An apparatus cleaning device for pharmaceutical research and development

Abstract

The application relates to the technical field of medical research and development, and particularly discloses a device for cleaning instruments used in medical research and development, which comprises an ultrasonic cleaning machine, the front and rear top ends and the left and right sides of the ultrasonic cleaning machine are provided with moving grooves in the up-down direction, a water inlet pipe is arranged at the left top end of the ultrasonic cleaning machine, a drain pipe is arranged at the right bottom end of the ultrasonic cleaning machine, the upper and lower ends of a guide rod are arranged on the inner cavities of the moving grooves, a spring sleeve is arranged on the outer wall of the guide rod, and the bottom end of the spring is clamped to the bottom end of the inner cavity of the moving groove. The device realizes automatic recording of the number of times of cleaning agent use and intelligent monitoring of the turbidity of the cleaning agent, ensures that the cleaning agent is always in a high-efficiency cleaning state, avoids the influence of the decline of the cleaning ability caused by the aging or improper replacement of the cleaning agent on the cleanliness in the process of drug research and development, significantly improves the cleaning efficiency and quality of the instruments, and guarantees the safety of the staff and the accuracy in the process of drug research and development.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical research and development technology, specifically to a device cleaning apparatus for pharmaceutical research and development. Background Technology

[0002] In pharmaceutical research and development, the cleanliness of laboratory equipment directly affects the accuracy of experimental data, the purity of drug components, and the safety of research and development. If the equipment contains residual drug solutions, impurities, or microorganisms from previous experiments, it may lead to deviations in experimental results, or even cause cross-contamination, delaying the research and development cycle or creating safety hazards. Therefore, equipment cleaning is a critical and fundamental step in pharmaceutical research and development.

[0003] The core flaw of existing technology:

[0004] 1. Inability to automatically record the number of times cleaning agents are used: Most current cleaning devices rely on manual recording of the frequency and cycle of cleaning agent use, which is prone to omissions and errors. Cleaning agents gradually become ineffective after repeated use, and the subjective nature of manually judging when to replace them often leads to a decline in cleaning ability due to untimely replacement, or waste of resources due to overly frequent replacement.

[0005] 2. Lack of methods for monitoring the turbidity of cleaning agents: The turbidity of cleaning agents is an important indicator of their cleaning ability, but existing equipment lacks real-time monitoring capabilities. Workers must visually inspect the cleaning agents to determine if they have become ineffective, which is not only inaccurate but may also lead to overlooking potential contamination risks due to visual errors, resulting in incomplete cleaning of equipment.

[0006] 3. Cleaning agent mixing relies on manual operation: In pharmaceutical research and development, different types of instruments (such as high-temperature resistant instruments and precision glass instruments) require specific ratios of cleaning agents (such as acidic cleaning agents and neutral descaling agents). Existing equipment requires manual weighing and mixing of cleaning agents, which is cumbersome and prone to mixing errors, affecting the cleaning effect and increasing labor costs and operational risks.

[0007] The aforementioned defects directly lead to multiple problems: First, the cleaning ability is unstable, affecting the cleanliness of instruments and thus interfering with the accuracy of drug development data; second, there are many manual operation steps, increasing the labor intensity of staff and posing safety hazards due to improper operation (such as contact of cleaning agents with the skin, misjudging the timing of replacement); third, the cleaning efficiency is low, which cannot meet the high-frequency and high-precision instrument cleaning needs in pharmaceutical research and development, indirectly restricting the research and development progress. Summary of the Invention

[0008] The purpose of this invention is to provide a device cleaning apparatus for pharmaceutical research and development, so as to at least solve the problems of existing technologies that cannot automatically record the number of uses, cannot automatically monitor the turbidity of the cleaning agent, and cannot automatically mix the cleaning agent.

[0009] To achieve the above objectives, the present invention provides the following technical solution: a medical device cleaning apparatus for pharmaceutical research and development, comprising: an ultrasonic cleaner, a movable tank, a water inlet pipe, a drain pipe, a guide rod, a spring, a support rod, a first pressing rod, a reset mechanism, a dispensing mechanism, a basket, a ball valve, a valve stem, and a first gear. The ultrasonic cleaner has movable tanks on its front and rear top sides and left and right sides along the vertical direction. The water inlet pipe is located at the left top side of the ultrasonic cleaner. The drain pipe is located at the right bottom side of the ultrasonic cleaner. The upper and lower ends of the guide rod are respectively located on the upper and lower sides of the inner cavity of the movable tank. The spring is sleeved on the outer wall of the guide rod, and the bottom end of the spring is engaged with the bottom end of the inner cavity of the movable tank. The four corners of the outer wall of the support rod are slidably fitted into the top of the inner cavity of the four movable slots. The outer wall of the support rod is slidably sleeved on the top of the outer wall of the guide rod. The top of the spring is snapped into the outer wall of the support rod. The top of the first pressing rod is located at the middle of the front side of the outer wall of the support rod. The reset mechanism is located at the bottom right side of the ultrasonic cleaner. The dispensing mechanism is located at the rear side of the ultrasonic cleaner. The left and right sides of the outer wall of the basket overlap the left and right sides of the outer wall of the support rod, and the basket is embedded in the inner cavity of the ultrasonic cleaner. The ball valve is located on the outer wall of the drain pipe. The valve stem is located on the right side of the ball valve. The first gear is sleeved on the outer wall of the valve stem and locked by a set screw.

[0010] Preferably, the instrument cleaning device for pharmaceutical research and development further includes four hooks, which are respectively located at the bottom front and rear sides and left and right ends of the basket, and the outer wall of the support rod is adapted to be inserted into the inner cavity of the hook.

[0011] Preferably, the instrument cleaning device for pharmaceutical research and development further includes a hook-type electronic counter counting button, a protective shell, an electronic counter, and an electronic counter reset button; the electronic counter counting button is located in the middle of the front side of the ultrasonic cleaner, and its position corresponds to the position of the first pressing rod, with the electronic counter counting button located below the first pressing rod; the protective shell is located in the middle of the front side of the ultrasonic cleaner, the electronic counter counting button is located in the inner cavity of the protective shell, and the bottom end of the first pressing rod slidably extends into the inner cavity of the protective shell; the electronic counter is located on the front side of the protective shell, and the electronic counter and the electronic counter counting button are electrically connected; the electronic counter reset button is located at the bottom right side of the ultrasonic cleaner, and the electronic counter reset button and the electronic counter are electrically connected;

[0012] Preferably, for pressing the electronic counter reset button, the reset mechanism includes: a bracket, a drive cavity, a second pressing rod, a sleeve, a sliding column, a rotating rod, a drive column, a drive groove, and a second gear; the bracket is located at the bottom right side of the ultrasonic cleaner, the electronic counter reset button is located in the inner cavity of the bracket, and the drive cavity is opened on the right side of the bracket; the second pressing rod is located on the left side of the inner cavity of the drive cavity, and the second pressing rod slidably extends into the inner cavity of the bracket, the position of the second pressing rod corresponding to the position of the electronic counter reset button. The outer wall of the second pressing rod is racetrack-shaped; the sleeve is located at the right end of the second pressing rod; there are two sliding pillars, which are respectively located at the front and rear ends of the right side of the inner wall of the sleeve; the rotating rod is located at the middle of the right side of the bracket, and the left end of the rotating rod extends rotatably into the inner cavity of the driving chamber; the driving column is located at the left end of the rotating rod, and the driving column is slidably and rotatably inserted into the inner cavity of the sleeve. The outer wall of the driving column has driving grooves on both the front and rear sides, and the sliding pillar is slidably and appropriately inserted into the right side of the inner cavity of the driving groove.

[0013] Preferably, in order to control the opening and closing of the ball valve, a second gear is sleeved on the outer wall of the rotating rod and locked by a set screw, wherein the second gear meshes with the first gear.

[0014] Preferably, to automatically add cleaning agent to the ultrasonic cleaner in a certain proportion, the dispensing mechanism includes: a liquid tank, a liquid level window, a liquid inlet, a mounting bracket, a jacket, a piston cylinder, a piston, a piston rod, an electric telescopic rod, a first one-way valve, a delivery pipe, and a second one-way valve. The liquid tanks are multiple in number, equidistantly arranged at the rear bottom of the ultrasonic cleaner along the left-right direction. A liquid level window is provided on the rear side of each liquid tank along the up-down direction, and a liquid inlet is provided on the rear top of each liquid tank. The mounting brackets are also multiple in number, equidistantly arranged at the top rear of the ultrasonic cleaner along the left-right direction. One liquid tank corresponds to another; the jacket is located at the bottom front end of the mounting frame; the piston cylinder is detachably and compatiblely inserted into the inner cavity of the jacket; the piston is slidably and compatiblely inserted into the bottom end of the inner cavity of the piston cylinder; the piston rod is located at the top end of the piston, and the top end of the piston rod slidably extends out of the top end of the piston cylinder; an electric telescopic rod is located at the top end of the mounting frame, and the bottom end of the electric telescopic rod is located at the top end of the piston rod; the first one-way valve is located at the bottom end of the outer wall of the piston cylinder; the top end of the infusion tube is located at the bottom end of the inner cavity of the piston cylinder, and the bottom end of the infusion tube extends into the bottom end of the inner cavity of the liquid tank; the second one-way valve is located in the middle of the outer wall of the infusion tube.

[0015] Preferably, in order to monitor the turbidity of the cleaning agent in the ultrasonic cleaner, the inner cavity of the ultrasonic cleaner is further provided with a turbidity sensor and a display. The turbidity sensor is located at the bottom rear side of the inner cavity of the ultrasonic cleaner; the display is located at the middle front side of the ultrasonic cleaner, and the display and the turbidity sensor are electrically connected.

[0016] Preferably, after the basket containing the instrument is placed into the ultrasonic cleaner, the weight of the basket causes the support rod to move down and compress the spring. The support rod then drives the first pressing rod to press the electronic counter's counting button, causing the electronic counter to increment by one, thus recording the number of uses.

[0017] Preferably, when the turbidity of the cleaning agent is high or the electronic counter count reaches the threshold, the rotating rod is rotated to drive the second gear and the drive column to rotate. The second gear meshes with the first gear to make the ball valve counter count return to zero.

[0018] The instrument cleaning device for pharmaceutical research and development proposed in this invention has the following advantages:

[0019] 1. This invention uses a mesh basket to store instruments to be cleaned, and a support rod to support the mesh basket containing the instruments. Under the gravity of the mesh basket, the support rod can be pressed to move the first pressing rod downward. The first pressing rod presses the counting button of the electronic counter, causing the count on the electronic counter to increment by one. Thus, the electronic counter can record the number of times the cleaning agent is used in the ultrasonic cleaner.

[0020] 2. This invention allows for the storage of different cleaning agents in a liquid tank. Clean water is supplied to the inner cavity of the ultrasonic cleaner via a water inlet pipe. The cleaning agent is prepared according to the type of instrument being cleaned. The electric telescopic rod corresponding to the required cleaning agent is activated. This electric telescopic rod, through a piston rod, moves the piston upwards, drawing the cleaning agent from the liquid tank into the piston cylinder's inner cavity under pressure. This continues until the electric telescopic rod moves the piston to a suitable height. Then, the electric telescopic rod again moves the piston downwards, pushing the cleaning agent from the piston cylinder's inner cavity into the ultrasonic cleaner's inner cavity through the bottom of the piston cylinder. The cleaning agent mixes with the water in the ultrasonic cleaner, completing the cleaning agent preparation. The ultrasonic cleaner is then used to clean the instruments in the basket's inner cavity.

[0021] 3. This invention utilizes a turbidity sensor to detect the turbidity of the cleaning agent and displays the turbidity value on a display. When the cleaning agent in the ultrasonic cleaner needs to be replaced, rotating the rotating rod drives the drive column and the second gear to rotate. The rotation of the second gear, in conjunction with the first gear, causes the valve rod to rotate, thereby controlling the opening and closing of the ball valve. The rotation of the drive column, through the cooperation between the drive groove and the sliding column, causes the sleeve to move the second pressing rod to the left until the second pressing rod presses the electronic counter reset button, thus clearing the value recorded on the electronic counter and starting a new calculation cycle. At this time, the ball valve is fully open, allowing the cleaning agent in the ultrasonic cleaner to be discharged from the inner cavity of the ultrasonic cleaner through the drain pipe.

[0022] 4. This device automatically records the number of times the cleaning agent is used and intelligently monitors the turbidity of the cleaning agent, ensuring that the cleaning agent is always in a highly efficient cleaning state. This avoids the decline in cleaning ability caused by the aging or improper replacement of the cleaning agent, which would affect the cleanliness during the drug development process. It significantly improves the cleaning efficiency and quality of instruments, and ensures the safety of staff and the accuracy of the drug development process. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of the present invention;

[0024] Figure 2 This is the front view of the present invention;

[0025] Figure 3 This is an exploded view of the present invention;

[0026] Figure 4 This is a schematic diagram of the batching mechanism;

[0027] Figure 5 This is a schematic diagram of the reset mechanism;

[0028] Figure 6 An exploded view of the batching mechanism;

[0029] Figure 7 This is an exploded view of the reset mechanism;

[0030] Figure 8 for Figure 2 Enlarged view of point A;

[0031] Figure 9 for Figure 3 Enlarged view of point B;

[0032] Figure 10 for Figure 3 Enlarged view of point C;

[0033] Figure 11 for Figure 3 Enlarged view of point D;

[0034] Figure 12 for Figure 7 Enlarged view of point E.

[0035] In the diagram: 1. Ultrasonic cleaner; 2. Moving tank; 3. Water inlet pipe; 4. Drain pipe; 5. Guide rod; 6. Spring; 7. Reset mechanism; 71. Bracket; 72. Drive chamber; 73. Second pressing rod; 74. Sleeve; 75. Sliding column; 76. Rotating rod; 77. Drive column; 78. Drive tank; 79. Second gear; 8. Dispensing mechanism; 81. Liquid tank; 82. Liquid level window; 83. Liquid inlet; 84. Mounting bracket; 85. Jacket; 86. Piston 87. Cylinder; 88. Piston; 89. Piston rod; 80. Electric telescopic rod; 810. First check valve; 811. Infusion tube; 812. Second check valve; 9. Support rod; 10. Net basket; 11. Hook; 12. First pressing rod; 13. Electronic counter counting button; 14. Protective shell; 15. Electronic counter; 16. Electronic counter reset button; 17. Ball valve; 18. Valve stem; 19. First gear; 20. Turbidity sensor; 21. Display. Detailed Implementation

[0036] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0037] Please see Figures 1-12This invention provides a technical solution for a medical device cleaning device for pharmaceutical research and development, comprising: an ultrasonic cleaner 1, a movable tank 2, a water inlet pipe 3, a drain pipe 4, a guide rod 5, a spring 6, a reset mechanism 7, a dispensing mechanism 8, a support rod 9, a basket 10, a hook 11, a first pressing rod 12, an electronic counter counting button 13, a protective shell 14, an electronic counter 15, an electronic counter reset button 16, a ball valve 17, a valve stem 18, a first gear 19, a turbidity sensor 20, and a display 21. The ultrasonic cleaner 1 has movable tanks 2 on both the front and rear sides, top, left and right sides, along the vertical direction. The ultrasonic cleaner 1 is existing technology and will not be described in detail here. The ultrasonic cleaner 1 is used to clean medical devices. The water inlet pipe 3... Located at the top left side of the ultrasonic cleaner 1, the water inlet pipe 3 delivers clean water into the inner cavity of the ultrasonic cleaner 1. The drain pipe 4 is located at the bottom right side of the ultrasonic cleaner 1, allowing the cleaning agent in the inner cavity of the ultrasonic cleaner 1 to be discharged. The upper and lower ends of the guide rod 5 are respectively located on the upper and lower sides of the inner cavity of the moving groove 2. The guide rod 5 is used to limit the position of the support rod 9. The spring 6 is sleeved on the outer wall of the guide rod 5, and the bottom end of the spring 6 is engaged with the bottom end of the inner cavity of the moving groove 2. The spring 6 is a rotary spring, which undergoes elastic deformation after being compressed or stretched by external force and returns to its initial state after the external force is removed. The spring 6 here also supports the support rod 9. The four corners of the outer wall of the support rod 9 are slidably fitted and inserted into the support rod. The top of the inner cavity of the four movable slots 2, the outer wall of the support rod 9 is slidably sleeved on the top of the outer wall of the guide rod 5, the top of the spring 6 is snapped into the outer wall of the support rod 9, the support rod 9 is used to support the basket 10, the top of the first pressing rod 12 is set at the middle of the front side of the outer wall of the support rod 9, the first pressing rod 12 is used to press the electronic counter counting button 13, the reset mechanism 7 is set at the bottom right side of the ultrasonic cleaner 1, the reset mechanism 7 is used to cause the reading on the electronic counter 15 to return to zero and open the ball valve 17 at the same time, the dispensing mechanism 8 is set at the rear side of the ultrasonic cleaner 1, the dispensing mechanism 8 can automatically add cleaning agent to the inner cavity of the ultrasonic cleaner 1 according to a certain ratio, the left and right sides of the outer wall of the basket 10 respectively overlap the left and right sides of the outer wall of the support rod 9. The basket 10 is embedded in the inner cavity of the ultrasonic cleaner 1. The basket 10 is used to store instruments. Four hooks 11 are provided, located at the bottom, front, rear, left, and right ends of the basket 10. The outer wall of the support rod 9 is fitted into the inner cavity of the hooks 11. The hooks 11 increase the stability of the basket 10. An electronic counter button 13 is located in the center of the front side of the ultrasonic cleaner 1. The position of the electronic counter button 13 corresponds to the position of the first pressing rod 12, and the electronic counter button 13 is located below the first pressing rod 12. The electronic counter button 13 is existing technology and will not be described in detail here. Pressing the electronic counter button 13 increments the count on the electronic counter 15 by one.The distance between the top of the electronic counter counting button 13 and the bottom of the first pressing rod 12 is less than the distance between the bottom of the inner cavity of the moving groove 2 and the outer wall of the support rod 9, ensuring that the first pressing rod 12 can press the electronic counter counting button 13. The protective shell 14 is located in the middle of the front side of the ultrasonic cleaner 1. The electronic counter counting button 13 is located in the inner cavity of the protective shell 14. The bottom of the first pressing rod 12 can slide into the inner cavity of the protective shell 14. The protective shell 14 is used to protect the electronic counter counting button 13 and prevent accidental activation. The electronic counter 15 is located on the front side of the protective shell 14. The electronic counter 15 and the electronic counter counting button 13 are electrically connected. The electronic counter 15 is an existing counter, which will not be described in detail here. The electronic counter 15 is used to record the number of times the cleaning agent is used in the ultrasonic cleaner 1. The electronic counter reset button 16 is located at the bottom right side of the ultrasonic cleaner 1. The counter reset button 16 and the electronic counter 15 are electrically connected. The electronic counter reset button 16 is existing technology and will not be described in detail here. The electronic counter reset button 16 is used to reset the count on the electronic counter 15 to zero. The ball valve 17 is located on the outer wall of the drain pipe 4. The ball valve 17 is used to control the opening and closing of the drain pipe 4. The valve stem 18 is located on the right side of the ball valve 17. The valve stem 18 is used to control the opening and closing of the ball valve 17. The first gear 19 is sleeved on the outer wall of the valve stem 18 and locked by a set screw. The turbidity sensor 20 is located at the bottom rear side of the inner cavity of the ultrasonic cleaner 1. The turbidity sensor 20 is existing technology and will not be described in detail here. The turbidity sensor 20 is used to measure the turbidity of the cleaning agent. The display 21 is located in the middle front side of the ultrasonic cleaner 1. The display 21 is electrically connected to the turbidity sensor 20. The display 21 is used to display the value monitored by the turbidity sensor 20.

[0038] As a preferred embodiment, the reset mechanism 7 further includes: a bracket 71, a drive cavity 72, a second pressing rod 73, a sleeve 74, a sliding column 75, a rotating rod 76, a drive column 77, a drive groove 78, and a second gear 79. The bracket 71 is located at the bottom right side of the ultrasonic cleaner 1. The electronic counter reset button 16 is located inside the bracket 71. The drive cavity 72 is opened on the right side of the bracket 71. The second pressing rod 73 is located on the left side of the drive cavity 72. The second pressing rod 73 slidably extends into the inner cavity of the bracket 71. The position of the second pressing lever 73 corresponds to the position of the electronic counter reset button 16. The outer wall of the second pressing lever 73 is racetrack-shaped. The second pressing lever 73 is used to press the electronic counter reset button 16. The sleeve 74 is located at the right end of the second pressing lever 73. The sleeve 74 can drive the second pressing lever 73 to move. The distance between the left side of the sleeve 74 and the left side of the inner cavity of the drive cavity 72 is greater than the distance between the left end of the second pressing lever 73 and the right side of the electronic counter reset button 16, ensuring that the second pressing lever 73 can press the electronic counter. The device includes a reset button 16 and two sliding pins 75, which are respectively located at the front and rear ends of the right side of the inner wall of the sleeve 74. When the drive pin 77 rotates, the sleeve 74 can be moved by the cooperation between the drive groove 78 and the sliding pin 75. The rotating rod 76 is located in the middle of the right side of the bracket 71, and the left end of the rotating rod 76 extends rotatably into the inner cavity of the drive cavity 72. The drive pin 77 is located at the left end of the rotating rod 76 and is slidably and rotatably inserted into the inner cavity of the sleeve 74. The outer wall of the drive pin 77 is located at the front and rear ends. Both sides are provided with drive grooves 78. The sliding column 75 is slidably fitted into the right side of the inner cavity of the drive groove 78. The drive column 77 can drive the drive groove 78 to rotate. The distance between the right side and the left side of the inner cavity of the drive groove 78 is greater than the distance between the left end of the second pressing rod 73 and the right side of the electronic counter reset button 16, ensuring that the second pressing rod 73 can press the electronic counter reset button 16. The second gear 79 is sleeved on the outer wall of the rotating rod 76 and locked by a set screw. The second gear 79 meshes with the first gear 19.

[0039] As a preferred embodiment, the dispensing mechanism 8 further includes: a liquid tank 81, a liquid level window 82, a liquid inlet 83, a mounting bracket 84, a jacket 85, a piston cylinder 86, a piston 87, a piston rod 88, an electric telescopic rod 89, a first one-way valve 810, a liquid delivery pipe 811, and a second one-way valve 812. The liquid tanks 81 are multiple, and are equidistantly arranged at the rear bottom of the ultrasonic cleaner 1 along the left-right direction. A liquid level window 82 is provided on the rear side of each liquid tank 81 along the up-down direction. A liquid inlet 83 is provided at the rear top of the tank 81. The liquid tank 81 is used to store cleaning agent. Several mounting brackets 84 are provided, equidistantly arranged at the rear top of the ultrasonic cleaner 1 along the left and right directions. Each mounting bracket 84 corresponds to a liquid tank 81. A clamp 85 is provided at the front bottom of the mounting bracket 84. The piston cylinder 86 can be mounted on the mounting bracket 84 using the clamp 85. The piston cylinder 86 is detachably and appropriately inserted into the inner cavity of the clamp 85. The piston cylinder 86 is used to transfer cleaning agent. 7 is slidably fitted into the bottom end of the inner cavity of the piston cylinder 86. The piston rod 88 is located at the top end of the piston 87, and the top end of the piston rod 88 slidably extends out of the top end of the piston cylinder 86. The piston rod 88 is used to drive the piston 87 to move. The electric telescopic rod 89 is located at the top end of the mounting bracket 84, and the bottom end of the electric telescopic rod 89 is located at the top end of the piston rod 88. The electric telescopic rod 89 is prior art and will not be described in detail here. The electric telescopic rod 89 is used here to drive the piston rod 88 to move. First one-way valve 810 The first one-way valve 810, which is prior art, is located at the bottom of the outer wall of the piston cylinder 86 and will not be described in detail here. The first one-way valve 810 is used to control the flow direction of the cleaning agent. The top end of the infusion tube 811 is located at the bottom of the inner cavity of the piston cylinder 86, and the bottom end of the infusion tube 811 extends into the bottom of the inner cavity of the liquid tank 81. The second one-way valve 812 is located in the middle of the outer wall of the infusion tube 811 and is prior art. The second one-way valve 812 is used to control the flow direction of the cleaning agent.

[0040] Its detailed connection method is a well-known technology in this field. The following mainly introduces the working principle and process, and the specific work is as follows.

[0041] Step 1: During use, the cleaning agent is supplied into the inner cavity of the liquid tank 81 through the liquid inlet 83, ensuring that the cleaning agent in each liquid tank 81 is different. The mesh basket 10 is removed from the inner cavity of the ultrasonic cleaner 1. The electronic counter 15 is activated, and clean water is supplied into the inner cavity of the ultrasonic cleaner 1 through the water inlet pipe 3 until an appropriate amount of clean water is stored in the ultrasonic cleaner 1. The appropriate cleaning agent is selected according to the type of equipment to be cleaned. The electric telescopic rod 89 corresponding to the liquid tank 81 containing the cleaning agent is activated. The electric telescopic rod 89 drives the piston rod 88 upward, which in turn drives the piston 87 upward. Under pressure, the cleaning agent in the liquid tank 81 flows into the piston cylinder 86 through the infusion pipe 811. The piston 87 moves to a suitable height according to the required amount of cleaning agent. At this time, the piston cylinder 86 contains an appropriate amount of cleaning agent. The electric telescopic rod 89 is activated again, and the electric telescopic rod 89 pushes the piston rod 88 to move the piston 87 downward. Thus, the piston 87 can squeeze the cleaning agent in the piston cylinder 86 through the bottom of the piston cylinder 86 into the inner cavity of the ultrasonic cleaner 1, and mix with the clean water in the inner cavity of the ultrasonic cleaner 1 to complete the cleaning agent preparation.

[0042] Step 2: Place the instruments to be cleaned into the inner cavity of the mesh basket 10, put the mesh basket 10 into the inner cavity of the ultrasonic cleaner 1, and make the support rod 9 insert into the inner cavity of the hook 11. The support rod 9 can support the mesh basket 10, so that the support rod 9 can be pressed down by the gravity of the mesh basket 10, and the spring 6 is compressed and deformed elastically. The downward movement of the support rod 9 can drive the first pressing rod 12 to move down, so that the first pressing rod 12 can press the electronic counter counting button 13, causing the count on the electronic counter 15 to increment by one. The electronic counter 15 can then record the number of times the cleaning agent is used in the ultrasonic cleaner 1.

[0043] Step 3: The turbidity sensor 20 can detect the turbidity of the cleaning agent and display the turbidity value on the display 21. When the turbidity sensor 20 detects a high level of turbidity in the cleaning agent, or when the value recorded on the electronic counter 15 reaches a certain value, the cleaning agent in the ultrasonic cleaner 1 needs to be replaced. Rotating the rotating rod 76 drives the second gear 79 and the drive column 77 to rotate counterclockwise. The rotation of the second gear 79, in conjunction with the first gear 19, drives the valve stem 18 to rotate. Thus, the rotation of the valve stem 18 controls the opening and closing of the ball valve 17, and the drive column 77 rotates counterclockwise. The rotation of the needle can drive the drive groove 78 to rotate counterclockwise. The counterclockwise rotation of the drive groove 78 and the sliding column 75 can drive the sleeve 74 to move the second pressing rod 73 to the left until the second pressing rod 73 presses the electronic counter reset button 16, thereby resetting the count on the electronic counter 15 to zero and entering a new recording cycle. At this time, the ball valve 17 is fully opened, and the cleaning agent in the inner cavity of the ultrasonic cleaner 1 can flow into the inner cavity of the ultrasonic cleaner 1 through the drain pipe 4. After the cleaning agent in the inner cavity of the ultrasonic cleaner 1 is emptied, the rotating rod 76 is rotated clockwise to make the movement in the opposite direction.

[0044] This device automatically records the number of times the cleaning agent is used and intelligently monitors the turbidity of the cleaning agent, ensuring that the cleaning agent is always in a highly efficient cleaning state. It avoids the decline in cleaning ability caused by the aging or improper replacement of the cleaning agent, which would affect the cleanliness during the drug development process. It significantly improves the cleaning efficiency and quality of instruments, and protects the safety of staff and the accuracy of the drug development process.

[0045] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device cleaning apparatus for pharmaceutical research and development, characterized in that, include: An ultrasonic cleaner (1) has movable grooves (2) on the top left and right sides of the front and rear sides along the vertical direction. Water inlet pipe (3), the water inlet pipe (3) is located at the top left side of the ultrasonic cleaner (1); Drain pipe (4), the drain pipe (4) is located at the bottom right side of the ultrasonic cleaner (1); Guide rod (5), the upper and lower ends of the guide rod (5) are respectively set on the upper and lower sides of the inner cavity of the moving groove (2); Spring (6), the spring (6) is sleeved on the outer wall of the guide rod (5), and the bottom end of the spring (6) is engaged with the bottom end of the inner cavity of the moving groove (2); The four corners of the outer wall of the support rod (9) are slidably fitted into the top of the inner cavity of the four moving slots (2), the outer wall of the support rod (9) is slidably sleeved on the top of the outer wall of the guide rod (5), and the top of the spring (6) is snapped into the outer wall of the support rod (9). The top of the first pressing rod (12) is located at the middle of the front side of the outer wall of the support rod (9); Reset mechanism (7), the reset mechanism (7) is located at the bottom right side of the ultrasonic cleaner (1); A dispensing mechanism (8) is located on the rear side of the ultrasonic cleaner (1); The outer walls of the basket (10) are respectively attached to the outer walls of the support rod (9) on the left and right sides. The basket (10) is embedded in the inner cavity of the ultrasonic cleaner (1). A ball valve (17) is disposed on the outer wall of the drain pipe (4); Valve stem (18), which is located on the right side of the ball valve (17); The first gear (19) is sleeved on the outer wall of the valve stem (18) and locked by a set screw; An electronic counter counting button (13) is located in the middle of the front side of the ultrasonic cleaner (1). The position of the electronic counter counting button (13) corresponds to the position of the first pressing rod (12), and the electronic counter counting button (13) is located below the first pressing rod (12). An electronic counter (15) and an electronic counter counting button (13) are electrically connected.

2. The instrument cleaning device for pharmaceutical research and development according to claim 1, characterized in that, The instrument cleaning device for pharmaceutical research and development also includes hooks (11), and the number of hooks (11) is four. The four hooks (11) are respectively set at the bottom front and rear sides and left and right ends of the basket (10). The outer wall of the support rod (9) is adapted to be inserted into the inner cavity of the hook (11).

3. The instrument cleaning device for pharmaceutical research and development according to claim 1, characterized in that, The instrument cleaning device for pharmaceutical research and development also includes: The protective shell (14) is located in the middle of the front side of the ultrasonic cleaner (1). The electronic counter counting button (13) is located in the inner cavity of the protective shell (14). The bottom end of the first pressing rod (12) extends slidably into the inner cavity of the protective shell (14). The electronic counter (15) is located in the front side of the protective shell (14). An electronic counter reset button (16) is located at the bottom right side of the ultrasonic cleaner (1). The electronic counter reset button (16) and the electronic counter (15) are electrically connected.

4. The instrument cleaning device for pharmaceutical research and development according to claim 3, characterized in that, The reset mechanism (7) includes: The bracket (71) is located at the bottom right side of the ultrasonic cleaner (1). The electronic counter reset button (16) is located in the inner cavity of the bracket (71). The right side of the bracket (71) has a drive cavity (72). The second pressing rod (73) is located on the left side of the inner cavity of the drive cavity (72). The second pressing rod (73) extends slidably into the inner cavity of the bracket (71). The position of the second pressing rod (73) corresponds to the position of the electronic counter reset button (16). The outer wall of the second pressing rod (73) is racetrack shaped. Sleeve (74), the sleeve (74) is disposed at the right end of the second pressing rod (73); Sliding column (75), the number of the sliding column (75) is two, and the two sliding columns (75) are respectively set at the front and rear ends of the right side of the inner wall of the sleeve (74); A rotating rod (76) is located in the middle of the right side of the bracket (71), and the left end of the rotating rod (76) extends rotatably into the inner cavity of the drive cavity (72); The drive column (77) is located at the left end of the rotating rod (76). The drive column (77) is slidably and rotatably inserted into the inner cavity of the sleeve (74). The drive column (77) has drive grooves (78) on both the front and rear sides of its outer wall. The sliding column (75) is slidably and appropriately inserted into the right side of the inner cavity of the drive groove (78).

5. The instrument cleaning device for pharmaceutical research and development according to claim 4, characterized in that, The outer wall of the rotating rod (76) is fitted with a second gear (79) and locked by a set screw. The second gear (79) meshes with the first gear (19).

6. The instrument cleaning device for pharmaceutical research and development according to claim 5, characterized in that, The dispensing mechanism (8) includes: Liquid tank (81), the number of liquid tanks (81) is several, the several liquid tanks (81) are equidistantly arranged at the rear bottom of the ultrasonic cleaner (1) along the left and right directions, the rear side of the liquid tank (81) is provided with a liquid level window (82) along the up and down direction, and the rear top of the liquid tank (81) is provided with a liquid inlet (83). Mounting bracket (84), there are several mounting brackets (84), and several mounting brackets (84) are equidistantly arranged on the rear side of the top of the ultrasonic cleaner (1) in the left and right directions. The mounting brackets (84) and liquid tanks (81) correspond one to one. A sleeve (85) is disposed at the bottom front end of the mounting bracket (84); Piston cylinder (86), which is detachably adapted to be inserted into the inner cavity of the jacket (85); Piston (87), which is slidably adapted to be inserted into the bottom end of the inner cavity of piston cylinder (86); A piston rod (88) is disposed at the top of the piston (87), and the top of the piston rod (88) extends slidably out of the top of the piston cylinder (86); An electric telescopic rod (89) is provided at the top of the mounting bracket (84), and the bottom end of the electric telescopic rod (89) is provided at the top of the piston rod (88); The first check valve (810) is disposed at the bottom of the outer wall of the piston cylinder (86); An infusion tube (811) is provided at the bottom of the inner cavity of the piston cylinder (86), and the bottom of the infusion tube (811) extends into the bottom of the inner cavity of the liquid tank (81). The second check valve (812) is located in the middle of the outer wall of the infusion tube (811).

7. The instrument cleaning device for pharmaceutical research and development according to claim 6, characterized in that, The ultrasonic cleaner (1) also has the following features installed inside its cavity: Turbidity sensor (20), the turbidity sensor (20) is disposed at the bottom rear side of the inner cavity of the ultrasonic cleaner (1); The display (21) is located in the middle of the front side of the ultrasonic cleaner (1), and the display (21) is electrically connected to the turbidity sensor (20).

8. The instrument cleaning device for pharmaceutical research and development according to claim 7, characterized in that, After the basket (10) containing the instrument is placed into the ultrasonic cleaner (1), the weight of the basket (10) causes the support rod (9) to move down and squeeze the spring (6). The support rod (9) drives the first pressing rod (12) to press the electronic counter counting button (13), so that the electronic counter (15) counts by one, realizing the recording of the number of uses.

9. The instrument cleaning device for pharmaceutical research and development according to claim 8, characterized in that, When the turbidity of the cleaning agent is high or the electronic counter (15) counts to the threshold, rotate the rotating rod (76) to drive the second gear (79) and the drive column (77) to rotate. The second gear (79) meshes with the first gear (19) to open the ball valve (17) to discharge the cleaning agent. The drive column (77) drives the second pressing rod (73) to press the electronic counter reset button (16) to make the electronic counter (15) count to zero.

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