Sample analyzer

Abstract

The present invention is applicable to the field of in vitro diagnostic equipment, and discloses a sample analyzer, the sample analyzer comprises a sample distribution device, a sample detection device and a controller, the sample distribution device comprises a first sample dispensing assembly and a second sample dispensing assembly, the controller is configured to execute the following first detection process: controlling the first sample dispensing assembly to execute a sample distribution action, and obtaining a first detection result according to first detection data detected by the sample detection device and first calibration data; the controller is further configured to execute the following second detection process: controlling the second sample dispensing assembly to execute a sample distribution action, and obtaining a second detection result according to second detection data detected by the sample detection device and second calibration data; when the detection item executed by the first detection process and the detection item executed by the second detection process are the same detection item, the first calibration data and the second calibration data are the same calibration data. According to the invention, the detection efficiency is improved, and the calibration cost is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of in-vitro diagnostic equipment, in particular to a sample analyzer. BACKGROUND

[0002] A sample analyzer provided by the prior art adopts a single-needle pipetting device to dispense liquid, i.e. all the suction and dispensing actions of the same kind of liquid are performed by a single pipetting needle of a single pipetting device, i.e. the dispensing of the same kind of liquid in all detection items in the sample analyzer is performed by the same pipetting needle, for example, the sample dispensing actions of all detection items in the sample analyzer are performed by the same sample needle, and the reagent dispensing actions of all detection items are performed by the same reagent needle. Since the pipetting speed of the single-needle pipetting device has an upper limit, the sample detection speed of the whole machine is also limited, which is not conducive to the improvement of the detection speed of the sample analyzer. In order to improve the detection speed of the sample analyzer, the related technology proposes a scheme of using a double-needle pipetting device or a three-needle pipetting device or even more needle pipetting devices to dispense samples or reagents, i.e. using two sample needles or three sample needles or more sample needles to perform sample dispensing actions respectively, or using two reagent needles or three reagent needles or more reagent needles to perform reagent dispensing actions respectively. When using a double-needle pipetting device or a three-needle pipetting device or even more needle pipetting devices to dispense samples or reagents, there will be differences in dispensing accuracy when different pipetting needle channels dispense the same kind of liquid, which may cause the precision of the whole machine to not meet the performance requirements of clinical analysis.

[0003] To solve the problem of precision decline caused by pipetting with different pipetting needles, the solutions proposed by the related art mainly include the following two schemes: (1) Scheme one, each pipetting needle is used to perform pipetting action in different detection items, that is, different pipetting needles are responsible for pipetting action of different specified detection items respectively, and do not interfere with each other. In this scheme, each pipetting needle performs clinical calibration of the corresponding specified item independently; scheme two, each detection item is calibrated for each pipetting needle. Thus, several pipetting needles require several sets of calibration standards and corresponding reagents. However, both of the two schemes have deficiencies in specific application, which are embodied in: (1) In scheme one, since each pipetting needle is used to perform pipetting action in different specified detection items, when there are many samples to perform a certain detection item in a time period, a phenomenon of long queue of many samples waiting for pipetting action under the pipetting needle corresponding to the detection item will occur, while other pipetting needles are in idle state, which causes great waste of resources and leads to speed reduction in a large number of clinical detection scenarios, thereby greatly reducing the actual detection efficiency of the sample analyzer, which is contrary to the speed-up goal of using multiple needles for pipetting. (2) In scheme two, since each detection item needs to be calibrated for each pipetting needle respectively, on the one hand, the use amount of calibration standards and corresponding reagents is increased, thereby increasing the calibration cost; on the other hand, the calibration efficiency is reduced; and on the other hand, since the performance transmission chain of the clinical results and the pipetting accuracy is long, or the accuracy difference of different pipetting needles cannot be reflected by single detection clinical data, the use of clinical item calibration may cause more uncontrollable calibration deviation. SUMMARY

[0004] The first object of the present application is to provide a sample analyzer which aims to solve the technical problem of being unable to balance detection efficiency and calibration cost and calibration efficiency when a multi-needle pipetting device is used to perform pipetting action of the same liquid in the related art.

[0005] To achieve the above object, the present application provides a solution: a sample analyzer, comprising:

[0006] A sample dispensing device, the sample dispensing device comprising a first sample dispensing assembly and a second sample dispensing assembly, the first sample dispensing assembly and the second sample dispensing assembly being used to perform the following sample dispensing action: sucking sample from a sample container and dispensing at least part of the sucked sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, the first sample needle and the second sample needle being two sample needles capable of independently performing the sample dispensing action;

[0007] A reagent dispensing device for performing a reagent dispensing action of sucking a reagent from a reagent container and dispensing at least part of the sucked reagent into a reaction container;

[0008] A sample detecting device for detecting a sample to be tested made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the reagent dispensing device;

[0009] A controller configured to perform a first detecting procedure of controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detecting device to detect a sample to be tested made of at least a sample dispensed by the first sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining first detecting data according to detecting information fed back by the sample detecting device, and obtaining a first detecting result according to the first detecting data and first calibration data;

[0010] The controller is further configured to perform a second detecting procedure of controlling the second sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detecting device to detect a sample to be tested made of at least a sample dispensed by the second sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining second detecting data according to detecting information fed back by the sample detecting device, and obtaining a second detecting result according to the second detecting data and second calibration data;

[0011] When the detecting item performed by the first detecting procedure and the detecting item performed by the second detecting procedure are the same detecting item, the first calibration data and the second calibration data are the same calibration data.

[0012] As an implementation form, the deviation of the sample dispensing precision of the first sample dispensing assembly and the sample dispensing precision of the second sample dispensing assembly is less than or equal to a first preset value, the first preset value is greater than or equal to zero and less than or equal to 5%.

[0013] As an implementation form, the first preset value is less than or equal to 2%.

[0014] As an implementation form, the sample analyzer further comprises a dispensed volume detection device, and the controller is further configured to perform a sample addition calibration process as follows: controlling the first sample dispensing assembly to aspirate a sample addition calibration sample and dispense it into a reaction vessel, controlling the dispensed volume detection device to detect a first calibration sample dispensed volume dispensed by the first sample dispensing assembly into the reaction vessel; controlling the second sample dispensing assembly to aspirate the sample addition calibration sample and dispense it into a reaction vessel, controlling the dispensed volume detection device to detect a second calibration sample dispensed volume dispensed by the second sample dispensing assembly into the reaction vessel; and correcting the sample dispensing volume of the first sample dispensing assembly in the sample dispensing action and / or the sample dispensing volume of the second sample dispensing assembly in the sample dispensing action according to the first calibration sample dispensed volume and the second calibration sample dispensed volume, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value.

[0015] As an implementation form, the correction of the sample dispensing volume of the first sample dispensing assembly in the sample dispensing action and / or the sample dispensing volume of the second sample dispensing assembly in the sample dispensing action according to the first calibration sample dispensed volume and the second calibration sample dispensed volume comprises:

[0016] calculating a first deviation value of the second calibration sample dispensed volume relative to the first calibration sample dispensed volume, and correcting the sample dispensing volume of the second sample dispensing assembly in the sample dispensing action according to the first deviation value; or

[0017] calculating a second deviation value of the first calibration sample dispensed volume relative to the second calibration sample dispensed volume, and correcting the sample dispensing volume of the first sample dispensing assembly in the sample dispensing action according to the second deviation value.

[0018] As an implementation form, the correction of the sample dispensing volume of the first sample dispensing assembly in the sample dispensing action and / or the sample dispensing volume of the second sample dispensing assembly in the sample dispensing action according to the first calibration sample dispensed volume and the second calibration sample dispensed volume comprises: calculating a third deviation value of the first calibration sample dispensed volume relative to a reference volume, calculating a fourth deviation value of the second calibration sample dispensed volume relative to the reference volume, correcting the sample dispensing volume of the first sample dispensing assembly in the sample dispensing action according to the third deviation value, and correcting the sample dispensing volume of the second sample dispensing assembly in the sample dispensing action according to the fourth deviation value;

[0019] The reference amount is a target dispensing amount of the sample actually required to be dispensed by the sample dispensing device to the reaction container in the sample dispensing action, or the reference amount has a preset difference with the target dispensing amount of the sample actually required to be dispensed by the sample dispensing device to the reaction container in the sample dispensing action.

[0020] As an implementation, the correction of the sample dispensing amount of the first sample dispensing assembly in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly in the sample dispensing action according to the first calibration dispensing amount and the second calibration dispensing amount comprises:

[0021] A first deviation value of the second calibration dispensing amount relative to the first calibration dispensing amount is calculated, a first correction parameter is obtained according to the first deviation value, a corrected sample dispensing amount of the first sample dispensing assembly is obtained based on a target dispensing amount of the sample actually required to be dispensed by the sample dispensing device to the reaction container in the sample dispensing action and the first correction parameter, and the sample dispensing amount of the second sample dispensing assembly remains unchanged; or,

[0022] A second deviation value of the first calibration dispensing amount relative to the second calibration dispensing amount is calculated, a second correction parameter is obtained according to the second deviation value, a corrected sample dispensing amount of the second sample dispensing assembly is obtained based on the target dispensing amount of the sample actually required to be dispensed by the sample dispensing device to the reaction container in the sample dispensing action and the second correction parameter, and the sample dispensing amount of the first sample dispensing assembly remains unchanged; or,

[0023] A third deviation value of the first calibration dispensing amount relative to a reference amount is calculated, a third correction parameter is obtained according to the third deviation value, a corrected sample dispensing amount of the first sample dispensing assembly is obtained based on the target dispensing amount of the sample actually required to be dispensed by the sample dispensing device to the reaction container in the sample dispensing action and the third correction parameter; a fourth deviation value of the second calibration dispensing amount relative to the reference amount is calculated, a fourth correction parameter is obtained according to the fourth deviation value, and a corrected sample dispensing amount of the second sample dispensing assembly is obtained based on the target dispensing amount and the fourth correction parameter; wherein the reference amount is the target dispensing amount, or the reference amount has a preset difference with the target dispensing amount.

[0024] As an implementation, the dispensing amount detection device is a weighing device, and the control of the dispensing amount detection device to detect the first calibrant dispensing amount dispensed by the first sample dispensing assembly into the reaction container comprises: controlling the weighing device to weigh the weight of the sample calibrant dispensed by the first sample dispensing assembly into the reaction container, and obtaining the first calibrant dispensing amount dispensed by the first sample dispensing assembly into the reaction container according to the weight information fed back by the weighing device.

[0025] The control of the dispensing amount detection device to detect the second calibrant dispensing amount dispensed by the second sample dispensing assembly into the reaction container comprises: controlling the weighing device to weigh the weight of the sample calibrant dispensed by the second sample dispensing assembly into the reaction container, and obtaining the second calibrant dispensing amount dispensed by the second sample dispensing assembly into the reaction container according to the weight information fed back by the weighing device.

[0026] As an implementation, the dispensing amount detection device is a first optical detection device, and the sample calibrant is a pigment solution; the control of the first sample dispensing assembly to suck the sample calibrant and dispense it into the reaction container, and the control of the dispensing amount detection device to detect the first calibrant dispensing amount dispensed by the first sample dispensing assembly into the reaction container comprises: controlling the first sample dispensing assembly to suck the pigment solution and dispense it into the reaction container, and controlling the first optical detection device to detect the absorbance of the pigment solution dispensed by the first sample dispensing assembly into the reaction container, so as to obtain the first calibrant dispensing amount dispensed by the first sample dispensing assembly into the reaction container; and the control of the second sample dispensing assembly to suck the sample calibrant and dispense it into the reaction container, and the control of the dispensing amount detection device to detect the second calibrant dispensing amount dispensed by the second sample dispensing assembly into the reaction container comprises: controlling the second sample dispensing assembly to suck the pigment solution and dispense it into the reaction container, and controlling the first optical detection device to detect the absorbance of the pigment solution dispensed by the second sample dispensing assembly into the reaction container, so as to obtain the second calibrant dispensing amount dispensed by the second sample dispensing assembly into the reaction container; or,

[0027] The distribution amount detection device is a first optical detection device, and the sample calibration solution is a pigment solution; the control of the first sample dispensing assembly to suck the sample calibration solution and distribute it in the reaction container, and the control of the distribution amount detection device to detect the first calibration solution distribution amount distributed in the reaction container by the first sample dispensing assembly, comprises: control the first sample dispensing assembly to suck the pigment solution and distribute it in the reaction container, control the reagent dispensing device to suck the diluent and distribute it in the reaction container, control the first optical detection device to detect the absorbance of the first mixed solution formed by at least the pigment solution distributed in the reaction container by the first sample dispensing assembly and the diluent distributed in the reaction container by the reagent dispensing device, to obtain the first calibration solution distribution amount distributed in the reaction container by the first sample dispensing assembly; the control of the second sample dispensing assembly to suck the sample calibration solution and distribute it in the reaction container, and the control of the distribution amount detection device to detect the second calibration solution distribution amount distributed in the reaction container by the second sample dispensing assembly, comprises: control the second sample dispensing assembly to suck the pigment solution and distribute it in the reaction container, control the reagent dispensing device to suck the diluent and distribute it in the reaction container, control the first optical detection device to detect the absorbance of the second mixed solution formed by at least the pigment solution distributed in the reaction container by the second sample dispensing assembly and the diluent distributed in the reaction container by the reagent dispensing device, to obtain the second calibration solution distribution amount distributed in the reaction container by the second sample dispensing assembly; or,

[0028] The distribution amount detection device is a first optical detection device, and the sample calibration liquid is a diluent; the control of the first sample dispensing assembly to suck the sample calibration liquid and distribute it in the reaction container and the control of the distribution amount detection device to detect the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly include: control of the first sample dispensing assembly to suck the diluent and distribute it in the reaction container, control of the reagent distribution device to suck the pigment solution and distribute it in the reaction container, and control of the first optical detection device to detect the absorbance of a third mixed liquid formed by mixing at least the diluent distributed in the reaction container by the first sample dispensing assembly and the pigment solution distributed in the reaction container by the reagent distribution device, to obtain the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly; the control of the second sample dispensing assembly to suck the sample calibration liquid and distribute it in the reaction container and the control of the distribution amount detection device to detect the second calibration liquid distribution amount distributed in the reaction container by the second sample dispensing assembly include: control of the second sample dispensing assembly to suck the diluent and distribute it in the reaction container, control of the reagent distribution device to suck the pigment solution and distribute it in the reaction container, and control of the first optical detection device to detect the absorbance of a fourth mixed liquid formed by mixing at least the diluent distributed in the reaction container by the second sample dispensing assembly and the pigment solution distributed in the reaction container by the reagent distribution device, to obtain the second calibration liquid distribution amount distributed in the reaction container by the second sample dispensing assembly.

[0029] As an implementation manner, the distribution amount detection device is a second optical detection device, and the sample calibration liquid is a first marker reagent with a luminescent marker;

[0030] The sample analyzer further comprises a substrate distribution device for distributing a luminescent substrate reagent into the reaction container;

[0031] The control of the first sample dispensing assembly to suck the sample calibration liquid and distribute it in the reaction container and the control of the distribution amount detection device to detect the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly include: control of the first sample dispensing assembly to suck the first marker reagent and distribute it in the reaction container, control of the substrate distribution device to distribute the luminescent substrate reagent into the reaction container, and control of the second optical detection device to detect the luminescent intensity of a first reaction liquid made of at least the first marker reagent distributed in the reaction container by the first sample dispensing assembly and the luminescent substrate reagent distributed in the reaction container by the substrate distribution device, to obtain the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly;

[0032] The control of the second sample dispensing assembly to suck and dispense the calibration sample into the reaction container, and the control of the dispensing amount detection device to detect the second calibration sample dispensing amount dispensed by the second sample dispensing assembly into the reaction container, include: controlling the second sample dispensing assembly to suck and dispense the first marker reagent into the reaction container, controlling the substrate dispensing device to dispense the luminescent substrate reagent into the reaction container, and controlling the second optical detection device to detect the luminescent intensity of the second reaction liquid made of the first marker reagent dispensed by the second sample dispensing assembly into the reaction container and the luminescent substrate reagent dispensed by the substrate dispensing device into the reaction container, to obtain the second calibration sample dispensing amount dispensed by the second sample dispensing assembly into the reaction container.

[0033] As an embodiment, the reagent dispensing device performs the reagent dispensing action, including: sucking and dispensing the magnetic bead reagent with magnetic beads from a first reagent container into a reaction container, and sucking and dispensing the second marker reagent with a luminescent marker from a second reagent container into the reaction container.

[0034] The reaction device is used to carry the reaction container to incubate a liquid containing at least a sample, the magnetic bead reagent, and the second marker reagent, to make a third reaction liquid.

[0035] The sample analyzer further includes a magnetic separation device, which is used to perform a magnetic separation and cleaning operation on the third reaction liquid to make a fourth reaction liquid.

[0036] The substrate dispensing device is further used to dispense a luminescent substrate reagent into the fourth reaction liquid, so that the fourth reaction liquid and the luminescent substrate reagent make the to-be-tested liquid.

[0037] The sample detection device is used to detect the luminescent intensity of the to-be-tested liquid.

[0038] Among them, the sample adding calibration process and the first detection process and the second detection process are different in at least one of the following: the components of the first marker reagent and the components of the second marker reagent are different, the concentration of the first marker reagent and the concentration of the second marker reagent are different, the dispensing amount of the first marker reagent and the dispensing amount of the second marker reagent are different, the dispensing amount of the luminescent substrate reagent is different, the incubation time is different, and the incubation temperature is different.

[0039] As an implementation form, the sample analyzer pre-stores a first preset condition, and the first preset condition at least includes one of the following: a first preset time length is reached since last execution of the sample adding calibration process; information that the first sample dispensing assembly and / or the second sample dispensing assembly completes fault maintenance is obtained; information that the first sample dispensing assembly and / or the second sample dispensing assembly completes loading is obtained; a first preset time point of a first preset maintenance cycle is reached;

[0040] The controller is further configured to execute the sample adding calibration process when the first preset condition is met.

[0041] As an implementation form, the first sample dispensing assembly and the second sample dispensing assembly share at least part of components.

[0042] As an implementation form, the first sample dispensing assembly further includes a first dispensing power component, and the first dispensing power component is used to provide driving force for the first sample needle to perform a dispensing action.

[0043] The second sample dispensing assembly further includes a second dispensing power component, and the second dispensing power component is used to provide driving force for the second sample needle to perform a dispensing action.

[0044] The first dispensing power component and the second dispensing power component are the same dispensing power component.

[0045] As an implementation form, the first sample needle is configured with a first identification code, and the first identification code is associated with sample adding correction parameters of the first sample needle; the sample analyzer further includes a first information acquisition component, and the first information acquisition component is used to identify the first identification code; the controller is further configured to obtain the sample adding correction parameters of the first sample needle according to information fed back by the first information acquisition component identifying the first identification code; and at least according to the sample adding correction parameters of the first sample needle, the sample dispensing amount of the first sample dispensing assembly in performing the sample dispensing action is corrected, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value; and / or,

[0046] The second sample needle is configured with a second identification code, and the second identification code is associated with sample loading correction parameters of the second sample needle; the sample analyzer further comprises a first information acquisition component configured to identify the second identification code; and the controller is further configured to: acquire the sample loading correction parameters of the second sample needle according to information fed back by the first information acquisition component in identifying the second identification code; and correct sample dispensing amount of the second sample dispensing assembly in performing the sample dispensing action according to at least the sample loading correction parameters of the second sample needle, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value.

[0047] As an implementation form, the controller is further configured to: before controlling the first sample needle to perform the sample dispensing action for the first time on the sample analyzer, acquire sample loading correction parameters of the first sample needle according to information fed back by the first information acquisition component in identifying the first identification code; and / or,

[0048] The controller is further configured to: before controlling the second sample needle to perform the sample dispensing action for the first time on the sample analyzer, acquire sample loading correction parameters of the second sample needle according to information fed back by the first information acquisition component in identifying the second identification code.

[0049] As an implementation form, the first sample dispensing assembly further comprises a first suction power component configured to provide driving force for the first sample needle to perform a suction action; the first suction power component is configured with a third identification code, and the third identification code is associated with sample loading correction parameters of the first suction power component; the sample analyzer further comprises a first information acquisition component configured to identify the third identification code; and the controller is further configured to: acquire the sample loading correction parameters of the first suction power component according to information fed back by the first information acquisition component in identifying the third identification code; correct sample dispensing amount of the first sample dispensing assembly in performing the sample dispensing action according to the sample loading correction parameters of the first suction power component, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value; and / or,

[0050] The second sample dispensing assembly further comprises a second suction and injection power component configured to provide driving force for the suction and injection action of the second sample needle; the second suction and injection power component is provided with a fourth identification code, and the fourth identification code is associated with the sample addition correction parameter of the second suction and injection power component; the sample analyzer further comprises a first information acquisition component configured to identify the fourth identification code; and the controller is further configured to: acquire the sample addition correction parameter of the second suction and injection power component according to the information fed back by the first information acquisition component identifying the fourth identification code; and correct the sample dispensing amount of the second sample dispensing assembly in the sample dispensing action according to the sample addition correction parameter of the second suction and injection power component, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value.

[0051] As an implementation form, the controller is further configured to: before controlling the first suction and injection power component to perform the sample dispensing action on the sample analyzer for the first time, acquire the sample addition correction parameter of the first suction and injection power component according to the information fed back by the first information acquisition component identifying the third identification code; and / or,

[0052] The controller is further configured to: before controlling the second suction and injection power component to perform the sample dispensing action on the sample analyzer for the first time, acquire the sample addition correction parameter of the second suction and injection power component according to the information fed back by the first information acquisition component identifying the fourth identification code.

[0053] As an implementation form, the sample analyzer further comprises a reaction device configured to carry a reaction container to incubate a sample and a reagent in the reaction container; the controller is further configured to: control the same reagent dispensing device to perform the reagent dispensing action in the first detection process and the reagent dispensing action in the second detection process respectively; control the same reaction device to incubate the sample and the reagent in the first detection process and the sample and the reagent in the second detection process respectively; and control the same sample detection device to detect the to-be-detected liquid in the first detection process and the to-be-detected liquid in the second detection process respectively.

[0054] As an implementation form, the reagent dispensing device performing the reagent dispensing action comprises: sucking a magnetic bead reagent from a first reagent container and dispensing it into a reaction container; and sucking a second marker reagent from a second reagent container and dispensing it into the reaction container.

[0055] The reaction device is configured to carry a reaction container to incubate a liquid containing at least a sample, the magnetic bead reagent and the second marker reagent to prepare a third reaction liquid.

[0056] The sample analyzer further comprises a magnetic separation device and a substrate dispensing device, the magnetic separation device being configured to perform a magnetic separation and washing operation on the third reaction solution to produce a fourth reaction solution;

[0057] The substrate dispensing device is configured to perform a substrate dispensing action of: sucking a luminescent substrate reagent from a substrate reagent container, and dispensing at least part of the sucked luminescent substrate reagent into a reaction container, so as to produce the to-be-tested solution from the fourth reaction solution and the luminescent substrate reagent;

[0058] The sample detection device is configured to detect a luminescent intensity of the to-be-tested solution;

[0059] The controller is further configured to: control the same magnetic separation device to perform the magnetic separation and washing operation in the first detection process and the magnetic separation and washing operation in the second detection process, respectively; and control the same substrate dispensing device to perform the substrate dispensing action in the first detection process and the substrate dispensing action in the second detection process, respectively.

[0060] As an implementation form, the controller is further configured to perform a project calibration process of a first detection item as follows: control the first sample dispensing assembly to suck a project calibration sample from a second calibration sample container and dispense the project calibration sample into a reaction container, control the reagent dispensing device to suck a reagent from a reagent container and dispense the reagent into the reaction container, control the sample detection device to detect a calibration solution at least produced from the project calibration sample and the reagent in the reaction container, and obtain first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device.

[0061] The controller is further configured to perform a second detection process of the first detection item as follows: control the second sample dispensing assembly to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the to-be-tested solution at least produced from the sample dispensed by the second sample dispensing assembly and the reagent dispensed by the reagent dispensing device, obtain second detection data according to detection information fed back by the sample detection device, and obtain a second detection result according to the second detection data and the first calibration data corresponding to the first detection item.

[0062] A second object of the present application is to provide a sample analyzer, which comprises:

[0063] A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform a sample dispensing action of: drawing a sample from a sample container, and dispensing at least part of the drawn sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, the first sample needle and the second sample needle are two sample needles capable of performing the sample dispensing action independently of each other.

[0064] A reagent dispensing device, configured to perform a reagent dispensing action of: drawing a reagent from a reagent container, and dispensing at least part of the drawn reagent into a reaction container.

[0065] A sample detection device, configured to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the reagent dispensing device.

[0066] A controller, configured to perform a project calibration process of a first detection item, the controller is configured to: control the first sample dispensing assembly to draw a project calibration sample from a second calibration sample container and dispense the project calibration sample into a reaction container, control the reagent dispensing device to draw a reagent from a reagent container and dispense the reagent into the reaction container; control the sample detection device to detect a calibration liquid made of at least the project calibration sample and the reagent in the reaction container, and obtain first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device.

[0067] The controller is further configured to perform a second detection process of the first detection item, the controller is configured to: control the second sample dispensing assembly to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the to-be-tested liquid made of at least a sample dispensed by the second sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtain second detection data according to detection information fed back by the sample detection device, and obtain a second detection result according to the second detection data and the first calibration data corresponding to the first detection item.

[0068] As an implementation form, the sample analyzer further comprises a dispensing amount detection device, and the controller is further configured to perform a sample addition calibration process as follows: controlling the first sample dispensing assembly to aspirate a sample addition calibration sample and dispense it into a reaction container, controlling the dispensing amount detection device to detect a first calibration sample dispensing amount dispensed by the first sample dispensing assembly into the reaction container; controlling the second sample dispensing assembly to aspirate the sample addition calibration sample and dispense it into a reaction container, controlling the dispensing amount detection device to detect a second calibration sample dispensing amount dispensed by the second sample dispensing assembly into the reaction container; and correcting the sample dispensing amount of the first sample dispensing assembly in performing the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly in performing the sample dispensing action according to the first calibration sample dispensing amount and the second calibration sample dispensing amount, so that the deviation of the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value.

[0069] As an implementation form, the first sample dispensing assembly further comprises a first aspirating power component for providing driving force for the aspirating action of the first sample needle;

[0070] The second sample dispensing assembly further comprises a second aspirating power component for providing driving force for the aspirating action of the second sample needle;

[0071] The first aspirating power component and the second aspirating power component are the same aspirating power component.

[0072] As an implementation form, the first sample needle is configured with a first identification code, and the first identification code is associated with sample addition correction parameters of the first sample needle; the sample analyzer further comprises a first information acquisition component for identifying the first identification code; and the controller is further configured to: acquire the sample addition correction parameters of the first sample needle according to the information fed back by the first information acquisition component identifying the first identification code; and correct the sample dispensing amount of the first sample dispensing assembly in performing the sample dispensing action according to at least the sample addition correction parameters of the first sample needle, so that the deviation of the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value; and / or,

[0073] The second sample needle is configured with a second identification code, and the second identification code is associated with a sample adding correction parameter of the second sample needle; the sample analyzer further comprises a first information acquisition component, which is used to identify the second identification code; the controller is further configured to: acquire the sample adding correction parameter of the second sample needle according to the information fed back by the first information acquisition component identifying the second identification code; and correct the sample dispensing amount of the second sample dispensing assembly in performing the sample dispensing action according to at least the sample adding correction parameter of the second sample needle, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly and the sample dispensing accuracy of the second sample dispensing assembly is less than or equal to a first preset value.

[0074] A third object of the present application is to provide a sample analyzer comprising:

[0075] A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, the first sample dispensing assembly and the second sample dispensing assembly are respectively used to perform a sample dispensing action of: sucking a sample from a sample container and dispensing at least part of the sucked sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, the first sample needle and the second sample needle are two sample needles capable of independently performing the sample dispensing action;

[0076] A reagent dispensing device, used to perform a reagent dispensing action of: sucking a reagent from a reagent container and dispensing at least part of the sucked reagent into a reaction container;

[0077] A sample detection device, used to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the reagent dispensing device;

[0078] A controller, configured to perform a first detection process of: controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-tested liquid made of at least a sample dispensed by the first sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining first detection data according to detection information fed back by the sample detection device, and obtaining a first detection result according to the first detection data and first calibration data;

[0079] The controller is further configured to perform a second detection procedure as follows: controlling the second sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-detected liquid made of at least a sample dispensed by the second sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining second detection data according to detection information fed back by the sample detection device, and obtaining a second detection result according to the second detection data and second calibration data.

[0080] The sample analyzer is configured with a first working mode and a second working mode.

[0081] In the first working mode, the controller is configured to set the first calibration data and the second calibration data to use a same calibration data when detection items performed by the first detection procedure and the second detection procedure are the same detection items.

[0082] In the second working mode, the controller is configured to set the first calibration data and the second calibration data to use two different calibration data respectively when detection items performed by the first detection procedure and the second detection procedure are the same detection items.

[0083] As an implementation manner, the controller is configured to perform a project calibration procedure of a first detection item as follows: controlling the first sample dispensing assembly to suck a project calibration sample from a second calibration sample container and dispense the project calibration sample into a reaction container, controlling the reagent dispensing device to suck a reagent from a reagent container and dispense the reagent into the reaction container, and controlling the sample detection device to detect a calibration liquid made of at least the project calibration sample and the reagent in the reaction container, and obtaining first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device.

[0084] In the first working mode, the controller is configured to perform a second detection procedure of the first detection item as follows: controlling the second sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect the to-be-detected liquid made of at least a sample dispensed by the second sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining second detection data according to detection information fed back by the sample detection device, and obtaining a second detection result according to the second detection data and the first calibration data corresponding to the first detection item.

[0085] A fourth object of the present application is to provide a sample analyzer comprising:

[0086] A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform a sample dispensing action of: drawing a sample from a sample container, and dispensing at least part of the drawn sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, the first sample needle and the second sample needle are two sample needles capable of performing the sample dispensing action independently of each other.

[0087] A reagent dispensing device, configured to perform a reagent dispensing action of: drawing a reagent from a reagent container, and dispensing at least part of the drawn reagent into a reaction container.

[0088] A sample detection device, configured to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the reagent dispensing device.

[0089] A controller, configured to perform a first detection process of: controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-tested liquid made of at least a sample dispensed by the first sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining first detection data according to detection information fed back by the sample detection device, and obtaining a first detection result according to the first detection data and first calibration data.

[0090] The controller is further configured to perform a second detection process of: controlling the second sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-tested liquid made of at least a sample dispensed by the second sample dispensing assembly and a reagent dispensed by the reagent dispensing device, obtaining second detection data according to detection information fed back by the sample detection device, and obtaining a second detection result according to the second detection data and second calibration data.

[0091] The controller is further configured to: when a detection item performed by the first detection process and a detection item performed by the second detection process are both a first detection item, set the first calibration data and the second calibration data to adopt a same calibration data; when the detection item performed by the first detection process and the detection item performed by the second detection process are both a second detection item, set the first calibration data and the second calibration data to respectively adopt two different calibration data; and the first detection item and the second detection item are two different detection items.

[0092] As an implementation, the controller is further configured to perform a project calibration procedure of the first detection item, including: controlling the first sample dispensing assembly to aspirate a project calibration reagent from a second calibration reagent container and dispense the project calibration reagent into a reaction container, and controlling the reagent dispensing device to aspirate a reagent from a reagent container and dispense the reagent into the reaction container; controlling the sample detection device to detect a calibration solution made at least from the project calibration reagent and the reagent in the reaction container, and obtaining first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device.

[0093] The controller is configured to perform a second detection procedure of the first detection item, including: controlling the second sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, and controlling the sample detection device to detect the to-be-detected solution made at least from the sample dispensed by the second sample dispensing assembly and the reagent dispensed by the reagent dispensing device, obtaining second detection data according to detection information fed back by the sample detection device, and obtaining a second detection result according to the second detection data and the first calibration data corresponding to the first detection item.

[0094] A fifth object of the present application is to provide a sample analyzer, which comprises:

[0095] A sample dispensing device, configured to perform a sample dispensing action of aspirating a sample from a sample container and dispensing at least part of the aspirated sample into a reaction container;

[0096] A reagent dispensing device, comprising a first reagent dispensing assembly and a second reagent dispensing assembly, and configured to perform a reagent dispensing action of aspirating a reagent from a reagent container and dispensing at least part of the aspirated reagent into a reaction container; wherein the first reagent dispensing assembly comprises a first reagent needle, and the second reagent dispensing assembly comprises a second reagent needle, and the first reagent needle and the second reagent needle are two reagent needles capable of performing the reagent dispensing action independently of each other;

[0097] A sample detection device, configured to detect a to-be-detected solution made at least from a sample dispensed by the sample dispensing device and a reagent dispensed by the reagent dispensing device;

[0098] a controller configured to perform a third detection procedure of controlling the sample dispensing device to perform the sample dispensing action, controlling the first reagent dispensing assembly to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the first reagent dispensing assembly, obtaining third detection data according to detection information fed back by the sample detection device, and obtaining a third detection result according to the third detection data and third calibration data;

[0099] the controller is further configured to perform a fourth detection procedure of controlling the sample dispensing device to perform the sample dispensing action, controlling the second reagent dispensing assembly to perform the reagent dispensing action, controlling the sample detection device to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the second reagent dispensing assembly, obtaining fourth detection data according to detection information fed back by the sample detection device, and obtaining a fourth detection result according to the fourth detection data and fourth calibration data;

[0100] When the detection item performed by the third detection procedure is the same as the detection item performed by the fourth detection procedure, the third calibration data and the fourth calibration data are the same calibration data.

[0101] As an implementation form, the controller is further configured to perform an item calibration procedure of the first detection item, which includes controlling the sample dispensing device to suck an item calibration sample from a second calibration sample container and dispense the item calibration sample into a reaction container, controlling the first reagent dispensing assembly to suck a reagent from a reagent container and dispense the reagent into the reaction container, and controlling the sample detection device to detect a calibration liquid made of at least the item calibration sample and the reagent in the reaction container, and obtaining third calibration data corresponding to the first detection item according to detection information fed back by the sample detection device.

[0102] The controller is further configured to perform a fourth detection procedure of the first detection item, which includes controlling the sample dispensing device to perform the sample dispensing action, controlling the second reagent dispensing assembly to perform the reagent dispensing action, controlling the sample detection device to detect the to-be-tested liquid made of at least a sample dispensed by the sample dispensing device and a reagent dispensed by the second reagent dispensing assembly, obtaining fourth detection data according to detection information fed back by the sample detection device, and obtaining a fourth detection result according to the fourth detection data and the third calibration data corresponding to the first detection item.

[0103] A sixth object of the present application is to provide a sample analyzer, which comprises:

[0104] A pipetting device, comprising a first pipetting assembly and a second pipetting assembly, wherein the first pipetting assembly and the second pipetting assembly are respectively configured to perform the following liquid dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; and aspirating a reagent from a reagent container and dispensing at least a portion of the aspirated reagent into the reaction container; the first pipetting assembly comprising a first pipetting needle, and the second pipetting assembly comprising a second pipetting needle, wherein the first pipetting needle and the second pipetting needle are two pipetting needles capable of independently performing the liquid dispensing actions;

[0105] a sample detection device for detecting a test liquid prepared by at least the sample dispensed by the pipetting device and the reagent;

[0106] a controller configured to execute the following fifth detection process: controlling the first pipetting assembly to perform the liquid dispensing action, controlling the sample detection device to detect the test liquid prepared by at least the sample and reagent dispensed by the first pipetting assembly, obtaining fifth detection data based on detection information fed back by the sample detection device, and obtaining a fifth detection result based on the fifth detection data and fifth calibration data;

[0107] The controller is further configured to execute the following sixth detection process: controlling the second pipetting assembly to perform the liquid dispensing action, controlling the sample detection device to detect the test liquid prepared by at least the sample and reagent dispensed by the second pipetting assembly, obtaining sixth detection data based on detection information fed back by the sample detection device, and obtaining a sixth detection result based on the sixth detection data and sixth calibration data;

[0108] When the inspection item executed in the fifth inspection process is the same as the inspection item executed in the sixth inspection process, the fifth calibration data and the sixth calibration data are the same calibration data.

[0109] As an embodiment, the controller is further configured to: the controller is further configured to execute the following project calibration process for the first test item: control the first pipetting component to draw the project calibrator from the second calibrator container and dispense it into the reaction container, control the first pipetting component to draw the reagent from the reagent container and dispense it into the reaction container; control the sample detection device to detect the calibration liquid prepared from at least the project calibrator and the reagent in the reaction container, and obtain fifth calibration data corresponding to the first test item based on the detection information fed back by the sample detection device;

[0110] The controller is configured to perform a sixth detection process of the first detection item, control the second liquid transfer assembly to perform the liquid dispensing action, control the sample detection device to detect the sample to be tested made of the sample dispensed by the second liquid transfer assembly and the reagent, obtain sixth detection data according to detection information fed back by the sample detection device, and obtain a sixth detection result according to the sixth detection data and the fifth calibration data corresponding to the first detection item.

[0111] The sample analyzer provided by the application has the advantages that: the sample dispensing device is provided with the first sample needle and the second sample needle which can independently perform sample dispensing actions, and the same calibration data is used to calibrate the detection data obtained by detecting the sample dispensed by the first sample needle and the detection data obtained by detecting the sample dispensed by the second sample needle when the detection item corresponding to the sample dispensing action performed by the first sample needle and the detection item corresponding to the sample dispensing action performed by the second sample needle are the same detection item, so that the sample dispensing actions of the same detection item can be performed by the first sample needle and the second sample needle, the detection efficiency of the sample analyzer is improved, and the phenomenon that one sample needle is too busy and the other sample needle is idle is avoided; the same calibration data is used to calibrate the sample dispensing actions of the same detection item performed by the first sample needle and the second sample needle, so that the calibration of the items for each needle is not needed, the calibration cost is reduced, and the calibration efficiency is improved, and the detection efficiency, the calibration cost and the calibration efficiency are well balanced. BRIEF DESCRIPTION OF DRAWINGS

[0112] In order to more clearly illustrate the technical solutions in the embodiments of the application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description only show some embodiments of the application, and for those skilled in the art, other drawings can also be obtained from the structures shown in the drawings without any creative effort.

[0113] Figure 1 is a component schematic diagram of the sample analyzer provided by the first embodiment of the application;

[0114] Figure 2 is a structure schematic diagram of the sample analyzer provided by the first embodiment of the application;

[0115] Figure 3 is a liquid path schematic diagram of the first sample dispensing assembly provided by the first embodiment of the application;

[0116] Figure 4 is a liquid path schematic diagram of the second sample dispensing assembly provided by the first embodiment of the application;

[0117] Figure 5 is a schematic diagram of a liquid path of a sample dispensing device provided by an embodiment six of the present application;

[0118] Figure 6 is a schematic diagram of a structure of a sample analyzer provided by an embodiment twelve of the present application.

[0119] BRIEF DESCRIPTION OF DRAWINGS 10, sample analyzer; 100, sample dispensing device; 110, first sample dispensing assembly; 111, first sample needle; 112, first suction power component; 113, first cleaning driving component; 114, first cleaning control valve; 115, first liquid path; 116, third cleaning control valve; 117, first sample adding control valve; 118, third liquid path; 119, fourth liquid path; 120, second sample dispensing assembly; 121, second sample needle; 122, second suction power component; 123, second cleaning driving component; 124, second cleaning control valve; 125, second liquid path; 126, fourth cleaning control valve; 127, second sample adding control valve; 128, fifth liquid path; 129, sixth liquid path; 200, reagent dispensing device; 210, first reagent dispensing assembly; 220, second reagent dispensing assembly; 300, sample detection device; 400, controller; 500, magnetic separation device; 600, sample management device; 700, sample conveying device; 800, reagent storage device; 900, reaction device; 101, substrate dispensing device; 102, reaction container providing device; 103, reaction container recycling device; 104, transfer device; 20, cleaning liquid supply device. DETAILED DESCRIPTION

[0120] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative work are within the protection scope of the present application.

[0121] In addition, the technical solutions in each embodiment can be combined with each other, but it must be based on that a person of ordinary skill in the art can realize. When the combination of technical solutions appears contradictory or unachievable, it should be considered that the combination of technical solutions does not exist, and is not within the protection scope of the present application.

[0122] The embodiments of the present application are suitable for a sample analyzer which needs to pipette the same target liquid through at least two needles, and the target liquid includes but is not limited to sample, reagent, etc.

[0123] Embodiment one:

[0124] AsFigures 1 to 4 As shown in the figure, the sample analyzer 10 provided by the embodiment of the present application comprises a sample dispensing device 100 and a sample detecting device 300. The sample dispensing device 100 is used to perform the following sample dispensing action: sucking sample from a sample container and dispensing at least part of the sucked sample into a reaction container. The reaction container is used to provide a reaction site for the sample. The sample detecting device 300 is used to detect a to-be-detected liquid made at least from the sample.

[0125] As an implementation, the sample dispensing device 100 comprises a first sample dispensing assembly 110 and a second sample dispensing assembly 120. The first sample dispensing assembly 110 and the second sample dispensing assembly 120 are respectively used to perform the following sample dispensing action: sucking sample from a sample container and dispensing at least part of the sucked sample into a reaction container. The first sample dispensing assembly 110 and the second sample dispensing assembly 120 are two dispensing assemblies which can independently perform the sample dispensing action at least in part. That is, the components with the same function of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are not the same components. For example, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can share some components and do not share at least some components. Alternatively, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can not share any components. In this embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can be used to perform the sample dispensing action. Thus, when a batch of samples need to be detected by the sample analyzer 10, the sample dispensing action of a part of the samples can be performed by the first sample dispensing assembly 110 and the sample dispensing action of another part of the samples can be performed by the second sample dispensing assembly 120. Thus, the dispensing efficiency of the batch of samples is improved, and the detection efficiency of the whole machine is improved.

[0126] As an implementation, the first sample dispensing assembly 110 comprises a first sample needle 111 and the second sample dispensing assembly 120 comprises a second sample needle 121. The first sample needle 111 and the second sample needle 121 are two sample needles which can independently perform the sample dispensing action. The first sample needle 111 and the second sample needle 121 are two different sample needles. Here, different sample needles mainly refer to different needles, but do not refer to different shapes and sizes of the two needles. On the contrary, the shapes and sizes of the two needles can be the same. In this embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 do not share the sample needle. Thus, the sample dispensing device 100 has at least two sample needles which can work at the same time (here, working at the same time can mean that the two sample needles perform the same action at the same time; or one sample needle performs one action and the other sample needle performs another action). Thus, the dispensing efficiency of the batch of samples is improved.

[0127] As an implementation, the sample analyzer 10 further comprises a reagent dispensing device 200, which is configured to perform a reagent dispensing action of sucking reagent from a reagent container and dispensing at least part of the sucked reagent into a reaction container. The sample detecting device 300 is configured to detect a to-be-detected liquid made of at least a sample dispensed by the sample dispensing device 100 and reagent dispensed by the reagent dispensing device 200. The sample analyzer 10 of the present implementation is applicable to a scenario where reagent is dispensed into a reaction container by the reagent dispensing device 200; of course, as an alternative implementation, the sample analyzer 10 can not be provided with the reagent dispensing device 200 in a specific application, which is applicable to a scenario where reagent is pre-stored in a reaction container.

[0128] As an implementation, the sample analyzer 10 further comprises a controller 400, which is configured to control at least the first sample dispensing assembly 110, the second sample dispensing assembly 120, the reagent dispensing device 200, and the sample detecting device 300 to work.

[0129] As an implementation, the controller 400 is configured to perform a first detection process of controlling the first sample dispensing assembly 110 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detecting device 300 to detect a to-be-detected liquid made of at least a sample dispensed by the first sample dispensing assembly 110 and reagent dispensed by the reagent dispensing device 200, obtaining first detection data according to detection information fed back by the sample detecting device 300, and obtaining a first detection result according to the first detection data and first calibration data. The controller 400 is further configured to perform a second detection process of controlling the second sample dispensing assembly 120 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detecting device 300 to detect a to-be-detected liquid made of at least a sample dispensed by the second sample dispensing assembly 120 and reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detecting device 300, and obtaining a second detection result according to the second detection data and second calibration data. The difference between the first detection process and the second detection process mainly lies in the sample dispensing assembly used to perform a sample dispensing action, which is embodied in that the sample dispensing action of the first detection process is performed by the first sample dispensing assembly 110, and the sample dispensing action of the second detection process is performed by the second sample dispensing assembly 120. Both the first detection process and the second detection process need to calibrate detection data with calibration data to obtain a final detection result.

[0130] As an implementation, when the detection item executed by the first detection procedure is the same as the detection item executed by the second detection procedure, the first calibration data and the second calibration data are the same calibration data. Here, the same detection item refers to two detection items using the same detection method to detect the same target parameter. The same detection method specifically refers to the same detection principle and detection steps, but the execution components performing the same steps can be different. In the present embodiment, the first sample needle 111 and the second sample needle 121 can be used to perform sample dispensing actions of the same detection item, that is, the first detection procedure and the second detection procedure can be used to perform the same detection item on two samples. Thus, when batch detection of a certain detection item is required, the first sample needle 111 can be controlled to perform sample dispensing actions of a part of the detection item, the second sample needle 121 can be controlled to perform sample dispensing actions of another part of the detection item, and the first sample needle 111 and the second sample needle 121 can be controlled to work simultaneously or alternately, so that the first sample needle 111 and the second sample needle 121 can be fully utilized to improve the detection efficiency of the sample analyzer 10. In addition, since the first sample needle 111 and the second sample needle 121 perform sample dispensing actions of the same detection item using the same calibration data for calibration, it is not necessary to perform item calibration for both the first sample needle 111 and the second sample needle 121, thereby reducing the calibration cost and improving the calibration efficiency, and the detection efficiency, calibration cost and calibration efficiency are well balanced.

[0131] As an implementation, the first sample dispensing assembly 110 further comprises a first suction power component 112, which is used to provide driving force for the first sample needle 111 to perform suction actions. The second sample dispensing assembly 120 further comprises a second suction power component 122, which is used to provide driving force for the second sample needle 121 to perform suction actions. The first suction power component 112 is the power source for the first sample dispensing assembly 110 to perform suction actions, and the second suction power component 122 is the power source for the second sample dispensing assembly 120 to perform suction actions. The first suction power component 112 and the second suction power component 122 can both be syringes or plunger pumps.

[0132] As an implementation, the first sample dispensing assembly 110 further comprises a first movement power component, which is used to drive the first sample needle 111 to move in space so as to move the first sample needle 111 to different stations, such as standby stations, sample suction stations, dispensing stations, and cleaning stations.

[0133] As an implementation, the second sample dispensing assembly 120 further comprises a second motion driving component for driving the second sample needle 121 to move in space so as to move the second sample needle 121 to different stations, such as standby station, sample suction station, sample dispensing station, cleaning station, etc.

[0134] As an implementation, the first sample dispensing assembly 110 further comprises a first cleaning driving component 113 for driving the cleaning liquid provided by the cleaning liquid supply device 20 to flush the first sample needle 111; and the second sample dispensing assembly 120 further comprises a second cleaning driving component 123 for driving the cleaning liquid provided by the cleaning liquid supply device 20 to flush the second sample needle 121.

[0135] As an implementation, the first sample dispensing assembly 110 further comprises a first cleaning control valve 114 and a first liquid path 115 connected between the first cleaning driving component 113 and the first dispensing driving component 112, the first cleaning driving component 113 is configured to drive the cleaning liquid provided by the cleaning liquid supply device 20 to flow towards the first liquid path 115, and the first cleaning control valve 114 is arranged on the first liquid path 115 to control the opening and closing of the first liquid path 115; and the second sample dispensing assembly 120 further comprises a second cleaning control valve 124 and a second liquid path 125 connected between the second cleaning driving component 123 and the first dispensing driving component 112, the second cleaning driving component 123 is configured to drive the cleaning liquid provided by the cleaning liquid supply device 20 to flow towards the second liquid path 125, and the second cleaning control valve 124 is arranged on the second liquid path 125 to control the opening and closing of the second liquid path 125.

[0136] As an implementation, the first cleaning driving component 113 and the second cleaning driving component 123 are the same component, the first cleaning control valve 114 and the second cleaning control valve 124 are the same component, and the first liquid path 115 and the second liquid path 125 are the same liquid path. Alternatively, the first cleaning driving component 113 and the second cleaning driving component 123 can be two different components, the first cleaning control valve 114 and the second cleaning control valve 124 can be two different components, and the first liquid path 115 and the second liquid path 125 can be two different liquid paths.

[0137] As an implementation form, the first sample dispensing assembly 110 further comprises a third cleaning control valve 116, a first sample adding control valve 117, a third liquid path 118 and a fourth liquid path 119, the third liquid path 118 is connected between the first cleaning driving part 113 and the first sample needle 111, the fourth liquid path 119 is connected between the first suction driving part 112 and the first sample needle 111, the third cleaning control valve 116 is arranged on the third liquid path 118 to control the opening and closing of the third liquid path 118, and the first sample adding control valve 117 is arranged on the fourth liquid path 119 to control the opening and closing of the fourth liquid path 119. The second sample dispensing assembly 120 further comprises a fourth cleaning control valve 126, a second sample adding control valve 127, a fifth liquid path 128 and a sixth liquid path 129, the fifth liquid path 128 is connected between the second cleaning driving part 123 and the second sample needle 121, the sixth liquid path 129 is connected between the first suction driving part 112 and the second sample needle 121, the fourth cleaning control valve 126 is arranged on the fifth liquid path 128 to control the opening and closing of the fifth liquid path 128, and the second sample adding control valve 127 is arranged on the sixth liquid path 129 to control the opening and closing of the sixth liquid path 129.

[0138] As an implementation form, the deviation of the sample dispensing precision of the first sample dispensing assembly 110 and the sample dispensing precision of the second sample dispensing assembly 120 is less than or equal to a first preset value, the first preset value is greater than or equal to zero and less than or equal to 5%, so that the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action are basically consistent, thereby facilitating to reduce the influence on the sample detection result when the first sample dispensing assembly 110 and the second sample dispensing assembly 120 respectively perform the sample dispensing action, and further facilitating to use the same calibration data when the first sample needle 111 and the second sample needle 121 perform the sample dispensing action of the same detection item, thereby improving the accuracy of the detection result.

[0139] As an implementation form, the first preset value is less than or equal to 2%, so as to more facilitate to reduce the difference between the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action, thereby facilitating to ensure the consistency of the sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, and further facilitating to further improve the accuracy of the detection result when the first sample needle 111 and the second sample needle 121 perform the sample dispensing action of the same detection item by using the same calibration data.

[0140] As an implementation, the sample analyzer 10 further comprises a reaction device 900 for carrying the reaction container to incubate the sample and the reagent in the reaction container. The controller 400 is further configured to control the same reagent dispensing device 200 to perform the reagent dispensing action in the first detection process and the reagent dispensing action in the second detection process respectively, control the same reaction device 900 to incubate the sample and the reagent in the first detection process and the sample and the reagent in the second detection process respectively, and control the same sample detection device 300 to detect the sample liquid in the first detection process and the sample liquid in the second detection process respectively. In this implementation, the first detection process and the second detection process share the reagent dispensing device 200, the reaction device 900 and the sample detection device 300, which is conducive to ensuring the consistency of the reagent system, the reaction system and the detection system in the first detection process and the second detection process. Thus, as long as the sample amount dispensing difference of the sample dispensing system (i.e., the first sample dispensing assembly 110 and the second sample dispensing assembly 120) is reduced, the consistency of the detection results can be ensured.

[0141] As an implementation, the reagent dispensing device 200 comprises a first reagent dispensing assembly comprising a first reagent needle and a third dispensing power component for driving the first reagent needle to suck the reagent from the reagent container and drive the first reagent needle to dispense at least part of the sucked reagent into the reaction container. The reaction device 900 comprises a first reaction disc for carrying the reaction container to incubate the sample and the reagent. The detection device comprises a first light receiving component for performing optical detection on the sample liquid in the reaction container. The controller 400 is further configured to control the same third dispensing power component to drive the same first reagent needle to perform the reagent dispensing action in the first detection process and the reagent dispensing action in the second detection process respectively, control the same first reaction disc to incubate the sample and the reagent in the first detection process and the sample and the reagent in the second detection process, and control the same first light receiving component to perform the optical detection in the first detection process and the optical detection in the second detection process respectively. In this implementation, the first detection process and the second detection process share the reagent needle, the reagent dispensing power component, the first reaction disc and the first light receiving component, which is conducive to ensuring the consistency of the reagent system, the reaction system and the detection system in the first detection process and the second detection process.

[0142] As an implementation, the sample analyzer 10 further comprises a reagent storage device 800 for storing the reagent container, and the reagent dispensing device 200 is configured to suck the reagent from the reagent container at the reagent suction position in the reagent storage device 800. Of course, in specific applications, as an alternative implementation, the reagent storage device 800 can also not be provided in the sample analyzer 10, for example, the reagent container can be placed at the reagent suction position by the operator.

[0143] As an embodiment, the above-mentioned sample analyzer 10 is an immunoassay analyzer. The immunoassay analyzer is used to detect immune-related parameters in blood samples. Prior to the present application, immunoassay analyzers in the related art either used a single needle system to perform the distribution of all samples in the immunoassay analyzer, or used a multi-needle system to perform the distribution of samples for different test items separately, or used a multi-needle system that required separate clinical project calibration to perform the distribution of different samples separately. These solutions cannot take into account the design requirements of the immunoassay analyzer for high detection efficiency, low calibration cost, and high calibration efficiency. In the immunoassay analyzer provided in this embodiment, the first sample needle 111 and the second sample needle 121 can be used to detect the same test item and can share the same calibration data when detecting the same test item. In this way, on the one hand, the purpose of improving the efficiency of immunoassay can be achieved by the parallel operation of the first sample needle 111 and the second sample needle 121. On the other hand, since clinical project calibration is not required for both the first sample needle 111 and the second sample needle 121, the multi-needle calibration cost of the immunoassay analyzer is reduced and the calibration efficiency is improved. Of course, in specific applications, the type of sample analyzer 10 is not limited to this. For example, as an alternative embodiment, the sample analyzer 10 can also be a biochemical analyzer, a routine blood cell analyzer, or a coagulation analyzer, etc. That is, the efficient and low-cost multi-sample needle system of this embodiment can be used not only for immunoassay analyzers, but also for other analyzers such as biochemical analyzers, routine blood cell analyzers, or coagulation analyzers.

[0144] As an embodiment, the detection items performed by the immunoassay analyzer include at least immunoluminescence detection items. The goal of immunoluminescence detection is to detect the content of a certain specific antigen or antibody in a sample. The reaction container is at least used to carry the sample and the reagent to produce the antigen and antibody binding reaction. The sample detection device 300 is used to detect the optical signal of the test liquid. Due to the presence of various impurities in the sample, some impurities, such as endogenous enzymes contained in the blood sample itself, will affect the final detection system (i.e., the test liquid to be tested at the end), thereby affecting the accuracy of the test results; therefore, the execution process of the immunoluminescence detection needs to first purify the target antigen or target antibody, and then obtain the level (i.e., content) of the target antigen or target antibody in the sample through luminescence detection of the marker. In order to detect the level of the target antigen or target antibody in the sample, this embodiment converts the concentration of the target antigen or target antibody into a physical quantity of luminescence. Since the antigen or antibody itself does not have the ability to luminesce, the luminescence conversion can be performed by an antibody with a luminescent marker or an antigen with a luminescent marker.

[0145] As an embodiment, the reaction container is used to provide a reaction site for the sample and the reagent to produce an antigen-antibody binding reaction between the target antigen in the sample and the antibody in the reagent or between the target antibody in the sample and the antigen in the reagent to produce a third reaction solution containing at least a first antigen-antibody binding body. In this embodiment, the target of the at least one sample detection item is to detect the content of the target antigen (a certain specific antigen) or the target antibody (a certain specific antibody) in the sample. When the target of one sample detection item is to detect the target antigen in the sample, the sample contains the target antigen and the reagent contains the antibody, and the first antigen-antibody binding body is formed by the antigen-antibody binding reaction between the target antigen in the sample and the antibody in the reagent. When the target of one sample detection item is to detect the target antibody in the sample, the sample contains the target antibody and the reagent contains the antibody, and the first antigen-antibody binding body is formed by the antigen-antibody binding reaction between the target antibody in the sample and the antigen in the reagent.

[0146] As an embodiment, the sample analyzer 10 further comprises a magnetic separation device 500 and a substrate dispensing device 101. The reagent dispensing device 200 performs a reagent dispensing action, which includes: sucking the magnetic bead reagent from the first reagent container and dispensing it into the reaction container, and sucking the second marker reagent from the second reagent container and dispensing it into the reaction container. The reaction device 900 is used to incubate the reaction container to produce a third reaction solution containing at least the sample, the magnetic bead reagent, and the second marker reagent. The magnetic separation device 500 is used to perform a magnetic separation and washing operation on the third reaction solution to produce a fourth reaction solution. The substrate dispensing device 101 is used to perform a substrate dispensing action, which includes: sucking the luminescent substrate reagent from the substrate reagent container, and dispensing at least part of the sucked luminescent substrate reagent into the reaction container to produce a to-be-tested solution from the fourth reaction solution and the luminescent substrate reagent. The sample detection device 300 is used to detect the luminescent intensity of the to-be-tested solution. The magnetic bead reagent is a reagent containing magnetic beads. The second marker reagent is an antibody reagent with a luminescent marker or an antigen reagent with a luminescent marker. Before the magnetic separation and washing operation, the sample and the reagent first perform an antigen-antibody binding reaction. During the magnetic separation and washing operation, the operations of magnetic adsorption, liquid suction, addition of a separation liquid, mixing, and incubation are performed. The magnetic separation and washing operation is mainly used to wash away the impurities in the third reaction solution while retaining part of the to-be-tested solution to obtain a purified fourth reaction solution. The liquid treated by the magnetic separation device 500 includes a clear liquid and a magnetic bead liquid. In an embodiment, the clear liquid is treated as waste liquid, and the magnetic bead liquid forms the fourth reaction solution. In this embodiment, the magnetic bead reagent and the second marker reagent are two reagents separately packaged in two reagent containers. Of course, as an alternative embodiment, the magnetic bead reagent and the second marker reagent can be integrated into one reagent and packaged in the same reagent container in specific applications.

[0147] As an implementation, the substrate dispensing device 101 is used to perform the substrate dispensing action on the reaction container located in the magnetic separation device 500, and the substrate dispensing device 101 and the reagent dispensing device 200 are two different dispensing devices. Of course, in specific applications, as an alternative implementation, the reagent dispensing device 200 can also be used to perform the substrate dispensing action on the reaction container located in the reaction device 900, that is, the substrate dispensing device 101 and the reagent dispensing device 200 can also be the same dispensing device.

[0148] As an implementation, the controller 400 is further configured to control the same magnetic separation device 500 to perform the magnetic separation washing operation in the first detection process and the magnetic separation washing operation in the second detection process, respectively, and control the same substrate dispensing device 101 to perform the substrate dispensing action in the first detection process and the substrate dispensing action in the second detection process, respectively. In this implementation, the first detection process and the second detection process share the magnetic separation device 500 and the substrate dispensing device 101 in addition to the reagent dispensing device 200, the reaction device 900 and the sample detection device 300, which helps to ensure the consistency of the reagent system, the reaction system, the magnetic separation system, the substrate system and the detection system in the first detection process and the second detection process, effectively avoiding the influence of the reagent system, the reaction system, the magnetic separation system, the substrate system and the detection system on the detection result. In this way, as long as the sample dispensing system is made consistent as much as possible, the consistency of the detection result can be ensured.

[0149] As an implementation, the third pipetting power component is configured to drive the first reagent needle to aspirate the magnetic bead reagent containing magnetic beads from the first reagent container and dispense the magnetic bead reagent into the reaction container, and to aspirate the second label reagent containing an enzyme from the second reagent container and dispense the second label reagent into the reaction container. The first reaction disc is configured to incubate the sample, the magnetic bead reagent, and the second label reagent in the reaction container. The magnetic separation device 500 is configured to perform a magnetic separation and washing action on the liquid in the reaction container after at least the sample, the magnetic bead reagent, and the second label reagent are incubated. The substrate dispensing device 101 includes a substrate needle and a fourth pipetting power component configured to drive the substrate needle to perform a substrate dispensing action of aspirating the luminescent substrate reagent from the substrate container and dispensing at least part of the aspirated luminescent substrate reagent into the reaction container to prepare the to-be-tested liquid. The controller 400 is further configured to: control the same third pipetting power component to drive the same first reagent needle to perform the reagent dispensing action of the magnetic bead reagent in the first detection process and the reagent dispensing action of the magnetic bead reagent in the second detection process, respectively; control the same third pipetting power component to drive the same first reagent needle to perform the reagent dispensing action of the second label reagent in the first detection process and the reagent dispensing action of the second label reagent in the second detection process, respectively; control the same first reaction disc to incubate the sample, the magnetic bead reagent, and the second label reagent in the first detection process and the sample, the magnetic bead reagent, and the second label reagent in the second detection process; control the same magnetic separation device 500 to perform a magnetic separation and washing action on the liquid in the reaction container after at least the sample, the magnetic bead reagent, and the second label reagent are incubated in the first detection process and the second detection process; control the same fourth pipetting power component to drive the same substrate needle to perform the substrate dispensing action in the first detection process and the substrate dispensing action in the second detection process, respectively; and control the same first light receiving component to perform optical detection in the first detection process and optical detection in the second detection process, respectively.

[0150] As an embodiment, the first antigen-antibody binding body contained in the third reaction solution is formed by sandwiching the antigen and the antibody. For example, if the content of the target antigen in the sample is to be detected, the magnetic bead reagent distributed by the reagent distribution device 200 carries the antibody, and the second marker reagent is the antibody reagent carrying the luminescent marker. The target antigen in the sample is sandwiched between the antibody of the magnetic bead reagent and the antibody of the second marker reagent. In this scheme, the sample has an antigen on the cell surface, the magnetic bead has an antibody on the surface, and the second marker reagent has an antibody. The target antigen in the sample can be specifically combined with the magnetic bead carrying the specific antibody and the antibody carrying the second luminescent marker, thereby forming the first antigen-antibody binding body of magnetic bead-target antigen-luminescent marker antibody. If the content of the target antibody in the sample is to be detected, the magnetic bead reagent distributed by the reagent distribution device 200 carries the antigen, and the second marker reagent is the antigen reagent carrying the luminescent marker.

[0151] As an embodiment, when the target antigen in the sample needs to be detected, the sandwich method immunoluminescence detection process includes: in the initial mixing process of the sample and the reagent, the target antigen is first combined with the magnetic bead carrying the specific antibody, and then the target antigen is specifically combined with the antibody carrying the luminescent marker in the reagent, at this time, the system of magnetic bead antibody-target antigen-luminescent marker antibody is generated (i.e. the first antigen-antibody binding body described above). After the system of magnetic bead antibody-target antigen-luminescent marker antibody is generated, the magnetic separation and cleaning operation step is entered. Before the magnetic separation and cleaning operation step, the reaction system contains impurities, and the magnetic separation and cleaning operation can clean away the impurities by changing the liquid and re-dispersing, while retaining the target antigen to be detected in the reaction container, thereby realizing the purification of the reaction solution. Finally, the fourth reaction solution after purification is mixed with the luminescent substrate reagent, and the second luminescent substrate reagent emits light under the catalysis of the second luminescent marker, and is collected and counted by the sample detection device 300 (such as a luminometer, etc.). The controller 400 calculates the concentration value of the corresponding target antigen according to the data fed back by the sample detection device 300, thereby obtaining the target antigen level of the corresponding sample to help clinical judgment.

[0152] Of course, in a specific application, the antigen-antibody conjugate contained in the third reaction solution is not limited to that formed by sandwiching the antigen and the antibody, and in an alternative embodiment, the antigen-antibody conjugate contained in the third reaction solution can also be formed by competition between the antigen and the antibody. In this alternative, the antigen-antibody conjugate contained in the third reaction solution includes: a first antigen-antibody conjugate formed by the target antigen in the sample and the antibody on the surface of the magnetic bead in the magnetic bead reagent, and a second antigen-antibody conjugate formed by the antigen in the second marker reagent and the antibody on the surface of the magnetic bead in the magnetic bead reagent. Since the number of antibodies on the magnetic bead is limited, the target antigen in the sample and the antigen in the second marker reagent form a competitive relationship, i.e., the luminescence value is inversely proportional to the concentration of the target in the sample, and the concentration of the target antigen in the sample can be inversely calculated by the measured luminescence value.

[0153] As an embodiment, the execution process of a detection item in the immunoassay instrument includes: adding the sample, adding the magnetic bead reagent and the second marker reagent to form a first mixed solution, mixing and incubating the first mixed solution to obtain a third reaction solution, magnetically separating and washing the third reaction solution to obtain a fourth reaction solution, adding a luminescent substrate reagent to the fourth reaction solution to obtain a second mixed solution, mixing and incubating the second mixed solution to obtain a to-be-measured solution, optically measuring the to-be-measured solution to obtain a detection result.

[0154] As an embodiment, the sample analyzer 10 also includes a distribution volume detection device, and the controller 400 is further configured to execute the following sample loading calibration process: controlling the first sample dispensing component 110 to absorb the sample loading calibrator and distribute it into the reaction container, and controlling the distribution volume detection device to detect the distribution volume of the first calibrator distributed into the reaction container by the first sample dispensing component 110; controlling the second sample dispensing component 120 to absorb the sample loading calibrator and distribute it into the reaction container, and controlling the distribution volume detection device to detect the distribution volume of the second calibrator distributed into the reaction container by the second sample dispensing component 120; and correcting the sample distribution volume of the first sample dispensing component 110 in performing the sample distribution action and / or the sample distribution volume of the second sample dispensing component 120 in performing the sample distribution action according to the first calibrator distribution volume and the second calibrator distribution volume, so that the deviation between the sample distribution accuracy of the first sample dispensing component 110 and the sample distribution accuracy of the second sample dispensing component 120 is less than or equal to a first preset value. In this embodiment, the sample dispensing amount of the first sample dispensing component 110 and / or the sample dispensing amount of the second sample dispensing component 120 during the sample dispensing action are corrected through a sample loading calibration process, thereby effectively reducing the accuracy difference between the sample dispensing amount of the first sample dispensing component 110 and the sample dispensing amount of the second sample dispensing component 120, thereby facilitating the consistency of the sample amount dispensed by the first sample dispensing component 110 and the sample amount dispensed by the second sample dispensing component 120. This embodiment, which ensures the consistency of the sample amount dispensed by the first sample dispensing component 110 and the sample amount dispensed by the second sample dispensing component 120 through a sample loading calibration process, is primarily suitable for high-end sample analyzers 10 with high accuracy requirements. Of course, in specific applications, in alternative implementation schemes, the sample addition calibration process may not be set in the mid-to-low-end sample analyzer 10, allowing a certain difference in the distribution volume of the first sample dispensing component 110 and the second sample dispensing component 120, and allowing the test results to be biased due to the deviation in the sample distribution volume. However, if it is within the clinically permitted range, no processing is required to ensure that it is acceptable to the mid-to-low-end sample analyzer 10.

[0155] This embodiment designs a sample loading calibration correction scheme to address the differences in the distribution accuracy of multiple sample needle channels. The sample loading calibration process is different from the calibration scheme in the related art where each clinical project is calibrated separately for each needle. The sample loading calibration process is to perform sample loading calibration correction on the first sample dispensing component 110 and / or the second sample dispensing component 120 after preparing the corresponding sample loading calibrators and calibration consumables to complete the sample loading calibration test, correction parameter calculation and configuration, and sample loading calibration verification. After the sample loading calibration is successful, there is no need to perform multiple separate calibrations for multiple sample needles for the clinical project.

[0156] As an implementation, the correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first calibrant dispensing amount and the second calibrant dispensing amount includes: calculating a first deviation value of the second calibrant dispensing amount relative to the first calibrant dispensing amount, and correcting the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first deviation value. In the sample dispensing calibration process, the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is calibrated based on the first calibrant dispensing amount of the first sample dispensing assembly 110, and the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action remains unchanged. In this implementation, the sample dispensing amount of one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 in the sample dispensing action is calibrated based on the sample dispensing amount of the other in the sample dispensing action. Since only one operation is required, the sample dispensing calibration process can not only reduce the difference between the sample dispensing accuracy of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, but also reduce the amount of calculation in the calibration process.

[0157] As an implementation, the above-mentioned correction of the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first deviation value comprises: obtaining a first correction parameter according to the first deviation value, and calculating the corrected sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action based on the target sample dispensing amount of the sample dispensing device 100 actually required to be dispensed to the reaction container in the sample dispensing action and the first correction parameter. That is, the above-mentioned correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first calibration sample dispensing amount and the second calibration sample dispensing amount comprises: calculating the first deviation value of the second calibration sample dispensing amount relative to the first calibration sample dispensing amount, obtaining a first correction parameter according to the first deviation value, and calculating the corrected sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action based on the target sample dispensing amount of the sample dispensing device 100 actually required to be dispensed to the reaction container in the sample dispensing action and the first correction parameter. The sample dispensing amount of the second sample dispensing assembly 120 remains unchanged. Specifically, assuming that the target dispensing amount of the sample dispensing device 100 in the sample dispensing action is V0, the first calibration sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing calibration process is V1, and the second calibration sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing calibration process is V2, after the sample dispensing calibration process, the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action remains unchanged, and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is modified to V0+(V2-V1)K, wherein K is a sample dispensing transfer coefficient of a specific volume, which is affected by the instrument, the sample dispensing calibration sample, the sample dispensing volume, and the sample dispensing deviation between the sample needles. The sample dispensing transfer coefficient K can be regarded as a constant within a certain sample dispensing amount range.

[0158] In the above-mentioned scheme, the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is calibrated based on the first calibration sample dispensing amount of the first sample dispensing assembly 110, so as to control the accuracy difference between the sample dispensing amounts of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 in the sample dispensing action within a small range.

[0159] Of course, in specific applications, the correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first calibrant dispensing amount and the second calibrant dispensing amount is not limited to the above-mentioned calibration scheme based on the first calibrant dispensing amount of the first sample dispensing assembly 110. For example, as a first alternative embodiment of the above-mentioned calibration of the sample dispensing amount of the second sample dispensing assembly 120 based on the first calibrant dispensing amount, the above-mentioned correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first calibrant dispensing amount and the second calibrant dispensing amount can also include: calculating a second deviation value of the first calibrant dispensing amount relative to the second calibrant dispensing amount, and correcting the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action according to the second deviation value. In this alternative embodiment, the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action is calibrated based on the second calibrant dispensing amount of the second sample dispensing assembly 120, and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action remains unchanged, so that the purpose of reducing the difference in dispensing accuracy between the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can also be achieved through the sample addition calibration process.

[0160] As a further embodiment of the first alternative embodiment of the calibration of the sample dispensing amount of the second sample dispensing assembly 120 based on the first calibrant dispensing amount, the above-mentioned correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the first calibrant dispensing amount and the second calibrant dispensing amount includes: calculating a second deviation value of the first calibrant dispensing amount relative to the second calibrant dispensing amount, obtaining a second correction parameter according to the second deviation value, and calculating a corrected sample dispensing amount of the second sample dispensing assembly 120 based on the target dispensing amount of the sample to be dispensed by the sample dispensing device 100 to the reaction vessel in the sample dispensing action and the second correction parameter, while the sample dispensing amount of the first sample dispensing assembly 110 remains unchanged. Specifically, assuming that the target dispensing amount of the sample dispensing device 100 in the sample dispensing action is V0, the first calibrant dispensing amount of the first sample dispensing assembly 110 in the sample addition calibration process is V1, and the second calibrant dispensing amount of the second sample dispensing assembly 120 in the sample addition calibration process is V2, then after the sample addition calibration process, the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action remains unchanged, and the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action is modified to V0+(V1-V2)K, where K is a sample addition transfer coefficient of a specific volume.

[0161] Alternatively, as the second alternative implementation of calibrating the sample dispensing amount of the second sample dispensing assembly 120 based on the first calibrant dispensing amount, the correction of the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action based on the first calibrant dispensing amount and the second calibrant dispensing amount includes: calculating a third deviation value of the first calibrant dispensing amount relative to a reference amount, calculating a fourth deviation value of the second calibrant dispensing amount relative to the reference amount, correcting the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action based on the third deviation value, and correcting the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action based on the fourth deviation value; wherein the reference amount is the target dispensing amount of the sample actually required to be dispensed by the sample dispensing device 100 to the reaction vessel in the sample dispensing action, or the reference amount has a preset difference with the target dispensing amount of the sample actually required to be dispensed by the sample dispensing device 100 to the reaction vessel in the sample dispensing action. In this alternative implementation, the sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 in the sample dispensing action are calibrated based on the reference amount respectively, which can also achieve the purpose of reducing the difference in accuracy of the sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120.

[0162] As a further implementation of the second alternative implementation of calibrating the sample dispensing amount of the second sample dispensing assembly 120 based on the first calibrant dispensing amount, the above-mentioned correcting the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action based on the first calibrant dispensing amount and the second calibrant dispensing amount includes: calculating a third deviation value of the first calibrant dispensing amount relative to a reference amount, obtaining a third correction parameter based on the third deviation value, and calculating the corrected sample dispensing amount of the first sample dispensing assembly 110 based on a target dispensing amount of sample to be dispensed by the sample dispensing device 100 to the reaction vessel in the sample dispensing action and the third correction parameter; calculating a fourth deviation value of the second calibrant dispensing amount relative to the reference amount, obtaining a fourth correction parameter based on the fourth deviation value, and calculating the corrected sample dispensing amount of the second sample dispensing assembly 120 based on the target dispensing amount and the fourth correction parameter; wherein the reference amount is the target dispensing amount, or the reference amount has a preset difference with the target dispensing amount. Assuming that the target sample dispensing amount of the sample dispensing device 100 in the sample dispensing action is V0, the first calibrant dispensing amount of the first sample dispensing assembly 110 in the sample dispensing calibration process is V1, and the second calibrant dispensing amount of the second sample dispensing assembly 120 in the sample dispensing calibration process is V2, then after the sample dispensing calibration process, the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action is modified to V0+(V1-V0)K, and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is modified to V0+(V2-V0)K, wherein K is the sample transfer coefficient of a specific volume.

[0163] As an implementation, the dispensing amount detection device is a second optical detection device, and the sample calibration liquid is a first labeled reagent with a luminescent label. The sample analyzer 10 further comprises a substrate dispensing device 101 for dispensing a luminescent substrate reagent into the reaction vessel. The above-mentioned control of the first sample dispensing assembly 110 to aspirate the sample calibration liquid and dispense it into the reaction vessel, and the control of the dispensing amount detection device to detect the first calibration liquid dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction vessel, comprises: control of the first sample dispensing assembly 110 to aspirate the first labeled reagent and dispense it into the reaction vessel, control of the substrate dispensing device 101 to dispense the luminescent substrate reagent into the reaction vessel, and control of the second optical detection device to detect the luminescent intensity of a first reaction solution made of at least the first labeled reagent dispensed by the first sample dispensing assembly 110 into the reaction vessel and the luminescent substrate reagent dispensed by the substrate dispensing device 101 into the reaction vessel, to obtain the first calibration liquid dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction vessel. The above-mentioned control of the second sample dispensing assembly 120 to aspirate the sample calibration liquid and dispense it into the reaction vessel, and the control of the dispensing amount detection device to detect the second calibration liquid dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction vessel, comprises: control of the second sample dispensing assembly 120 to aspirate the first labeled reagent and dispense it into the reaction vessel, control of the substrate dispensing device 101 to dispense the luminescent substrate reagent into the reaction vessel, and control of the second optical detection device to detect the luminescent intensity of a second reaction solution made of at least the first labeled reagent dispensed by the second sample dispensing assembly 120 into the reaction vessel and the luminescent substrate reagent dispensed by the substrate dispensing device 101 into the reaction vessel, to obtain the second calibration liquid dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction vessel. After obtaining the first calibration liquid dispensing amount and the second calibration liquid dispensing amount, the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action are further corrected according to the first calibration liquid dispensing amount and the second calibration liquid dispensing amount, i.e., the deviation between the sample dispensing precision of the first sample dispensing assembly 110 and the sample dispensing precision of the second sample dispensing assembly 120 is less than or equal to the first preset value. In this embodiment, the sample dispensing amount of the first sample dispensing assembly 110 and / or the first sample dispensing assembly 110 is calibrated by using the immuno-luminescence method, which is conducive to fully utilizing the reaction system and detection system in the immuno-analyzer to perform the sample calibration process, without the need for additional new systems to perform the sample calibration process, thereby reducing the execution cost of the sample calibration process.

[0164] As an implementation, the second optical detection device used by the dispensing amount detection device is the same detection device as the sample detection device 300, that is, directly using the sample detection device 300 inside the immune analyzer as the dispensing amount detection device, so that the sample calibration process can be performed without additionally setting an optical detection device as a dispensing amount detection device. The implementation does not need to use other equipment, and the immune analyzer itself detection system can complete the quantification of the difference between the two sample needles, and the sample calibration process can be automatically executed. Of course, as an alternative implementation, the second optical detection device used by the dispensing amount detection device and the sample detection device 300 can also be set as two different detection devices, for example, an optical detection device can be built-in or externally connected to the sample analyzer 10 as a dispensing amount detection device.

[0165] As an implementation, the sample calibration process is different from the first detection process and the second detection process in at least one of the following: the components of the first label reagent are different from the components of the second label reagent, the concentration of the first label reagent is different from the concentration of the second label reagent, the dispensing amount of the first label reagent is different from the dispensing amount of the second label reagent, the dispensing amount of the luminescent substrate reagent is different, the incubation time is different, and the incubation temperature is different. In the luminescent immune reaction system, the factors affecting the final luminescence value intensity include not only the dispensing amount of the sample needle, but also the components of the label reagent, the concentration of the label reagent, the dispensing amount of the label reagent, the incubation temperature, the incubation time, and the injection amount of the luminescent substrate reagent. In order to ensure that the luminescence value can reflect the dispensing amount deviation of the sample needle without introducing interference from other aspects, a scheme can be used to highlight the dispensing amount deviation of the sample needle and weaken the influence of other factors, for example, because the components of the label reagent, the concentration of the label reagent, the dispensing amount of the label reagent, the incubation temperature, the incubation time, and the injection amount of the luminescent substrate reagent in the sample calibration process are unrelated to the components of the label reagent, the concentration of the label reagent, the dispensing amount of the label reagent, the incubation temperature, the incubation time, and the injection amount of the luminescent substrate reagent in the first detection process and the second detection process, the components of the label reagent, the concentration of the label reagent, and the dispensing amount of the label reagent in the sample calibration process can be designed with a large transfer coefficient as the target, and the incubation temperature, the incubation time, and the injection amount of the luminescent substrate reagent in the sample calibration process can be designed with a small transfer coefficient as the target.

[0166] As an implementation, in order to ensure that the luminescence value can reflect the deviation of the dispensing amount of the sample needle without introducing interference of other links, the following scheme can be used to highlight the deviation of the dispensing amount of the sample needle and eliminate the influence of other factors: (1) The formula and concentration of the first marker reagent in the sample adding calibration process are specially designed to make the sample adding transfer coefficient large, for example, at least above 0.7. The second marker reagent used in the sample adding calibration process is not the same as the second marker reagent used in the sample detection process (for example, the first detection process, the second detection process), and the formula and concentration are different, that is, a new marker reagent is designed for this method. (2) The transfer coefficient of other factors is designed to be as small as possible, at most not more than 0.1, for example, the luminescent substrate reagent injection amount. Since the luminescent substrate reagent injection amount used in the sample adding calibration process has nothing to do with the luminescent substrate reagent injection amount used in the immune detection project, the luminescent substrate reagent injection amount used is redesigned with the goal of small transfer coefficient. The design method can be, for example: when other factors are fixed, perform a gradient experiment of the luminescent substrate reagent injection amount, analyze the luminescence value and the transfer coefficient of the luminescent substrate reagent injection amount under different luminescent substrate reagent injection amounts, and select the luminescent substrate reagent injection amount that meets the requirements. In the experiment, the luminescent intensity under different luminescent substrate reagent injection amounts is shown in the figure. As can be seen from the figure, when the luminescent substrate reagent injection amount is in the interval of 130ul-150ul, the luminescent intensity is large and the curve is flat, that is, the luminescence value does not change with the change of the luminescent substrate reagent injection amount (the transfer coefficient is close to 0), so the luminescent substrate reagent injection amount is selected as 140ul. Other influencing factors (incubation temperature, incubation time, etc.) can also be designed and confirmed according to the same principle and method. After using these schemes, the detection of the marker reagent and the luminescent substrate reagent can accurately reflect the difference of the double sample needle adding amount, and is not affected by other factors, and can reliably calibrate the difference of the double sample needle.

[0167] In a fully automatic immune analyzer, the sample needle is responsible for completing the dispensing of the sample to be tested. For a fully automatic immune analyzer with two sample needles, the sample adding performance of the two sample needles needs to be consistent, and the difference in the sample adding performance of the double sample needles is the basis for the consistency control of the double sample needles. In the double sample needle system, the consistency of the double sample needles is controlled, that is, when the double sample needles dispense the same volume of liquid, the difference between the actual volumes of the two sample needles is as small as possible.

[0168] As an embodiment, the first marker reagent and the second marker reagent are both alkaline phosphatase solutions, but the alkaline phosphatase solution used by the first marker reagent and the alkaline phosphatase solution used by the second marker reagent are not the same, and the formulations and concentrations of the two are different, that is, a new alkaline phosphatase solution is designed for the sample loading calibration process. The present embodiment proposes a method of using alkaline phosphatase solution as a sample loading calibration reagent to measure and evaluate the consistency of the sample loading performance of the double-sample needle by reacting with an equal excess of luminescent substrate reagent to generate luminescence in a double-sample needle system. In the enzyme-free luminescence system, the final luminescence is the chemiluminescence generated by the alkaline phosphatase-labeled antigen or antibody and the magnetic bead-coated material catalyzing the luminescent substrate reagent, and the essence is that the alkaline phosphatase catalyzes the luminescent substrate reagent to generate luminescence; therefore, directly mixing and reacting the alkaline phosphatase with the excess luminescent substrate reagent, the final luminescence intensity is positively correlated with the amount of alkaline phosphatase added, and when a certain concentration of alkaline phosphatase solution is used, the final luminescence intensity is positively correlated with the volume of the alkaline phosphatase solution.

[0169] As an embodiment, the implementation of evaluating the volume difference of the liquid dispensed by the double-sample needle is as follows: in the immunoassay instrument, control the two sample needles to dispense the same volume of alkaline phosphatase solution into the excess and equal luminescent substrate reagent under the same working conditions, after a certain time of incubation (to ensure that the alkaline phosphatase solution and the luminescent substrate reagent are fully reacted), use the photometer of the immunoassay instrument to measure the light of the two reaction liquids, and obtain the luminescence intensity of the two reaction liquids obtained by reacting the alkaline phosphatase solution dispensed by the two sample needles with the luminescent substrate reagent. Then, combined with the quantitative relationship between the liquid volume dispensed by the sample needle and the luminescence value in the enzyme+substrate luminescence system, the difference in the actual liquid volume dispensed by the two sample needles is calculated. The quantitative relationship between the liquid volume dispensed by the sample needle and the luminescence value is the key to this method. In the enzyme+substrate reaction system, the sample loading transfer coefficient can be defined to reflect the quantitative relationship between the deviation of the liquid volume dispensed by the sample needle and the deviation of the final luminescence value: sample loading transfer coefficient = relative deviation of luminescence value / relative deviation of liquid volume dispensed by sample needle, wherein the relative deviation of the liquid volume dispensed by the sample needle is the difference in the liquid dispensing amount of the same volume of liquid dispensed by the two sample needles (i.e., the first sample needle 111 and the second sample needle 121), and the relative deviation of the luminescence value is the difference in the luminescence intensity of the two reaction liquids obtained by reacting the liquid dispensed by the two sample needles with the luminescent substrate reagent. The sample loading transfer coefficient is an inherent attribute of the quantitative relationship between the liquid volume dispensed by the sample needle and the luminescence value, and within a certain range of dispensing liquid volume, the sample loading transfer coefficient can be regarded as a constant. The relative deviation of the liquid volume dispensed by the sample needle can be calculated as follows: relative deviation of liquid volume dispensed by sample needle = relative deviation of luminescence value / sample loading transfer coefficient.

[0170] Since there are various sample volume specifications in the immunodetection scene of the sample, the sample dispensing amount deviation of the double-sample needle is different under different sample volume, and the sample delivery coefficient also has differences, so when quantifying the difference of the double-sample needle for sample dispensing amount calibration, the sample dispensing calibration process needs to be performed respectively in different calibration sample volume sections.

[0171] The sample dispensing calibration process of the double-sample needle sample dispensing system of the embodiment is executed by an immunization analyzer, the sample dispensing calibration sample for calibration enters the immunization analyzer through the sample inlet device, is distributed through the double-sample needle system of the sample dispensing device 100, and then is distributed with reagents through the reagent dispensing device 200, is incubated through the reaction device 900, is detected through the sample detection device 300, is treated with waste liquid, is treated with a cup throwing, and the like, so as to complete the whole test process. The detection result of the sample detection device 300 is input into the calibration compensation calculation module according to a specific calibration algorithm, a specific sample needle accuracy or a target dispensing amount is taken as a reference, the calibration correction amount of each needle is calculated, the calibration correction amount parameter is input into the parameter configuration module, and the sample dispensing correction amount configuration is performed for different sample dispensing volumes and different sample dispensing channels.

[0172] As an embodiment, the sample analyzer 10 pre-stores a first preset condition, and the first preset condition includes at least one of the following: a first preset time has been reached since the last execution of the sample addition calibration process; information on the completion of fault repair of the first sample dispensing component 110 and / or the second sample dispensing component 120 is obtained; information on the completion of loading of the first sample dispensing component 110 and / or the second sample dispensing component 120 is obtained; and a first preset time point of the first preset maintenance cycle is reached. The controller 400 is further configured to: execute the sample addition calibration process when the first preset condition is met. When the sample analyzer 10 pre-stores at least two of the above-mentioned first preset conditions, the sample addition calibration process is executed as long as any one of the first preset conditions is met. The first preset time has been reached since the last execution of the sample addition calibration process, specifically, after the sample addition calibration process is completed, the sample addition calibration process is executed every time the interval reaches the first preset time, for example, the sample addition calibration process is executed every six months, one year, three months, two months, or one month. Arriving at the first preset time point of the first preset maintenance cycle specifically refers to executing a sample addition calibration process once at a fixed time point, and is not associated with the interval length of the last execution of the sample addition calibration process. For example, the sample addition calibration process is executed once at 7:00 a.m. (or 7:30 or 8:00 a.m., etc.) on June 30 and December 31 of each year (or January 1, July 1 of each year, etc.). The first sample dispensing component 110 and / or the second sample dispensing component 120 completes fault repair, which mainly refers to the first sample dispensing component 110 and / or the second sample dispensing component 120 performing a sample addition calibration process once after at least some of its components fail and the repair is completed. The first sample dispensing assembly 110 and / or the second sample dispensing assembly 120 can be loaded after the sample analyzer 10 is initially installed for a specific application, or after at least some of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120 have been replaced after the sample analyzer 10 has been used for a period of time. In this embodiment, the sample loading and calibration process is not performed during the execution of a sample test project, and does not occupy the normal sample testing time of the sample analyzer 10. When the first preset condition is met, the sample loading and calibration process is automatically executed according to a pre-set procedure, making the execution of the sample loading and calibration process largely invisible to the operator and greatly reducing the interference of the sample loading and calibration process on the operator.

[0173] As an embodiment, the controller 400 is also configured to execute the following project calibration process: control one of the first sample dispensing component 110 and the second sample dispensing component 120 to draw the project calibrator from the second calibrator container and distribute it in the reaction container, control the reagent dispensing device 200 to draw the reagent from the reagent container and distribute it in the reaction container; control the sample detection device 300 to detect the calibration liquid made of at least the project calibrator and the reagent in the reaction container, and obtain the calibration data corresponding to the sample detection project based on the detection information fed back by the sample detection device 300. The project calibration process is mainly used to obtain the calibration data corresponding to the sample detection project, and the calibration data is used to calibrate the detection information obtained in the first detection process and the second detection process to obtain the detection result. The sample analyzer 10 can be used to execute multiple different detection projects, and each detection project corresponds to a calibration data. In this embodiment, since the first sample dispensing component 110 and the second sample dispensing component 120 perform the same detection project and share the same calibration data, the calibration data for each sample detection project can be performed once by only one of the first sample dispensing component 110 and the second sample dispensing component 120, without the need for both the first sample dispensing component 110 and the second sample dispensing component 120 to perform the calibration. There is also no need to calibrate the first sample dispensing component 110 and the second sample dispensing component 120 separately for each clinical project, which effectively reduces the calibration cost of the sample analyzer 10.

[0174] As an implementation, the controller 400 is further configured to perform a project calibration procedure of the first detection item, including: controlling the first sample dispensing assembly 110 to aspirate a project calibration sample from the second calibration sample container and dispense into a reaction container, controlling the reagent dispensing device 200 to aspirate a reagent from the reagent container and dispense into the reaction container; controlling the sample detection device 300 to detect a calibration solution made at least from the project calibration sample and the reagent in the reaction container, and obtaining first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device 300. The controller 400 is further configured to perform a second detection procedure of the first detection item, including: controlling the second sample dispensing assembly 120 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, and controlling the sample detection device 300 to detect a to-be-detected solution made at least from the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and the first calibration data corresponding to the first detection item. In the present embodiment, the second sample dispensing assembly 120 can use the calibration data obtained by the first sample dispensing assembly 110 performing the project calibration procedure when performing the second detection procedure, so that one sample detection item does not need to perform the project calibration procedure for both the first sample dispensing assembly 110 and the second sample dispensing assembly 120, but only needs to perform the project calibration procedure for one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120.

[0175] As an implementation, the sample analyzer 10 pre-stores a second preset condition, which includes at least one of the following: a second preset time length since the last execution of the item calibration process; a second preset time point of a second preset maintenance cycle; information of a newly loaded reagent container; information of a failed quality control detection result. The controller 400 is further configured to execute the item calibration process when the second preset condition is met. When the sample analyzer 10 pre-stores the above at least two second preset conditions, the item calibration process is executed as long as any one of the second preset conditions is met. The second preset time length since the last execution of the item calibration process specifically refers to that after the completion of one execution of the item calibration process, the item calibration process is executed every second preset time length. The second preset time point of the second preset maintenance cycle specifically refers to that the item calibration process is executed at a fixed time point, which is not associated with the interval time length of the last execution of the item calibration process. The information of the newly loaded reagent container can be obtained after the sample analyzer 10 completes the first installation in a specific application scenario, or after the sample analyzer 10 uses for a period of time and then replaces the reagent container. In this embodiment, the item calibration process is not executed during the execution of the sample detection item, which does not occupy the normal sample detection time of the sample analyzer 10, and is automatically executed according to the set program when the second preset condition is met, which is beneficial to make the operation personnel basically unaware of the execution of the item calibration process, and greatly reduces the interference of the item calibration process on the operation personnel.

[0176] As an implementation, the execution cycle of the item calibration process is 28 days, that is, the second preset maintenance cycle or the second preset time length is 28 days. When the reagent of a certain detection item is replaced, the item calibration process of the detection item is executed. When the quality control result of a certain detection item is wrong, the item calibration process of the detection item is executed.

[0177] As an implementation, the controller 400 is further configured to execute a quality control process, which can be executed once a day, for example, once before sample detection in the morning every day; or the quality control process can be executed twice a day, for example, once before sample detection in the morning and once before sample detection in the afternoon.

[0178] As an implementation, the calibration data (including but not limited to the first calibration data and the second calibration data) contains a plurality of groups of corresponding relationships between different known detection information and different calibration parameters. The calibration data can be a parameter of a linear function, or a calibration curve of a linear function, or a calibration database or table formed by a plurality of groups of known detection information and calibration parameters.

[0179] As an implementation, the sample analyzer 10 further comprises a sample management device 600 for placing sample containers to at least implement sample loading, and a sample conveying device 700 for conveying the sample containers output by the sample management device 600 to the sample loading position for sample dispensing by the sample dispensing device 100. The sample management device 600 can implement batch loading of sample containers, specifically, an operator or an operating robot can place sample containers loaded with samples to the sample management device 600, and the sample management device 600 is configured to store the sample containers and dispatch the sample containers loaded with samples to the sample conveying device 700. Of course, in specific applications, the sample analyzer 10 can also not be provided with the sample management device 600 and the sample conveying device 700, for example, as an alternative implementation, the sample containers loaded with samples are placed by an operator to the sample loading position for sample dispensing by the sample dispensing device 100.

[0180] As an implementation, the sample analyzer 10 further comprises a transfer device 104 for transferring reaction containers. The transfer device 104 is configured to perform at least one of the following transfer operations: transferring the sample loading completed reaction containers to the reaction device 900, transferring the incubation completed reaction containers from the reaction device 900 to the magnetic separation device 500; transferring the magnetic separation cleaning completed reaction containers from the magnetic separation device 500 to the detection position for detection; transferring the detection completed reaction containers to the cup throwing position for disposal and recycling.

[0181] As an implementation, the sample analyzer 10 further comprises a reaction container providing device 102 for providing reaction containers and a reaction container recycling device 103 for recycling reaction containers. The sample analyzer 10 further forms a recycling position, and the reaction container recycling device 103 is located below the recycling position. The transfer device 104 is at least configured to transfer the reaction containers from the detection position to the recycling position for release and recycling. In this implementation, the reaction containers are disposable containers, i.e., a reaction container is recycled after completing a detection item. Of course, in specific applications, the reaction containers can also be recycled containers, i.e., a reaction container can be cleaned and reused for other detection items after completing a test item in the sample analyzer 10.

[0182] The embodiment also provides a control method of the sample analyzer 10, including a first detection process and a second detection process. The first detection process includes: controlling the first sample dispensing assembly 110 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detection device 300 to detect a to-be-detected solution made of at least a sample dispensed by the first sample dispensing assembly 110 and a reagent dispensed by the reagent dispensing device 200, obtaining first detection data according to detection information fed back by the sample detection device 300, and obtaining a first detection result according to the first detection data and first calibration data. The second detection process includes: controlling the second sample dispensing assembly 120 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detection device 300 to detect a to-be-detected solution made of at least a sample dispensed by the second sample dispensing assembly 120 and a reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and second calibration data. When the detection item performed by the first detection process and the detection item performed by the second detection process are the same detection item, the first calibration data and the second calibration data are the same calibration data.

[0183] The specific principle and implementation manner of the control method of the sample analyzer 10 provided by the embodiment are similar to those described in the sample analyzer 10, and will not be described in detail here.

[0184] The embodiment also provides a computer readable storage medium, which stores a computer program. The computer program is executed by a processor (for example, the controller 400) to make the processor implement the steps of the control method of the sample analyzer 10. The computer readable storage medium can be an internal storage unit of the sample analyzer 10, for example, a hard disk or a memory of the sample analyzer 10. Alternatively, the computer readable storage medium can also be an external storage device of the sample analyzer 10, for example, a plug-in hard disk, a smart media card (SMC), a secure digital (SD) card, a flash card and the like.

[0185] In the embodiment, the sample dispensing device 100 is a double-sample needle system, that is, the sample needle of the sample dispensing device 100 is only the first sample needle 111 and the second sample needle 121, which can ensure efficiency and avoid the adverse phenomenon of excessive complexity of the structure and high cost of the sample dispensing device 100 due to too many sample needles. Of course, in specific applications, the sample dispensing device 100 is not limited to a double-sample needle system. For example, in addition to the first sample dispensing assembly 110 and the second sample dispensing assembly 120 described above, the sample dispensing device 100 can also include a third sample dispensing assembly, and the third sample dispensing assembly includes a third sample needle. The first sample needle 111, the second sample needle 121, and the third sample needle are three sample needles that can independently perform sample dispensing actions.

[0186] In the embodiment, when the multi-sample needle system is used to dispense samples, the multi-sample needle system can only perform a project calibration process once to obtain a calibration data corresponding to the detection project before the multi-sample needle system performs detection of the same detection project, and the multi-sample needle system can share the same calibration data (such as a calibration curve or a one-function parameter of the calibration curve) obtained by the project calibration process when performing the detection project of different samples. The accuracy of the multi-sample needle system is ensured by the whole machine sample calibration process, and the detection results of the project of the multi-sample needle system of the multiple sample dispensing systems are consistent. Only one calibration can be performed, and the same calibration data can be shared.

[0187] Embodiment Two:

[0188] The sample analyzer 10 provided in the embodiment is mainly different from the sample analyzer in Embodiment One in that the way of detecting the calibration sample dispensing amount in the sample calibration process is different, which is embodied in that: in Embodiment One, the calibration sample dispensing amount in the sample calibration process is detected by a chemiluminescence method; and in the embodiment, the calibration sample dispensing amount in the sample calibration process is detected by a weighing method.

[0189] Specifically, in the present embodiment, the dispensing amount detection device is a weighing device, and the control of the dispensing amount detection device to detect the first calibrant dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction vessel includes: controlling the weighing device to weigh the weight of the sample calibration liquid dispensed by the first sample dispensing assembly 110 into the reaction vessel, and obtaining the first calibrant dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction vessel according to the weight information fed back by the weighing device; the control of the dispensing amount detection device to detect the second calibrant dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction vessel includes: controlling the weighing device to weigh the weight of the sample calibration liquid dispensed by the second sample dispensing assembly 120 into the reaction vessel, and obtaining the second calibrant dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction vessel according to the weight information fed back by the weighing device. In a specific application, after the first sample dispensing assembly 110 dispenses the sample calibration liquid into the reaction vessel, the reaction vessel is placed on the weighing device for weighing, and the first calibrant dispensing amount can be obtained. After the second sample dispensing assembly 120 dispenses the sample calibration liquid into the reaction vessel, the reaction vessel is placed on the weighing device for weighing, and the second calibrant dispensing amount can be obtained. In the present embodiment, the first calibrant dispensing amount and the second calibrant dispensing amount in the sample calibration process are detected by weighing method. The sample calibration liquid can be water or diluent or other liquid, etc. The weighing device can be an external device of the sample analyzer 10, or an internal device of the sample analyzer 10. The weighing device can be an electronic scale or a balance, etc.

[0190] Except for the above differences, the other parts of the sample analyzer 10 provided by the present embodiment can refer to Embodiment One, which will not be described in detail here.

[0191] Embodiment Three:

[0192] The sample analyzer 10 provided by the present embodiment is mainly different from Embodiment One in the way of detecting the calibrant dispensing amount in the sample calibration process, which is embodied in: in Embodiment One, the calibrant dispensing amount in the sample calibration process is detected by chemiluminescence method; while in the present embodiment, the calibrant dispensing amount in the sample calibration process is detected by pigment light absorption detection method.

[0193] Specifically, in the embodiment, the dispensing amount detection device is a first optical detection device, and the sample calibration solution is a pigment solution. The method of controlling the first sample dispensing assembly 110 to suck the sample calibration solution and dispense it into the reaction container, and controlling the first optical detection device to detect the absorbance of the pigment solution dispensed into the reaction container by the first sample dispensing assembly 110 to obtain the first calibration solution dispensing amount dispensed into the reaction container by the first sample dispensing assembly 110, and the method of controlling the second sample dispensing assembly 120 to suck the sample calibration solution and dispense it into the reaction container, and controlling the first optical detection device to detect the absorbance of the pigment solution dispensed into the reaction container by the second sample dispensing assembly 120 to obtain the second calibration solution dispensing amount dispensed into the reaction container by the second sample dispensing assembly 120 are included. In the pigment absorbance method of the embodiment, the sample calibration solution is a pigment solution, and in the sample calibration process, the pigment solution does not need to be mixed or reacted with other solutions, and the absorbance is directly detected, that is, after the first sample dispensing assembly 110 dispenses the pigment solution into the reaction container, the first optical detection device directly detects the absorbance of the pigment solution in the reaction container to obtain the first calibration solution dispensing amount, and after the second sample dispensing assembly 120 dispenses the pigment solution into the reaction container, the first optical detection device directly detects the absorbance of the pigment solution in the reaction container to obtain the second calibration solution dispensing amount.

[0194] As an embodiment, the first optical detection device used by the dispensing amount detection device is the same detection device as the sample detection device 300, that is, the sample detection device 300 inside the immune analyzer is directly used as the dispensing amount detection device, so that an additional optical detection device does not need to be separately arranged to perform the sample calibration process. Of course, as an alternative embodiment, the first optical detection device used by the dispensing amount detection device and the sample detection device 300 can also be two different detection devices, for example, an optical detection device can be built-in or an optical detection device can be used as the first optical detection device in the sample analyzer 10.

[0195] In addition to the above differences, the other parts of the sample analyzer 10 provided by the embodiment can refer to Embodiment One, which will not be described in detail here.

[0196] Embodiment Four:

[0197] The sample analyzer 10 provided by the embodiment is mainly different from the sample analyzer of the embodiment three in that the pigment absorbance detection method used in the sample adding and calibration process is different, which is specifically reflected in that: in the sample adding and calibration process of the embodiment three, the pigment solution does not need to be mixed or reacted with other solutions, and the absorbance of the pigment solution directly added into the reaction container is detected; in the sample adding and calibration process of the embodiment, the pigment solution needs to be mixed with the diluent first, and then the absorbance of the mixed solution prepared by mixing the pigment solution and the diluent in the reaction container is detected.

[0198] Specifically, in the embodiment, the dispensing amount detection device is a first optical detection device, and the sample adding and calibration sample is a pigment solution; the control of the first sample dispensing assembly 110 to suck the sample adding and calibration sample and dispense it into the reaction container and the control of the dispensing amount detection device to detect the first calibration sample dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction container include: control of the first sample dispensing assembly 110 to suck the pigment solution and dispense it into the reaction container, control of the reagent dispensing device 200 to suck the diluent and dispense it into the reaction container, and control of the first optical detection device to detect the absorbance of the first mixed solution formed by at least the pigment solution dispensed by the first sample dispensing assembly 110 into the reaction container and the diluent dispensed by the reagent dispensing device 200 into the reaction container, to obtain the first calibration sample dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction container. The control of the second sample dispensing assembly 120 to suck the sample adding and calibration sample and dispense it into the reaction container and the control of the dispensing amount detection device to detect the second calibration sample dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction container include: control of the second sample dispensing assembly 120 to suck the pigment solution and dispense it into the reaction container, control of the reagent dispensing device 200 to suck the diluent and dispense it into the reaction container, and control of the first optical detection device to detect the absorbance of the second mixed solution formed by at least the pigment solution dispensed by the second sample dispensing assembly 120 into the reaction container and the diluent dispensed by the reagent dispensing device 200 into the reaction container, to obtain the second calibration sample dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction container. In the pigment absorbance method of the embodiment, the sample adding and calibration sample is a pigment solution, and in the sample adding and calibration process, the pigment solution needs to be mixed with the diluent first and then the absorbance is detected, that is: after the first sample dispensing assembly 110 dispenses the pigment solution into the reaction container, the diluent needs to be dispensed by the reagent dispensing device 200 first, and then the absorbance of the mixed solution in the reaction container is detected by the first optical detection device to obtain the first calibration sample dispensing amount; after the second sample dispensing assembly 120 dispenses the pigment solution into the reaction container, the diluent needs to be dispensed by the reagent dispensing device 200 first, and then the absorbance of the mixed solution in the reaction container is detected by the first optical detection device to obtain the second calibration sample dispensing amount. Of course, in specific applications, the diluent can not be dispensed by the reagent dispensing device 200, but can be dispensed by a special diluent dispensing device.

[0199] As an embodiment, the diluent is water (preferably purified water, deionized water), which is low in cost and easy to obtain. Of course, the setting mode of the diluent is not limited to this in specific applications. For example, as an alternative embodiment, the diluent can also be a sodium chloride solution or other liquids that can be used to dilute the pigment solution.

[0200] The setting mode of the first optical detection device can refer to Embodiment Three, which will not be described in detail here.

[0201] Except for the above differences, other parts of the sample analyzer 10 provided in this embodiment can refer to Embodiment One, which will not be described in detail here.

[0202] Embodiment Five:

[0203] The sample analyzer 10 provided in this embodiment is mainly different from Embodiment Four in that the sample calibration in the sample calibration process is different, which is embodied in that: in the sample calibration process of Embodiment Four, the sample calibration is a pigment solution, the diluent is added as a reagent, and then the absorbance of the mixed solution prepared by mixing the pigment solution and the diluent in the reaction container is detected; while in the sample calibration process of this embodiment, the sample calibration is a diluent, the pigment solution is added as a reagent, and then the absorbance of the mixed solution prepared by mixing the pigment solution and the diluent in the reaction container is detected.

[0204] Specifically, in the embodiment, the distribution amount detection device is a first optical detection device, and the sample calibration liquid is a diluent. The control of the first sample dispensing assembly 110 to suck the sample calibration liquid and distribute it in the reaction container and the control of the distribution amount detection device to detect the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly 110 include: control of the first sample dispensing assembly 110 to suck the diluent and distribute it in the reaction container, control of the reagent dispensing device 200 to suck the pigment solution and distribute it in the reaction container, and control of the first optical detection device to detect the absorbance of the third mixed liquid formed by mixing at least the diluent distributed in the reaction container by the first sample dispensing assembly 110 and the pigment solution distributed in the reaction container by the reagent dispensing device 200, to obtain the first calibration liquid distribution amount distributed in the reaction container by the first sample dispensing assembly 110. The control of the second sample dispensing assembly 120 to suck the sample calibration liquid and distribute it in the reaction container and the control of the distribution amount detection device to detect the second calibration liquid distribution amount distributed in the reaction container by the second sample dispensing assembly 120 include: control of the second sample dispensing assembly 120 to suck the diluent and distribute it in the reaction container, control of the reagent dispensing device 200 to suck the pigment solution and distribute it in the reaction container, and control of the first optical detection device to detect the absorbance of the fourth mixed liquid formed by mixing at least the diluent distributed in the reaction container by the second sample dispensing assembly 120 and the pigment solution distributed in the reaction container by the reagent dispensing device 200, to obtain the second calibration liquid distribution amount distributed in the reaction container by the second sample dispensing assembly 120. In the pigment absorbance method of the present embodiment, the sample calibration liquid is a diluent, and the pigment solution is added as an auxiliary liquid. In the sample calibration process, the absorbance of the mixed liquid of the diluent and the pigment solution is detected. Under the premise that the volume of the added pigment solution is fixed, the difference in the amount of the added diluent will directly affect the absorbance of the mixed liquid. When the first sample dispensing assembly 110 distributes the diluent in the reaction container, the reagent dispensing device 200 is first controlled to distribute the pigment solution, and then the first optical detection device is controlled to detect the absorbance of the mixed liquid in the reaction container, to obtain the first calibration liquid distribution amount. When the second sample dispensing assembly 120 distributes the diluent in the reaction container, the reagent dispensing device 200 is first controlled to distribute the pigment solution, and then the first optical detection device is controlled to detect the absorbance of the mixed liquid in the reaction container, to obtain the second calibration liquid distribution amount. Of course, in specific applications, the pigment solution can not be distributed by the reagent dispensing device 200, but can be distributed by a special pigment solution dispensing device.

[0205] As an embodiment, the diluent is water (preferably pure water or deionized water), which is low in cost and easy to obtain. Of course, in specific applications, the diluent can be set in other ways, for example, as an alternative embodiment, the diluent can also be a sodium chloride solution or other liquid that can be used to dilute the pigment solution.

[0206] The configuration of the first optical detection device can refer to the third embodiment and will not be described in detail here.

[0207] Except for the above differences, other parts of the sample analyzer 10 provided in this embodiment can refer to the first embodiment and will not be described in detail here.

[0208] Example 6:

[0209] Reference Figure 1 、 Figure 2 and Figure 5 As shown, the sample analyzer 10 provided in this embodiment is different from that in the first embodiment mainly in that the method of reducing the difference in accuracy of the sample amount distributed by the first sample dispensing component 110 and the sample amount distributed by the second sample dispensing component 120 is different, which is specifically reflected in: in the first embodiment, the sample distribution amount of the first sample dispensing component 110 and / or the second sample dispensing component 120 is corrected through the sample addition calibration process to ensure the consistency of the sample amount distributed by the first sample dispensing component 110 and the sample amount distributed by the second sample dispensing component 120; while in the present embodiment, the consistency of the sample amount distributed by the first sample dispensing component 110 and the sample amount distributed by the second sample dispensing component 120 is ensured by sharing at least some components.

[0210] Specifically, in this embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 share at least some components. In this embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 share at least some components, which can reduce the hardware differences between the first sample dispensing assembly 110 and the second sample dispensing assembly 120, thereby facilitating the reduction of differences in the sample amounts dispensed by the first sample dispensing assembly 110 and the second sample dispensing assembly 120. This can further meet the requirement for consistent sample amount dispensing across multiple sample needles without requiring a sample calibration process for the entire machine.

[0211] As an implementation form, the first sample dispensing assembly 110 further comprises a first suction driving component 112 configured to provide driving force for the first sample needle 111 to perform a suction action. The second sample dispensing assembly 120 further comprises a second suction driving component 122 configured to provide driving force for the second sample needle 121 to perform a suction action. The first suction driving component 112 and the second suction driving component 122 are the same suction driving component. Through analysis, in the multi-sample needle system, the main factor affecting the accuracy difference of the multi-sample needle system is the suction driving source, which accounts for more than 70%. In order to reduce the sample dispensing amount difference caused by the suction driving source, the present embodiment designs a sample dispensing device 100 with a single dispensing driving source and a multi-sample needle channel. The multi-sample needle system shares the dispensing driving source to dispense samples, which can effectively reduce the difference of the multi-sample needle channel. The design of the shared driving source can reduce more than 70% of the accuracy difference of the multi-sample needle system. After calculation, it can directly meet the precision requirements of sample dispensing and clinical detection projects, and does not need to be calibrated or allocated to different detection projects for different sample needles. It can greatly save the calibration cost and improve the detection efficiency.

[0212] As an implementation form, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can share other components in addition to the shared dispensing driving source, so as to share more components as much as possible to ensure the consistency of the sample dispensing amount of the two dispensing assemblies.

[0213] As an implementation form, the first sample dispensing assembly 110 further comprises a first cleaning driving component 113 configured to at least drive the cleaning liquid to flush the first sample needle 111. The second sample dispensing assembly 120 further comprises a second cleaning driving component 123 configured to at least drive the cleaning liquid to flush the second sample needle 121. The controller 400 is configured to: when the first suction driving component 112 is controlled to drive the first sample needle 111 to perform a sample dispensing action, the second cleaning driving component 123 is controlled to drive the cleaning liquid to flush the second sample needle 121; and / or when the second suction driving component 122 is controlled to drive the second sample needle 121 to perform a sample dispensing action, the first cleaning driving component 113 is controlled to drive the cleaning liquid to flush the first sample needle 111. In the present embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 alternately dispense samples and clean, that is, when one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 performs a sample dispensing action, the other performs a cleaning action, so as to reduce the influence of cleaning time on sample detection efficiency.

[0214] As an embodiment, the first sample dispensing component 110 also includes a first cleaning control valve 114 and a first liquid circuit 115, the first liquid circuit 115 is connected between the first cleaning drive component 113 and the first suction power component 112, the first cleaning drive component 113 is at least used to drive the cleaning liquid provided by the cleaning liquid supply device 20 to flow toward the first liquid circuit 115, and the first cleaning control valve 114 is provided on the first liquid circuit 115 to control the on-off of the first liquid circuit 115; the second sample dispensing component 120 also includes a second cleaning control valve 124 and a second liquid circuit 125, the second liquid circuit 125 is connected between the second cleaning drive component 123 and the first suction power component 112, the second cleaning drive component 123 is at least used to drive the cleaning liquid provided by the cleaning liquid supply device 20 to flow toward the second liquid circuit 125, and the second cleaning control valve 124 is provided on the second liquid circuit 125 to control the on-off of the second liquid circuit 125. The first cleaning drive component 113 and the second cleaning drive component 123 are the same component, the first cleaning control valve 114 and the second cleaning control valve 124 are the same component, and the first liquid path 115 and the second liquid path 125 are the same liquid path. In this embodiment, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 not only share a dispensing power source, but also a cleaning fluid power source and at least a portion of the cleaning control valves. This not only helps ensure consistency in sample dispensing amounts between the first sample dispensing assembly 110 and the second sample dispensing assembly 120, but also helps reduce the cost of the sample dispensing device 100. Of course, in specific applications, as an alternative implementation scheme, the first sample dispensing component 110 and the second sample dispensing component 120 may not share the cleaning liquid power source and part of the cleaning control valve, that is: in the alternative implementation scheme, the first cleaning drive component 113 and the second cleaning drive component 123 are two components that independently drive the flow of cleaning liquid, the first cleaning control valve 114 and the second cleaning control valve 124 are two components that independently control the on-off of the liquid path, and the first liquid path 115 and the second liquid path 125 are two liquid paths arranged in parallel.

[0215] As an implementation, the first sample dispensing assembly 110 further comprises a third washing control valve 116, a first sample adding control valve 117, a third liquid path 118 and a fourth liquid path 119, the third liquid path 118 is connected between the first washing driving part 113 and the first sample needle 111, the fourth liquid path 119 is connected between the first suction driving part 112 and the first sample needle 111, the third washing control valve 116 is arranged on the third liquid path 118 for controlling the opening and closing of the third liquid path 118, the first sample adding control valve 117 is arranged on the fourth liquid path 119 for controlling the opening and closing of the fourth liquid path 119. The second sample dispensing assembly 120 further comprises a fourth washing control valve 126, a second sample adding control valve 127, a fifth liquid path 128 and a sixth liquid path 129, the fifth liquid path 128 is connected between the second washing driving part 123 and the second sample needle 121, the sixth liquid path 129 is connected between the first suction driving part 112 and the second sample needle 121, the fourth washing control valve 126 is arranged on the fifth liquid path 128 for controlling the opening and closing of the fifth liquid path 128, the second sample adding control valve 127 is arranged on the sixth liquid path 129 for controlling the opening and closing of the sixth liquid path 129. The controller 400 is configured to: when it is required to control the first sample dispensing assembly 110 to perform a sample dispensing action, control the first washing control valve 114, the second washing control valve 124, the third washing control valve 116 and the second sample adding control valve 127 to be closed, control the first sample adding control valve 117 and the fourth washing control valve 126 to be opened, control the first suction driving part 112 to be started to drive the first sample needle 111 to perform the sample dispensing action, control the second washing driving part 123 to be started to drive the washing liquid to flush the second sample needle 121; when it is required to control the second sample dispensing assembly 120 to perform a sample dispensing action, control the first washing control valve 114, the second washing control valve 124, the fourth washing control valve 126 and the first sample adding control valve 117 to be closed, control the second sample adding control valve 127 and the third washing control valve 116 to be opened, control the second suction driving part 122 to be started to drive the second sample needle 121 to perform the sample dispensing action, control the first washing driving part 113 to be started to drive the washing liquid to flush the first sample needle 111. With the present implementation, the design requirement that one sample needle performs a sample dispensing action and the other sample needle performs a washing action can be met.

[0216] Except for the differences described above, other parts of the sample analyzer 10 provided by the present embodiment can refer to Embodiments One to Five, which will not be described in detail here.

[0217] Embodiment Seven:

[0218] The sample analyzer 10 provided by the embodiment is mainly different from the first embodiment in the way of reducing the accuracy difference of the sample dispensing amount of the first sample dispensing assembly 110 and the sample dispensing amount of the second sample dispensing assembly 120, which is embodied in that: in the first embodiment, the sample dispensing amount of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120 is corrected through the whole machine sample adding calibration process to ensure the consistency of the sample dispensing amount of the first sample dispensing assembly 110 and the sample dispensing amount of the second sample dispensing assembly 120; while in the embodiment, the sample dispensing amount of the first sample dispensing assembly 110 and at least part of the components of the second sample dispensing assembly 120 are calibrated in advance to obtain sample adding correction parameters, and the sample adding correction parameters are associated with the corresponding components. When the components associated with the sample adding correction parameters are applied to the sample analyzer 10, the sample adding correction parameters can be directly obtained without calibration in the sample analyzer 10.

[0219] Specifically, in the embodiment, at least part of the components of at least one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are associated with sample adding correction parameters. The sample analyzer 10 further comprises a first information acquisition component and a controller 400, the first information acquisition component is used to acquire the sample adding compensation parameters of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120. The controller 400 is further configured to: acquire the sample adding correction parameters of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120 according to the information fed back by the first information acquisition component; and correct the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the sample adding correction parameters of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120. In the embodiment, at least part of the components of at least one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are calibrated in advance to obtain sample adding correction parameters, and the sample adding correction parameters are associated with the corresponding components. In this way, when the components are loaded into the sample analyzer, the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action can be corrected by directly acquiring the sample adding correction parameters of the components, so as to meet the design requirements of the target sample dispensing amount, that is, the calibration of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 is performed in advance by components, rather than by the whole machine of the sample analyzer 10. In this way, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are exempted from performing the sample adding calibration process again after being loaded into the machine, and do not need to be calibrated separately for different clinical detection items or to dispense different detection items for different samples, which can save calibration cost and improve the detection efficiency of the sample analyzer 10.

[0220] As an implementation, at least part of components of at least one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 is configured with an identification code, and the identification code is associated with the sample dispensing correction parameter of the component; the first information acquisition component acquires the sample dispensing correction parameter of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120 by identifying the identification code. The identification code includes at least one of a bar code, a two-dimensional code, and a radio frequency code. In this embodiment, the sample dispensing correction parameter of at least part of components of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 is acquired by scanning the code, so as to correct the sample dispensing amount of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120, thereby realizing rapid calibration of the first sample dispensing assembly 110 and / or the second sample dispensing assembly 120, and the method of identifying the sample dispensing correction parameter greatly simplifies the complexity of manual operation. When the dispensing assembly and the dispensing component are replaced, the sample dispensing correction parameter can be directly configured by scanning the code, thereby greatly increasing the replaceability and calibration convenience of the assembly and the component.

[0221] As an implementation, a label paper is pasted on at least part of components of at least one of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, and the label paper is provided with an identification code. The identification code is fixed on the component by pasting, and the operation is convenient.

[0222] As an implementation, the first sample needle 111 is configured with a first identification code, and the first identification code is associated with the sample dispensing correction parameter of the first sample needle 111. The first information acquisition component is used to identify the first identification code; the controller 400 is further configured to acquire the sample dispensing correction parameter of the first sample needle 111 according to the information fed back by the first information acquisition component identifying the first identification code; and correct the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action according to at least the sample dispensing correction parameter of the first sample needle 111, so that the deviation of the sample dispensing accuracy of the first sample dispensing assembly 110 and the sample dispensing accuracy of the second sample dispensing assembly 120 is less than or equal to the first preset value. In this embodiment, the first sample needle 111 is provided with the first identification code, and when the first sample needle 111 is loaded on the sample analyzer 10, the sample dispensing correction parameter of the first sample needle 111 can be obtained by scanning the code, and the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action is corrected according to the sample dispensing correction parameter of the first sample needle 111, without the need to perform the sample dispensing calibration process on the whole machine.

[0223] As an implementation, the second sample needle 121 is configured with a second identification code, and the second identification code is associated with the sample loading correction parameter of the second sample needle 121; the sample analyzer 10 further comprises a first information acquisition component, which is used to identify the second identification code; the controller 400 is further configured to: acquire the sample loading correction parameter of the second sample needle 121 according to the information fed back by the first information acquisition component identifying the second identification code; and correct the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to at least the sample loading correction parameter of the second sample needle 121, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly 110 and the sample dispensing accuracy of the second sample dispensing assembly 120 is less than or equal to the first preset value. In the embodiment, the second sample needle 121 is provided with the second identification code, and when the second sample needle 121 is loaded on the sample analyzer 10, the sample loading correction parameter of the second sample needle 121 can be obtained by scanning the code, and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is corrected according to the sample loading correction parameter of the second sample needle 121, without the need to perform the sample loading calibration process on the whole machine.

[0224] As an implementation, the controller 400 is further configured to: before controlling the first sample needle 111 to perform the first sample dispensing action on the sample analyzer 10, acquire the sample loading correction parameter of the first sample needle 111 according to the information fed back by the first information acquisition component identifying the first identification code. Before the first sample needle 111 performs the first sample dispensing action on the sample analyzer 10, it can be that the sample analyzer 10 is used for the first time after installation and before the first sample needle 111 performs the first sample dispensing action, or it can be that the sample analyzer 10 is used for a period of time and the first sample needle 111 is replaced, and before the replaced first sample needle 111 performs the first sample dispensing action. In specific applications, when the first sample needle 111 fails or is damaged, a calibrated sample needle with an identification code can be re-issued as a new first sample needle 111 to replace the old first sample needle 111 on the sample analyzer 10. After the first sample dispensing assembly 110 is re-scanned and the sample dispensing parameters are configured, the multiple sample needles can be used to jointly dispense samples.

[0225] As an implementation form, the controller 400 is further configured to: before the second sample needle 121 performs the first sample dispensing action on the sample analyzer 10, acquire the sample adding correction parameter of the second sample needle 121 according to the information fed back by the identification of the second identification code by the first information acquisition component. Before the second sample needle 121 performs the first sample dispensing action on the sample analyzer 10, it can be that the sample analyzer 10 is used for the first time after installation and before the second sample needle 121 performs the first sample dispensing action, or it can be that the sample analyzer 10 is used for a period of time and the second sample needle 121 is replaced, and before the replaced second sample needle 121 performs the first sample dispensing action. In specific applications, when the second sample needle 121 fails or is damaged, a calibrated sample needle with an identification code can be re-issued as a new second sample needle 121 to replace the old second sample needle 121 on the sample analyzer 10. After the sample dispensing parameters of the second sample dispensing assembly 120 are configured again after the first time after installation, the multi-sample needle joint dispensing sample can continue to be used.

[0226] As an implementation form, the first sample dispensing assembly 110 further comprises a first suction and injection power component 112 for providing driving force for the first sample needle 111 to perform the suction and injection action. The first suction and injection power component 112 is provided with a third identification code, and the third identification code is associated with the sample adding correction parameter of the first suction and injection power component 112. The sample analyzer 10 further comprises a first information acquisition component for identifying the third identification code. The controller 400 is further configured to: acquire the sample adding correction parameter of the first suction and injection power component 112 according to the information fed back by the identification of the third identification code by the first information acquisition component; and correct the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action according to the sample adding correction parameter of the first suction and injection power component 112, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly 110 and the sample dispensing accuracy of the second sample dispensing assembly 120 is less than or equal to the first preset value. In this embodiment, the first suction and injection power component 112 is provided with a third identification code. When the first suction and injection power component 112 is loaded on the sample analyzer 10, the sample adding correction parameter of the first suction and injection power component 112 can be obtained by scanning the code, and the sample dispensing amount of the first sample dispensing assembly 110 in the sample dispensing action is corrected according to the sample adding correction parameter of the first suction and injection power component 112, without the need to perform the sample adding calibration process on the whole machine.

[0227] As an implementation form, the second sample dispensing assembly 120 further comprises a second suction and injection power component 122 configured to provide driving force for the suction and injection action of the second sample needle 121; the second suction and injection power component 122 is provided with a fourth identification code, and the fourth identification code is associated with the sample adding correction parameter of the second suction and injection power component 122; the sample analyzer 10 further comprises a first information acquisition component configured to identify the fourth identification code; and the controller 400 is further configured to: acquire the sample adding correction parameter of the second suction and injection power component 122 according to the information fed back by the first information acquisition component when identifying the fourth identification code; and correct the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action according to the sample adding correction parameter of the second suction and injection power component 122, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly 110 and the sample dispensing accuracy of the second sample dispensing assembly 120 is less than or equal to the first preset value. In the implementation form, the second suction and injection power component 122 is provided with the fourth identification code, and when the second suction and injection power component 122 is loaded on the sample analyzer 10, the sample adding correction parameter of the second suction and injection power component 122 can be obtained by scanning the code, and the sample dispensing amount of the second sample dispensing assembly 120 in the sample dispensing action is corrected according to the sample adding correction parameter of the second suction and injection power component 122, so that the sample adding calibration process does not need to be performed on the whole machine.

[0228] As an implementation form, the controller 400 is further configured to: acquire the sample adding correction parameter of the first suction and injection power component 112 according to the information fed back by the first information acquisition component when identifying the third identification code before controlling the first suction and injection power component 112 to perform the first sample dispensing action on the sample analyzer 10. Before the first suction and injection power component 112 performs the first sample dispensing action on the sample analyzer 10, the first suction and injection power component 112 can be replaced after the sample analyzer 10 is used for a period of time, or the first suction and injection power component 112 can be replaced before the first suction and injection power component 112 performs the first sample dispensing action after the sample analyzer 10 is used for a period of time. In specific applications, when the first suction and injection power component 112 fails or is damaged, a calibrated suction and injection power component with an identification code can be obtained as a new first suction and injection power component 112 to replace the old first suction and injection power component 112 on the sample analyzer 10, and after the new first suction and injection power component 112 is loaded and the sample dispensing parameters of the first sample dispensing assembly 110 are configured by scanning the code, the multiple-sample-needle joint sample dispensing can be continued.

[0229] As an implementation, the controller 400 is further configured to: before the second pipetting power component 122 performs the first sample dispensing action on the sample analyzer 10, acquire the sample dispensing correction parameter of the second pipetting power component 122 according to the information fed back by the fourth identification code identified by the first information acquisition component. Before the second pipetting power component 122 performs the first sample dispensing action on the sample analyzer 10, it can be that the sample analyzer 10 is first installed in the application scenario and before the second pipetting power component 122 performs the first sample dispensing action, or it can be that the sample analyzer 10 is used for a period of time and the second pipetting power component 122 is replaced, and before the replaced second pipetting power component 122 performs the first sample dispensing action. In specific applications, when the second pipetting power component 122 fails or is damaged, a calibrated pipetting power component with an identification code can be re-issued as a new second pipetting power component 122 to replace the old second pipetting power component 122 on the sample analyzer 10. After the sample dispensing parameter of the second sample dispensing assembly 120 is re-scanned and configured, the multi-sample needle combined sample dispensing can continue to be used.

[0230] After analysis, in the multi-sample needle system, the main factors affecting the accuracy difference of the multi-sample needle system are the pipetting power component and the sample needle, among which the pipetting power component accounts for more than 70%, and the sample needle accounts for more than 25%. In order to reduce the sample dispensing amount difference caused by the difference between the pipetting power component and the sample needle, the embodiment designs a method of calibrating the pipetting power component and the sample needle so that they can reach the target sample dispensing amount, and the sample dispensing parameter can be scanned and configured, so that the first sample dispensing assembly 110 and the second sample dispensing assembly 120 and their components are installed without performing the sample dispensing calibration process again. The method of calibrating the pipetting power component and the sample needle can reduce the accuracy difference of the multi-sample needle system by more than 95%, and after calculation, it can directly meet the precision requirements of sample dispensing and clinical detection projects, and does not need to be calibrated separately or assigned different detection projects for different sample needles. It can save calibration cost and improve the detection efficiency of the sample analyzer 10. Of course, in specific applications, it is not limited to calibrating the identification code of the pipetting power component and the sample needle in advance, but also can calibrate the identification code of other components of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 in advance.

[0231] As an implementation, the method for pre-calibrating the first sample dispensing assembly 110 and the second sample dispensing assembly 120 and their components, so as to eliminate the sample needle calibration after the machine is started, comprises the following steps: (1) preparing the components and parts of the multi-sample needle system, such as the suction and injection power components, sample needles, etc.; (2) applying the precision measurement platform and the corresponding algorithm to the suction and injection power components, so that each suction and injection power component is calibrated to the same target sample dispensing amount, the sample calibration parameters related to each suction and injection power component are recorded, the sample calibration parameters are identified and coded, and are pasted on the corresponding suction and injection power component; (3) applying the structure measurement platform and the corresponding algorithm to the sample needles, so that each sample needle is calibrated to the same target sample dispensing amount, the sample calibration parameters related to each sample needle are recorded, the sample calibration parameters are identified and coded, and are pasted on the corresponding sample needle; (4) after the suction and injection power components and the sample needles are assembled on the machine, the corresponding sample calibration parameters are configured by scanning the code, and after the configuration is successful, the sample dispensing amount accuracy difference of the multi-sample needle system can be basically eliminated, and the multi-sample needle joint detection can be directly performed, so as to eliminate the sample calibration process after the machine is started. The method for calibrating the suction and injection power components and the sample needles can reduce the accuracy difference of more than 95% of the multi-sample needle system, and can directly meet the precision requirements of sample dispensing and clinical detection items.

[0232] In the embodiment, the sample calibration parameters of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are identified and coded, so that the parameters can be directly configured by scanning the code. When the components or parts of the multi-sample needle system fail or are damaged, especially when the dispensing power components and / or the sample needles fail or are damaged, the calibrated dispensing power components and / or sample needles with the identification code can be re-obtained, and after the sample dispensing parameters are re-configured by scanning the code after the machine is started, the multi-sample needle joint can continue to perform the sample dispensing action.

[0233] In the embodiment, the dispensing power components and the sample needles are calibrated separately, which directly ensures the consistency of the sample dispensing amount from the root of the sample dispensing amount difference of the multi-sample needle system, and does not need to separately perform the sample calibration process or the clinical item calibration operation, so as to directly meet the precision requirements of the clinical item detection, and the method for identifying and coding the sample calibration parameters greatly simplifies the complexity of the human operation. When the sample dispensing assembly and the components are replaced, the sample calibration parameters can be directly configured by scanning the code, which greatly increases the replaceability and the replacement convenience of the multi-sample needle system.

[0234] In addition to the above differences, the other parts of the sample analyzer 10 provided by the embodiment can refer to the first to sixth embodiments, and will not be described in detail here.

[0235] Embodiment Eight:

[0236] The sample analyzer 10 provided by the embodiment is mainly different from the first embodiment in the setting mode of the reagent system, the reaction system and the detection system, which is embodied in that in the first embodiment, the first detection process and the second detection process share the reagent system, the reaction system and the detection system; while in the embodiment, the first detection process and the second detection process do not share at least one of the reagent system, the reaction system and the detection system.

[0237] Specifically, in the embodiment, the at least one device used in the first detection process and the second detection process is a device whose at least part of components can work independently of each other, which is the reagent dispensing device 200, the reaction device 900 and the sample detection device 300. In the embodiment, in the first detection process and the second detection process, in addition to the sample system, at least part of components of the reagent system, the reaction system and the detection system are not shared, as long as the final detection result deviation is within an acceptable range.

[0238] As an implementation, the at least one device used in the first detection process and the second detection process is a device whose at least part of components can work independently of each other and has a calibration parameter for calibration, which is the reagent dispensing device 200, the reaction device 900 and the sample detection device 300. In the embodiment, for the inconsistent components in the reagent system, the reaction system and the detection system, a calibration correction method (for example, similar to the parameter identification code correction method of part of the components in the sample system in the seventh embodiment) is adopted to make the performance of the inconsistent components in the reagent system, the reaction system and the detection system consistent. In the embodiment, the sample system and the reagent system, the reaction system and the detection system are respectively corrected to meet the consistency requirement; of course, in specific applications, as an alternative embodiment, the sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can be inconsistent, but the detection result consistency can be met by correction of at least one of the reagent system, the reaction system, the detection system, for example, by synchronous correction of the reagent system and / or the reaction system to correct the detection result deviation caused by the inconsistent sample dispensing amount, so as to ensure the consistency of the detection result.

[0239] As an implementation, the reagent dispensing device 200 comprises a second reagent dispensing assembly and a third reagent dispensing assembly, the second reagent dispensing assembly comprises a second reagent needle and a fifth suction power component, the fifth suction power component is used to drive the second reagent needle to suck reagent from the reagent container and drive the second reagent needle to dispense at least part of the sucked reagent into the reaction container, the third reagent dispensing assembly comprises a third reagent needle and a sixth suction power component, the sixth suction power component is used to drive the third reagent needle to suck reagent from the reagent container and drive the third reagent needle to dispense at least part of the sucked reagent into the reaction container; the reaction device 900 comprises a second reaction disc and a third reaction disc, the second reaction disc and the third reaction disc are respectively used to carry the reaction container for incubating the sample and the reagent. The detection device comprises a second light receiving component and a third light receiving component, the second light receiving component is used to perform optical detection on the to-be-detected liquid in the reaction container after incubation by the second reaction disc, and the third light receiving component is used to perform optical detection on the to-be-detected liquid in the reaction container after incubation by the third reaction disc. The controller 400 is further configured to: correct the reagent dispensing amount of the second reagent dispensing assembly and / or the reagent dispensing amount of the third reagent dispensing assembly, so that the deviation of the reagent dispensing accuracy of the second reagent dispensing assembly and the reagent dispensing accuracy of the third reagent dispensing assembly is less than or equal to a second preset value; correct the incubation condition of the second reaction disc and / or the incubation condition of the third reaction disc, so that the deviation of the incubation accuracy of the second reaction disc and the incubation accuracy of the third reaction disc is less than or equal to a third preset value; correct the light measurement accuracy of the second light receiving component and / or the light measurement accuracy of the third light receiving component, so that the deviation of the light measurement accuracy of the second light receiving component and the light measurement accuracy of the third light receiving component is less than or equal to a fourth preset value. In this implementation, the second reagent dispensing assembly and the third reagent dispensing assembly can work in parallel, the second reaction disc and the third reaction disc can work in parallel, and the second light receiving component and the third light receiving component can work in parallel.

[0240] As an implementation, at least one of the following devices used in the first detection process and the second detection process is two devices that can work independently at least in part and have calibration parameters for calibration: the magnetic separation device 500 and the substrate dispensing device 101, that is, the first detection process and the second detection process can also not share the magnetic separation system and / or the substrate dispensing system.

[0241] As an implementation, for inconsistent components in the magnetic separation system and the substrate dispensing system, a calibration correction method (for example, similar to the parameter identification coding method of part of the components in the sample system in Example Seven) can be used to make the performance of the non-shared parts of the magnetic separation system and the substrate dispensing system consistent.

[0242] In addition to the above differences, other parts of the sample analyzer 10 provided by the present embodiment can refer to Examples One to Seven, which will not be described in detail here.

[0243] Embodiment Nine

[0244] The sample analyzer 10 provided by the embodiment mainly differs from the embodiment one in the protection emphasis, specifically embodied as: in the embodiment one, the emphasis is on protecting that the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can share the calibration data when used for detecting the same detection item of different samples; while in the embodiment, the emphasis is on protecting that the calibration data obtained by the first sample dispensing assembly 110 in the item calibration process can be used in the detection process of the second sample dispensing assembly 120.

[0245] Specifically, the sample analyzer 10 provided by the embodiment comprises a sample dispensing device 100, a reagent dispensing device 200, a sample detection device 300 and a controller 400. The sample dispensing device 100 comprises a first sample dispensing assembly 110 and a second sample dispensing assembly 120, and the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are respectively used to perform a sample dispensing action of sucking a sample from a sample container and dispensing at least part of the sample into a reaction container. The first sample dispensing assembly 110 comprises a first sample needle 111, and the second sample dispensing assembly 120 comprises a second sample needle 121, and the first sample needle 111 and the second sample needle 121 are two sample needles capable of independently performing the sample dispensing action. The reagent dispensing device 200 is used to perform a reagent dispensing action of sucking a reagent from a reagent container and dispensing at least part of the reagent into the reaction container. The sample detection device 300 is used to detect a to-be-tested liquid made of at least the sample dispensed by the sample dispensing device 100 and the reagent dispensed by the reagent dispensing device 200. The controller 400 is configured to perform a project calibration process of a first detection item as follows: controlling the first sample dispensing assembly 110 to suck a project calibration sample from a second calibration sample container and dispense it into a reaction container, and controlling the reagent dispensing device 200 to suck a reagent from a reagent container and dispense it into the reaction container; controlling the sample detection device 300 to detect a calibration liquid made of at least the project calibration sample and the reagent in the reaction container, and obtaining first calibration data corresponding to the first detection item according to detection information fed back by the sample detection device 300; and the controller 400 is further configured to perform a second detection process of the first detection item as follows: controlling the second sample dispensing assembly 120 to perform the sample dispensing action, controlling the reagent dispensing device 200 to perform the reagent dispensing action, and controlling the sample detection device 300 to detect the to-be-tested liquid made of at least the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and the first calibration data corresponding to the first detection item. In the embodiment, since the second sample dispensing assembly 120 can directly use the calibration data obtained by the first sample dispensing assembly 110 performing the project calibration process when performing the sample detection process, for the same detection item, the project calibration process does not need to be performed on the first sample dispensing assembly 110 and the second sample dispensing assembly 120 respectively, which is beneficial to improving the calibration efficiency and reducing the calibration cost.

[0246] As an embodiment for ensuring consistency of sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, the sample analyzer 10 further comprises a dispensing amount detection device, and the controller 400 is further configured to perform a sample addition calibration process as follows: controlling the first sample dispensing assembly 110 to aspirate a sample addition calibration product and dispense it into a reaction vessel, controlling the dispensing amount detection device to detect the first calibration product dispensing amount dispensed by the first sample dispensing assembly 110 into the reaction vessel; controlling the second sample dispensing assembly 120 to aspirate a sample addition calibration product and dispense it into a reaction vessel, controlling the dispensing amount detection device to detect the second calibration product dispensing amount dispensed by the second sample dispensing assembly 120 into the reaction vessel; and correcting the sample dispensing amount of the first sample dispensing assembly 110 in performing a sample dispensing action and / or the sample dispensing amount of the second sample dispensing assembly 120 in performing a sample dispensing action according to the first calibration product dispensing amount and the second calibration product dispensing amount, so that the deviation between the sample dispensing accuracy of the first sample dispensing assembly 110 and the sample dispensing accuracy of the second sample dispensing assembly 120 is less than or equal to a first preset value. This embodiment adopts a whole machine to perform a sample addition calibration process, thereby reducing the difference in sample dispensing amount accuracy between the first sample dispensing assembly 110 and the second sample dispensing assembly 120.

[0247] As another embodiment for ensuring consistency of sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, the first sample dispensing assembly 110 further comprises a first aspiration power component 112 for providing driving force for the first sample needle 111 to perform an aspiration action, and the second sample dispensing assembly 120 further comprises a second aspiration power component 122 for providing driving force for the second sample needle 121 to perform an aspiration action; the first aspiration power component 112 and the second aspiration power component 122 are the same aspiration power component. This embodiment adopts a common sample dispensing power source, thereby reducing the difference in sample dispensing amount accuracy between the first sample dispensing assembly 110 and the second sample dispensing assembly 120.

[0248] As another implementation to ensure consistency of sample dispensing amount of the first sample dispensing assembly 110 and the second sample dispensing assembly 120, the first sample needle 111 is configured with a first identification code, the first identification code is associated with sample loading correction parameters of the first sample needle 111; the sample analyzer 10 further comprises a first information acquisition component, the first information acquisition component is used to identify the first identification code; the controller 400 is further configured to: acquire the sample loading correction parameters of the first sample needle 111 according to the information fed back by the first information acquisition component identifying the first identification code; and correct the sample dispensing amount of the first sample dispensing assembly 110 in the execution of the sample dispensing action according to at least the sample loading correction parameters of the first sample needle 111, so that the deviation of the sample dispensing precision of the first sample dispensing assembly 110 and the sample dispensing precision of the second sample dispensing assembly 120 is less than or equal to the first preset value; and / or, the second sample needle 121 is configured with a second identification code, the second identification code is associated with sample loading correction parameters of the second sample needle 121; the sample analyzer 10 further comprises a first information acquisition component, the first information acquisition component is used to identify the second identification code; the controller 400 is further configured to: acquire the sample loading correction parameters of the second sample needle 121 according to the information fed back by the first information acquisition component identifying the second identification code; and correct the sample dispensing amount of the second sample dispensing assembly 120 in the execution of the sample dispensing action according to at least the sample loading correction parameters of the second sample needle 121, so that the deviation of the sample dispensing precision of the first sample dispensing assembly 110 and the sample dispensing precision of the second sample dispensing assembly 120 is less than or equal to the first preset value. The implementation adopts the identification code of the correction parameters to reduce the difference in sample dispensing amount accuracy of the first sample dispensing assembly 110 and the second sample dispensing assembly 120.

[0249] In addition to the above, other parts of the sample analyzer 10 provided by the present embodiment can refer to Embodiments 1-8, which will not be described in detail here.

[0250] Embodiment Ten:

[0251] The sample analyzer 10 provided by the present embodiment is mainly different from Embodiment One in that the condition for sharing calibration data by the first detection process and the second detection process is different, which is embodied in that: in Embodiment One, as long as the first detection process and the second detection process are used to measure the same detection item of different samples, the calibration data is shared; while in the present embodiment, only when the first detection process is in the first working mode and the detection item executed by the first detection process and the detection item executed by the second detection process are the same detection item, the first detection process and the second detection process share the calibration data; while in the second working mode, and when the detection item executed by the first detection process and the detection item executed by the second detection process are the same detection item, the first detection process and the second detection process use different calibration data.

[0252] Specifically, the sample analyzer 10 provided by the embodiment comprises a sample dispensing device 100, a reagent dispensing device 200, a sample detection device 300 and a controller 400. The sample dispensing device 100 comprises a first sample dispensing assembly 110 and a second sample dispensing assembly 120, and the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are respectively used to perform the following sample dispensing action: sucking a sample from a sample container and dispensing at least part of the sucked sample into a reaction container; wherein the first sample dispensing assembly 110 comprises a first sample needle 111, and the second sample dispensing assembly 120 comprises a second sample needle 121, and the first sample needle 111 and the second sample needle 121 are two sample needles capable of independently performing the sample dispensing action. The reagent dispensing device 200 is used to perform the following reagent dispensing action: sucking a reagent from a reagent container and dispensing at least part of the sucked reagent into a reaction container. The sample detection device 300 is used to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device 100 and a reagent dispensed by the reagent dispensing device 200. The controller 400 is configured to perform the following first detection process: controlling the first sample dispensing assembly 110 to perform the sample dispensing action, controlling the reagent dispensing device 200 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-tested liquid made of at least the sample dispensed by the first sample dispensing assembly 110 and the reagent dispensed by the reagent dispensing device 200, obtaining first detection data according to detection information fed back by the sample detection device 300, and obtaining a first detection result according to the first detection data and first calibration data. The controller 400 is further configured to perform the following second detection process: controlling the second sample dispensing assembly 120 to perform the sample dispensing action, controlling the reagent dispensing device 200 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-tested liquid made of at least the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and second calibration data. Wherein, the sample analyzer 10 is configured with a first working mode and a second working mode; in the first working mode, the controller 400 is configured to: when the detection items performed by the first detection process and the detection items performed by the second detection process are the same detection items, set the first calibration data and the second calibration data to use the same calibration data; in the second working mode, the controller 400 is configured to: when the detection items performed by the first detection process and the detection items performed by the second detection process are the same detection items, set the first calibration data and the second calibration data to use two different calibration data respectively.In the embodiment, the sample analyzer 10 is configured with two working modes. In one working mode, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 can share the calibration data when used for detecting the same detection item. In another working mode, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 cannot share the calibration data even when used for detecting the same detection item. In this way, the user can select different working modes according to actual needs to meet the needs of different application occasions and different users.

[0253] As an implementation, the controller 400 is configured to perform the following item calibration process of the first detection item: control the first sample dispensing assembly 110 to suck the item calibration sample from the second calibration sample container and dispense it into the reaction container, control the reagent dispensing device 200 to suck the reagent from the reagent container and dispense it into the reaction container; control the sample detection device 300 to detect the calibration solution made of at least the item calibration sample and the reagent in the reaction container, and obtain the first calibration data corresponding to the first detection item according to the detection information fed back by the sample detection device 300. In the first working mode, the controller 400 is configured to perform the following second detection process of the first detection item: control the second sample dispensing assembly 120 to perform the sample dispensing action, control the reagent dispensing device 200 to perform the reagent dispensing action, control the sample detection device 300 to detect the to-be-tested solution made of at least the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtain the second detection data according to the detection information fed back by the sample detection device 300, and obtain the second detection result according to the second detection data and the first calibration data corresponding to the first detection item. In the embodiment, for the same detection item, the item calibration process can be performed on the first sample dispensing assembly 110 and the second sample dispensing assembly 120 respectively, and the second sample dispensing assembly 120 can directly use the calibration data obtained by the first sample dispensing assembly 110 performing the item calibration process when performing the sample detection process. This is conducive to improving the calibration efficiency and reducing the calibration cost.

[0254] In addition to the above, other parts of the sample analyzer 10 provided by the embodiment can refer to Embodiments 1 to 9, which will not be described in detail here.

[0255] Embodiment Eleven:

[0256] The sample analyzer 10 provided by the embodiment differs from the first embodiment mainly in that the condition for the first detection process and the second detection process to share the calibration data is different, which is embodied in that, in the first embodiment, the first detection process and the second detection process share the calibration data as long as they are used to measure the same detection item of different samples; while in the embodiment, when the detection item executed by the first detection process and the detection item executed by the second detection process are the same detection item, the first detection process and the second detection process share the calibration data only under a part of the detection items, and under another part of the detection items, the first detection process and the second detection process use different calibration data.

[0257] Specifically, the sample analyzer 10 provided by the embodiment comprises a sample dispensing device 100, a reagent dispensing device 200, a sample detection device 300 and a controller 400. The sample dispensing device 100 comprises a first sample dispensing assembly 110 and a second sample dispensing assembly 120, and the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are respectively used to perform the following sample dispensing action: sucking a sample from a sample container and dispensing at least part of the sucked sample into a reaction container; wherein the first sample dispensing assembly 110 comprises a first sample needle 111, and the second sample dispensing assembly 120 comprises a second sample needle 121, and the first sample needle 111 and the second sample needle 121 are two sample needles capable of independently performing the sample dispensing action. The reagent dispensing device 200 is used to perform the following reagent dispensing action: sucking a reagent from a reagent container and dispensing at least part of the sucked reagent into a reaction container. The sample detection device 300 is used to detect a to-be-tested liquid made of at least a sample dispensed by the sample dispensing device 100 and a reagent dispensed by the reagent dispensing device 200. The controller 400 is configured to perform the following first detection process: controlling the first sample dispensing assembly 110 to perform the sample dispensing action, controlling the reagent dispensing device 200 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-tested liquid made of at least the sample dispensed by the first sample dispensing assembly 110 and the reagent dispensed by the reagent dispensing device 200, obtaining first detection data according to detection information fed back by the sample detection device 300, and obtaining a first detection result according to the first detection data and first calibration data. The controller 400 is further configured to perform the following second detection process: controlling the second sample dispensing assembly 120 to perform the sample dispensing action, controlling the reagent dispensing device 200 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-tested liquid made of at least the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and second calibration data. Wherein, the controller 400 is further configured to: when detection items executed by the first detection process and the second detection process are both first detection items, setting the first calibration data and the second calibration data to adopt the same calibration data; when detection items executed by the first detection process and the second detection process are both second detection items, setting the first calibration data and the second calibration data to respectively adopt two different calibration data; and the first detection items and the second detection items are two different detection items. The second detection items are mainly detection items with particularly high consistency requirements. In the embodiment, only under some detection items, when the first detection process and the second detection process are used to detect the same detection item, the calibration data can be shared; and under other detection items, even when the first detection process and the second detection process are used to detect the same detection item, the calibration data cannot be shared.

[0258] As an implementation, the controller 400 is further configured to control the first sample dispensing assembly 110 to aspirate the item calibration sample from the second calibration sample container and dispense into the reaction container, and control the reagent dispensing device 200 to aspirate the reagent from the reagent container and dispense into the reaction container; control the sample detection device 300 to detect the calibration solution made of at least the item calibration sample and the reagent in the reaction container, and obtain the first calibration data corresponding to the first detection item according to the detection information fed back by the sample detection device 300. The controller 400 is configured to control the second sample dispensing assembly 120 to perform the sample dispensing action, control the reagent dispensing device 200 to perform the reagent dispensing action, control the sample detection device 300 to detect the to-be-detected solution made of at least the sample dispensed by the second sample dispensing assembly 120 and the reagent dispensed by the reagent dispensing device 200, obtain the second detection data according to the detection information fed back by the sample detection device 300, and obtain the second detection result according to the second detection data and the first calibration data corresponding to the first detection item.

[0259] In addition to the above, other parts of the sample analyzer 10 provided by the present embodiment can refer to embodiments one to ten, and will not be described in detail here.

[0260] Embodiment twelve:

[0261] Referring to Figures 1 to 4 and Figure 6 It is shown that the sample analyzer 10 provided by the present embodiment is mainly different from the sample analyzer of embodiment one in that the multi-needle system is used for dispensing different objects, which is specifically embodied in that in embodiment one, the multi-needle system is used for dispensing samples; and in the present embodiment, the multi-needle system is used for dispensing reagents.

[0262] Specifically, the sample analyzer 10 provided by the embodiment comprises a sample dispensing device 100, a reagent dispensing device 200, a sample detection device 300 and a controller 400. The sample dispensing device 100 is configured to perform a sample dispensing action of sucking a sample from a sample container and dispensing at least part of the sample into a reaction container. The reagent dispensing device 200 comprises a first reagent dispensing assembly 210 and a second reagent dispensing assembly 220, and the first reagent dispensing assembly 210 and the second reagent dispensing assembly 220 are respectively configured to perform a reagent dispensing action of sucking a reagent from a reagent container and dispensing at least part of the reagent into the reaction container; wherein the first reagent dispensing assembly 210 comprises a first reagent needle, and the second reagent dispensing assembly 220 comprises a second reagent needle, and the first reagent needle and the second reagent needle are two reagent needles capable of independently performing the reagent dispensing action. The sample detection device 300 is configured to detect a to-be-detected liquid made of at least the sample dispensed by the sample dispensing device 100 and the reagent dispensed by the reagent dispensing device 200. The controller 400 is configured to perform a third detection process of controlling the sample dispensing device 100 to perform the sample dispensing action, controlling the first reagent dispensing assembly 210 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-detected liquid made of at least the sample dispensed by the sample dispensing device 100 and the reagent dispensed by the first reagent dispensing assembly 210, obtaining third detection data according to detection information fed back by the sample detection device 300, and obtaining a third detection result according to the third detection data and third calibration data. The controller 400 is further configured to perform a fourth detection process of controlling the sample dispensing device 100 to perform the sample dispensing action, controlling the second reagent dispensing assembly 220 to perform the reagent dispensing action, controlling the sample detection device 300 to detect the to-be-detected liquid made of at least the sample dispensed by the sample dispensing device 100 and the reagent dispensed by the second reagent dispensing assembly 220, obtaining fourth detection data according to detection information fed back by the sample detection device 300, and obtaining a fourth detection result according to the fourth detection data and fourth calibration data. When the detection items performed by the third detection process and the fourth detection process are the same detection items, the third calibration data and the fourth calibration data are the same calibration data. In the embodiment, the first reagent needle and the second reagent needle can be used to perform the reagent dispensing action of the same detection item, and when batch detection of a certain detection item is required, the first reagent needle can be controlled to perform the reagent dispensing action of part of the detection items, the second reagent needle can be controlled to perform the reagent dispensing action of another part of the detection items, and the first reagent needle and the second reagent needle can be controlled to work simultaneously or alternately, so that the first reagent needle and the second reagent needle can be fully utilized to improve the detection efficiency of the sample analyzer 10.In addition, since the first reagent needle and the second reagent needle adopt the same calibration data for calibration when performing the reagent dispensing action of the same reagent of the same detection item, calibration for the first reagent needle and the second reagent needle is not required, thereby facilitating reduction of calibration cost and improvement of calibration efficiency, and good consideration is given to detection efficiency and calibration cost and calibration efficiency.

[0263] As an implementation, the controller 400 is further configured to perform the following item calibration process of the first detection item: control the sample dispensing device 100 to aspirate the item calibration sample from the second calibration sample container and dispense into the reaction container, control the first reagent dispensing assembly 210 to aspirate the reagent from the reagent container and dispense into the reaction container; control the sample detection device 300 to detect the calibration solution made of at least the item calibration sample and the reagent in the reaction container, and obtain the third calibration data corresponding to the first detection item according to the detection information fed back by the sample detection device 300. The controller 400 is further configured to perform the following fourth detection process of the first detection item: control the sample dispensing device 100 to perform the sample dispensing action, control the second reagent dispensing assembly 220 to perform the reagent dispensing action, control the sample detection device 300 to detect the to-be-detected solution made of at least the sample dispensed by the sample dispensing device 100 and the reagent dispensed by the second reagent dispensing assembly, obtain the fourth detection data according to the detection information fed back by the sample detection device 300, and obtain the fourth detection result according to the fourth detection data and the third calibration data corresponding to the first detection item.

[0264] As an embodiment, the sample needle system of the present embodiment is a single sample needle system, i.e., the sample dispensing device 100 comprises a single sample needle and a single sample dispensing power component. Of course, as an alternative embodiment, the sample dispensing device 100 can also be configured as in Embodiment One, i.e., the sample dispensing device 100 comprises a first sample dispensing assembly 110 and a second sample dispensing assembly 120, the first sample dispensing assembly 110 and the second sample dispensing assembly 120 are respectively configured to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least part of the aspirated sample into a reaction container. The first sample dispensing assembly 110 and the second sample dispensing assembly 120 are two dispensing assemblies capable of performing sample dispensing actions independently of each other. The first sample dispensing assembly 110 comprises a first sample needle 111, and the second sample dispensing assembly 120 comprises a second sample needle 121. The first sample needle 111 and the second sample needle 121 are two sample needles capable of performing sample dispensing actions independently of each other. The controller 400 is configured to perform the following first detection process: controlling the first sample dispensing assembly 110 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detection device 300 to detect a to-be-tested liquid made of at least a sample dispensed by the first sample dispensing assembly 110 and a reagent dispensed by the reagent dispensing device 200, obtaining first detection data according to detection information fed back by the sample detection device 300, and obtaining a first detection result according to the first detection data and first calibration data. The controller 400 is also configured to perform the following second detection process: controlling the second sample dispensing assembly 120 to perform a sample dispensing action, controlling the reagent dispensing device 200 to perform a reagent dispensing action, controlling the sample detection device 300 to detect a to-be-tested liquid made of at least a sample dispensed by the second sample dispensing assembly 120 and a reagent dispensed by the reagent dispensing device 200, obtaining second detection data according to detection information fed back by the sample detection device 300, and obtaining a second detection result according to the second detection data and second calibration data. When the detection item performed by the first detection process and the detection item performed by the second detection process are the same detection item, the first calibration data and the second calibration data are the same calibration data. The multi-needle system in the alternative embodiment, including a multi-reagent needle system and a multi-sample needle system, and the multi-reagent needle system can share the calibration data of the same detection item when performing a reagent dispensing action of the detection item, and the multi-sample needle system can also share the calibration data when performing a sample dispensing action of the detection item.

[0265] In addition to the above, other parts of the sample analyzer 10 provided by the present embodiment can refer to Embodiments One to Eleven, which will not be described in detail here.

[0266] Embodiment Thirteen

[0267] The sample analyzer 10 provided by the embodiment differs from the first embodiment mainly in that the multi-needle system is used for different objects of dispensing, which is embodied in that in the first embodiment, the multi-needle system is used for dispensing samples, while in the present embodiment, the multi-needle system is used for dispensing samples and reagents.

[0268] Specifically, the sample analyzer 10 provided by the embodiment comprises a pipetting device, a sample detection device 300, and a controller 400. The pipetting device comprises a first pipetting assembly and a second pipetting assembly, and the first pipetting assembly and the second pipetting assembly are respectively configured to perform liquid dispensing actions of: sucking a sample from a sample container and dispensing at least part of the sample into a reaction container; and sucking a reagent from a reagent container and dispensing at least part of the reagent into the reaction container. The first pipetting assembly comprises a first pipetting needle, and the second pipetting assembly comprises a second pipetting needle. The first pipetting needle and the second pipetting needle are two pipetting needles capable of independently performing liquid dispensing actions. The sample detection device 300 is configured to detect a to-be-detected liquid made of at least the sample and the reagent dispensed by the pipetting device. The controller 400 is configured to perform a fifth detection process of: controlling the first pipetting assembly to perform the liquid dispensing action, controlling the sample detection device 300 to detect the to-be-detected liquid made of at least the sample and the reagent dispensed by the first pipetting assembly, obtaining fifth detection data according to detection information fed back by the sample detection device 300, and obtaining a fifth detection result according to the fifth detection data and fifth calibration data. The controller 400 is also configured to perform a sixth detection process of: controlling the second pipetting assembly to perform the liquid dispensing action, controlling the sample detection device 300 to detect the to-be-detected liquid made of at least the sample and the reagent dispensed by the second pipetting assembly, obtaining sixth detection data according to detection information fed back by the sample detection device 300, and obtaining a sixth detection result according to the sixth detection data and sixth calibration data. When the detection items performed by the fifth detection process and the sixth detection process are the same detection items, the fifth calibration data and the sixth calibration data are the same calibration data. In the embodiment, the first pipetting needle is used to dispense the sample and the reagent, the second pipetting needle is also used to dispense the sample and the reagent, and the first pipetting needle and the second pipetting needle can be used to perform sample dispensing actions and reagent dispensing actions of the same detection item. When batch detection of a certain detection item is required, the first pipetting needle can be controlled to perform sample dispensing actions and reagent dispensing actions of a part of the detection items, and the second pipetting needle can be controlled to perform sample dispensing actions and reagent dispensing actions of another part of the detection items, so that the first pipetting needle and the second pipetting needle can be fully utilized to improve the detection efficiency of the sample analyzer 10. In addition, since the same calibration data is used for calibration when the first pipetting needle and the second pipetting needle perform sample dispensing actions of the same detection item and reagent dispensing actions of the same reagent, calibration of the first pipetting needle and the second pipetting needle is not required, thereby reducing the calibration cost and improving the calibration efficiency, and the detection efficiency, the calibration cost, and the calibration efficiency are well balanced.

[0269] As an implementation, the controller 400 is further configured to control the first detection item to perform a project calibration process as follows: control the first pipetting assembly to aspirate a project calibration sample from a second calibration sample container and dispense into a reaction container, control the first pipetting assembly to aspirate a reagent from a reagent container and dispense into the reaction container; control the sample detection device 300 to detect a calibration solution made at least from the project calibration sample and the reagent in the reaction container, and obtain fifth calibration data corresponding to the first detection item according to the detection information fed back by the sample detection device 300; the controller 400 is configured to perform a sixth detection process of the first detection item as follows: control the second pipetting assembly to perform a liquid dispensing action, control the sample detection device 300 to detect a to-be-detected solution made at least from a sample dispensed by the second pipetting assembly and a reagent, obtain sixth detection data according to the detection information fed back by the sample detection device 300, and obtain a sixth detection result according to the sixth detection data and the fifth calibration data corresponding to the first detection item.

[0270] In addition to the above, other parts of the sample analyzer 10 provided by the present embodiment can refer to Embodiments 1 to 12, and will not be described in detail here.

[0271] The above only describes the preferred embodiments of the present application, and does not limit the patent scope of the present application. Any equivalent structural transformation made under the inventive concept of the present application, or direct / indirect application in other related technical fields, is included in the patent protection scope of the present application.

Claims

1. A sample analyzer, characterized in that: include: A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, wherein the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, wherein the first sample needle and the second sample needle are two sample needles capable of independently performing the sample dispensing action; A reagent dispensing device, the reagent dispensing device is used to perform the following reagent dispensing action: sucking the reagent from the reagent container and dispensing at least part of the sucked reagent into the reaction container; a sample detection device for detecting a test solution prepared from at least the sample distributed by the sample distribution device and the reagent distributed by the reagent distribution device; a controller configured to execute the following first detection process: controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the first sample dispensing assembly and the reagent dispensed by the reagent dispensing device, obtaining first detection data based on detection information fed back by the sample detection device, and obtaining a first detection result based on the first detection data and first calibration data; The controller is further configured to execute the following second detection process: controlling the second sample dispensing component to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtaining second detection data based on detection information fed back by the sample detection device, and obtaining a second detection result based on the second detection data and second calibration data; When the inspection item executed by the first inspection process and the inspection item executed by the second inspection process are the same inspection item, the first calibration data and the second calibration data are the same calibration data.

2. The sample analyzer according to claim 1, wherein: A deviation between a sample dispensing accuracy of the first sample dispensing component and a sample dispensing accuracy of the second sample dispensing component is less than or equal to a first preset value, and the first preset value is greater than or equal to zero and less than or equal to 5%.

3. The sample analyzer according to claim 2, wherein: The first preset value is less than or equal to 2%.

4. The sample analyzer according to any one of claims 1 to 3, wherein: The sample analyzer also includes a dispensing volume detection device, and the controller is further configured to execute the following sample loading calibration process: controlling the first sample dispensing component to absorb the sample loading calibrator and dispense it into a reaction container, and controlling the dispensing volume detection device to detect the dispensing volume of the first calibrator dispensed into the reaction container by the first sample dispensing component; controlling the second sample dispensing component to absorb the sample loading calibrator and dispense it into the reaction container, and controlling the dispensing volume detection device to detect the dispensing volume of the second calibrator dispensed into the reaction container by the second sample dispensing component; and correcting the sample dispensing volume of the first sample dispensing component in executing the sample dispensing action and / or the sample dispensing volume of the second sample dispensing component in executing the sample dispensing action according to the first calibrator dispensing volume and the second calibrator dispensing volume, so that the deviation between the sample dispensing accuracy of the first sample dispensing component and the sample dispensing accuracy of the second sample dispensing component is less than or equal to a first preset value.

5. The sample analyzer according to claim 4, wherein: The correcting the sample dispensing amount of the first sample dispensing component in performing the sample dispensing action and / or the sample dispensing amount of the second sample dispensing component in performing the sample dispensing action according to the first calibrator dispensing amount and the second calibrator dispensing amount includes: Calculating a first deviation value of the second calibrator dispensed amount relative to the first calibrator dispensed amount, and correcting the sample dispensed amount of the second sample dispensing component when performing the sample dispensing action according to the first deviation value; or A second deviation value of the first calibrator dispensed amount relative to the second calibrator dispensed amount is calculated, and the sample dispensed amount of the first sample dispensing component during the sample dispensing action is corrected according to the second deviation value.

6. The sample analyzer according to claim 4, wherein: The correcting the sample dispensing amount of the first sample dispensing component in executing the sample dispensing action and / or the sample dispensing amount of the second sample dispensing component in executing the sample dispensing action according to the first calibrator dispensing amount and the second calibrator dispensing amount includes: calculating a third deviation value of the first calibrator dispensing amount relative to a reference amount, calculating a fourth deviation value of the second calibrator dispensing amount relative to the reference amount, correcting the sample dispensing amount of the first sample dispensing component in executing the sample dispensing action according to the third deviation value, and correcting the sample dispensing amount of the second sample dispensing component in executing the sample dispensing action according to the fourth deviation value; The reference amount is a target dispensing amount of the sample that the sample dispensing device actually needs to dispense into the reaction container during the sample dispensing operation, or there is a preset difference between the reference amount and the target dispensing amount of the sample that the sample dispensing device actually needs to dispense into the reaction container during the sample dispensing operation.

7. The sample analyzer according to any one of claims 4 to 6, wherein: The correcting the sample dispensing amount of the first sample dispensing component in performing the sample dispensing action and / or the sample dispensing amount of the second sample dispensing component in performing the sample dispensing action according to the first calibrator dispensing amount and the second calibrator dispensing amount includes: Calculating a first deviation of the second calibrator dispensed amount relative to the first calibrator dispensed amount, obtaining a first correction parameter based on the first deviation, and calculating a corrected sample dispensed amount of the first sample dispensing assembly based on a target dispensed amount of the sample that the sample dispensing device actually needs to dispense to the reaction vessel during the sample dispensing operation and the first correction parameter, while maintaining the sample dispensed amount of the second sample dispensing assembly unchanged; or Calculating a second deviation value of the first calibrator dispensed amount relative to the second calibrator dispensed amount, obtaining a second correction parameter based on the second deviation value, and calculating a corrected sample dispensed amount of the second sample dispensing assembly based on a target dispensed amount of the sample that the sample dispensing device actually needs to dispense to the reaction vessel during the sample dispensing operation and the second correction parameter, while maintaining the sample dispensed amount of the first sample dispensing assembly unchanged; or Calculate a third deviation value of the first calibrator dispensed amount relative to the reference amount, obtain a third correction parameter based on the third deviation value, and calculate the corrected sample dispensed amount of the first sample dispensing component based on the target dispensed amount of the sample that the sample dispensing device actually needs to dispense to the reaction container in the sample dispensing action and the third correction parameter; calculate a fourth deviation value of the second calibrator dispensed amount relative to the reference amount, obtain a fourth correction parameter based on the fourth deviation value, and calculate the corrected sample dispensed amount of the second sample dispensing component based on the target dispensed amount and the fourth correction parameter; wherein the reference amount is the target dispensed amount, or there is a preset difference between the reference amount and the target dispensed amount.

8. The sample analyzer according to claim 4, wherein: The dispensing amount detection device is a weighing device, and controlling the dispensing amount detection device to detect the dispensing amount of the first calibrator dispensed into the reaction vessel by the first sample dispensing assembly includes: controlling the weighing device to weigh the weight of the added calibrator dispensed into the reaction vessel by the first sample dispensing assembly, and obtaining the dispensing amount of the first calibrator dispensed into the reaction vessel by the first sample dispensing assembly based on the weight information fed back by the weighing device; The control of the distribution amount detection device to detect the distribution amount of the second calibrant distributed by the second sample dispensing component into the reaction container includes: controlling the weighing device to weigh the weight of the added calibrant distributed by the second sample dispensing component into the reaction container, and obtaining the distribution amount of the second calibrant distributed by the second sample dispensing component into the reaction container based on the weight information fed back by the weighing device.

9. The sample analyzer according to claim 4, wherein: The distribution amount detection device is a first optical detection device, and the sample-added calibrator is a pigment solution; the first sample dispensing component is controlled to absorb the sample-added calibrator and distribute it into the reaction container, and the distribution amount detection device is controlled to detect the distribution amount of the first calibrator distributed by the first sample dispensing component into the reaction container, including: controlling the first sample dispensing component to absorb the pigment solution and distribute it into the reaction container, controlling the first optical detection device to detect the absorbance of the pigment solution distributed by the first sample dispensing component into the reaction container, and obtaining the distribution amount of the first calibrator distributed by the first sample dispensing component into the reaction container; the second sample dispensing component is controlled to absorb the sample-added calibrator and distribute it into the reaction container, and the distribution amount detection device is controlled to detect the distribution amount of the second calibrator distributed by the second sample dispensing component into the reaction container, including: controlling the second sample dispensing component to absorb the pigment solution and distribute it into the reaction container, controlling the first optical detection device to detect the absorbance of the pigment solution distributed by the second sample dispensing component into the reaction container, and obtaining the distribution amount of the second calibrator distributed by the second sample dispensing component into the reaction container; or The distribution amount detection device is a first optical detection device, and the sample-added calibrator is a pigment solution; the control of the first sample dispensing component to absorb the sample-added calibrator and distribute it in the reaction container, and the control of the distribution amount detection device to detect the distribution amount of the first calibrator distributed by the first sample dispensing component in the reaction container, include: controlling the first sample dispensing component to absorb the pigment solution and distribute it in the reaction container, controlling the reagent dispensing device to absorb the diluent and distribute it in the reaction container, controlling the first optical detection device to detect the absorbance of the first mixed liquid formed by mixing the pigment solution distributed in the reaction container by the first sample dispensing component and the diluent distributed in the reaction container by the reagent dispensing device, and obtaining the absorbance of the first mixed liquid distributed in the reaction container by the first sample dispensing component. The first calibrator dispensing amount in the device; the controlling the second sample dispensing component to absorb the sampled calibrator and dispense it into the reaction container, controlling the dispensing amount detection device to detect the second calibrator dispensing amount dispensed into the reaction container by the second sample dispensing component, including: controlling the second sample dispensing component to absorb the pigment solution and dispense it into the reaction container, controlling the reagent dispensing device to absorb the diluent and dispense it into the reaction container, controlling the first optical detection device to detect the absorbance of a second mixed liquid formed by mixing at least the pigment solution dispensed into the reaction container by the second sample dispensing component and the diluent dispensed into the reaction container by the reagent dispensing device, and obtaining the second calibrator dispensing amount dispensed into the reaction container by the second sample dispensing component; or, The distribution amount detection device is a first optical detection device, and the sample-added calibrator is a diluent; the control of the first sample dispensing component to absorb the sample-added calibrator and distribute it in the reaction container, and the control of the distribution amount detection device to detect the distribution amount of the first calibrator distributed by the first sample dispensing component in the reaction container, include: controlling the first sample dispensing component to absorb the diluent and distribute it in the reaction container, controlling the reagent dispensing device to absorb the pigment solution and distribute it in the reaction container, controlling the first optical detection device to detect the absorbance of a third mixed liquid formed by mixing at least the diluent distributed in the reaction container by the first sample dispensing component and the pigment solution distributed in the reaction container by the reagent dispensing device, and obtaining the absorbance of the third mixed liquid distributed in the reaction container by the first sample dispensing component. The dispensing amount of the first calibrator in the container; the controlling the second sample dispensing component to absorb the sampled calibrator and distribute it into the reaction container, and controlling the dispensing amount detection device to detect the dispensing amount of the second calibrator distributed by the second sample dispensing component into the reaction container, including: controlling the second sample dispensing component to absorb the diluent and distribute it into the reaction container, controlling the reagent dispensing device to absorb the pigment solution and distribute it into the reaction container, controlling the first optical detection device to detect the absorbance of a fourth mixed liquid formed by mixing at least the diluent distributed into the reaction container by the second sample dispensing component and the pigment solution distributed into the reaction container by the reagent dispensing device, to obtain the dispensing amount of the second calibrator distributed into the reaction container by the second sample dispensing component.

10. The sample analyzer according to claim 4, wherein: The distribution amount detection device is a second optical detection device, and the sample addition calibrator is a first marker reagent with a luminescent marker; The sample analyzer further comprises a substrate dispensing device for dispensing a luminescent substrate reagent into the reaction container; The controlling the first sample dispensing component to draw up the sampled calibrator and dispense it into the reaction vessel, and controlling the dispensed amount detection device to detect the dispensed amount of the first calibrator dispensed into the reaction vessel by the first sample dispensing component, comprises: controlling the first sample dispensing component to draw up the first marker reagent and dispense it into the reaction vessel, controlling the substrate dispensing device to dispense the luminescent substrate reagent into the reaction vessel, and controlling the second optical detection device to detect the luminescence intensity of a first reaction solution prepared from at least the first marker reagent dispensed into the reaction vessel by the first sample dispensing component and the luminescent substrate reagent dispensed into the reaction vessel by the substrate dispensing device, thereby obtaining the dispensed amount of the first calibrator dispensed into the reaction vessel by the first sample dispensing component; The controlling the second sample dispensing component to aspirate the sample calibrator and dispense it into the reaction vessel, and controlling the dispensed amount detection device to detect the dispensed amount of the second calibrator dispensed into the reaction vessel by the second sample dispensing component, includes: controlling the second sample dispensing component to aspirate the first marker reagent and dispense it into the reaction vessel, controlling the substrate dispensing device to dispense the luminescent substrate reagent into the reaction vessel, and controlling the second optical detection device to detect the luminescent intensity of a second reaction solution made of at least the first marker reagent dispensed into the reaction vessel by the second sample dispensing component and the luminescent substrate reagent dispensed into the reaction vessel by the substrate dispensing device, to obtain the dispensed amount of the second calibrator dispensed into the reaction vessel by the second sample dispensing component.

11. The sample analyzer according to claim 10, wherein: The reagent dispensing device performs the reagent dispensing action including: drawing a magnetic bead reagent with magnetic beads from a first reagent container and dispensing it into a reaction container, and drawing a second marker reagent with a luminescent marker from a second reagent container and dispensing it into the reaction container; The reaction device is used to carry a reaction container to incubate a liquid containing at least a sample, the magnetic bead reagent, and the second marker reagent to produce a third reaction liquid; The sample analyzer further includes a magnetic separation device, which is used to perform a magnetic separation and cleaning operation on the third reaction liquid to produce a fourth reaction liquid; The substrate dispensing device is further used to dispense a luminescent substrate reagent into the fourth reaction liquid, so that the fourth reaction liquid and the luminescent substrate reagent are combined to form the test liquid; The sample detection device is used to detect the luminescence intensity of the liquid to be tested; The sample addition calibration process differs from the first detection process and the second detection process in at least one of the following aspects: the components of the first marker reagent are different from the components of the second marker reagent, the concentration of the first marker reagent is different from the concentration of the second marker reagent, the dispensed amount of the first marker reagent is different from the dispensed amount of the second marker reagent, the dispensed amount of the luminescent substrate reagent is different, the incubation time is different, and the incubation temperature is different.

12. The sample analyzer according to claim 4, wherein: The sample analyzer is pre-stored with a first preset condition, the first preset condition including at least one of the following: a first preset time period has elapsed since the last execution of the sample addition calibration process; information on the completion of troubleshooting of the first sample dispensing component and / or the second sample dispensing component has been obtained; information on the completion of loading of the first sample dispensing component and / or the second sample dispensing component has been obtained; a first preset time point of a first preset maintenance cycle has been reached; The controller is further configured to: execute the sample addition calibration process when the first preset condition is met.

13. The sample analyzer according to any one of claims 1 to 3, wherein: The first sample dispensing assembly and the second sample dispensing assembly share at least some components.

14. The sample analyzer according to claim 13, wherein: The first sample dispensing assembly further includes a first aspiration power component, the first aspiration power component being used to provide a driving force for the first sample needle to perform an aspiration action; The second sample dispensing assembly further includes a second aspiration power component, which is used to provide a driving force for the second sample needle to perform an aspiration action; The first suction and injection power component and the second suction and injection power component are the same suction and injection power component.

15. The sample analyzer according to claim 1, wherein: The first sample needle is configured with a first identification code, and the first identification code is associated with a sample addition correction parameter of the first sample needle; the sample analyzer further includes a first information acquisition component, and the first information acquisition component is used to identify the first identification code; the controller is further configured to: obtain the sample addition correction parameter of the first sample needle according to information fed back by the first information acquisition component when identifying the first identification code; correct the sample distribution amount of the first sample dispensing component in performing the sample distribution action according to at least the sample addition correction parameter of the first sample needle, so that the deviation of the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value; and / or, The second sample needle is configured with a second identification code, and the second identification code is associated with a sample addition correction parameter of the second sample needle; the sample analyzer also includes a first information acquisition component, and the first information acquisition component is used to identify the second identification code; the controller is further configured to: obtain the sample addition correction parameter of the second sample needle based on the information fed back by the first information acquisition component when identifying the second identification code; and correct the sample distribution amount of the second sample dispensing component when executing the sample distribution action at least based on the sample addition correction parameter of the second sample needle, so that the deviation between the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value.

16. The sample analyzer according to claim 15, wherein: The controller is further configured to: before controlling the first sample needle to perform the first sample dispensing action on the sample analyzer, obtain a sample addition calibration parameter of the first sample needle based on information fed back by the first information acquisition component identifying the first identification code; and / or, The controller is further configured to: before controlling the second sample needle to perform the first sample dispensing action on the sample analyzer, obtain a sample addition calibration parameter of the second sample needle based on information fed back by the first information acquisition component identifying the second identification code.

17. The sample analyzer according to any one of claims 1 to 3 or 15 or 16, wherein: The first sample dispensing component further includes a first aspiration power component, which is used to provide a driving force for the first sample needle to perform an aspiration action; the first aspiration power component is configured with a third identification code, and the third identification code is associated with a sample addition correction parameter of the first aspiration power component; the sample analyzer further includes a first information acquisition component, which is used to identify the third identification code, and the controller is further configured to: obtain the sample addition correction parameter of the first aspiration power component according to the information fed back by the first information acquisition component when identifying the third identification code; correct the sample distribution amount of the first sample dispensing component in performing the sample distribution action according to the sample addition correction parameter of the first aspiration power component, so that the deviation of the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value; and / or, The second sample dispensing component also includes a second aspiration power component, which is used to provide driving force for the second sample needle to perform the aspiration action; the second aspiration power component is configured with a fourth identification code, and the fourth identification code is associated with the sample addition correction parameters of the second aspiration power component; the sample analyzer also includes a first information acquisition component, which is used to identify the fourth identification code, and the controller is further configured to: obtain the sample addition correction parameters of the second aspiration power component based on the information feedback when the first information acquisition component identifies the fourth identification code; and correct the sample distribution amount of the second sample dispensing component in performing the sample distribution action according to the sample addition correction parameters of the second aspiration power component, so that the deviation between the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value.

18. The sample analyzer according to claim 17, wherein: The controller is further configured to: before controlling the first aspiration power component to perform the first sample dispensing action on the sample analyzer, obtain a sample addition calibration parameter of the first aspiration power component based on information fed back by the first information acquisition component identifying the third identification code; and / or, The controller is further configured to: before controlling the second aspiration power component to perform the first sample dispensing action on the sample analyzer, obtain a sample addition correction parameter of the second aspiration power component based on information fed back by the first information acquisition component identifying the fourth identification code.

19. The sample analyzer according to any one of claims 1 to 3 or 15 or 16, wherein: The sample analyzer further includes a reaction device, the reaction device being used to carry a reaction container to incubate the sample and reagent in the reaction container, and the controller is further configured to: control the same reagent dispensing device to respectively perform the reagent dispensing action in the first detection process and the reagent dispensing action in the second detection process; Control the same reaction device to incubate the sample and reagent in the first detection process and the sample and reagent in the second detection process respectively; control the same sample detection device to detect the liquid to be tested in the first detection process and the liquid to be tested in the second detection process respectively.

20. The sample analyzer according to claim 19, wherein: The reagent dispensing device performs the reagent dispensing action including: drawing the magnetic bead reagent from the first reagent container and dispensing it into the reaction container, and drawing the second marker reagent from the second reagent container and dispensing it into the reaction container; The reaction device is used to carry a reaction container to incubate a liquid containing at least a sample, the magnetic bead reagent, and the second marker reagent to produce a third reaction liquid; The sample analyzer further includes a magnetic separation device and a substrate dispensing device, wherein the magnetic separation device is used to perform a magnetic separation and cleaning operation on the third reaction liquid to produce a fourth reaction liquid; The substrate dispensing device is used to perform the following substrate dispensing action: aspirating the luminescent substrate reagent from the substrate reagent container, and dispensing at least a portion of the aspirated luminescent substrate reagent into the reaction container, so that the fourth reaction liquid and the luminescent substrate reagent are combined to form the test liquid; The sample detection device is used to detect the luminescence intensity of the liquid to be tested; The controller is also configured to: control the same magnetic separation device to respectively perform the magnetic separation and cleaning operations in the first detection process and the magnetic separation and cleaning operations in the second detection process; control the same substrate dispensing device to respectively perform the substrate dispensing action in the first detection process and the substrate dispensing action in the second detection process.

21. The sample analyzer according to any one of claims 1 to 3 or 15 or 16, wherein: The controller is further configured to execute the following project calibration process for the first test project: controlling the first sample dispensing assembly to draw a project calibrator from a second calibrator container and dispense it into a reaction container, controlling the reagent dispensing device to draw a reagent from a reagent container and dispense it into the reaction container; controlling the sample detection device to detect a calibration solution in the reaction container made of at least the project calibrator and the reagent, and obtaining first calibration data corresponding to the first test project based on detection information fed back by the sample detection device; The controller is also configured to execute the following second detection process for the first detection item: control the second sample dispensing component to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtain second detection data based on the detection information fed back by the sample detection device, and obtain a second detection result based on the second detection data and the first calibration data corresponding to the first detection item.

22. A sample analyzer, characterized in that: include: A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, wherein the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, wherein the first sample needle and the second sample needle are two sample needles capable of independently performing the sample dispensing action; A reagent dispensing device, the reagent dispensing device is used to perform the following reagent dispensing action: sucking the reagent from the reagent container and dispensing at least part of the sucked reagent into the reaction container; a sample detection device for detecting a test solution made of at least the sample distributed by the sample distribution device and the reagent distributed by the reagent distribution device; A controller configured to execute the following project calibration process for a first test project: controlling the first sample dispensing assembly to draw a project calibrator from a second calibrator container and dispense it into a reaction container, controlling the reagent dispensing device to draw a reagent from a reagent container and dispense it into the reaction container; controlling the sample detection device to detect a calibration solution in the reaction container made of at least the project calibrator and the reagent, and obtaining first calibration data corresponding to the first test project based on detection information fed back by the sample detection device; The controller is also configured to execute the following second detection process for the first detection item: control the second sample dispensing component to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtain second detection data based on the detection information fed back by the sample detection device, and obtain a second detection result based on the second detection data and the first calibration data corresponding to the first detection item.

23. The sample analyzer according to claim 22, wherein: The sample analyzer also includes a dispensing volume detection device, and the controller is further configured to execute the following sample loading calibration process: controlling the first sample dispensing component to absorb the sample loading calibrator and dispense it into a reaction container, and controlling the dispensing volume detection device to detect the dispensing volume of the first calibrator dispensed into the reaction container by the first sample dispensing component; controlling the second sample dispensing component to absorb the sample loading calibrator and dispense it into the reaction container, and controlling the dispensing volume detection device to detect the dispensing volume of the second calibrator dispensed into the reaction container by the second sample dispensing component; and correcting the sample dispensing volume of the first sample dispensing component in executing the sample dispensing action and / or the sample dispensing volume of the second sample dispensing component in executing the sample dispensing action according to the first calibrator dispensing volume and the second calibrator dispensing volume, so that the deviation between the sample dispensing accuracy of the first sample dispensing component and the sample dispensing accuracy of the second sample dispensing component is less than or equal to a first preset value.

24. The sample analyzer according to claim 22 or 23, wherein: The first sample dispensing assembly further includes a first aspiration power component, the first aspiration power component being used to provide a driving force for the first sample needle to perform an aspiration action; The second sample dispensing assembly further includes a second aspiration power component, which is used to provide a driving force for the second sample needle to perform an aspiration action; The first suction and injection power component and the second suction and injection power component are the same suction and injection power component.

25. The sample analyzer according to claim 22 or 23, wherein: The first sample needle is configured with a first identification code, and the first identification code is associated with a sample addition correction parameter of the first sample needle; the sample analyzer further includes a first information acquisition component, and the first information acquisition component is used to identify the first identification code; the controller is further configured to: obtain the sample addition correction parameter of the first sample needle according to information fed back by the first information acquisition component when identifying the first identification code; correct the sample distribution amount of the first sample dispensing component in performing the sample distribution action according to at least the sample addition correction parameter of the first sample needle, so that the deviation of the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value; and / or, The second sample needle is configured with a second identification code, and the second identification code is associated with a sample addition correction parameter of the second sample needle; the sample analyzer also includes a first information acquisition component, and the first information acquisition component is used to identify the second identification code; the controller is further configured to: obtain the sample addition correction parameter of the second sample needle based on the information fed back by the first information acquisition component when identifying the second identification code; and correct the sample distribution amount of the second sample dispensing component when executing the sample distribution action at least based on the sample addition correction parameter of the second sample needle, so that the deviation between the sample distribution accuracy of the first sample dispensing component and the sample distribution accuracy of the second sample dispensing component is less than or equal to a first preset value.

26. A sample analyzer, characterized in that: include: A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, wherein the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, wherein the first sample needle and the second sample needle are two sample needles capable of independently performing the sample dispensing action; A reagent dispensing device, the reagent dispensing device is used to perform the following reagent dispensing action: sucking the reagent from the reagent container and dispensing at least part of the sucked reagent into the reaction container; a sample detection device for detecting a test solution made of at least the sample distributed by the sample distribution device and the reagent distributed by the reagent distribution device; a controller configured to execute the following first detection process: controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the first sample dispensing assembly and the reagent dispensed by the reagent dispensing device, obtaining first detection data based on detection information fed back by the sample detection device, and obtaining a first detection result based on the first detection data and first calibration data; The controller is further configured to execute the following second detection process: controlling the second sample dispensing component to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtaining second detection data based on detection information fed back by the sample detection device, and obtaining a second detection result based on the second detection data and second calibration data; Wherein, the sample analyzer is configured with a first working mode and a second working mode; In the first working mode, the controller is configured to: when the detection item performed by the first detection process and the detection item performed by the second detection process are the same detection item, set the first calibration data and the second calibration data to use the same calibration data; In the second working mode, the controller is configured to: when the detection items executed by the first detection process and the detection items executed by the second detection process are the same detection items, set the first calibration data and the second calibration data to use two different calibration data respectively.

27. The sample analyzer according to claim 26, wherein: The controller is configured to execute the following project calibration process for the first test project: controlling the first sample dispensing assembly to draw a project calibrator from a second calibrator container and dispense it into a reaction container, controlling the reagent dispensing device to draw a reagent from a reagent container and dispense it into the reaction container; controlling the sample detection device to detect a calibration solution in the reaction container made of at least the project calibrator and the reagent, and obtaining first calibration data corresponding to the first test project based on detection information fed back by the sample detection device; In the first working mode, the controller is configured to execute the following second detection process of the first detection item: control the second sample dispensing component to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtain second detection data based on the detection information fed back by the sample detection device, and obtain a second detection result based on the second detection data and the first calibration data corresponding to the first detection item.

28. A sample analyzer, characterized in that: include: A sample dispensing device, comprising a first sample dispensing assembly and a second sample dispensing assembly, wherein the first sample dispensing assembly and the second sample dispensing assembly are respectively configured to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; wherein the first sample dispensing assembly comprises a first sample needle, and the second sample dispensing assembly comprises a second sample needle, wherein the first sample needle and the second sample needle are two sample needles capable of independently performing the sample dispensing action; A reagent dispensing device, the reagent dispensing device is used to perform the following reagent dispensing action: sucking the reagent from the reagent container and dispensing at least part of the sucked reagent into the reaction container; a sample detection device for detecting a test solution made of at least the sample distributed by the sample distribution device and the reagent distributed by the reagent distribution device; a controller configured to execute the following first detection process: controlling the first sample dispensing assembly to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the first sample dispensing assembly and the reagent dispensed by the reagent dispensing device, obtaining first detection data based on detection information fed back by the sample detection device, and obtaining a first detection result based on the first detection data and first calibration data; The controller is further configured to execute the following second detection process: controlling the second sample dispensing component to perform the sample dispensing action, controlling the reagent dispensing device to perform the reagent dispensing action, controlling the sample detection device to detect a test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtaining second detection data based on detection information fed back by the sample detection device, and obtaining a second detection result based on the second detection data and second calibration data; In which, the controller is also configured to: when the detection items executed by the first detection process and the detection items executed by the second detection process are both first detection items, set the first calibration data and the second calibration data to use the same calibration data; when the detection items executed by the first detection process and the detection items executed by the second detection process are both second detection items, set the first calibration data and the second calibration data to use two different calibration data respectively; the first detection item and the second detection item are two different detection items.

29. The sample analyzer according to claim 28, wherein: The controller is further configured to: The controller is further configured to execute the following project calibration process for the first test item: control the first sample dispensing component to draw the project calibrator from the second calibrator container and dispense it into the reaction container, control the reagent dispensing device to draw the reagent from the reagent container and dispense it into the reaction container; control the sample detection device to detect the calibration solution prepared by at least the project calibrator and the reagent in the reaction container, and obtain first calibration data corresponding to the first test item based on the detection information fed back by the sample detection device; The controller is configured to execute the following second detection process for the first detection item: control the second sample dispensing component to perform the sample dispensing action, control the reagent dispensing device to perform the reagent dispensing action, control the sample detection device to detect the test liquid made of at least the sample dispensed by the second sample dispensing component and the reagent dispensed by the reagent dispensing device, obtain second detection data based on the detection information fed back by the sample detection device, and obtain a second detection result based on the second detection data and the first calibration data corresponding to the first detection item.

30. A sample analyzer, characterized in that: include: A sample dispensing device, the sample dispensing device is used to perform the following sample dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; A reagent dispensing device, comprising a first reagent dispensing assembly and a second reagent dispensing assembly, wherein the first reagent dispensing assembly and the second reagent dispensing assembly are respectively configured to perform the following reagent dispensing actions: aspirating a reagent from a reagent container and dispensing at least a portion of the aspirated reagent into a reaction container; wherein the first reagent dispensing assembly comprises a first reagent needle, and the second reagent dispensing assembly comprises a second reagent needle, wherein the first reagent needle and the second reagent needle are two reagent needles capable of independently performing the reagent dispensing action; a sample detection device for detecting a test solution made of at least the sample distributed by the sample distribution device and the reagent distributed by the reagent distribution device; a controller configured to execute the following third detection process: controlling the sample dispensing device to perform the sample dispensing action, controlling the first reagent dispensing assembly to perform the reagent dispensing action, controlling the sample detection device to detect a test solution made of at least the sample dispensed by the sample dispensing device and the reagent dispensed by the first reagent dispensing assembly, obtaining third detection data based on detection information fed back by the sample detection device, and obtaining a third detection result based on the third detection data and third calibration data; The controller is further configured to execute the following fourth detection process: controlling the sample dispensing device to perform the sample dispensing action, controlling the second reagent dispensing assembly to perform the reagent dispensing action, controlling the sample detection device to detect a test solution made of at least the sample dispensed by the sample dispensing device and the reagent dispensed by the second reagent dispensing assembly, obtaining fourth detection data based on detection information fed back by the sample detection device, and obtaining a fourth detection result based on the fourth detection data and fourth calibration data; When the inspection item executed by the third inspection process is the same as the inspection item executed by the fourth inspection process, the third calibration data and the fourth calibration data are the same calibration data.

31. The sample analyzer according to claim 30, wherein: The controller is further configured to execute the following project calibration process for the first test item: controlling the sample dispensing device to draw the project calibrator from the second calibrator container and dispense it into the reaction container, controlling the first reagent dispensing assembly to draw the reagent from the reagent container and dispense it into the reaction container; controlling the sample detection device to detect the calibration solution in the reaction container made of at least the project calibrator and the reagent, and obtaining third calibration data corresponding to the first test item based on the detection information fed back by the sample detection device; The controller is further configured to execute the following fourth detection process for the first detection item: controlling the sample dispensing device to perform the sample dispensing action, controlling the second reagent dispensing component to perform the reagent dispensing action, controlling the sample detection device to detect the test liquid made of at least the sample dispensed by the sample dispensing device and the reagent dispensed by the second reagent dispensing component, obtaining fourth detection data based on the detection information fed back by the sample detection device, and obtaining a fourth detection result based on the fourth detection data and the third calibration data corresponding to the first detection item.

32. A sample analyzer, characterized in that: include: A pipetting device, comprising a first pipetting assembly and a second pipetting assembly, wherein the first pipetting assembly and the second pipetting assembly are respectively configured to perform the following liquid dispensing actions: aspirating a sample from a sample container and dispensing at least a portion of the aspirated sample into a reaction container; and aspirating a reagent from a reagent container and dispensing at least a portion of the aspirated reagent into the reaction container; the first pipetting assembly comprising a first pipetting needle, and the second pipetting assembly comprising a second pipetting needle, wherein the first pipetting needle and the second pipetting needle are two pipetting needles capable of independently performing the liquid dispensing actions; a sample detection device for detecting a test liquid prepared by at least the sample dispensed by the pipetting device and the reagent; a controller configured to execute the following fifth detection process: controlling the first pipetting assembly to perform the liquid dispensing action, controlling the sample detection device to detect the test liquid prepared by at least the sample and reagent dispensed by the first pipetting assembly, obtaining fifth detection data based on detection information fed back by the sample detection device, and obtaining a fifth detection result based on the fifth detection data and fifth calibration data; The controller is further configured to execute the following sixth detection process: controlling the second pipetting assembly to perform the liquid dispensing action, controlling the sample detection device to detect the test liquid prepared by at least the sample and reagent dispensed by the second pipetting assembly, obtaining sixth detection data based on detection information fed back by the sample detection device, and obtaining a sixth detection result based on the sixth detection data and sixth calibration data; When the inspection item executed in the fifth inspection process is the same as the inspection item executed in the sixth inspection process, the fifth calibration data and the sixth calibration data are the same calibration data.

33. The sample analyzer according to claim 32, wherein: The controller is further configured to: The controller is further configured to execute the following project calibration process for the first test item: control the first pipetting component to draw the project calibrator from the second calibrator container and dispense it into the reaction container, control the first pipetting component to draw the reagent from the reagent container and dispense it into the reaction container; control the sample detection device to detect the calibration liquid prepared by at least the project calibrator and the reagent in the reaction container, and obtain fifth calibration data corresponding to the first test item based on the detection information fed back by the sample detection device; The controller is configured to execute the following sixth detection process for the first detection item: controlling the second pipetting component to perform the liquid dispensing action, controlling the sample detection device to detect the test liquid made of at least the sample and reagent dispensed by the second pipetting component, obtaining sixth detection data based on the detection information fed back by the sample detection device, and obtaining a sixth detection result based on the sixth detection data and the fifth calibration data corresponding to the first detection item.

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