A tumor sample collection device

Abstract

The application relates to the technical field of sample collection, and discloses a tumor sample collection device which comprises a sampling tube, a sliding sleeve sleeved outside the sampling tube, a sleeve connected to the top end of the sliding sleeve, an inner cylinder arranged in the sleeve, the sampling tube extending into the inner cylinder, two groups of storage tubes symmetrically arranged in the inner cylinder, and the storage tubes being in communication with the sampling tube; a sampling port is arranged at the bottom end of the sampling tube, a floater is arranged below the horizontal position of the sampling port in the sampling tube, and the floater is slidably connected to the sampling tube through a tension spring. The floater is elastically connected to the sampling tube through the tension spring, when the sampling tube completes sampling, a bidirectional pump is started to suck the sample, the floater can also be adsorbed, the floater is stretched after being adsorbed by the adsorption force, moves to the sampling port, and blocks the sampling port, so that sample leakage is effectively avoided, the integrity of the sampling tissue is ensured, and the accuracy of detection is ensured.

Description

Technical Field

[0001] This invention relates to the field of sample collection technology, specifically to a tumor sample collection device. Background Technology

[0002] A tumor is a mass-like disease that grows in various parts of the body. Tumors are divided into benign tumors and malignant tumors. Benign tumors are characterized by slow growth, clear boundaries, a complete capsule, and a relatively homogeneous texture. Malignant tumors are characterized by rapid growth, unclear boundaries, lack of a complete capsule, abundant blood flow signals within the tumor, and a firm texture. In the diagnostic process, it is usually necessary to extract a sample from the tumor for biopsy to determine whether the tumor is benign or malignant, so as to arrange different treatment methods according to different characteristics.

[0003] A tumor sampling needle and device, disclosed in publication number "CN115137409A", belongs to the field of medical device technology. The tumor sampling needle and device include an outer cylinder, an inner cylinder, a sampling needle, a collection cylinder, and an anti-slip sleeve. The sampling needle includes a needle body with a spiral blade and a tip at its end. The combination of these two elements allows for rapid puncture of the tumor, and rotating the tip can break through a small area of ​​the protective membrane on the tumor surface, solving the problem of excessively large wounds when using a scalpel to puncture a tumor. A V-shaped spatula is located at the top of the needle body. When the tumor is too small to be extracted using a suction method, the V-shaped spatula can be inserted into the tumor. When the V-shaped spatula is withdrawn, it carries a small amount of tumor sample for collection and testing by the doctor. Because the first magnet and the second magnet on the protective layer have the same magnetic poles and repel each other, the sampling needle will not puncture tissue when searching for tumors in the human body.

[0004] However, the existing technology and the above-mentioned technology still have the following drawbacks: 1. After sampling, the sampling port lacks a corresponding sealing device, making the sample prone to falling and being damaged, which may have a significant impact on the accuracy of subsequent testing. 2. After use, the sampling structure may leave sample residue on the sampling needle / tube wall, which may also cause sample loss and affect the test results. In addition, the residue on the sampling needle / tube wall that is not cleaned in time is not easy to remove. Summary of the Invention

[0005] This invention provides a tumor sample collection device that solves the problems mentioned in the background art, such as the lack of a corresponding sealing device at the collection port after sampling, which makes the sample easy to fall and be lost, potentially having a significant impact on the accuracy of subsequent detection; and the problem that after use, the sampling structure may leave sample residue on the sampling needle / tube wall, which can also cause sample loss and affect the detection results. In addition, the residue on the sampling needle / tube wall that is not cleaned in time is difficult to remove.

[0006] The present invention provides the following technical solution: a tumor sample collection device, including a sampling tube and a sliding sleeve sleeved outside the sampling tube. A sleeve is connected to the top of the sliding sleeve, and an inner cylinder is provided inside the sleeve. The sampling tube extends into the inner cylinder, and two sets of storage tubes are symmetrically arranged inside the inner cylinder. The storage tubes and the sampling tube are connected in communication. A sampling port is opened at the bottom of the sampling tube, and a floater is provided inside the sampling tube below the horizontal position of the sampling port. The floater is slidably connected to the sampling tube by a tension spring.

[0007] As an optional embodiment of the tumor sample collection device of the present invention, the inner cylinder is provided with a top cover, a bidirectional pump is installed on the top cover, the bidirectional pump is connected to the sampling tube, the sampling tube is symmetrically connected to pipes on both sides, the pipes are connected to two sets of storage tubes, a valve is installed on the sampling tube, a positioning sleeve is installed at the bottom of the inner cylinder, and the sampling tube and the positioning sleeve are connected with a clearance fit.

[0008] As an optional embodiment of the tumor sample collection device of the present invention, the top of the sleeve is provided with a side plate, and electric cylinders are symmetrically arranged on both sides of the outer side of the inner cylinder, with the telescopic rod end of the electric cylinder fixedly connected to the side plate.

[0009] As an optional embodiment of the tumor sample collection device of the present invention, wherein: a lever is fixedly connected inside the sliding sleeve, the lever has a through hole matching the sampling tube, a first rotating block is provided on the surface of the sampling tube, the lever and the first rotating block have inclined surfaces on their opposing surfaces, a sliding groove is provided inside the sliding sleeve at the sliding position of the first rotating block, a first torsion spring is connected between the first rotating block and the inner wall of the sliding sleeve, the lever moves down with the sliding sleeve, and the inclined surface pushes the first rotating block to drive the sampling tube to rotate.

[0010] As an optional embodiment of the tumor sample collection device of the present invention, wherein: a suction cup is provided on the outer surface of the sliding sleeve, and a sampling port is provided on one side of the sampling tube below the suction cup.

[0011] As an optional embodiment of the tumor sample collection device of the present invention, an inner tube is slidably installed inside the sampling tube, and scrapers are arranged in an equidistant array on the outer wall of the inner tube, with the scrapers fitting against the inner wall of the sampling tube.

[0012] As an optional embodiment of the tumor sample collection device of the present invention, the inner tube is connected to a second rotating block at its bottom end, the floater is provided with a top block at its top, the top block and the second rotating block are both provided with inclined surfaces on their opposite surfaces, the inner tube is connected to a second torsion spring at its top end, when the floater moves upward, the top block and the second rotating block press against each other and drive the inner tube to rotate in the sampling tube, and the inner tube is symmetrically provided with blocking plates on both sides, the blocking plates being positioned corresponding to the pipe connection positions.

[0013] As an optional embodiment of the tumor sample collection device of the present invention, the sleeve and the inner cylinder are provided with openings on both sides near the storage tube, the storage tube is detachably disposed in the inner cylinder, the top of the storage tube is provided with a magnetic ring, and the pipe opening is magnetically inserted into the magnetic ring.

[0014] As an optional embodiment of the tumor sample collection device of the present invention, wherein: a locking assembly is provided at the bottom of the storage tube, the locking assembly includes a fixing plate fixedly connected to the bottom of the sleeve, a top column is slidably installed inside the fixing plate, a pull rod is connected to one side of the fixing plate extending from one end of the top column, a spring is connected between the pull rod and the fixing plate, a groove is provided at the bottom of the storage tube, and the top column and the groove are fitted with a clearance.

[0015] As an optional embodiment of the tumor sample collection device of the present invention, the locking assembly further includes a sliding disk slidably connected to the storage tube, a guide rod connected to one side of the sliding disk, a sealing plate connected to the surface of the guide rod, and one end of the guide rod and one end of the top column being fitted together.

[0016] The present invention has the following beneficial effects: 1. The tumor sample collection device has a floater elastically connected inside the sampling tube by a tension spring. When the sampling tube completes the sampling, a bidirectional pump is activated to draw up the sample and simultaneously adsorb the floater. After the floater is stretched by the adsorption force, it moves to the sampling port and seals the sampling port, effectively preventing sample leakage and ensuring the integrity of the sampled tissue, thereby ensuring the accuracy of the test. 2. This tumor sample collection device improves the stability of sampling by driving the sleeve to move downward along the inner cylinder until the suction cup is fixed in the adsorption position. A push block is connected to the inner wall of the sliding sleeve and slides down along the outer wall of the sampling tube. A first rotating block is connected to the outer wall of the sampling tube. Since both the push block and the first rotating block have inclined surfaces, the push block can push the first rotating block to rotate during the downward movement of the push block, thereby driving the sampling tube to rotate. This reduces the traction during the piercing of the sampling tube, accelerates the piercing of the sampling tube, improves the sampling efficiency, and can also avoid damage during sampling. 3. The tumor sample collection device has a top block on the float and a slidingly connected inner tube inside the sampling tube. The inner tube has scrapers arranged in an equidistant array on its surface and a second rotating block at the bottom. When the float moves upward, the top block and the second rotating block press against and drive the inner tube to rotate inside the sampling tube. This process can use the rise of the float to clean the inner wall of the sampling tube in time, preventing sample loss from affecting the test results. 4. This tumor sample collection device has a magnetic ring at the top of the storage tube, which is connected to the tube by magnetic attraction. The bottom of the storage tube has a locking component. The two work together to quickly obtain the sample in the storage tube. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the three-dimensional structure of the present invention from the perspective of the front view.

[0018] Figure 2 This is a partial cross-sectional three-dimensional structural schematic diagram of the present invention.

[0019] Figure 3 This is a cross-sectional three-dimensional structural diagram of the present invention.

[0020] Figure 4 This is a cross-sectional exploded view of the sampling tube of the present invention.

[0021] Figure 5 For the present invention Figure 4 Enlarged schematic diagram of the structure at point A in the middle.

[0022] Figure 6 This is a schematic diagram of the partial cross-sectional structure viewed from below in this invention.

[0023] Figure 7 This is a schematic diagram of the locked state of the storage tube in this invention.

[0024] Figure 8 This is a schematic diagram of the unlocked state of the storage tube in this invention.

[0025] In the diagram: 1. Sleeve; 2. Electric cylinder; 3. Top cover; 4. Two-way pump; 5. Sliding sleeve; 6. Edge plate; 7. Inner cylinder; 8. Storage tube; 9. Sampling tube; 10. Valve; 11. Suction cup; 12. Pulley; 13. First rotating block; 14. First torsion spring; 15. Tension spring; 16. Floater; 17. Top block; 18. Inner tube; 19. Second rotating block; 20. Blocking plate; 21. Second torsion spring; 22. Opening; 23. Top column; 24. Pull rod; 25. Spring; 26. Fixing plate; 27. Magnetic ring; 28. Sliding disc; 29. ​​Sealing plate; 30. Guide rod; 31. Scraper; 32. Sampling port; 33. Positioning sleeve; 34. Pipeline. Detailed Implementation

[0026] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0027] Example 1, please refer to Figures 1 to 8 The present invention discloses a tumor sample collection device, including a sampling tube 9, a sampling port 32 at the bottom end of the sampling tube 9, and a sliding sleeve 5 sleeved outside the sampling tube 9. A sleeve 1 is connected to the top end of the sliding sleeve 5. An inner cylinder 7 is provided inside the sleeve 1. The sampling tube 9 extends into the inner cylinder 7. Two sets of storage tubes 8 are symmetrically arranged inside the inner cylinder 7. The storage tubes 8 and the sampling tube 9 are connected.

[0028] In this embodiment, a set of sampling tubes 9 are provided to be inserted into the tumor site until the sampling port 32 is completely inserted into the tumor to collect tumor samples. The collected samples are stored in the storage tube 8 for easy collection.

[0029] The top of the inner cylinder 7 is provided with a top cover 3, and a two-way pump 4 is installed on the top cover 3. The two-way pump 4 is connected to the sampling tube 9. The sampling tube 9 is symmetrically connected to pipes 34 on both sides. The pipes 34 are connected to two sets of storage tubes 8. A valve 10 is installed on the sampling tube 9. A positioning sleeve 33 is installed at the bottom of the inner cylinder 7. The sampling tube 9 and the positioning sleeve 33 are connected with a clearance fit.

[0030] In this embodiment, a bidirectional pump 4 is installed on the top cover 3 at the top of the inner cylinder 7. The bidirectional pump 4 is connected to the sampling tube 9. After the sample is drawn in, the valve 10 is closed, and then the sample is sent into the storage tube 8 by negative pressure to complete the tumor sample collection.

[0031] It should be noted that the bidirectional pump 4 achieves liquid suction and pressurization through mechanical energy conversion, specifically including: Liquid suction: by generating a vacuum or pressure difference through impeller rotation or piston movement, the liquid is sucked into the pump from a low position; Liquid pressurization: through kinetic energy conversion and pressure chamber design, the liquid is given pressure energy, and the sample sucked into the sampling tube 9 is pressed into the storage tube 8 through negative pressure.

[0032] Example 2 is an explanation based on Example 1. For details, please refer to [link / reference]. Figures 1 to 8 The top of the sleeve 1 is provided with a side plate 6, and electric cylinders 2 are symmetrically arranged on both sides of the outer side of the inner cylinder 7. The telescopic rod end of the electric cylinder 2 is fixedly connected to the side plate 6, and a suction cup 11 is provided on the outer surface of the sliding sleeve 5.

[0033] In this embodiment, a side plate 6 is provided on the top of the sleeve 1, and an electric cylinder 2 is connected to the outside of the inner cylinder 7. The telescopic rod of the electric cylinder 2 is connected to the side plate 6. When the electric cylinder 2 is activated, the sleeve 1 can be moved downward along the inner cylinder 7 until the suction cup 11 is fixed in the adsorption position, which is used to improve the stability during sampling.

[0034] A lever 12 is fixedly connected inside the sliding sleeve 5. The lever 12 has a through hole that matches the sampling tube 9. The surface of the sampling tube 9 is provided with a first rotating block 13. The opposing surfaces of the lever 12 and the first rotating block 13 are both provided with inclined surfaces. A sliding groove is provided inside the sliding sleeve 5 at the sliding position of the first rotating block 13. A first torsion spring 14 is connected between the first rotating block 13 and the inner wall of the sliding sleeve 5. The lever 12 moves down with the sliding sleeve 5 and uses the inclined surfaces to push the first rotating block 13 to drive the sampling tube 9 to rotate.

[0035] In this embodiment, a lever 12 is connected to the inner wall of the sliding sleeve 5. The lever 12 slides down the outer wall of the sampling tube 9. A first rotating block 13 is connected to the outer wall of the sampling tube 9. Since both the lever 12 and the first rotating block 13 have inclined surfaces, during the downward movement of the lever 12, the lower point of the lever 12 pushes the higher point of the first rotating block 13. When the downward pressure is greater than the resistance force, the lever 12 can push the first rotating block 13 to rotate, thereby driving the sampling tube 9 to rotate. This reduces the pulling during the piercing process of the sampling tube 9, accelerates the piercing of the sampling tube 9, improves the sampling efficiency, and can also avoid damage caused by sampling.

[0036] Example 3 is an explanation based on Example 1. For details, please refer to [link / reference]. Figures 1 to 8 A floater 16 is installed inside the sampling tube 9 below the horizontal position of the sampling port 32. The floater 16 is slidably connected to the sampling tube 9 by a tension spring 15.

[0037] In this embodiment, a float 16 is elastically connected inside the sampling tube 9 via a tension spring 15. When the sampling tube 9 completes sampling, the bidirectional pump 4 is activated to draw up the sample, and at the same time, it can also adsorb the float 16. After the float 16 is stretched by the adsorption force, it moves to the sampling port 32 and seals the sampling port 32, effectively preventing the sample from flowing out and leaking, ensuring the integrity of the sampled tissue, and thus ensuring the accuracy of the detection.

[0038] Example 4 is an explanation based on Example 1. For details, please refer to [link / reference]. Figures 1 to 8 An inner tube 18 is slidably installed inside the sampling tube 9. Scraper blades 31 are arranged in an equidistant array on the outer wall of the inner tube 18, and the scraper blades 31 are in contact with the inner wall of the sampling tube 9. A second rotating block 19 is connected to the bottom end of the inner tube 18. A top block 17 is provided on the top of the floater 16. The top block 17 and the second rotating block 19 are both provided with inclined surfaces on their opposite surfaces. A second torsion spring 21 is connected to the top end of the inner tube 18.

[0039] In this embodiment, a top block 17 is provided on the floater 16, and an inner tube 18 is provided in the sampling tube 9. The inner tube 18 has scrapers 31 arranged in annular equidistant array on its surface, and a second rotating block 19 is provided at the bottom of the inner tube 18. When the floater 16 moves upward, the top block 17 and the second rotating block 19 press against and drive the inner tube 18 to rotate in the sampling tube 9. This process can use the rise of the floater 16 to clean the inner wall of the sampling tube 9 in time. The cleaned sample is adsorbed by the bidirectional pump 4 and finally enters the storage tube 8.

[0040] The inner pipe 18 is symmetrically provided with blocking plates 20 on both sides, and the positions of the blocking plates 20 correspond to the positions where the pipe 34 is connected.

[0041] It should be noted that the initial position of the blocking plate 20 is to block the connection between the pipe 34 and the sampling tube 9. The inner tube 18 is lifted by the floater 16 and rotated 90°, which opens the pipe 34 and allows the sample to be sucked into the storage tube 8.

[0042] Example 4 is an explanation based on Example 1. For details, please refer to [link / reference]. Figures 1 to 8 Both the sleeve 1 and the inner cylinder 7 have openings 22 on both sides near the storage tube 8. The storage tube 8 is detachably installed inside the inner cylinder 7. A magnetic ring 27 is installed at the top of the storage tube 8, and the pipe opening 34 is magnetically inserted into the magnetic ring 27. A locking assembly is installed at the bottom of the storage tube 8. The locking assembly includes a fixing plate 26 fixedly connected to the bottom of the sleeve 1. A top post 23 is slidably installed inside the fixing plate 26. One end of the top post 23 extends to one side of the fixing plate 26 and is connected to a pull rod 24. A spring 25 is connected between the pull rod 24 and the fixing plate 26. A groove is opened at the bottom of the storage tube 8, and the top post 23 and the groove are fitted with a clearance. The locking assembly also includes a sliding disc 28 slidably connected inside the storage tube 8. A guide rod 30 is connected to one side of the sliding disc 28. A sealing plate 29 is connected to the surface of the guide rod 30. One end of the guide rod 30 is fitted against one end of the top post 23.

[0043] In this embodiment, the storage tube 8 is detachably installed inside the inner cylinder 7. When the sample in the storage tube 8 has been collected to the required dose, the baffle outside the opening 22 can be opened and the storage tube 8 can be taken out.

[0044] Specifically, a magnetic ring 27 is provided at the top of the storage tube 8. The magnetic ring 27 and the pipe 34 are magnetically attracted to facilitate connection. A locking component is provided at the bottom of the storage tube 8. In the initial state, the sliding disc 28 and the guide rod 30 slide in a sealed manner inside the storage tube 8. Pressing down the top column 23 can put the storage tube 8 into the inner cylinder 7. The top column 23 pushes into the bottom of the storage tube 8, and the magnetic ring 27 can make the storage tube 8 stable. When the sample in the storage tube 8 reaches a certain dose, the sliding disc 28 is pressed down, and the sliding disc 28 drives the guide rod 30 to move down, which is enough to push the top column 23 out of the bottom of the storage tube 8, so that the top column 23 and the storage tube 8 are separated. At this time, the opening 22 can be opened to take out the storage tube 8, and the sample in the storage tube 8 can be quickly obtained.

[0045] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, goods, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, goods, or apparatus.

[0046] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A tumor sample collection device, comprising a sampling tube (9), characterized in that: It also includes a sliding sleeve (5) sleeved outside the sampling tube (9), the top of the sliding sleeve (5) is connected to a sleeve (1), an inner cylinder (7) is provided inside the sleeve (1), the sampling tube (9) extends into the inner cylinder (7), two sets of storage tubes (8) are symmetrically arranged inside the inner cylinder (7), and the storage tubes (8) and the sampling tube (9) are connected. The sampling tube (9) has a sampling port (32) at the bottom end, and a float (16) is provided inside the sampling tube (9) below the horizontal position of the sampling port (32). The float (16) is slidably connected to the sampling tube (9) by a tension spring (15). The inner cylinder (7) is provided with a top cover (3), and a two-way pump (4) is installed on the top cover (3). The two-way pump (4) is connected to the sampling tube (9). The sampling tube (9) is symmetrically connected to pipes (34) on both sides. The pipes (34) are connected to two sets of storage tubes (8). A valve (10) is installed on the sampling tube (9). A positioning sleeve (33) is installed at the bottom of the inner cylinder (7). The sampling tube (9) and the positioning sleeve (33) are connected with a clearance fit. A lever (12) is fixedly connected inside the sliding sleeve (5). The lever (12) has a through hole that matches the sampling tube (9). The sampling tube (9) has a first rotating block (13) on its surface. The lever (12) and the first rotating block (13) have inclined surfaces on their opposite sides. The sliding sleeve (5) has a sliding groove located at the sliding position of the first rotating block (13). A first torsion spring (14) is connected between the first rotating block (13) and the inner wall of the sliding sleeve (5). The lever (12) moves down with the sliding sleeve (5) and uses the inclined surface to push the first rotating block (13) to drive the sampling tube (9) to rotate. An inner tube (18) is slidably installed inside the sampling tube (9). The outer wall of the inner tube (18) is arranged in a ring with scrapers (31) at equal intervals. The scrapers (31) are in contact with the inner wall of the sampling tube (9). The bottom end of the inner tube (18) is connected to a second rotating block (19), the top of the float (16) is provided with a top block (17), the top block (17) and the second rotating block (19) are both provided with inclined surfaces, the top end of the inner tube (18) is connected to a second torsion spring (21), when the float (16) moves upward, the top block (17) and the second rotating block (19) press and drive the inner tube (18) to rotate in the sampling tube (9), the inner tube (18) is symmetrically provided with blocking plates (20) on both sides, and the blocking plate (20) is positioned in a position corresponding to the connection position of the pipe (34).

2. The tumor sample collection device according to claim 1, characterized in that: The top of the sleeve (1) is provided with a side plate (6), and electric cylinders (2) are symmetrically arranged on both sides of the outer side of the inner cylinder (7). The telescopic rod end of the electric cylinder (2) is fixedly connected to the side plate (6).

3. The tumor sample collection device according to claim 1, characterized in that: The outer surface of the sliding sleeve (5) is provided with a suction cup (11), and a sampling port (32) is opened on one side of the sampling tube (9) below the suction cup (11).

4. The tumor sample collection device according to claim 1, characterized in that: Both the sleeve (1) and the inner cylinder (7) have openings (22) on both sides near the storage tube (8). The storage tube (8) is detachably installed inside the inner cylinder (7). A magnetic ring (27) is installed on the top of the storage tube (8). The pipe (34) is magnetically inserted into the magnetic ring (27).

5. A tumor sample collection device according to claim 4, characterized in that: The storage tube (8) is provided with a locking assembly at the bottom. The locking assembly includes a fixing plate (26) fixedly connected to the bottom of the sleeve (1). A top post (23) is slidably installed inside the fixing plate (26). One end of the top post (23) extends to one side of the fixing plate (26) and is connected to a pull rod (24). A spring (25) is connected between the pull rod (24) and the fixing plate (26). A groove is provided at the bottom of the storage tube (8). The top post (23) and the groove are fitted with a clearance.

6. A tumor sample collection device according to claim 5, characterized in that: The locking assembly also includes a sliding disc (28) slidably connected to the storage tube (8). A guide rod (30) is connected to one side of the sliding disc (28). A sealing plate (29) is connected to the surface of the guide rod (30). One end of the guide rod (30) and one end of the top column (23) are fitted together.

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