Wuban pill based on non-abandoned technology and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine functional food, and discloses a spleen-invigorating pill based on a non-abandoned technology, and the spleen-invigorating pill comprises the following components in parts by weight: (1) an intestine-clearing and toxin-expelling layer: 15-25 parts of nine-steamed nine-sun-dried red dates and 3-8 parts of fructus gardeniae; (2) middle coke layer dredging: 5-10 parts of endothelium corneum gigeriae galli, 8-15 parts of hawthorn, 10-15 parts of malt, 3-6 parts of citron, 3-6 parts of fingered citron, 2-5 parts of fructus amomi and 5-10 parts of pericarpium citri reticulatae; and (4) dampness clearing and turbid layer dissolving: 10-15 parts of coix seeds, 8-12 parts of white hyacinth beans and 3-6 parts of dried ginger. According to the spleen-tonifying pill based on the non-perpetual technology and the preparation method thereof, the limitation of single qi tonifying of a traditional product is broken through, and multi-dimensional conditioning is achieved through the four-layer synergistic effect of clearing bowels and expelling toxins, dredging middle energizer to promote digestion and soothing liver, invigorating qi and blood to consolidate foundation and clearing damp and dissolving turbidity; the complex associated problems such as gastrectasia, sour regurgitation, food retention, emotional disorder, body odor, puffiness, qi and blood deficiency and liver and kidney deficiency can be solved at the same time, and both symptoms and root causes are treated.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine functional foods, and specifically relates to Guibi pills based on intangible cultural heritage technology and a preparation method thereof. Background Art

[0002] Guipi Pills are an excellent traditional Chinese medicine. They are available in several forms, including large honey pills, small honey pills, water-honey pills, and granules. They are mainly used to treat various diseases caused by deficiency of both the heart and spleen. Their effects are: invigorating qi and strengthening the spleen, nourishing blood and tranquilizing the mind. They are used for deficiency of both the heart and spleen, shortness of breath and palpitations, insomnia and dreaminess, dizziness, limb fatigue, loss of appetite, metrorrhagia and bloody stools. They can be used for constitutional deficiency, post-illness disorders, severe anemia, qi deficiency and metrorrhagia, spleen deficiency and diarrhea, and deficiency of both the heart and spleen. They have definite clinical efficacy and are widely used, making them a commonly used clinical medicine.

[0003] According to the invention patent with Chinese patent application number 201310491688.3, ​​a kind of Guipi Pills (micropills) for invigorating qi and strengthening spleen mentioned in the invention patent, the Guipi Pills (micropills) for invigorating qi and strengthening spleen adopt conventional processes (cleaning and drying) to achieve standardized production of basic medicinal materials such as Codonopsis pilosula and Atractylodes macrocephala during use. The technology is mature and the cost is controllable, and it focuses on solving the single problem of deficiency of both heart and spleen. However, the Guipi Pills (micropills) for invigorating qi and strengthening spleen lack multi-dimensional collaborative design (only invigorating qi and strengthening spleen) and in-depth processing technology, resulting in functional limitations, low drug absorption rate, narrow applicable population (such as not suitable for children / those with low sugar needs) and potential intestinal irritation.

[0004] The spleen and stomach conditioning products currently on the market and in the comparative example (201310491688.3) (such as traditional Guipi Pills and ordinary Jianpi Pills) have significant limitations:

[0005] 1. Single ingredient: Most of them are based on basic herbs such as Codonopsis pilosula and Atractylodes macrocephala, focusing on the single function of "tonifying Qi and nourishing blood", which makes it difficult to treat complex spleen and stomach problems such as food accumulation, dampness, and liver depression;

[0006] 2. Simple process: Most medicinal materials are directly used as medicine after simple cleaning and drying, lacking in-depth processing technology, resulting in weak medicinal penetration and low intestinal absorption efficiency;

[0007] 3. Narrow scope of application: It is only suitable for people with mild heart and spleen deficiency, and does not cover scenarios such as children's food accumulation, liver and kidney deficiency with spleen and stomach weakness in middle-aged and elderly people, and emotional spleen and stomach disorders;

[0008] 4. One-sided conditioning logic: lack of systematic thinking of "cleansing-unblocking-replenishing", unable to solve the chain reactions caused by spleen and stomach problems such as body odor, puffiness, qi and blood deficiency, etc.

[0009] Therefore, it is necessary to propose a Guibi Pill based on intangible cultural heritage technology and a preparation method thereof to solve the above-mentioned problems. Summary of the Invention

[0010] (1) Technical problems solved

[0011] In response to the shortcomings of the existing technology, the present invention provides a Guibi Pill based on the intangible cultural heritage process and a preparation method thereof, which has the advantages of realizing the "clearing-unblocking-tonifying" full-link conditioning through the intangible cultural heritage process (nine steaming and nine drying + 120 days of fermentation), covering a wider range of people with multi-dimensional synergistic effects, and providing the advantages of safe, efficient and symptomatic spleen and stomach care.

[0012] (2) Technical solution

[0013] To achieve the above object, the present invention provides the following technical solution: a Guipi Pill based on intangible cultural heritage technology, wherein the Guipi Pill comprises, by weight:

[0014] (1) Intestinal cleansing and detoxification layer: nine-steamed and nine-dried red dates (15-25 portions), gardenia (3-8 portions);

[0015] The nine-steaming and nine-drying red dates are pre-treated by first soaking them in plant water for 48 hours, then inoculating them with intangible cultural heritage compound probiotics (including Lactobacillus plantarum and yeast) and fermenting them for 120 days. After fermentation, they undergo nine cycles of steaming: each steaming step uses a ceramic pot with firewood heating (80-90°C for 2 hours) → natural sunlight drying (ambient humidity ≤ 40% for 48 hours). Finally, "black gold grade" red dates are obtained, and the bioavailability of their active ingredients, such as polysaccharides, is increased by more than 300% compared to traditional dried red dates.

[0016] (2) To clear the middle burner layer: Chicken gizzard lining (5-10 parts), hawthorn (8-15 parts), malt (10-15 parts), citron (3-6 parts), bergamot (3-6 parts), Amomum villosum (2-5 parts), tangerine peel (5-10 parts);

[0017] (3) Tonifying and strengthening layer: Codonopsis pilosula (10-15 parts), Astragalus membranaceus (8-12 parts), Chinese yam (10-15 parts), Poria cocos (8-12 parts), Polygonatum sibiricum (5-10 parts), Morus alba (5-10 parts), Angelica sinensis (6-9 parts), Rehmannia root (6-9 parts), Licorice root (3-6 parts);

[0018] (4) Dispelling dampness and clearing turbidity: coix seed (10-15 parts), white lentil (8-12 parts), dried ginger (3-6 parts);

[0019] (5) Auxiliary material layer: xylitol (5-10 parts), used to replace sucrose and adjust palatability.

[0020] A preparation method of Guibi Pills based on intangible cultural heritage technology, comprising the following steps:

[0021] (1) Pretreatment of key medicinal materials:

[0022] Prepare nine-steamed and nine-dried red dates according to the method of claim 1.

[0023] The tonic medicinal materials including codonopsis pilosula, astragalus root, yam, polygonatum, mulberry, angelica root, rehmannia root and liquorice are dried at low temperature (50-60°C) and then crushed into 80-100 meshes.

[0024] Chicken gizzard lining, hawthorn and other digestive herbs are soaked in rice vinegar and then roasted with vinegar.

[0025] Gardenia jasminoides, coix seed, white hyacinth bean, poria cocos, tangerine peel, citron, bergamot, amomum villosum, malt and other medicinal materials are selected, washed, dried and then crushed into 80-100 meshes.

[0026] (2) Mixing to prepare soft material: Mix all the medicinal material powders processed in step 1 with xylitol evenly, add appropriate amount of purified water, and stir to prepare a suitable soft material.

[0027] (3) Pill making: The pellets were made by extrusion method, and the pellet weight was controlled to be 0.2 g / pill.

[0028] (4) Drying: Place the wet pellets in a drying oven and dry at a low temperature of 40-50°C until the moisture content is ≤8%.

[0029] (5) Quality inspection and packaging: Quality inspection shall be carried out according to pharmacopoeia or relevant standards, and sealed packaging shall be carried out after passing the inspection.

[0030] Furthermore, during the nine-steaming and nine-drying red dates pretreatment, the intangible cultural heritage composite probiotics (including Lactobacillus plantarum and yeast) are required to be domesticated through intangible cultural heritage techniques to ensure the stability of strain activity during the fermentation process. In addition, during the nine-cycle treatment, the ceramic pot firewood heating stage strictly follows the intangible cultural heritage techniques, and the firewood is controlled to be made of jujube wood, utilizing its stable combustion characteristics to ensure heating uniformity of 50-90°C for 2 hours each time.

[0031] Furthermore, when processing the medicinal materials for the middle-jiao layer, the digestive medicinal materials such as chicken gizzard lining and hawthorn are soaked in rice vinegar, and then the vinegar-roasting preparation needs to be carried out in a traditional casserole, following the intangible cultural heritage of "alternating between gentle and strong fire" technique, first quickly heating with high fire, and then switching to low fire for slow roasting, so that the degree of vinegar roasting of the medicinal materials is uniform, thereby enhancing the digestive effect and the integration of medicinal properties.

[0032] Furthermore, in the low-temperature drying process of the tonic and strengthening medicinal materials, the "interlayer straw mat" drying method inherited from intangible cultural heritage is adopted, and a mugwort mat that has been air-dried is laid between the drying box tray and the medicinal materials. The mild properties of mugwort are used to assist in temperature control, so that the effective ingredients of tonic medicinal materials such as Codonopsis pilosula and Astragalus membranaceus are more fully retained when dried at 50-60°C, and the fineness of the powder after crushing is improved.

[0033] Furthermore, in the pill-making process, the extrusion pill-making equipment needs to use a wooden mold improved by intangible cultural heritage technology. The mold texture follows the traditional mortise and tenon joint design. In the process of controlling the pill weight to 0.2g / pill, the natural elasticity of the wooden mold is utilized to make the surface of the pill smooth and the texture uniform after forming, thereby enhancing the consistency of the appearance and internal quality of the pills.

[0034] Furthermore, in the drying step, the wet pills are placed in a drying oven and the "segmented moisture-controlled drying method" inherited from the intangible cultural heritage is adopted. They are first dried at 40°C until the moisture content is initially reduced. Then, when the temperature is raised to 50°C, bamboo charcoal bags treated with intangible cultural heritage techniques are introduced to assist in moisture absorption. The humidity environment in the drying oven is precisely controlled to ensure that the moisture content is ≤5%. During this process, the effective ingredients of the pills are not lost due to drastic changes in the drying environment.

[0035] (3) Beneficial effects

[0036] Compared with the prior art, the present invention provides a Guibi Pill based on intangible cultural heritage technology and a preparation method thereof, which has the following beneficial effects:

[0037] 1. The Guibi Pills and their preparation method, based on intangible cultural heritage technology, break through the limitation of "single Qi tonification" of traditional products and achieve multi-dimensional conditioning through the four-layer synergistic effect of "clearing the intestines and detoxifying - clearing the middle burner to digest food and soothing the liver - replenishing Qi and blood to strengthen the body - removing dampness and clearing turbidity". They can simultaneously solve complex related problems such as bloating, acid reflux, indigestion, emotional disorders, body odor, puffiness, Qi and blood deficiency, liver and kidney deficiency, etc., and treat both the symptoms and the root causes.

[0038] 2. The Guibi Pills and their preparation method based on the intangible cultural heritage technology have the advantages of unique technology and high efficiency: the core application of the intangible cultural heritage technology of "nine steaming and nine drying + 120 days of fermentation" (especially for the processing of red dates) has formed a significant technical barrier; this technology greatly improves the bioavailability of the core ingredients (more than 300%), enhances the mildness and penetration of the medicinal effect (the absorption rate is increased by 2-3 times compared with ordinary Jianpi Pills), completely removes the dryness of the medicinal materials, and achieves zero intestinal irritation.

[0039] 3. The Guibi Pills and their preparation method, which are based on intangible cultural heritage craftsmanship, have a formula design (eliminating irritating medicinal materials and using materials with medicinal and edible properties) combined with intangible cultural heritage craftsmanship to ensure mild and safe medicinal properties; xylitol replaces sucrose, adapts to low-sugar diet needs, and avoids the risk of tooth decay; the product covers a wide range of people, especially children with complex spleen and stomach problems (food accumulation), middle-aged and elderly people (deficiency with weak spleen and stomach), people with high emotional stress (liver depression and spleen deficiency), and people who need long-term health conditioning. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] Figure 1 This is a weight ratio diagram of Guibi pills of the present invention;

[0041] Figure 2 The present invention is a flow chart for preparing Guipi Pills. DETAILED DESCRIPTION

[0042] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0043] See also Figure 1 and Figure 2 , a Guipi Pill based on intangible cultural heritage technology, Guipi Pill includes, by weight:

[0044] (1) Intestinal cleansing and detoxification layer: nine-steamed and nine-dried red dates (15-25 portions), gardenia (3-8 portions);

[0045] The nine-steaming and nine-drying red dates are pre-treated: first, the red dates are soaked in plant water for 48 hours, then inoculated with intangible cultural heritage compound probiotics (including Lactobacillus plantarum and yeast) and fermented for 120 days. After fermentation, they undergo nine cycles of steaming: each steaming cycle is heated in a ceramic pot with firewood (80-90°C for 2 hours) and then air-dried in natural sunlight (ambient humidity ≤ 40% for 48 hours). The final product is the "Black Gold Grade" red dates, whose bioavailability of active ingredients such as polysaccharides is more than 300% higher than that of traditional dried red dates.

[0046] (2) To clear the middle burner layer: Chicken gizzard lining (5-10 parts), hawthorn (8-15 parts), malt (10-15 parts), citron (3-6 parts), bergamot (3-6 parts), Amomum villosum (2-5 parts), tangerine peel (5-10 parts);

[0047] (3) Tonifying and strengthening layer: Codonopsis pilosula (10-15 parts), Astragalus membranaceus (8-12 parts), Chinese yam (10-15 parts), Poria cocos (8-12 parts), Polygonatum sibiricum (5-10 parts), Morus alba (5-10 parts), Angelica sinensis (6-9 parts), Rehmannia root (6-9 parts), Licorice root (3-6 parts);

[0048] (4) Dispelling dampness and clearing turbidity: coix seed (10-15 parts), white lentil (8-12 parts), dried ginger (3-6 parts);

[0049] (5) Auxiliary material layer: xylitol (5-10 parts), used to replace sucrose and adjust palatability.

[0050] A preparation method of Guibi Pills based on intangible cultural heritage technology, comprising the following steps:

[0051] (1) Pretreatment of key medicinal materials:

[0052] Prepare nine-steamed and nine-dried red dates according to the method of claim 1.

[0053] The tonic medicinal materials including codonopsis pilosula, astragalus root, yam, polygonatum, mulberry, angelica root, rehmannia root and liquorice are dried at low temperature (50-60°C) and then crushed into 80-100 meshes.

[0054] Chicken gizzard lining, hawthorn and other digestive herbs are soaked in rice vinegar and then roasted with vinegar.

[0055] Gardenia jasminoides, coix seed, white hyacinth bean, poria cocos, tangerine peel, citron, bergamot, amomum villosum, malt and other medicinal materials are selected, washed, dried and then crushed into 80-100 meshes.

[0056] (2) Mixing to prepare soft material: Mix all the medicinal material powders processed in step 1 with xylitol evenly, add appropriate amount of purified water, and stir to prepare a suitable soft material.

[0057] (3) Pill making: The pellets were made by extrusion method, and the pellet weight was controlled to be 0.2 g / pill.

[0058] (4) Drying: Place the wet pellets in a drying oven and dry at a low temperature of 40-50°C until the moisture content is ≤8%.

[0059] (5) Quality inspection and packaging: Quality inspection shall be carried out according to pharmacopoeia or relevant standards, and sealed packaging shall be carried out after passing the inspection.

[0060] Example 1: Preparation of Guibibi Pills:

[0061] (1) Intestinal cleansing and detoxification layer: 20 portions of steamed and dried red dates, 5 portions of gardenia.

[0062] (2) To clear the middle burner layer: 8 parts of chicken gizzard lining, 12 parts of hawthorn, 12 parts of malt, 4 parts of citron, 4 parts of bergamot, 3 parts of amomum villosum, 8 parts of dried tangerine peel.

[0063] (3) Tonifying and strengthening layer: 12 parts of Codonopsis pilosula, 10 parts of Astragalus membranaceus, 12 parts of Chinese yam, 10 parts of Poria cocos, 8 parts of Polygonatum sibiricum, 8 parts of Morus alba, 7 parts of Angelica sinensis, 7 parts of Rehmannia glutinosa, and 5 parts of Licorice.

[0064] (4) Remove dampness and clear turbidity: 12 parts of coix seed, 10 parts of white lentil, 4 parts of dried ginger.

[0065] (5) Auxiliary material layer: 8 parts of xylitol.

[0066] The above-mentioned components work together to form a comprehensive "clearing-clearing-supplementing" conditioning system:

[0067] Intestinal cleansing and detoxification layer: The core ingredient, red dates, which have been fermented and steamed and dried nine times, remove intestinal dirt, eliminate dryness, and enhance permeability, while gardenia helps clear heat and purge fire.

[0068] Open the middle burner layer: Chicken gizzard lining, hawthorn, and malt work together to help digest food and eliminate accumulation; Citron and Buddha's hand soothe the liver and relieve depression; Amomum villosum and tangerine peel regulate qi and relieve fullness, solving problems such as bloating, acid reflux, and emotional disorders.

[0069] Tonifying and strengthening the foundation layer: Codonopsis pilosula, Astragalus membranaceus, Chinese yam, and Poria cocos are used to replenish qi, strengthen the spleen, and eliminate dampness; Polygonatum sibiricum and mulberry are used to replenish the liver and kidneys; Angelica sinensis and Rehmannia root nourish blood and promote blood circulation, achieving the coordinated conditioning of "spleen and stomach-qi and blood-liver and kidneys"; Licorice harmonizes all the medicines.

[0070] Eliminate dampness and turbidity: Use coix seed and white lentil to clear heat and dampness, and dried ginger to warm yang and eliminate dampness to balance the coldness, and solve puffiness and edema

[0071] Example 2: Nine-steaming and nine-drying red dates pretreatment:

[0072] 1. Take 20kg of high-quality red dates and soak them in pure plant water for 48 hours.

[0073] 2. After draining, inoculate the intangible cultural heritage composite probiotic strains (including Lactobacillus plantarum, yeast, etc.) and place it in a constant temperature (30-35°C) and constant humidity (60-70%) fermentation room for fermentation for 120 days.

[0074] 3. After fermentation is complete, perform a nine-steaming and nine-drying cycle:

[0075] Steaming: Place the fermented red dates in a traditional ceramic pot, heat with pine wood fire, maintain the temperature at 85±5℃, and steam for 2 hours.

[0076] Drying: Spread the steamed red dates evenly and dry them in natural sunlight. Choose a sunny day with an ambient humidity of ≤40% and dry them for 48 hours.

[0077] Repeat the above steaming and drying steps for a total of 9 rounds.

[0078] 4. The "Black Gold Grade" nine-steamed and nine-dried red dates with a dark brown to black color were obtained. The polysaccharide content and solubility were tested, and the bioavailability was significantly improved.

[0079] Example 3: Preparation of Guibibi Pills:

[0080] 1. Prepare nine-steamed and nine-dried red dates according to the method of Example 2.

[0081] 2. Wash Codonopsis pilosula, Astragalus membranaceus, Chinese yam, Polygonatum sibiricum, mulberry, Chinese angelica, Rehmannia root and liquorice, dry them at 50-60℃, and grind them through a 100-mesh sieve.

[0082] 3. After cleaning the chicken gizzard lining and hawthorn, mix them with rice vinegar and moisten them. Stir-fry over low heat until they are slightly dry and puffed up. After cooling, crush them and pass through a 100-mesh sieve.

[0083] 4. Select, wash, dry, and grind gardenia, coix seed, white hyacinth bean, poria, tangerine peel, citron, bergamot, amomum villosum, and malt through a 100-mesh sieve.

[0084] 5. Grind the steamed and dried red dates through an 80-mesh sieve (due to their special texture).

[0085] 6. Mix all the medicinal material powders obtained in steps 2, 3, 4, and 5 with xylitol thoroughly.

[0086] 7. Add appropriate amount of purified water to the mixed powder, stirring while adding to make a soft material with moderate hardness.

[0087] 8. Use a pellet making machine (such as the ZL-30 extrusion pellet making machine) to make wet pellets with a diameter of about 3-4 mm and a pellet weight of 0.2 g.

[0088] 9. Spread the wet pills evenly on a drying tray and dry them in a drying oven at 45±5℃ until the moisture content is ≤8% (about 6-8 hours).

[0089] 10. Sieve the dried pills to separate the whole pills and remove the irregularly shaped pills. Then inspect the appearance, moisture, weight difference, microbial limit, etc. according to the requirements of the pharmacopoeia.

[0090] 11. Qualified pills are sealed and packaged in aluminum-plastic blisters or bottles.

[0091] In summary, the Guibi Pills and their preparation method based on intangible cultural heritage technology break through the limitation of "single qi tonification" of traditional products, and achieve multi-dimensional conditioning through the four-layer synergistic effect of "clearing the intestines and detoxifying - clearing the middle burner to digest food and soothing the liver - replenishing qi and blood to strengthen the foundation - removing dampness and clearing turbidity". It can simultaneously solve complex related problems such as bloating, acid reflux, indigestion, emotional disorders, body odor, puffiness, qi and blood deficiency, liver and kidney deficiency, etc., and treat both the symptoms and the root causes.

[0092] In addition, the uniqueness and high efficiency of the process: the core application of the "nine steaming and nine drying + 120 days of fermentation" intangible cultural heritage process (especially for the processing of red dates) has formed a significant technical barrier; this process greatly improves the bioavailability of core ingredients (more than 300%), enhances the mildness and penetration of the medicinal effect (the absorption rate is 2-3 times higher than that of ordinary spleen-strengthening pills), completely removes the dryness of the medicinal materials, and achieves zero intestinal irritation.

[0093] In addition, the formula design (eliminating irritating medicinal materials and using materials with medicinal and edible properties) is combined with intangible cultural heritage craftsmanship to ensure that the medicinal properties are mild and safe; xylitol replaces sucrose, adapts to low-sugar diet needs, and avoids the risk of tooth decay; the product covers a wide range of people, especially suitable for children with complex spleen and stomach problems (food accumulation), middle-aged and elderly people (deficiency with weak spleen and stomach), people with high emotional stress (liver depression and spleen deficiency) and people who need long-term health conditioning.

[0094] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply the existence of any such actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or device comprising the element.

[0095] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A Guibi pill based on intangible cultural heritage technology, characterized in that: The Guipi Pills comprise, by weight: (1) Intestinal cleansing and detoxification layer: nine-steamed and nine-dried red dates (15-25 portions), gardenia (3-8 portions); The nine-steaming and nine-drying red dates are pre-treated by first soaking them in plant water for 48 hours, then inoculating them with intangible cultural heritage compound probiotics (including Lactobacillus plantarum and yeast) and fermenting them for 120 days. After fermentation, they undergo nine cycles of steaming: each steaming step uses a ceramic pot with firewood heating (80-90°C for 2 hours) → natural sunlight drying (ambient humidity ≤ 40% for 48 hours). Finally, "black gold grade" red dates are obtained, and the bioavailability of their active ingredients, such as polysaccharides, is increased by more than 300% compared to traditional dried red dates. (2) To clear the middle burner layer: Chicken gizzard lining (5-10 parts), hawthorn (8-15 parts), malt (10-15 parts), citron (3-6 parts), bergamot (3-6 parts), Amomum villosum (2-5 parts), tangerine peel (5-10 parts); (3) Tonifying and strengthening layer: Codonopsis pilosula (10-15 parts), Astragalus membranaceus (8-12 parts), Chinese yam (10-15 parts), Poria cocos (8-12 parts), Polygonatum sibiricum (5-10 parts), Morus alba (5-10 parts), Angelica sinensis (6-9 parts), Rehmannia root (6-9 parts), Licorice root (3-6 parts); (4) Dispelling dampness and clearing turbidity: coix seed (10-15 parts), white lentil (8-12 parts), dried ginger (3-6 parts); (5) Auxiliary material layer: xylitol (5-10 parts), used to replace sucrose and adjust palatability.

2. A method for preparing Guibi Pills based on intangible cultural heritage technology, characterized in that: The following steps are involved: (1) Pretreatment of key medicinal materials: Prepare nine-steamed and nine-dried red dates according to the method of claim 1. The tonic medicinal materials including codonopsis pilosula, astragalus root, yam, polygonatum, mulberry, angelica root, rehmannia root and liquorice are dried at low temperature (50-60°C) and then crushed into 80-100 meshes. Chicken gizzard lining, hawthorn and other digestive herbs are soaked in rice vinegar and then roasted with vinegar. Gardenia jasminoides, coix seed, white hyacinth bean, poria cocos, tangerine peel, citron, bergamot, amomum villosum, malt and other medicinal materials are selected, washed, dried and then crushed into 80-100 meshes. (2) Mixing to prepare soft material: Mix all the medicinal material powders processed in step 1 with xylitol evenly, add appropriate amount of purified water, and stir to prepare a suitable soft material. (3) Pill making: The pellets were made by extrusion method, and the pellet weight was controlled to be 0.2 g / pill. (4) Drying: Place the wet pellets in a drying oven and dry at a low temperature of 40-50°C until the moisture content is ≤8%. (5) Quality inspection and packaging: Quality inspection shall be carried out according to pharmacopoeia or relevant standards, and sealed packaging shall be carried out after passing the inspection.

3. The method for preparing Guibi Pills based on intangible cultural heritage technology according to claim 2, characterized in that: During the nine-steaming and nine-drying red dates pretreatment, the intangible cultural heritage composite probiotics (including Lactobacillus plantarum and yeast) are required to be domesticated using intangible cultural heritage techniques to ensure stable strain activity during the fermentation process. In addition, during the nine-cycle treatment, the ceramic pot firewood heating stage strictly follows the intangible cultural heritage techniques, and the firewood is controlled to be made of jujube wood, utilizing its stable combustion characteristics to ensure uniform heating at 50-90°C for 2 hours each time.

4. The method for preparing Guibi Pills based on intangible cultural heritage technology according to claim 2, characterized in that: When processing the medicinal materials for the middle-jiao layer, the digestive medicinal materials such as chicken gizzard lining and hawthorn are soaked in rice vinegar, and then the vinegar-roasting preparation needs to be carried out in a traditional casserole, following the intangible cultural heritage of "alternating between gentle and strong fire" technique, first quickly heating with high heat, and then switching to low heat for slow roasting, so that the degree of vinegar roasting of the medicinal materials is uniform, thereby enhancing the digestive effect and the integration of medicinal properties.

5. The method for preparing Guibi Pills based on intangible cultural heritage technology according to claim 2, characterized in that: The low-temperature drying process of the tonic and strengthening medicinal materials adopts the intangible cultural heritage "interlayer straw mat" drying method, laying a sun-dried mugwort mat between the drying box tray and the medicinal materials, and using the mild properties of mugwort to assist in temperature control, so that the effective ingredients of tonic medicinal materials such as Codonopsis pilosula and Astragalus membranaceus are more fully retained when dried at 50-60℃, and the fineness of the powder after crushing is improved.

6. The method for preparing Guibi Pills based on intangible cultural heritage technology according to claim 2, characterized in that: In the pill-making process, the extrusion pill-making equipment needs to use a wooden mold improved by intangible cultural heritage technology. The texture of the mold follows the traditional mortise and tenon joint design. In the process of controlling the pill weight to 0.2g / pill, the natural elasticity of the wooden mold is used to make the surface of the pill smooth and the texture uniform after forming, thereby enhancing the consistency of the appearance and internal quality of the pills.

7. The method for preparing Guibi Pills based on intangible cultural heritage technology according to claim 2, characterized in that: In the drying process, the wet pills are placed in a drying oven and the "segmented moisture-controlled drying method" inherited from the intangible cultural heritage is adopted. They are first dried at a low humidity of 40°C until the moisture content is initially reduced. Then, when the temperature is raised to 50°C, bamboo charcoal bags treated with intangible cultural heritage techniques are introduced to assist in moisture absorption. The humidity environment in the drying oven is precisely controlled to ensure that the moisture content is ≤5%. During this process, the effective ingredients of the pills are not lost due to drastic changes in the drying environment.

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