Intervertebral fusion cage and method for manufacturing an intervertebral fusion cage

Abstract

The present application provides an intervertebral fusion cage and a manufacturing method thereof, wherein the intervertebral fusion cage comprises a first end plate assembly, a second end plate assembly and an elastic support assembly; the two ends of the elastic support assembly are connected with the first end plate assembly and the second end plate assembly respectively; the first end plate assembly comprises an end plate body, a back-off prevention tooth structure and a porous structure; one end of the end plate body is connected with the elastic support assembly, and the other end is provided with a bearing contact surface; the back-off prevention tooth structure and the porous structure are arranged on the bearing contact surface respectively; the back-off prevention tooth structure protrudes from the bearing contact surface and is used for fixed connection with the vertebral tissue; the porous structure has hollow holes inside and is used for allowing a part of the growing vertebral tissue to extend into the porous structure. The present application solves the problem of low contact area between the intervertebral fusion cage and the vertebral bone in the prior art, and further solves the problems of postoperative prosthesis dislocation or loosening, end plate bone destruction and poor fusion efficiency.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to an intervertebral fusion cage and a manufacturing method thereof. BACKGROUND

[0002] Intervertebral fusion is one of the common surgical methods for treating lumbar intervertebral disc and cervical degeneration, lumbar and cervical instability, spinal stenosis and other diseases. It promotes the bone fusion between adjacent upper and lower vertebral bodies by implanting an intervertebral fusion cage and often accompanied by bone graft material to achieve the purpose of stabilizing the vertebrae, relieving nerve compression and restoring the height of the intervertebral space. This surgical technique is widely welcomed because it can effectively improve the patient's symptoms and reduce surgical trauma.

[0003] The existing intervertebral fusion cage usually has poor self-stability. Some fusion cages cannot well adapt to or maintain the anatomical morphology of the intervertebral space after implantation, and often appear the phenomenon of postoperative prosthesis dislocation or loosening, which leads to pain in patients or a series of complications, and in severe cases, further secondary surgery is required. Especially in the early healing stage, the intervertebral fusion cage may shift because it is not firmly fixed to the vertebrae, thereby reducing the fusion effect. Therefore, in order to improve the stability of the intervertebral fusion cage connected to the vertebrae, a fusion cage with anti-backout function is usually designed.

[0004] At present, the intervertebral fusion cage with anti-backout function in the prior art mainly includes an intervertebral fusion cage with anti-backout teeth and an intervertebral fusion cage with a screw. Among them, the existing intervertebral fusion cage with anti-backout teeth usually has a low contact area with the vertebrae, which leads to endplate bone destruction or poor fusion efficiency of the prosthesis (intervertebral fusion cage structure), thereby limiting the long-term stability of the prosthesis. The existing intervertebral fusion cage with a screw usually relies on the reliable connection of the screw with the vertebrae, which can maintain the long-term stability of the prosthesis, but the placement of the screw will cause a large amount of destruction of the bone of the vertebrae, and the matching degree of the intervertebral fusion cage with a screw to the endplate (for example, the contact surface of the vertebrae) is relatively high. The mismatched endplate will worsen the stress condition of the screw and the vertebrae, thereby causing abnormal fracture of the screw or damage to the vertebrae.

[0005] In summary, the existing intervertebral fusion cage has a low contact area with the vertebrae, which is prone to postoperative prosthesis dislocation or loosening, endplate bone destruction, and poor fusion efficiency. SUMMARY

[0006] The present application provides an intervertebral fusion cage and a manufacturing method thereof to solve the problem of low contact area between the intervertebral fusion cage and the vertebrae in the prior art, which is prone to postoperative prosthesis dislocation or loosening, endplate bone destruction, and poor fusion efficiency.

[0007] In order to solve the above problems, according to one aspect of the present application, an intervertebral fusion cage is provided, comprising: a first endplate assembly, a second endplate assembly and an elastic support assembly; the first endplate assembly and the second endplate assembly are identical in structure; the two ends of the elastic support assembly are connected with the first endplate assembly and the second endplate assembly respectively, the elastic support assembly is made of elastic material, and the elastic force generated by the elastic support assembly is used to support the first endplate assembly and the second endplate assembly to abut against the vertebral tissue respectively; wherein the first endplate assembly comprises an endplate body, an anti-back tooth structure and a porous structure, one end of the endplate body is connected with the elastic support assembly, and the other end is provided with a bearing contact surface for abutting against the vertebral tissue; the anti-back tooth structure and the porous structure are arranged on the bearing contact surface respectively; the anti-back tooth structure protrudes from the bearing contact surface and is used to be fixedly connected with the vertebral tissue; the porous structure has hollow holes inside and is used for the growing vertebral tissue to extend into the porous structure to be fixedly connected with the porous structure.

[0008] Further, the anti-back tooth structure comprises a plurality of protruding teeth, and the plurality of protruding teeth are arranged on the bearing contact surface at intervals; the porous structure comprises a plurality of porous bodies, and the porous bodies have hollow holes inside; at least one porous body is arranged between two adjacent protruding teeth.

[0009] Further, the first endplate assembly has three mutually perpendicular first, second and third directions; the end surface of the endplate body in the first direction is the bearing contact surface, the plurality of protruding teeth are arranged in a row along the second direction and in a column along the third direction on the bearing contact surface; wherein in one column of protruding teeth, one porous body is arranged between two adjacent protruding teeth and connected with the two adjacent protruding teeth respectively; and / or in one row of protruding teeth, the plurality of protruding teeth are arranged at equal intervals.

[0010] Further, in one column of protruding teeth, the porous body between two adjacent protruding teeth protrudes towards the vertebral tissue, and the distance of the protruding end from the bearing contact surface along the first direction is a first distance; the protruding tooth protrudes towards the vertebral tissue, and the distance of the protruding end from the bearing contact surface along the first direction is a second distance; wherein the first distance is the same as the second distance; and / or the second distance is greater than or equal to 0.5 mm and less than or equal to 1.5 mm.

[0011] Further, in one column of protruding teeth, the distance between two adjacent protruding teeth is greater than or equal to 0.8 mm and less than or equal to 3 mm; and / or in one row of protruding teeth, the distance between two adjacent protruding teeth is greater than or equal to 0.8 mm and less than or equal to 3 mm.

[0012] Further, the protruding teeth have the same shape as the outer shape of the porous body; and / or, the protruding teeth are one of a trapezoidal shape, a pyramid shape, and a prism shape; and / or, the protruding teeth protrude towards the vertebral tissue, and the distance between the protruding end of the protruding teeth and the bearing contact surface in the first direction is a second distance, the second distance being greater than or equal to 0.5 mm and less than or equal to 1.5 mm; and / or, the distance between the two ends of the protruding teeth in the second direction is greater than or equal to 0.2 mm and less than or equal to 1 mm; and / or, the distance between the two ends of the protruding teeth in the third direction is greater than or equal to 0.2 mm and less than or equal to 1 mm; and / or, the porous body comprises a plurality of connection columns arranged in a cross-shaped mesh, one end of each connection column is connected to another connection column or protruding tooth, and the other end of each connection column is connected to another connection column or protruding tooth, so that any end of the connection column is not suspended.

[0013] Further, the protruding teeth are cut by a plane parallel to the first direction to obtain a cross section of the protruding teeth, and the shape of the cross section is a triangle or a trapezoid; and / or, when the protruding teeth are a prism shape, the protruding teeth are cut by a plane parallel to the first direction to obtain a cross section of the protruding teeth, and the shape of the cross section is a triangle or a trapezoid, one side of the triangle or one leg of the trapezoid has an included angle with the first direction, and the included angle is a first included angle, the first included angle being greater than or equal to 0° and less than or equal to 60°.

[0014] Further, the porosity of the porous structure is greater than or equal to 20% and less than or equal to 80%; and / or, the diameter of the hollow hole is greater than or equal to 0.2 mm and less than or equal to 1.5 mm; and / or, the porous structure and the anti-backout tooth structure are regarded as a whole, and the volume ratio of the porous structure in the whole is greater than or equal to 20% and less than or equal to 80%.

[0015] Further, the bearing contact surface has a hollow groove, and a part of the porous structure is arranged in the hollow groove, and the part is a first part, and the first part is limited by the inner wall of the hollow groove.

[0016] Further, the end of the first part towards the vertebral tissue is flush with the bearing contact surface, so that the first part and the bearing contact surface jointly abut against the vertebral tissue.

[0017] Further, a shape of at least a part of the bearing contact surface is matched with a shape of an end of the vertebral tissue towards the bearing contact surface, so that the at least a part of the bearing contact surface is fitted with the vertebral tissue; and / or, the first endplate assembly has three mutually perpendicular first, second and third directions; the elastic support assembly includes a plurality of elastic bodies, the plurality of elastic bodies are arranged at intervals along the second and third directions; the elastic bodies extend in a wave shape along the first direction to form a wave plate structure, the wave plate structure generates elastic force through deformation; and / or, the first endplate assembly has three mutually perpendicular first, second and third directions; a middle part of the intervertebral fusion cage has a through space, the through space penetrates the endplate body of the first endplate assembly and the endplate body of the second endplate assembly; wherein, along the first direction, projections of the through space in the same plane perpendicular to the first direction are arranged at intervals with projections of the elastic support assembly, projections of the anti-back tooth structure and projections of the porous structure respectively; the through space is used for accommodating the vertebral tissue.

[0018] According to another aspect of the present application, an intervertebral fusion cage manufacturing method is provided for manufacturing the above intervertebral fusion cage, the intervertebral fusion cage manufacturing method includes the following steps: obtaining the intervertebral fusion cage by 3D printing and / or cutting processing; processing a shape of at least a part of the bearing contact surface to match a shape of an end of the vertebral tissue towards the bearing contact surface, so that the at least a part of the bearing contact surface is fitted with the vertebral tissue; processing a plurality of protruding teeth arranged at intervals on the bearing contact surface, processing a plurality of porous bodies, and connecting two ends of the porous body between two adjacent protruding teeth with the two adjacent protruding teeth respectively.

[0019] According to the technical scheme of the present application, the present application provides an intervertebral fusion cage, which includes: a first endplate assembly, a second endplate assembly and an elastic support assembly; the first endplate assembly and the second endplate assembly have the same structure; the two ends of the elastic support assembly are connected with the first endplate assembly and the second endplate assembly respectively, the elastic support assembly is made of elastic material, and the elastic force generated thereby is used to support the first endplate assembly and the second endplate assembly to abut against the vertebral tissue respectively; wherein, the first endplate assembly includes an endplate body, an anti-back tooth structure and a porous structure, an end face of one end of the endplate body is connected with the elastic support assembly, an end face of the other end is a bearing contact surface, the bearing contact surface is used to abut against the vertebral tissue; the anti-back tooth structure and the porous structure are arranged on the bearing contact surface respectively; the anti-back tooth structure protrudes from the bearing contact surface and is used to be fixedly connected with the vertebral tissue; the porous structure has hollow holes inside, and a part of the growing vertebral tissue is inserted into the porous structure to be fixedly connected with the porous structure.

[0020] The application sets the anti-retreating tooth structure, so that the anti-retreating tooth structure can be inserted into the vertebral tissue, ensures the connection strength with the vertebral tissue, and further prevents the intervertebral fusion cage from loosening or falling out due to stress damage; the porous structure is set, so that the bone tissue grown by the vertebral tissue can extend into the porous structure, the contact area with the vertebral tissue is improved, the connection strength and long-term stability of the intervertebral fusion cage and the vertebral tissue are further improved, with the growth of the bone tissue, the mechanical strength of the vertebral tissue and the porous structure is gradually improved, and then the stress borne by the anti-retreating tooth structure can be reduced, and the service life of the intervertebral fusion cage is further improved; the elastic support assembly is set by using elastic material, so that the elastic force generated by the elastic support assembly can support the first end plate assembly and the second end plate assembly to abut against the vertebral tissue respectively, and the rigidity of the intervertebral fusion cage as a whole is reduced, so that the first end plate assembly and the second end plate assembly can be self-adaptively adjusted to a certain extent; compared with the structure of the existing high-rigidity fusion cage which cannot be self-adaptively adjusted, the intervertebral fusion cage can be adjusted according to different bone conditions of patients by setting the elastic support assembly, so that the rigidity of the intervertebral fusion cage can match various patients, and the abnormal conditions such as collapse of the vertebral end plate of the vertebral tissue of the osteoporosis patient can be effectively prevented; the application solves the problems of low contact area between the intervertebral fusion cage and the vertebra in the prior art, and further postoperative prosthesis falling out or loosening, end plate bone destruction and poor fusion efficiency; the application has simple structure and low cost, is convenient for processing, production and installation, and is suitable for large-scale popularization and use. BRIEF DESCRIPTION OF DRAWINGS

[0021] The drawings accompanying the specification of this application form a part thereof, serve to provide further understanding of the application, and together with the description of the application provided below, explain the application, and do not constitute an improper limitation of the application. In the drawings:

[0022] Figure 1 A specific structure schematic diagram of the intervertebral fusion cage provided by the embodiment of the application is shown;

[0023] Figure 2 A cross-sectional schematic diagram of the protruding tooth obtained by taking a plane parallel to the first direction is shown;

[0024] Figure 3 An enlarged view of part of the structure at the positions of the protruding tooth and the porous body provided by the embodiment of the application is shown;

[0025] Figure 4 An enlarged view of part of the structure at the positions of the protruding tooth and the porous body provided by another embodiment of the application is shown;

[0026] Figure 5 A local enlarged view of the connecting column position provided by the first embodiment of the application is shown;

[0027] Figure 6 A partial enlarged view of the connecting post position provided by the second embodiment of the present application is shown;

[0028] Figure 7 A partial enlarged view of the connecting post position provided by the third embodiment of the present application is shown;

[0029] Figure 8 A partial enlarged view of the connecting post position provided by the fourth embodiment of the present application is shown;

[0030] Figure 9 A partial enlarged view of the connecting post position provided by the fifth embodiment of the present application is shown;

[0031] Figure 10 A partial enlarged view of the connecting post position provided by the sixth embodiment of the present application is shown.

[0032] Among the above-mentioned drawings, the following reference signs are included:

[0033] 10, first end plate assembly; 11, end plate body; 111, bearing contact surface; 12, anti-back tooth structure; 121, protruding tooth; 13, porous structure; 131, hollow hole; 132, porous body; 133, connecting post; 134, first part;

[0034] 20, second end plate assembly;

[0035] 30, elastic support assembly; 31, elastic body;

[0036] 40, through space. DETAILED DESCRIPTION

[0037] The technical solutions in the embodiments of the present application will be described clearly and completely below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. The description of the at least one exemplary embodiment is actually only illustrative, but not as any limitation on the present application and its application or use. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without any creative work, are within the scope of protection of the present application.

[0038] As Figures 1 to 10As shown, the embodiment of the present application provides an intervertebral fusion cage, comprising: a first end plate assembly 10, a second end plate assembly 20 and an elastic support assembly 30; the first end plate assembly 10 and the second end plate assembly 20 are the same structure; the two ends of the elastic support assembly 30 are connected with the first end plate assembly 10 and the second end plate assembly 20 respectively, the elastic support assembly 30 is made of elastic material, and the elastic force generated by the elastic support assembly 30 is used to support the first end plate assembly 10 and the second end plate assembly 20 to abut with the vertebral tissue respectively; wherein the first end plate assembly 10 comprises an end plate body 11, a tooth structure 12 and a porous structure 13, one end of the end plate body 11 is connected with the elastic support assembly 30, and the other end is a bearing contact surface 111, the bearing contact surface 111 is used to abut with the vertebral tissue; the tooth structure 12 and the porous structure 13 are arranged on the bearing contact surface 111 respectively; the tooth structure 12 protrudes from the bearing contact surface 111 and is used to be fixedly connected with the vertebral tissue; the porous structure 13 has a hollow hole 131 inside, and a part of the growing vertebral tissue is inserted into the porous structure 13 to be fixedly connected with the porous structure 13.

[0039] The tooth structure 12 can be inserted into the vertebral tissue, the connection strength with the vertebral tissue is ensured, and the intervertebral fusion cage can be prevented from loosening or falling out due to stress damage; the bone tissue of the growing vertebral tissue can be inserted into the porous structure 13, the contact area with the vertebral tissue is increased, the connection strength and long-term stability of the intervertebral fusion cage and the vertebral tissue are further improved, the mechanical strength of the vertebral tissue and the porous structure 13 is gradually improved with the growth of the bone tissue, the stress borne by the tooth structure 12 can be further reduced, and the service life of the intervertebral fusion cage is further improved; the elastic support assembly 30 is made of elastic material, the elastic force generated by the elastic support assembly 30 can support the first end plate assembly 10 and the second end plate assembly 20 to abut with the vertebral tissue respectively, and the rigidity of the intervertebral fusion cage as a whole is reduced, so that the first end plate assembly 10 and the second end plate assembly 20 can be self-adaptively adjusted to a certain extent; compared with the structure design of the existing high-rigidity fusion cage which cannot be self-adaptively adjusted, the intervertebral fusion cage can be adjusted according to different bone conditions of patients through the elastic support assembly 30, so that the rigidity of the intervertebral fusion cage can match various patients, and the abnormal conditions such as vertebral end plate collapse of the vertebral tissue of the osteoporosis patient can be effectively prevented; the present application solves the problems of low contact area between the intervertebral fusion cage and the vertebral bone in the prior art, and the problems of postoperative prosthesis falling out or loosening, end plate bone destruction and poor fusion efficiency are easily caused; the present application has simple structure and low cost, is convenient for processing, production and installation, and is suitable for large-scale popularization and use.

[0040] It should be noted that: the intervertebral fusion cage can be designed and adjusted according to different bone conditions (for example: normal bone, osteoporosis, etc.) of patients through the design of the elastic support assembly 30, so that the stiffness of the fusion cage can be matched with various patients, preventing the collapse of the vertebral endplate in patients with poor bone quality, avoiding a series of complications and secondary surgery, and having beneficial effects in terms of economy, surgical quality, recovery speed and the like.

[0041] As Figure 1 shown, the anti-back tooth structure 12 includes a plurality of protruding teeth 121, and the plurality of protruding teeth 121 are arranged at intervals on the bearing contact surface 111; the porous structure 13 includes a plurality of porous bodies 132, and the porous body 132 has a hollow hole 131 inside, and at least one porous body 132 is arranged between two adjacent protruding teeth 121.

[0042] By arranging the protruding teeth 121 at intervals on the bearing contact surface 111, the contact points with the vertebral tissue are increased, and the fixing effect is improved; by arranging the porous body 132 between each protruding tooth 121, the biological compatibility and bone growth induction of the porous body 132 are utilized to promote the growth of the vertebral tissue in the porous body 132, realize biological fixation, and thus enhance the overall fixing effect.

[0043] The above design makes the connection between the fusion cage and the vertebral tissue more firm, and can maintain stability even when the patient is moving, which is beneficial to the smooth progress of intervertebral fusion; in the actual use process: the doctor designs the distribution and size of the protruding teeth 121 and the porous body 132 according to the specific situation of the patient's vertebrae before implanting the fusion cage (then a corresponding intervertebral fusion cage is manufactured through 3D printing or the like), so as to achieve the best fixing effect.

[0044] As Figure 1 shown, the first endplate assembly 10 has three mutually perpendicular first, second and third directions; the end surface of the endplate body 11 in the first direction is the bearing contact surface 111, a plurality of protruding teeth 121 are arranged in rows along the second direction and in columns along the third direction on the bearing contact surface 111; wherein, in a column of protruding teeth 121, one porous body 132 is arranged between two adjacent protruding teeth 121, and the porous body 132 is connected with the two adjacent protruding teeth 121 respectively; and / or, in a row of protruding teeth 121, a plurality of protruding teeth 121 are arranged at equal intervals.

[0045] By arranging the protruding teeth 121 in a specific direction on the bearing contact surface 111, an ordered arrangement array is formed, which on the one hand increases the effective area of contact with the vertebrae, and on the other hand ensures uniform distribution of mechanical fixation strength; by providing the porous body 132 between the protruding teeth 121, not only the area of the contact surface is increased, the efficiency of biological fixation is improved, but also the structural stability of the entire bearing contact surface 111 is enhanced through the connection of the porous body 132 and the protruding teeth 121.

[0046] In this way, the contact of the bearing contact surface 111 of the fusion cage with the vertebral tissue is more comprehensive and stable, which is conducive to the long-term success of intervertebral fusion; the actual application scenario is in spinal surgery, especially in cases where intervertebral height restoration and vertebral stability are required. The actual use process is: before implanting the fusion cage, the doctor designs the arrangement direction of the protruding teeth 121 and the position of the porous body 132 according to the scan results of the patient's vertebrae, to ensure the best fitting and fixing effect.

[0047] As shown in Figure 1 , in a row of protruding teeth 121, the porous body 132 between two adjacent protruding teeth 121 protrudes towards the vertebral tissue, and the distance of the protruding end from the bearing contact surface 111 in the first direction is a first distance; the protruding tooth 121 protrudes towards the vertebral tissue, and the distance of the protruding end from the bearing contact surface 111 in the first direction is a second distance; wherein the first distance and the second distance are the same; and / or, the second distance is greater than or equal to 0.5mm and less than or equal to 1.5mm.

[0048] By controlling the protruding degree of the protruding teeth 121 and the porous body 132, the contact depth of the two with the vertebral tissue is ensured to be consistent, thereby achieving a balance between mechanical fixation and biological fixation; such design can not only ensure the initial stability of the fusion cage, but also promote long-term bone fusion, avoiding stress concentration and fusion failure due to inconsistent fixation depth; the above design enables the intervertebral fusion cage to provide sufficient stability in the short term after implantation, while promoting bone tissue growth in the long term and achieving permanent fixation.

[0049] As shown in Figure 1 , in a row of protruding teeth 121, the distance between two adjacent protruding teeth 121 is greater than or equal to 0.8mm and less than or equal to 3mm; and / or, in a row of protruding teeth 121, the distance between two adjacent protruding teeth 121 is greater than or equal to 0.8mm and less than or equal to 3mm.

[0050] By reasonably controlling the distance between the protruding teeth 121, both sufficient mechanical fixation strength and sufficient space for the porous body 132 to play a biological fixation role are ensured; too small distance between the protruding teeth 121 will lead to excessive mechanical fixation, affecting the biological fixation effect; too large distance will weaken the mechanical fixation strength; in this way, after the intervertebral fusion cage is implanted, the growth of bone tissue is promoted on the basis of ensuring short-term stability, and long-term stable fixation is realized. The actual use process is: before implanting the fusion cage, the doctor adjusts the distance between the protruding teeth 121 according to the actual situation of the patient's vertebrae, to ensure the best fixation effect and bone growth space.

[0051] As shown in Figure 1 , the protruding teeth 121 have the same external shape as the porous body 132; and / or, the protruding teeth 121 are one of a trapezoidal shape, a pyramid shape and a prism shape; and / or, the protruding teeth 121 protrude towards the vertebral tissue, and the distance of the protruding end from the bearing contact surface 111 in the first direction is a second distance, which is greater than or equal to 0.5 mm and less than or equal to 1.5 mm; and / or, the distance between the two ends of the protruding teeth 121 in the second direction is greater than or equal to 0.2 mm and less than or equal to 1 mm; and / or, the distance between the two ends of the protruding teeth 121 in the third direction is greater than or equal to 0.2 mm and less than or equal to 1 mm; and / or, the porous body 132 includes a plurality of cross-network arranged connecting columns 133, one end of one connecting column 133 is connected with another connecting column 133 or protruding tooth 121 respectively, and the other end of one connecting column 133 is connected with another connecting column 133 or another protruding tooth 121 respectively, so that any end of the connecting column 133 is not suspended.

[0052] By designing the protruding teeth 121 as a trapezoidal shape, a pyramid shape or a prism shape, and the same external shape as the porous body 132, both the contact area with the vertebral tissue and the stability of the structure are ensured; the cross-network connecting columns 133 inside the porous body 132 can further enhance the strength of the structure, while providing a good bone growth path, avoiding the instability of the isolated porous structure 13.

[0053] The above design makes the intervertebral fusion cage provide sufficient stability in the short term after implantation, while promoting the growth of bone tissue in the long term, realizing permanent fixation; the application scenario is in spinal surgery, especially in cases where intervertebral fusion is required, this design can better adapt to the growth needs of the vertebral tissue, improve the success rate of fusion; the actual use process is: before implanting the fusion cage, the doctor adjusts the shape of the protruding teeth 121 and the structure of the porous body 132 according to the specific situation of the patient's vertebrae, to achieve the best fixation effect and bone growth environment.

[0054] In addition, it should be noted that: Figure 3 andFigure 4 As shown in the comparison Figure 3 and Figure 4 the structure of the connecting column 133 in the middle, it can be found that Figure 3 either end of the connecting column 133 in the middle is not suspended, while Figure 4 one end of some connecting columns 133 in the middle is suspended, and the present application finds in actual use and tests that Figure 3 the connecting column 133 in the middle Figure 4 the connecting column 133 in the middle can obviously improve the connection strength with the vertebral tissue in the subsequent process and reduce the damage to the vertebral tissue, Figure 3 the plurality of connecting columns 133 in the middle form a cross-fixing structure, which can improve the overall strength and increase the bone contact area; and Figure 4 the suspended end of the connecting column 133 in the middle may damage the growing vertebral tissue, which is not conducive to the subsequent postoperative rehabilitation of the patient; therefore, Figure 3 the connecting column 133 in the middle Figure 4 the actual use effect of the connecting column 133 in the middle is better.

[0055] As shown in Figure 1 and Figure 2 the protruding tooth 121 is taken in a plane parallel to the first direction to obtain a cross section of the protruding tooth 121, and the shape of the cross section is a triangle or a trapezoid; and / or, when the protruding tooth 121 is a prism, the protruding tooth 121 is taken in a plane parallel to the first direction to obtain a cross section of the protruding tooth 121, and the shape of the cross section is a triangle or a trapezoid, one side of the two sides of the triangle or the two sides of the trapezoid has an included angle with the first direction, the included angle is a first included angle, the first included angle is greater than or equal to 0° and less than or equal to 60°.

[0056] By controlling the cross-sectional shape of the protruding tooth 121, especially when it is a prism, by adjusting the included angle of the triangular or trapezoidal side of the cross section with the first direction, the contact mode of the protruding tooth 121 with the vertebral tissue can be optimized, and the mechanical fixation effect can be improved; this design can ensure that the protruding tooth 121 can better embed into the vertebral tissue during implantation, and at the same time, when bearing pressure, it can disperse stress and reduce damage to the vertebral tissue.

[0057] The actual implementation effect of the above design is that after the intervertebral fusion cage is implanted, sufficient stability can be provided in a short period of time, and the pressure on the vertebral tissue is reduced, which is beneficial to the smooth progress of intervertebral fusion; the actual application scenario is in spinal surgery, especially in cases that require intervertebral fusion, this design can better adapt to the growth characteristics of the vertebral tissue and improve the fusion success rate; the actual use process is that before implanting the fusion cage, the doctor adjusts the cross-sectional shape and the included angle of the protruding tooth 121 according to the specific situation of the patient's vertebrae to achieve the best fixation effect and reduce the pressure on the vertebral tissue.

[0058] As shown in Figures 3 to 10 , the porosity of the porous structure 13 is greater than or equal to 20% and less than or equal to 80%; and / or, the diameter of the hollow hole 131 is greater than or equal to 0.2mm and less than or equal to 1.5mm; and / or, the volume ratio of the porous structure 13 in the whole is greater than or equal to 20% and less than or equal to 80% when the porous structure 13 and the anti-back tooth structure 12 are regarded as a whole.

[0059] By controlling the porosity of the porous structure 13 and the diameter of the hollow hole 131, as well as the volume ratio of the porous structure 13 in the whole anti-back tooth structure 12, the biological fixation effect can be optimized to promote the growth and fusion of bone tissue; too high porosity will lead to a decrease in structural strength, and too low porosity will not be conducive to the ingrowth of bone tissue; too large diameter of the hollow hole 131 may lead to poor bone growth, and too small diameter may hinder the ingrowth of bone tissue.

[0060] The actual implementation effect of the above design is that after the intervertebral fusion cage is implanted, a good bone growth environment can be provided on the basis of ensuring the structural strength to promote the rapid growth and fusion of bone tissue; the actual application scenario is in spinal surgery, especially in cases where intervertebral fusion is required, and this design can better adapt to the growth needs of vertebral tissue to improve the fusion success rate; the actual use process is that before implanting the fusion cage, the doctor designs the porosity of the porous structure 13, the diameter of the hollow hole 131, and the volume ratio of the porous structure 13 according to the actual situation of the patient's vertebrae to ensure the best biological fixation effect.

[0061] It should be noted that in one specific embodiment of the present application, porosity is a physical quantity that describes the proportion of pores (i.e. the part of space not filled by solid) in a material. Porosity is a dimensionless parameter, usually expressed as a percentage, used to quantify the internal void space of a material. The following are several main aspects of porosity in the present application: 1. Definition: The porosity in the present application refers to the ratio of the volume of internal voids to the total volume of the material. In other words, porosity is a parameter that measures the space not filled by solid within the material; 2. Calculation method: Porosity can be calculated by the following formula: Porosity (%) = (Void Volume / Total Volume) x 100%. Where, Void Volume refers to the space not filled by solid within the material, and Total Volume refers to the volume of the entire material; 3. Influencing factors of porosity: Porosity depends on the type, structure and preparation process of the material. For example, porous materials (such as foams, honeycomb structures, etc.) usually have high porosity.

[0062] It should be noted that as shown in Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 andFigure 10 As shown in Embodiment One to Embodiment Six of the present application, the internal morphology of the porous structure 13 has various designs, Figures 5 to 10 Six embodiments are listed, the porosity of the porous structure 13 is maintained at 20%~80%, and the pore size is controlled at 0.2mm~1.5mm.

[0063] As Figure 1 shown, the bearing contact surface 111 has a groove, and a part of the porous structure 13 is arranged in the groove, which is the first part 134, and the first part 134 is limited in cooperation with the inner wall of the groove.

[0064] By setting the groove on the bearing contact surface 111 and embedding the first part 134 of the porous structure 13 in it, it can ensure the close contact of the porous structure 13 with the vertebral tissue, and at the same time provide stable limiting action to avoid displacement of the porous structure 13 during implantation. The above design makes the intervertebral fusion cage after implantation, the porous structure 13 can accurately contact with the vertebral tissue, promote the growth and fusion of bone tissue, and at the same time ensure the stability of the structure. The actual application scenario is in the spine surgery, especially in the cases that need to be fused between the vertebrae, this design can better adapt to the growth needs of the vertebral tissue, improve the fusion success rate. The design process is: before implanting the fusion cage, the doctor corresponds to the number and position of the grooves on the bearing contact surface 111 to ensure that the first part 134 of the porous structure 13 can be accurately embedded to achieve the best fixation effect and bone growth environment.

[0065] As Figure 1 shown, the end of the first part 134 towards the vertebral tissue is flush with the bearing contact surface 111, so that the first part 134 and the bearing contact surface 111 jointly abut against the vertebral tissue.

[0066] By ensuring the flushness of the first part 134 and the bearing contact surface 111, the contact area with the vertebral tissue can be maximized, and at the same time the fit of the porous structure 13 with the vertebral tissue is ensured, and the biological fixation effect is improved. In this way, after the intervertebral fusion cage is implanted, it is more comprehensive to contact with the vertebral tissue, which is conducive to the growth and fusion of bone tissue, and at the same time ensures the stability of the structure. The actual application scenario is in the spine surgery, especially in the cases that need to be fused between the vertebrae, this design can better adapt to the growth needs of the vertebral tissue, improve the fusion success rate. The actual use process is: before implanting the fusion cage, the doctor checks the flushness of the first part 134 and the bearing contact surface 111 to ensure that it can fully contact with the vertebral tissue after implantation to achieve the best fixation effect and bone growth environment.

[0067] As Figure 1As shown, the shape of at least part of the bearing contact surface 111 is adapted to the shape of the end of the vertebral tissue towards the bearing contact surface 111, so that at least part of the bearing contact surface 111 is in close contact with the vertebral tissue; and / or, the first endplate assembly 10 has three mutually perpendicular first, second and third directions; the elastic support assembly 30 includes a plurality of elastic bodies 31, which are arranged at intervals along the second and third directions; the elastic bodies 31 extend in a wave shape along the first direction to form a wave plate structure, which generates elastic force through deformation; and / or, the first endplate assembly 10 has three mutually perpendicular first, second and third directions; the middle part of the intervertebral fusion cage has a through space 40, which penetrates the endplate body 11 of the first endplate assembly 10 and the endplate body 11 of the second endplate assembly 20; wherein, along the first direction, the projection of the through space 40 is arranged at intervals with the projection of the elastic support assembly 30, the projection of the anti-back tooth structure 12 and the projection of the porous structure 13, respectively; the through space 40 is used to accommodate vertebral tissue.

[0068] By adapting the shape of the bearing contact surface 111 to the structure of the vertebral tissue (specific structure detected by scanning and other medical means), the close contact of the fusion cage with the vertebral tissue can be ensured, and the effect of mechanical fixation and biological fixation can be improved; the wave plate structure of the elastic support assembly 30 can deform moderately when bearing pressure, providing a buffering effect and reducing the pressure on the vertebral tissue, while ensuring the stable support of the fusion cage; the design of the through space 40 can accommodate vertebral tissue, providing space for bone growth, and also helping to disperse stress and avoid excessive local pressure.

[0069] The actual implementation effect of the above design is that after the intervertebral fusion cage is implanted, it can provide sufficient stability in the short term, while promoting bone growth and fusion in the long term, reducing pressure on the vertebral tissue, avoiding bone destruction and improving the success rate of intervertebral fusion; the actual application scenario is in spinal surgery, especially in treatments requiring intervertebral height restoration and vertebral stability, this design can better adapt to the physiological characteristics of vertebral tissue and improve the success rate of fusion; the actual use process is that before implanting the fusion cage, the doctor adjusts the shape of the bearing contact surface 111, the distribution of the elastic bodies 31 of the elastic support assembly 30 and the size of the through space 40 according to the specific situation of the patient's vertebrae to ensure the best fixation effect and bone growth environment.

[0070] It is worth noting that in one specific embodiment of the present application, the design of the elastic bodies 31 of the elastic support assembly 30 is not limited to Figure 1 the wave plate structure in the example.

[0071] It should be noted that: in a specific embodiment of the present application, the second end plate assembly 20 also includes an end plate body 11, a tooth preventing structure 12 and a porous structure 13, the convex teeth 121, the bearing contact surface 111 and the porous body 132 are the same as the first end plate assembly 10.

[0072] The present application also provides an intervertebral fusion cage manufacturing method for manufacturing the above-mentioned intervertebral fusion cage, the intervertebral fusion cage manufacturing method comprising the following steps: obtaining the intervertebral fusion cage by 3D printing and / or cutting processing; processing the shape of at least part of the bearing contact surface 111 to be matched with the shape of the end of the vertebral tissue facing the bearing contact surface 111, so that at least part of the bearing contact surface 111 is matched with the vertebral tissue; processing to obtain a plurality of convex teeth 121 arranged on the bearing contact surface 111, processing to obtain a plurality of porous bodies 132, and making the two ends of the porous body 132 located between two adjacent convex teeth 121 connected with the two adjacent convex teeth 121 respectively.

[0073] By 3D printing and / or cutting processing technology, the intervertebral fusion cage with complex geometric shape and structure can be accurately manufactured, ensuring its adaptability and fixation effect with the vertebral tissue; the shape of the bearing contact surface 111, the distribution of the convex teeth 121 and the connection of the porous body 132 are all for realizing better mechanical fixation and biological fixation effect, and improving the success rate of intervertebral fusion. The actual implementation effect is that the intervertebral fusion cage can be designed and manufactured flexibly according to different vertebral tissues, has stable structure, good adaptability with the vertebral tissue, can provide effective mechanical and biological fixation, reduce postoperative complications and improve the success rate of intervertebral fusion. The actual use process is: according to the detection and scanning data of the patient's vertebral tissue provided by the doctor, the intervertebral fusion cage matched with the patient's vertebral tissue is accurately manufactured by using 3D printing and / or cutting processing technology, ensuring that the best fixation effect and bone growth environment can be provided in the operation.

[0074] Now the specific working process and principle of an embodiment of the present application are described in detail as follows:

[0075] The anti-retreating fusion cage comprises a first endplate assembly 10, an elastic support assembly 30 and a second endplate assembly 20; the first endplate assembly 10 comprises a protruding tooth 121, a bearing contact surface 111 and a porous body 132; the bearing contact surface 111 is matched with the vertebral body endplate (i.e. the vertebral tissue), which can maximize the contact area, keep the prosthesis (i.e. the intervertebral fusion cage) uniform stress, and improve the service life of the prosthesis; the protruding tooth 121 can be inserted into the vertebral body endplate, the protruding tooth 121 forms a matrix, and is matched with the porous body 132 respectively; the protruding tooth 121 can ensure sufficient mechanical strength to prevent the intervertebral fusion cage from loosening or falling out due to stress damage; the porous body 132 can grow into bone at the contact surface, further improving the stability of long-term connection, and as the bone grows, the connection strength of the position of the porous body 132 gradually improves, thereby reducing the stress of the protruding tooth 121 and further improving the service life of the intervertebral fusion cage.

[0076] The elastic support assembly 30 can reduce the overall stiffness of the intervertebral fusion cage, so that the first endplate assembly 10 and the second endplate assembly 20 can be self-adaptively adjusted to a certain extent. Compared with the existing high-stiffness fusion cage structure which cannot be self-adaptively adjusted, the present application can adjust the intervertebral fusion cage according to different bone conditions of patients, so that the stiffness of the intervertebral fusion cage can match a variety of patients, and the abnormal conditions such as vertebral body endplate collapse of the vertebral tissue of osteoporosis patients can be effectively prevented; the working principle of the second endplate assembly 20 is the same as that of the first endplate assembly 10.

[0077] The protruding tooth 121 is designed as a prismatic structure with a triangular or trapezoidal cross section, the height (the size in the first direction) is controlled to be 0.5mm-1.5mm, the width and / or thickness (the size in the second direction and / or the third direction) is controlled to be 0.2mm-1mm, the distance between two adjacent protruding teeth 121 is kept to be 0.8mm-3mm, and the inclination angle of the protruding tooth 121 relative to the bearing contact surface 111 is controlled to be 30°-90°; the porosity of the porous structure 13 is kept to be 20%-80%, and the pore size is controlled to be 0.2-1.5mm; the volume ratio of the porous structure 13 in the whole is kept to be in the range of 20%-80% when the porous structure 13 and the anti-retreating tooth structure 12 are regarded as a whole.

[0078] The protruding tooth 121 and the porous body 132 are manufactured by selecting additive manufacturing (such as 3D printing forming technology, integrated injection molding technology, etc.) and subtractive manufacturing (such as cutting and drilling processing, etc.); in order to better maintain the mechanical properties of the anti-retreating tooth structure 12 and the porous structure 13, computer mechanical calculation and simulation analysis of the anti-retreating tooth structure 12 and the porous structure 13 are required to achieve the best effect.

[0079] The intervertebral fusion device provided by the application can be used in actual application, CT data of a patient can be scanned first, specific vertebral tissue data shown in the CT data of the patient is measured, parameters such as bone density and shape and size of the vertebral endplate surface are estimated, specific parameters of the anti-back tooth structure 12, the porous structure 13, the endplate body 11 and the elastic body 31 are designed according to different conditions of the patient, and the corresponding intervertebral fusion device is formed after the specific parameters are processed.

[0080] In summary, the application provides an intervertebral fusion device and a manufacturing method thereof. The anti-back tooth structure 12 can be inserted into the vertebral tissue, the connection strength with the vertebral tissue is ensured, and the loosening or dislocation of the intervertebral fusion device caused by stress damage is prevented. The bone tissue grown from the vertebral tissue can grow into the porous structure 13, the contact area with the vertebral tissue is increased, the connection strength and long-term stability of the intervertebral fusion device and the vertebral tissue are further improved, the mechanical strength of the vertebral tissue and the porous structure 13 is gradually improved along with the growth of the bone tissue, the stress borne by the anti-back tooth structure 12 is further reduced, and the service life of the intervertebral fusion device is further improved. The elastic support assembly 30 is made of elastic material, the elastic force generated by the elastic support assembly 30 can support the first endplate assembly 10 and the second endplate assembly 20 to abut against the vertebral tissue, the rigidity of the intervertebral fusion device is reduced, the first endplate assembly 10 and the second endplate assembly 20 can be self-adaptively adjusted to a certain extent, the intervertebral fusion device can be adjusted according to different bone conditions of the patient, the rigidity of the intervertebral fusion device can be matched with various patients, and the abnormal conditions such as collapse of the vertebral endplate of the vertebral tissue of the osteoporosis patient can be effectively prevented. The application solves the problems of low contact area between the intervertebral fusion device and the vertebral bone in the prior art, and the postoperative prosthesis dislocation or loosening, endplate bone damage and poor fusion efficiency. The application has simple structure, low cost, is convenient for processing, production and installation, and is suitable for large-scale popularization and use.

[0081] It is to be noted that the terms used herein are only intended to describe specific embodiments and are not intended to limit the example embodiments according to the present application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise, and it should also be understood that the terms "comprise" and / or "include" as used in the specification mean the presence of features, steps, operations, devices, components and / or combinations thereof.

[0082] The foregoing is considered as illustrative only of the principles of the application. Further, since numerous modifications and changes will readily occur to those skilled in the art, it is not desired to limit the application to the exact construction and practice described. Accordingly, all such variations are intended to be included within the scope of the present application as defined in the following claims, along with full equivalents thereof.

[0083] In the description of the present application, it is to be understood that the orientation or positional relationships indicated by terms such as "front", "back", "up", "down", "left", "right", "lateral", "vertical", "horizontal", "top", "bottom", and the like are generally based on the orientation or positional relationships shown in the drawings, and are merely intended to facilitate the description and simplify the description, and do not indicate or imply that the device or element referred to must have a particular orientation or be constructed and operated in a particular orientation, and therefore cannot be construed as limiting the scope of protection of the present application. The orientation terms "inner", "outer" refer to the inner and outer relative to the contour of the components themselves.

[0084] For the convenience of description, spatial relative terms such as "above", "upper", "top", "up", "lower", "bottom", and the like can be used herein to describe the spatial relationship of one device or feature to another device or feature as shown in the drawings. It should be understood that the spatial relative terms are intended to include different orientations of the device in use or operation in addition to the orientation of the device described in the drawings. For example, if the device in the drawings is turned over, the device described as "above" or "on" the other device or structure will be positioned "below" or "under" the other device or structure. Thus, the exemplary term "above" can include both the "above" and "below" orientations. The device can also be positioned in other different ways (rotated 90 degrees or in other orientations) and the spatial relative descriptions used herein will be interpreted accordingly.

[0085] In addition, it should be noted that the use of the terms "first", "second", and the like do not have a special meaning, and are merely used to distinguish the corresponding components, and therefore cannot be construed as limiting the scope of protection of the present application.

[0086] The above merely provides the preferred embodiments of the present application, and is not used to limit the present application. For those skilled in the art, the present application can have various modifications and changes. Any modifications, equivalent replacements, improvements, etc. made within the principles and technical scope of the present application shall fall into the scope of the present application.

Claims

1. An interbody fusion device, characterized in that, include: The system comprises a first endplate assembly (10), a second endplate assembly (20), and an elastic support assembly (30); the first endplate assembly (10) and the second endplate assembly (20) have the same structure; the two ends of the elastic support assembly (30) are respectively connected to the first endplate assembly (10) and the second endplate assembly (20), and the elastic support assembly (30) is made of elastic material, the elastic force of which is used to support the first endplate assembly (10) and the second endplate assembly (20) to abut against the vertebral tissue respectively; wherein, the first endplate assembly (10) includes an endplate body (11), an anti-retraction tooth structure (12), and a porous structure (13), the endplate body (10) and the second endplate assembly (20) are respectively connected to the first endplate assembly (10) and the second endplate assembly (20), and the elastic support assembly (30) is made of elastic material, the elastic force of which is used to support the first endplate assembly (10) and the second endplate assembly (20) to abut against the vertebral tissue respectively; wherein, the first endplate assembly (10) includes an endplate body (11), an anti-retraction tooth structure (12), and a porous structure (13), ... an elastic support assembly (30), the first endplate assembly (1 One end face of the plate (11) is connected to the elastic support component (30), and the other end face is a bearing contact surface (111), which is used to abut against the vertebral tissue; the anti-retraction tooth structure (12) and the porous structure (13) are respectively disposed on the bearing contact surface (111); the anti-retraction tooth structure (12) protrudes from the bearing contact surface (111) and is used to fix and connect with the vertebral tissue; the porous structure (13) has a hollow hole (131) inside, which is used to allow a part of the growing vertebral tissue to extend into the porous structure (13) to fix and connect with the porous structure (13); The anti-retraction tooth structure (12) includes a plurality of protruding teeth (121), which are spaced apart on the bearing contact surface (111); the porous structure (13) includes a plurality of porous bodies (132), which have the hollow holes (131) inside, and at least one porous body (132) is disposed between two adjacent protruding teeth (121); The porous body (132) includes a plurality of cross-shaped connecting posts (133), one end of each connecting post (133) is connected to another connecting post (133) or the protruding tooth (121), and the other end of each connecting post (133) is connected to another connecting post (133) or the protruding tooth (121), so that neither end of the connecting post (133) is suspended. The bearing contact surface (111) has a slot, and a part of the porous structure (13) is disposed in the slot. This part is the first part (134), and the first part (134) is in a limiting fit with the inner wall of the slot.

2. The interbody fusion device according to claim 1, characterized in that, The first end plate assembly (10) has three mutually perpendicular directions: a first direction, a second direction, and a third direction; the end face of the end plate body (11) in the first direction is the bearing contact surface (111), and a plurality of protruding teeth (121) are arranged in rows along the second direction and in columns along the third direction on the bearing contact surface (111); wherein, in a column of protruding teeth (121), a porous body (132) is disposed between two adjacent protruding teeth (121), and the porous body (132) is connected to two adjacent protruding teeth (121) respectively; and / or, in a row of protruding teeth (121), a plurality of protruding teeth (121) are equidistantly spaced.

3. The interbody fusion device according to claim 2, characterized in that, In a row of protruding teeth (121), the porous body (132) located between two adjacent protruding teeth (121) protrudes toward the vertebral tissue, and the distance of the protruding end relative to the bearing contact surface (111) along the first direction is a first distance; the protruding teeth (121) protrude toward the vertebral tissue, and the distance of the protruding end relative to the bearing contact surface (111) along the first direction is a second distance; wherein, the first distance and the second distance are the same; and / or, the second distance is greater than or equal to 0.5 mm and less than or equal to 1.5 mm.

4. The interbody fusion device according to claim 2, characterized in that, In a column of the protruding teeth (121), the distance between two adjacent protruding teeth (121) is greater than or equal to 0.8 mm and less than or equal to 3 mm; and / or, in a row of the protruding teeth (121), the distance between two adjacent protruding teeth (121) is greater than or equal to 0.8 mm and less than or equal to 3 mm.

5. The interbody fusion device according to claim 2, characterized in that, The protruding teeth (121) have the same external shape as the porous body (132); And / or, the protruding tooth (121) is one of a trapezoidal, pyramidal, and prismatic shape; And / or, the protruding tooth (121) protrudes toward the vertebral tissue, and the distance of the protruding end along the first direction relative to the bearing contact surface (111) is the second distance, the second distance being greater than or equal to 0.5 mm and less than or equal to 1.5 mm; And / or, the distance between the two ends of the protruding tooth (121) along the second direction is greater than or equal to 0.2 mm and less than or equal to 1 mm; And / or, the distance between the two ends of the protruding tooth (121) along the third direction is greater than or equal to 0.2 mm and less than or equal to 1 mm.

6. The interbody fusion device according to claim 5, characterized in that, The protruding tooth (121) is cut with a plane parallel to the first direction to obtain a cross section of the protruding tooth (121), the shape of the cross section being a triangle or a trapezoid; and / or, when the protruding tooth (121) is prism-shaped, the protruding tooth (121) is cut with a plane parallel to the first direction to obtain a cross section of the protruding tooth (121), the shape of the cross section being a triangle or a trapezoid, one of the two sides of the triangle or one of the two legs of the trapezoid having an angle with the first direction, the angle being a first angle, the first angle being greater than or equal to 0° and less than or equal to 60°.

7. The interbody fusion device according to claim 1, characterized in that, The porosity of the porous structure (13) is greater than or equal to 20% and less than or equal to 80%; and / or the diameter of the hollow hole (131) is greater than or equal to 0.2 mm and less than or equal to 1.5 mm; and / or, the porous structure (13) and the anti-retraction tooth structure (12) are considered as a whole, and the volume ratio of the porous structure (13) in the whole is greater than or equal to 20% and less than or equal to 80%.

8. The interbody fusion device according to claim 1, characterized in that, The end of the first part (134) facing the vertebral tissue is flush with the bearing contact surface (111) so that the first part (134) and the bearing contact surface (111) together abut against the vertebral tissue.

9. The interbody fusion device according to claim 1, characterized in that, The shape of at least a portion of the bearing contact surface (111) is adapted to the shape of one end of the vertebral tissue facing the bearing contact surface (111), so that at least a portion of the bearing contact surface (111) fits against the vertebral tissue; And / or, the first endplate assembly (10) has three mutually perpendicular first directions, second directions and third directions; the elastic support assembly (30) includes a plurality of elastic bodies (31), the plurality of elastic bodies (31) being spaced apart along the second direction and the third direction; the elastic bodies (31) extend in a wave-like manner along the first direction to form a wave plate structure, the wave plate structure generating the elastic force through deformation; And / or, the first endplate assembly (10) has three mutually perpendicular first directions, second directions and third directions; the middle part of the interbody fusion device has a through space (40), the through space (40) through the endplate body (11) of the first endplate assembly (10) and the endplate body (11) of the second endplate assembly (20); wherein, when projected along the first direction onto the same plane perpendicular to the first direction, the projection of the through space (40) is spaced apart from the projection of the elastic support assembly (30), the projection of the anti-retraction structure (12) and the projection of the porous structure (13); the through space (40) is used to accommodate the vertebral tissue.

10. A method for manufacturing an interbody fusion device, characterized in that, The method for manufacturing an interbody fusion device is used to manufacture the interbody fusion device according to any one of claims 1 to 9, and the method for manufacturing an interbody fusion device includes the following steps: The intervertebral fusion device is obtained by 3D printing and / or machining. The shape of at least a portion of the bearing contact surface (111) is adapted to the shape of one end of the vertebral tissue facing the bearing contact surface (111) so that at least a portion of the bearing contact surface (111) fits against the vertebral tissue; Multiple protruding teeth (121) spaced apart on the bearing contact surface (111) are processed to obtain multiple porous bodies (132), and the two ends of the porous body (132) located between two adjacent protruding teeth (121) are respectively connected to the two adjacent protruding teeth (121).

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