Single-cell nerve cell imaging diagnostic apparatus

Abstract

The invention discloses a single-cell nerve cell imaging diagnostic apparatus, and relates to the technical field of diagnostic equipment, the single-cell nerve cell imaging diagnostic apparatus comprises a control shell and a sample placing plate, and also comprises a mounting mechanism arranged on the control shell and used for mounting the sample placing plate, and a uniform distribution mechanism arranged on the mounting mechanism and used for uniformly distributing samples in a sample pool, the mounting mechanism comprises two guide rails which are fixedly connected between the two opposite inner walls of the detection shell and are symmetrically arranged, the two guide rails are slidably connected with a sliding plate, a mounting groove is formed in the side, close to the detection probe and the detection port, of the sliding plate, and insertion grooves are formed in the two opposite inner walls of the mounting hole. According to the single-cell nerve cell imaging diagnostic apparatus disclosed by the invention, through the arrangement of the uniform distribution mechanism, the distribution uniformity of the sample in the sample pool and the elimination of bubbles in the sample are improved, so that the accuracy of single-cell nerve cell imaging diagnosis is improved.

Description

TECHNICAL FIELD

[0001] The application relates to the technical field of diagnostic equipment, in particular to a single-cell nerve cell imaging diagnostic instrument. BACKGROUND

[0002] The single-cell analyzer converts the structure (such as synapses), function (such as electrical activity) and molecular characteristics (such as protein expression) of nerve cells into visual image signals through a technical path of 'labeling-imaging-analysis', and the core principle is to realize the synchronous acquisition of multi-dimensional information at the single-cell scale by using optical, electrical, microfluidic and other technical means, thereby providing precise imaging basis for the pathological mechanism research and early diagnosis of neurological diseases (such as Alzheimer's disease and epilepsy).

[0003] When the single-cell analyzer is used for single-cell nerve cell imaging diagnosis of a detection sample, the detection sample is placed on a glass slide, and then the glass slide is inserted into a detection slot of the body, so that the detection can be automatically realized. Although the operation is simple, when the sample is manually dropped, the cell suspension is prone to uneven distribution, that is, the cell density is high at the edge of the droplet and low at the center, thereby not only leading to low single-cell capture rate, but also easily generating bubbles, causing visual field obstruction, and thus affecting the precision of single-cell nerve cell imaging diagnosis. Therefore, we propose a single-cell nerve cell imaging diagnostic instrument. SUMMARY

[0004] The application aims to provide a single-cell nerve cell imaging diagnostic instrument to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the application provides the following technical scheme: a single-cell nerve cell imaging diagnostic instrument, comprising a control shell and a sample placement plate, one side of the control shell is fixedly connected with a detection shell, the detection shell is connected with a detection probe through a support, the side of the control shell away from the detection shell is provided with a display screen and a detection port, the detection port is hingedly connected with a baffle, the detection shell is provided with a power control key, the sample placement plate is provided with a plurality of sample pools, and the application further comprises a mounting mechanism arranged on the detection shell and used for mounting the sample placement plate, and a uniform distribution mechanism arranged on the mounting mechanism and used for uniformly distributing the samples in the sample pools.

[0006] The mounting mechanism comprises two symmetrically arranged guide rails fixedly connected between two inner walls of the detection shell, a sliding plate slidably connected to the two guide rails, an installation slot formed in a side of the sliding plate close to the detection probe and the detection port, an installation plate slidably connected to the installation slot, an installation hole formed in the installation plate, the installation hole penetratingly arranged on a side close to the detection port, two insertion slots formed in two opposite inner walls of the installation hole, and two sample placing plates matched with the two insertion slots.

[0007] Preferably, the uniform distribution mechanism comprises a first L-shaped plate fixedly connected to a side wall of one of the two guide rails, the first L-shaped plate is arranged close to the detection port, and a uniform distribution rod is fixedly connected to a side of the first L-shaped plate close to the sliding plate, one end of the uniform distribution rod away from the first L-shaped plate is fixedly connected with a tapered rod, and a plurality of uniform distribution holes are formed in a side of the installation plate close to the tapered rod, each uniform distribution hole is arranged at the same height as the tapered rod.

[0008] Preferably, an avoiding hole is formed in a side of the sliding plate close to the uniform distribution hole, and the tapered rod is slidably connected to the avoiding hole.

[0009] Preferably, the installation plate is provided with a conversion assembly for multi-directional position conversion of the sample placing plate, the conversion assembly comprises a plurality of conversion plates fixedly connected to a side of the installation plate close to the sliding plate, the two opposite sides of each conversion plate are provided with inclined surfaces, a conversion rod is fixedly connected to a side of the installation slot close to the conversion plate, and the conversion rod is located between two adjacent conversion plates.

[0010] Preferably, the extension assembly comprises two symmetrically arranged second L-shaped plates fixedly connected to a side of the sliding plate away from the first L-shaped plate, two extension blocks are connected to a side of each second L-shaped plate close to the installation plate through a reset assembly, two extension holes are formed in a side of the sliding plate close to the second L-shaped plate, an extension rod is fixedly connected between two opposite inner walls of the two extension holes, the two extension blocks are slidably connected to the extension rod, two first springs are respectively sleeved on the side walls of the two extension rods, and the two ends of the two first springs are respectively connected with the extension blocks and the inner walls of the extension holes.

[0011] Preferably, the reset assembly comprises a reset tube fixedly connected to the second L-shaped plate on the side close to the telescopic block, the reset tube is connected with a reset plate through a guide assembly, the reset plate is fixedly connected with a reset rod on the side close to the telescopic block, the reset rod is connected with the telescopic block on the end away from the reset plate, and the reset plate is fixedly connected with a second spring on the side away from the reset rod, and the second spring is connected with the bottom wall of the reset tube on the end away from the reset plate.

[0012] Preferably, the guide assembly comprises two symmetrically arranged guide holes formed in the side wall of the reset tube, and the two guide holes are slidably connected with guide plates, and the opposite ends of the two guide plates are connected with the reset plate.

[0013] Preferably, the fixing assembly comprises a plurality of fixing holes formed in the installation plate on the side close to the detection probe, each fixing hole is located on the two sides of the installation hole, each fixing hole is slidably connected with a T-shaped fixing rod, the side wall of each T-shaped fixing rod is sleeved with a third spring, and the two ends of each third spring are connected with the side wall of the T-shaped fixing rod and the installation plate, respectively, the end away from the installation plate of each T-shaped fixing rod is rotatably connected with a rotating ball, and the two guide rails are provided with a driving assembly for driving each T-shaped fixing rod located on the same side.

[0014] Preferably, the driving assembly comprises a plurality of U-shaped plates fixedly connected to the guide rail on the side close to the first L-shaped plate, the end away from the guide rail of each U-shaped plate is located above the installation plate, and a driving strip-shaped plate is fixedly connected, and the side close to the detection port of the driving strip-shaped plate is fixedly connected with an inclined plate.

[0015] Preferably, the moving assembly comprises a lead screw rotatably connected between the two opposite inner walls of the detection shell, the lead screw is located between the two guide rails and is threadedly connected with a moving plate, one end of the moving plate is connected with the side away from the detection port of the sliding plate, the inner wall of the side away from the control shell of the detection shell is fixedly connected with a motor, the output end of the motor is fixedly connected with a first bevel gear, the side wall of the lead screw is fixedly connected with a second bevel gear, and the second bevel gear and the first bevel gear are arranged in meshing relationship.

[0016] Compared with the prior art, the present application has the following advantages:

[0017] The single-cell nerve cell imaging diagnostic instrument of the present application is provided with a uniform distribution mechanism, which, under the cooperation of a transformation assembly and a telescopic assembly, moves the sample in the sample pool reciprocally in the horizontal and vertical directions, so as to utilize the reciprocating horizontal and vertical shaking effect, improve the uniformity of the distribution of the sample in the sample pool and eliminate the bubbles in the sample, thereby reducing the low single-cell capture rate and the occlusion of the field of view caused by the bubbles due to the uneven distribution of the sample, and improving the precision of the single-cell nerve cell imaging diagnosis. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 The whole structure of the present application is shown in the schematic diagram;

[0019] Figure 2 The internal structure of the detection machine shell is shown in the schematic diagram;

[0020] Figure 3 The position relationship between the sample placement plate and the detection probe is shown in the schematic diagram;

[0021] Figure 4 The structure of the moving assembly is shown in the schematic diagram;

[0022] Figure 5 The position relationship between the sample placement plate and the mounting plate is shown in the schematic diagram;

[0023] Figure 6 The structure of the telescopic assembly is shown in the schematic diagram;

[0024] Figure 7 The structure of the conversion assembly is shown in the schematic diagram;

[0025] Figure 8 The structure between the uniform distribution hole and the avoidance hole is shown in the schematic diagram;

[0026] Figure 9 The structure of the driving assembly is shown in the schematic diagram;

[0027] Figure 10 The Figure 6 enlarged view at A;

[0028] Figure 11 The Figure 7 enlarged view at B.

[0029] In the figure: 101, control shell; 102, detection shell; 103, display screen; 104, detection port; 105, baffle; 106, detection probe; 107, power control key; 108, sample placement plate; 109, sample pool; 201, guide rail; 202, sliding plate; 203, mounting groove; 204, mounting plate; 205, mounting hole; 206, slot; 301, first L-shaped plate; 302, uniform distribution rod; 303, tapered rod; 304, uniform distribution hole; 305, avoidance hole; 401, conversion plate; 402, inclined surface; 403, conversion rod; 501, second L-shaped plate; 502, expansion block; 503, expansion hole; 504, expansion rod; 505, first spring; 601, reset tube; 602, reset plate; 603, reset rod; 604, second spring; 701, guide hole; 702, guide plate; 801, fixing hole; 802, T-shaped fixing rod; 803, third spring; 804, rotating ball; 901, U-shaped plate; 902, driving strip-shaped plate; 903, inclined plate; 1001, lead screw; 1002, moving plate; 1003, second bevel gear; 1004, motor; 1005, first bevel gear. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0031] Embodiment 1

[0032] Please refer to Figures 1-11 , a single cell nerve cell imaging diagnostic instrument in the figure, including control shell 101 and sample placement plate 108, one side of control shell 101 is fixedly connected with detection shell 102, detection shell 102 is connected with detection probe 106 through support, the side of control shell 101 away from detection shell 102 is provided with display screen 103 and detection port 104, detection port 104 is hingedly connected with baffle 105, detection shell 102 is provided with power control key 107, sample placement plate 108 is provided with a plurality of sample pools 109, further including mounting mechanism arranged in detection shell 102 for mounting sample placement plate 108 and uniform distribution mechanism arranged in mounting mechanism for uniformly distributing samples in sample pool 109;

[0033] The mounting mechanism comprises two mutually symmetrical guide rails 201 fixedly connected between two inner walls of the detection shell 102, two guide rails 201 are slidably connected with a sliding plate 202, the sliding plate 202 is provided with a mounting groove 203 on the side close to the detection probe 106 and the detection port 104, the mounting groove 203 is slidably connected with a mounting plate 204, the mounting plate 204 is provided with a mounting hole 205, the mounting hole 205 is provided with a slot 206 on the two opposite inner walls, the two slots 206 are matched with the sample placing plate 108, the mounting plate 204 is provided with a fixing assembly for fixing the sample placing plate 108, the sliding plate 202 is provided with an expansion assembly for expanding the sample placing plate 108 during uniform distribution, and the detection shell 102 is provided with a moving assembly for moving the sample placing plate 108;

[0034] It should be explained here that: through the setting of the mounting mechanism, the installation of the sample placing plate 108 and the detection of the sample in the sample pool 109 are realized.

[0035] Please refer to Figures 1-9 , the uniform distribution mechanism in the drawing comprises a first L-shaped plate 301 fixedly connected to one side wall of the two guide rails 201, the first L-shaped plate 301 is arranged close to the detection port 104, and a uniform distribution rod 302 is fixedly connected to the side close to the sliding plate 202, one end of the uniform distribution rod 302 away from the first L-shaped plate 301 is fixedly connected with a tapered rod 303, a plurality of uniform distribution holes 304 are arranged at equal intervals on the side of the mounting plate 204 close to the tapered rod 303, and each uniform distribution hole 304 is arranged at the same height as the tapered rod 303.

[0036] It should be explained here that: through the setting of the uniform distribution mechanism, under the cooperation of the transformation assembly and the expansion assembly, the sample in the sample pool 109 is moved reciprocally in the horizontal and vertical directions, so that the uniformity of the distribution of the sample in the sample pool 109 and the elimination of bubbles in the sample are improved by the reciprocating horizontal and vertical shaking, thereby reducing the low single-cell capture rate caused by uneven distribution of the sample and the shielding of the field of view by the bubbles, and the precision of single-cell neural cell imaging diagnosis is improved.

[0037] Please refer to Figure 8 , the sliding plate 202 is provided with an avoiding hole 305 on the side close to the uniform distribution hole 304, and the tapered rod 303 is slidably connected to the avoiding hole 305.

[0038] It should be explained here that: through the setting of the avoiding hole 305, a moving space is provided for the movement of the tapered rod 303 after the sample is shaken.

[0039] Please refer to Figure 7 and Figure 11The mounting plate 204 in the figure is provided with a transformation assembly for multi-directional position transformation of the sample placement plate 108, the transformation assembly comprises a plurality of equidistantly arranged transformation plates 401 fixedly connected to one side of the mounting plate 204 close to the sliding plate 202, opposite sides of each transformation plate 401 are provided with inclined surfaces 402, and the mounting groove 203 is fixedly connected with a transformation rod 403 on the side close to the transformation plate 401, the transformation rod 403 is located between two adjacent transformation plates 401;

[0040] It should be noted that, through the transformation assembly, the sample placement plate 108 is subjected to reciprocating longitudinal movement and reciprocating transverse movement, so that the shaking effect of the sample in the sample pool 109 is improved.

[0041] Please refer to Figure 6 and Figure 10 The telescopic assembly in the figure comprises two second L-shaped plates 501 fixedly connected to the sliding plate 202 away from the first L-shaped plate 301, the two second L-shaped plates 501 are symmetrically arranged, the two second L-shaped plates 501 are connected with telescopic blocks 502 through reset assemblies on the side close to the mounting plate 204, the sliding plate 202 is provided with two telescopic holes 503 on the side close to the second L-shaped plate 501, the two telescopic holes 503 are fixedly connected with telescopic rods 504 between the opposite inner walls, the two telescopic blocks 502 are slidingly connected to the telescopic rods 504, and the two telescopic rods 504 are respectively sleeved with two first springs 505, and the two ends of the two first springs 505 are connected with the telescopic blocks 502 and the inner walls of the telescopic holes 503 respectively.

[0042] It should be noted that, through the telescopic assembly, the longitudinal movement of the mounting plate 204 is provided with a guiding and resetting function.

[0043] Please refer to Figure 6 and Figure 10 The reset assembly in the figure comprises a reset tube 601 fixedly connected to the second L-shaped plate 501 on the side close to the telescopic block 502, the reset tube 601 is connected with a reset plate 602 through a guiding assembly, the reset plate 602 is fixedly connected with a reset rod 603 on the side close to the telescopic block 502, one end of the reset rod 603 away from the reset plate 602 is connected with the telescopic block 502, the reset plate 602 is fixedly connected with a second spring 604 on the side away from the reset rod 603, and one end of the second spring 604 away from the reset plate 602 is connected with the bottom wall of the reset tube 601.

[0044] It should be noted that, through the reset assembly, the transverse movement of the mounting plate 204 is provided with a resetting function.

[0045] Please refer to Figure 6 and Figure 10The guiding assembly in the figure comprises two symmetrically arranged guiding holes 701 formed in the sidewall of the reset tube 601, two guiding plates 702 are slidably connected with the guiding holes 701, and the opposite ends of the two guiding plates 702 are connected with the reset plate 602.

[0046] It should be noted that the guiding assembly provides a guiding function for the movement of the reset plate 602.

[0047] Please refer to Figure 6 and Figure 10 The fixing assembly in the figure comprises a plurality of fixing holes 801 formed in the side of the mounting plate 204 close to the detection probe 106, each fixing hole 801 is located on the two sides of the mounting hole 205, each fixing hole 801 is slidably connected with a T-shaped fixing rod 802, and the sidewall is sleeved with a third spring 803, the two ends of each third spring 803 are connected with the sidewall of the T-shaped fixing rod 802 and the mounting plate 204, and the end of each T-shaped fixing rod 802 away from the mounting plate 204 is rotatably connected with a rotating ball 804, and the two guide rails 201 are provided with a driving assembly for driving each T-shaped fixing rod 802 on the same side.

[0048] It should be noted that the fixing assembly is provided, and under the action of the driving assembly, the automatic fixing and automatic releasing of the sample placing plate 108 are realized, and the position stability of the sample placing plate 108 during subsequent uniform distribution of the sample is ensured.

[0049] Please refer to Figure 9 The driving assembly in the figure comprises a plurality of U-shaped plates 901 fixedly connected to the guide rail 201 close to the first L-shaped plate 301, the end of each U-shaped plate 901 away from the guide rail 201 is located above the mounting plate 204, and is fixedly connected with a driving strip-shaped plate 902, and the side of the driving strip-shaped plate 902 close to the detection port 104 is fixedly connected with an inclined plate 903.

[0050] It should be noted that the driving assembly is provided, which is used for pushing the T-shaped fixing rod 802, and thus the automatic fixing and automatic releasing of the sample placing plate 108 are realized.

[0051] Please refer to Figure 3 and Figure 4The moving assembly in the drawing comprises a lead screw 1001 rotatably connected between two inner walls of the detection shell 102, the lead screw 1001 is located between two guide rails 201, and a moving plate 1002 is threadedly connected to the lead screw 1001, one end of the moving plate 1002 is connected to a side of the sliding plate 202 away from the detection opening 104, a motor 1004 is fixedly connected to an inner wall of a side of the detection shell 102 away from the control shell 101, a first bevel gear 1005 is fixedly connected to an output end of the motor 1004, a second bevel gear 1003 is fixedly connected to a side wall of the lead screw 1001, and the second bevel gear 1003 and the first bevel gear 1005 are arranged in meshing relationship;

[0052] It should be noted that: through the arrangement of the moving assembly, the sample placing plate 108 can be conveniently moved out of or into the detection shell 102.

[0053] In the scheme: a single-cell neural cell imaging diagnostic instrument comprises the following steps:

[0054] When the single-cell neural cell imaging diagnosis of the detection sample is performed by using the single-cell analyzer, the cell suspension type detection sample is first placed in the sample pool 109 on the sample placing plate 108, and since the sample pool 109 has a plurality of sample pools, detection of a plurality of different samples can be simultaneously performed, after the sample is placed in the sample pool 109, the power control key 107 can be started, at this time, the motor 1004 is started to drive the lead screw 1001 to rotate, and then under the meshing transmission action of the lead screw 1001 and the moving plate 1002 and the guiding action of the two guide rails 201, the sliding plate 202 is driven to move, and then the mounting plate 204 is driven to move close to the detection opening 104, when the mounting plate 204 abuts against the baffle 105 on the detection opening 104, the baffle 105 will be moved under the pushing force, at this time, the mounting hole 205 on the mounting plate 204 will be moved out of the detection shell 102;

[0055] After the mounting hole 205 is moved out of the detection shell 102, the sample placing plate 108 can be inserted into the two insertion slots 206 of the mounting plate 204, after the sample placing plate 108 is inserted into the insertion slot 206, the power control key 107 can be pressed again, at this time, the motor 1004 is reversely rotated to drive the sliding plate 202 to shrink into the detection shell 102, and then the sample placing plate 108 on the mounting plate 204 is synchronously driven to shrink into the detection shell 102;

[0056] In the process of the installation plate 204 retracting into the detection shell 102, when the T-shaped fixing rod 802 on the installation plate 204 enters below the driving strip-shaped plate 902 under the guidance of the inclined plate 903, the T-shaped fixing rod 802 will be pushed to move close to the sample placement plate 108 under the extrusion of the driving strip-shaped plate 902, and then abut against the sample placement plate 108, so as to realize the fixing and limiting of the sample placement plate 108, and ensure the positional stability of the sample placement plate 108 when uniformly distributing the sample in the subsequent process;

[0057] When the uniformly distributed holes 304 of the side wall of the installation plate 204 abut against the tapered rod 303 at one end of the uniformly distributed rod 302 in the process of the continuous movement of the installation plate 204 into the detection shell 102, the installation plate 204 will be pushed to reciprocatingly move transversely under the interaction force and the elastic resetting and guiding of the resetting assembly and the guiding assembly, and in the process of the reciprocating transverse movement of the installation plate 204, the conversion plate 401 at one side of the installation plate 204 will reciprocatingly abut against the conversion rod 403, and then the installation plate 204 will be reciprocatingly moved longitudinally under the interaction force of the inclined surface 402 and the guiding and elastic resetting of the telescopic assembly, so that the installation plate 204 will be reciprocatingly moved transversely and longitudinally when retracting into the detection shell 102, and then the sample placement plate 108 will be reciprocatingly moved transversely and longitudinally, so that the sample in the sample pool 109 will be reciprocatingly moved transversely and longitudinally (the moving range of the transverse and longitudinal movement is small, and the sample will not overflow from the sample pool 109), so that the uniformity of the distribution of the sample in the sample pool 109 and the elimination of the bubbles in the sample are improved by the reciprocating transverse and longitudinal shaking, and then the low single-cell capture rate caused by the uneven distribution of the sample and the occlusion of the field of view by the bubbles are reduced, so that the precision of the single-cell neural cell imaging diagnosis is improved;

[0058] When the sample pool 109 of the sample placement plate 108 moves below the detection probe 106 in the process of the continuous movement of the sample placement plate 108, the movement of the sample placement plate 108 is stopped, at this time, the detection probe 106 uses optical, electrical, microfluidic and other technical means to realize the synchronous acquisition of multi-dimensional information at the single-cell scale, so as to provide accurate imaging basis for the pathological mechanism research and early diagnosis of neurological diseases (such as Alzheimer's disease and epilepsy), and the detection result can be presented in the form of image on the display screen 103 (the specific structure and working principle of the single-cell neural cell imaging diagnosis as prior art have been mastered by those skilled in the art, and will not be described in detail here).

[0059] It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting; it is not intended to exclude myriad other embodiments of the present application that other inventors can develop based on the same general inventive concepts embodied by the described embodiments. That is, although the present application is described in terms of particular embodiments and illustrative figures, it should be apparent that the scope of the present application is not limited to these specific embodiments.

[0060] While the embodiments of the application have been shown and described herein, it will be understood by those skilled in the art that many changes, modifications, substitutions and alterations to these embodiments can be made without departing from the principles and spirits of the application, and it is intended that the scope of the application be limited solely by the scope of the appended claims and the equivalents thereof.

Claims

1. A single-cell nerve cell imaging diagnostic instrument, comprising: A control housing (101) and a sample placement plate (108); one side of the control housing (101) is fixedly connected to a detection housing (102); the detection housing (102) is connected to a detection probe (106) via a bracket; a display screen (103) and a detection port (104) are provided on a side of the control housing (101) away from the detection housing (102); the detection port (104) is hinged with a baffle (105); the detection housing (102) is provided with a power control key (107); and the sample placement plate (108) is provided with a plurality of sample pools (109); It is characterized by further comprising: A mounting mechanism provided on the detection housing (102) for mounting the sample placement plate (108) and a distribution mechanism provided on the mounting mechanism for evenly distributing the sample in the sample pool (109); The mounting mechanism comprises two guide rails (201) fixedly connected to two inner walls of the detection housing (102) and arranged symmetrically with each other, the two guide rails (201) being slidably connected to a sliding plate (202), a mounting groove (203) being provided on one side of the sliding plate (202) close to the detection probe (106) and the detection port (104), the mounting groove (203) being slidably connected to a mounting plate (204), the mounting plate (204) being provided with a mounting hole (205), the mounting hole (205) being close to the detection port ( The mounting hole (205) is provided on one side thereof, and slots (206) are provided on two inner walls opposite to each other. The two slots (206) are matched with the sample placement plate (108). The mounting plate (204) is provided with a fixing component for fixing the sample placement plate (108), the sliding plate (202) is provided with a telescopic component for telescoping the sample placement plate (108) during the uniform distribution process, and the detection housing (102) is provided with a moving component for moving the sample placement plate (108).

2. The single-cell nerve cell imaging diagnostic instrument according to claim 1, characterized in that: The uniform distribution mechanism comprises a first L-shaped plate (301) fixedly connected to one side wall of the two guide rails (201); the first L-shaped plate (301) is arranged close to the detection port (104) and is fixedly connected to a uniform distribution rod (302) on a side close to the sliding plate (202); the uniform distribution rod (302) is fixedly connected to an end thereof away from the first L-shaped plate (301); a plurality of uniform distribution holes (304) arranged at equal intervals are opened on a side of the mounting plate (204) close to the conical rod (303); and each of the uniform distribution holes (304) is arranged at the same height as the conical rod (303).

3. The single-cell nerve cell imaging diagnostic instrument according to claim 2, characterized in that: A side of the sliding plate (202) close to the evenly distributed holes (304) is provided with an avoidance hole (305), and the tapered rod (303) is slidably connected to the avoidance hole (305).

4. The single-cell nerve cell imaging diagnostic instrument according to claim 3, characterized in that: The mounting plate (204) is provided with a transformation assembly for performing multi-directional position transformation on the sample placement plate (108), the transformation assembly comprising a plurality of transformation plates (401) fixedly connected to a side of the mounting plate (204) close to the sliding plate (202) and arranged at equal intervals, each transformation plate (401) having inclined surfaces (402) on opposite sides, a transformation rod (403) fixedly connected to a side of the mounting groove (203) close to the transformation plate (401), and the transformation rod (403) being located between two adjacent transformation plates (401).

5. The single-cell nerve cell imaging diagnostic instrument according to claim 4, characterized in that: The telescopic assembly comprises two second L-shaped plates (501) fixedly connected to the side of the sliding plate (202) away from the first L-shaped plate (301) and symmetrically arranged with each other; the sides of the two second L-shaped plates (501) close to the mounting plate (204) are connected to the telescopic blocks (502) through a reset assembly; two telescopic holes (503) are provided on the side of the sliding plate (202) close to the second L-shaped plate (501); a telescopic rod (504) is fixedly connected between two inner walls opposite to each other of the two telescopic holes (503); the two telescopic blocks (502) are slidably connected to the telescopic rod (504); the side walls of the two telescopic rods (504) are respectively sleeved with two first springs (505); and the two ends of the two first springs (505) are respectively connected to the telescopic blocks (502) and the inner walls of the telescopic holes (503).

6. The single-cell nerve cell imaging diagnostic instrument according to claim 5, characterized in that: The reset assembly comprises a reset tube (601) fixedly connected to a side of the second L-shaped plate (501) close to the telescopic block (502); the reset tube (601) is connected to the reset plate (602) via a guide assembly; a reset rod (603) is fixedly connected to a side of the reset plate (602) close to the telescopic block (502); an end of the reset rod (603) away from the reset plate (602) is connected to the telescopic block (502); a second spring (604) is fixedly connected to a side of the reset plate (602) away from the reset rod (603); and an end of the second spring (604) away from the reset plate (602) is connected to the bottom wall of the reset tube (601).

7. The single-cell nerve cell imaging diagnostic instrument according to claim 6, characterized in that: The guide assembly comprises two symmetrical guide holes (701) opened on the side wall of the reset tube (601), the two guide holes (701) are slidably connected to a guide plate (702), and opposite ends of the two guide plates (702) are connected to the reset plate (602).

8. The single-cell nerve cell imaging diagnostic instrument according to claim 7, characterized in that: The fixing assembly comprises a plurality of fixing holes (801) opened on a side of the mounting plate (204) close to the detection probe (106), each of the fixing holes (801) being located on both sides of the mounting hole (205), each of the fixing holes (801) being slidably connected to a T-shaped fixing rod (802), and a third spring (803) being sleeved on the side wall, and each of the two third springs (803) being connected to the side wall of the T-shaped fixing rod (802) and the mounting plate (204), respectively, and each of the T-shaped fixing rods (802) being rotatably connected to one end away from the mounting plate (204) with a rotating ball (804), and the two guide rails (201) being provided with a driving assembly for driving each of the T-shaped fixing rods (802) located on the same side.

9. The single-cell nerve cell imaging diagnostic instrument according to claim 8, characterized in that: The driving assembly comprises a plurality of U-shaped plates (901) fixedly connected to a side of the guide rail (201) close to the first L-shaped plate (301), one end of each U-shaped plate (901) away from the guide rail (201) is located above the mounting plate (204) and is fixedly connected to a driving strip plate (902), and a side of the driving strip plate (902) close to the detection port (104) is fixedly connected to an inclined plate (903).

10. The single-cell nerve cell imaging diagnostic instrument according to claim 9, characterized in that: The moving assembly comprises a screw rod (1001) rotatably connected between two opposite inner walls of the detection housing (102); the screw rod (1001) is located between two guide rails (201) and is threadedly connected to a moving plate (1002); one end of the moving plate (1002) is connected to a side of the sliding plate (202) away from the detection port (104); a motor (1004) is fixedly connected to an inner wall of a side of the detection housing (102) away from the control housing (101); an output end of the motor (1004) is fixedly connected to a first bevel gear (1005); a side wall of the screw rod (1001) is fixedly connected to a second bevel gear (1003); the second bevel gear (1003) and the first bevel gear (1005) are meshed with each other.

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