Sugarcane polyphenol and mulberry leaf extract compound raw material and application thereof

Abstract

The invention discloses a sugarcane polyphenol and mulberry leaf extract compound raw material and application thereof.The sugarcane polyphenol and mulberry leaf extract compound raw material comprises sugarcane polyphenol and mulberry leaf extract, the polyphenol content of the sugarcane polyphenol is larger than or equal to 20%, the DNJ content of the mulberry leaf extract is larger than or equal to 10%, and the concentration of the polyphenol and the DNJ is 0.1-2% after the sugarcane polyphenol and the mulberry leaf extract are compounded; by compounding the sugarcane polyphenol and the mulberry leaf extract, the active and passive transfer effects of glucose in small intestines are effectively blocked, so that the rate of the glucose entering blood is controlled, the blood glucose reaction after carbohydrate food is eaten is reduced, the decomposition and absorption of the intestinal tract to carbohydrates such as starch and disaccharide are delayed, the postprandial blood sugar is stabilized, and the blood sugar content is reduced. By reasonably adjusting the concentration of polyphenols and DNJ in the compound extract to be 0.1-2%, the combination of blocking and dredging can be realized, a synergistic effect is generated, more comprehensive and more stable management of blood sugar is realized, and meanwhile, natural crops are adopted, so that the product quality safety is ensured.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of health food, in particular to a sugarcane polyphenol and mulberry leaf extract compound raw material and application thereof. BACKGROUND

[0002] Strictly controlling blood glucose levels is crucial for diabetic patients to delay the occurrence and development of complications, and is directly related to the quality of life and life expectancy of patients. Diabetes, as a global public health problem, is spreading at an alarming rate. According to the International Diabetes Federation (IDF), the number of diabetic patients worldwide continues to rise, posing a serious threat to human health and quality of life. The long-term hyperglycemic state caused by diabetes, like a hidden killer, silently erodes various organs of the human body, causing damage to the eyes, nerves, kidneys, hearts, blood vessels and other multi-organ tissues, and then causing a series of serious complications such as diabetic nephropathy, diabetic retinopathy, diabetic neuropathy, diabetic foot, etc. These complications not only bring great pain to patients, but also significantly increase medical costs and social burden. Therefore, finding a safe and effective natural hypoglycemic substitute or auxiliary treatment method is a problem that those skilled in the art need to solve. SUMMARY

[0003] In view of the defects of the prior art, the purpose of the present application is to provide a sugarcane polyphenol and mulberry leaf extract compound raw material and application thereof to solve the problems raised in the background art.

[0004] The technical problem solved by the present application adopts the following technical scheme: The present application provides a sugarcane polyphenol and mulberry leaf extract compound raw material, which comprises sugarcane polyphenol and mulberry leaf extract, the polyphenol content of the sugarcane polyphenol is ≥20%, the DNJ content of the mulberry leaf extract is ≥10%, and the concentration of polyphenols and DNJ after compounding the sugarcane polyphenol and mulberry leaf extract is 0.1-2%.

[0005] Preferably, the polyphenol content of the sugarcane polyphenol is 20-30%, and the DNJ content of the mulberry leaf extract is 10-20%.

[0006] Preferably, the concentration ratio of polyphenols and DNJ after compounding the sugarcane polyphenol and mulberry leaf extract is 1: (1-2).

[0007] Preferably, the extraction method of the mulberry leaf extract comprises the following steps: S1, crushing the pretreated mulberry leaves to obtain extraction raw materials, adding 60% ethanol solution according to the solid-liquid ratio of 1:20 (g / mL), and placing it in an ultrasonic device for 30 min; S2, then repeat extraction 3-5 times, combined filtrate, by centrifugal separation to obtain supernatant, supernatant vacuum concentration, mulberry leaf extract DNJ content ≥10%.

[0008] Preferably, the extraction of raw materials added crushed turmeric, corn silk and rehmannia, and through 40 mesh sieve, mulberry leaves, turmeric, corn silk and rehmannia mass ratio of 5:1:2:1.

[0009] Preferably, the ultrasonic equipment extraction power is 280-300W, the frequency is 35-40kHz.

[0010] Preferably, the centrifugal separation speed is 4000r / min, centrifugal separation 13-15min, the supernatant vacuum concentration temperature is 38-40℃.

[0011] Preferably, the compounding method comprises the following steps: Step one, the mulberry leaf extract and sugarcane polyphenol are accurately weighed according to different mass ratios, then put into the reaction container of the stirrer, add 8-10 parts of deionized water, so that the total volume of the solution reaches 2 / 3 of the volume of the reaction container; Step two, the reaction container is heated to 40-45℃, the stirring equipment is started, the stirring speed is 300r / min, 0.2-0.3 parts of antioxidant and 0.1-0.2 parts of thickening agent are slowly added during the heating process; Step three, the pH value is controlled between 6.8-7.8 by adding 0.12-0.15mol / L hydrochloric acid or sodium hydroxide solution dropwise, stirring for 1-1.5h, after the reaction is completed, the mulberry leaf extract and sugarcane extract compounding raw materials are obtained.

[0012] Preferably, the antioxidant is vitamin C, which prevents the oxidation of active ingredients in the compounding raw materials, and the thickening agent is pectin.

[0013] The prepared sugarcane polyphenol and mulberry leaf extract compound raw material and application thereof, by adopting the compounding of sugarcane polyphenol and mulberry leaf extract, the sugarcane polyphenol is rich in polyphenols, which has strong antioxidant and anti-inflammatory effects, can inhibit the activity of alpha-glucosidase and alpha-amylase in the small intestine, enhance insulin sensitivity, protect pancreatic beta cells, and has anti-inflammatory and antioxidant effects, effectively blocks the active and passive transport of glucose in the small intestine, thereby controlling the rate of glucose entering the blood, reducing the blood glucose response after eating carbohydrate food, and the mulberry leaf extract contains various bioactive components, among which 1-deoxynojirimycin (DNJ) is a potent alpha-glucosidase inhibitor, which can tightly bind to the sugar-cleaving enzyme in the body, reduce the binding site of the sugar-cleaving enzyme and sugar, thereby delaying the decomposition and absorption of carbohydrates such as starch and disaccharides in the intestinal tract, stabilizing postprandial blood glucose, by combining the use of sugarcane polyphenol and mulberry leaf extract, and reasonably adjusting the concentration of polyphenols and DNJ in the compound extract to 0.1-2%, the combination of blocking and dredging can achieve synergistic effect, achieve more comprehensive and stable management of blood glucose, and at the same time, the use of natural crops ensures the quality and safety of the product.

[0014] Compared with the prior art, the present application has the following advantages: The present application adds turmeric, corn silk and rehmannia root in the mulberry leaf extract, the curcumin in turmeric has anti-inflammatory, antioxidant, hypoglycemic and immunoregulatory effects, improves the glucose and lipid metabolism disorders of diabetic organism, and the active components of catalpol and rehmannia glycoside in rehmannia root not only have a certain hypoglycemic effect, but also can improve the symptoms of kidney yin deficiency in diabetic patients by tonifying liver and kidney yin, improve the immunity and antioxidant capacity of the body, and the flavonoids and polysaccharides in corn silk also have a certain effect of inhibiting the activity of alpha-glucosidase, which synergizes with DNJ in mulberry leaf to further enhance the inhibitory effect on carbohydrate digestion and absorption, thereby achieving the purpose of slow-release of carbohydrates through the synergistic effect of turmeric, corn silk and rehmannia root, and avoiding the rapid rise of postprandial blood glucose. DETAILED DESCRIPTION

[0015] The technical solutions in the embodiments of the present application will be described clearly and completely in combination with specific embodiments. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0016] The application of the embodiment provides a sugarcane polyphenol and mulberry leaf extract compound raw material, which is applied to control blood sugar, and includes sugarcane polyphenol and mulberry leaf extract, the polyphenol content of the sugarcane polyphenol is greater than or equal to 20%, the DNJ content of the mulberry leaf extract is greater than or equal to 10%, and the concentration of the polyphenol and the DNJ after the sugarcane polyphenol and the mulberry leaf extract are compounded is 0.1-2%.

[0017] The polyphenol content of the sugarcane polyphenol of the embodiment is 20-30%, and the DNJ content of the mulberry leaf extract is 10-20%.

[0018] The concentration ratio of the polyphenol and the DNJ after the sugarcane polyphenol and the mulberry leaf extract of the embodiment are compounded is 1: (1-2).

[0019] The extraction method of the mulberry leaf extract of the embodiment includes the following steps: S1, crushing the pretreated mulberry leaves to obtain an extraction raw material, adding 60% ethanol solution according to the solid-liquid ratio of 1:20 (g / mL), and placing it in an ultrasonic device for 30 min; S2, then repeating the extraction for 3-5 times, combining the filtrate, and obtaining supernatant by centrifugal separation, and reducing pressure concentration of the supernatant, so that the DNJ content of the mulberry leaf extract is greater than or equal to 10%.

[0020] The extraction raw material of the embodiment adds crushed turmeric, corn silk and rehmannia root, and is sieved through a 40-mesh sieve, and the mass ratio of the mulberry leaf, turmeric, corn silk and rehmannia root is 5:1:2:1.

[0021] The power of the ultrasonic device extraction of the embodiment is 280-300 W, and the frequency is 35-40 kHz.

[0022] The rotation speed of the centrifugal separation of the embodiment is 4000 r / min, the centrifugal separation time is 13-15 min, the temperature of the supernatant reduction pressure concentration is 38-40℃, and low-temperature concentration is used, and the original phenolic composition can be maintained after compounding.

[0023] The compounding method of the embodiment includes the following steps: Step one, accurately weighing the sugarcane polyphenol and the mulberry leaf extract according to different mass ratios, then placing them in the reaction container of the stirrer, adding 8-10 parts of deionized water, and making the total volume of the solution reach 2 / 3 of the volume of the reaction container; Step two, heating the reaction container to 40-45℃, starting the stirring device, and the stirring speed is 300 r / min, slowly adding 0.2-0.3 parts of antioxidant and 0.1-0.2 parts of thickening agent during the heating process, promoting the mutual action between molecules, and forming a stable compound; Step three, in the reaction process, the pH of the solution is monitored by pH meter, the pH value is controlled between 6.8-7.8 by adding 0.12-0.15 mol / L hydrochloric acid or sodium hydroxide solution, stirring for 1-1.5 h to maintain the stability of the reaction environment, ensure the smooth progress of the compounding reaction, after the reaction, the raw material of sugarcane extract and mulberry leaf extract is obtained.

[0024] The antioxidant of the embodiment is vitamin C, which prevents the active ingredients in the raw material from being oxidized, and the thickening agent is pectin, which is a natural plant gum, low in calories and enhances the stability of the product.

[0025] The embodiment. Example 1.

[0026] The embodiment provides a raw material of sugarcane polyphenol and mulberry leaf extract, which comprises sugarcane polyphenol and mulberry leaf extract, the polyphenol content of the sugarcane polyphenol is 20%, the DNJ content of the mulberry leaf extract is 10%, and the concentration of polyphenols and DNJ after compounding of the sugarcane polyphenol and the mulberry leaf extract is 0.1%.

[0027] The concentration ratio of polyphenols and DNJ after compounding of the sugarcane polyphenol and the mulberry leaf extract of the embodiment is 1:1.

[0028] The extraction method of the mulberry leaf extract of the embodiment comprises the following steps: S1, the pretreated mulberry leaf is crushed to obtain an extraction raw material, 60% ethanol solution is added according to the solid-liquid ratio of 1:20 (g / mL), and the extraction is carried out in an ultrasonic device for 30 min; S2, then repeat the extraction for 3-5 times, combine the filtrate, and obtain the supernatant by centrifugal separation, and the DNJ content of the mulberry leaf extract is ≥10% after the supernatant is concentrated under reduced pressure.

[0029] The extraction raw material of the embodiment is added with crushed turmeric, corn silk and rehmannia glutinosa, and is sieved through a 40-mesh sieve, and the mass ratio of mulberry leaf, turmeric, corn silk and rehmannia glutinosa is 5:1:2:1.

[0030] The power of the ultrasonic device extraction of the embodiment is 280 W, and the frequency is 35 kHz.

[0031] The rotation speed of the centrifugal separation of the embodiment is 4000 r / min, the centrifugal separation time is 13 min, the temperature of the supernatant concentrated under reduced pressure is 38℃, and low-temperature concentration is used, and the original phenolic composition can be maintained after compounding.

[0032] The compounding method of the embodiment comprises the following steps: Step one, the sugarcane polyphenol and mulberry leaf extract according to the different mass ratio of accurate weighing, then put into the reaction container of stirrer, add 8 parts of deionized water, make the total volume of solution to 2 / 3 of the volume of reaction container; Step two, the reaction container is heated to 40℃, open the stirring equipment, the stirring speed is 300r / min, slowly add 0.2 parts of antioxidant and 0.1 parts of thickening agent during the heating process, promote the interaction between molecules, form stable compound; Step three, in the reaction process, the pH value of the solution is monitored by pH meter, the pH value is controlled between 6.8 by adding 0.12mol / L hydrochloric acid or sodium hydroxide solution, the reaction is stirred for 1h to maintain the stability of the reaction environment and ensure the smooth progress of the reaction, after the reaction, the sugarcane extract and mulberry leaf extract compound raw material is obtained.

[0033] The antioxidant of the embodiment is vitamin C, which prevents the oxidation of active ingredients in the compound raw material, and the thickening agent is pectin, which is a natural plant gum with low heat and enhances the stability of the product. Example 2.

[0034] The embodiment provides a sugarcane polyphenol and mulberry leaf extract compound raw material, which comprises sugarcane polyphenol and mulberry leaf extract, the polyphenol content of the sugarcane polyphenol is 25%, the DNJ content of the mulberry leaf extract is 15%, and the concentration of polyphenols and DNJ after the compound of the sugarcane polyphenol and the mulberry leaf extract is 2%.

[0035] The concentration ratio of polyphenols and DNJ after the compound of the sugarcane polyphenol and the mulberry leaf extract of the embodiment is 1:2.

[0036] The extraction method of the mulberry leaf extract of the embodiment comprises the following steps: S1, the pretreated mulberry leaf is crushed to obtain an extraction raw material, 60% ethanol solution is added according to the solid-liquid ratio of 1:20 (g / mL), and the extraction is carried out in an ultrasonic device for 30min; S2, then repeat the extraction for 4 times, combine the filtrate, and obtain the supernatant by centrifugal separation, and the DNJ content of the mulberry leaf extract is ≥10% by reducing pressure concentration.

[0037] The extraction raw material of the embodiment is added with crushed turmeric, corn silk and rehmannia glutinosa, and is sieved through a 40 mesh sieve, and the mass ratio of mulberry leaf, turmeric, corn silk and rehmannia glutinosa is 5:1:2:1.

[0038] The power of the ultrasonic device of the embodiment is 290W, and the frequency is 38kHz.

[0039] The centrifugal separation speed of this embodiment is 4000 r / min, the centrifugal separation time is 14 min, the temperature of the supernatant is 39℃, and low-temperature concentration is used. After compounding, the original phenolic composition can be maintained.

[0040] The compounding method of this embodiment includes the following steps: Step 1: Accurately weigh the sugarcane polyphenols and mulberry leaf extract according to different mass ratios, then put them into the reaction container of the stirrer, add 9 parts of deionized water, and make the total volume of the solution reach 2 / 3 of the volume of the reaction container. Step 2: Heat the reaction container to 43℃, start the stirring device, and set the stirring speed to 300 r / min. Slowly add 0.3 parts of antioxidant and 0.2 parts of thickening agent during the heating process to promote intermolecular interaction and form a stable compound. Step 3: During the reaction, monitor the pH value of the solution with a pH meter. Add 0.14 mol / L hydrochloric acid or sodium hydroxide solution to control the pH value between 7. Stir for 1-1.5 h to maintain the stability of the reaction environment and ensure the smooth progress of the compounding reaction. After the reaction is completed, the sugarcane extract and mulberry leaf extract compound raw material is obtained.

[0041] The antioxidant of this embodiment is vitamin C, which prevents the oxidation of active ingredients in the compound raw material. The thickening agent is pectin, which is a natural plant gum with low calories and enhances product stability. Example 3.

[0042] This embodiment provides a sugarcane polyphenol and mulberry leaf extract compound raw material, which includes sugarcane polyphenol and mulberry leaf extract. The polyphenol content of sugarcane polyphenol is 30%, the DNJ content of mulberry leaf extract is 20%, and the concentration of polyphenols and DNJ after compounding of sugarcane polyphenol and mulberry leaf extract is 2%.

[0043] The concentration ratio of polyphenols and DNJ after compounding of sugarcane polyphenol and mulberry leaf extract in this embodiment is 1:2.

[0044] The extraction method of mulberry leaf extract in this embodiment includes the following steps: S1: Crush the pretreated mulberry leaves to obtain the extraction raw material. Add 60% ethanol solution according to the solid-liquid ratio of 1:20 (g / mL) and put it into the ultrasonic device for 30 min. S2: Then repeat the extraction for 5 times, combine the filtrate, and obtain the supernatant by centrifugal separation. Concentrate the supernatant under reduced pressure to make the DNJ content of the mulberry leaf extract ≥10%.

[0045] In this embodiment, crushed turmeric, corn silk, and rehmannia are added to the extraction raw material and sieved through a 40-mesh sieve. The mass ratio of mulberry leaf, turmeric, corn silk, and rehmannia is 5:1:2:1.

[0046] The power extracted by the ultrasonic device of the embodiment is 300W, and the frequency is 40kHz.

[0047] The rotation speed of the centrifugal separation of the embodiment is 4000r / min, the centrifugal separation is performed for 15min, the temperature of the concentration of the supernatant under reduced pressure is 40℃, the low-temperature concentration is used, and the original phenolic composition can be maintained after compounding.

[0048] The compounding method of the embodiment includes the following steps: Step one, accurately weigh the sugarcane polyphenol and mulberry leaf extract according to different mass ratios, then put them into the reaction container of the stirrer, add 10 parts of deionized water, and make the total volume of the solution reach 2 / 3 of the volume of the reaction container; Step two, heat the reaction container to 45℃, start the stirring equipment, and the stirring speed is 300r / min. Slowly add 0.3 parts of antioxidant and 0.2 parts of thickening agent during the heating process, promote the interaction between molecules, and form a stable compound. Step three, monitor the pH value of the solution by using a pH meter during the reaction process. The pH value is controlled between 7.8 by adding 0.15mol / L hydrochloric acid or sodium hydroxide solution. Stir for 1.5h to maintain the stability of the reaction environment and ensure the smooth progress of the compounding reaction. After the reaction is completed, the sugarcane extract and mulberry leaf extract compounding raw materials are obtained.

[0049] The antioxidant of the embodiment is vitamin C, which prevents the oxidation of active ingredients in the compounding raw materials. The thickening agent is pectin, which is a natural plant gum with low heat and enhances the stability of the product.

[0050] Comparative Example 1. Unlike Example 3, the blood glucose control raw materials are prepared using a common formula. Take 20 mice with diabetes, 5 mice in each group, a total of 4 groups, and the average blood glucose of each group of mice is basically consistent. Each group corresponds to Examples 1-3 and Comparative Example 1 and is numbered A / B / C / D. They are raised in a normal environment and fed with the compounding raw materials every day. The average blood glucose is measured every 10 days. The mice in groups A / B / C / D are detected for 3 consecutive weeks. The test results are as follows:

[0051] As can be seen from examples 1-3, comparative example 1, the use of the prepared sugarcane polyphenol and mulberry leaf extract compound raw material and its application, by combining the use of sugarcane polyphenol and mulberry leaf extract, and reasonably adjusting the concentration of polyphenols and DNJ in the compound extract to 0.1-2%, the combination of blocking and dredging can achieve synergistic effect, achieve more comprehensive and more stable management of blood sugar, and the reduction of blood sugar is obviously higher than that of other sugar control raw materials.

[0052] The innovation of the present application is that: The present application is prepared by compounding sugarcane polyphenol and mulberry leaf extract, and the sugarcane polyphenol is rich in polyphenols, which have strong antioxidant and anti-inflammatory effects, can inhibit the activity of alpha-glucosidase and alpha-amylase in the small intestine, enhance insulin sensitivity, protect pancreatic beta cells, and have anti-inflammatory and antioxidant effects, effectively block the active and passive transport of glucose in the small intestine, thereby controlling the rate of glucose entering the blood, reducing the blood sugar response after eating carbohydrate food, and the mulberry leaf extract contains a variety of bioactive components, among which 1-deoxynojirimycin (DNJ) is a potent alpha-glucosidase inhibitor that can tightly bind to the body's sugar-decomposing enzymes, reducing the binding sites of sugar-decomposing enzymes and sugar, thereby delaying the decomposition and absorption of carbohydrates such as starch and disaccharides in the intestinal tract, and stabilizing postprandial blood sugar.

[0053] It is apparent to those skilled in the art that the present application is not limited to the details of the above exemplary embodiments, but can be implemented in other concrete forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all respects as illustrative and not restrictive, and the scope of the present application is defined by the appended claims rather than the above description, and it is intended to encompass all changes falling within the meaning and scope of the equivalent elements of the claims.

[0054] In addition, it should be understood that although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can be combined appropriately to form other embodiments that those skilled in the art can understand.

Claims

1. A compound raw material of sugarcane polyphenol and mulberry leaf extract, characterized in that, The application relates to a compound of sugarcane polyphenol and mulberry leaf extract, wherein the polyphenol content of the sugarcane polyphenol is greater than or equal to 20%, the DNJ content of the mulberry leaf extract is greater than or equal to 10%, and the concentration of polyphenols and DNJ after compounding of the sugarcane polyphenol and the mulberry leaf extract is 0.1-2%.

2. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 1, characterized in that, The polyphenol content of the sugarcane polyphenol is 20-30%, and the DNJ content of the mulberry leaf extract is 10-20%.

3. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 2, characterized in that, The concentration ratio of polyphenols and DNJ after compounding of the sugarcane polyphenol and the mulberry leaf extract is 1: (1-2).

4. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 3, characterized in that, The extraction method of the mulberry leaf extract comprises the following steps: S1, crushing pretreated mulberry leaves to obtain extraction raw materials, adding 60% ethanol solution according to a material-liquid ratio of 1:20 (g / mL), and placing the mixture into an ultrasonic device for extraction for 30 min; S2, then repeating the extraction for 3-5 times, combining the filtrates, obtaining supernatant through centrifugal separation, and reducing the pressure to concentrate the supernatant so that the DNJ content of the mulberry leaf extract is greater than or equal to 10%.

5. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 4, characterized in that, The extraction raw materials are added with crushed turmeric, corn silk and rehmannia root, and are sieved through a 40-mesh screen; the mass ratio of the mulberry leaves, the turmeric, the corn silk and the rehmannia root is 5:1:2:

1.

6. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 4, characterized in that, The power of the ultrasonic device for extraction is 280-300 W, and the frequency is 35-40 kHz.

7. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 4, characterized in that, The rotating speed of the centrifugal separation is 4000 r / min, the centrifugal separation is performed for 13-15 min, and the temperature for reducing the pressure to concentrate the supernatant is 38-40 DEG C.

8. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 1, characterized in that, The compounding method comprises the following steps: Step one, accurately weighing the sugarcane polyphenol and the mulberry leaf extract according to different mass ratios, then placing the mixture into a reaction container of a stirrer, adding 8-10 parts of deionized water so that the total volume of the solution reaches 2 / 3 of the volume of the reaction container; Step two, heating the reaction container to 40-45 DEG C, starting the stirring device, and setting the stirring speed to 300 r / min; slowly adding 0.2-0.3 parts of an antioxidant and 0.1-0.2 parts of a thickening agent during the temperature rising process; Step three, controlling the pH value in the range of 6.8-7.8 by adding 0.12-0.15 mol / L hydrochloric acid or sodium hydroxide solution dropwise, stirring for 1-1.5 h, and obtaining the compound of the sugarcane extract and the mulberry leaf extract after the reaction is completed.

9. The compound raw material of sugarcane polyphenol and mulberry leaf extract according to claim 8, characterized in that, The antioxidant is vitamin C, and the thickening agent is pectin.

10. The compound of the sugarcane polyphenol and the mulberry leaf extract according to any one of claims 1-9 in the application of controlling blood sugar.

Images