Preparation method of natural multi-layer anti-allergic garment fabric and garment

Abstract

The invention relates to the technical field of multi-layer fabrics, in particular to a preparation method of a natural multi-layer anti-allergic garment fabric and a garment. Comprising the following steps: preparing propylene glycol alginate-sitosterol microcapsules, preparing an isosorbide-sodium alginate cross-linked body, and preparing the natural multi-layer anti-allergic garment fabric. According to the invention, the propylene glycol alginate and the beta-sitosterol are prepared into microcapsules, the microcapsules are used on the anti-allergy coating of the fabric, the microcapsules as phytosterol and beta-sitosterol can inhibit cells from releasing histamine so as to reduce skin anaphylaxis, and the polysaccharide structure of the propylene glycol alginate can also form a certain physical barrier, so that the anti-allergy effect of the fabric is improved. The anti-allergy garment material has the advantages that the anti-allergy garment material can be applied to the garment material, direct contact between external irritants or other components and skin can be reduced, allergy risks can be reduced, amphiphilic networks can be constructed by the beta-sitosterol and the propylene glycol alginate, accordingly, microencapsulation embedding can be realized, the sitosterol can be prevented from being layered or crystallized and separated out due to density difference, and anti-allergy effects of the garment material can be prolonged.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of multi-layer fabric, and particularly relates to a preparation method of natural multi-layer anti-allergy garment fabric and a garment. BACKGROUND

[0002] With the improvement of people's demand for health and quality of life, the demand for functional textiles is increasing, especially the garment fabric with the characteristics of waterproof and breathable, such as medical protective clothing. The medical protective clothing needs to block the liquid containing pathogens such as blood, droplets and secretions, so as to avoid the transmission of viruses and bacteria through liquid contact. However, medical staff often wear protective clothing for a long time, and the wearing time can even exceed 8 hours. Low-sensitivity or anti-allergy fabric can reduce the problem of skin itching and swelling.

[0003] However, the traditional waterproof coating may contain formaldehyde or fluorine compounds, and long-term contact may cause contact dermatitis or allergic reactions. In order to have both waterproof and anti-allergy functions, in addition to coating a waterproof coating, an anti-allergy agent will also be added to the fabric. The existing natural anti-allergy agent such as beta-sitosterol faces the problems of low loading rate and easy loss in the application of textiles. This is because beta-sitosterol is a hydrophobic substance and is insoluble in water, but only soluble in organic solvents such as chloroform and diethyl ether. The surface of textile fibers such as cotton and polyester fabric contains hydroxyl or carboxyl groups, which are mostly hydrophilic. It is difficult for them to adsorb each other, thereby reducing the effective loading rate. It can be seen that a single coating cannot meet the collaborative needs of anti-allergy, waterproof and moisture permeability. When multiple layers are combined, the interface bonding force is insufficient, which may cause delamination failure. Therefore, it is urgent to develop a fully natural and multifunctional integrated garment fabric to achieve the dynamic balance of anti-allergy, waterproof and breathable through layered design, while avoiding the irritation of chemical residues to the skin. The present application provides a preparation method of natural multi-layer anti-allergy garment fabric and a garment to solve the problems existing in the prior art. SUMMARY

[0004] In view of the deficiencies in the prior art, the purpose of the present application is to provide a preparation method of natural multi-layer anti-allergy garment fabric and a garment.

[0005] A preparation method of natural multi-layer anti-allergy garment fabric, characterized in that the natural multi-layer anti-allergy garment fabric is prepared by combining an anti-allergy coating coated on the lower side of a cotton fiber fabric layer, the cotton fiber fabric layer and a waterproof coating coated on the upper side of the cotton fiber fabric layer. The anti-allergy coating is a coating composed of alginate propylene glycol ester-sitosterol microcapsules, water-based polyurethane and deionized water. The waterproof coating is a coating composed of isosorbide-sodium alginate crosslinking body, chitosan solution, glycerol and deionized water. The cotton fiber fabric layer is a cloth woven from cotton fiber threads.

[0006] Further, the preparation method of the alginate propylene glycol ester-sitosterol microcapsule comprises the following steps: S1.1: 0.1-0.3 parts by mass of β-sitosterol is added to 10-12 parts by mass of anhydrous ethanol, and the temperature is raised to 60-65°C; 1-2% of Tween 80 by mass of the system is added at a rotation speed of 200-250 r / min, and then ultrasonic treatment is carried out at 300-320 W for 10-15 min to obtain a β-sitosterol emulsion; S1.2: 2-3 parts by mass of alginate propylene glycol ester is added to 80-85 parts by mass of deionized water, and the temperature is raised to 50-55°C; stirring is carried out at a rotation speed of 500-550 r / min for 1-1.5 h to obtain an alginate propylene glycol ester solution; the β-sitosterol emulsion and the alginate propylene glycol ester solution are mixed, and then 1-2% of polyvinyl alcohol by mass of the system is added; 0.3-0.5% of a calcium chloride solution by mass of the system is added dropwise, and stirring is carried out at a rotation speed of 1000-1100 r / min by a magnetic stirrer for 30-35 min; then the product is filtered and washed with deionized water, and drying is carried out at 80-85°C for 24-25 h to obtain alginate propylene glycol ester-sitosterol microcapsules.

[0007] Further, the preparation method of the isosorbide-sodium alginate crosslinking body comprises the following steps: S2.1: Isosorbide polyurethane is dissolved in anhydrous dimethyl sulfoxide (10% w / v), and 1.2 times the molar amount of hexamethylene diisocyanate is added; reaction is carried out at 60-65°C for 2-2.5 h while being protected by nitrogen to obtain a capped isosorbide polyurethane solution; S2.2: Sodium alginate solid is dissolved in MES buffer at a solid-liquid ratio of 1 g: (50-55) mL, and ultrasonic defoaming is carried out for 30-35 min to obtain a sodium alginate solution; S2.3: 1-2 parts by mass of the sodium alginate solution, 0.2-0.4 parts by mass of EDC, and 0.1-0.2 parts by mass of NHS are mixed and stirred at room temperature 22-24°C for 30-35 min to activate, and the pH value is maintained at 5.5-6; then an equal volume of the capped isosorbide polyurethane solution is added dropwise, the temperature is raised to 50-55°C, and magnetic stirring is carried out at a rotation speed of 200-300 r / min under nitrogen protection for 6-6.5 h; after stirring is completed, 0.1M glycine is added to quench the reaction; the reaction product is dialyzed with deionized water for 72-74 h, and freeze-drying is carried out to obtain an isosorbide-sodium alginate crosslinking body.

[0008] Further, the preparation method of the natural multi-layer anti-allergy garment fabric comprises the following steps: S3.1: 10-20% of propylene glycol alginate-sitosterol microcapsules, 30-35% of aqueous polyurethane and deionized water as the balance are dispersed under ultrasonic treatment at 20 kHz for 10-15 min, and the pH value is adjusted to 6-7 to obtain an anti-allergy layer coating, then, the cotton fiber fabric is coated with the anti-allergy layer coating by a coating machine with one side of the cotton fiber fabric facing up, and the wet film thickness is controlled to be 100-110 mu m, then, pre-drying is performed at 80-85 DEG C for 3-4 min, and drying is performed at 150-155 DEG C for 2-3 min to obtain the cotton fiber fabric coated with the anti-allergy layer; S3.2: 15-18% of isosorbide-sodium alginate crosslinking body, 2-3% of chitosan solution, 3-4% of glycerol and deionized water as the balance are reacted at 50-55 DEG C for 2-2.5 h to obtain a waterproof layer coating, and the cotton fiber fabric coated with the anti-allergy layer is coated with the waterproof layer coating by a roll coating machine, and then, the cotton fiber fabric is immersed in a calcium chloride solution for 30-35 s after hot air drying at 60-65 DEG C for 10-15 min, and then, the cotton fiber fabric is dried again at 60-65 DEG C for 10-15 min to obtain the natural multi-layer anti-allergic clothing fabric.

[0009] Further, the volume ratio of isosorbide polyurethane to anhydrous dimethyl sulfoxide is 1: (9-10).

[0010] Further, the concentration of the calcium chloride solution is 0.1-0.15 M.

[0011] Further, the concentration of the chitosan solution is 10-15 g / L.

[0012] A clothing made of the natural multi-layer anti-allergic clothing fabric prepared by the preparation method of the natural multi-layer anti-allergic clothing fabric.

[0013] The present application has the following advantages: 1. In the present application, propylene glycol alginate and beta-sitosterol are prepared into microcapsules and used in the anti-allergic coating of the fabric, as a phytosterol, beta-sitosterol can inhibit the release of histamine from cells, thereby reducing the skin allergic reaction, and the polysaccharide structure of propylene glycol alginate can also form a certain physical barrier to reduce the direct contact of external irritants or other components with the skin and reduce the risk of allergy, meanwhile, the hydrophobic steroidal structure of beta-sitosterol can be inserted into the hydrophobic region of propylene glycol alginate, the combination is enhanced through van der Waals force, the hydrophilic alginate backbone of propylene glycol alginate provides water solubility, and the esterification side chain forms a micro area phase separation with sitosterol to construct an amphiphilic network, thereby realizing microencapsulation embedding, preventing sitosterol from being layered or crystallized due to density difference, and prolonging the anti-allergic effect of the clothing fabric.

[0014] 2、The present application forms a crosslinked body by crosslinking isosorbide polyurethane and sodium alginate, and the isosorbide polyurethane is reacted with hexamethylene diisocyanate in dimethyl sulfoxide to form a high-activity group at the end, which is convenient for subsequent reaction with the group of sodium alginate to form an activated chemical bond, such as an amide bond or a urethane bond, and a three-dimensional network structure is formed by bonding, while retaining the natural antibacterial property of sodium alginate, preventing the occurrence of isocyanate groups in the crosslinking reaction, making the three-dimensional network structure very stable, preventing water molecules from penetrating, and reducing the water vapor diffusion coefficient, thereby achieving the effect of bringing waterproof capability to the garment fabric.

[0015] 3、The present application coats the front of the cotton fiber garment fabric with a coating containing alginate propylene glycol ester-stigmasterol microcapsules, and coats the back with a coating containing isosorbide-sodium alginate crosslinked body, and the two components do not affect each other when coating, and have a synergistic effect on cotton fiber after coating is completed, the carboxyl and hydroxyl groups of sodium alginate form hydrogen bonds with the hydroxyl groups of cotton fiber, enhancing the adhesion of the coating, the propylene glycol ester groups of alginate propylene glycol ester combine with the microporous structure of cotton fiber, optimizing the air permeability-waterproof balance, at the same time, the outer layer of sodium alginate contacts water and prevents water penetration by water absorption, when too much water penetrates through the cotton fiber to the inner layer, the alginate propylene glycol ester of the inner layer shrinks due to hydrophobicity, forming a one-way moisture channel, and the inner layer moisture is guided back to the cotton fiber, avoiding direct moisture permeation of the fabric when the humidity is too high, and alginate propylene glycol ester, sodium alginate and isosorbide are all natural materials converted to obtain, and the preparation of the multi-layer garment fabric has the four advantages of anti-allergy, waterproof, breathable and environmental protection. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 The preparation method of the natural multi-layer anti-allergic garment fabric of the present application is shown in the flow chart. DETAILED DESCRIPTION

[0017] In order to enable personnel in the technical field to better understand the technical solutions in the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in combination with the drawings in the embodiments of the present application. EMBODIMENT

[0018] A preparation method of a natural multi-layer anti-allergic garment fabric, as shown in Figure 1 The preparation method of the natural multi-layer anti-allergic garment fabric of the present application is shown in the flow chart. S1: Preparation of alginate propylene glycol ester-stigmasterol microcapsules S1.1: 0.1 parts by mass of β-stigmasterol is added to 10 parts by mass of anhydrous ethanol, heated to 60℃, and 1% of Tween 80 by mass of the system is added at a rotation speed of 200r / min, followed by ultrasonic treatment at 300W for 10min to obtain a β-stigmasterol emulsion; S1.2: 2 parts by mass of propylene glycol alginate was added to 80 parts by mass of deionized water, heated to 50°C, and stirred at a speed of 500 r / min for 1 h to obtain a propylene glycol alginate solution. The β-sitosterol emulsion was mixed with the propylene glycol alginate solution, and then 1% of polyvinyl alcohol based on the mass of the system was added. Then, 0.3% of a calcium chloride solution based on the mass of the system was added dropwise, and stirred at a speed of 1000 r / min using a magnetic stirrer for 30 min. Subsequently, the product was filtered and washed with deionized water, and dried at 80°C for 24 h to obtain propylene glycol alginate-sitosterol microcapsules.

[0019] S2: Preparation of isosorbide-sodium alginate crosslinker S2.1: Isosorbide polyurethane was dissolved in anhydrous dimethyl sulfoxide, and the volume ratio of isosorbide polyurethane to anhydrous dimethyl sulfoxide was 1:9. The solution was reacted at 60°C for 2 h under nitrogen protection to obtain a capped isosorbide polyurethane solution; S2.2: Sodium alginate solid was dissolved in MES buffer at a solid-to-liquid ratio of 1 g: 50 mL, and ultrasonic defoaming was performed for 30 min to obtain a sodium alginate solution; S2.3: 1 part by mass of the sodium alginate solution, 0.2 parts by mass of EDC, and 0.1 parts by mass of NHS were mixed and stirred at room temperature for 30 min to activate, and the pH value was maintained at 5.5. Subsequently, an equal volume of the capped isosorbide polyurethane solution was added dropwise, heated to 50°C, and stirred at a speed of 200 r / min under nitrogen protection for 6 h. After stirring, 0.1M glycine was added to quench the reaction, and the reaction product was dialyzed against deionized water for 72 h, and then freeze-dried to obtain an isosorbide-sodium alginate crosslinker.

[0020] S3: Preparation of natural multi-layer anti-allergy garment fabric S3.1: 10% of propylene glycol alginate-sitosterol microcapsules, 30% of waterborne polyurethane, and deionized water as the balance were dispersed under ultrasonic treatment at 20 kHz for 10 min, and the pH value was adjusted to 6 to obtain an anti-allergy layer coating. Subsequently, one side of the cotton fiber fabric was coated with the anti-allergy layer coating by a coating machine, and the wet film thickness was controlled at 100 μm. Subsequently, the fabric was pre-dried at 80°C for 3 min, and then dried at 150°C for 2 min to obtain cotton fiber fabric coated with an anti-allergy layer; S3.2: 15% of isosorbide-sodium alginate crosslinker, 2% of chitosan solution with a concentration of 10 g / L, 3% of glycerol, and deionized water as the balance were reacted at 50°C for 2 h to obtain a waterproof layer coating. The cotton fiber fabric coated with the anti-allergy layer was coated with the waterproof layer coating by a roll coater. After hot air drying at 60°C for 10 min, the fabric was immersed in a 0.1M calcium chloride solution for 30 s, and then dried at 60°C for another 10 min to obtain a natural multi-layer anti-allergy garment fabric. Example

[0021] A method for preparing a natural multi-layered hypoallergenic clothing fabric, such as Figure 1 As shown, it includes the following steps: S1: Preparation of propylene glycol alginate-sitosterol microcapsules S1.1: Add 0.1 parts by weight of β-sitosterol to 10 parts by weight of anhydrous ethanol, heat to 65°C, add 1% by weight of Tween 80 at 250 r / min, and then sonicate at 300 W for 15 min to obtain β-sitosterol emulsion. S1.2: Add 2 parts by mass of propylene glycol alginate to 80 parts by mass of deionized water, heat to 55℃ and stir at 550 r / min for 1.5 h to obtain a propylene glycol alginate solution. Mix β-sitosterol emulsion with the propylene glycol alginate solution and then add 1% by mass of polyvinyl alcohol, followed by 0.3% by mass of calcium chloride solution. Stir with a magnetic stirrer at 1100 r / min for 35 min. Then filter the product, wash with deionized water, and dry at 85℃ for 25 h to obtain propylene glycol alginate-sitosterol microcapsules.

[0022] S2: Preparation of isosorbide-sodium alginate cross-linker S2.1: Dissolve isosorbide polyurethane in anhydrous dimethyl sulfoxide at a volume ratio of 1:9, react at 65°C for 2.5 h, and simultaneously under nitrogen protection to obtain a capped isosorbide polyurethane solution. S2.2: Dissolve sodium alginate solid in MES buffer at a material-to-liquid ratio of 1g:50mL, and degas by sonication for 35min to obtain sodium alginate solution; S2.3: Mix 1 part by mass of sodium alginate solution, 0.2 parts by mass of EDC and 0.1 parts by mass of NHS and stir at room temperature (24℃) for 35 min while maintaining the pH at 6. Then, add an equal volume of end-capped isosorbide polyurethane solution, heat to 55℃, and magnetically stir at 300 r / min for 6.5 h under nitrogen protection. After stirring, add 0.1 M glycine until the reaction is quenched. Dialyze the reaction product with deionized water for 74 h and freeze-dry to obtain isosorbide-sodium alginate crosslinker.

[0023] S3: Preparation of natural multi-layered hypoallergenic clothing fabric S3.1: 10% of propylene glycol alginate-stigmasterol microcapsules, 30% of aqueous polyurethane and deionized water as the balance were dispersed under ultrasonic treatment at 20 kHz for 15 min, and the pH value was adjusted to 7 to obtain an anti-allergy layer coating, then the cotton fiber fabric was coated with the anti-allergy layer coating by a coating machine with one side of the cotton fiber fabric facing up, and the wet film thickness was controlled at 110 μm, then pre-drying was performed at 85°C for 4 min, and drying was performed at 155°C for 3 min to obtain the cotton fiber fabric coated with the anti-allergy layer; S3.2: 15% of isosorbide-sodium alginate crosslinker, 2% of a chitosan solution with a concentration of 10 g / L, 3% of glycerol and deionized water as the balance were reacted at 55°C for 2.5 h to obtain a waterproof layer coating, and the cotton fiber fabric coated with the anti-allergy layer was coated with the waterproof layer coating by a roll coater, and then immersed in a 0.15M calcium chloride solution for 35 s after hot air drying at 65°C for 15 min, and then secondarily dried at 65°C for 15 min to obtain the natural multi-layer anti-allergic clothing fabric. Embodiment

[0024] A preparation method of a natural multi-layer anti-allergic clothing fabric, as shown in Figure 1 , comprises the following steps: S1: preparing propylene glycol alginate-stigmasterol microcapsules S1.1: 0.3 parts by mass of β-stigmasterol was added to 12 parts by mass of anhydrous ethanol, heated to 60°C, and then 2% of Tween 80 based on the mass of the system was added at a rotation speed of 200 r / min, followed by ultrasonic treatment at 320 W for 10 min to obtain a β-stigmasterol emulsion; S1.2: 3 parts by mass of propylene glycol alginate was added to 85 parts by mass of deionized water, heated to 50°C, and stirred at a rotation speed of 500 r / min for 1 h to obtain a propylene glycol alginate solution, then the β-stigmasterol emulsion and the propylene glycol alginate solution were mixed, 2% of polyvinyl alcohol based on the mass of the system was further added, and 0.5% of a calcium chloride solution based on the mass of the system was added dropwise, and stirred at a rotation speed of 1000 r / min for 30 min by a magnetic stirrer, then the product was filtered and washed with deionized water, and dried at 80°C for 24 h to obtain propylene glycol alginate-stigmasterol microcapsules.

[0025] S2: preparing isosorbide-sodium alginate crosslinker S2.1: isosorbide polyurethane was dissolved in anhydrous dimethyl sulfoxide, and the volume ratio of isosorbide polyurethane to anhydrous dimethyl sulfoxide was 1:9, and the solution was reacted at 60°C for 2 h while being protected by nitrogen to obtain a capped isosorbide polyurethane solution; S2.2: sodium alginate solid was dissolved in MES buffer at a solid-liquid ratio of 1 g: 55 mL, and ultrasonic defoaming was performed for 30 min to obtain a sodium alginate solution; S2.3: 2 parts by mass of sodium alginate solution, 0.4 parts by mass of EDC and 0.2 parts by mass of NHS were mixed and activated at room temperature 22℃ for 35 min with stirring, and the pH value was kept at 5.5, then an equal volume of blocked isosorbide polyurethane solution was added dropwise, the temperature was raised to 50℃, and magnetic stirring was carried out at 200 r / min under nitrogen protection for 6 h. After stirring, 0.1 M glycine was added to quench the reaction, and the reaction product was dialyzed against deionized water for 72 h, and then freeze-dried to obtain isosorbide-sodium alginate crosslinker.

[0026] S3: Preparation of natural multi-layer anti-allergic clothing fabric S3.1: 20% of propylene glycol alginate-β-sitosterol microcapsules, 35% of aqueous polyurethane and deionized water as the balance were dispersed under ultrasonic treatment at 20 kHz for 10 min, and the pH value was adjusted to 6 to obtain an anti-allergic layer coating. Then, the cotton fiber fabric was coated with the anti-allergic layer coating by a coating machine with one side facing up, and the wet film thickness was controlled at 100 μm. Then, pre-drying was carried out at 80℃ for 3 min, and drying was carried out at 150℃ for 2 min to obtain cotton fiber fabric coated with an anti-allergic layer. S3.2: 18% of isosorbide-sodium alginate crosslinker, 3% of chitosan solution with a concentration of 15 g / L, 4% of glycerol and deionized water as the balance were reacted at 50℃ for 2 h to obtain a waterproof layer coating. The cotton fiber fabric coated with an anti-allergic layer was coated with the waterproof layer coating by a roll coater, and then hot air drying was carried out at 60℃ for 10 min. Then, the fabric was immersed in a 0.1 M calcium chloride solution for 30 s, and then secondary drying was carried out at 60℃ for 10 min to obtain a natural multi-layer anti-allergic clothing fabric.

[0027] Comparative Example 1 Comparative Example 1 is different from Example 1 in that no propylene glycol alginate is added in step S1.2, and the remaining steps are unchanged, which is denoted as Comparative Example 1.

[0028] Comparative Example 2 Comparative Example 2 is different from Example 1 in that step S1.1 is not performed, and no β-sitosterol emulsion is added in step S1.2, and the remaining steps are unchanged, which is denoted as Comparative Example 2.

[0029] Comparative Example 3 Comparative Example 3 is different from Example 1 in that step S2.2 is not performed, and no sodium alginate solution is added in step S2.3, and the remaining steps are unchanged, which is denoted as Comparative Example 3.

[0030] Comparative Example 4 Comparative Example 4 is different from Example 1 in that step S2.1 is not performed, and no blocked isosorbide polyurethane solution is added in step S2.3, and the remaining steps are unchanged, which is denoted as Comparative Example 4.

[0031] Comparative Example 5: Comparative Example 5 is a cotton fiber fabric coated with only the anti-allergic layer coating compared with Example 1.

[0032] Comparative Example 6: Comparative Example 6 is a cotton fiber fabric coated with only the waterproof layer coating compared with Example 1.

[0033] Comparative Example 7: Comparative Example 7 is a commercially available anti-allergic waterproof fabric.

[0034] The sensitivities of Examples 1-3 and Comparative Examples 1-2, 5-7 were tested using the method in GB / T 16886.10-2017 “Biological evaluation of medical devices Part 10: Tests for irritation and skin sensitization” as shown in Table 1.

[0035] The waterproof grades of Examples 1-3 and Comparative Examples 3-7 were evaluated using GB / T 4744-2013 as shown in Table 2.

[0036] Table 1 Primary skin irritation index Pll Example 1 0.1 Example 2 0.1 Example 3 0.1 Comparative Example 1 0.7 Comparative Example 2 0.8 Comparative Example 5 0.3 Comparative Example 6 0.8 Comparative Example 7 0.3 Table 2 Hydrostatic pressure value (kPa) Rank Example 1 34 Grade 3 Example 2 36 Grade 3 Example 3 35 Grade 3 Comparative Example 3 17 Grade 2 Comparative Example 4 16 Grade 2 Comparative Example 5 8 Grade 1 Comparative Example 6 24 Grade 3 Comparative Example 7 23 Grade 3 As can be seen from Table 1, Examples 1-3 as a complete process with only changing part of the experimental parameters, the PII values are all 0.1, indicating that the sensitization is very low, and it can be seen that the raw material combination of the present application can significantly reduce skin irritation. Comparative Example 1 lacks propylene glycol alginate, and the PII rises to 0.7, and Comparative Example 2 lacks β-sitosterol emulsion, and the PII reaches 0.8, indicating that β-sitosterol emulsion and propylene glycol alginate have an effect on anti-allergic effect, and the combination of the two has a synergistic better effect, and the PII of Comparative Example 5 is only 0.3, which is better than Comparative Examples 1-2, but higher than Examples 1-3, proving that the synergy of anti-allergic layer + waterproof layer can further reduce the sensitization, and the PII of Comparative Example 6 is as high as 0.8, close to Comparative Example 2, indicating that the waterproof layer alone may introduce a risk of sensitization, which needs to be neutralized by the anti-allergic layer, and the PII of Comparative Example 7 is 0.3, but the sensitivities of Examples 1-3 are lower, and it can be seen that the raw material combination of the present application has better anti-allergic effect.

[0037] As can be seen from Table 2, the hydrostatic pressure values of Examples 1-3 are 34-36 kPa, reaching 3-level waterproofing, indicating that the complete process can effectively build a dense waterproof layer. The hydrostatic pressure of Comparative Example 3 drops to 17 kPa, 2-level; the hydrostatic pressure of Comparative Example 4 is only 16 kPa, 2-level, indicating that single end-capped isosorbide polyurethane or sodium alginate does not have good waterproof performance; the hydrostatic pressure of Comparative Example 5, which is only the anti-allergy layer, is only 8 kPa, 1-level, almost without waterproof function, confirming that the anti-allergy layer alone cannot provide waterproofness, the hydrostatic pressure of Comparative Example 6, which is only the waterproof layer, is 24 kPa, 3-level, and the hydrostatic pressure of Comparative Example 7, which is a commercially available fabric, is 23 kPa, 3-level. The hydrostatic pressure values of Examples 1-3 are higher, and the waterproofness is better, reflecting the technical leading nature of the process.

[0038] It should be understood that, for those skilled in the art, improvements or changes can be made according to the above description, and all these improvements and changes shall belong to the protection scope of the appended claims of the present application. The parts not described in detail in the specification belong to the prior art known to those skilled in the art.

Claims

1. A method for preparing a natural multilayer anti-allergic apparel fabric, characterized by, The natural multi-layer anti-allergic clothing fabric is prepared by combining an anti-allergic coating coated on the lower side of a cotton fiber fabric layer, the cotton fiber fabric layer and a waterproof coating coated on the upper side of the cotton fiber fabric layer; The anti-allergic coating is a coating composed of alginate propylene glycol ester-stigmasterol microcapsules, water-based polyurethane and deionized water; the waterproof coating is a coating composed of isosorbide-sodium alginate crosslinking body, chitosan solution, glycerol and deionized water; and the cotton fiber fabric layer is a cloth woven from cotton fiber threads.

2. The method for preparing a natural multi-layered hypoallergenic clothing fabric according to claim 1, characterized in that, The preparation method of the alginate propylene glycol ester-stigmasterol microcapsules comprises the following steps: S1.1: 0.1-0.3 parts by mass of β-stigmasterol is added to 10-12 parts by mass of anhydrous ethanol, and the system is heated to 60-65°C; 1-2% of Tween 80 by mass of the system is added at a rotation speed of 200-250 r / min, and then ultrasonic treatment is performed at 300-320 W for 10-15 min to obtain a β-stigmasterol emulsion; S1.2: 2-3 parts by mass of alginate propylene glycol ester is added to 80-85 parts by mass of deionized water, and the system is heated to 50-55°C and stirred at a rotation speed of 500-550 r / min for 1-1.5 h to obtain an alginate propylene glycol ester solution; the β-stigmasterol emulsion and the alginate propylene glycol ester solution are mixed, and then 1-2% of polyvinyl alcohol by mass of the system and 0.3-0.5% of a calcium chloride solution by mass of the system are added; the system is stirred at a rotation speed of 1000-1100 r / min by a magnetic stirrer for 30-35 min, and then the product is filtered, washed with deionized water, and dried at 80-85°C for 24-25 h to obtain alginate propylene glycol ester-stigmasterol microcapsules.

3. A method of making a natural multi-layered anti-allergic apparel fabric according to claim 2, characterized in that, The preparation method of the isosorbide-sodium alginate crosslinking body comprises the following steps: S2.1: isosorbide polyurethane is dissolved in anhydrous dimethyl sulfoxide (10% w / v), and 1.2 times the molar amount of hexamethylene diisocyanate is added; the system is reacted at 60-65°C for 2-2.5 h while being protected by nitrogen to obtain an end-capped isosorbide polyurethane solution; S2.2: sodium alginate solid is dissolved in MES buffer at a solid-liquid ratio of 1g:(50-55)mL, and ultrasonic defoaming is performed for 30-35 min to obtain a sodium alginate solution; S2.3: 1-2 parts by mass of the sodium alginate solution, 0.2-0.4 parts by mass of EDC and 0.1-0.2 parts by mass of NHS are mixed and stirred at room temperature of 22-24°C for 30-35 min to activate, and the pH value is maintained at 5.5-6; then an equal volume of the end-capped isosorbide polyurethane solution is added dropwise, the system is heated to 50-55°C, and the system is stirred at a rotation speed of 200-300 r / min by a magnetic stirrer under nitrogen protection for 6-6.5 h; after the stirring is completed, 0.1M glycine is added to quench the reaction, the reaction product is dialyzed with deionized water for 72-74 h, and freeze-drying is performed to obtain an isosorbide-sodium alginate crosslinking body.

4. The method for preparing a natural multi-layered hypoallergenic clothing fabric according to claim 3, characterized in that, The preparation method of the natural multi-layer anti-allergic clothing fabric comprises the following steps: S3.1: 10-20% of propylene glycol alginate-sitosterol microcapsules, 30-35% of aqueous polyurethane and deionized water as the balance are dispersed under ultrasonic treatment at 20 kHz for 10-15 min, and the pH value is adjusted to 6-7 to obtain an anti-allergy layer coating, then the cotton fiber fabric is coated with the anti-allergy layer coating by a coating machine with one side of the cotton fiber fabric facing up, and the wet film thickness is controlled at 100-110 μm, then pre-drying at 80-85 °C for 3-4 min and drying at 150-155 °C for 2-3 min to obtain the cotton fiber fabric coated with the anti-allergy layer; S3.2: 15-18% of isosorbide-sodium alginate crosslinking body, 2-3% of chitosan solution, 3-4% of glycerol and deionized water as the balance are reacted at 50-55 °C for 2-2.5 h to obtain a waterproof layer coating, and the uncoated side of the cotton fiber fabric coated with the anti-allergy layer is coated with the waterproof layer coating by a roll coater, then immersed in a calcium chloride solution for 30-35 s after hot air drying at 60-65 °C for 10-15 min, and then dried again at 60-65 °C for 10-15 min to obtain the natural multi-layer anti-allergic clothing fabric.

5. The method for preparing a natural multi-layered hypoallergenic clothing fabric according to claim 3, characterized in that, The volume ratio of isosorbide polyurethane to anhydrous dimethyl sulfoxide is 1: (9-10).

6. The method for preparing a natural multi-layered hypoallergenic clothing fabric according to claim 4, characterized in that, The concentration of the calcium chloride solution is 0.1-0.15 M.

7. The method for preparing a natural multi-layered hypoallergenic clothing fabric according to claim 4, characterized in that, The concentration of the chitosan solution is 10-15 g / L.

8. A garment of natural multilayered anti-allergic garment fabric, characterized by, The clothing is manufactured by using the natural multi-layer anti-allergic clothing fabric prepared by the method of any one of claims 1-7. The clothing is manufactured by using the natural multi-layer anti-allergic clothing fabric prepared by the method of any one of claims 1-7.

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