Sample cup separation device and method

Abstract

The invention discloses a sample cup dividing device and method, and relates to the technical field of sample analysis, for the sample cup dividing device, a tube supply mechanism of a tube supply module is used for receiving and transmitting sub-sample tubes, and a placement mechanism is used for placing the sub-sample tubes at designated positions; a labeling mechanism of the labeling module is used for pasting bar code labels to the sub-sample tubes, and a bar code reader is used for verifying information of the bar code labels; a sample introduction rail of the rail module is used for receiving a mother sample tube, a mother sample rail is used for conveying the mother sample tube to the dispensing module, and a sub-sample rail is used for conveying a sub-sample tube to the dispensing module; a dispensing manipulator of the dispensing module can automatically prick a dispensing head from a dispensing head supply device, suck a sample from a mother sample tube through the dispensing head and dispense the sample into one or more sub-sample tubes. According to the sample cup dividing device, the problems that in the prior art, manual operation is tedious, efficiency is low, cross contamination is prone to occurring, and label pasting is not standard are solved, and the sample processing efficiency and accuracy are remarkably improved.

Description

Technical Field

[0001] The present application relates to the technical field of sample analysis, and in particular to a sample cupping device and method. Background Art

[0002] In laboratory automation systems, testing typically involves a single sample tube to reduce sample volume and alleviate the pain experienced by patients during the sampling process. However, when a sample is required for multiple tests, multiple instruments must use the same sample. In this scenario, traditional sample processing methods struggle to meet the demands of high-throughput testing and also fail to effectively address sample packaging and labeling management.

[0003] Traditionally, sample aliquoting has been performed manually or through semi-automatic pipetting. This method is not only cumbersome, inefficient, and costly, but also prone to cross-contamination, affecting the accuracy of test results. Furthermore, manual labeling of sample tubes often results in poorly labeled information, making it difficult to identify and causing significant inconvenience to laboratory work. Summary of the Invention

[0004] The purpose of this application is to provide a sample dispensing device that achieves automatic supply, labeling, efficient transfer, and precise dispensing of sample tubes. This effectively solves the problems of cumbersome manual operation, low efficiency, cross-contamination, and irregular labeling in traditional technologies, significantly improving sample processing efficiency and accuracy. Another purpose of this application is to provide a sample dispensing method.

[0005] To achieve the above objectives, the present application provides a sample cupping device, comprising:

[0006] a tube supply module, configured to supply sub-sample tubes, the tube supply module comprising a tube supply mechanism and a placement mechanism, the tube supply mechanism being configured to receive and transfer the sub-sample tubes, and the placement mechanism being configured to place the sub-sample tubes at designated locations;

[0007] a labeling module for automatically attaching labels to the sub-sample tubes, the labeling module comprising a labeling mechanism and a barcode reader, the labeling mechanism for attaching barcode labels to the sub-sample tubes, and the barcode reader for verifying the barcode label information;

[0008] A track module is used to transport the mother sample tube and the daughter sample tube. The track module includes an injection track, a mother sample track, and a daughter sample track. The injection track is used to receive the mother sample tube, the mother sample track is used to transport the mother sample tube to the dispensing module, and the daughter sample track is used to transport the daughter sample tube to the dispensing module.

[0009] The dispensing module is used to dispense the sample in the mother sample tube into the sub-sample tube. The dispensing module includes a dispensing head supply device and a dispensing robot. The dispensing robot can automatically pick up the dispensing head from the dispensing head supply device, and use the dispensing head to absorb the sample from the mother sample tube and dispense it into one or more sub-sample tubes.

[0010] In some embodiments, the tube supply mechanism includes a hopper, a discharge port, a lifting mechanism and a discharge detection assembly. The hopper is used to receive bulk sub-sample tubes, the discharge port is used to output the sub-sample tubes one by one, the lifting mechanism is used to lift the sub-sample tubes from the hopper to the discharge port, and the discharge detection assembly is used to detect the orientation of the sub-sample tubes and send adjustment instructions to the placement mechanism, and the placement mechanism adjusts the orientation of the sub-sample tubes to a consistent direction.

[0011] In some embodiments, the placement mechanism includes a clamping assembly and a motion assembly, the clamping assembly is used to clamp the sub-sample tube, and the motion assembly is used to rotate and move the sub-sample tube; the rotation operation includes adjusting the orientation of the sub-sample tube and rotating the horizontal sub-sample tube to an upright state, and the movement operation is used to send the sub-sample tube to a designated position of the labeling module.

[0012] In some embodiments, the labeling module further includes a rotating disk, which is rotatable and has at least three stations, a first station for receiving the sub-sample tube placed by the placement mechanism, a second station for automatically affixing labels to the sub-sample tube, and a third station for removing the sub-sample tube to which the barcode label has been affixed;

[0013] The labeling module further includes a barcode label printer, and the barcode label printer, the labeling mechanism and the barcode reader are located at the second station of the rotating disk.

[0014] In some embodiments, the labeling mechanism includes a first drive, a second drive, and two groups of rollers. The first drive is used to drive the two groups of rollers to approach each other so that the rollers contact the sub-sample tube. The second drive is used to drive the rollers to rotate. The rotation of the rollers drives the sub-sample tube to rotate, and at the same time, the barcode label is pasted along the circumference of the sub-sample tube.

[0015] In some embodiments, the sub-sample track passes through the labeling module and the dispensing module, and transfers the sub-sample tube with the barcode label to the dispensing module through the sub-sample track; the mother sample track passes through the dispensing module, and transfers the mother sample tube to the dispensing module through the mother sample track;

[0016] The mother sample track is provided with a mother sample dispensing blocker and a mother sample buffer blocker, and the sub-sample track is provided with a sub-sample dispensing blocker, a sub-sample buffer blocker and a sub-sample labeling blocker;

[0017] The sample feed rail, the mother sample buffer stopper, the sub-sample buffer stopper and the sub-sample labeling stopper are all provided with an identifier.

[0018] In some embodiments, the track module further includes a sample tube carrier track, and the sample tube carrier track is used to transfer the sample tube carrier to the sub-sample track, and the sub-sample tube is loaded through the sample tube carrier.

[0019] In some embodiments, the sample tube carrier track includes a lower track, an upper track, and a lifting mechanism, wherein the lower track is located below the sample feed track, the mother sample track, and the sub-sample track, and the upper track is located at the same level as the sample feed track, the mother sample track, and the sub-sample track, and the lifting mechanism is used to lift the sample tube carrier in the lower track to the upper track, and the upper track is connected to the sub-sample track;

[0020] The sample injection track is provided with a connected sample injection main path and a sample injection branch path. A first commutator is provided at the connection position between the sample injection main path and the sample injection branch path. The sample injection branch path is connected to the mother sample track. A second commutator is provided at the connection position between the sample injection branch path and the mother sample track. The sample injection branch path is also connected to the sub-sample track.

[0021] In some embodiments, the dispensing robot includes an X-axis robot arm, a Y-axis robot arm, a Z-axis robot arm, a pump body and an adapter. The X-axis robot arm and the Y-axis robot arm are used to move the dispensing head in the horizontal plane, the Z-axis robot arm is used to move the dispensing head in the vertical direction, the pump body is used to control the suction and dispensing of the sample, and the adapter is used to connect the dispensing head.

[0022] In some embodiments, the X-axis robot arm is provided on the Y-axis robot arm, or the Y-axis robot arm is provided on the X-axis robot arm;

[0023] The Z-direction robot arm is provided on any one of the X-direction robot arm and the Y-direction robot arm. The number of the Z-direction robot arms is one or more. The Z-direction robot arm can move independently. Each Z-direction robot arm is provided with the pump body and the adapter.

[0024] The present application also provides a sample cupping method, which is applied to the above-mentioned sample cupping device, comprising the following steps:

[0025] Using a tube supply module to supply sub-sample tubes, the tube supply module includes a tube supply mechanism and a placement mechanism, the tube supply mechanism receives and transfers the sub-sample tubes, and the placement mechanism places the sub-sample tubes at designated locations;

[0026] Automatically labeling the sub-sample tubes using a labeling module, wherein the labeling module includes a labeling mechanism and a barcode reader, wherein the labeling mechanism affixes the barcode label to the sub-sample tube, and the barcode reader verifies the barcode label information;

[0027] The mother sample tube and the daughter sample tube are transferred by a track module, the track module including an injection track, a mother sample track and a daughter sample track. The injection track receives the mother sample tube, the mother sample track transfers the mother sample tube to the dispensing module, and the daughter sample track transfers the daughter sample tube to the dispensing module.

[0028] In the dispensing module, the dispensing robot automatically picks up a dispensing tip from a dispensing tip supply device, draws the sample from the mother sample tube through the dispensing tip, and dispenses the sample into one or more sub-sample tubes.

[0029] In some embodiments, the sample cupping method further comprises the following steps:

[0030] In the tube feeding mechanism, sub-sample tubes are put into the hopper in bulk and in random order. They are lifted one by one to the discharge port by the lifting mechanism. The discharge detection component detects the orientation of the sub-sample tubes and sends an adjustment instruction to the placement mechanism, which adjusts the orientation of the sub-sample tubes to a consistent direction.

[0031] The clamping assembly and the motion assembly in the placement mechanism work together to rotate the sub-sample tube to an upright position and move it to the designated position of the labeling module;

[0032] The rotating disk of the labeling module is equipped with at least three stations, which sequentially receive, automatically label, and remove sub-sample tubes. The barcode label printer, labeling mechanism, and barcode reader are located in the second station of the rotating disk to realize automatic labeling of sub-sample tubes and label information verification.

[0033] The sub-sample track of the track module passes through the labeling module and the dispensing module, and transfers the sub-sample tubes with barcode labels to the dispensing module. The main sample track is equipped with a blocker and a buffer blocker to control the transfer and dispensing of the main sample tubes.

[0034] The dispensing robot includes an X-axis robot arm, a Y-axis robot arm, a Z-axis robot arm, a pump body and an adapter. The Z-axis robot arm can move independently. Each Z-axis robot arm is equipped with a pump body and an adapter to enable the dispensing head to automatically absorb samples and dispense them into sub-sample tubes.

[0035] Compared with the above background technology, the sample cupping device provided by the present application mainly includes a tube supply module, a labeling module, a track module and a dispensing module. The tube supply module is used to supply sub-sample tubes. The tube supply module includes a tube supply mechanism and a placement mechanism. The tube supply mechanism is used to receive and transfer sub-sample tubes. The placement mechanism is used to place the sub-sample tubes in the designated position of the labeling module. The labeling module is used to automatically label the sub-sample tubes. The labeling module includes a labeling mechanism and a barcode reader. The labeling mechanism is used to affix barcode labels to the sub-sample tubes. The barcode reader is used to verify the barcode label information. The track module is used to transport the mother sample tube and the sub-sample tube. The track module includes an injection track, a mother sample track and a sub-sample track. The injection track is used to receive the mother sample tube, the mother sample track is used to transport the mother sample tube to the dispensing module, and the sub-sample track is used to transport the sub-sample tube to the dispensing module; the dispensing module is used to dispense the sample in the mother sample tube into the sub-sample tube. The dispensing module includes a dispensing head supply device and a dispensing robot. The dispensing robot can automatically pick up the dispensing head from the dispensing head supply device, and absorb the sample from the mother sample tube through the dispensing head and dispense it into one or more sub-sample tubes.

[0036] In laboratory automation systems, traditional sample processing methods usually rely on manual or semi-automatic pipetting and packaging. This method is not only cumbersome and inefficient, but also prone to cross-contamination, affecting the accuracy of test results. In addition, when manually affixing labels to sample tubes, the label information is often difficult to identify due to irregular affixation, which brings many inconveniences to the laboratory work. In response to the defects and problems in these existing technologies, the present application provides a sample cupping device. Through its unique modular design, it realizes the automatic supply, labeling, efficient transmission and precise dispensing of sample tubes, effectively solving the above problems and significantly improving the efficiency and accuracy of sample processing.

[0037] Specifically, the sample cupping device provided in this application mainly includes a tube supply module, a labeling module, a track module and a dispensing module. The tube supply module is responsible for supplying sub-sample tubes, which includes a tube supply mechanism and a placement mechanism. The tube supply mechanism can receive and transmit sub-sample tubes to ensure that the sub-sample tubes can enter the subsequent processing flow one by one and in an orderly manner. The placement mechanism orients and accurately places the sub-sample tubes in the designated position of the labeling module, providing accurate positioning for subsequent label pasting operations, avoiding position deviations that may occur during manual placement, thereby improving the standardization and accuracy of label pasting.

[0038] The labeling module is a key component for automatically labeling sub-sample tubes. It consists of a labeling mechanism and a barcode reader. The labeling mechanism precisely applies barcode labels to sub-sample tubes, while the barcode reader verifies the accuracy of the barcode label information. This automated process not only improves labeling efficiency but also ensures accurate label information, eliminating the inconvenience caused by improper manual labeling and enhancing the standardization and traceability of sample management.

[0039] The track module plays a crucial role in transporting parent and daughter sample tubes within the sample aliquoting device. It comprises an inlet track, a parent sample track, and a daughter sample track. The inlet track receives parent sample tubes, the parent sample track transports them to the aliquoting module, and the daughter sample track transports them to the aliquoting module. This efficient transport system allows sample tubes to move quickly and accurately within the device, reducing sample dwell time during transport and improving the efficiency of the entire sample processing process.

[0040] The dispensing module is the core component for precise sample dispensing. It includes a dispensing tip supply device and a dispensing robot. The dispensing robot automatically draws a dispensing tip from the dispensing tip supply device, uses the tip to draw the sample from the mother sample tube, and accurately dispenses the sample into one or more daughter sample tubes. This automated dispensing process not only improves dispensing efficiency but also reduces the risk of cross-contamination introduced by manual operation, ensuring the accuracy and reliability of sample dispensing and thus improving the accuracy of sample test results.

[0041] Combined with the above structure and process description, it can be seen that the sample cupping device has at least the following beneficial effects: the sample cupping device realizes the automatic supply, label pasting, efficient transmission and precise injection of sample tubes, effectively solving the problems of cumbersome manual operation, low efficiency, easy cross contamination and irregular label pasting in traditional technologies, and significantly improves the sample processing efficiency and accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0042] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are merely embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without any creative work.

[0043] Figure 1 A schematic diagram of a sample cupping device provided in an embodiment of the present application;

[0044] Figure 2 A schematic diagram of a pipe supply module provided in an embodiment of the present application;

[0045] Figure 3 A schematic diagram of a labeling module provided in an embodiment of the present application;

[0046] Figure 4 A schematic diagram of a track module provided in an embodiment of the present application;

[0047] Figure 5 A schematic diagram of a dispensing module provided in an embodiment of the present application;

[0048] Figure 6 This is a flow chart of the sample cupping device provided in an embodiment of the present application.

[0049] in:

[0050] Mother sample tube 01, sub-sample tube 02, sample tube carrier 03,

[0051] Pipe supply module 100, pipe supply mechanism 110, hopper 111, lifting mechanism 112, discharge detection component 113, placement mechanism 120,

[0052] Labeling module 200, labeling mechanism 210, barcode reader 220, rotating disk 230, first station 231, second station 232, third station 233, barcode label printer 240,

[0053] Track module 300, sample injection track 310, main sample injection path 311, sample injection branch path 312, first diverter 313, second diverter 314, mother sample track 320, mother sample dispensing blocker 321, mother sample buffer blocker 322, sub-sample track 330, sub-sample dispensing blocker 331, sub-sample buffer blocker 332, sub-sample labeling blocker 333, sample tube carrier track 340, lower track 341, upper track 342, lifting mechanism 343,

[0054] Dispensing module 400 , dispensing head supply device 410 , dispensing robot 420 , X-axis robot arm 421 , Y-axis robot arm 422 , Z-axis robot arm 423 , and pump body 424 . DETAILED DESCRIPTION

[0055] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0056] In order to enable those skilled in the art to better understand the present application, the present application is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0057] Please refer to Figures 1 to 6 ,in, Figure 1 This is a schematic diagram of a sample cupping device provided in an embodiment of the present application. Figure 2 This is a schematic diagram of a pipe supply module provided in an embodiment of the present application. Figure 3 This is a schematic diagram of a labeling module provided in an embodiment of the present application. Figure 4 A schematic diagram of a track module provided in an embodiment of the present application, Figure 5 This is a schematic diagram of the injection module provided in the embodiment of the present application. Figure 6 This is a flow chart of the sample cupping device provided in an embodiment of the present application.

[0058] In a first specific embodiment, the sample cupping device provided in the embodiment of the present application mainly includes a tube supply module 100, a labeling module 200, a track module 300 and a dispensing module 400. The tube supply module 100 is used to supply sub-sample tubes 02, and the tube supply module 100 includes a tube supply mechanism 110 and a placement mechanism 120. The tube supply mechanism 110 is used to receive and transmit sub-sample tubes 02, and the placement mechanism 120 is used to place the sub-sample tubes 02 at a designated position of the labeling module 200. The labeling module 200 is used to automatically label the sub-sample tubes 02, and the labeling module 200 includes a labeling mechanism 210 and a barcode reader 220. The labeling mechanism 210 is used to attach a barcode label to the sub-sample tube 02, and the barcode reader 220 is used to verify the barcode label information. The track module 300 is used to transmit the mother sample tube 01 and the sub-sample tube 02, and the track module 300 includes an injection track 310, a mother sample track 320 and a sub-sample track 330. The sample feed track 310 is used to receive the mother sample tube 01, the mother sample track 320 is used to transport the mother sample tube 01 to the dispensing module 400, and the sub-sample track 330 is used to transport the sub-sample tube 02 to the dispensing module 400. The dispensing module 400 is used to dispense the sample from the mother sample tube 01 into the sub-sample tube 02. The dispensing module 400 includes a dispensing tip supply device 410 and a dispensing robot 420. The dispensing robot 420 can automatically extract a dispensing tip from the dispensing tip supply device 410, use the dispensing tip to draw the sample from the mother sample tube 01, and dispense it into one or more sub-sample tubes 02.

[0059] In laboratory automation systems, traditional sample processing methods usually rely on manual or semi-automatic pipetting and packaging. This method is not only cumbersome and inefficient, but also prone to cross-contamination, affecting the accuracy of test results. In addition, when manually affixing labels to sample tubes, the label information is often difficult to identify due to irregular affixation, which brings many inconveniences to the laboratory work. In response to the defects and problems in these existing technologies, the present application provides a sample cupping device. Through its unique modular design, it realizes the automatic supply, labeling, efficient transmission and precise dispensing of sample tubes, effectively solving the above problems and significantly improving the efficiency and accuracy of sample processing.

[0060] Specifically, the sample cupping device provided in the present application mainly includes a tube supply module 100, a labeling module 200, a track module 300 and a dispensing module 400. The tube supply module 100 is responsible for supplying the sub-sample tube 02, which includes a tube supply mechanism 110 and a placement mechanism 120. The tube supply mechanism 110 can receive and transmit the sub-sample tube 02, ensuring that the sub-sample tube 02 can enter the subsequent processing flow one by one and in an orderly manner. The placement mechanism 120 orients and accurately places the sub-sample tube 02 at the designated position of the labeling module 200, providing accurate positioning for subsequent label pasting operations, avoiding position deviations that may occur during manual placement, and thereby improving the standardization and accuracy of label pasting.

[0061] The labeling module 200 is the key component for automatically labeling sub-sample tubes 02. It includes a labeling mechanism 210 and a barcode reader 220. The labeling mechanism 210 accurately applies barcode labels to sub-sample tubes 02, while the barcode reader 220 verifies the accuracy of the barcode label information. This automated process not only improves labeling efficiency but also ensures accurate label information, avoiding the inconvenience of laboratory work caused by improper manual labeling and improving the standardization and traceability of sample management.

[0062] The track module 300 is responsible for transporting the parent sample tube 01 and the sub-sample tube 02 within the sample aliquoting device. It comprises a sample feed track 310, a parent sample track 320, and a sub-sample track 330. The sample feed track 310 receives the parent sample tube 01, the parent sample track 320 transports it to the dispensing module 400, and the sub-sample track 330 transports the sub-sample tube 02 to the dispensing module 400. This efficient transport system allows sample tubes to be moved quickly and accurately within the device, reducing sample dwell time during transport and improving the efficiency of the entire sample processing process.

[0063] The dispensing module 400 is the core component for achieving precise sample dispensing. It includes a dispensing tip supply device 410 and a dispensing robot 420. The dispensing robot 420 automatically extracts a dispensing tip from the dispensing tip supply device 410, uses the tip to draw sample from the mother sample tube 01, and accurately dispenses the sample into one or more daughter sample tubes 02. This automated dispensing process not only improves dispensing efficiency but also reduces the risk of cross-contamination introduced by manual operation, ensuring the accuracy and reliability of sample dispensing and thus improving the accuracy of sample testing results.

[0064] Combined with the above structure and process description, it can be seen that the sample cupping device has at least the following beneficial effects: the sample cupping device realizes the automatic supply, label pasting, efficient transmission and precise injection of sample tubes, effectively solving the problems of cumbersome manual operation, low efficiency, easy cross contamination and irregular label pasting in traditional technologies, and significantly improves the sample processing efficiency and accuracy.

[0065] Please continue to refer to Figure 1 In some embodiments, the tube feeding mechanism 110 includes a hopper 111, a discharge port, a lifting mechanism 112, and a discharge detection assembly 113. The hopper 111 is used to receive bulk sub-sample tubes 02, the discharge port is used to discharge the sub-sample tubes 02 one by one, the lifting mechanism 112 is used to lift the sub-sample tubes 02 from the hopper 111 to the discharge port, and the discharge detection assembly 113 is used to detect the orientation of the sub-sample tubes 02 and send an adjustment instruction to the placement mechanism 120, so that the placement mechanism 120 adjusts the orientation of the sub-sample tubes 02 to a consistent direction.

[0066] In this embodiment, the design of the supply mechanism 110 fully considers the automated supply requirements of sub-sample tubes 02. Through the coordinated operation of its various components, it achieves an efficient transition from bulk, disordered supply to individual, orderly supply of sub-sample tubes 02. The hopper 111, as the receiving component for sub-sample tubes 02, can accommodate bulk and potentially disordered sub-sample tubes 02, providing a foundation for subsequent operations. The discharge port is the key location for the individual discharge of sub-sample tubes 02, ensuring that the sub-sample tubes 02 can enter the subsequent process in an orderly manner.

[0067] Lifting mechanism 112 plays a crucial role within tube feeding mechanism 110, responsible for lifting the sub-sample tubes 02 within hopper 111 one by one to the discharge port. This process not only ensures smooth removal of the sub-sample tubes 02 from hopper 111 but also provides the necessary positioning for subsequent orientation adjustments. However, since the sub-sample tubes 02 may be out of order within hopper 111, their tube openings may not be uniformly oriented upon reaching the discharge port.

[0068] The discharge detection component 113 is set up to solve this problem. Through its built-in sensor, the discharge detection component 113 can accurately determine the direction of the nozzle of the sub-sample tube 02. Once the orientation information of the sub-sample tube 02 is detected, the discharge detection component 113 will pass this information to the placement mechanism 120. After receiving the adjustment instruction, the placement mechanism 120 will perform corresponding rotation operations on the sub-sample tube 02 according to the instruction. Whether it rotates clockwise or counterclockwise, its purpose is to make the nozzle direction of the sub-sample tube 02 consistent. Finally, the adjusted sub-sample tube 02 is placed in the designated position of the labeling module 200, ready for the subsequent automatic labeling operation. This series of designs and operating procedures not only improves the degree of automation of the supply of sub-sample tubes 02, but also ensures the smooth progress of subsequent operations, laying a solid foundation for the efficient operation of the entire sample cupping device.

[0069] In some embodiments, the placement mechanism 120 includes a clamping assembly and a motion assembly. The clamping assembly is used to clamp the sub-sample tube 02, and the motion assembly is used to rotate and move the sub-sample tube 02. The rotation operation includes adjusting the orientation of the sub-sample tube 02 and rotating a horizontal sub-sample tube 02 to an upright position. The movement operation is used to deliver the sub-sample tube 02 to a designated position in the labeling module 200.

[0070] In this embodiment, the placement mechanism 120 cleverly combines the functions of a clamping assembly and a motion assembly to achieve precise manipulation and positioning of the sub-sample tube 02. The clamping assembly, in the form of a jaw, securely holds the sub-sample tube 02 in a horizontal position. This design not only ensures the stability of the sub-sample tube 02 during manipulation but also provides reliable support for subsequent rotation and movement operations.

[0071] When a subsample tube 02 is clamped, its opening can be oriented in one of two ways: left or right. To ensure consistent orientation of the subsample tubes 02, the motion assembly plays a key role. Comprising a translation component and a rotation component with multiple degrees of freedom, the motion assembly enables flexible adjustment of the position and orientation of the subsample tubes 02. First, the rotation assembly adjusts the openings of the subsample tubes 02 to a consistent orientation. This adjustment ensures standardization and consistency throughout subsequent operations, avoiding operational errors caused by inconsistent orientations.

[0072] After completing the orientation adjustment, the motion assembly further rotates the horizontal sub-sample tube 02 to an upright position. This transition not only prepares the sub-sample tube 02 for entry into the labeling module 200 but also optimizes the entire operational flow of the sample dispensing device. The upright sub-sample tube 02 better adapts to the working requirements of the labeling module 200, thereby improving the accuracy and efficiency of label application.

[0073] Finally, the motion assembly precisely delivers the adjusted and upright sub-sample tube 02 to the designated position in the labeling module 200. This process not only demonstrates the high precision and flexibility of the motion assembly, but also highlights the crucial role of the placement mechanism 120 in automated sample processing. Through the coordinated operation of the clamping and motion assemblies, the placement mechanism 120 efficiently and accurately positions and transfers the sub-sample tube 02, effectively safeguarding the overall performance of the sample dispensing device.

[0074] Please continue to refer to Figure 3 In some embodiments, the labeling module 200 further includes a rotating disk 230. The rotating disk 230 is rotatable and has at least three stations. The first station 231 is used to receive the sub-sample tube 02 placed by the placement mechanism 120, the second station 232 is used to automatically label the sub-sample tube 02, and the third station 233 is used to remove the sub-sample tube 02 after the barcode label is attached. The labeling module 200 further includes a barcode label printer 240. The barcode label printer 240, the labeling mechanism 210, and the barcode reader 220 are located at the second station 232 of the rotating disk 230.

[0075] In addition to three workstations, there can also be four workstations. For example, in the illustrated structure, there is a fourth workstation between the first workstation 231 and the second workstation 232 .

[0076] In this embodiment, the labeling module 200 further optimizes the labeling process of the sub-sample tube 02 by introducing the rotating disk 230, thereby achieving efficient and automated labeling processing.

[0077] The rotating disk 230 is the core component of the labeling module 200. Its design allows for rotational operation and features at least three workstations to meet the needs of different stages of operation. The first workstation 231 receives the sub-sample tubes 02. The placement mechanism 120 places the adjusted, upright sub-sample tubes 02 here. This station ensures that the sub-sample tubes 02 are accurately positioned at the beginning of the labeling process, ready for subsequent label application.

[0078] The second station 232 is the core area of ​​the labeling process. Here, a barcode label printer 240, labeling mechanism 210, and barcode reader 220 work in tandem. The barcode label printer 240 prints barcode labels containing the necessary information, while the labeling mechanism 210 accurately affixes the printed labels to the subsample tubes 02. Simultaneously, the barcode reader 220 verifies the accuracy of the label information, ensuring that each subsample tube 02 is correctly labeled. This integrated design not only improves labeling efficiency but also enhances the accuracy of label information management, preventing subsequent inspection issues caused by labeling errors.

[0079] The third station 233 is where the barcode-labeled sub-sample tubes 02 are removed. At this station, after labeling and information verification, the sub-sample tubes 02 are removed from the rotating disk 230 and prepared for the next processing step. This station ensures the continuity of the labeling process, allowing the sub-sample tubes 02 to be smoothly removed from the labeling module 200, facilitating subsequent sample processing.

[0080] By utilizing the three-station design of the rotating disk 230, the labeling module 200 automates the entire process of receiving, labeling, and removing subsample tubes 02. This design not only improves labeling efficiency but also ensures the accuracy and consistency of label information through the integrated barcode label printer 240, labeling mechanism 210, and barcode reader 220.

[0081] In some embodiments, the labeling mechanism 210 includes a first driver, a second driver, and two sets of rollers: a driving roller and a driven roller. The first driver is used to drive the two sets of rollers toward each other, bringing them into contact with the sub-sample tube 02. The second driver is used to rotate the rollers, which in turn rotates the sub-sample tube 02, while simultaneously applying the barcode label along the circumference of the sub-sample tube 02.

[0082] In this embodiment, the design of the labeling mechanism 210 achieves efficient labeling operation on the sub-sample tube 02 by introducing a first driver, a second driver, and two sets of rollers (i.e., a driving roller and a driven roller).

[0083] The configuration of the active and passive rollers in the labeling mechanism 210 is carefully designed. In some cases, there is one active roller and two passive rollers. These three rollers are distributed around the periphery of the second station 232 in a three-point arrangement, forming a stable contact and drive system. This arrangement ensures sufficient contact between the rollers and the sub-sample tube 02, providing the necessary physical support for subsequent label application.

[0084] During the labeling process, the first actuator plays a key role. It controls the active and passive rollers to move toward the sub-sample tube 02 until they make close contact with the outer wall of the sub-sample tube 02. At this point, a portion of the adhesive backing of the barcode label printed by the barcode label printer 240 has already been attached to the sub-sample tube 02. This initial attachment state lays the foundation for the subsequent complete attachment operation.

[0085] Then, the second actuator begins to rotate, driving the active roller. Due to the friction between the active roller and the subsample tube 02, the subsample tube 02 also begins to rotate under the active roller's drive. This rotational motion allows the barcode label to be evenly applied along the circumference of the subsample tube 02. This ensures that the barcode label adheres tightly to the surface of the subsample tube 02, ensuring that the label will not fall off or shift during subsequent sample processing and testing.

[0086] The entire labeling process relies not only on precise control of the actuator, but also on good contact and appropriate friction between the roller and the sub-sample tube 02. Through the coordinated operation of the first and second actuators, and the rational configuration of the active and driven rollers, the labeling mechanism 210 can efficiently and accurately complete the labeling task.

[0087] Please continue to refer to Figure 4 In some embodiments, the sub-sample track 330 passes through the labeling module 200 and the dispensing module 400, and transfers the sub-sample tube 02 with the barcode label attached to the dispensing module 400 via the sub-sample track 330. The parent sample track 320 passes through the dispensing module 400, and transfers the parent sample tube 01 to the dispensing module 400 via the parent sample track 320. The parent sample track 320 is provided with a parent sample dispensing blocker 321 and a parent sample buffer blocker 322. The sub-sample track 330 is provided with a sub-sample dispensing blocker 331, a sub-sample buffer blocker 332, and a sub-sample labeling blocker 333. The sample feed track 310, the parent sample buffer blocker 322, the sub-sample buffer blocker 332, and the sub-sample labeling blocker 333 are all provided with identifiers.

[0088] In this embodiment, the design of the track module 300 achieves efficient transmission and precise control of sample tubes between different modules through the reasonable layout of the sub-sample track 330 and the main sample track 320.

[0089] The sub-sample track 330 passes through the labeling module 200 and the dispensing module 400, transporting the barcoded sub-sample tube 02 to the dispensing module 400. This track design ensures that the sub-sample tube 02 can smoothly enter the dispensing process after labeling, ensuring continuous sample processing. The parent sample track 320 passes through the dispensing module 400 and transports the parent sample tube 01 to the dispensing module 400, providing the necessary sample source for the dispensing operation.

[0090] The mother sample track 320 is provided with a mother sample dispensing stopper 321 and a mother sample buffer stopper 322. The mother sample buffer stopper 322 is located upstream of the mother sample dispensing stopper 321. By blocking the mother sample tube 01, it can form a buffer storage for the mother sample tube 01 upstream of the mother sample dispensing stopper 321. This design allows dispensing operations to proceed at this position while the mother sample dispensing stopper 321 is blocking the mother sample tube 01, ensuring the stability and accuracy of the dispensing process.

[0091] The subsample track 330 is equipped with a subsample dispensing blocker 331, a subsample buffer blocker 332, and a subsample labeling blocker 333. The subsample buffer blocker 332 is located upstream of the subsample dispensing blocker 331. Through its blocking action, it can form a buffer storage for the subsample tubes 02 upstream of the subsample dispensing blocker 331. This design is similar to the buffer mechanism on the main sample track 320, providing a stable sample supply for the dispensing operation of the subsample tubes 02 in the dispensing module 400.

[0092] The subsample labeling stopper 333 is located upstream of the subsample buffer stopper 332. When the subsample labeling stopper 333 blocks the sample tube carrier 03, the labeled subsample tube 02 can be loaded into the sample tube carrier 03 at this position. This layout ensures that the subsample tube 02 is labeled before entering the dispensing module 400, providing accurate identification for subsequent sample processing.

[0093] In addition, the sample feed track 310, the parent sample buffer blocker 322, the subsample buffer blocker 332, and the subsample label blocker 333 are all equipped with identifiers. These identifiers can use RFID technology to identify sample tube information. Through RFID identifiers, the system can obtain relevant information about the sample tube in real time, such as the sample number and test items, thereby achieving precise control and management of the sample processing process. This intelligent identification system not only improves the efficiency of sample processing, but also enhances the accuracy and traceability of sample management.

[0094] In some embodiments, the track module 300 further includes a sample tube carrier track 340 , which is used to transfer the sample tube carrier 03 to the sub-sample track 330 , and load the sub-sample tube 02 through the sample tube carrier 03 .

[0095] In this embodiment, the track module 300 further optimizes the sample tube transmission process. By introducing the sample tube carrier track 340, efficient transmission and precise control of the sub-sample tube 02 on the track are achieved.

[0096] The sample tube carrier track 340 is a crucial component of the track module 300, specifically used to transport the sample tube carrier 03 to the subsample track 330. Because the subsample tube 02 requires the support of the sample tube carrier 03 to move on the track, the sample tube carrier 03 has its own independent track. This design ensures a more stable and efficient transport of the subsample tube 02 within the subsample track 330. Specifically, the subsample tube 02 is first loaded onto the sample tube carrier 03, and then transported along the subsample track 330 to move the subsample tube 02.

[0097] In this design, the subsample dispensing stopper 331, subsample buffer stopper 332, and subsample labeling stopper 333 actually act on the sample tube carrier 03. When the subsample labeling stopper 333 blocks the sample tube carrier 03, the sample tube carrier 03 is unloaded. At this point, the working robot transfers the labeled subsample tube 02 from the labeling module 200 to the sample tube carrier 03. This process ensures that the subsample tube 02 is accurately loaded into the sample tube carrier 03, preparing it for subsequent transfer and dispensing operations.

[0098] When the subsample buffer blocker 332 blocks the sample tube carrier 03, it serves to buffer and store the sample tube carrier 03 containing the subsample tubes 02. This buffering mechanism provides a stable and continuous supply of subsample tubes to the dispensing module 400, ensuring smooth dispensing operations. In this way, the sample tube carriers 03 can be efficiently transported along the subsample track 330 while avoiding transport interruptions caused by accumulation of sample tube carriers 03.

[0099] When the sub-sample dispensing blocker 331 blocks the sample tube carrier 03, the dispensing module 400 performs the dispensing operation. This design ensures that the dispensing operation can be carried out accurately at the predetermined location, improving the efficiency and accuracy of dispensing. Through the use of the sample tube carrier 03, the sub-sample tube 02 is better protected and positioned during transportation, further optimizing the entire sample processing process.

[0100] In some embodiments, the sample tube carrier track 340 includes a lower track 341, an upper track 342, and a lifting mechanism 343. The lower track 341 is located below the sample feed track 310, the parent sample track 320, and the sub-sample track 330, while the upper track 342 is located on the same level as the sample feed track 310, the parent sample track 320, and the sub-sample track 330. The lifting mechanism 343 is used to lift the sample tube carrier 03 in the lower track 341 to the upper track 342, which is connected to the sub-sample track 330. The injection track 310 is provided with a connected injection main path 311 and an injection branch path 312. A first commutator 313 is provided at the connection position between the injection main path 311 and the injection branch path 312. The injection branch path 312 is connected to the parent sample track 320. A second commutator 314 is provided at the connection position between the injection branch path 312 and the parent sample track 320. The injection branch path 312 is also connected to the sub-sample track 330.

[0101] In this embodiment, the design of the sample tube carrier track 340 achieves efficient transmission and space optimization of the sample tube carrier 03 through the combination of the lower track 341, the upper track 342 and the lifting mechanism 343.

[0102] The sample tube carrier track 340 comprises a lower track 341, an upper track 342, and a lifting mechanism 343. The lower track 341 is located below the sample feed track 310, the parent sample track 320, and the sub-sample track 330. This design utilizes vertical space, saves device floor space, and optimizes the overall spatial layout. The upper track 342 is located on the same horizontal level as the sample feed track 310, the parent sample track 320, and the sub-sample track 330, ensuring that the sample tube carrier 03 is connected to the sub-sample track 330 on the same horizontal plane, achieving seamless transfer.

[0103] The lifting mechanism 343 plays a key role in the sample tube carrier track 340. It is responsible for lifting the sample tube carrier 03 located in the lower track 341 to the upper track 342. This process not only enables the sample tube carrier 03 to transfer between tracks at different heights, but also ensures that the sample tube carrier 03 can smoothly enter the sub-sample track 330, providing support for the subsequent loading and transfer of sub-sample tubes 02.

[0104] The design of the sample feed track 310 further optimizes the sample tube transport process. The sample feed track 310 comprises a connected main sample feed path 311 and a branch sample feed path 312. A first diverter 313 is located at the junction of these two paths. A second diverter 314 is located at the junction of the branch sample feed path 312 and the main sample track 320. This design allows the sample feed track 310 to flexibly direct sample tubes to different tracks, depending on the sample tube type and requirements.

[0105] In the first case, the sample injection track 310 is used to deliver the mother sample tube 01. An identifier (such as RFID) on the sample injection track 310 is used to determine whether the mother sample tube 01 needs to be dispensed. If the mother sample tube 01 does not need to be dispensed, it leaves along the main injection path 311. At this time, the first diverter 313 remains in the first state. If the mother sample tube 01 needs to be dispensed, the first diverter 313 switches to the second state, allowing the mother sample tube 01 to enter the sample injection branch 312. At the same time, the second diverter 314 switches to the second state, allowing the sample injection branch 312 to be connected only to the mother sample track 320, and the mother sample tube 01 then enters the mother sample track 320 to prepare for subsequent dispensing operations.

[0106] In the second scenario, the sample tube carrier 03 can also be introduced using the sample feed track 310. In this case, the parent sample tube 01 is typically already buffered and stored in the parent sample track 320. When the sample tube carrier 03 is introduced, the first diverter 313 switches to the second state, allowing the sample tube carrier 03 to enter the sample feed branch 312. Simultaneously, the second diverter 314 switches to the first state, connecting the sample feed branch 312 only to the sub-sample track 330, allowing the sample tube carrier 03 to enter the sub-sample track 330. This design not only improves the transfer efficiency of the sample tube carrier 03, but also ensures that the sample tube carrier 03 can be accurately and continuously fed into the sub-sample track 330, providing the necessary support for the loading of the sub-sample tube 02.

[0107] Please continue to refer to Figure 5 In some embodiments, the dispensing robot 420 includes an X-axis robot arm 421, a Y-axis robot arm 422, a Z-axis robot arm 423, a pump body 424, and an adapter. The X-axis robot arm 421 and the Y-axis robot arm 422 are used to move the dispensing head in the horizontal plane, the Z-axis robot arm 423 is used to move the dispensing head in the vertical direction, the pump body 424 is used to control the aspiration and dispensing of the sample, and the adapter is used to connect the dispensing head.

[0108] In this embodiment, the design of the dispensing robot 420 adopts an XYZ robotic arm structure, which can realize the automatic insertion and withdrawal of the dispensing head and the precise movement in three-dimensional space, thereby completing the sample suction and dispensing operations. The dispensing robot 420 includes an X-axis robotic arm 421, a Y-axis robotic arm 422, a Z-axis robotic arm 423, a pump body 424 and an adapter. Among them, the X-axis robotic arm 421 and the Y-axis robotic arm 422 are responsible for moving the dispensing head in the horizontal plane to realize the horizontal movement of the dispensing head between different positions. The Z-axis robotic arm 423 is used to move the dispensing head in the vertical direction so that the dispensing head can accurately reach the target position, whether it is to insert the dispensing head from the dispensing head supply tray, or to immerse the dispensing head in the mother sample tube 01 to absorb the sample, or to dispense the sample into the sub-sample tube 02.

[0109] Pump 424 is a key component of the dispensing robot 420, responsible for controlling sample aspiration and dispensing. Precisely controlling the operating state of pump 424 enables accurate sample aspiration and on-demand dispensing. The adapter connects the dispensing head, ensuring a stable connection between the dispensing head and the robot arm, enabling the dispensing head to accurately perform various operations driven by the robot arm.

[0110] Specifically, the X-axis robot arm 421 is arranged on the Y-axis robot arm 422, or the Y-axis robot arm 422 is arranged on the X-axis robot arm 421. This design can be flexibly adjusted according to the actual space layout and operation requirements to achieve the best operation effect.

[0111] The Z-axis robot arm 423 is provided on any one of the X-axis robot arm 421 and the Y-axis robot arm 422 . This flexibility further improves the adaptability and operating range of the dispensing robot 420 .

[0112] It's particularly noteworthy that there can be multiple Z-arms 423, each capable of independent operation. Each Z-arm 423 is equipped with a pump 424 and an adapter, allowing the dispensing robot 420 to operate multiple dispensing heads simultaneously, significantly improving dispensing efficiency. During dispensing operations, multiple independent Z-arms 423 can operate simultaneously or independently, as needed. This design not only improves efficiency but also enhances the flexibility and reliability of the entire dispensing process.

[0113] During the dispensing process, the XY mechanism (the combination of the X-axis arm 421 and the Y-axis arm 422) first moves to the top of the dispensing tip supply tray. The Z-axis mechanism (the Z-axis arm 423) lowers the adapter connected to the dispensing tip, allowing the adapter to pierce the dispensing tip and then rise. Next, the XY mechanism moves the dispensing tip to the top of the mother sample tube 01. The Z-axis mechanism descends, and the liquid level sensor detects the liquid level in the mother sample tube 01, immersing the dispensing tip into the sample in the mother sample tube 01. At this point, the pump 424 activates, drawing the sample from the mother sample tube 01 into the dispensing tip. Subsequently, the Z-axis mechanism ascends, and the XY mechanism moves the dispensing tip to the top of the daughter sample tube 02. The Z-axis mechanism descends again, and the pump 424 activates, dispensing the sample in the dispensing tip into the daughter sample tube 02 as needed. If dispensing into multiple daughter sample tubes 02 is required, the above dispensing process is repeated. When all sub-sample tubes 02 are dispensed, the Z-direction mechanism rises, and the XY-direction mechanism drives the dispensing head to move to the dispensing head discard position, and the used dispensing head is discarded into the discard bucket.

[0114] This design not only increases the automation level of the dispensing operation but also enables efficient sample dispensing through the use of multiple independently operating Z-axis robotic arms 423. In particular, the independent Z-axis robotic arms 423 enable the dispensing robot 420 to more flexibly respond to varying dispensing requirements, further enhancing the performance and efficiency of the entire sample dispensing device.

[0115] In a specific embodiment, the present application provides an efficient and automated sample cupping device, the core components of which include sub-tube supply, automatic labeling, track transmission, dispensing head supply and dispensing robot arm. The sub-tube supply module receives bulk sub-sample tubes 02 through a hopper, and uses the lifting mechanism 112 and the discharge detection component 113 to sort and orient them, ensuring that the sub-sample tubes 02 are transported one by one to the labeling position in a uniform direction. The automatic labeling module 200 affixes barcode labels to the sub-sample tubes 02 through the labeling mechanism 210, and uses the barcode reader 220 to scan and verify the barcode, and then transports the labeled sub-sample tubes 02 to the track module 300. The track module 300 is responsible for accurately transporting the mother sample tube 01 and the sub-sample tube 02 to the dispensing position. The dispensing robot arm 420 obtains the dispensing head at the dispensing head supply device 410, extracts the sample from the mother sample tube 01, and accurately dispenses the sample into one or more sub-sample tubes 02, achieving efficient and accurate sample dispensing.

[0116] In a specific embodiment, the sample cupping method provided in the embodiment of the present application is applied to the above-mentioned sample cupping device, comprising the following steps:

[0117] The sub-sample tubes 02 are supplied by a tube supply module 100 , which includes a tube supply mechanism 110 and a placement mechanism 120 . The tube supply mechanism 110 receives and transfers the sub-sample tubes 02 , and the placement mechanism 120 places the sub-sample tubes 02 at designated locations.

[0118] The sub-sample tube 02 is automatically labeled by the labeling module 200. The labeling module 200 includes a labeling mechanism 210 and a barcode reader 220. The labeling mechanism 210 affixes the barcode label to the sub-sample tube 02, and the barcode reader 220 verifies the barcode label information.

[0119] The track module 300 is used to transport the mother sample tube 01 and the sub-sample tube 02. The track module 300 includes an injection track 310, a mother sample track 320, and a sub-sample track 330. The injection track 310 receives the mother sample tube 01, the mother sample track 320 transports the mother sample tube 01 to the dispensing module 400, and the sub-sample track 330 transports the sub-sample tube 02 to the dispensing module 400.

[0120] In the dispensing module 400 , the dispensing robot 420 automatically picks up a dispensing tip from the dispensing tip supply device 410 , draws a sample from the mother sample tube 01 through the dispensing tip, and dispenses the sample into one or more sub-sample tubes 02 .

[0121] The sample splitting method provided herein significantly improves the efficiency and accuracy of sample processing through automated processes. Specifically, this method utilizes the tube supply module 100 to automatically supply subsample tubes 02, reducing the need for manual operation and the likelihood of operational errors. The automatic labeling function of the labeling module 200 ensures accurate sample tracking and management while avoiding the inconsistencies and recognition errors that can arise from manual labeling.

[0122] Furthermore, the integrated design of the track module 300 allows for smoother and more controlled transfer of the parent sample tube 01 and the daughter sample tube 02, reducing sample waiting time during processing and optimizing the entire sample dispensing process. The automated dispensing process of the dispensing module 400 not only improves sample dispensing accuracy but also reduces the risk of sample contamination, thereby enhancing the reliability of sample testing.

[0123] In summary, this method achieves high-throughput and high-efficiency sample aliquoting through automated and precisely controlled steps, significantly improving the performance of laboratory automation systems while ensuring accurate tracking and management of sample information.

[0124] In some embodiments, the sample cupping method further comprises the following steps:

[0125] In the tube feeding mechanism 110, the sub-sample tubes 02 are randomly placed in bulk into the hopper 111 and lifted one by one to the discharge port by the lifting mechanism 112. The discharge detection component 113 detects the orientation of the sub-sample tubes 02 and sends an adjustment instruction to the placement mechanism 120. The placement mechanism 120 adjusts the orientation of the sub-sample tubes 02 to a consistent direction.

[0126] The clamping assembly 121 and the moving assembly 122 in the placement mechanism 120 work together to rotate the sub-sample tube 02 to an upright position and move it to a designated position of the labeling module 200;

[0127] The rotating disk 230 of the labeling module 200 is provided with at least three stations, which sequentially receive, automatically label, and remove the sub-sample tubes 02. The barcode label printer 240, the labeling mechanism 210, and the barcode reader 220 are located at the second station of the rotating disk 230 to automatically label the sub-sample tubes 02 and verify the label information.

[0128] The sub-sample track 330 of the track module 300 passes through the labeling module 200 and the dispensing module 400, and transfers the sub-sample tube 02 with the barcode label attached to the dispensing module 400. The mother sample track 320 is equipped with a mother sample dispensing blocker 321 and a mother sample buffer blocker 322, which are used to control the transfer and dispensing of the mother sample tube 01.

[0129] The dispensing robot 420 includes an X-axis robot arm 421, a Y-axis robot arm 422, a Z-axis robot arm 423, a pump body 424 and an adapter 425. The Z-axis robot arm 423 can move independently. Each Z-axis robot arm 423 is equipped with a pump body 424 and an adapter 425 to enable the dispensing head to automatically absorb samples and dispense them into the sub-sample tube 02.

[0130] like Figure 6 As shown, the workflow of the sample splitting device provided herein begins when a mother sample tube 01 enters the splitting track. First, an RFID reader identifies the mother sample tube 01 to determine whether it requires splitting. If not, the mother sample tube 01 flows directly through the sample track and out of the module. If splitting is required, the process continues.

[0131] For mother sample tubes 01 that require cupping, they enter the mother sample track 320 and wait for dispensing at the mother sample dispensing position. At this point, the dispensing robot 420 detects the liquid level in the mother tube to ensure the accuracy of the dispensing operation. Next, the sample tube carriers 03 are randomly placed in bulk into the hopper 111 and lifted one by one to the discharge port by the lifting mechanism 112. The discharge detection assembly 113 detects the orientation of the sub-sample tubes 02 and sends adjustment instructions to the placement mechanism 120 to ensure consistent orientation of the sub-sample tubes 02.

[0132] The placement mechanism 120 includes a clamping assembly 121 and a motion assembly 122, which rotate the sub-sample tube 02 to a vertical position and move it to a designated position in the labeling module 200. In the labeling module 200, the rotating disk 230 has at least three stations: the first station 231 is used to receive the sub-sample tube 02 placed by the placement mechanism 120, the second station 232 is used to automatically apply the label, and the third station 233 is used to remove the sub-sample tube 02 after the label is applied.

[0133] The barcode label printer 240 is located at the second station 232 of the rotating disk 230 and prints barcode labels. The labeling mechanism 210 includes a first driver 211, a second driver 212, and two sets of rollers (a driving roller 213 and a driven roller 214). The first driver 211 drives the rollers toward the subsample tube 02, while the second driver 212 rotates the rollers, driving the subsample tube 02 to rotate and simultaneously applying the barcode label along the circumference of the subsample tube 02.

[0134] The labeled sub-sample tubes 02 are then placed on the sample tube carrier 03 and transported to the dispensing module 400 via the sub-sample track 330. In the dispensing module 400, the dispensing robot 420 automatically retrieves a dispensing tip from the tip supply device 410 and uses it to draw sample from the mother sample tube 01 and dispense it into one or more sub-sample tubes 02. After dispensing is complete, the tip is discarded, and the mother sample tube 01 and sub-sample tubes 02 exit the cupping module.

[0135] The above process covers the entire process from receiving the mother sample tube 01, supplying and labeling the sub-sample tube 02, to sample dispensing and output, realizing the automation and efficient operation of the sample cupping device.

[0136] It should be noted that many of the components mentioned in this application are universal standard parts or components known to those skilled in the art, and their structures and principles can be learned by those skilled in the art through technical manuals or conventional experimental methods.

[0137] It should be noted that, in this specification, relational terms such as first and second are merely used to distinguish one entity from other entities, but do not necessarily require or imply any actual relationship or order between these entities.

[0138] The above is a detailed introduction to the sample cupping device and method provided by the present application. Specific examples are used herein to illustrate the principles and implementation methods of the present application. The description of the above embodiments is only intended to help understand the method and core ideas of the present application. It should be pointed out that, for those skilled in the art, without departing from the principles of the present application, several improvements and modifications can be made to the present application, and these improvements and modifications also fall within the scope of protection of the claims of the present application.

Claims

1. A sample cupping device, characterized in that: include: a tube supply module, configured to supply sub-sample tubes, the tube supply module comprising a tube supply mechanism and a placement mechanism, the tube supply mechanism being configured to receive and transfer the sub-sample tubes, and the placement mechanism being configured to place the sub-sample tubes at designated locations; a labeling module for automatically attaching labels to the sub-sample tubes, the labeling module comprising a labeling mechanism and a barcode reader, the labeling mechanism for attaching barcode labels to the sub-sample tubes, and the barcode reader for verifying the barcode label information; A track module is used to transport the mother sample tube and the daughter sample tube. The track module includes an injection track, a mother sample track, and a daughter sample track. The injection track is used to receive the mother sample tube, the mother sample track is used to transport the mother sample tube to the dispensing module, and the daughter sample track is used to transport the daughter sample tube to the dispensing module. The dispensing module is used to dispense the sample in the mother sample tube into the sub-sample tube. The dispensing module includes a dispensing head supply device and a dispensing robot. The dispensing robot can automatically pick up the dispensing head from the dispensing head supply device, and use the dispensing head to absorb the sample from the mother sample tube and dispense it into one or more sub-sample tubes.

2. The sample cupping device according to claim 1, characterized in that: The tube feeding mechanism includes a hopper, a discharge port, a lifting mechanism, and a discharge detection assembly. The hopper is used to receive bulk sub-sample tubes. The discharge port is used to output the sub-sample tubes one by one. The lifting mechanism is used to lift the sub-sample tubes from the hopper to the discharge port. The discharge detection assembly is used to detect the orientation of the sub-sample tubes and send an adjustment instruction to the placement mechanism, so that the placement mechanism adjusts the orientation of the sub-sample tubes to a consistent direction. And / or, The placement mechanism includes a clamping assembly and a motion assembly, wherein the clamping assembly is used to clamp the sub-sample tube, and the motion assembly is used to rotate and move the sub-sample tube; the rotation operation includes adjusting the orientation of the sub-sample tube and rotating the horizontal sub-sample tube to an upright state, and the movement operation is used to send the sub-sample tube to a designated position of the labeling module.

3. The sample cupping device according to claim 1, characterized in that: The labeling module further includes a rotating disk, which is rotatable and has at least three stations, wherein the first station is used to receive the sub-sample tube placed by the placement mechanism, the second station is used to automatically label the sub-sample tube, and the third station is used to remove the sub-sample tube to which the barcode label has been affixed; the labeling module further includes a barcode label printer, wherein the barcode label printer, the labeling mechanism, and the barcode reader are located at the second station of the rotating disk; and / or, The labeling mechanism includes a first driver, a second driver, and two groups of rollers. The first driver is used to drive the two groups of rollers to approach each other so that the rollers contact the sub-sample tube. The second driver is used to drive the rollers to rotate. The rotation of the rollers drives the sub-sample tube to rotate, and at the same time, the barcode label is pasted along the circumference of the sub-sample tube.

4. The sample cupping device according to claim 1, characterized in that: The sub-sample track passes through the labeling module and the dispensing module, and transfers the sub-sample tube with the barcode label to the dispensing module through the sub-sample track; the mother sample track passes through the dispensing module, and transfers the mother sample tube to the dispensing module through the mother sample track; The mother sample track is provided with a mother sample dispensing blocker and a mother sample buffer blocker, and the sub-sample track is provided with a sub-sample dispensing blocker, a sub-sample buffer blocker and a sub-sample labeling blocker; The sample feed rail, the mother sample buffer stopper, the sub-sample buffer stopper and the sub-sample labeling stopper are all provided with an identifier.

5. The sample cupping device according to claim 1, characterized in that: The track module further includes a sample tube carrier track, which is used to transfer a sample tube carrier to the sub-sample track, and to load a sub-sample tube through the sample tube carrier.

6. The sample cupping device according to claim 5, characterized in that: The sample tube carrier track includes a lower track, an upper track, and a lifting mechanism. The lower track is located below the sample feed track, the mother sample track, and the sub-sample track. The upper track is located at the same level as the sample feed track, the mother sample track, and the sub-sample track. The lifting mechanism is used to lift the sample tube carrier in the lower track to the upper track. The upper track is connected to the sub-sample track. The sample injection track is provided with a connected sample injection main path and a sample injection branch path. A first commutator is provided at the connection position between the sample injection main path and the sample injection branch path. The sample injection branch path is connected to the mother sample track. A second commutator is provided at the connection position between the sample injection branch path and the mother sample track. The sample injection branch path is also connected to the sub-sample track.

7. The sample cupping device according to claim 1, characterized in that: The dispensing robot includes an X-axis robot arm, a Y-axis robot arm, a Z-axis robot arm, a pump body and an adapter. The X-axis robot arm and the Y-axis robot arm are used to move the dispensing head in the horizontal plane, the Z-axis robot arm is used to move the dispensing head in the vertical direction, the pump body is used to control the suction and dispensing of the sample, and the adapter is used to connect the dispensing head.

8. The sample cupping device according to claim 7, characterized in that: The X-axis robot arm is arranged on the Y-axis robot arm, or the Y-axis robot arm is arranged on the X-axis robot arm; The Z-direction robot arm is provided on any one of the X-direction robot arm and the Y-direction robot arm. The number of the Z-direction robot arms is one or more. The Z-direction robot arm can move independently. Each Z-direction robot arm is provided with the pump body and the adapter.

9. A sample cupping method, applied to the sample cupping device according to any one of claims 1 to 8, characterized in that: The following steps are involved: Using a tube supply module to supply sub-sample tubes, the tube supply module includes a tube supply mechanism and a placement mechanism, the tube supply mechanism receives and transfers the sub-sample tubes, and the placement mechanism places the sub-sample tubes at designated locations; Automatically labeling the sub-sample tubes using a labeling module, wherein the labeling module includes a labeling mechanism and a barcode reader, wherein the labeling mechanism affixes the barcode label to the sub-sample tube, and the barcode reader verifies the barcode label information; The mother sample tube and the daughter sample tube are transferred by a track module, the track module including an injection track, a mother sample track and a daughter sample track. The injection track receives the mother sample tube, the mother sample track transfers the mother sample tube to the dispensing module, and the daughter sample track transfers the daughter sample tube to the dispensing module. In the dispensing module, the dispensing robot automatically picks up a dispensing tip from a dispensing tip supply device, draws the sample from the mother sample tube through the dispensing tip, and dispenses the sample into one or more sub-sample tubes.

10. The sample cupping method according to claim 9, characterized in that: The following steps are also included: In the tube feeding mechanism, sub-sample tubes are put into the hopper in bulk and in random order. They are lifted one by one to the discharge port by the lifting mechanism. The discharge detection component detects the orientation of the sub-sample tubes and sends an adjustment instruction to the placement mechanism, which adjusts the orientation of the sub-sample tubes to a consistent direction. The clamping assembly and the motion assembly in the placement mechanism work together to rotate the sub-sample tube to an upright position and move it to the designated position of the labeling module; The rotating disk of the labeling module is equipped with at least three stations, which sequentially receive, automatically label, and remove sub-sample tubes. The barcode label printer, labeling mechanism, and barcode reader are located in the second station of the rotating disk to realize automatic labeling of sub-sample tubes and label information verification. The sub-sample track of the track module passes through the labeling module and the dispensing module, and transfers the sub-sample tubes with barcode labels to the dispensing module. The main sample track is equipped with a blocker and a buffer blocker to control the transfer and dispensing of the main sample tubes. The dispensing robot includes an X-axis robot arm, a Y-axis robot arm, a Z-axis robot arm, a pump body and an adapter. The Z-axis robot arm can move independently. Each Z-axis robot arm is equipped with a pump body and an adapter to enable the dispensing head to automatically absorb samples and dispense them into sub-sample tubes.

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