Test tube baby fertilized egg cell auxiliary culture device

Abstract

The invention discloses a test-tube baby fertilized egg cell auxiliary culture device which structurally comprises a storage box, a heating device and an operation panel, a sealing door is hinged to the upper portion of the storage box, a sealing rubber strip is arranged at the joint of the sealing door and the storage box, the whole storage box is made of heat preservation materials, and the heating device is arranged in the storage box. The device further comprises a culture tank, a driving device and a transmission device. The culture tank is rotationally arranged in the storage box. Supporting rods are fixedly arranged on the upper portion and the lower portion of the inner side of the storage box, and the driving equipment is arranged on the supporting rods. The driving equipment is movably connected with the culture tank, and the transmission equipment is arranged at the joint of the driving equipment and the culture tank. The invention belongs to the field of cell culture devices, and particularly relates to a test tube baby fertilized egg cell auxiliary culture device.

Description

Technical Field

[0001] The present invention belongs to the field of cell culture devices, and in particular relates to an in vitro fertilized egg cell auxiliary culture device. Background Art

[0002] As an important means of assisted reproduction, in vitro fertilization (IVF) technology involves the in vitro culture of fertilized eggs (zygotes). Currently, the stability of the in vitro culture environment directly impacts the development rate of zygotes and embryo quality. With the advancement of biomedical engineering, the requirements for controlling the culture environment are becoming increasingly stringent, with temperature uniformity and stability becoming key factors. Existing culture devices often employ static culture methods, making it difficult to achieve uniform temperature distribution and lacking dynamic regulation mechanisms, resulting in uneven development rates and even embryo failure.

[0003] In the prior art, common fertilized egg culture devices mainly include constant temperature chambers and static culture dishes. Constant temperature chambers use heating devices to maintain the temperature inside the chamber, but the air flow inside the chamber is poor, which can easily cause local temperature unevenness. Static culture dishes rely on the external ambient temperature, cannot be independently adjusted, and lack dynamic stirring function. In addition, some improvement plans have attempted to add stirring devices to the culture dishes, but too fast stirring speeds may cause centrifugal damage to the fertilized eggs, while too slow stirring speeds cannot effectively improve temperature distribution. Summary of the Invention

[0004] The present invention mainly solves the above technical problems.

[0005] To solve the above problems, the present invention adopts the following technical solution: The device for assisted culture of fertilized egg cells for in vitro fertilization proposed by the present invention comprises a storage box, a heating device, and an operation panel. The upper portion of the storage box is hinged with a sealing door, and a sealing rubber strip is provided at the connection. The storage box is entirely made of thermal insulation material. The heating device is disposed inside the storage box. The device also comprises a culture tank, a driving device, and a transmission device.

[0006] The culture tank is rotatably arranged inside the storage box;

[0007] Support rods are fixedly provided at the upper and lower parts of the inner side of the storage box, and the driving device is arranged on the support rods;

[0008] The driving device and the culture tank are movably connected, and the transmission device is arranged at the connection between the driving device and the culture tank.

[0009] Furthermore, a rotating rod is fixedly provided at the lower end of the culture tank, and the rotating rod is rotatably arranged at the bottom inner side of the storage box.

[0010] Furthermore, the driving device includes a sliding rod, and adjacent surfaces of the upper and lower support rods are provided with sliding grooves, and the sliding rod and the sliding groove are connected in a sliding engagement manner.

[0011] Furthermore, the driving device also includes a motor and an active rod. The motor is fixed to the inner side wall of the storage box. One end of the active rod is connected to the motor shaft, and the other end of the active rod is rotatably provided with a limit rod.

[0012] Furthermore, a moving frame is fixedly connected to one end of the sliding rod close to the motor. The moving frame is configured as an "X"-shaped structure and has an "X"-shaped limiting groove formed inside. The limiting rod and the limiting groove are connected in a sliding manner.

[0013] Furthermore, the middle section of the limiting groove is configured as an arc-shaped structure, and the radius is equal to the distance from the motor axis to the limiting rod axis.

[0014] Furthermore, the transmission device includes a rack and a gear, the rack is symmetrically fixed on both sides of the sliding rod, the gear is fixed at the connection between the rotating rod and the culture tank, and the gear and the rack are in meshing transmission connection.

[0015] Furthermore, a temperature sensor is provided on the culture tank, the operation panel is provided on the outside of the storage box, and a control chip is provided inside.

[0016] The beneficial effects achieved by the present invention using the above structure are as follows:

[0017] 1. The IVF fertilized egg cell auxiliary culture device proposed in this scheme makes the outer wall of the culture tank fully contact with the hot air through the reciprocating rotation of the culture tank, which significantly improves the temperature uniformity.

[0018] 2. The in vitro fertilized egg cell auxiliary culture device proposed in this scheme adopts a slow-speed motor and a limiting structure to avoid centrifugal damage to the fertilized egg cells caused by excessive rotation speed.

[0019] 3. The IVF fertilized egg cell assisted culture device proposed in this plan has a dynamic adjustment mechanism that effectively improves the uneven temperature distribution problem of traditional static culture methods, and improves the development rate and success rate of fertilized eggs. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0021] Figure 2 It is an overall cross-sectional schematic diagram of the present invention;

[0022] Figure 3 It is an enlarged schematic diagram of the first partial structure of the present invention;

[0023] Figure 4 It is an enlarged schematic diagram of the second local structure of the present invention.

[0024] Among them, 1. Storage box, 101. Sealing door, 102. Support rod, 103. Slide groove, 2. Culture tank, 201. Rotating rod, 3. Driving device, 301. Motor, 302. Active rod, 303. Limiting rod, 304. Moving rack, 305. Limiting groove, 306. Sliding rod, 4. Transmission equipment, 401. Rack, 402. Gear, 5. Heating equipment, 6. Operation panel.

[0025] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention. DETAILED DESCRIPTION

[0026] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0027] like Figure 1-4 As shown, the present invention proposes an in vitro fertilized egg cell assisted culture device, which includes a storage box 1, a heating device 5 and an operating panel 6. The storage box 1 is hinged with a sealing door 101 on the upper part, and a sealing rubber strip is provided at the connection. The storage box 1 is made of insulation material as a whole. The heating device 5 is arranged inside the storage box 1, and a temperature sensor is provided on the culture tank 2. The operating panel 6 is arranged on the outside of the storage box 1, and a control chip is provided inside, which is electrically connected to the motor 301, the heating device 5 and the temperature sensor respectively to control the rotation of the motor 301 and the temperature sensor and control the opening and closing of the heating device 5.

[0028] like Figure 1-4 As shown, it also includes a culture tank 2, a driving device 3 and a transmission device 4: the culture tank 2 is rotatably arranged inside the storage box 1, wherein a rotating rod 201 is fixed at the lower end of the culture tank 2, and the rotating rod 201 is rotatably arranged at the bottom inside the storage box 1.

[0029] like Figure 2-4As shown, support rods 102 are fixedly provided at the upper and lower parts of the inner side of the storage box 1, and the driving device 3 is arranged on the support rods 102; the driving device 3 and the culture tank 2 are movably connected, and the driving device 3 includes a sliding rod 306, and a slide groove 103 is provided on the adjacent surfaces of the upper and lower support rods 102. The sliding rod 306 and the slide groove 103 are slidably engaged with each other to limit the position and moving direction of the sliding rod 306. The driving device 3 also includes a motor 301 and an active rod 302. The motor 301 is fixed to the storage box On the inner side wall, one end of the active rod 302 is axially connected to the motor 301, and the other end of the active rod 302 is rotatably provided with a limit rod 303. The sliding rod 306 is fixedly connected to the end of the moving frame 304 near the motor 301. The moving frame 304 is designed as an "X" structure and has an "X"-shaped limit groove 305 formed inside. The limit rod 303 and the limit groove 305 are connected in a sliding manner. The middle section of the limit groove 305 is designed as an arc structure, and the radius is equal to the distance from the axis of the motor 301 to the axis of the limit rod 303.

[0030] like Figure 4 As shown, the transmission device 4 is arranged at the connection between the driving device 3 and the culture tank 2. The transmission device 4 includes a rack 401 and a gear 402. The rack 401 is symmetrically fixed on both sides of the sliding rod 306, and the gear 402 is fixed at the connection between the rotating rod 201 and the culture tank 2. The gear 402 and the rack 401 are in meshing transmission connection.

[0031] When in use, first turn on the heating device 5 and adjust the temperature in the storage box 1 to a suitable culture temperature under the control of the temperature sensor on the culture tank 2. Pause the heating device 5 after reaching the suitable temperature, place the fertilized egg cells of the test tube baby in the culture medium in the culture tank 2 under a sterile environment, and close the sealing door 101. Then start the motor 301 to rotate the active rod 302. Under the limit guidance of the slide groove 103 on the sliding rod 306, and the limit cooperation of the limit groove 305 and the limit rod 303, the sliding rod 306 and the rack 401 are driven to slide back and forth along the slide groove 103. Under the meshing transmission, the gear 402 and the culture tank 2 are driven to rotate back and forth, so that the outer wall of the culture tank 2 and the hot air inside the storage box 1 are fully in contact, ensuring temperature uniformity and avoiding uneven hot and cold to affect the development rate of the fertilized egg cells. At the same time, the motor 301 uses a slow motor 301 to avoid the speed block causing centrifugal damage to the fertilized egg cells.

[0032] The present invention and its embodiments are described above. This description is not restrictive. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by this and, without departing from the purpose of the present invention, designs structures and embodiments similar to this technical solution without inventiveness, they shall fall within the scope of protection of the present invention.

Claims

1. A device for assisted culture of fertilized egg cells for in vitro fertilization, comprising a storage box (1), a heating device (5) and an operating panel (6), wherein the upper portion of the storage box (1) is hinged with a sealing door (101), and a sealing rubber strip is provided at the connection, the storage box (1) is made of a heat-insulating material as a whole, and the heating device (5) is arranged inside the storage box (1), characterized in that: It also includes a culture tank (2), a driving device (3) and a transmission device (4): The culture tank (2) is rotatably arranged inside the storage box (1); Support rods (102) are fixedly provided at the upper and lower parts of the inner side of the storage box (1), and the driving device (3) is provided on the support rods (102); The driving device (3) and the culture tank (2) are movably connected, and the transmission device (4) is arranged at the connection between the driving device (3) and the culture tank (2).

2. The in vitro fertilized egg cell auxiliary culture device according to claim 1, characterized in that: A rotating rod (201) is fixedly provided at the lower end of the culture tank (2), and the rotating rod (201) is rotatably arranged at the inner bottom of the storage box (1).

3. The in vitro fertilized egg cell auxiliary culture device according to claim 2, characterized in that: The driving device (3) includes a sliding rod (306), and adjacent surfaces of the upper and lower support rods (102) are provided with sliding grooves (103), and the sliding rod (306) and the sliding grooves (103) are connected in a sliding engagement manner.

4. The in vitro fertilized egg cell auxiliary culture device according to claim 3, characterized in that: The driving device (3) further comprises a motor (301) and an active rod (302); the motor (301) is fixed to the inner side wall of the storage box (1); one end of the active rod (302) is axially connected to the motor (301); and the other end of the active rod (302) is rotatably provided with a limit rod (303).

5. The in vitro fertilized egg cell auxiliary culture device according to claim 4, characterized in that: The sliding rod (306) is fixedly connected to a moving frame (304) at one end close to the motor (301). The moving frame (304) is configured as an "X"-shaped structure and has an "X"-shaped limiting groove (305) formed therein. The limiting rod (303) and the limiting groove (305) are connected in a sliding manner.

6. The in vitro fertilized egg cell auxiliary culture device according to claim 5, characterized in that: The middle section of the limiting groove (305) is configured as an arc-shaped structure, and the radius thereof is equal to the distance from the axis of the motor (301) to the axis of the limiting rod (303).

7. The in vitro fertilized egg cell auxiliary culture device according to claim 6, characterized in that: The transmission device (4) comprises a rack (401) and a gear (402), wherein the rack (401) is symmetrically fixed on both sides of the sliding rod (306), and the gear (402) is fixed at the connection between the rotating rod (201) and the culture tank (2), and the gear (402) and the rack (401) are in meshing transmission connection.

8. The in vitro fertilized egg cell auxiliary culture device according to claim 7, characterized in that: The culture tank (2) is provided with a temperature sensor, the operation panel (6) is provided outside the storage box (1), and a control chip is provided inside.

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