Preparation method and application of astaxanthin microcapsule powder

By employing a two-stage supercritical extraction and spray drying technology, astaxanthin microcapsule powder with high encapsulation rate and no fishy smell was prepared, solving the problems of low encapsulation rate and inability to mask fishy smell in existing technologies. This enabled the preparation of high-content astaxanthin microcapsule powder and improved bioavailability.

CN120898972APending Publication Date: 2025-11-07CHENGUANG BIOTECH GRP CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202511118698.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-11
Publication Date
2025-11-07

AI Technical Summary

Technical Problem

Existing astaxanthin microcapsule powder products have low encapsulation rates, cannot completely mask the fishy smell, cannot meet the requirements for high content, and have poor bioavailability.

Method used

A two-stage supercritical extraction technique was used, combined with modified starch and an entrainer, to prepare a fluid with high astaxanthin content. The fluid was then spray-dried to form microcapsule powder with a particle size of 100-150 nm, which improved the encapsulation rate and removed the fishy smell.

Benefits of technology

It improved the encapsulation rate and bioavailability of astaxanthin microcapsule powder, reduced the fishy smell, and enhanced the taste and efficacy of the final product.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN120898972A_ABST
    Figure CN120898972A_ABST
Patent Text Reader

Abstract

The invention discloses a preparation method and application of astaxanthin microcapsule powder, and belongs to the technical field of foods.The preparation method comprises the following steps that S1, a wall material solution is prepared, specifically, modified starch and maltodextrin are added into water, heated and stirred till complete dissolution is achieved, and the wall material solution is prepared; s2, astaxanthin fluid preparation: astaxanthin oil is subjected to two-stage supercritical extraction, grease is obtained through first-stage supercritical extraction, and high-content astaxanthin carbon dioxide fluid is obtained through second-stage supercritical extraction; s3, the wall material solution obtained in the step S1 is added into a separation kettle II, the astaxanthin carbon dioxide fluid obtained through second-stage supercritical extraction in the step S2 is released and mixed with the wall material solution in the separation kettle II, and astaxanthin emulsion is obtained; and S4, performing spray drying to obtain the astaxanthin microcapsule powder. The supercritical astaxanthin fluid can be prepared through the method, the particle size of astaxanthin is reduced, the product embedding rate is increased, and the fishy smell of astaxanthin is reduced.
Need to check novelty before this filing date? Find Prior Art

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of food, and particularly relates to a preparation method of astaxanthin microcapsule powder with high embedding rate and no fishy smell and application thereof. BACKGROUND

[0002] Astaxanthin is a terpene carotenoid with good coloring function and strong biological activity. Astaxanthin from Haematococcus pluvialis is the strongest natural antioxidant known at present, and has been applied in food and beverage, cosmetics and medicine as a new active factor, and has great market potential. Astaxanthin belongs to a non-polar substance, and is insoluble in water and slightly soluble in oil, which results in poor water solubility of astaxanthin, limited oral bioavailability, poor bioavailability, and great limitation of the application of astaxanthin.

[0003] Microcapsule technology is a technology of embedding solid, liquid and gas substances in a capsule material to form a small closed system. This method can not only isolate and protect the embedded substances from light and oxygen, slow down the oxidation and improve the stability, but also effectively mask the special smell of the core material, and control the release rate of the drug. Therefore, astaxanthin can be embedded by microcapsule technology to improve the storage stability.

[0004] The astaxanthin microcapsule powder product on the market mainly has a specification of 2% or 3%, and the preparation process uses 10% astaxanthin oil, emulsifier and antioxidant as an oil phase, and uses modified starch and other wall materials as a water phase to perform homogenization and spray. Due to the low content (10%) of astaxanthin raw material, the amount of wall material added is small, which results in low embedding rate of the product and the inability to completely wrap the fishy smell of astaxanthin. In addition, the demand for high-content astaxanthin microcapsule powder in the market is increasing, but high-content astaxanthin microcapsule powder cannot be prepared due to the low content of astaxanthin oil.

[0005] In view of the above problems, it is urgent to develop a process for preparing astaxanthin microcapsule powder with high embedding rate and no fishy smell. SUMMARY

[0006] To solve the above problems, the application provides a preparation method and application of astaxanthin microcapsule powder. The astaxanthin microcapsule powder prepared by the method has high embedding rate and no fishy smell.

[0007] To achieve the above purpose, the technical scheme adopted by the application is as follows:

[0008] A preparation method of astaxanthin microcapsule powder, comprising the following steps:

[0009] S1: wall material solution preparation: adding modified starch and malt dextrin into water, heating and stirring until completely dissolved to prepare a wall material solution;

[0010] S2: astaxanthin fluid preparation: astaxanthin oil is subjected to two-stage supercritical extraction, the first stage supercritical extraction obtains oil, and the second stage supercritical extraction obtains astaxanthin carbon dioxide fluid with high content;

[0011] S3: the wall material solution obtained in step S1 is added into a separation kettle II, and the astaxanthin carbon dioxide fluid obtained in the second stage supercritical extraction in S2 is released in the separation kettle II and mixed with the wall material solution to obtain an astaxanthin emulsion;

[0012] S4: spray drying to obtain astaxanthin microcapsule powder.

[0013] Further improvement of the technical scheme of the present application is that the denatured starch in step S1 is one or more of sodium octenyl succinate starch, potato porous starch and cassava porous starch, the mass ratio of the denatured starch and malt dextrin is 3:1, the amount of water is 1-1.5 times that of the denatured starch and malt dextrin, and the heating temperature is 40-60 DEG C.

[0014] Further improvement of the technical scheme of the present application is that in step S2, the extraction kettle temperature of the first stage supercritical extraction is 40-60 DEG C, the extraction pressure is 20-40 MPa, the separation kettle I temperature is 30-40 DEG C, the pressure is 4-6 MPa, the extraction time is 2-4 h, and the carbon dioxide flow is 200-400 L / h.

[0015] Further improvement of the technical scheme of the present application is that in step S2, the extraction kettle temperature of the second stage supercritical extraction is 40-60 DEG C, the extraction pressure is 60-80 MPa, the separation kettle II temperature is 35-50 DEG C, the pressure is 4-6 MPa, the extraction time is 1-3 h, and the carbon dioxide flow is 200-400 L / h.

[0016] Further improvement of the technical scheme of the present application is that the entrainer used in the second stage supercritical extraction in step S2 is phospholipid and VE, and the phospholipid is one or more of soybean phospholipid, lecithin and sunflower phospholipid.

[0017] Further improvement of the technical scheme of the present application is that in step S3, the astaxanthin carbon dioxide fluid is released in the separation kettle II and dissolved in the wall material solution, and the dissolution process is assisted by ultrasonic, wherein the proportion of denatured starch is 30-60%, the proportion of malt dextrin is 10-20%, the proportion of 10% astaxanthin oil is 17-60%, the proportion of phospholipid is 0.5-2%, and the proportion of VE is 0.5-1%.

[0018] Further improvement of the technical scheme of the present application is that the particle size of the astaxanthin emulsion obtained in step S3 is 100-150 nm.

[0019] Further improvement of the technical scheme of the present application is that the spray drying conditions in step S4 are as follows: material feeding flow rate is 25-35 mL / min, air inlet temperature is 175-190 DEG C, and air outlet temperature is 80-95 DEG C.

[0020] The astaxanthin microcapsule powder can be used for preparing a drink or a chewable tablet.

[0021] The numerical range of the present application includes not only the point values listed above, but also any point values between the above numerical ranges that are not listed, and the present application does not exhaustively list the specific point values included in the range for the sake of brevity and simplicity.

[0022] Thanks to the above technical scheme, the present application has the following technical progress:

[0023] The present application improves the astaxanthin content and removes the fishy smell by using the two-stage supercritical extraction, the first-stage supercritical extraction mainly extracts the oil in the astaxanthin oil, and the second-stage supercritical extraction mainly prepares high-content astaxanthin oil, the content of which reaches 20%-40%, the use amount of the wall material is increased, and the astaxanthin is better wrapped; secondly, the present application can prepare supercritical astaxanthin fluid, reduce the astaxanthin particle size (100-150 nm), improve the product embedding rate, and reduce the fishy smell of the astaxanthin, and improve the taste of the end product prepared by using the astaxanthin microcapsule powder as a raw material. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 The flow chart of the astaxanthin microcapsule powder preparation method of the present application. DETAILED DESCRIPTION

[0025] The technical scheme of the present application will be further described in detail below in combination with examples:

[0026] Example 1 (2% astaxanthin microcapsule powder)

[0027] A preparation method of high-embedding-rate and fishy-smell-free astaxanthin microcapsule powder, comprising the following steps:

[0028] (1) Wall material solution preparation: 300 g of octenyl succinic anhydride sodium starch and 100 g of maltodextrin are added to 400 g of distilled water, and stirred at 50 DEG C until completely dissolved to prepare a wall material solution;

[0029] (2) astaxanthin fluid preparation: 100 g astaxanthin oil (10% content) is added to a supercritical extraction kettle for supercritical extraction; first stage: extraction kettle temperature 45°C, pressure 20 MPa, separation kettle I temperature 35°C, pressure 5 MPa, extraction 2 h, carbon dioxide flow rate 200 L / h; second stage: extraction kettle temperature 50°C, pressure 65 MPa, separation kettle II temperature 45°C, pressure 5 MPa, extraction 3 h, carbon dioxide flow rate 300 L / h, and 7.5 g soybean phospholipid and 5 g VE are used as the entraining agent in the second stage.

[0030] (3) astaxanthin emulsion preparation: the wall material solution is added to separation kettle II before supercritical extraction, and the high-content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction is released and mixed in separation kettle II, and the mixing process is assisted by ultrasonic, to obtain an astaxanthin emulsion, and the emulsion particle size reaches 120 nm.

[0031] (4) Then spray drying is performed, the inlet air temperature is controlled to be 180°C, the outlet air temperature is controlled to be 85-90°C, and the feeding flow rate is controlled to be 30 ml / min, to obtain the astaxanthin microcapsule powder.

[0032] Example 2 (3% astaxanthin microcapsule powder)

[0033] A method for preparing astaxanthin microcapsule powder with high embedding rate and no fishy smell, comprising the following steps:

[0034] (1) Wall material solution preparation: 300 g of octenyl succinic anhydride sodium starch and 100 g of malt dextrin are added to 450 g of distilled water, and stirred at 50°C until completely dissolved, to obtain a wall material solution.

[0035] (2) astaxanthin fluid preparation: 156 g astaxanthin oil (10% content) is added to a supercritical extraction kettle for supercritical extraction; first stage: extraction kettle temperature 50°C, pressure 25 MPa, separation kettle I temperature 40°C, pressure 6 MPa, extraction 2.5 h, carbon dioxide flow rate 250 L / h; second stage: extraction kettle temperature 55°C, pressure 70 MPa, separation kettle II temperature 40°C, pressure 5 MPa, extraction 3 h, carbon dioxide flow rate 300 L / h, and 7.5 g lecithin and 5 g VE are used as the entraining agent.

[0036] (3) astaxanthin emulsion preparation: the wall material solution is added to separation kettle II before supercritical extraction, and the high-content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction is released and mixed in separation kettle II, and the mixing process is assisted by ultrasonic, to obtain an astaxanthin emulsion, and the emulsion particle size reaches 130 nm.

[0037] (4) Then spray drying, control the inlet air temperature is 180℃, the outlet air temperature is 85-90℃, the feed flow rate is 30ml / min, to obtain the astaxanthin microcapsule powder.

[0038] Example 3 (5% astaxanthin microcapsule powder)

[0039] A high-embedding-rate, non-fishy-smelling astaxanthin microcapsule powder and a preparation method thereof, comprising the following steps:

[0040] (1) Wall material solution preparation: 300g of sodium octenyl succinate starch and 100g of malt dextrin are added to 500g of distilled water, and stirred at 50℃ until completely dissolved to prepare a wall material solution;

[0041] (2) Astaxanthin fluid preparation: 264g of astaxanthin oil (content 10%) is added to a supercritical extraction kettle for supercritical extraction; first stage: extraction kettle temperature 55℃, pressure 30MPa, separation kettle I temperature 35℃, pressure 4MPa, extraction 3h, carbon dioxide flow 350L / h; second stage: extraction kettle temperature 55℃, pressure 75MPa, separation kettle II temperature 45℃, pressure 4MPa, extraction 2h, carbon dioxide flow 350L / h, entraining agent is 7.5g of lecithin and 5g of VE.

[0042] (3) Astaxanthin emulsion preparation: before supercritical extraction, the wall material solution is added to separation kettle II, and the high-content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction is released and mixed in separation kettle II, and the mixing process is assisted by ultrasonic, to obtain an astaxanthin emulsion with a particle size of 145nm.

[0043] (4) Then spray drying, control the inlet air temperature is 180℃, the outlet air temperature is 85-90℃, the feed flow rate is 30ml / min, to obtain the astaxanthin microcapsule powder.

[0044] Example 4 (8% astaxanthin microcapsule powder)

[0045] A high-embedding-rate, non-fishy-smelling astaxanthin microcapsule powder and a preparation method thereof, comprising the following steps:

[0046] (1) Wall material solution preparation: 300g of sodium octenyl succinate starch and 100g of malt dextrin are added to 500g of distilled water, and stirred at 50℃ until completely dissolved to prepare a wall material solution;

[0047] (2) Preparation of astaxanthin fluid: 580 g of astaxanthin oil (content 10%) was added to the supercritical extraction kettle, and supercritical extraction was carried out; the first stage: the temperature of the extraction kettle was 60°C, the pressure was 40 MPa, the temperature of the separation kettle I was 40°C, the pressure was 6 MPa, the extraction was carried out for 4 h, and the carbon dioxide flow rate was 400 L / h; the second stage: the temperature of the extraction kettle was 60°C, the pressure was 80 MPa, the temperature of the separation kettle II was 50°C, the pressure was 5 MPa, the extraction was carried out for 2 h, the carbon dioxide flow rate was 300 L / h, and the entraining agent was 7.5 g of lecithin and 5 g of VE.

[0048] (3) Preparation of astaxanthin emulsion: before supercritical extraction, the wall material solution was added to the separation kettle II, and the high-content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction was released and mixed in the separation kettle II, and the mixing process was assisted by ultrasonic, to obtain astaxanthin emulsion, and the particle size of the emulsion reached 105 nm.

[0049] (4) Then spray drying was carried out, the inlet air temperature was controlled to be 180°C, the outlet air temperature was controlled to be 85-90°C, the feeding flow rate was 30 ml / min, and astaxanthin microcapsule powder was obtained.

[0050] Comparative Example 1

[0051] (1) Preparation of wall material solution: 300 g of octenyl succinate sodium starch and 100 g of malt dextrin were added to 400 g of distilled water, and stirring was carried out at 50°C until complete dissolution, to obtain a wall material solution;

[0052] (2) Preparation of astaxanthin fluid: 100 g of astaxanthin oil (content 10%) was added to the supercritical extraction kettle, and supercritical extraction was carried out; without oil removal treatment, direct extraction was carried out, the temperature of the extraction kettle was 50°C, the pressure was 65 MPa, the temperature of the separation kettle II was 45°C, the pressure was 5 MPa, the extraction was carried out for 3 h, the carbon dioxide flow rate was 300 L / h, and the entraining agent was 7.5 g of soybean lecithin and 5 g of VE.

[0053] (3) Preparation of astaxanthin emulsion: before supercritical extraction, the wall material solution was added to the separation kettle II, and the astaxanthin fluid was released and mixed in the separation kettle II, and the mixing process was assisted by ultrasonic, to obtain astaxanthin emulsion, and the particle size of the emulsion reached 200 nm.

[0054] (4) Then spray drying was carried out, the inlet air temperature was controlled to be 180°C, the outlet air temperature was controlled to be 85-90°C, the feeding flow rate was 30 ml / min, and astaxanthin microcapsule powder was obtained.

[0055] Comparative Example 2

[0056] A high-embedding-rate, non-fishy-smell astaxanthin microcapsule powder and a preparation method thereof, comprising the following steps:

[0057] (1) Preparation of wall material solution: 300 g of sodium octenyl succinate starch and 100 g of maltodextrin were added to 400 g of distilled water, and stirred at 50°C until completely dissolved to prepare a wall material solution;

[0058] (2) Preparation of astaxanthin fluid: 100 g of astaxanthin oil (10% content) was added to a supercritical extraction kettle for supercritical extraction; first stage: extraction kettle temperature 65°C, pressure 50 MPa, separation kettle I temperature 45°C, pressure 5 MPa, extraction 2 h, carbon dioxide flow rate 200 L / h; second stage: extraction kettle temperature 50°C, pressure 65 MPa, separation kettle II temperature 45°C, pressure 5 MPa, extraction 3 h, carbon dioxide flow rate 300 L / h, and the entraining agent was 7.5 g of soybean phospholipid and 5 g of VE.

[0059] (3) Preparation of astaxanthin emulsion: before supercritical extraction, the wall material solution was added to separation kettle II, and the high content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction was released and mixed in separation kettle II, and the mixing process was assisted by ultrasonic, to obtain an astaxanthin emulsion, and the emulsion particle size reached 125 nm.

[0060] (4) Then spray drying, control the inlet air temperature to be 180°C, the outlet air temperature to be 85-90°C, and the feeding flow rate to be 30 ml / min, to obtain astaxanthin microcapsule powder.

[0061] Comparative Example 3

[0062] (1) Preparation of wall material solution: 300 g of sodium octenyl succinate starch and 100 g of maltodextrin were added to 400 g of distilled water, and stirred at 50°C until completely dissolved to prepare a wall material solution;

[0063] (2) Preparation of astaxanthin fluid: 100 g of astaxanthin oil (10% content) was added to a supercritical extraction kettle for supercritical extraction; first stage: extraction kettle temperature 35°C, pressure 15 MPa, separation kettle I temperature 45°C, pressure 5 MPa, extraction 1 h, carbon dioxide flow rate 150 L / h; second stage: extraction kettle temperature 50°C, pressure 65 MPa, separation kettle II temperature 45°C, pressure 5 MPa, extraction 3 h, carbon dioxide flow rate 300 L / h, and the entraining agent was 7.5 g of soybean phospholipid and 5 g of VE.

[0064] (3) Preparation of astaxanthin emulsion: before supercritical extraction, the wall material solution was added to separation kettle II, and the high content astaxanthin carbon dioxide fluid obtained in the second stage of supercritical extraction was released and mixed in separation kettle II, and the mixing process was assisted by ultrasonic, to obtain an astaxanthin emulsion, and the emulsion particle size reached 198 nm.

[0065] (4) Then spray drying, control the inlet air temperature is 180℃, the outlet air temperature is 85-90℃, the feed flow rate is 30ml / min, to obtain astaxanthin microcapsule powder.

[0066] Comparative Example 4 (conventional process)

[0067] (1) Wall material solution preparation: take 317g of octenyl succinate sodium starch, 130g of malt dextrin into 670g of distilled water, stir at 50℃ until completely dissolved, to prepare the wall material solution;

[0068] (2) Core material preparation: take 100g of astaxanthin oil (content 10%) as the core material, add 7g of soybean phospholipid and 5g of VE to the core material, and stir at 45℃ until completely dissolved.

[0069] (3) Add the astaxanthin and emulsifier-containing core material obtained in step (2) to the wall material solution obtained in step (1), and shear at a speed of 9000r / min for 12 minutes to obtain astaxanthin pre-emulsion;

[0070] (4) Emulsify the astaxanthin pre-emulsion of step (3) by high-pressure homogenizer, and then homogenize at a pressure of 55MPa for 2 times;

[0071] (5) Then spray drying, control the inlet air temperature is 180℃, the outlet air temperature is 85-90℃, the feed flow rate is 30ml / min, to obtain astaxanthin microcapsule powder.

[0072] Sample evaluation

[0073] 1. Absorption rate

[0074] The in vitro astaxanthin microcapsule powder digestion absorption rate test is carried out by constructing a simulated in vitro digestion model, weighing the sample at 1.5g (calculated by astaxanthin content), reacting in artificial gastric juice for 2h, and then transferring to artificial intestinal juice for 2h. By collecting the samples digested in gastric juice for 2h, intestinal juice for 1h, and intestinal juice for 2h, for subsequent detection of astaxanthin content and free astaxanthin content, and calculating the astaxanthin release rate according to the following formula:

[0075] Astaxanthin absorption rate = (free astaxanthin content before digestion - free astaxanthin content after digestion) / astaxanthin content before digestion x 100%

[0076] 2. Embedding rate

[0077] Astaxanthin microcapsule powder embedding rate determination:

[0078] Astaxanthin embedding rate = (1 - astaxanthin content on the surface of astaxanthin microcapsule powder / total astaxanthin content in astaxanthin microcapsule powder) x 100%.

[0079] Total astaxanthin content in astaxanthin microcapsule powder: 0.1 g of astaxanthin microcapsule powder was accurately weighed in a 100 ml volumetric flask, 5 ml of water was added and ultrasonic extraction was performed for 5 min, and then acetone was added to constant volume, and then liquid phase determination was performed.

[0080] Surface astaxanthin content in astaxanthin microcapsule powder: 0.1 g of astaxanthin microcapsule powder was accurately weighed in a 50 ml centrifuge tube, 10 ml of acetone was added, and then the mixture was gently shaken for 1 min, and then centrifuged at 6000 r / min for 10 min, and then the supernatant was taken into a 100 ml volumetric flask; the above steps were repeated 3 times, and then the combined supernatant was collected in a 100 ml volumetric flask, and then acetone was added to constant volume, and then liquid phase determination was performed.

[0081] 3. Retention rate

[0082] Astaxanthin microcapsule powder retention rate determination: The storage stability of astaxanthin microcapsule powder was investigated by accelerated test, and the storage conditions were 37°C, 75% RH (relative humidity), and the total astaxanthin content was determined after 3 months of storage.

[0083] Astaxanthin retention rate = (total astaxanthin content after 3 months of storage / original total astaxanthin content of astaxanthin microcapsule powder) x 100%.

[0084] 4. Evaluation of product fishiness degree and odor preference

[0085] The fishiness (odor) degree and odor preference of the above samples were evaluated by conducting internal sensory tests. 100 panelists participated in the sensory test, and the scores ranged from 1 to 5. In the fishiness degree dimension, 1 represents no obvious perception, 2 represents slight, 3 represents moderate, 4 represents obvious, and 5 represents very obvious; in the preference dimension, 1 represents very dislike, 2 represents a little dislike, 3 represents neither like nor dislike, 4 represents a little like, and 5 represents very like.

[0086] Table 1 Product performance evaluation

[0087]

[0088] From the above table data, it can be seen that the preparation method of astaxanthin microcapsule powder of the present application can prepare high content astaxanthin microcapsule powder with high embedding rate, and the astaxanthin microcapsule powder obtained by using conventional process without two-stage supercritical extraction is poor in product yield, fishiness degree, and absorption rate and retention rate, and if the supercritical extraction conditions of the present application are not used, the embedding rate or absorption rate will be greatly affected.

[0089] The high-content astaxanthin microcapsule powder prepared in the application can be used to prepare capsule preparations, or be compressed into tablets, or be made into powder tonics, and is widely used in dietary supplements and health products or functional foods and beverages. Since the astaxanthin microcapsule powder has lower fishy smell, the end product has better taste, and the eating experience of consumers is better.

Claims

1. A method for preparing astaxanthin microcapsule powder, characterized by: It comprises the following steps: S1: wall material solution preparation: denatured starch, malt dextrin is added to water, heated and stirred until completely dissolved to prepare a wall material solution; S2: astaxanthin fluid preparation: astaxanthin oil is subjected to two-stage supercritical extraction, the first stage supercritical extraction obtains oil, and the second stage supercritical extraction obtains astaxanthin carbon dioxide fluid with high content; S3: the wall material solution obtained in step S1 is added to a separation kettle II, and the astaxanthin carbon dioxide fluid obtained by the second stage supercritical extraction in S2 is released in the separation kettle II and mixed with the wall material solution to obtain an astaxanthin emulsion; S4: spray drying to obtain astaxanthin microcapsule powder.

2. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: The denatured starch in step S1 is one or more of sodium octenyl succinate starch, potato porous starch, and cassava porous starch, the mass ratio of denatured starch to malt dextrin is 3:1, the amount of water is 1-1.5 times that of denatured starch and malt dextrin, and the heating temperature is 40-60℃.

3. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: In step S2, the extraction kettle temperature for the first stage supercritical extraction is 40-60℃, the extraction pressure is 20-40MPa, the separation kettle I temperature is 30-40℃, the pressure is 4-6MPa, the extraction time is 2-4h, and the carbon dioxide flow is 200L-400L / h.

4. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: In step S2, the extraction kettle temperature for the second stage supercritical extraction is 40-60℃, the extraction pressure is 60-80MPa, the separation kettle II temperature is 35-50℃, the pressure is 4-6MPa, the extraction time is 1-3h, and the carbon dioxide flow is 200L-400L / h.

5. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: The entrainer used in the second stage supercritical extraction in step S2 is phospholipid and VE, and the phospholipid is one or more of soybean phospholipid, lecithin, and sunflower phospholipid.

6. The method for preparing astaxanthin microcapsule powder according to claim 5, characterized in that: In step S3, the astaxanthin carbon dioxide fluid is released in the separation kettle II and dissolved in the wall material solution, and the dissolution process is assisted by ultrasonic, and the mass ratio of each component in the astaxanthin microcapsule powder is: denatured starch 30-60%, malt dextrin 10-20%, 10% astaxanthin oil 17-60%, phospholipid 0.5-2%, and VE 0.5-1%.

7. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: The particle size of the astaxanthin emulsion obtained in step S3 is 100-150nm.

8. The method for preparing astaxanthin microcapsule powder according to claim 1, characterized in that: In step S4, the spray drying conditions are as follows: the material feeding flow rate is 25-35mL / min, the inlet air temperature is 175-190℃, and the outlet air temperature is 80-95℃.

9. Use of astaxanthin microcapsule powder, characterized in that: The astaxanthin microcapsule powder of any one of claims 1-8 is used for preparing a capsule preparation, a drink, or a chewable tablet.