A disinfection device for biopharmaceutical preparation based on high-temperature steam

Abstract

This invention relates to the field of disinfection device technology and discloses a disinfection device for biopharmaceutical preparation based on high-temperature steam. The device includes a disinfection box, a side box, and a disinfection cylinder. The disinfection cylinder contains a steam output component, a storage component, and a guide component. The side box contains a drive component. The steam output component, with its annular multi-hole steam jet, works in conjunction with a rotatable multi-layered hollow storage component to achieve multi-directional and uniform steam injection and full exposure of all surfaces of the items, eliminating disinfection blind spots. The guide component and drive component work together, controlling the airflow direction through the rotation of the conical shell, enhancing turbulence and steam penetration. The overall technical solution effectively solves the problems of uneven steam distribution and poor penetration affecting the disinfection effect of traditional disinfection devices, significantly improving disinfection efficiency and temperature uniformity, and ensuring the disinfection quality in the biopharmaceutical preparation process.

Description

Technical Field

[0001] This invention relates to the field of disinfection equipment technology, and in particular to a disinfection equipment for biopharmaceutical preparation based on high-temperature steam. Background Technology

[0002] In the field of biopharmaceutical preparation, a sterile environment is crucial. Traditional disinfection methods, such as chemical disinfection, are prone to leaving harmful residues that affect drug quality. While dry heat disinfection can kill some microorganisms, it is not very effective for disinfecting complex equipment. High-temperature steam disinfection has become the mainstream method because it can destroy the cell structure and proteins of microorganisms by using high temperatures. However, existing high-temperature steam disinfection devices for biopharmaceutical preparation have problems such as uneven steam distribution and condensate accumulation that affects the disinfection effect, which urgently need to be improved.

[0003] A Chinese patent with publication number CN118059274B discloses an automatic disinfection device based on fiber fabric recycling. This invention combines multiple disinfection methods and utilizes the cooperation of an integral part and independent parts to achieve continuous dynamic disinfection of the fabric. It can complete continuous and efficient disinfection of multiple areas or multiple fabrics in a single area in a single operation. At the same time, during the exchange of different disinfection methods, the fabric is kept in a non-absorption saturation state to receive disinfection, thereby enabling the fabric to be disinfected quickly and thoroughly. This ensures that a single disinfection method achieves an effective effect on the fabric while improving the overall disinfection effect of multiple disinfection methods combined on the fabric.

[0004] Regarding the above and existing related technologies, the inventors believe that the following defects often exist: Existing disinfection devices often use single-sided or local single-point spraying for steam injection, resulting in uneven steam distribution and disinfection blind spots. In addition, the carrier structure is often a fixed single-layer or a multi-layer structure with insufficient perforation and small interlayer spacing, lacking adjustment function, making it difficult for part of the surface of the item to be fully exposed to the steam, thus affecting the disinfection effect. Summary of the Invention

[0005] The technical problem to be solved by the present invention is that the existing technology of steam sterilization has poor penetration and is not convenient for uniform sterilization from multiple angles. To this end, we propose a sterilization device for biopharmaceutical preparation based on high-temperature steam.

[0006] To achieve the above objectives, this application adopts the following technical solution: a sterilization device for biopharmaceutical preparation based on high-temperature steam, including a sterilization box, a side box fixedly installed on one side of the sterilization box, a sterilization cylinder inside the sterilization box, a steam output component for supplying gas inside the sterilization cylinder, a storage component for placing medicine inside the sterilization cylinder, a driving component inside the side box, and a guide component for controlling airflow backflow inside the storage component;

[0007] The storage component includes a mounting ring installed inside the disinfection cylinder. An inner plate is fixedly connected to the inner wall of the mounting ring. An installation groove is opened on the surface of the inner plate. A hollow box for holding medicine is installed inside the installation groove. A base plate is also fixedly connected to the inner wall of the mounting ring. A ventilation groove is formed between the inner plate and the base plate and is connected to the corresponding installation groove of the hollow box. A support ring is fixedly connected to the upper surface of the base plate. The support ring is set correspondingly to the hollow box. A first ventilation groove is opened at the center of the upper surface of both the inner plate and the base plate.

[0008] Preferably, the guide component includes a long rod rotatably connected inside the chassis, a conical shell fixedly connected to one end of the long rod, the conical shell being correspondingly arranged with the first ventilation groove, an internal gear fixedly connected to the other end of the long rod, a connecting ring fixedly connected to the inner wall of the disinfection cylinder, a connecting block fixedly connected to the inner wall of the connecting ring, a rack plate fixedly connected to the upper surface of the connecting block, and the rack plate meshing with the internal gear.

[0009] Preferably, the drive component includes a motor disposed inside the side box, a rotating shaft fixedly connected to the output end of the motor, a drive gear fixedly connected to the outside of the rotating shaft, and an external gear ring fixedly connected to the outside of the mounting ring, the external gear ring meshing with the drive gear.

[0010] Preferably, there are two sets of storage components and drive gears. The two sets of storage components and drive gears are vertically distributed and the drive gears are correspondingly arranged with the storage components. A second ventilation groove is opened on the upper surface of the inner disk. The second ventilation groove located above is correspondingly arranged with the hollow box located below. The two sets of conical shells are in opposite rotation states.

[0011] Preferably, a cube is fixedly connected to one side of the internal gear, and a groove is provided on the inner wall of the chassis. The cube is slidably connected inside the groove, and a flip groove is also provided on the inner wall of the groove. The flip groove is correspondingly set with the connecting block.

[0012] Preferably, a short rod is fixedly connected to the side of the conical shell opposite to the long rod, and the short rod is rotatably connected to the inside of the chassis.

[0013] Preferably, a drain groove is provided on the upper surface of the chassis, the drain groove is located inside the support ring, and a guide ring is fixedly connected to one side of the connecting block. The guide ring is arranged corresponding to the bottom opening of the drain groove, and the guide ring is a circular ring with an flared bottom.

[0014] Preferably, a sealing groove is provided on the upper surface of the mounting ring, and the sealing groove is slidably connected to the disinfection cylinder.

[0015] Preferably, the steam output component includes an air supply pipe fixedly connected to one side of the disinfection box, one end of the air supply pipe passing through the disinfection box and the disinfection cylinder and fixedly connected to an air supply ring, an air supply ring fixedly installed on the bottom surface of the air supply ring, an air jet pipe fixedly connected to the bottom surface of the air supply ring, and an exhaust pipe and a safety valve provided at the bottom of the disinfection box.

[0016] Preferably, the bottom of the disinfection cylinder is provided with a draining component for draining condensate. The draining component includes a concave draining tray fixedly connected to the bottom surface of the disinfection cylinder, a draining pipe fixedly connected to the bottom surface of the concave draining tray, and a drain valve provided inside the draining pipe.

[0017] The technical effects and advantages of this invention are as follows:

[0018] In this invention, during disinfection, the annular multi-hole steam jet steam output component, in conjunction with the rotatable multi-layer hollowed-out storage component, achieves multi-directional uniform steam injection and full exposure of all surfaces of the item, eliminating disinfection blind spots. The guiding component and the driving component work together, controlling the airflow direction through the flipping of the conical shell, enhancing turbulence and steam penetration. The overall technical solution effectively solves the problems of uneven steam distribution and poor penetration affecting the disinfection effect of traditional disinfection devices, greatly improving disinfection efficiency and temperature uniformity, and ensuring the disinfection quality in the biopharmaceutical preparation process. Attached Figure Description

[0019] The disclosure of this invention is illustrated with reference to the accompanying drawings. It should be understood that the drawings are for illustrative purposes only and are not intended to limit the scope of protection of this invention. In the drawings, the same reference numerals are used to refer to the same parts:

[0020] Figure 1 This is a schematic diagram of the overall structure of the device of the present invention;

[0021] Figure 2 This is a schematic diagram of the internal structure of the disinfection box of the present invention;

[0022] Figure 3 This is a schematic diagram of the drive component and steam output component of the present invention;

[0023] Figure 4 This is a schematic diagram of the internal structure of the bottom frame of the present invention;

[0024] Figure 5 This is a schematic diagram of the chassis, support ring, and drainage trough structure of the present invention;

[0025] Figure 6 This is a schematic diagram of the connecting ring structure of the present invention;

[0026] Figure 7 This is a schematic diagram of the guide component structure of the present invention;

[0027] Figure 8 This is a schematic diagram of the drainage component structure of the present invention;

[0028] Figure 9 This is a schematic diagram of the internal structure of the chassis of the present invention.

[0029] Legend: 1. Disinfection box; 11. Side box; 12. Disinfection cylinder; 2. Drive component; 21. Motor; 22. Shaft; 23. Drive gear; 24. External gear ring; 3. Steam output component; 31. Gas supply pipe; 32. Gas supply ring; 33. Jet pipe; 4. Storage component; 41. Mounting ring; 411. Sealing groove; 42. Inner plate; 421. Second vent groove; 422. First vent groove; 43. 44. Hollow box; 45. Support ring; 46. Chassis; 47. Slide groove; 48. Tilting groove; 49. Drainage groove; 40. Connecting ring; 41. Guide ring; 52. Guide component; 53. Connecting block; 54. Rack plate; 55. Internal gear; 66. Cube block; 77. Long rod; 88. Conical shell; 99. Short rod; 10. Drainage component; 11. Concave drainage tray; 12. Drainage pipe; 13. Steam trap. Detailed Implementation

[0030] It is readily understood that, based on the technical solution of this invention, those skilled in the art can propose various interchangeable structural methods and implementations without altering the essential spirit of the invention. Therefore, the following detailed embodiments and accompanying drawings are merely illustrative examples of the technical solution of this invention and should not be considered as the entirety of the invention or as limitations or restrictions on the technical solution of this invention.

[0031] Reference Figures 1-5 As shown, the present invention provides a technical solution: a sterilization device for biopharmaceutical preparation based on high-temperature steam, including a sterilization box 1, a side box 11 fixedly installed on one side of the sterilization box 1, a sterilization cylinder 12 disposed inside the sterilization box 1, a steam output component 3 for supplying gas disposed inside the sterilization cylinder 12, a storage component 4 for placing medicine disposed inside the sterilization cylinder 12, a driving component 2 disposed inside the side box 11, and a guide component 5 for controlling airflow backflow disposed inside the storage component 4;

[0032] The storage component 4 includes an installation ring 41 disposed inside the disinfection cylinder 12. An inner plate 42 is fixedly connected to the inner wall of the installation ring 41. An installation groove is opened on the surface of the inner plate 42. A hollow box 43 for holding medicine is disposed inside the installation groove. A base plate 45 is also fixedly connected to the inner wall of the installation ring 41. A ventilation groove is formed between the inner plate 42 and the base plate 45 and is connected to the corresponding installation groove of the hollow box 43. A support ring 44 is fixedly connected to the upper surface of the base plate 45. The support ring 44 is correspondingly disposed to the hollow box 43. A first ventilation groove 422 is opened at the center of the upper surface of both the inner plate 42 and the base plate 45. During the disinfection process, high-temperature steam is introduced into the disinfection box 1 from the top to disinfect the medicine inside the hollow box 43. The high-temperature steam can pass through the first ventilation groove 422 and the installation groove to continue to flow downward. The support ring 44 supports the hollow box 43 from the bottom.

[0033] Reference Figures 1-9As shown in this embodiment: the guide component 5 includes a long rod 54 rotatably connected inside the chassis 45. One end of the long rod 54 is fixedly connected to a conical shell 55, which is correspondingly arranged with the first ventilation groove 422. The other end of the long rod 54 is fixedly connected to an internal gear 53. A connecting ring 47 is fixedly connected to the inner wall of the disinfection cylinder 12. A connecting block 51 is fixedly connected to the inner wall of the connecting ring 47. A rack plate 52 is fixedly connected to the upper surface of the connecting block 51. The rack plate 52 meshes with the internal gear 53. During the downward discharge of steam, some steam is discharged downward through the first ventilation groove 422. The steam flow inside the first ventilation groove 422 is discharged into the ventilation grooves around it under the guidance of the conical shell 55. Under the guidance of the support ring 44, it is discharged in the opposite direction from the mounting groove, backflushing the medicine in the hollow box 43, thereby enhancing the airflow turbulence and steam penetration.

[0034] The driving component 2 includes a motor 21 installed inside the side box 11. A rotating shaft 22 is fixedly connected to the output end of the motor 21. A drive gear 23 is fixedly connected to the outside of the rotating shaft 22. An external gear ring 24 is fixedly connected to the outside of the mounting ring 41. The external gear ring 24 meshes with the drive gear 23. During the disinfection process, the motor 21 drives the rotating shaft 22 and the drive gear 23 to rotate, thereby driving the external gear ring 24 to rotate. The mounting ring 41 rotates accordingly, allowing the steam airflow above to be evenly injected into the hollow box 43 from multiple directions. During the rotation, the internal gear 53 moves and meshes with the rack plate 52, thereby driving the internal gear 53 to rotate half a turn, thus realizing the flipping of the conical shell 55. When the conical shell 55 flips, the airflow is discharged through the conical shell 55 at this time, achieving convergence and discharge, thereby enhancing the airflow.

[0035] Two sets of storage components 4 and drive gears 23 are provided. The two sets of storage components 4 and drive gears 23 are vertically distributed and the drive gears 23 are corresponding to the storage components 4. A second ventilation groove 421 is provided on the upper surface of the inner plate 42. The second ventilation groove 421 located above corresponds to the hollow box 43 located below. The two sets of conical shells 55 rotate in opposite directions. During the downward discharge of steam, air can be blown into the hollow box 43 below through the second ventilation groove 421 to ensure the disinfection effect. At the same time, the two sets of conical shells 55 always rotate in opposite directions, so that when the airflow discharged from the upper conical shell 55 is enhanced, the corresponding steam airflow rushes towards the surface of the conical shell 55 and then diffuses to the surroundings for backflow.

[0036] A cube 531 is fixedly connected to one side of the internal gear 53. A groove 451 is provided on the inner wall of the chassis 45. The cube 531 is slidably connected inside the groove 451. A flip groove 452 is also provided on the inner wall of the groove 451. The flip groove 452 is correspondingly set with the connecting block 51. During the normal rotation of the mounting ring 41, the cube 531 always slides inside the groove 451, which has a limiting effect and prevents the conical shell 55 from flipping. When the internal gear 53 contacts the rack plate 52, the cube 531 flips in the flip groove 452 and then enters the groove 451 again and continues to slide.

[0037] A short rod 56 is fixedly connected to the side of the conical shell 55 opposite to the long rod 54. The short rod 56 is rotatably connected to the inside of the chassis 45. The short rod 56 further ensures the stability of the conical shell 55 when it is turned over.

[0038] A drain groove 46 is provided on the upper surface of the chassis 45. The drain groove 46 is located inside the support ring 44. A guide ring 471 is fixedly connected to one side of the connecting block 51. The guide ring 471 is set corresponding to the bottom opening of the drain groove 46. The guide ring 471 is a circular ring with an flared bottom. When the airflow enters the ventilation groove and is discharged to the support ring 44, the condensate in the ventilation groove is blown towards the drain groove 46. Under the action of the closed drain groove 46 and the centrifugal force of the rotating chassis 45, the condensate is discharged through the drain groove 46 and discharged to the surroundings under the guidance of the connecting ring 47, thereby preventing the condensate from dripping directly downwards and affecting the disinfection of the drug.

[0039] A sealing groove 411 is provided on the upper surface of the mounting ring 41. The sealing groove 411 is slidably connected to the disinfection cylinder 12. The sealing groove 411 ensures the sealing effect while ensuring the normal sliding of the mounting ring 41.

[0040] The steam output component 3 includes an air supply pipe 31 fixedly connected to one side of the disinfection box 1. One end of the air supply pipe 31 passes through the disinfection box 1 and the disinfection cylinder 12 and is fixedly connected to an air supply ring 32. An air supply ring 32 is fixedly installed on the bottom surface of the air supply ring 32, and an air jet pipe 33 is fixedly connected to the bottom surface of the air supply ring 32. An exhaust pipe and a safety valve are provided at the bottom of the disinfection box 1. High-temperature steam is sprayed downward from the air supply ring 32 and the air jet pipe 33 through the air supply pipe 31 to provide high-temperature steam moving downward for disinfection.

[0041] The bottom of the disinfection cylinder 12 is provided with a drain component 6 for draining condensate. The drain component 6 includes a concave drain pan 61 fixedly connected to the bottom surface of the disinfection cylinder 12. A drain pipe 62 is fixedly connected to the bottom surface of the concave drain pan 61. A drain valve 63 is provided inside the drain pipe 62. The concave drain pan 61, the drain pipe 62 and the drain valve 63 facilitate the drainage of condensate.

[0042] Working principle: Before disinfection, the medicine is placed inside 43. After closing 1, the external steam generator is turned on. High-temperature steam is sprayed downward from the air supply ring 32 and the jet pipe 33 through the air supply pipe 31 to disinfect the medicine inside the hollow box 43. The high-temperature steam can pass through the first ventilation groove 422, the second ventilation groove 421 and the installation groove to continue to flow downward. Some of the steam passes through the space between the first ventilation grooves 422 and enters the interior of the first ventilation groove 422. Under the guidance of the conical shell 55, the steam airflow is discharged to the ventilation grooves around it. Under the guidance of the support ring 44, it is discharged in the opposite direction from the installation groove, backflushing the medicine inside the hollow box 43, thereby enhancing the airflow turbulence and steam penetration.

[0043] In addition, during the disinfection process, the motor 21 drives the rotating shaft 22 and the drive gear 23 to rotate, thereby driving the outer gear ring 24 to rotate. The mounting ring 41 rotates accordingly, allowing the steam airflow above to be evenly injected into the hollow box 43 from multiple directions. During the rotation, the inner gear 53 moves and meshes with the rack plate 52, thereby driving the inner gear 53 to rotate half a turn, thus realizing the flipping of the conical shell 55. When the conical shell 55 flips, the airflow is discharged through the conical shell 55 at this time, realizing the convergence and enhanced airflow. When the airflow discharged from the upper conical shell 55 is enhanced, the corresponding steam airflow rushes towards the surface of the conical shell 55, thereby spreading outwards to backflush, ensuring the backflush effect of the airflow below.

[0044] When the airflow enters the ventilation groove and is discharged towards the support ring 44, the condensate inside the ventilation groove is blown towards the drain groove 46. Under the action of the centrifugal force of the rotating chassis 45 and the sealing of the drain groove 46, the condensate is discharged through the drain groove 46 and discharged to the surroundings under the guidance of the connecting ring 47, thereby preventing the condensate from dripping directly downwards and affecting the disinfection of the drug. Through the setting of the concave drain plate 61, drain pipe 62 and drain valve 63, the condensate is finally discharged to prevent excessive condensate residue, which would lead to poor temperature uniformity.

[0045] The technical scope of this invention is not limited to the content described above. Those skilled in the art can make various modifications and variations to the above embodiments without departing from the technical concept of this invention, and all such modifications and variations should fall within the protection scope of this invention.

Claims

1. A disinfection device for biopharmaceutical preparation based on high-temperature steam, characterized in that, The device includes a disinfection box, a side box fixedly installed on one side of the disinfection box, a disinfection cylinder inside the disinfection box, a steam output component for supplying gas inside the disinfection cylinder, a storage component for placing medicine inside the disinfection cylinder, a driving component inside the side box, and a guide component for controlling airflow backflow inside the storage component. The storage component includes an installation ring disposed inside the disinfection cylinder. An inner plate is fixedly connected to the inner wall of the installation ring. An installation groove is formed on the surface of the inner plate. A hollow box for holding medicine is disposed inside the installation groove. A base plate is also fixedly connected to the inner wall of the installation ring. A ventilation groove is formed between the inner plate and the base plate and is connected to the installation groove corresponding to the hollow box. A support ring is fixedly connected to the upper surface of the base plate. The support ring is correspondingly disposed to the hollow box. A first ventilation groove is formed at the center of the upper surface of both the inner plate and the base plate. The guide component includes a long rod rotatably connected inside the chassis. One end of the long rod is fixedly connected to a conical shell, which is correspondingly arranged with the first ventilation slot. The other end of the long rod is fixedly connected to an internal gear. A connecting ring is fixedly connected to the inner wall of the disinfection cylinder. A connecting block is fixedly connected to the inner wall of the connecting ring. A rack plate is fixedly connected to the upper surface of the connecting block, and the rack plate meshes with the internal gear. The driving component includes a motor disposed inside the side box, a rotating shaft fixedly connected to the output end of the motor, a driving gear fixedly connected to the outside of the rotating shaft, and an external gear ring fixedly connected to the outside of the mounting ring, the external gear ring meshing with the driving gear. The storage component and the drive gear are provided in two sets. The two sets of storage components and drive gears are vertically distributed and the drive gears are correspondingly arranged with the storage components. A second ventilation groove is opened on the upper surface of the inner plate. The second ventilation groove located above is correspondingly arranged with the hollow box located below. The two sets of conical shells are in opposite rotation states.

2. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 1, characterized in that: A cube is fixedly connected to one side of the internal gear. A sliding groove is provided on the inner wall of the chassis. The cube is slidably connected to the inside of the sliding groove. A flip groove is also provided on the inner wall of the sliding groove. The flip groove is correspondingly set with the connecting block.

3. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 2, characterized in that: A short rod is fixedly connected to the side of the conical shell opposite to the long rod, and the short rod is rotatably connected to the inside of the chassis.

4. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 2, characterized in that: A drainage groove is provided on the upper surface of the chassis. The drainage groove is located inside the support ring. A guide ring is fixedly connected to one side of the connecting block. The guide ring is arranged corresponding to the bottom opening of the drainage groove. The guide ring is a circular ring with an flared bottom.

5. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 1, characterized in that: A sealing groove is provided on the upper surface of the mounting ring, and the sealing groove is slidably connected to the disinfection cylinder.

6. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 1, characterized in that: The steam output component includes an air supply pipe fixedly connected to one side of the disinfection box. One end of the air supply pipe passes through the disinfection box and the disinfection cylinder and is fixedly connected to an air supply ring. An air supply ring is fixedly installed on the bottom surface of the air supply ring, and an air jet pipe is fixedly connected to the bottom surface of the air supply ring. An exhaust pipe and a safety valve are provided at the bottom of the disinfection box.

7. The disinfection device for biopharmaceutical preparation based on high-temperature steam according to claim 6, characterized in that: The bottom of the disinfection cylinder is provided with a draining component for draining condensate. The draining component includes a concave draining plate fixedly connected to the bottom surface of the disinfection cylinder. A draining pipe is fixedly connected to the bottom surface of the concave draining plate, and a drain valve is provided inside the draining pipe.

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