Traditional Chinese medicine composition for treating kidney deficiency enuresis of elderly women by collapse

By using a combination of traditional Chinese medicines such as Dioscorea hypoglauca, Alpinia oxyphylla, Acorus tatarinowii, Lindera strychnifolia, Prunus persica, Carthamus tinctorius, and Paeonia lactiflora for urinary incontinence, combined with infrared irradiation from a TDP therapy device, the problem of insufficient targeted treatment and limited efficacy of drug combinations for kidney deficiency and enuresis in elderly women has been solved, achieving significant therapeutic effects.

CN120983575APending Publication Date: 2025-11-21王杨
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Patent Information

Application Number
CN202511213794.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-28
Publication Date
2025-11-21

AI Technical Summary

Technical Problem

Current technologies for treating enuresis due to kidney deficiency in elderly women lack targeted drug combinations, resulting in limited efficacy and failing to fully consider the mechanism of action of tonifying the kidney and consolidating its function.

Method used

A combination of traditional Chinese medicines, including Dioscorea hypoglauca, Alpinia oxyphylla, Acorus tatarinowii, Lindera strychnifolia, Prunus persica, Carthamus tinctorius, and Paeonia lactiflora, is used. The mixture is pulverized into a fine powder and mixed with rice wine to form a paste. This paste is then applied to specific acupoints and combined with infrared irradiation from a TDP therapy device. The treatment lasts for 30 minutes and the course of treatment is 10-14 days.

Benefits of technology

It improved the drug's targeting and efficacy, significantly improved the symptoms of urinary incontinence caused by kidney deficiency in elderly women, and enhanced the targeting and safety of the treatment.

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating kidney-deficiency enuresis of elderly women by collapse, which comprises the following components: yam rhizome, sharpleaf galangal fruit, grassleaf sweelflag rhizome, combined spicebush root, peach kernel, safflower, white paeony root and the like, and paste is formed by a specific preparation method and is used for treating collapse. According to the application, the traditional Chinese medicine theory and modern pharmacological research are combined, the medicine compatibility and the operation process are optimized, and the symptoms such as frequent urination, urgent urination and frequent urination at night are remarkably improved by adopting a method of matching wet compress with TDP therapeutic apparatus irradiation. Key technical links comprise accurate control of medicine crushing particle size, yellow wine blending proportion and irradiation conditions, and safety and curative effect are ensured. The application has the advantages of high drug pertinence, simplicity and convenience in operation, low cost, high patient compliance and the like, is suitable for being popularized in primary medical institutions, and provides a new method for treating kidney deficiency enuresis of old women.
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Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, specifically a pharmaceutical composition for treating enuresis due to kidney deficiency in elderly women using traditional Chinese medicine soaking. Background Technology

[0002] Lower urinary tract symptoms (LUTS) in women are a concept proposed by the IUGA / ICS Association in 2002. They are defined as symptoms subjectively experienced by the patient, usually reported by the patient or their family. LUTS has a high prevalence, increasing with age. Its etiology is complex, clinical manifestations are diverse, and symptoms lack specificity. Although there is no specific disease name in traditional medicine, based on symptoms such as urinary urgency, frequency, difficulty urinating, and incontinence, it can be categorized under "Lin syndrome," "laborious Lin syndrome," "deficient Lin syndrome," "kidney deficiency," and "urinary incontinence." Kidney deficiency and qi weakness, along with bladder dysfunction, are the main pathological characteristics, involving the kidneys and bladder, and also relating to the heart, liver, spleen, lungs, and triple burner.

[0003] Current treatments for related diseases include traditional Chinese medicine, acupuncture, electroacupuncture, acupoint massage, and acupoint application, which have some effect in relieving symptoms and improving patients' quality of life. However, existing technologies still have shortcomings in treating bedwetting caused by kidney deficiency in elderly women.

[0004] Patent CN205624493U discloses a suspender garment for traditional Chinese medicine treatment. This suspender garment enhances the therapeutic effect by fixing a traditional Chinese medicine pack to the affected area. It is simple to operate and convenient to use. However, the selection of traditional Chinese medicine ingredients in this solution is too broad and has not been optimized for the specific pathological mechanism of kidney deficiency and enuresis in elderly women, making it difficult to accurately meet the needs of a specific population.

[0005] Patent CN202761688U discloses a traditional Chinese medicine pain relief device that integrates multiple therapies such as medicinal wine, moxibustion, and hot compress, making up for the shortcomings of single therapies and applicable to the treatment of various diseases. However, this solution mainly focuses on the pain relief function, paying less attention to the specific condition of kidney deficiency and enuresis, and failing to fully consider the mechanism of action of tonifying the kidney and consolidating the kidney, thus its functionality is relatively limited.

[0006] In summary, existing technologies for treating enuresis due to kidney deficiency in elderly women have limitations in terms of drug combination targeting and functional design, and further optimization is needed to improve efficacy and applicability. Summary of the Invention

[0007] The purpose of this invention is to provide a traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women, in order to solve the problems mentioned in the background art.

[0008] To achieve the above objectives, the present invention provides the following technical solution: a traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women, comprising the following components: Dioscorea hypoglauca 15 to 20 grams; 15 to 20 grams of Alpinia oxyphylla; 15 to 20 grams of Acorus tatarinowii; Lindera root 10 to 15 grams; 10 to 15 grams of peach kernels; 10 to 15 grams of safflower; White peony root 15 to 20 grams.

[0009] Preferably, the pharmaceutical composition is pulverized into traditional Chinese medicine powder by a pulverizer, and the powder particle size is between 80 mesh and 120 mesh.

[0010] Preferably, rice wine and Chinese herbal powder are mixed in a mass ratio of 1:3 to 1:2, and the rice wine is poured in while stirring to form a uniform and moist paste.

[0011] Preferably, the above-mentioned paste is placed in a sterile container for later use.

[0012] Preferably, the patient is placed in a supine position, exposing the periumbilical and lower abdominal area, with a disposable diaper underneath.

[0013] Preferably, the prepared herbal paste is evenly applied to the patient's periumbilical region and lower abdomen, covering the Shenque (CV8), Guanyuan (CV4), Qihai (CV6), and Shuifen (CV9) acupoints.

[0014] Preferably, turn on the TDP therapy device, adjust the irradiation distance to 25 cm to 30 cm, and irradiate the wet compress area for 30 minutes.

[0015] Preferably, the irradiation distance of the TDP therapy device is 25 cm to 30 cm, and the irradiation time is 30 minutes.

[0016] Compared with the prior art, the beneficial effects of the present invention are: the traditional Chinese medicine composition for urination and the treatment method provided in this application, through the optimization of drug compatibility, operation process and key technical links, solve the problems of insufficient drug targeting and limited efficacy in the treatment of enuresis due to kidney deficiency in elderly women, and provide new ideas and methods for the treatment of related diseases. Detailed Implementation

[0017] The technical solutions in the embodiments of the present invention have been clearly and completely described. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0018] Example 1: This application provides a traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women. The composition comprises the following components: 15-20g of Dioscorea hypoglauca, 15-20g of Alpinia oxyphylla, 15-20g of Acorus tatarinowii, 10-15g of Lindera strychnifolia, 10-15g of Prunus persica, 10-15g of Carthamus tinctorius, and 15-20g of Paeonia lactiflora. The selection of these components is based on a combination of traditional Chinese medicine theory and modern pharmacological research results.

[0019] S10: Accurately weigh the above components according to the specified mass range, and pulverize them into fine powder using a pulverizer, ensuring that the powder particle size is between 80 mesh and 120 mesh. In actual operation, the pulverization process requires control of the equipment's operating time and speed to avoid over-pulverization, which could result in powder that is too fine or uneven.

[0020] For example, a small high-speed pulverizer for laboratory use can be selected, with the rotation speed set to 10,000 to 15,000 revolutions per minute and the pulverization time to 3 to 5 minutes. After completion, the powder that meets the particle size requirements can be screened through a sieve.

[0021] S20: Take an appropriate amount of rice wine and pour it slowly into the Chinese medicine powder at a mass ratio of 1:3 to 1:2, stirring constantly until a uniform and moist paste is formed.

[0022] During the mixing process, non-metallic stirring tools (such as wooden or plastic stirring rods) should be used to avoid introducing metal ions that could contaminate the medication. Furthermore, the mixing time should be controlled between 5 and 10 minutes to ensure thorough mixing and a suitable paste consistency.

[0023] S30: Place the above paste in a sterile container for later use. The sterile container must be pre-sterilized at high temperature (e.g., autoclave at 121°C for 30 minutes) and used after cooling. The paste must be sealed during storage and used within 24 hours to avoid changes in the drug composition due to prolonged storage.

[0024] Example 2: This application provides a method for treating enuresis due to kidney deficiency in elderly women using traditional Chinese medicine soaking, including the following steps: S40: The patient should be placed in a supine position, exposing the periumbilical and lower abdominal area. A disposable sheet should be placed underneath to prevent medication from staining clothing or sheets. The private parts should be covered with a screen to protect the patient's privacy. Before the procedure, ensure the patient's skin is clean, dry, and free of any breaks or other abnormalities.

[0025] S50: Apply the prepared herbal paste evenly to the patient's periumbilical region and lower abdomen, covering the acupoints Shenque (CV8), Guanyuan (CV4), Qihai (CV6), and Shuifen (CV9). The application thickness should be controlled between 2 and 3 millimeters to ensure the medication can fully act on the target acupoints. Use a sterile scraper or medical cotton swab for assistance during application to avoid direct contact with the medication using your hands.

[0026] S60: Turn on the TDP therapy device, adjust the irradiation distance to 25-30 cm, and apply local irradiation to the wet compress area for 30 minutes. Before use, check the TDP therapy device to ensure it is functioning correctly and adjust the power output appropriately according to the patient's perceived temperature. For example, initially set a lower power (e.g., 50-70 watts), and gradually increase to the standard power (e.g., 80-100 watts) as the patient adapts.

[0027] This application provides key technical aspects of traditional Chinese medicine poultice therapy for enuresis due to kidney deficiency in elderly women, including the following: Drug pulverization: The particle size must be strictly controlled during the drug pulverization process to ensure that the powder particle size is between 80 and 120 mesh. If the powder is too coarse, it will be difficult to distribute evenly and affect the absorption effect; if the powder is too fine, it may increase the drug's irritation. Therefore, in actual operation, the pulverization equipment needs to be calibrated regularly, and the powder particle size needs to be observed under a microscope to see if it meets the requirements.

[0028] Mixing ratio: The mass ratio of rice wine to Chinese herbal powder needs to be precisely controlled between 1:3 and 1:2. If the ratio is too low, the paste may be too thin and difficult to adhere to the skin surface; if the ratio is too high, the paste may be too viscous and affect the drug's penetration ability. Therefore, in practice, an electronic balance should be used to accurately weigh the rice wine and Chinese herbal powder, and the mixing ratio data should be recorded each time for traceability.

[0029] Irradiation conditions: The irradiation distance of the TDP therapy device should be maintained within the range of 25 cm to 30 cm. If the distance is too close, it may cause excessive local temperature and burns; if the distance is too far, it may reduce the penetration depth of infrared rays and affect the therapeutic effect. In addition, the irradiation time must be strictly controlled at 30 minutes and should not be arbitrarily extended or shortened to maintain the stability of the treatment effect.

[0030] Treatment schedule: Each treatment session lasts 30 minutes, once daily, for 10 to 14 days as one course of treatment. Depending on the severity of the patient's condition, one to three courses of treatment may be required. When undergoing multiple courses of treatment, a 7 to 10-day interval should be maintained before starting the next course to avoid putting a burden on the skin due to prolonged continuous treatment.

[0031] Precautions: During TDP therapy, the patient's skin reaction must be closely monitored to prevent burns caused by excessive temperature. If redness or a burning sensation occurs, irradiation should be stopped immediately and cooling measures should be taken, such as applying a cold compress to the affected area.

[0032] Before treatment, it is necessary to inquire about the patient's allergy history in detail. During the treatment process, pay attention to skin changes. If allergic reactions such as redness, swelling, itching, or blisters occur, remove the medication immediately and clean the skin. If necessary, administer anti-allergy medication.

[0033] During treatment, patients should avoid spicy, raw, cold, greasy, and other irritating foods to prevent affecting the treatment's effectiveness. It is also recommended that patients maintain a regular sleep schedule and engage in appropriate low-intensity exercise to improve their physical condition.

[0034] Traditional Chinese medicine poultice treatment for enuresis due to kidney deficiency in elderly women: Skin allergy: If the patient's skin becomes red, swollen, itchy, burning, or even blisters and peeling, the treatment should be stopped immediately, the medication removed, and the skin cleaned with water. Mild symptoms can be relieved with cold compresses; severe symptoms require prompt medical attention and treatment with anti-allergy medication.

[0035] Burns: If a patient suffers burns due to excessively close proximity or prolonged exposure to the TDP therapy device, the treatment must be stopped immediately. For minor burns, apply burn ointment to the affected area and keep it clean and dry; for severe burns, seek medical attention promptly for professional treatment.

[0036] The Chinese version of the OABSS questionnaire was used to assess four main symptoms of OAB (occurring urinary frequency, nocturia, urgency, and urge incontinence) through a questionnaire. The sum of the scores for the four questions was the total OABSS score. For patients with good adherence who completed two or more courses of treatment, any adverse reactions during medication were carefully inquired about, and if any occurred, the symptoms were recorded. Emphasis was placed on improving urinary urgency symptoms, and changes in OABSS scores before and after treatment were observed and compared. The severity of OAB was graded according to the following criteria: a total OABSS score ≤ 5 indicated mild, a total OABSS score of 6–11 indicated moderate, and a total OABSS score ≥ 12 indicated severe.

[0037] Data were analyzed using SPSS 16.0 statistical software. Quantitative data were expressed as mean ± standard deviation (x ± s), and t-tests were used. A p-value < 0.05 was considered statistically significant.

[0038]

[0039] The traditional Chinese medicine composting drug composition and its treatment method have the following characteristics: the drug selection is highly targeted, the operation is simple and easy, and the safety is high.

[0040] Traditional Chinese medicine plastering drug compositions and their treatment methods have broad application prospects: the applicable population is clearly defined, and the therapeutic effect is significant.

[0041] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women, characterized in that, Includes the following components: Dioscorea hypoglauca 15 to 20 grams; 15 to 20 grams of Alpinia oxyphylla; 15 to 20 grams of Acorus tatarinowii; Lindera root 10 to 15 grams; 10 to 15 grams of peach kernels; 10 to 15 grams of safflower; White peony root 15 to 20 grams.

2. The traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women according to claim 1, characterized in that, The pharmaceutical composition is pulverized into traditional Chinese medicine powder by a pulverizer, with a particle size between 80 mesh and 120 mesh.

3. The traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women according to claim 2, characterized in that: Mix rice wine and Chinese herbal powder in a mass ratio of 1:3 to 1:2, and pour in the rice wine while stirring to form a uniform and moist paste.

4. The traditional Chinese medicine composition for treating enuresis due to kidney deficiency in elderly women according to claim 3, characterized in that: Place the above paste in a sterile container for later use.

5. A method for treating patients using the traditional Chinese medicine soaking composition as described in claim 4, characterized in that: The patient is placed in a supine position, exposing the periumbilical and lower abdominal area, with a disposable sheet placed underneath.

6. The operating method according to claim 5, characterized in that: Apply the prepared herbal paste evenly to the patient's navel and lower abdomen, covering the Shenque (CV8), Guanyuan (CV4), Qihai (CV6), and Shuifen (CV9) acupoints.

7. The operating method according to claim 6, characterized in that: Turn on the TDP therapy device, adjust the irradiation distance to 25 cm to 30 cm, and apply local irradiation to the wet compress area for 30 minutes.

8. The operating method according to claim 7, characterized in that: The TDP therapy device has an irradiation distance of 25 to 30 centimeters and an irradiation time of 30 minutes.

Citation Information

Patent Citations

  • Traditional Chinese medicine treatment pain relieving device

    CN202761688U

  • Treatment by chinese herbs is with hanging trousers

    CN205624493U