Special multi-color safe hair dyeing cream for men and preparation method thereof

Abstract

The invention provides a special multi-color safe hair dyeing cream for men and a preparation method thereof. The special multi-color safe hair dyeing cream for men is composed of an agent A serving as a dye matrix and an agent B serving as an oxidizing agent, wherein the mass ratio of the agent A to the agent B is 1: (1-1.5); wherein every 100 parts by weight of the agent A comprises the following components: 0.6 to 3.0 parts of a dye precursor, 0.5 to 5.0 parts of a natural pigment, 3.0 to 8.0 parts of a soothing agent, 3.0 to 7.0 parts of an alkalizer, 0.5 to 2.0 parts of a thickening agent, 1.0 to 3.0 parts of hair care oil and the balance of deionized water; every 100 parts by weight of the agent B comprises the following components: 3.0-10.0 parts of hydrogen peroxide, 0.1-0.5 part of phosphoric acid, 0.5-1.5 parts of an emulsifier, 0.1-0.3 part of disodium ethylene diamine tetraacetate and the balance of deionized water, and the pH value of the agent B is 2.5-3.5. Besides, a temperature-sensitive film-forming agent (polyethylene glycol-60 hydrogenated castor oil and hydroxypropyl methyl cellulose), lactic streptococci peptide and trehalose are creatively added according to a special hair dyeing scene for men, and the special hair dyeing cream which is suitable for rough and hard hair of men, safe, reliable and lasting in dyeing effect is provided.

Description

Technical Field

[0001] This invention belongs to the technical field of hair dyeing products, specifically relating to a safe multi-color hair dye for men and its preparation method. Background Technology

[0002] With the rapid development of the men's grooming market, more and more men are using hair dye to cover up gray hair and improve their image. However, there are still many core problems with hair dye products on the market that are difficult to solve, which seriously affect the user experience and health and safety.

[0003] First, the risks of carcinogenicity and sensitization remain high. Most permanent hair dyes rely on aromatic compounds such as phenylenediamines (e.g., p-phenylenediamine PPD) and resorcinol as core dye precursors to achieve long-lasting color. These ingredients have been classified as Group 2B carcinogens by the International Agency for Research on Cancer and are prone to triggering scalp immune responses, leading to redness, itching, and even allergic dermatitis. Men, in particular, have 1.5-2 times more sebum secretion on their scalps than women, and this sebum accelerates the penetration of chemical components, making the probability of sensitization more than 30% higher. Simultaneously, traditional products often add highly volatile ammonia as an alkalizing agent to open the hair cuticle and promote dye absorption. The pungent odor not only irritates the respiratory tract but also damages the scalp barrier, leading to dry, frizzy hair and increased breakage.

[0004] Secondly, there is a serious lack of products specifically designed for men. Most existing multi-color hair dyes are designed around female aesthetics, focusing on bright and intense colors. However, men tend to prefer natural black, understated brown, and soft golden brown tones that closely resemble their natural hair texture. The few products on the market that claim to be "specifically for men" simply adjust the color depth without being optimized for men's hair type and usage scenarios. For example, men often have short hair, and the hairline, behind the ears, and temples have a large exposed skin area when dyeing, making it easy for the dye to stain the skin. Residual pigment requires repeated washing with makeup remover, which is both troublesome and can easily aggravate scalp irritation. Furthermore, men's hair is coarser and harder, with a denser cuticle structure. Traditional formulas either have difficulty coloring, requiring extended processing time of over 40 minutes, or increase the concentration of chemical dyes to improve the coloring effect, resulting in a hard, artificial color that lacks natural texture.

[0005] In addition, some brands have launched "plant-based hair dyes" to avoid the risk of cancer, but most of them rely on a single plant extract (such as arborvitae leaf) as the pigment source. Not only is the color light, but it also fades significantly after only 1-2 weeks. Multiple applications are required to achieve the desired color, making the process cumbersome. On the other hand, products that pursue long-lasting color will revert to traditional chemical formulas, falling into the dilemma of "safe but ineffective, effective but unsafe".

[0006] Finally, when the room temperature is below 15℃ in winter, hydrogen peroxide is prone to slow coloring and large color difference due to decreased activity. Current technology can only suggest that users use a heating cap to assist, which is inconvenient and increases the risk of hair damage.

[0007] In summary, addressing the common problems of existing hair dyes, this paper proposes a safe, reliable, and long-lasting men's hair dye suitable for men with coarse and stiff hair, which has broad market prospects. Summary of the Invention

[0008] The purpose of this invention is to provide a safe multi-color hair dye for men, which is composed of agent A as a dye matrix and agent B as an oxidizing agent, with the mass ratio of agent A to agent B being 1:(1-1.5).

[0009] Each 100 parts by weight of Agent A includes the following components: 0.6-3.0 parts of dye precursor, 0.5-5.0 parts of natural pigment, 3.0-8.0 parts of soothing agent, 3.0-7.0 parts of alkalizing agent, 0.5-2.0 parts of thickener, 1.0-3.0 parts of hair oil, and the balance being deionized water;

[0010] Each 100 parts by weight of Agent B comprises the following components: 3.0-10.0 parts hydrogen peroxide, 0.1-0.5 parts phosphoric acid, 0.5-1.5 parts emulsifier, 0.1-0.3 parts disodium ethylenediaminetetraacetate, with the balance being deionized water. The pH value of Agent B is 2.5-3.5.

[0011] In a preferred embodiment, in agent A, the dye precursor is composed of 2,4-diaminoethoxyphenyl sulfate and 4-aminom-cresol in a mass ratio of 1:(0.02-1.25).

[0012] In a preferred embodiment, in agent A, the alkalizing agent is at least one selected from monoethanolamine, diethanolamine, and triethanolamine.

[0013] In a preferred embodiment, in Agent A, the natural pigment is selected from at least one of henna extract, gallnut extract, walnut shell extract, and curcumin.

[0014] In a preferred embodiment, in Agent A, the soothing agent is a compound of panthenol, ceramide, and centella asiatica extract in a mass ratio of 1:(0.1-3):(0.2-4).

[0015] In a preferred embodiment, in agent A, the thickener includes one or more of hydroxyethyl cellulose, hydroxypropyl methylcellulose, carbomer, xanthan gum, and guar gum.

[0016] In a preferred embodiment, in Agent A, the hair oil includes one or more of jojoba oil, lanolin, olive oil, caprylic / capric triglyceride, and coconut oil.

[0017] In a preferred embodiment, for coarse and stiff hair, agent A further includes 0.3-0.8 parts of nisin.

[0018] In a preferred embodiment, agent A further comprises 0.5-2.0 parts of a thermosensitive film-forming agent; the thermosensitive film-forming agent is a compound of polyethylene glycol-60 hydrogenated castor oil and hydroxypropyl methylcellulose in a mass ratio of 1:(1-1.5).

[0019] In a preferred embodiment, in agent B, the emulsifier includes one or more of Tween-80, Span-60, cetearyl alcohol polyether-20, lauryl alcohol polyether-4, and polyglycerol-3 distearate.

[0020] In a preferred embodiment, agent B further includes 0.1-0.3 parts of trehalose; the mass ratio of trehalose to disodium EDTA is 1:(0.5-1).

[0021] In a preferred embodiment, the formulations of agent A and agent B in different color schemes specifically include, for men's preferred color schemes:

[0022] Black version: Each 100 parts by weight of Agent A includes 1.3-1.7 parts of 2,4-diaminoethoxybenzene sulfate, 0.05-0.15 parts of 4-aminom-cresol, 2.5-4.0 parts of henna extract, and 0.3-0.7 parts of gallnut extract; each 100 parts by weight of Agent B includes 3.0-5.0 parts of hydrogen peroxide.

[0023] Natural Brown: Every 100 parts by weight of Agent A includes 0.8-1.2 parts of 2,4-diaminoethoxybenzene sulfate, 0.7-0.9 parts of 4-aminom-cresol, and 1.0-2.0 parts of walnut shell extract; every 100 parts by weight of Agent B includes 5.0-7.0 parts of hydrogen peroxide.

[0024] Golden Brown Formula: Every 100 parts by weight of Agent A includes 0.5-0.7 parts of 2,4-diaminoethoxybenzene sulfate, 0.2-0.4 parts of 4-aminom-cresol, and 0.1-0.3 parts of curcumin; every 100 parts by weight of Agent B includes 8.0-10.0 parts of hydrogen peroxide.

[0025] Another object of the present invention is to provide a method for preparing a multi-color safe hair dye for men, comprising the following steps:

[0026] Preparation of Agent A: ① Heat deionized water to 40-50℃, add alkalizing agent and stir until completely dissolved; ② Add thickener and homogenize at 3000-5000r / min for 5-8 minutes to form a paste base; ③ Cool to 35-40℃, add dye precursor and stir for 3-5 minutes; ④ If for coarse and stiff hair, add nisin and stir for 5 minutes; ⑤ Add natural pigment, soothing agent, and hair oil; if it contains temperature-sensitive film-forming agent, add it in this step and stir for 20-30 minutes; ⑥ Test the pH value to 8.5-9.5, and after passing the test, defoam and fill.

[0027] Preparation of Agent B: ① Add phosphoric acid to deionized water and stir at room temperature until the pH value stabilizes at 2.5-3.5; ② Slowly add hydrogen peroxide dropwise at a rate of 1-2 mL / s while stirring at 1000-2500 r / min; ③ Add emulsifier and EDTA-2Na; if trehalose is present, add it in this step and stir for 15-20 minutes; ④ Fill in the container away from light.

[0028] Another object of the present invention is to provide a method of using a multi-color safe hair dye for men, comprising the following steps:

[0029] A method of using a men's multi-color safe hair dye as described in any one of claims 1-9, characterized by comprising the following steps:

[0030] S1 determines the mixing ratio of agent A and agent B according to the color scheme, with the black and natural brown versions at a ratio of 1:1 and the golden brown version at a ratio of 1:1.5.

[0031] S2 Mix agent A and agent B for 1-2 minutes until a uniform paste is formed. Apply the paste to the hair roots first, and after 5 minutes, apply it to the mid-lengths and ends of the hair to ensure even coverage.

[0032] The resting time for S3 is controlled according to the color scheme. In an environment of 10-35℃, the black version should be rested for 20-40 minutes, the natural brown version for 25-40 minutes, and the golden brown version for 30-45 minutes.

[0033] Rinse S4 with warm water at 38-40℃ until no residue remains, then condition and air dry.

[0034] Compared with the prior art, the technical solution of the present invention has the following advantages:

[0035] 1. This invention creatively integrates low-sensitivity chemical dye precursors with natural pigments and ammonia-free alkalizing agents into a systematic design. Specifically, 2,4-diaminoethoxybenzene sulfate and 4-aminom-cresol are compounded at a ratio of 1:(0.03-1.13), avoiding carcinogenic and sensitizing components such as PPD and resorcinol, while precisely adapting to the color development needs of men in black, brown, and golden brown through a gradient ratio. Combined with natural pigments such as henna and walnut shells, it solves the problem of harsh color development often caused by traditional low-sensitivity dyes. Furthermore, ethanolamine or MEA-ethanolamine complexes are used to replace ammonia, reducing respiratory irritation and allowing for adjustment of the degree of cuticle opening according to the color scheme. After testing, colorfastness reaches 4-5 weeks, with a scalp irritation rate of only 1-2%, completely breaking the existing industry dilemma of safe dyes resulting in color discrepancies and effective dyes causing sensitization.

[0036] 2. Regarding the design tailored for men's specific scenarios, this invention creatively incorporates a temperature-sensitive film-forming agent (polyethylene glycol-60 hydrogenated castor oil + hydroxypropyl methylcellulose). Utilizing its properties of forming a film at body temperature and dissolving in warm water, it effectively prevents color smudging along the hairline when dyeing short men's hair, eliminating the need for manual application of petroleum jelly. Furthermore, addressing the issue of coarse and stiff men's hair, this invention creatively incorporates nisin, a natural antibacterial agent primarily used in food preservation. During experimental design, the inventors discovered that nisin can gently open the gaps between hair cuticles, reducing the coloring time from 40 minutes to 25 minutes without damaging the hair structure. Even further, this invention creatively combines trehalose with EDTA-2Na, effectively solving the problem of decreased hydrogen peroxide activity at low winter temperatures, allowing for even coloring without a heating cap at 10-15℃.

[0037] 3. In this invention, Agent A, as the dye matrix, and Agent B, as the oxidant, also produce a synergistic effect: the temperature-sensitive film-forming agent, while preventing dye from sticking to the skin, does not affect the dye penetration function of nisin lactate. The synergistic effect of the two can simultaneously achieve the technical effects of preventing skin contact and rapid coloring; the low-temperature stability of trehalose can work with the golden brown bleaching system to achieve safe color development, and the addition of soothing ingredients such as panthenol and ceramides provides a good repair effect on hair damage after bleaching. Furthermore, this invention designs specific combinations of dye ratios, pigment types, and oxidant concentrations to precisely meet men's preferences for natural and understated hair colors, achieving a user satisfaction rate of over 95%. Detailed Implementation

[0038] To enable those skilled in the art to better understand the present invention, the present invention will be further described in detail below with reference to specific embodiments. However, it should be understood that the scope of protection of the present invention is not limited to the specific embodiments. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0039] Unless otherwise specified, the technical means used in this invention are conventional means well known to those skilled in the art. All raw materials, reagents, instruments, and equipment used in this invention can be purchased commercially or prepared using existing methods. Unless otherwise specified, all reagents used in this invention are of analytical grade.

[0040] In this invention, the weight parts can be weight units known in the art such as μg, mg, g, kg, or multiples thereof, such as 1 / 10, 1 / 100, 10 times, 100 times, etc.

[0041] The testing methods used in the embodiments of the present invention include:

[0042] I. Scalp Stimulation Rate Test

[0043] (a) Sample selection: For each example / comparative group, 10 healthy male volunteers aged 25-45 years were selected, including 5 people with mildly sensitive scalps. The characteristics of this group of people with mildly sensitive scalps are that they have no history of serious hair dye allergies, but have experienced mild scalp tightness.

[0044] (II) Application and Observation: Volunteers wore disposable gloves and used a hair dye comb to accurately take 2g of hair dye, applying it evenly to a specific 2cm x 2cm area of ​​scalp below the ear, taking special care to avoid broken skin. After application, the area was covered with breathable gauze and secured to ensure the hair dye could act stably on the test area and to avoid interference from external factors.

[0045] (III) Application and Cleaning: Let stand for 30 minutes to allow the hair dye to fully work. After the application is complete, rinse the test area with running warm water at a constant temperature of 38℃ until clean, then gently pat dry with a clean towel.

[0046] (IV) Scoring Criteria: At two key time points, 24 hours and 48 hours after rinsing, the scalp condition was carefully observed and scored according to specific scoring criteria. The scoring criteria are as follows: no reaction is scored as 0 points; slight redness is scored as 1 point; obvious redness and swelling is scored as 2 points; if redness and swelling are accompanied by itching, it is scored as 3 points; severe cases of redness, swelling, itching, and oozing are scored as 4 points. The stimulation rate is calculated by determining the percentage of volunteers with a score ≥2 out of the total number of volunteers, i.e., stimulation rate = (number of volunteers with a score ≥2 / total number of volunteers) × 100%.

[0047] II. 24-hour skin sensitization test

[0048] (I) Sample Preparation: Accurately weigh 0.1g of the prepared hair dye and mix it thoroughly with medical petroleum jelly in a 1:1 ratio to prepare the test sample. This mixing method simulates the actual contact between the product and scalp oil during hair dyeing, and can more realistically test the possibility of skin sensitization caused by the hair dye in real-world usage scenarios. Because scalp oil affects the interaction between the hair dye and the skin, simulating this environment makes the test results more practically meaningful.

[0049] (II) Patch Test: Five hairless areas, each 1cm × 1cm in size, were selected on the inner side of the volunteer's upper arm. Different substances were applied to each of these five areas. The test substance, blank petroleum jelly (as a negative control to compare and determine whether the test substance would induce an additional allergic reaction), and 0.1% p-phenylenediamine solution (as a positive control to verify the effectiveness of the test system; if the positive control area did not show the expected allergic reaction, it indicates a problem with the test) were applied to each area. After application, hypoallergenic tape was used to fix the patch in place to prevent displacement and ensure the test results.

[0050] (III) Observation and Judgment: After 24 hours of continuous application, the patch was carefully removed, and volunteers were allowed to rest for 30 minutes to allow their skin condition to stabilize. The applied area was then scored according to specific criteria: 0 points for no erythema; 1 point for mild erythema; 2 points for moderate erythema; and 3 points for severe erythema accompanied by edema. The sensitization rate was calculated as (number of volunteers with a test substance area score ≥2 points and higher than the negative control / total number of volunteers) × 100%.

[0051] III. Coloring Time and Uniformity Test

[0052] (a) Hair sample preparation: Select coarse and stiff hair samples that are suitable for the example / comparative example. The definition of coarse and stiff hair is a diameter > 0.08 mm. Cut the selected hair into hair bundles with a length of 10 cm and a weight of 2 g, then wash them carefully with shampoo to remove oil, dirt and other impurities from the hair surface. After washing, let them air dry to obtain clean blank samples.

[0053] (II) Dyeing Procedure: Accurately weigh 1g of hair dye and apply it evenly to every part of the hair strand. After application, place the hair strand in a constant temperature and humidity chamber. The chamber environment is set according to the test scenario. When testing the effect at room temperature, the temperature is controlled at 25℃±2℃ and the humidity is maintained at 50%±5%; when testing the effect at low temperature, the temperature is adjusted to 12℃±2℃ and the humidity is also maintained at 50%±5%.

[0054] (III) Determining the Coloring Time: Every 5 minutes, remove one strand of hair from the temperature and humidity control chamber, gently rinse with warm water, dry, and then compare it with the target color chart. The target color chart has a clear correspondence for different hair dye colors, such as black corresponding to Pantone 19-4001TPX, and golden brown corresponding to Pantone 14-0940TPX, etc. The coloring time is defined as the time when the hair strand first reaches 90% similarity to the target color chart.

[0055] (iv) Uniformity Scoring: After dyeing, a colorimeter (model: Minolta CR-400) is used to measure the Lab values ​​at three key points: the roots, mid-lengths, and ends of the hair strand. In the Lab value, L represents lightness, a represents red-green hue, and b represents yellow-blue hue. By measuring the Lab values ​​at these three points, the ΔE value (color difference) between the three points is calculated, and uniformity is scored based on the ΔE value. The scoring criteria are as follows: ΔE < 0.5 is scored as 90 points, indicating extremely uniformity; 0.5 ≤ ΔE < 1.0 is scored as 80 points, indicating uniformity; 1.0 ≤ ΔE < 2.0 is scored as 65 points, indicating relatively uniformity; and ΔE ≥ 2.0 is scored as 50 points, indicating non-uniformity.

[0056] IV. Hairline staining rate test (artificial scalp carrier)

[0057] (I) Preparation of Artificial Scalp Samples: A simulated artificial scalp made of silicone rubber was selected. This artificial scalp has a standard hairline structure and an area ≥ 5cm × 5cm. First, the surface of the artificial scalp was gently rinsed with deionized water to remove any impurities. Then, it was placed in a 60℃ oven to dry for 30 minutes. After cooling, its initial mass was accurately weighed using an electronic balance with an accuracy of 0.001g and recorded as m0. At the same time, the hairline test area was marked on the artificial scalp using white graph paper, defining a rectangular area of ​​2cm × 3cm. This area covered typical positions of the forehead and temples. After marking, a photograph of the initial unstained state was taken using a digital camera (fixed parameters: distance 10cm, white light source, resolution 300dpi) and archived as a baseline for subsequent comparison.

[0058] (II) Dyeing and Setting Procedure: Accurately weigh 0.5g of the mixed hair dye using an electronic balance and place it on a 1cm wide hair dye brush. Apply the dye parallel to the marked hairline test area. During application, strictly control the application pressure by suspending a 50g weight on the brush handle to ensure that the dye evenly covers the test area without accumulation. After application, place the artificial scalp in a constant temperature and humidity chamber (temperature 25℃±2℃, humidity 50%±5%) and set it for the coloring time set by the hair dye.

[0059] (III) Collection of Stain Residue: After settling, use a pre-weighed (m2) dry medical absorbent cotton ball to hold the test area on tweezers, apply 50g pressure, and wipe the area three times in the same direction. Collect the absorbent cotton ball. Then, take a new medical absorbent cotton ball, soak it in 0.5mL of 95% anhydrous ethanol, and wipe the test area three times in the same direction. Collect the absorbent cotton ball from the second wiping. Place both collected absorbent cotton balls together in a 60℃ oven and dry for 30 minutes to remove ethanol and moisture. After cooling, weigh the total mass again and record it as m1.

[0060] (iv) Calculation of Stain Rate: The formula for calculating the hairline stain rate (%) is (m1-m2) / initial applied hair dye mass × 100, where the initial applied hair dye mass is 0.5g. The stain rate is graded as follows: when the stain rate is <5%, it is rated as excellent, indicating good skin-protecting effect; when 5% ≤ stain rate <15%, it is rated as good; when 15% ≤ stain rate <25%, it is rated as average; and when the stain rate is ≥25%, it is rated as poor.

[0061] V. Colorfastness Test

[0062] (a) Preparation of dyed samples: Prepare dyed hair strands according to the above-mentioned method of "coloring time test". After preparation, dry the hair strands as samples for color fastness test.

[0063] (II) Shampooing Procedure: The test sample was fixed on the shampooing device, and the hair strands were rinsed and rubbed with a 0.2% sodium lauryl sulfate solution (which simulates shampoo ingredients) at a temperature of 38℃±2℃. The specific procedure was to rub for 1 minute each time, followed by rinsing for 1 minute, and to perform the procedure 3 times a week to simulate the daily shampooing frequency.

[0064] (III) Calculation of fading rate: The L value of the samples was measured using a colorimeter at three time points: before shampooing (referred to as week 0), 2 weeks after shampooing, and 4 weeks after shampooing. (The L value represents lightness; the higher the lightness, the more obvious the fading.) The formula for calculating the fading rate is (4-week L value - 0-week L value) / 0-week L value × 100%. The smaller this value, the better the colorfastness.

[0065] VI. Hydrogen peroxide activity retention rate test

[0066] (I) Sample preparation: Accurately weigh 10g of Agent B for both the Example (containing trehalose) and the Comparative Example (without trehalose), and place them in a constant temperature incubator at 12℃±2℃ for 24 hours.

[0067] (II) Titration Procedure: Remove the sample from the incubator and add 5 mL of sulfuric acid solution (1:5) to the sample for acidification. Then add 2 mL of potassium iodide solution (10%) and react the mixture in the dark for 10 minutes. After the reaction, titrate with 0.02 mol / L sodium thiosulfate standard solution until the solution turns pale yellow. At this point, add 1 mL of starch indicator and continue titrating until the blue color disappears. Record the volume of sodium thiosulfate standard solution consumed as V1. Simultaneously, take fresh reagent B (not subjected to low-temperature storage) and titrate it using the same method, recording the volume consumed as V0.

[0068] (III) Calculation of Activity Retention Rate: The formula for calculating the activity retention rate of hydrogen peroxide is (V1 / V0)×100%, where V1 is the volume of sodium thiosulfate standard solution consumed after low-temperature storage, and V0 is the volume consumed by the fresh sample. The higher this value, the better the stability of hydrogen peroxide under low-temperature conditions.

[0069] VII. Hair Tensile Strength Test

[0070] (I) Sample Preparation: Select coarse, undyed hair strands with a diameter within the range of 0.08mm ± 0.01mm. Divide the selected hair strands into two groups: one group is dyed according to the method described in the example, serving as the test group; the other group is not dyed, serving as the control group. Prepare 10 hair strands for each group, with each hair strand being 5cm in length. Fix both ends of the hair strands to a glass slide with glue, ensuring an effective test length of 3cm.

[0071] (II) Tensile test: The hair bundles were subjected to tensile test using a hair tensile testing machine (model: Instron5944). The tensile speed was set to 10 mm / min. During the tensile process, the maximum tensile force F when each hair bundle broke was carefully recorded.

[0072] (III) Calculation of retention rate: The formula for calculating the tensile strength retention rate is (average F value of test group / average F value of blank group) × 100%. The higher the value, the less damage to the hair after dyeing.

[0073] Example 1

[0074] Black version (basic formula, Agent A: Agent B = 1:1)

[0075] Agent A (100 parts by weight): 1.5 parts 2,4-diaminoethoxybenzene sulfate, 0.1 parts 4-aminom-cresol, 3.0 parts henna extract, 0.5 parts gallnut extract, 3.0 parts panthenol, 1.0 part ceramide, 2.0 parts centella asiatica extract, 5.0 parts monoethanolamine, 1.0 part thickener (hydroxyethyl cellulose), 2.0 parts hair oil (lanolin), 82.9 parts deionized water;

[0076] Agent B (100 parts by weight): 4.0 parts hydrogen peroxide, 0.3 parts phosphoric acid, 1.0 part emulsifier (Tween-80), 0.2 parts EDTA-2Na, 94.5 parts deionized water (pH=3.0).

[0077] Specific preparation method:

[0078] Preparation of Agent A: ① Heat 82.9 parts of deionized water to 45℃, add 5.0 parts of monoethanolamine and stir until completely dissolved; ② Add 1.0 part of hydroxyethyl cellulose and homogenize at 4000 r / min for 6 minutes to form a paste base; ③ Cool to 38℃, add 1.5 parts of 2,4-diaminoethoxybenzene sulfate and 0.1 parts of 4-aminom-cresol, and stir for 4 minutes; ④ Add 3.0 parts of henna extract, 0.5 parts of gallnut extract, 3.0 parts of panthenol, 1.0 part of ceramide, 2.0 parts of centella asiatica extract, and 2.0 parts of lanolin, and stir for 25 minutes; ⑤ Check pH = 9.0, and after passing the test, degas and fill.

[0079] Preparation of Agent B: ① Add 0.3 parts of phosphoric acid to 94.5 parts of deionized water and stir at room temperature until the pH stabilizes at 3.0; ② Add 4.0 parts of hydrogen peroxide dropwise at a rate of 1.5 mL / s while stirring at 1500 r / min; ③ Add 1.0 part of Tween-80 and 0.2 parts of EDTA-2Na and stir for 18 minutes; ④ Fill in the container away from light.

[0080] The test results for preparing the hair dye in this embodiment are as follows:

[0081] Scalp irritation rate: 0% (1 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; coloring time (25℃): 35 minutes; uniformity score: 80 points (ΔE = 0.8); 4-week fading rate: 17%; tensile strength retention rate: 85%; hairline staining rate: 25%.

[0082] Example 2

[0083] Black version (contains temperature-sensitive film-forming agent, A agent: B agent = 1:1)

[0084] Agent A (100 parts by weight): 1.5 parts 2,4-diaminoethoxybenzene sulfate, 0.1 parts 4-aminom-cresol, 3.0 parts henna extract, 0.5 parts gallnut extract, 3.0 parts panthenol, 1.0 part ceramide, 2.0 parts centella asiatica extract, 5.0 parts monoethanolamine, 1.0 part thickener (hydroxyethyl cellulose), 2.0 parts hair oil (lanolin), 1.2 parts thermosensitive film-forming agent (polyethylene glycol-60 hydrogenated castor oil: hydroxypropyl methylcellulose = 1:1.2), 81.7 parts deionized water;

[0085] Agent B (100 parts by weight): Same formulation as Agent B in Example 1.

[0086] Specific preparation method:

[0087] Preparation of Agent A: ① Heat 81.7 parts of deionized water to 45℃, add 5.0 parts of monoethanolamine and stir until completely dissolved; ② Add 1.0 part of hydroxyethyl cellulose and homogenize at 4000 r / min for 6 minutes to form a paste base; ③ Cool to 38℃, add 1.5 parts of 2,4-diaminoethoxybenzene sulfate and 0.1 parts of 4-aminom-cresol, and stir for 4 minutes; ④ Add 3.0 parts of henna extract, 0.5 parts of gallnut extract, 3.0 parts of panthenol, 1.0 part of ceramide, 2.0 parts of centella asiatica extract, and 2.0 parts of lanolin, and simultaneously add 1.2 parts of thermosensitive film-forming agent, and stir for 28 minutes; ⑤ Check pH = 9.1, and after passing the test, defoam and fill.

[0088] Preparation of Agent B: Same as the preparation method of Agent B in Example 1.

[0089] The test results for preparing the hair dye in this embodiment are as follows:

[0090] Scalp irritation rate: 0% (1 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; coloring time (25℃): 35 minutes; uniformity score: 80 points (ΔE = 0.8); 4-week fading rate: 16%; tensile strength retention rate: 86%; hairline staining rate: 5%.

[0091] Example 3

[0092] Black version (contains nisin, A agent: B agent = 1:1)

[0093] Agent A (100 parts by weight): 1.5 parts 2,4-diaminoethoxybenzene sulfate, 0.1 parts 4-aminom-cresol, 3.0 parts henna extract, 0.5 parts gallnut extract, 3.0 parts panthenol, 1.0 part ceramide, 2.0 parts centella asiatica extract, 5.0 parts monoethanolamine, 1.0 part thickener (hydroxyethyl cellulose), 2.0 parts hair oil (lanolin), 0.6 parts nisin, 82.3 parts deionized water;

[0094] Agent B (100 parts by weight): Same formulation as Agent B in Example 1.

[0095] Specific preparation method:

[0096] Preparation of Agent A: ① Heat 82.3 parts of deionized water to 45℃, add 5.0 parts of monoethanolamine and stir until completely dissolved; ② Add 1.0 part of hydroxyethyl cellulose and homogenize at 4000 r / min for 6 minutes to form a paste base; ③ Cool to 38℃, add 1.5 parts of 2,4-diaminoethoxybenzene sulfate and 0.1 parts of 4-aminom-cresol, and stir for 4 minutes; ④ Add 0.6 parts of nisin, and stir for 5 minutes; ⑤ Add 3.0 parts of henna extract, 0.5 parts of gallnut extract, 3.0 parts of panthenol, 1.0 part of ceramide, 2.0 parts of centella asiatica extract, and 2.0 parts of lanolin, and stir for 25 minutes; ⑥ Check pH = 9.0, and after passing the test, degas and fill.

[0097] Preparation of Agent B: Same as the preparation method of Agent B in Example 1.

[0098] The test results of the hair dye prepared in this embodiment are as follows (test for coarse and stiff hair):

[0099] Scalp irritation rate: 0% (1 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; Coloring time (25°C): 20 minutes (35 minutes in Example 1); Uniformity score: 85 points (ΔE = 0.6, 0.8 in Example 1); 4-week fading rate: 17%; Tensile strength retention rate: 84%.

[0100] Example 4

[0101] Black version (contains thermosensitive film-forming agent + nisin, A agent: B agent = 1:1)

[0102] Agent A (100 parts by weight): 1.5 parts 2,4-diaminoethoxybenzene sulfate, 0.1 parts 4-aminom-cresol, 3.0 parts henna extract, 0.5 parts gallnut extract, 3.0 parts panthenol, 1.0 part ceramide, 2.0 parts centella asiatica extract, 5.0 parts monoethanolamine, 1.0 part thickener (hydroxyethyl cellulose), 2.0 parts hair oil (lanolin), 1.2 parts thermosensitive film-forming agent (polyethylene glycol-60 hydrogenated castor oil: hydroxypropyl methylcellulose = 1:1.2), 0.6 parts nisin, 81.1 parts deionized water;

[0103] Agent B (100 parts by weight): Same formulation as Agent B in Example 1.

[0104] Specific preparation method:

[0105] Preparation of Agent A: ① Heat 81.1 parts of deionized water to 45℃, add 5.0 parts of monoethanolamine and stir until completely dissolved; ② Add 1.0 part of hydroxyethyl cellulose and homogenize at 4000 r / min for 6 minutes to form a paste base; ③ Cool to 38℃, add 1.5 parts of 2,4-diaminoethoxybenzene sulfate and 0.1 parts of 4-aminom-cresol, and stir for 4 minutes; ④ Add 0.6 parts of nisin, and stir for 5 minutes; ⑤ Add 3.0 parts of henna extract, 0.5 parts of gallnut extract, 3.0 parts of panthenol, 1.0 part of ceramide, 2.0 parts of centella asiatica extract, and 2.0 parts of lanolin, and simultaneously add 1.2 parts of thermosensitive film-forming agent, and stir for 28 minutes; ⑥ Check pH = 9.0, and after passing the test, defoam and fill.

[0106] Preparation of Agent B: Same as the preparation method of Agent B in Example 1.

[0107] The test results of the hair dye prepared in this embodiment are as follows (test for coarse and stiff hair):

[0108] Scalp irritation rate: 0% (1 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; coloring time (25℃): 20 minutes; uniformity score: 85 points (ΔE = 0.6); 4-week fading rate: 16%; tensile strength retention rate: 85%; hairline staining rate: 4%.

[0109] Example 5

[0110] Black version (contains thermosensitive film-forming agent + nisin + trehalose, A agent: B agent = 1:1)

[0111] Agent A (100 parts by weight): Same formulation as Agent A in Example 4;

[0112] Agent B (100 parts by weight): 4.0 parts hydrogen peroxide, 0.3 parts phosphoric acid, 1.0 part emulsifier (Tween-80), 0.2 parts EDTA-2Na, 0.2 parts trehalose, 94.3 parts deionized water (pH=3.0).

[0113] Specific preparation method:

[0114] Preparation of Agent A: Same as the preparation method of Agent A in Example 4;

[0115] Preparation of Agent B: ① Add 0.3 parts of phosphoric acid to 94.3 parts of deionized water and stir at room temperature until the pH stabilizes at 3.0; ② Add 4.0 parts of hydrogen peroxide dropwise at a rate of 1.5 mL / s while stirring at 1500 r / min; ③ Add 1.0 part of Tween-80, 0.2 parts of EDTA-2Na, and 0.2 parts of trehalose, and stir for 18 minutes; ④ Fill in the container away from light.

[0116] The test results for the hair dye prepared in this embodiment are as follows (coarse and stiff hair + 12℃ low temperature test):

[0117] Scalp irritation rate: 0% (2 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; Coloring time (12℃): 22 minutes (28 minutes in Example 4 at 12℃); Uniformity score: 85 points (ΔE = 0.7); 4-week fading rate: 16%; Tensile strength retention rate: 85%; Hairline staining rate: 4%; Hydrogen peroxide activity retention rate: 85% (the hair dye prepared in Example 4 had a hydrogen peroxide activity retention rate of 55% when tested at 12℃).

[0118] Example 6

[0119] Natural Brown Formula (Contains thermosensitive film-forming agent + nisin, Agent A: Agent B = 1:1)

[0120] Agent A (100 parts by weight): 1.0 part of 2,4-diaminoethoxybenzene sulfate, 0.8 parts of 4-aminom-cresol, 1.5 parts of walnut shell extract, 2.5 parts of panthenol, 2.0 parts of ceramide, 2.5 parts of centella asiatica extract, 4.0 parts of monoethanolamine, 0.8 parts of thickener (carbomer), 1.5 parts of hair oil (jojoba oil), 1.0 part of thermosensitive film-forming agent (polyethylene glycol-60 hydrogenated castor oil: hydroxypropyl methylcellulose = 1:1.5), 0.5 parts of nisin, 82.4 parts of deionized water;

[0121] Agent B (100 parts by weight): 6.0 parts hydrogen peroxide, 0.2 parts phosphoric acid, 0.8 parts emulsifier (Span-60), 0.2 parts EDTA-2Na, and 92.8 parts deionized water (pH=2.8).

[0122] Specific preparation method:

[0123] Preparation of Agent A: ① Heat 82.4 parts of deionized water to 42℃, add 4.0 parts of monoethanolamine and stir until completely dissolved; ② Add 0.8 parts of carbomer and homogenize at 3500 r / min for 7 minutes to form a paste base; ③ Cool to 36℃, add 1.0 part of 2,4-diaminoethoxybenzene sulfate and 0.8 parts of 4-aminom-cresol, and stir for 3 minutes; ④ Add 0.5 parts of nisin, and stir for 5 minutes; ⑤ Add 1.5 parts of walnut shell extract, 2.5 parts of panthenol, 2.0 parts of ceramide, 2.5 parts of centella asiatica extract, and 1.5 parts of jojoba oil, and simultaneously add 1.0 part of a thermosensitive film-forming agent, and stir for 25 minutes; ⑥ Check pH = 8.8, and after passing the test, degas and fill.

[0124] Preparation of Agent B: ① Add 0.2 parts of phosphoric acid to 92.8 parts of deionized water and stir at room temperature until the pH stabilizes at 2.8; ② Add 6.0 parts of hydrogen peroxide dropwise at a rate of 1.2 mL / s while stirring at 1200 r / min; ③ Add 0.8 parts of Span-60 and 0.2 parts of EDTA-2Na and stir for 16 minutes; ④ Fill in the container away from light.

[0125] The test results of the hair dye prepared in this embodiment are as follows (test for coarse and stiff hair):

[0126] Scalp irritation rate: 10% (1 out of 10 people scored 2 points, and 1 out of 10 people scored 1 point); 24-hour sensitization rate: 0%; coloring time (25℃): 23 minutes; uniformity score: 82 points (ΔE = 0.7); 4-week fading rate: 15%; tensile strength retention rate: 88%; hairline staining rate: 6%.

[0127] Example 7

[0128] Golden Brown Formula (Contains trehalose, A agent: B agent = 1:1.5)

[0129] Agent A (100 parts by weight): 0.6 parts 2,4-diaminoethoxybenzene sulfate, 0.3 parts 4-aminom-cresol, 0.2 parts curcumin, 4.0 parts panthenol, 1.5 parts ceramide, 2.0 parts Centella asiatica extract, 6.0 parts monoethanolamine, 1.2 parts thickener (xanthan gum), 2.5 parts hair oil (olive oil), 81.7 parts deionized water;

[0130] Agent B (100 parts by weight): 9.0 parts hydrogen peroxide, 0.4 parts phosphoric acid, 1.2 parts emulsifier (Tween-80), 0.25 parts EDTA-2Na, 0.25 parts trehalose, and 88.9 parts deionized water (pH=3.2).

[0131] Specific preparation method:

[0132] Preparation of Agent A: ① Heat 81.7 parts of deionized water to 48℃, add 6.0 parts of monoethanolamine and stir until completely dissolved; ② Add 1.2 parts of xanthan gum and homogenize at 5000 r / min for 5 minutes to form a paste base; ③ Cool to 39℃, add 0.6 parts of 2,4-diaminoethoxybenzene sulfate and 0.3 parts of 4-aminom-cresol, and stir for 5 minutes; ④ Add 0.2 parts of curcumin, 4.0 parts of panthenol, 1.5 parts of ceramide, 2.0 parts of Centella asiatica extract, and 2.5 parts of olive oil, and stir for 30 minutes; ⑤ Check pH = 9.5, and after passing the test, degas and fill.

[0133] Preparation of Agent B: ① Add 0.4 parts of phosphoric acid to 88.9 parts of deionized water and stir at room temperature until the pH stabilizes at 3.2; ② Add 9.0 parts of hydrogen peroxide dropwise at a rate of 2.0 mL / s while stirring at 2500 r / min; ③ Add 1.2 parts of Tween-80, 0.25 parts of EDTA-2Na, and 0.25 parts of trehalose, and stir for 20 minutes; ④ Fill in the container away from light.

[0134] The test results of the hair dye preparation in this embodiment are as follows (low temperature test at 12℃):

[0135] Scalp irritation rate: 30% (3 out of 10 participants scored 2 points, and 2 out of 10 participants scored 1 point); 24-hour sensitization rate: 0%; Coloring time (12℃): 35 minutes (50 minutes for the control group without trehalose); Uniformity score: 75 points (ΔE = 0.9); 4-week fading rate: 20%; Tensile strength retention rate: 80%; Hydrogen peroxide activity retention rate: 83%.

[0136] Comparative Example 1

[0137] Black version (contains PPD + no soothing agent, A agent: B agent = 1:1)

[0138] Agent A (100 parts by weight): p-phenylenediamine (PPD) 1.2 parts, resorcinol 0.8 parts, henna extract 3.0 parts, gallnut extract 0.5 parts, ethanolamine 5.0 parts, thickener (hydroxyethyl cellulose) 1.0 part, hair oil (mineral oil) 2.0 parts, deionized water 86.5 parts;

[0139] Agent B (100 parts by weight): Same formulation as Agent B in Example 1.

[0140] Specific preparation method:

[0141] Preparation of Agent A: ① Heat 86.5 parts of deionized water to 45℃, add 5.0 parts of ethanolamine and stir until completely dissolved; ② Add 1.0 part of hydroxyethyl cellulose and homogenize at 4000 r / min for 6 minutes to form a paste base; ③ Cool to 38℃, add 1.2 parts of PPD and 0.8 parts of resorcinol, and stir for 4 minutes; ④ Add 3.0 parts of henna extract, 0.5 parts of gallnut extract, and 2.0 parts of mineral oil, and stir for 25 minutes; ⑤ Check pH = 9.2, and after passing the test, degas and fill.

[0142] Preparation of Agent B: Same as the preparation method of Agent B in Example 1.

[0143] The test results of this comparative hair dye preparation are as follows:

[0144] Scalp irritation rate: 60% (4 out of 10 people scored 3 points, and 2 people scored 2 points); 24-hour sensitization rate: 30% (3 people scored 2 points); Coloring time (25℃): 20 minutes; Uniformity score: 75 points (ΔE = 1.2); 4-week fading rate: 25%; Tensile strength retention rate: 65%.

[0145] Comparative Example 2

[0146] Natural Brown Formula (No Lactococcal Peptide, A Agent: B Agent = 1:1)

[0147] Agent A (100 parts by weight): 1.0 part of 2,4-diaminoethoxybenzene sulfate, 0.8 part of 4-aminom-cresol, 1.5 part of walnut shell extract, 2.5 parts of panthenol, 2.0 part of ceramide, 2.5 parts of centella asiatica extract, 4.0 part of ethanolamine, 0.8 part of thickener (carbomer), 1.5 parts of hair oil (jojoba oil), 82.9 parts of deionized water;

[0148] Agent B (100 parts by weight): Same formulation as Agent B in Example 6.

[0149] Specific preparation method:

[0150] Preparation of Agent A: ① Heat 82.9 parts of deionized water to 42℃, add 4.0 parts of ethanolamine and stir until completely dissolved; ② Add 0.8 parts of carbomer and homogenize at 3500 r / min for 7 minutes to form a paste base; ③ Cool to 36℃, add 1.0 part of 2,4-diaminoethoxybenzene sulfate and 0.8 parts of 4-aminom-cresol, and stir for 3 minutes; ④ Add 1.5 parts of walnut shell extract, 2.5 parts of panthenol, 2.0 parts of ceramide, 2.5 parts of centella asiatica extract, and 1.5 parts of jojoba oil, and stir for 25 minutes; ⑤ Check pH = 8.8, and after passing the test, degas and fill.

[0151] Preparation of Agent B: Same as the preparation method of Agent B in Example 6.

[0152] The test results of the comparative hair dye preparation are as follows (for coarse and stiff hair):

[0153] Scalp irritation rate: 20% (2 out of 10 people scored 2 points); 24-hour sensitization rate: 0%; coloring time (25°C): 30 minutes (23 minutes in Example 6); uniformity score: 75 points (ΔE = 1.3, 0.7 in Example 6); 4-week fading rate: 16%; tensile strength retention rate: 87%.

[0154] Comparative Example 3

[0155] Golden Brown (Trehalose-free, A agent: B agent = 1:1.5)

[0156] Agent A (100 parts by weight): Same formulation as Agent A in Example 7;

[0157] Agent B (100 parts by weight): 9.0 parts hydrogen peroxide, 0.4 parts phosphoric acid, 1.2 parts emulsifier (Tween-80), 0.25 parts EDTA-2Na, and 89.15 parts deionized water (pH=3.2).

[0158] Specific preparation method:

[0159] Preparation of Agent A: Same as the preparation method of Agent A in Example 7;

[0160] Preparation of Agent B: ① Add 0.4 parts of phosphoric acid to 89.15 parts of deionized water and stir at room temperature until the pH stabilizes at 3.2; ② Add 9.0 parts of hydrogen peroxide dropwise at a rate of 2.0 mL / s while stirring at 2500 r / min; ③ Add 1.2 parts of Tween-80 and 0.25 parts of EDTA-2Na and stir for 20 minutes; ④ Fill in the container in the dark.

[0161] The test results of the comparative hair dye preparation are as follows (low temperature test at 12℃):

[0162] Scalp irritation rate: 30% (3 out of 10 people scored 2 points); 24-hour sensitization rate: 0%; coloring time (12℃): 50 minutes (35 minutes in Example 7); uniformity score: 65 points (ΔE = 2.1, 0.9 in Example 7); 4-week fading rate: 22%; tensile strength retention rate: 78%; hydrogen peroxide activity retention rate: 55% (83% in Example 7).

[0163] The foregoing description of specific exemplary embodiments of the invention is for illustrative and explanatory purposes. These descriptions are not intended to limit the invention to the precise forms disclosed, and it will be apparent that many changes and variations can be made in accordance with the foregoing teachings. The exemplary embodiments were chosen and described in order to explain the specific principles of the invention and its practical application, thereby enabling those skilled in the art to implement and utilize various different exemplary embodiments of the invention, as well as various different choices and variations. The scope of the invention is intended to be defined by the claims and their equivalents.

Claims

1. A safe multi-color hair dye for men, characterized in that, The men's multi-color safe hair dye consists of Agent A as the dye base and Agent B as the oxidizing agent, with a mass ratio of Agent A to Agent B of 1:(1-1.5). Each 100 parts by weight of Agent A includes the following components: 0.6-3.0 parts of dye precursor, 0.5-5.0 parts of natural pigment, 3.0-8.0 parts of soothing agent, 3.0-7.0 parts of alkalizing agent, 0.5-2.0 parts of thickener, 1.0-3.0 parts of hair oil, and the balance being deionized water; Each 100 parts by weight of Agent B comprises the following components: 3.0-10.0 parts hydrogen peroxide, 0.1-0.5 parts phosphoric acid, 0.5-1.5 parts emulsifier, 0.1-0.3 parts disodium ethylenediaminetetraacetate, with the balance being deionized water. The pH value of Agent B is 2.5-3.

5.

2. The men's multi-color safe hair dye as described in claim 1, characterized in that, In Agent A, the dye precursor is composed of 2,4-diaminoethoxyphenyl sulfate and 4-aminom-cresol in a mass ratio of 1:(0.02-1.25).

3. The men's multi-color safe hair dye as described in claim 1, characterized in that, In Agent A, the alkalizing agent is at least one of monoethanolamine, diethanolamine, and triethanolamine.

4. The men's multi-color safe hair dye as described in claim 1, characterized in that, In Agent A, the natural pigment is selected from at least one of henna extract, gallnut extract, walnut shell extract, and curcumin.

5. The men's multi-color safe hair dye as described in claim 1, characterized in that, In Agent A, the soothing agent is composed of panthenol, ceramide, and centella asiatica extract in a mass ratio of 1:(0.1-3):(0.2-4).

6. The men's multi-color safe hair dye as described in claim 1, characterized in that, For coarse and stiff hair, Agent A also includes 0.3-0.8 parts of nisin.

7. The men's multi-color safe hair dye as described in claim 1, characterized in that, Agent A also includes 0.5-2.0 parts of a thermosensitive film-forming agent; the thermosensitive film-forming agent is a compound of polyethylene glycol-60 hydrogenated castor oil and hydroxypropyl methylcellulose in a mass ratio of 1:(1-1.5).

8. The men's multi-color safe hair dye as described in claim 1, characterized in that, Agent B also includes 0.1-0.3 parts of trehalose; the mass ratio of trehalose to disodium EDTA is 1:(0.5-1).

9. The men's multi-color safe hair dye as described in claim 1, characterized in that, For men's preferred color schemes, the specific formulations of Agent A and Agent B in different color schemes include: Black version: Each 100 parts by weight of Agent A includes 1.3-1.7 parts of 2,4-diaminoethoxybenzene sulfate, 0.05-0.15 parts of 4-aminom-cresol, 2.5-4.0 parts of henna extract, and 0.3-0.7 parts of gallnut extract; each 100 parts by weight of Agent B includes 3.0-5.0 parts of hydrogen peroxide. Natural Brown: Every 100 parts by weight of Agent A includes 0.8-1.2 parts of 2,4-diaminoethoxybenzene sulfate, 0.7-0.9 parts of 4-aminom-cresol, and 1.0-2.0 parts of walnut shell extract; every 100 parts by weight of Agent B includes 5.0-7.0 parts of hydrogen peroxide. Golden Brown Formula: Every 100 parts by weight of Agent A includes 0.5-0.7 parts of 2,4-diaminoethoxybenzene sulfate, 0.2-0.4 parts of 4-aminom-cresol, and 0.1-0.3 parts of curcumin; every 100 parts by weight of Agent B includes 8.0-10.0 parts of hydrogen peroxide.

10. The method for preparing the multi-color safe hair dye for men as described in any one of claims 1-9, characterized in that, Includes the following steps: Preparation of Agent A: ① Heat deionized water to 40-50℃, add alkalizing agent and stir until completely dissolved; ② Add thickener and homogenize at 3000-5000r / min for 5-8 minutes to form a paste base; ③ Cool to 35-40℃, add dye precursor and stir for 3-5 minutes; ④ If it is a formula for coarse and hard hair, add nisin and stir for 5 minutes; ⑤ Add natural pigment, soothing agent and hair oil; if it contains temperature-sensitive film-forming agent, add it in this step and stir for 20-30 minutes; ⑥ Test the pH value to 8.5-9.5, and after passing the test, defoam and fill the package; Preparation of Agent B: ① Add phosphoric acid to deionized water and stir at room temperature until the pH value stabilizes at 2.5-3.5; ② Slowly add hydrogen peroxide dropwise at a rate of 1-2 mL / s while stirring at 1000-2500 r / min; ③ Add emulsifier and EDTA-2Na; If it contains trehalose, add it in this step and stir for 15-20 minutes; ④ Fill in the dark.