjustment frame and the adjustment column and the extension The interior of the extension frame is connected, so that the flowing air can be injected into the bottom frame through the extension frame and the exhaust slot. At the same time, under the guidance of the air guide plate, the flowing air can flow into the interior of the drainage frame, thereby accelerating the rapid dissipation of residual moisture inside the drainage frame and the bottom frame, and then ensuring the dryness of the inside of the bottom frame. At this time, the first sealing cover and the second sealing cover are rotated to form a sealed space between the first sealing cover, the second sealing cover and the bottom frame, and then the ultraviolet sterilization lamp is started by control, so that the ultraviolet sterilization lamp can perform efficient sterilization treatment of the internal environment of the bottom frame without interfering with the surrounding environment, thereby facilitating the reuse of the equipment and improving the actual use effect of the equipment.

[0023] (3) In the present invention, the direction of use of the temperature conducting frame is adjusted by rotating, and the direction of the low-temperature surface and the high-temperature surface can be adjusted, so that the heat generated by the operation of the refrigeration plate can be transferred to the inside of the bottom frame through the temperature conducting top frame, so that the equipment can provide different processing temperature environments. The carrier plate enables the loading mechanism to conveniently place and remove the bottom frame. At the same time, the limiting groove on the top of the carrier plate facilitates the use of utensils to be stably placed on the top of the carrier plate. The liquid storage frame can be used to temporarily store the cleaning solution, and the micro water pump can be started by control, so that the micro water pump can pass the cleaning solution through the liquid inlet pipe and the liquid discharge pipe. The solution is transported to the inside of the liquid guide tube, and then the use angle of the turntable and the steering tube is adjusted by rotation, so that the steering tube can fully rinse the material to be processed. At the same time, by rotating the limit bolt, the limit bolt is limited to the position of the second slide groove, so that the limit block can squeeze the second slide groove to limit the use position of the first movable plate and the second movable plate, so that the second movable plate can temporarily adjust the use position with the use instrument. The waste solution generated by cleaning flows into the drain frame through the limit groove and is then discharged through the drain frame, which facilitates the subsequent cleaning and disinfection of the equipment and improves the actual use effect of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a first perspective stereogram of the present invention;

[0025] Figure 2 is a second perspective stereogram of the present invention;

[0026] Figure 3 A partially cutaway perspective view of the present invention from a first viewing angle;

[0027] Figure 4 It is a partially cutaway and expanded perspective view of the present invention from a first viewing angle;

[0028] Figure 5 A partially cutaway perspective view of the temperature control mechanism of the present invention from a first viewing angle;

[0029] Figure 6 For the present invention Figure 5 Enlarged view of point A in the middle;

[0030] Figure 7 For the present invention Figure 5 Enlarged view of point B in the middle;

[0031] Figure 8 This is a sectional and expanded perspective view of the temperature control mechanism of the present invention from a first viewing angle;

[0032] Figure 9 For the present invention Figure 8 Enlarged view of point C in the middle;

[0033] Figure 10 This is a sectional and expanded perspective view of the temperature control mechanism of the present invention from a second viewing angle;

[0034] Figure 11 For the present invention Figure 10 Enlarged view of point D in the middle;

[0035] Figure 12 This is an expanded perspective view of the sealing mechanism of the present invention;

[0036] Figure 13 A partially sectional expanded perspective view of the object carrying mechanism of the present invention;

[0037] Figure 14 For the present invention Figure 13 Enlarged view of point E in the middle.

[0038] Markings in the figure:

[0039] 1. Temperature control mechanism; 101. Bottom frame; 102. Shield; 103. Drain frame; 104. Liquid guide plate; 105. Exhaust slot; 106. Air guide plate; 107. Extension frame; 108. Adjustment frame; 109. Adjustment column; 110. Limiting strip; 111. Air guide frame; 112. Cooling fan; 113. Mounting frame; 114. Filter frame; 115. Temperature guide frame; 116. Temperature guide plate; 117. Temperature guide top frame; 118. Exhaust fan; 119. Circulation fan; 120. Temperature guide top plate; 121. Temperature guide rack; 122. Exhaust frame;

[0040] 2. Sealing mechanism; 201. First sealing cover; 202. Second sealing cover; 203. Ultraviolet germicidal lamp;

[0041] 3. Carrying mechanism; 301. Carrying plate; 302. Limiting groove; 303. Second slide groove; 304. First slide groove; 305. First movable plate; 306. Turntable; 307. Liquid guide tube; 308. Steering tube; 309. Micro water pump; 310. Liquid discharge tube; 311. Liquid inlet tube; 312. Liquid storage frame; 313. Limiting bolt; 314. Limiting block; 315. Second movable plate. DETAILED DESCRIPTION

[0042] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0043] For example, see Figures 1-4 A digestive tract sampling device is composed of a temperature regulating mechanism 1, a sealing mechanism 2 and a loading mechanism 3.

[0044] The details are as follows:

[0045] See also Figure 5-Figure 11, the temperature regulating mechanism 1 is used to regulate the ambient temperature during the material collection process, and includes a bottom frame 101, a temperature conducting frame 115 and a temperature conducting component. The temperature conducting frame 115 is slidably inserted into the inner surface wall of one side of the bottom frame 101, and one end of the temperature conducting frame 115 extends to the outside of the bottom frame 101. The top and bottom of the temperature conducting frame 115 are both inserted with temperature conducting plates 116. The temperature conducting component is arranged on the bottom frame 101. The temperature conducting component includes a temperature conducting top frame 117, a temperature conducting top plate 120, a temperature conducting rack 121, an air guide frame 111, an adjusting frame 108, an adjusting column 109, an exhaust frame 122 and an extension frame 107. The temperature conducting top frame 117 is fixedly connected to the inner bottom surface of the bottom frame 101, the temperature conducting top plate 120 is slidably inserted into the top of the temperature conducting top frame 117, and the temperature conducting rack 121 is slidably inserted into the top of the temperature conducting top plate 120. The wind frame 111 is connected and arranged at the bottom of the bottom frame 101, the adjustment frame 108 is connected and arranged on the outer surface of one side of the wind guide frame 111, an exhaust port is provided at the bottom of the adjustment frame 108, the adjustment column 109 is rotatably connected to the inside of the adjustment frame 108, the extension frame 107 is connected and arranged on the outer surface of one side of the adjustment frame 108, the exhaust frame 122 is inserted into the inner surface wall of the other side of the bottom frame 101, the top of one of the heat conducting plates 116 is fitted with the bottom of the heat conducting top frame 117, and the bottom of the other heat conducting plate 116 extends to the inside of the wind guide frame 111, an exhaust slot 105 is provided on the bottom surface of the interior of the bottom frame 101, the interior of the exhaust slot 105 is connected to the interior of the extension frame 107, the exhaust slot 105 is fixedly connected with an air guide plate 106, and the inner surface wall of the heat conducting top frame 117 is connected and provided with an exhaust fan. The fan 118 and the circulating fan 119 are connected, the interior of the exhaust fan 118 is connected to the interior of the exhaust frame 122, and a plurality of heat dissipation fans 112 are passed through the inner wall of one side of the air guide frame 111. A drainage frame 103 is inserted at the bottom of the bottom frame 101, and a liquid guide plate 104 is fixedly connected to the bottom surface of the drainage frame 103. The outer surfaces of both sides of the air guide frame 111 are fixedly connected to the filter frames 114. A shield plate 102 is slidingly inserted at the top of the bottom frame 101. A limit strip 110 is fixedly connected to the outer surface of one side of the adjustment frame 108. A mounting frame 113 is inserted on the outer surface of one side of the bottom frame 101. The refrigeration plate is installed and set through the temperature conducting frame 115, so that the low temperature side is close to the temperature conducting plate 116 below the temperature conducting top frame 117, and then the low temperature can be transferred to the temperature conducting top frame 117 and the temperature conducting top frame 117. The low temperature inside the space between the plates 120 can be gradually transferred to the temperature conducting rack 121 through the temperature conducting top plate 120 and can be diffused to the inside of the bottom frame 101, thereby reducing the overall temperature inside the bottom frame 101. At the same time, by controlling the start-up of the exhaust fan 118 and the circulation fan 119, the circulation fan 119 can inject the air inside the bottom frame 101 into the space between the temperature conducting top frame 117 and the temperature conducting top plate 120, thereby enabling the exhaust fan 118 to transport the low-temperature air between the temperature conducting top frame 117 and the temperature conducting top plate 120 to the exhaust frame 122, and then the low-temperature air can be continuously transported to the top of the carrier plate 301 through the exhaust frame 122, so that the flowing low-temperature air can maintain the ambient temperature of the material to be processed on the top of the carrier plate 301.This ensures that the material to be processed can maintain its activity for a long time under a suitable temperature environment, thereby ensuring the use effect of the material to be processed after processing. At the same time, the processed material to be processed can be divided into pre-cooled EP tubes, and then the space between the first sealing cover 201, the second sealing cover 202 and the bottom frame 101 can provide a temporary storage space, so that the equipment can efficiently perform its functions. The heat exhaust side of the refrigeration plate is close to the temperature guide plate 116 above the air guide frame 111, and then the high temperature generated by the refrigeration plate is transferred to the inside of the air guide frame 111 through the temperature guide plate 116, and then the heat dissipation fan 112 is started by control, so that the heat dissipation fan 112 can inject external air into the inside of the air guide frame 111, and the flowing air transports excess heat to the inside of the adjustment frame 108. Under the obstruction of the adjusting column 109, the high-temperature flowing air can be discharged through the exhaust port, thereby ensuring a low-temperature environment inside the bottom frame 101. When the use is completed for disinfection, electrolyzed ozone water is used to rinse the residue inside the bottom frame 101 and the drain frame 103. Then, by rotating the use angle of the adjusting column 109, the air guide frame 111 is connected to the interior of the extension frame 107 through the adjusting frame 108 and the adjusting column 109, so that the flowing air can be injected into the bottom frame 101 through the extension frame 107 and the exhaust slot 105. At the same time, under the guidance of the air guide piece 106, the flowing air can flow into the drain frame 103, thereby accelerating the rapid dissipation of residual water inside the drain frame 103 and the bottom frame 101, thereby ensuring the dryness of the bottom frame 101.

[0046] See also Figure 12 , the sealing mechanism 2 is used to seal and disinfect the internal space of the temperature regulating mechanism 1. The sealing mechanism 2 is arranged on the temperature regulating mechanism 1, and includes a first sealing cover 201 and a second sealing cover 202. The second sealing cover 202 is rotatably connected to the top of the bottom frame 101, and the second sealing cover 202 is rotatably connected to the top of the first sealing cover 201. The inner wall of the second sealing cover 202 is fixedly connected with an ultraviolet germicidal lamp 203. The first sealing cover 201 and the second sealing cover 202 are rotated to form a sealed space between the first sealing cover 201, the second sealing cover 202 and the bottom frame 101. Then, by controlling to start the ultraviolet germicidal lamp 203, the ultraviolet germicidal lamp 203 can perform efficient sterilization treatment on the internal environment of the bottom frame 101 without interfering with the surrounding environment, thereby facilitating the reuse of the equipment and improving the actual use effect of the equipment. At the same time, by rotating and adjusting the use direction of the temperature conducting frame 115, the direction of the low temperature surface and the high temperature surface can be adjusted, so that the heat generated by the operation of the refrigeration plate can be transferred to the inside of the bottom frame 101 through the temperature conducting top frame 117, thereby enabling the equipment to provide different processing temperature environments;

[0047] See also Figure 13 and Figure 14The loading mechanism 3 is used to carry the material to be taken. The loading mechanism 3 is arranged on the temperature regulating mechanism 1, and includes a loading plate 301, a first movable plate 305, a second movable plate 315 and a cleaning component. The loading plate 301 is slidably inserted between the bottom surface and the inner wall of the bottom frame 101. The top of the loading plate 301 is provided with a first sliding groove 304, a second sliding groove 303 and a limiting groove 302. The first movable plate 305 and the second movable plate 315 are both slidably inserted into the first sliding groove 304. The tops of the first movable plate 305 and the second movable plate 315 are both rotatably connected to the limiting bolt 313. The outer surface of each limiting bolt 313 is threadedly connected to the limiting block 31 4. Each limit block 314 is slidably embedded in the second slide groove 303. The cleaning component is set on the top of the first movable plate 305. The cleaning component includes a liquid storage frame 312, a micro water pump 309, a turntable 306, a liquid guide tube 307 and a steering tube 308. The liquid storage frame 312 and the micro water pump 309 are fixedly connected to the top of the first movable plate 305. The input end and output end of the micro water pump 309 are respectively connected to the liquid inlet tube 311 and the liquid discharge tube 310. One end of the liquid inlet tube 311 extends into the interior of the liquid storage frame 312. The turntable 306 is rotatably connected to the top of the first movable plate 305. The liquid guide tube 307 is inserted at the top of the turntable 306. One end of the liquid guide tube 307 is fixedly connected to one end of the liquid discharge tube 310, and the steering tube 308 is rotatably connected to the other end of the liquid guide tube 307. The carrier plate 301 enables the carrying mechanism 3 to conveniently place and remove the bottom frame 101. At the same time, the limiting groove 302 on the top of the carrier plate 301 facilitates the stable placement of utensils on the top of the carrier plate 301. The liquid storage frame 312 can be used to temporarily store the cleaning solution, and then the micro water pump 309 is started by control, so that the micro water pump 309 can transport the cleaning solution to the inside of the liquid guide tube 307 through the liquid inlet pipe 311 and the liquid discharge pipe 310, and then the turntable 306 and the liquid storage frame 312 are rotated to adjust the cleaning solution. The steering tube 308 is used at an angle so that the steering tube 308 can fully rinse the material to be processed. At the same time, by rotating the limit bolt 313, the limit bolt 313 is limited by the position of the second slide groove 303, so that the limit block 314 can squeeze the second slide groove 303 to limit the use position of the first movable plate 305 and the second movable plate 315, so that the second movable plate 315 can temporarily adjust the use position with the use tool. The waste solution generated by cleaning flows into the drain frame 103 through the limit groove 302, and is then discharged through the drain frame 103, thereby facilitating the subsequent cleaning and disinfection of the equipment and improving the actual use effect of the equipment.

[0048] The following is a detailed description of a method for obtaining a digestive tract sample provided by an embodiment of the present invention. The method includes the following steps:

[0049] Step 1, material processing: The carrier plate 301 enables the carrier mechanism 3 to conveniently place and remove the bottom frame 101. At the same time, the limiting groove 302 on the top of the carrier plate 301 facilitates the use of utensils to be stably placed on the top of the carrier plate 301. The liquid storage frame 312 can be used to temporarily store the cleaning solution. Then, by controlling and starting the micro water pump 309, the micro water pump 309 can transport the cleaning solution to the inside of the liquid guide tube 307 through the liquid inlet pipe 311 and the liquid discharge pipe 310. Then, by rotating and adjusting the use angle of the turntable 306 and the steering tube 308, the steering tube 308 can be adjusted. 308 can fully rinse the material to be processed. At the same time, by rotating the limit bolt 313, the limit bolt 313 is restricted in the position of the second chute 303, so that the limit block 314 can squeeze the second chute 303 to limit the use position of the first movable plate 305 and the second movable plate 315, so that the second movable plate 315 can temporarily adjust the use position of the use tool. The waste solution generated by cleaning flows into the drain frame 103 through the limit groove 302 and is then discharged through the drain frame 103, thereby facilitating subsequent cleaning and disinfection of the equipment and improving the actual use effect of the equipment.

[0050] Step 2, temperature adjustment: The refrigeration fin is installed and set through the temperature conducting frame 115, so that the low temperature side is close to the temperature conducting plate 116 below the temperature conducting top frame 117, and then the low temperature can be transferred to the space between the temperature conducting top frame 117 and the temperature conducting top plate 120, so that the low temperature can be gradually transferred to the temperature conducting rack 121 through the temperature conducting top plate 120 and can be diffused to the inside of the bottom frame 101, thereby reducing the overall temperature inside the bottom frame 101, and at the same time, by controlling the start-up of the exhaust fan 118 and the circulation fan 119, the circulation fan 119 can inject the air inside the bottom frame 101 into the space between the temperature conducting top frame 117 and the temperature conducting top plate 120, thereby allowing the exhaust fan 118 to pass through the exhaust fan 118. The low-temperature air between the temperature-conducting top frame 117 and the temperature-conducting top plate 120 can be transported to the inside of the exhaust frame 122, and then the low-temperature air can be continuously transported to the top of the carrier plate 301 through the exhaust frame 122, so that the flowing low-temperature air can maintain the ambient temperature of the material to be processed on the top of the carrier plate 301, thereby ensuring that the material to be processed can remain active for a long time in a suitable temperature environment, thereby ensuring the use effect of the material to be processed after processing. At the same time, the processed material to be processed can be divided into pre-cooled EP tubes, and the space between the first sealing cover 201, the second sealing cover 202 and the bottom frame 101 can provide a temporary storage space, so that the equipment can efficiently perform its functions;

[0051] Step 3, cleaning treatment: the heat exhaust side of the refrigeration plate is close to the heat conduction plate 116 above the air guide frame 111, and then the high temperature generated by the refrigeration plate is transferred to the inside of the air guide frame 111 through the heat conduction plate 116, and then the heat dissipation fan 112 is started by control, so that the heat dissipation fan 112 can inject the outside air into the air guide frame 111, and the flowing air transports the excess heat to the inside of the adjustment frame 108. Under the obstruction of the adjustment column 109, the high-temperature flowing air can be discharged through the exhaust port, thereby ensuring the low temperature environment inside the bottom frame 101. When the use is completed and disinfected, electrolyzed ozone water is used to rinse the residue inside the bottom frame 101 and the drain frame 103, and then the adjustment column 109 is rotated to use the angle, so that the air guide frame 111 is connected to the inside of the extension frame 107 through the adjustment frame 108 and the adjustment column 109, so that the flowing air can be injected into the inside of the bottom frame 101 through the extension frame 107 and the exhaust slot 105. At this time, under the guidance of the air guide plate 106, the flowing air can flow into the drain frame 103, thereby accelerating the rapid dissipation of residual moisture in the drain frame 103 and the bottom frame 101, and then ensuring the drying of the bottom frame 101. At this time, the first sealing cover 201 and the second sealing cover 202 are rotated to form a sealed space between the first sealing cover 201, the second sealing cover 202 and the bottom frame 101, and then the ultraviolet sterilization lamp 203 is started by control, so that the ultraviolet sterilization lamp 203 can not interfere with the surrounding environment while performing efficient sterilization treatment of the internal environment of the bottom frame 101, which is convenient for reuse of the equipment and improves the actual use effect of the equipment. At the same time, by rotating and adjusting the use direction of the temperature conducting frame 115, the direction of the low temperature surface and the high temperature surface can be adjusted, so that the heat generated by the operation of the refrigeration plate can be transferred to the inside of the bottom frame 101 through the temperature conducting top frame 117, so that the equipment can provide different processing temperature environments.

[0052] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A digestive tract sampling device, characterized in that: include: A temperature regulating mechanism (1) is used to regulate the ambient temperature during the sampling process; A sealing mechanism (2) for performing a sealing and disinfecting process on the internal space of the temperature regulating mechanism (1), wherein the sealing mechanism (2) is arranged on the temperature regulating mechanism (1); and The carrying mechanism (3) is used for carrying the material to be collected, and the carrying mechanism (3) is arranged on the temperature regulating mechanism (1).

2. The digestive tract sampling device according to claim 1, characterized in that: The temperature regulating mechanism (1) comprises a bottom frame (101), a temperature conducting frame (115) and a temperature conducting component. The temperature conducting frame (115) is slidably inserted into an inner surface wall of one side of the bottom frame (101), and one end of the temperature conducting frame (115) extends to the outside of the bottom frame (101). Temperature conducting plates (116) are inserted into the top and bottom of the temperature conducting frame (115). The temperature conducting component is arranged on the bottom frame (101).

3. The digestive tract sampling device according to claim 2, characterized in that: The heat conducting component comprises a heat conducting top frame (117), a heat conducting top plate (120), a heat conducting rack (121), an air guiding frame (111), an adjusting frame (108), an adjusting column (109), an air exhaust frame (122) and an extension frame (107); the heat conducting top frame (117) is fixedly connected to the inner bottom surface of the bottom frame (101); the heat conducting top plate (120) is slidably inserted on the top of the heat conducting top frame (117); the heat conducting rack (121) is slidably inserted on the heat conducting top plate (121); 0) top, the air guide frame (111) is connected and arranged on the bottom of the bottom frame (101), the adjustment frame (108) is connected and arranged on the outer surface of one side of the air guide frame (111), an air outlet is opened at the bottom of the adjustment frame (108), the adjustment column (109) is rotatably connected to the inside of the adjustment frame (108), the extension frame (107) is connected and arranged on the outer surface of one side of the adjustment frame (108), and the exhaust frame (122) is inserted into the inner surface wall of the other side of the bottom frame (101).

4. The digestive tract sampling device according to claim 3, characterized in that: The top of one of the heat conducting plates (116) is in contact with the bottom of the heat conducting top frame (117), and the bottom of the other heat conducting plate (116) extends into the interior of the air guide frame (111).

5. The digestive tract sampling device according to claim 4, characterized in that: An exhaust slot (105) is provided on the bottom surface of the bottom frame (101), the interior of the exhaust slot (105) is connected to the interior of the extension frame (107), an air guide plate (106) is fixedly connected to the interior of the exhaust slot (105), an exhaust fan (118) and a circulation fan (119) are connected to the inner surface wall of one side of the heat-conducting top frame (117), the interior of the exhaust fan (118) is connected to the interior of the exhaust frame (122), and a plurality of heat dissipation fans (112) are passed through the inner surface wall of one side of the air guide frame (111).

6. The digestive tract sampling device according to claim 5, characterized in that: A liquid drain frame (103) is inserted at the bottom of the bottom frame (101), a liquid guide plate (104) is fixedly connected to the inner bottom surface of the liquid drain frame (103), filter frames (114) are fixedly connected to the outer surfaces of both sides of the air guide frame (111), a shielding plate (102) is slidably inserted at the top of the bottom frame (101), a limiting strip (110) is fixedly connected to the outer surface of one side of the adjustment frame (108), and a mounting frame (113) is inserted at the outer surface of one side of the bottom frame (101).

7. The digestive tract sampling device according to claim 6, characterized in that: The sealing mechanism (2) comprises a first sealing cover (201) and a second sealing cover (202), wherein the second sealing cover (202) is rotatably connected to the top of the bottom frame (101), the second sealing cover (202) is rotatably connected to the top of the first sealing cover (201), and an ultraviolet germicidal lamp (203) is fixedly connected to the inner surface wall of the second sealing cover (202).

8. The digestive tract sampling device according to claim 7, characterized in that: The object carrying mechanism (3) comprises a carrying plate (301), a first movable plate (305), a second movable plate (315) and a cleaning component. The carrying plate (301) is slidably inserted between the inner bottom surface and the inner surface wall of the bottom frame (101). The top of the carrying plate (301) is provided with a first sliding groove (304), a second sliding groove (303) and a limiting groove (302). The first movable plate (305) and the second movable plate (315) are both slidably inserted into the first sliding groove (304). The tops of the first movable plate (305) and the second movable plate (315) are both rotatably connected to the limiting bolt (313). The outer surface of each limiting bolt (313) is threadedly connected to the limiting block (314). Each limiting block (314) is slidably embedded in the second sliding groove (303). The cleaning component is arranged on the top of the first movable plate (305).

9. The digestive tract sampling device according to claim 8, characterized in that: The cleaning component comprises a liquid storage frame (312), a micro water pump (309), a turntable (306), a liquid guide tube (307) and a steering tube (308). The liquid storage frame (312) and the micro water pump (309) are both fixedly connected to the top of the first movable plate (305). The input end and the output end of the micro water pump (309) are respectively connected to a liquid inlet tube (311) and a liquid discharge tube (310). One end of the liquid inlet tube (311) extends into the interior of the liquid storage frame (312). The turntable (306) is rotatably connected to the top of the first movable plate (305). The liquid guide tube (307) is inserted into the top of the turntable (306). One end of the liquid guide tube (307) is fixedly connected to one end of the liquid discharge tube (310). The steering tube (308) is rotatably connected to the other end of the liquid guide tube (307).

10. A method for obtaining digestive tract samples, characterized in that: The digestive tract sampling device described in claim 9 comprises the following steps: S1. Material processing: The carrier plate (301) enables the carrier mechanism (3) to conveniently place and remove the bottom frame (101). At the same time, the limiting groove (302) on the top of the carrier plate (301) allows the container to be stably placed on the top of the carrier plate (301). The liquid storage frame (312) allows temporary storage of the cleaning solution. Then, the micro water pump (309) is controlled to start, and the micro water pump (309) is able to transport the cleaning solution to the inside of the liquid guide tube (307) through the liquid inlet pipe (311) and the liquid discharge pipe (310). Then, the turntable (306) and the steering pipe (310) are rotated to adjust the cleaning solution. 308) is used at an angle so that the steering tube (308) can fully rinse the material to be processed. At the same time, by rotating the limit bolt (313), the limit bolt (313) is limited by the position of the second chute (303), so that the limit block (314) can squeeze the second chute (303) to limit the use position of the first movable plate (305) and the second movable plate (315), so that the second movable plate (315) can temporarily adjust the use position of the tool. The waste solution generated by cleaning flows into the inside of the drain frame (103) through the limit groove (302) and is then discharged through the drain frame (103); S2. Temperature regulation: The refrigeration plate is installed and set through the heat conducting frame (115), so that the low temperature side is close to the heat conducting plate (116) below the heat conducting top frame (117), and then the low temperature can be transferred to the space between the heat conducting top frame (117) and the heat conducting top plate (120), so that the low temperature can be gradually transferred to the heat conducting rack (121) through the heat conducting top plate (120) and can be diffused to the inside of the bottom frame (101), thereby reducing the overall temperature inside the bottom frame (101), and at the same time, the exhaust fan (118) and the circulation fan (119) are started by control, so that the circulation fan (119) can inject the air inside the bottom frame (101) into the space between the heat conducting top frame (117) and the heat conducting top plate (120). , and then the low-temperature air between the temperature-conducting top frame (117) and the temperature-conducting top plate (120) can be transported to the inside of the exhaust frame (122) through the exhaust fan (118), and then the low-temperature air can be continuously transported to the top of the carrier (301) through the exhaust frame (122), so that the flowing low-temperature air can maintain the ambient temperature of the material to be processed on the top of the carrier (301), thereby ensuring that the material to be processed can maintain its activity for a long time under a suitable temperature environment, thereby ensuring the use effect of the material to be processed after processing, and at the same time, the processed material to be processed can be divided into pre-cooled EP tubes, and then the space between the first sealing cover (201), the second sealing cover (202) and the bottom frame (101) can provide a temporary storage space; S3, cleaning treatment: The heat dissipation side of the refrigeration plate is close to the heat conduction plate (116) above the air guide frame (111), and then the high temperature generated by the refrigeration plate is transferred to the inside of the air guide frame (111) through the heat conduction plate (116), and then the heat dissipation fan (112) is started by control, so that the heat dissipation fan (112) can inject the outside air into the inside of the air guide frame (111), and the flowing air transports the excess heat to the inside of the regulating frame (108), and under the obstruction of the regulating column (109), the high-temperature flowing air can pass through The exhaust port is used to discharge air, thereby ensuring a low-temperature environment inside the bottom frame (101). When the use is completed and disinfection is performed, electrolytic ozone water is used to flush the residue inside the bottom frame (101) and the drainage frame (103). Then, by rotating the adjustment column (109) to adjust the angle, the air guide frame (111) is connected to the inside of the extension frame (107) through the adjustment frame (108) and the adjustment column (109), thereby allowing the flowing air to be injected into the bottom frame (101) through the extension frame (107) and the exhaust slot (105). At the same time, under the guidance of the air guide plate (106), the flowing air can flow into the interior of the drain frame (103), thereby accelerating the rapid dissipation of residual moisture in the drain frame (103) and the bottom frame (101), thereby ensuring the drying of the bottom frame (101). At this time, the first sealing cover (201) and the second sealing cover (202) are rotated to form a sealed space between the first sealing cover (201), the second sealing cover (202) and the bottom frame (101). Then, by controlling the start of the ultraviolet sterilization lamp (203), the ultraviolet sterilization lamp (203) can perform efficient sterilization treatment of the internal environment of the bottom frame (101) without hindering the surrounding environment, thereby facilitating the reuse of the equipment and improving the actual use effect of the equipment. At the same time, by rotating the use direction of the temperature conducting frame (115), the direction of the low temperature surface and the high temperature surface can be adjusted, thereby allowing the heat generated by the operation of the refrigeration plate to be transferred to the inside of the bottom frame (101) through the temperature conducting top frame (117), thereby enabling the equipment to provide different processing temperature environments.