A high-precision implantable blood pressure monitoring system

Abstract

The embodiment of the present disclosure provides a high-precision implantable blood pressure monitoring system. The blood pressure monitoring system applied to the field of blood pressure monitoring comprises a pressure sensor, a wireless transmission module and a sensor support. The pressure sensor is arranged on the sensor support and fixed to the inner side of a blood vessel by the sensor support. The wireless transmission module is connected with the pressure sensor and used for receiving and externally transmitting monitoring data. The blood pressure monitoring system integrates a pressure measuring module and a flow rate measuring module on the same substrate, improves system integration, reduces the number of implanted monitors, improves detection precision and provides more comprehensive monitoring data for doctors.

Description

TECHNICAL FIELD

[0001] The present disclosure relates to the field of blood pressure monitoring, in particular to a high-precision implantable blood pressure monitoring system. BACKGROUND

[0002] In the current field of medical monitoring technology, implantable blood pressure monitoring systems, as an advanced non-invasive alternative, have been widely used in continuous and accurate blood pressure monitoring, especially in the management of chronic diseases such as hypertension, heart failure, etc. However, the traditional implantable blood pressure monitoring system has significant limitations in design, mainly reflected in the singleness of monitoring parameters and the lack of technical integration. Specifically, the traditional system mainly relies on pressure sensors to collect and transmit blood pressure data, although it can meet the basic blood pressure monitoring needs, but ignores the synchronous monitoring of blood flow rate, a key physiological parameter. Blood flow rate not only directly reflects the heart pumping function and blood vessel status, but also is an important indicator for evaluating blood circulation efficiency and predicting cardiovascular events. Therefore, single monitoring of blood pressure data is insufficient in the accurate diagnosis and treatment plan formulation of complex cases such as vascular stenosis, arteriosclerosis, and heart failure. In addition, the traditional implantable blood pressure monitoring system has a short board in device integration, usually requiring multiple independent components (such as sensors, batteries, data processing units, etc.) to work together. Due to the mutual interference between components and the influence of environmental factors (such as body temperature changes, motion state), the detection accuracy of the system is also easily affected, making it difficult to ensure long-term, stable and high-precision monitoring.

[0003] Therefore, the present disclosure integrates flow rate or temperature measurement under the premise of ensuring accurate blood pressure measurement, and provides a high-precision implantable blood pressure monitoring system. SUMMARY

[0004] The present disclosure provides a high-precision implantable blood pressure monitoring system, which solves the technical problem of the singleness of monitoring parameters and the lack of technical integration of the traditional implantable blood pressure monitoring system, limiting its application in complex cases.

[0005] A high-precision implantable blood pressure monitoring system, comprising: a pressure sensor, a wireless transmission module, a sensor support; the pressure sensor is arranged on the sensor support and fixed to the inside of the blood vessel by the sensor support; the wireless transmission module is connected with the pressure sensor, used for receiving and transmitting monitoring data outward;

[0006] The pressure sensor comprises a main body, a first pressure sensing diaphragm and a second pressure sensing diaphragm; the main body comprises a base, a first pressure sensing groove, a second pressure sensing groove and a rectangular through hole; the base is a rectangular solid; the first pressure sensing groove and the second pressure sensing groove are both circular grooves with the same radial dimension, and the first pressure sensing groove and the second pressure sensing groove are both arranged on the top surface of the base and arranged side by side along the long side direction of the top surface of the base; the side surface of the base is provided with the rectangular through hole, the extension direction of the rectangular through hole is parallel to the short side direction of the base; the rectangular through hole is located at the bottom of the second pressure sensing groove and communicates with the second pressure sensing groove; the first pressure sensing diaphragm and the second pressure sensing diaphragm are both circular diaphragms with the same size, the first pressure sensing diaphragm is sealingly arranged at the top of the first pressure sensing groove, and the second pressure sensing diaphragm is sealingly arranged at the top of the second pressure sensing groove.

[0007] Optionally, the first pressure sensing diaphragm and the second pressure sensing diaphragm each comprise an elastic diaphragm and a pressure sensing resistor; the pressure sensing resistor is arranged on the surface of the elastic diaphragm; the pressure sensing resistor is composed of a plurality of bending portions connected in series, the shape of the bending portion is Π-shaped; the elastic diaphragm is divided into four regions of upper, lower, left and right, wherein the upper and lower portions are each provided with three bending portions, the left portion is provided with three bending portions, and the right portion is provided with two bending portions; the lead-in end and the lead-out end of the pressure sensing resistor are respectively connected with the two bending portions provided in the right portion; the bending portions of the upper and lower regions respectively extend along the vertical direction of the elastic diaphragm, and the bending portions of the left and right regions respectively extend along the horizontal direction of the elastic diaphragm; the bending portions of the upper and lower regions are perpendicular to the bending portions of the left and right regions.

[0008] Optionally, the pressure sensor further comprises a flow rate detection module, the flow rate detection module comprises a human-shaped elastic sheet, a rectangular support body, a strain resistor and a circular through hole; the rectangular support body is a rectangular hollow body and its left and right ends are through, the upper and lower sides of the rectangular support body are each provided with a through hole; the left and right sides of the rectangular support body are each provided with the human-shaped elastic sheet, and the human-shaped elastic sheet is provided with the strain resistor.

[0009] Optionally, the size of the rectangular support body matches the size of the rectangular through hole, and the rectangular support body is arranged inside the rectangular through hole.

[0010] Optionally, the strain resistor is composed of a plurality of bending portions connected in series; the human-shaped elastic sheet comprises two bending portions and a vertical portion, the bending portions of the strain resistor are arranged at the intersection of the bending portions and the vertical portion of the human-shaped elastic sheet; the side surface of the rectangular support body is provided with a communication groove, and a wire is arranged in the communication groove for connecting the strain resistors in the human-shaped elastic sheets on the left and right sides of the rectangular support body in series.

[0011] Optionally, the top surface of the base is provided with a plurality of terminal, the first pressure sensitive diaphragm, the second pressure sensitive diaphragm and the strain resistance on the human-shaped elastic sheet are connected to the corresponding terminal respectively, and the connection with the wireless transmission module is realized through the terminal.

[0012] Optionally, the wireless transmission module is arranged on the sensor support or between the subcutaneous fat layer and the dermis layer; the wireless transmission module is integrated with a receiving coil, a processing module, a power supply circuit, an energy storage module and a signal transmitting module.

[0013] Optionally, the sensor support comprises a sensor support plate and a retractable elastic frame; the sensor support plate and the retractable elastic frame are integrally formed; the two sides of the sensor support plate are provided with the retractable elastic frame; the retractable elastic frame comprises four M-shaped frames and four W-shaped frames, the four M-shaped frames are sequentially connected in a head-to-tail manner to form a first hollow ring, the four W-shaped frames are sequentially connected in a head-to-tail manner to form a second hollow ring, and the first hollow ring and the second hollow ring are concentrically connected; the four M-shaped frames have four first joint points in sequence, the four W-shaped frames have four second joint points in sequence, and the first joint points and the second joint points are connected in correspondence; the number of the sensor support plates is four and they are distributed in a ring shape at equal intervals.

[0014] Compared with the prior art, the present disclosure has the following technical effects:

[0015] The blood pressure monitoring system integrates the pressure and flow rate measuring modules on the same base, improves the system integration, reduces the number of implanted monitors, and provides more comprehensive monitoring data for doctors. The first pressure sensitive diaphragm and the second pressure sensitive diaphragm in the pressure sensor have the same structure and the same arrangement, the upper and lower sides of the second pressure sensitive diaphragm are in communication with the fluid space, and the second pressure sensitive diaphragm is in a stress-free state, which can compensate for the resistance drift caused by temperature and further improve the pressure detection accuracy.

[0016] It should be understood that the content described in the summary section is not intended to limit the key or important features of the embodiments of the present disclosure, nor to limit the scope of the present disclosure. Other features of the present disclosure will become apparent through the following description. BRIEF DESCRIPTION OF DRAWINGS

[0017] The above and other features, advantages, and aspects of embodiments of the present disclosure will become more apparent by describing in detail the following embodiments with reference to the attached drawings. The drawings are intended to better understand the present disclosure and do not limit the present disclosure. In the drawings, the same or similar reference numerals refer to the same or similar elements, and:

[0018] Figure 1 A high-precision implantable blood pressure monitoring system is provided for an embodiment of the present disclosure, and a structure diagram of a pressure sensor in the system is shown;

[0019] Figure 2 An exploded view of a pressure sensor in a high-precision implantable blood pressure monitoring system according to an embodiment of this disclosure;

[0020] Figure 3 A cross-sectional schematic diagram of a pressure sensor in a high-precision implantable blood pressure monitoring system provided in an embodiment of this disclosure;

[0021] Figure 4 This is a schematic diagram of the main body of a pressure sensor in a high-precision implantable blood pressure monitoring system according to an embodiment of the present disclosure, wherein 1 in the figure is the main body of the pressure sensor;

[0022] Figure 5 This is a schematic diagram of the structure of a pressure sensor diaphragm in a high-precision implantable blood pressure monitoring system according to an embodiment of the present disclosure, wherein 2 and 3 are the first or second pressure sensor diaphragms;

[0023] Figure 6 This is a schematic diagram of the flow velocity detection module in a pressure sensor of a high-precision implantable blood pressure monitoring system according to an embodiment of the present disclosure;

[0024] Figure 7 This is a schematic diagram of the assembly of a pressure sensor and a sensor bracket in a high-precision implantable blood pressure monitoring system according to an embodiment of this disclosure. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of the embodiments of this disclosure clearer, the technical solutions of the embodiments of this disclosure will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this disclosure, and not all embodiments. Based on the embodiments of this disclosure, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this disclosure.

[0026] Furthermore, the term "and / or" in this article is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. Additionally, the character " / " in this article generally indicates that the preceding and following related objects have an "or" relationship.

[0027] like Figures 1 to 7 As shown, one embodiment of this disclosure provides a high-precision implantable blood pressure monitoring system, including: a pressure sensor, a wireless transmission module, and a sensor bracket; the pressure sensor is disposed on the sensor bracket and fixed to the inside of a blood vessel by the sensor bracket; the wireless transmission module is connected to the pressure sensor and is used to receive and transmit monitoring data externally;

[0028] The pressure sensor comprises a main body 1, a first pressure sensing diaphragm 2 and a second pressure sensing diaphragm 3; the main body 1 comprises a base 11, a first pressure sensing groove 12, a second pressure sensing groove 13 and a rectangular through hole 14; the base 11 is a rectangular solid; the first pressure sensing groove 12 and the second pressure sensing groove 13 are both circular grooves with the same radial dimension, and the first pressure sensing groove 12 and the second pressure sensing groove 13 are both arranged on the top surface of the base 11 and arranged side by side along the long direction of the top surface of the base 11; the rectangular through hole 14 is arranged on the side surface of the base 11, and the extension direction of the rectangular through hole 14 is parallel to the short direction of the base 11; the rectangular through hole 14 is located at the bottom of the second pressure sensing groove 13 and communicates with the second pressure sensing groove 13; the first pressure sensing diaphragm 2 and the second pressure sensing diaphragm 3 are both circular diaphragms with the same size, and the first pressure sensing diaphragm 2 is sealingly arranged on the top of the first pressure sensing groove 12, and the second pressure sensing diaphragm 3 is sealingly arranged on the top of the second pressure sensing groove 13.

[0029] Optionally, the top of the first pressure sensing groove 12 and the top of the second pressure sensing groove 13 are both provided with a limiting groove, and the limiting groove is matched with the size of the first pressure sensing diaphragm 2 and the second pressure sensing diaphragm 3.

[0030] Optionally, the first pressure sensing diaphragm 2 and the second pressure sensing diaphragm 3 both comprise an elastic diaphragm 5 and a pressure sensing resistor 6; the pressure sensing resistor 6 is arranged on the surface of the elastic diaphragm 5; the pressure sensing resistor 6 is composed of a plurality of bending parts in series, and the shape of the bending part is Π-shaped; the elastic diaphragm 5 is divided into four regions of upper, lower, left and right, wherein the upper part and the lower part are both provided with three bending parts, the left part is provided with three bending parts, and the right part is provided with two bending parts; the lead-in end and the lead-out end of the pressure sensing resistor 6 are respectively connected with the two bending parts arranged in the right part; the bending parts of the upper and lower regions respectively extend along the vertical direction of the elastic diaphragm 5, and the bending parts of the left and right regions respectively extend along the horizontal direction of the elastic diaphragm 5; the bending parts of the upper part and the lower part are perpendicular to the bending parts of the left part and the right part.

[0031] Optionally, a limiting column 15 is arranged in the first pressure sensing groove 12, and the limiting column 15 is used to prevent the deformation of the first pressure sensing diaphragm 2 from exceeding the range.

[0032] Optionally, the pressure sensor further comprises a flow rate detection module 4, the flow rate detection module 4 comprising a humanoid elastic sheet 41, a rectangular support body 42, a strain resistance 43 and a circular through hole 44; the rectangular support body 42 is a rectangular hollow body and its left and right ends are through, the upper and lower sides of the rectangular support body 42 are both provided with a through hole (the circular through hole 44) (the external fluid is communicated with the second pressure sensing groove 13 through the through hole of the flow rate detection module 4); the left and right sides of the rectangular support body 42 are both provided with the humanoid elastic sheet 41, and the humanoid elastic sheet 41 is provided with the strain resistance 43.

[0033] Optionally, the size of the rectangular support body 42 matches the size of the rectangular through hole 14, and the rectangular support body 42 is arranged inside the rectangular through hole 14.

[0034] Optionally, the strain resistance 43 is composed of a plurality of bending parts in series; the humanoid elastic sheet 41 comprises two bending parts and a vertical part, and the bending parts of the strain resistance 43 are arranged at the junctions of the bending parts and the vertical part of the humanoid elastic sheet 41; the side surface of the rectangular support body 42 is provided with a communication groove, and a wire is arranged in the communication groove for connecting the strain resistances 43 in the humanoid elastic sheets 41 on the left and right sides of the rectangular support body 42 in series.

[0035] Optionally, the top surface of the base 11 is provided with a plurality of terminal blocks, and the pressure sensing resistors 6 on the first pressure sensing diaphragm 2 and the second pressure sensing diaphragm 3 and the strain resistors 43 on the humanoid elastic sheet 41 are respectively connected to the corresponding terminal blocks and connected to the wireless transmission module through the terminal blocks.

[0036] Optionally, the wireless transmission module is arranged on the sensor support or between the subcutaneous fat layer and the dermis layer; the wireless transmission module is integrated with a receiving coil, a processing module, a power supply circuit, an energy storage module, a signal transmitting module and the like to obtain energy from an external device in a wireless manner and supply power to the sensor.

[0037] Optionally, the sensor support comprises a sensor support plate 7 and a retractable elastic frame 8; the sensor support plate 7 and the retractable elastic frame 8 are integrally formed (such as laser cutting); the two sides of the sensor support plate 7 are both provided with the retractable elastic frame 8; the retractable elastic frame 8 comprises four M-shaped frames and four W-shaped frames, the four M-shaped frames are sequentially connected end to end to form a first hollow ring, the four W-shaped frames are sequentially connected end to end to form a second hollow ring, and the first hollow ring and the second hollow ring are concentrically connected; the four M-shaped frames sequentially have four first junction points, the four W-shaped frames sequentially have four second junction points, and the first junction points and the second junction points are correspondingly connected; the number of the sensor support plate 7 is four and is distributed in a ring shape at equal intervals.

[0038] Optionally, the sensor support plate 7 is provided with a mounting groove matching the size of the pressure sensor.

[0039] Optionally, the base 11 is made of Si, SiO2, ceramic, inert metal, etc., and is prepared by sputtering, evaporation, photolithography, etching, etc.

[0040] Optionally, the pressure sensor is manufactured by MEMS technology.

[0041] Optionally, the pressure sensing resistor 6 and the strain resistor 43 have a larger resistance when they produce tensile deformation.

[0042] Optionally, the pressure sensing resistor 6 and the strain resistor 43 are provided with a waterproof coating layer of silicone, polyimide, etc.

[0043] Optionally, the sensor support is made of stainless steel, cobalt-chromium alloy, titanium alloy, etc., and can be curled into a radially compressed state and expanded in the patient's body by an expandable balloon or the like.

[0044] Working principle of high-precision implantable blood pressure monitoring system:

[0045] 1. Pressure measurement: the first pressure sensing diaphragm 2 senses the fluid pressure and converts it into resistance change, and the data is collected and transmitted by the wireless transmission module. The first pressure sensing diaphragm 2 and the second pressure sensing diaphragm 3 have the same structure and arrangement, and the second pressure sensing diaphragm 3 is in communication with the fluid space on both sides, which is in a stress-free state and can compensate for the resistance drift caused by temperature. In addition, temperature measurement can also be achieved by the resistance change of the pressure sensing resistor 6 on the second pressure sensing diaphragm 3.

[0046] 2. Flow rate measurement: when the fluid acts on the human-shaped elastic sheet 41, it will cause the human-shaped elastic sheet 41 to deform (both the vertical part and the curved part will produce certain bending), at this time the resistance change of the strain resistor 43 will convert the fluid speed information into resistance change, and the data is collected and transmitted by the wireless transmission module.

[0047] The external terminal device collects and analyzes data through the wireless transceiver module to realize the monitoring of blood pressure, flow rate, etc.

[0048] It should be noted that, for the foregoing method embodiments, in order to simply describe, they are all described as a series of action combinations, but those skilled in the art should know that the disclosure is not limited by the action sequence described, because according to the disclosure, certain steps can be performed in other sequences or simultaneously. Secondly, those skilled in the art should know that the embodiments described in the specification are all optional embodiments, and the actions and modules involved are not necessarily required by the disclosure.

[0049] Those skilled in the art can clearly understand that, for the convenience and brevity of description, the working process of the device involved in the relevant steps of the method can refer to the corresponding process in the foregoing device embodiments, which will not be repeated here.

[0050] It should be understood that the steps can be reordered, added or deleted using the various forms of flow shown above. For example, each step described in the present disclosure can be executed in parallel, sequentially or in a different order, as long as the desired results of the technical solutions of the present disclosure can be achieved, which is not limited herein.

[0051] The foregoing detailed description does not constitute a limitation on the protection scope of the present disclosure. Those skilled in the art should understand that various modifications, combinations, sub-combinations and substitutions can be made according to design requirements and other factors. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present disclosure shall be included in the protection scope of the present disclosure.

Claims

1. A high-precision implantable blood pressure monitoring system, characterized in that, The utility model relates to a kind of blood vessel pressure sensor, including: pressure sensor, wireless transmission module, sensor support;The pressure sensor is arranged on the sensor support, is fixed to inside of blood vessel by the sensor support;The wireless transmission module is connected with the pressure sensor, for receiving and transmitting monitoring data outward; The pressure sensor includes main body, first pressure diaphragm and second pressure diaphragm;The main body includes pedestal, first pressure groove, second pressure groove and rectangular through-hole;The pedestal is rectangular entity;The first pressure groove and the second pressure groove are both circular grooves with same radial dimension, and the first pressure groove and the second pressure groove are both arranged on the top surface of the pedestal and arranged in parallel along the long side direction of the top surface of the pedestal;The side surface of the pedestal is provided with the rectangular through-hole, and the extension direction of the rectangular through-hole is parallel to the short side direction of the pedestal;The rectangular through-hole is located at the bottom of the second pressure groove and communicates with it;The first pressure diaphragm and the second pressure diaphragm are both circular thin sheets with same dimension, and the first pressure diaphragm is sealingly arranged at the top of the first pressure groove, and the second pressure diaphragm is sealingly arranged at the top of the second pressure groove; The pressure sensor further includes flow rate detection module, and the flow rate detection module includes humanoid elastic sheet, rectangular support, strain resistance and circular through-hole;The rectangular support is a rectangular hollow body with both ends penetrating, and the upper and lower sides of the rectangular support are both provided with perforations;The left and right sides of the rectangular support are both provided with the humanoid elastic sheet, and the strain resistance is arranged on the humanoid elastic sheet;The rectangular support is arranged in the interior of the circular through-hole. Wherein, 2. The high accuracy implantable blood pressure monitoring system of claim 1, wherein, The first pressure diaphragm and the second pressure diaphragm both include elastic diaphragm and pressure sensing resistor;The pressure sensing resistor is arranged on the surface of the elastic diaphragm;The pressure sensing resistor is composed of multiple bending parts in series, and the shape of the bending part is Π-shaped;The elastic diaphragm is divided into four regions of upper, lower, left and right, wherein three bending parts are arranged in the upper and lower parts, three bending parts are arranged in the left part, and two bending parts are arranged in the right part, and the lead-in end and the lead-out end of the pressure sensing resistor are connected with the two bending parts arranged in the right part;The bending parts of the upper and lower regions extend along the vertical direction of the elastic diaphragm respectively, the bending parts of the left and right regions extend along the horizontal direction of the elastic diaphragm respectively, and the bending parts of the upper and lower regions are perpendicular to the bending parts of the left and right regions. Wherein, 3. The high accuracy implantable blood pressure monitoring system of claim 1, wherein, The size of the rectangular support matches the size of the rectangular through-hole. Wherein, 4. The high accuracy implantable blood pressure monitoring system of claim 3, wherein, The strain resistance is composed of multiple bending parts in series;The humanoid elastic sheet includes two bending parts and a vertical part, and the bending part of the strain resistance is arranged at the intersection of the bending part and the vertical part of the humanoid elastic sheet;The side surface of the rectangular support is provided with a communication groove, and a wire is arranged in the communication groove for connecting the strain resistances in the humanoid elastic sheets on the left and right sides of the rectangular support in series. Wherein, 5. The high accuracy implantable blood pressure monitoring system of claim 2 or 4, wherein, ​ The top surface of the base is provided with a plurality of terminal blocks, the pressure sensing resistors on the first and second pressure sensing diaphragms and the strain resistors on the human-shaped elastic sheet are respectively connected to corresponding terminal blocks, and are connected to the wireless transmission module through the terminal blocks.

6. The high accuracy implantable blood pressure monitoring system of claim 1, wherein, Wherein, The wireless transmission module is arranged on the sensor support or between the subcutaneous fat layer and the dermis layer; the wireless transmission module is integrated with a receiving coil, a processing module, a power supply circuit, an energy storage module and a signal transmitting module.

7. The high accuracy implantable blood pressure monitoring system of claim 1, wherein, Wherein, The sensor support comprises a sensor support plate and a retractable elastic frame; the sensor support plate and the retractable elastic frame are integrally formed; the two sides of the sensor support plate are provided with the retractable elastic frame; the retractable elastic frame comprises four M-shaped frames and four W-shaped frames, the four M-shaped frames are sequentially connected in a head-to-tail manner to form a first hollow ring, the four W-shaped frames are sequentially connected in a head-to-tail manner to form a second hollow ring, and the first hollow ring and the second hollow ring are connected in a concentric manner; the four M-shaped frames have four first joint points in sequence, the four W-shaped frames have four second joint points in sequence, and the first joint points and the second joint points are connected in correspondence; the number of the sensor support plates is four and they are distributed in a ring shape at equal intervals.

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