Sample analysis system

Abstract

The invention relates to a sample analysis system which comprises at least two specific protein analyzers, a sample transfer device and a control device, the sample transfer device comprises a transmission mechanism with a transmission channel and at least two feeding mechanisms with detection channels, each specific protein analyzer corresponds to one feeding mechanism, and the detection channels are communicated with the transmission mechanism. And the detection area of each specific protein analyzer corresponds to the detection channel of the corresponding feeding mechanism. And the control equipment is used for controlling the sample transfer equipment to transfer the to-be-detected sample rack on which the sample container needing to be subjected to specific protein detection is placed to one of the specific protein analyzers. According to the sample analysis system, one specific protein analyzer is selected from the at least two specific protein analyzers to detect the to-be-detected sample frames needing specific protein detection at present, the to-be-detected sample frames can be reasonably distributed, the speed requirement for a specific protein measurement module can be reduced, the measurement requirement for a large sample size can be met, and the measurement efficiency is improved. The specific protein measurement efficiency is improved.

Description

[0001] This application is a divisional application of the invention patent application with the application date of February 21, 2020, the application number of 202010108560.4, and the invention name of "Sample analysis system". TECHNICAL FIELD

[0002] The present application relates to the field of medical diagnostic equipment, in particular to a sample analysis system. BACKGROUND

[0003] CRP (C-reactive protein) is an acute phase protein, which exists in small amounts in body fluids under normal circumstances, and increases to varying degrees in infectious diseases, and has important clinical application value. In recent years, with the rapid development of rapid bedside detection technology, CRP has been more widely used in clinical infectious diseases, and has once again become the focus of clinical research.

[0004] Blood routine is one of the three routine examinations, and is also one of the commonly used auxiliary examination methods for doctors to diagnose the condition. Doctors observe the changes in the number of blood cells and the distribution of morphology to assist in judging the body condition. There is a high correlation between the CRP detection result and the blood routine detection result, and the CRP detection is often used by doctors in combination with blood routine for the differentiation of bacterial infection and viral infection due to its simple operation, fast detection speed and small amount of specimen required.

[0005] The existing sample analysis system integrates the blood routine and CRP measurement functions, but is usually composed of a set of detection equipment and multiple blood routine measurement pools and multiple CRP measurement pools. Due to the limitations of instrument cost and volume, the number of blood routine measurement pools and CRP measurement pools is small, and there is only one set of detection equipment, which greatly limits the measurement speed of blood routine and CRP. In clinical practice, basically all samples need to be detected by blood routine, and CRP as an inflammation detection item only accounts for a certain percentage, so a large flux and efficient blood routine measurement device is needed in clinical practice, and a high-speed CRP measurement instrument is needed to cooperate with blood routine and CRP combined detection. SUMMARY

[0006] In order to solve the above technical problems, the present application provides a sample analysis system.

[0007] The first aspect of the present application provides a sample analysis system, comprising: at least two specific protein analyzers for specific protein detection, a sample transfer device, and a control device, wherein the sample transfer device comprises: a transport mechanism having a transport channel, and at least two feeding mechanisms each having a detection channel, the transport mechanism is used to transfer a sample rack having a sample container placed therein in the transport channel, each feeding mechanism is arranged at intervals along the transport direction of the transport channel, and the feeding mechanism can transfer the sample rack from the transport channel to the detection channel and from the detection channel to the transport channel; each specific protein analyzer corresponds to one feeding mechanism, and the detection area of each specific protein analyzer corresponds to the detection channel of the corresponding feeding mechanism; the at least two specific protein analyzers are configured to detect at least one same specific protein; the control device is electrically connected with each specific protein analyzer and the sample transfer device, and is configured to: acquire the running state information of each specific protein analyzer and the measurement mode information of the sample container on the sample rack to be measured, and when the measurement mode information indicates that the sample container requiring specific protein detection is placed on the sample rack to be measured, control the sample transfer device to transfer the sample rack to be measured to the detection area of one of the at least two specific protein analyzers according to the running state information.

[0008] Optionally, the running state information comprises detection load information of each specific protein analyzer; and the control device is configured to control the sample transfer device to transfer the sample rack to be measured to the detection area of the specific protein analyzer with smaller detection load among the at least two specific protein analyzers according to the detection load information of each specific protein analyzer.

[0009] Optionally, the control device is further configured to: determine a waiting time length of the sample rack to be measured according to the detection load information of each specific protein analyzer, and control the sample transfer device to transfer the sample rack to be measured to the detection area of the specific protein analyzer with smaller detection load among the at least two specific protein analyzers after the waiting time length.

[0010] Optionally, the sample analysis system further comprises an unloading platform and other analyzers different from the at least two specific protein analyzers, and the control device is further configured to: when the waiting time length is greater than a preset time length, control the sample transfer device to transfer the sample rack to be measured to the unloading platform or the other analyzers.

[0011] Optionally, the sample analysis system further comprises at least one blood cell analyzer for blood routine test, each blood cell analyzer corresponds to one feeding mechanism, and the detection area of each blood cell analyzer corresponds to the detection channel of the corresponding feeding mechanism.

[0012] Optionally, the at least one blood cell analyzer is located in front of the at least two specific protein analyzers in a transmission direction along the transmission channel.

[0013] Optionally, the at least one blood cell analyzer comprises a scanning device for acquiring measurement mode information of sample containers on the sample rack to be tested; the control device is configured to control the sample transfer device to transfer the sample rack to be tested to one of the blood cell analyzers for first blood routine test and acquire the measurement mode information of sample containers on the sample rack to be tested, and when the measurement mode information indicates that sample containers requiring specific protein test are placed on the sample rack to be tested, control the sample transfer device to transfer the sample rack to be tested after first blood routine test to the detection area of one of the at least two specific protein analyzers according to the running state information.

[0014] Optionally, the at least two specific protein analyzers each comprises a scanning device for confirming measurement mode information of sample containers on the sample rack to be tested.

[0015] Optionally, the sample analysis system further comprises a loading platform located before the at least one blood cell analyzer in a transmission direction along the transmission channel and configured to place a sample rack to be tested, and a platform loading mechanism configured to transfer the sample rack on the loading platform to the transmission channel; the loading platform is provided with a scanning device configured to identify the identification of the sample rack and sample placed on the loading platform, and establish and store the correspondence between the identification of the sample and its position on the sample rack.

[0016] Optionally, the control device is electrically connected to each of the blood cell analyzers and configured to acquire blood routine test data of each of the blood cell analyzers; the control device is further configured to determine a sample container with blood routine test data meeting a preset recheck condition as a recheck sample container, and determine one of the at least one blood cell analyzer as a recheck blood cell analyzer for rechecking the recheck sample container.

[0017] Optionally, the control device is configured to, when the sample rack to be tested comprises a recheck sample container and a sample container requiring specific protein test, control the sample transfer device to first transfer the sample rack to be tested after first blood routine test to the recheck blood cell analyzer for blood routine recheck, and then control the sample transfer device to transfer the sample rack to be tested after blood routine recheck of the recheck sample container to the detection area of one of the at least two specific protein analyzers for specific protein test.

[0018] Optionally, the control device is configured to, when the sample rack to be tested includes a recheck sample container and a sample container requiring specific protein detection, control the sample transfer device to first move the sample rack to be tested to the detection area of one of the at least two specific protein analyzers for specific protein detection, and then move the sample rack to be tested after specific protein detection to the recheck blood cell analyzer for blood routine recheck.

[0019] Optionally, the sample analyzer system includes at least two blood cell analyzers for blood routine detection, and at least one of the at least two blood cell analyzers is located in front of the at least two specific protein analyzers in the transmission direction along the transmission channel.

[0020] Optionally, the at least two blood cell analyzers include at least one high-specification blood cell analyzer and at least one low-specification blood cell analyzer, the detection items of the high-specification blood cell analyzer being different from the detection items of the low-specification blood cell analyzer, and the low-specification blood cell analyzer is located in front of the high-specification blood cell analyzer in the transmission direction along the transmission channel.

[0021] Optionally, the control device is further configured to: be electrically connected to each of the blood cell analyzers and configured to acquire blood routine detection data of each of the blood cell analyzers; determine a sample container whose blood routine detection data meets a preset recheck condition as a recheck sample container and determine a recheck mode of the recheck sample container, the recheck mode including a same-item recheck mode and an added-item recheck mode; when the sample rack to be tested includes a recheck sample container with a recheck mode of the same-item recheck mode, control the sample transfer device to move the sample rack to be tested to a blood cell analyzer that performs first blood routine detection on the recheck sample container for recheck; and when the sample rack to be tested includes a recheck sample container with a recheck mode of the added-item recheck mode, control the sample transfer device to move the sample rack to be tested to the high-specification blood cell analyzer for recheck.

[0022] Optionally, at least one of the at least two specific protein analyzers is located between the low-specification blood cell analyzer and the high-specification blood cell analyzer in the transmission direction along the transmission channel, and the control device is configured to, when the sample rack to be tested includes a recheck sample container with a recheck mode of the added-item recheck mode and a sample container requiring specific protein detection, control the sample transfer device to move the sample rack to be tested to a specific protein analyzer located between the low-specification blood cell analyzer and the high-specification blood cell analyzer for specific protein detection, and control the sample transfer device to move the sample rack to be tested to the high-specification blood cell analyzer for recheck after specific protein detection.

[0023] Optionally, the at least two specific protein analyzers are selected from a C-reactive protein analyzer, a serum amyloid A analyzer, a procalcitonin analyzer, or other specific protein analyzers, or include two or more of them in an all-in-one machine.

[0024] The second aspect of the present application provides a sample analysis system, comprising: one specific protein analyzer for specific protein detection, a sample transfer device, a control device, and at least two blood cell analyzers for blood routine detection, wherein the sample transfer device comprises: a transmission mechanism having a transmission channel, and at least three feeding mechanisms each having a detection channel, the transmission mechanism is used to transfer a sample rack having a sample container placed therein in the transmission channel, each feeding mechanism is arranged at intervals along the transmission direction of the transmission channel, and the feeding mechanism can transfer the sample rack from the transmission channel to the detection channel and from the detection channel to the transmission channel; the specific protein analyzer and each of the blood cell analyzers correspond to one of the feeding mechanisms, and the detection area of the specific protein analyzer and each of the blood cell analyzers respectively corresponds to the detection channel of the corresponding feeding mechanism; along the transmission direction of the transmission channel, the specific protein analyzer is located between the at least two blood cell analyzers; the control device is electrically connected with the sample transfer device and is configured to: acquire measurement mode information of a sample container on a sample rack to be tested, and control the sample transfer device to transfer the sample rack to be tested loaded with a sample to the specific protein analyzer and / or any one of the blood cell analyzers for corresponding detection according to the measurement mode information.

[0025] Optionally, the control device is electrically connected with each of the blood cell analyzers and is configured to acquire blood routine detection data of each of the blood cell analyzers.

[0026] The control device is further configured to determine a sample container whose blood routine detection data meet a preset recheck condition as a recheck sample container, and determine one of the at least two blood cell analyzers as a recheck blood cell analyzer for rechecking the recheck sample container.

[0027] Optionally, the control device is configured to, when the sample rack to be tested includes a recheck sample container and a sample container that needs to be detected for specific protein, control the sample transfer device to first transfer the sample rack to be tested to the recheck blood cell analyzer for blood routine rechecking, and then control the sample transfer device to transfer the sample rack to be tested after the recheck sample container on the sample rack to be tested is rechecked for blood routine to the detection area of the specific protein analyzer for specific protein detection.

[0028] Optionally, the control device is configured to control the sample transfer device to move the sample rack to be tested to the detection area of the specific protein analyzer for specific protein detection when the sample rack to be tested includes the review sample container and the sample container requiring specific protein detection, and then transfer the sample rack to be tested after specific protein detection to the review blood cell analyzer for blood routine review.

[0029] Optionally, the at least two blood cell analyzers include at least one high-specification blood cell analyzer and at least one low-specification blood cell analyzer, the detection items of the high-specification blood cell analyzer are different from the detection items of the low-specification blood cell analyzer, and the low-specification blood cell analyzer is located in front of the high-specification blood cell analyzer in the transmission direction along the transmission channel.

[0030] Optionally, the control device is further configured to: be electrically connected to each blood cell analyzer and configured to acquire blood routine detection data of each blood cell analyzer; determine a sample container whose blood routine detection data meets a preset review condition as a review sample container and determine a review mode of the review sample container, the review mode including a same-item review mode and an added-item review mode; control the sample transfer device to transfer the sample rack to be tested to the blood cell analyzer that performs the first blood routine detection on the review sample container for review when the sample rack to be tested includes the review sample container with the same-item review mode; and control the sample transfer device to transfer the sample rack to be tested to the high-specification blood cell analyzer for review when the sample rack to be tested includes the review sample container with the added-item review mode.

[0031] Optionally, the specific protein analyzer is located behind the low-specification blood cell analyzer and in front of the high-specification blood cell analyzer in the transmission direction along the transmission channel, and the control device is configured to control the sample transfer device to transport the sample rack to be tested to the specific protein analyzer when the sample rack to be tested includes the review sample container with the added-item review mode and the sample container requiring specific protein detection, and control the sample transfer device to transfer the sample rack to be tested to the high-specification blood cell analyzer for review after the specific protein detection is completed.

[0032] The above technical solution provided by the embodiments of the present application has the following advantages compared with the prior art: the sample analysis system can select one specific protein analyzer from at least two specific protein analyzers to detect the sample rack to be tested requiring specific protein detection, so that when there are multiple sample racks to be tested requiring specific protein detection, the sample racks to be tested can be reasonably allocated, the speed requirement of the specific protein measurement module can be reduced, the measurement demand of a large sample amount can be met, and the specific protein measurement efficiency can be improved. BRIEF DESCRIPTION OF DRAWINGS

[0033] The accompanying drawings, which are incorporated herein and form a part of the specification, illustrate embodiments that conform to the present application and, together with the description, further serve to explain the principles of the present application.

[0034] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the accompanying drawings required to be used in the embodiments or prior art description will be briefly introduced as follows. Obviously, for those of ordinary skill in the art, other drawings can also be obtained based on these drawings without any creative effort.

[0035] Figures 1 to 7 A structural schematic diagram of a sample analysis system provided for different embodiments of the present application;

[0036] Figure 8 A structural schematic diagram of a control device provided for an embodiment of the present application. DETAILED DESCRIPTION

[0037] In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be described clearly and completely below with reference to the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments of the present application, all other embodiments obtained by those of ordinary skill in the art without any creative effort fall within the scope of protection of the present application.

[0038] Figure 1 A structural schematic diagram of a sample analysis system provided for an embodiment of the present application.

[0039] As Figure 1 shown, the sample analysis system includes at least two specific protein analyzers (including a first specific protein analyzer 10 and a second specific protein analyzer 20 in the figure) for specific protein detection, a sample transfer device and a control device 30.

[0040] In the embodiments of the present application, the at least two specific protein analyzers are configured to detect at least one same specific protein, and the at least two specific protein analyzers are selected from a C-reactive protein (CRP) analyzer, a serum amyloid A (SAA) analyzer, a procalcitonin (PCT) analyzer or other specific protein analyzers, or an all-in-one machine comprising two or more of the above analyzers. For example, the at least two specific protein analyzers are both analyzers capable of detecting only CRP, or are both all-in-one machines capable of detecting CRP and / or SAA, or one of the specific protein analyzers is an analyzer capable of detecting only CRP, and the other specific protein analyzer is an all-in-one machine capable of detecting CRP and / or SAA.

[0041] The sample transfer device is configured to transfer the sample rack in which the sample container is placed. In the embodiments of the present application, the sample transfer device comprises a transmission mechanism 41 and at least two feeding mechanisms 42 each having a detection channel.

[0042] The transmission mechanism 41 forms a transmission channel in which the sample rack can be moved by the transmission mechanism 41. The feeding mechanisms 42 are arranged on the side of the transmission channel and are spaced apart along the transmission direction X of the transmission channel, and a space is provided between adjacent feeding mechanisms 42. The feeding mechanisms 42 are configured to transfer the sample rack from the transmission channel to the detection channel and from the detection channel to the transmission channel.

[0043] In specific applications, the transmission mechanism 41 can adopt any one or a combination of a chain type mechanism, a track type mechanism, a belt type mechanism, a roller type mechanism and a rail type mechanism. If a combination of multiple mechanisms is adopted, the transmission mechanism 41 can be configured to cooperate with multiple segments of different mechanisms arranged along the transmission channel.

[0044] In the embodiments of the present application, the transmission mechanism 41 can complete the transfer of the sample rack, and the shape of the transmission channel is not limited. For example, the transmission channel can be linear, or can be a broken line with a certain angle, or can be an arc line with a certain curvature, or even an irregular shape.

[0045] In the embodiments of the present application, the transmission channel can be a flat channel, for example, the upper surface of the belt of the belt type mechanism directly serves as the transmission channel. In addition, considering that the sample rack can fall or be twisted in position during the transfer, the transmission channel can also be a semi-enclosed channel, for example, the belt type mechanism is provided with a baffle on both sides of the belt, and the top of the baffle is not closed, so that the area surrounded by the baffle forms a semi-enclosed transmission channel, and the sample rack is constrained by the baffle and cannot fall or be twisted in position. In addition, considering that the sample rack can be placed in disorder after being manually taken during the transfer, the transmission channel can also be a fully enclosed channel, for example, the belt type mechanism is provided with a baffle on both sides and the top of the belt, so that the sample rack cannot be taken by the operator during the transfer in the transmission channel, thereby avoiding manual intervention.

[0046] In the embodiments of the present application, the transmission channel serves as the main channel, and each detection channel serves as a branch channel. During the operation, the transmission mechanism 41 can transfer the sample rack to the position of each feeding mechanism 42 on the transmission channel, and then the sample rack is transferred from the transmission channel to the corresponding detection channel by the feeding mechanism 42, and the feeding mechanism 42 can also transfer the sample rack from the detection channel back to the transmission channel.

[0047] Each specific protein analyzer can be provided with one feeding mechanism 42, and the detection channel of each feeding mechanism 42 corresponds to the position of the detection area of the corresponding specific protein analyzer, for example, the detection channel coincides with the position of the detection area. In this way, when the sample rack moves in the detection channel, the sample rack can move to the detection area of the specific protein analyzer, and then the sample in the sample container on the sample rack can be collected by the specific protein analyzer to detect and analyze the sample.

[0048] In the embodiments of the present application, the feeding mechanism 42 can also adopt any one or a combination of a chain type mechanism, a track type mechanism, a belt type mechanism, a roller type mechanism, and a track type mechanism. If a plurality of combinations are adopted, the feeding mechanism 42 can be provided with a plurality of sections of different mechanisms for cooperation. For the description of the feeding mechanism 42, reference can be made to the foregoing description of the transmission mechanism 41. Details are not described herein.

[0049] In this embodiment, the first specific protein analyzer 10 (e.g., a CRP analyzer capable of detecting C-reactive protein) and the second specific protein analyzer 20 (e.g., a CRP analyzer capable of detecting C-reactive protein) each correspond to a feeding mechanism 42, and the detection areas of the first specific protein analyzer 10 and the second specific protein analyzer 20 correspond to the detection channels of their respective feeding mechanisms 42, so that samples in sample containers on the sample holder can undergo specific protein analysis in either the first specific protein analyzer 10 or the second specific protein analyzer 20. In other embodiments, multiple specific protein analyzers may be provided with the same feeding mechanism, and the detection areas of the multiple specific protein analyzers are arranged along the detection channels of the same feeding mechanism.

[0050] The first specific protein analyzer 10 and the second specific protein analyzer 20 are used to detect specific proteins in samples transferred from the sample transfer device to the sample container on the sample rack in the corresponding detection channel.

[0051] like Figure 1 As shown in this embodiment, the first specific protein analyzer 10 is located in front of the second specific protein analyzer 20 along the transmission direction X of the transmission channel. In some embodiments, the positions of the first specific protein analyzer 10 and the second specific protein analyzer 20 are not limited, and their order can be freely set.

[0052] In this embodiment, "front" and "back" are relative concepts. "Front" refers to the position passed first along the transmission direction X, and "back" refers to the position passed later along the transmission direction X. Therefore, the first specific protein analyzer 10 is located in front of the second specific protein analyzer 20, meaning the sample rack on the transmission channel passes first through the first specific protein analyzer 10 and then through the second specific protein analyzer 20. Figure 1 Taking the direction shown as an example, the transmission direction X is from right to left. Then, "front" refers to the position relatively to the right in the figure, and "back" refers to the position relatively to the left in the figure. Therefore, "front" and "back" in the embodiments of this application describe the relative positional relationship between the first specific protein analyzer 10 and the second specific protein analyzer 20, rather than a simple understanding of the literal meaning. The literal meaning should not constitute a limitation on this application.

[0053] The control device 30 is electrically connected to the first specific protein analyzer 10, the second specific protein analyzer 20, and the sample transfer device, respectively. The control device 30 can be a desktop computer, laptop computer, microcontroller, PDA, or other device with computing capabilities. In this embodiment, the control device 30 is used to acquire the operating status information of each specific protein analyzer and the measurement mode information of the sample containers on the sample rack. The operating status information refers to the information of the specific protein analyzer when it is currently performing specific protein detection on the sample. The operating status information includes at least the detection load information of the specific protein analyzer, that is, the number of sample containers currently assigned to the specific protein analyzer for detection. In other embodiments of this application, the operating status information may also include machine status information, such as fault information, whether it is enabled, etc. Measurement mode information refers to the information about the items that need to be tested in each sample container on the sample rack. Different modes correspond to different testing items. Measurement mode information can be a pre-set mode, which can be received directly via cable / wireless means. Alternatively, the measurement mode can also be obtained by scanning the identification code containing the measurement mode information on the sample container on the sample rack. For example, when the sample is transferred on the sample transfer device, the identification code on the sample container is scanned on site to obtain the measurement mode that needs to be tested in the sample container.

[0054] When the measurement mode information indicates that a sample container requiring specific protein detection is placed on the current sample rack, the control device 30 controls the sample transfer device to transfer the sample rack to the detection area of ​​one of at least two specific protein analyzers, so that the sample container on the sample rack requiring specific protein detection can be detected in the appropriate specific protein analyzer.

[0055] In this embodiment of the application, by setting up multiple specific protein analyzers that can detect the same specific protein, the speed requirements of the specific protein measurement module can be reduced, while meeting the measurement needs of a large sample size and improving the measurement efficiency of specific proteins.

[0056] like Figure 1 As shown, in some embodiments of this application, the feeding mechanism 42 in the sample analysis system further includes: a transmission mechanism 421, a loading buffer area 422, and a loading mechanism 423.

[0057] The transmission mechanism 421 can adopt any one or a combination of a chain type mechanism, a track type mechanism, a belt type mechanism, a roller type mechanism, and a rail type mechanism. If a combination of multiple mechanisms is adopted, the transmission mechanism 421 can be provided with multiple segments of different mechanisms. In the embodiment, the transmission mechanism 421 is formed with a detection channel. The position of the detection channel corresponds to the position of the detection area of the analyzer corresponding to the feeding mechanism 42, so that the sample container transferred in the detection channel can be smoothly detected.

[0058] As shown in Figure 1 The loading buffer area 422 is located between the detection channel and the transmission channel. The loading buffer area 422 is mainly provided to consider that if the number of sample racks transferred by the transmission channel to the analyzer is large, and the analyzer needs to consume a certain amount of time to complete the detection of each sample rack, if all the sample racks on the transmission channel are transferred to the analyzer, the normal detection will be affected. The setting of the loading buffer area 422 can make the sample racks transferred on the transmission channel be buffered in the area first, and then the sample racks buffered in the area are transferred to the detection channel according to the detection speed of the analyzer.

[0059] As shown in Figure 1 The loading mechanism 423 is located at the bottom of the loading buffer area 422, and is used to transfer the sample racks passing through the transmission channel to the loading buffer area 422, and transfer the sample racks in the loading buffer area 422 to the detection channel.

[0060] As shown in Figure 1 The feeding mechanism 42 further includes an unloading buffer area 424 and an unloading mechanism 425. The unloading buffer area 424 is located between the detection channel and the transmission channel, and the unloading buffer area 424 and the loading buffer area 422 are arranged along the transmission direction of the detection channel. For example, the loading buffer area 422 and the unloading buffer area 425 are respectively located at two ends of the detection channel. The unloading mechanism 425 is located in the unloading buffer area, and is used to transfer the sample racks passing through the detection channel to the unloading buffer area 424, and transfer the sample racks in the unloading buffer area 424 to the transmission channel.

[0061] In an embodiment, the running state information includes detection load information of each specific protein analyzer. The detection load information refers to the number of samples currently assigned to each specific protein analyzer for detection.

[0062] In order to further improve the detection efficiency of specific proteins, when the control device 30 controls the sample transfer device to transfer the sample racks to be detected, the control mode can be as follows:

[0063] The control device 30 determines the specific protein analyzers with smaller detection load according to the detection load information of each specific protein analyzer, and then controls the sample transfer device to transfer the current sample rack to be detected to the detection area of the specific protein analyzer with smaller detection load among the at least two specific protein analyzers.

[0064] In this way, the specific protein analyzer with smaller detection load is preferentially selected, so that the detection waiting time of the specific protein on the pipeline is shortened, and the detection efficiency of the specific protein is improved.

[0065] In an embodiment of the present application, the running state information can further include machine state information, such as fault information. For example, when one of the specific protein analyzers fails or needs to replace consumables and / or reagents, the specific protein analyzer can be automatically removed from the sample analyzer system, and the control device 30 no longer schedules the sample rack to be detected to the specific protein analyzer, but schedules the sample rack to be detected to another normally working specific protein analyzer.

[0066] In an embodiment of the present application, when the detection load information of each specific protein analyzer indicates that the corresponding specific protein analyzer is in a busy state (the busy state means that the number of samples to be detected for specific proteins in the specific protein analyzer is greater than the processing capacity of the specific protein analyzer, and the specific protein analyzer needs to work continuously for a period of time before it is idle), on the one hand, if the sample rack to be detected is still transferred to the specific protein analyzer in the busy state, the specific protein analyzer needs to wait for a relatively long time due to the busy state; on the other hand, limited by the limited space of the feeding mechanism corresponding to the specific protein analyzer, once the number of sample racks accommodated in the feeding mechanism corresponding to the specific protein analyzer in the busy state is saturated, there will be no extra idle position in the feeding mechanism corresponding to the specific protein analyzer in the busy state to accommodate new sample racks. Therefore, the control device 30 can first determine the waiting time T1 of the sample rack to be detected before being detected according to the detection load information of each specific protein analyzer, and then start timing, and when the timing time t0=T1, the sample transfer device is controlled to transfer the sample to be detected to the detection area of the specific protein analyzer with smaller detection load among the at least two specific protein analyzers.

[0067] In an embodiment of the present application, the sample analysis system can further include an unloading platform and other analyzers different from the at least two specific protein analyzers. The unloading platform can be located at the end of the transfer direction of the transfer device, that is, at the end of the X direction. The other analyzers can be blood cell analyzers, glycosylation analyzers, push-piece staining machines, etc. The positions of the other analyzers and the at least two specific protein analyzers can be freely set. For example, as shown in FIG. 1, the other analyzers can be located on the left side of the at least two specific protein analyzers. Figure 2As shown, the blood cell analyzer 60 is located in front of the first specific protein analyzer 10 and the second specific protein analyzer 20 along the transmission direction of the transmission channel, and the push piece staining machine 50 is located behind the second specific protein analyzer 20. As shown in Figure 2 As shown, the sample analysis system further comprises an unloading platform 80 for placing the sample racks. The unloading platform 80 is arranged at one end of the transmission channel, and the sample racks on the transmission channel can be all transmitted to the unloading platform 80 for storage. Figure 2 The unloading platform 80 is arranged at the end of the transmission direction X of the transmission channel. The sample racks on the transmission channel can all be transmitted to the unloading platform 80 for storage.

[0068] In addition, referring to Figure 2 As shown, the sample analysis system further comprises a platform unloading mechanism 81 for transferring the sample racks in the transmission channel to the unloading platform 80, and optionally transferring the samples on the unloading platform 80 to the transmission channel.

[0069] Considering that the transmission channel on the transmission mechanism 41 is shared, if the waiting time T1 of the sample rack to be tested is too long, it may affect the detection speed of the sample container on the sample rack to be tested which needs to be transported to other analyzers for detection of other items (such as glycation or push piece), or cause too many sample racks to be tested to wait for transportation, affecting the efficiency of the sample analysis system, and even causing traffic jams. In order to efficiently multiplex the transmission channel on the transmission mechanism 41, in the embodiments of the present application, if the waiting time T1 is calculated, it can be judged whether the waiting time T1 is greater than a preset time Tx (the preset time Tx can be a time set by the operator himself), when T1 is greater than Tx, the specific protein analyzer of the sample analysis system is still in a busy state, at this time the control device 30 can control the sample transfer device to transfer the sample rack to be tested to the unloading platform or other analyzers, that is, to skip the specific protein detection of the sample rack to be tested, and unload to the unloading platform or transport to other analyzers for measurement first.

[0070] The current sample rack to be tested is moved to the unloading platform or other analyzers, so that the transmission channel of the transfer device is not occupied, and other sample racks to be tested are conveniently transferred, and the transmission efficiency of the transmission channel is improved. For example, when the sample rack to be tested is waiting on the unloading platform, the detection load information of the specific protein analyzer can be continuously monitored. When the specific protein detection condition is met, the sample rack to be tested is moved from the unloading platform back to the transmission channel, and then the sample rack to be tested is moved to the corresponding specific protein analyzer for detection by the transmission mechanism 41. For example, if the samples in the current sample rack to be tested still have other detection items in addition to specific protein detection, the sample transfer device can be controlled by the control device 30 to move the current sample rack to be tested to other analyzers in the transmission channel. Moving to other analyzers can facilitate detection of other detection items of the samples in the sample container on the current sample rack to be tested, and the waiting time for specific protein detection of the current sample rack to be tested can be used to detect other detection items, thereby improving the overall detection efficiency of samples with multiple detection items.

[0071] In an embodiment of the present application, the sample analysis system can further include at least one blood cell analyzer, preferably at least two blood cell analyzers, for blood routine detection. Each blood cell analyzer corresponds to one feeding mechanism 42, and the detection area of each blood cell analyzer corresponds to the detection channel of its corresponding feeding mechanism 42. In some embodiments, at least one blood cell analyzer is located in front of at least two specific protein analyzers in the transmission direction along the transmission channel. As shown in Figure 4 The blood cell analyzer 60 is included in the figure and is located in front of the first specific protein analyzer 10 in the transmission direction X.

[0072] In an embodiment of the present application, by providing multiple specific protein analyzers and at least one blood cell analyzer, the specific protein measurement speed can be matched with the blood routine measurement speed, thereby reducing the risk of traffic jams in the sample analyzer system due to the faster blood routine measurement speed than the specific protein detection speed.

[0073] If the sample analysis system only has at least two specific protein analyzers, i.e., the sample analysis system only performs specific protein detection, then all sample containers on the sample rack to be tested placed in the sample analysis system need to be subjected to specific protein detection. Therefore, the specific protein analyzer only needs to perform specific protein detection on each sample container moved to its detection area. If the sample analysis system further includes at least one blood cell analyzer, the sample analysis system will no longer be used only for specific protein detection, but can also perform blood routine detection.

[0074] Therefore, for each sample container in the sample rack to be tested placed in the sample analysis system, the measurement mode needs to be identified. As shown in Figure 2As shown, the sample analysis system can also generally include a loading platform 70 and a platform loading mechanism 71. The loading platform 70 is located at one end of the transport channel, and is used to place the sample racks to be tested. The loading platform 70 is located at the front end of the transport direction X of the transport channel, i.e., the sample racks are first moved from the loading platform 70 into the transport channel, and then transported through the transport channel to the respective analyzers. The platform loading mechanism 71 is used to move the sample racks on the loading platform 70 to the transport channel. The sample racks to be tested placed on the loading platform 70 are generally first transported to the blood cell analyzer for routine blood testing. For this purpose, in an embodiment of the present application, at least one blood cell analyzer includes a scanning device for acquiring the measurement mode information of the sample containers on the sample rack to be tested as the sample rack to be tested passes through the blood cell analyzer.

[0075] When the measurement mode information indicates that the sample containers on the sample rack to be tested need to be tested for specific proteins, the control device 30 controls the sample moving device to move the sample rack to be tested that has undergone routine blood testing, e.g., first routine blood testing, to the detection area of one of the at least two specific protein analyzers according to the operating state information.

[0076] That is, the sample rack to be tested is first placed on the loading platform 70, the sample rack to be tested on the loading platform 70 is moved to the transport channel by the platform loading mechanism 71, and then the sample rack to be tested is first dispatched into the blood cell analyzer for routine blood testing, e.g., first routine blood testing, by the sample moving device. After the routine blood testing is completed, the sample moving device allocates and dispatches the sample rack to be tested according to the operating states of the multiple specific protein analyzers, e.g., preferentially dispatches into the idle specific protein analyzer. In some embodiments, when the specific protein analyzers of the sample analysis system are all in a busy state, the sample rack to be tested that has undergone routine blood testing can be temporarily stored in the feeding mechanism of the blood cell analyzer to wait, and then dispatched when the specific protein analyzer is idle.

[0077] Correspondingly, the measurement mode information identifier can be a normal Chinese character or English letter, etc. text identifier or string identifier, and in addition, the measurement mode information identifier can also be a bar code, a two-dimensional code, etc. pattern identifier with more information.

[0078] When the sample container passes through the scanning device, the scanning device can acquire the measurement mode information of the sample in the sample container on the sample rack to be tested, and then transmit the measurement mode information to the control device 30 through the blood cell analyzer.

[0079] In some embodiments of the present application, the scanning device of the blood cell analyzer can identify the sample rack and the sample bar code, and store the correspondence between the sample and its position on the sample rack. The specific protein analyzer can obtain the measurement mode of each sample on the sample rack by identifying the sample rack bar code, based on the correspondence between the sample and the sample rack established by the blood cell analyzer.

[0080] In the specific detection process, the control device 30 can control the sample transfer device to transfer the sample rack to be detected to the blood cell analyzer with the scanning device, to perform the first blood routine test, and to obtain the measurement mode information of each sample container on the sample rack to be detected. Then, when the control device 30 analyzes the measurement mode information and finds that the sample rack to be detected has a sample container that needs to be detected for specific protein, the control device 30 controls the sample transfer device to transfer the sample rack to be detected after the first blood routine test to the detection area of one of the at least two specific protein analyzers, according to the running state information.

[0081] In other embodiments, the scanning device can also be arranged independently of the blood cell analyzer, such as Figure 3 As shown in FIG. 1, the scanning device 101 can be arranged on the transmission mechanism 41 independently, and the position of the scanning device 101 is in front of the at least two specific protein analyzers in the transmission direction X, and as shown in FIG. 2, the scanning device 101 is directly connected to the control device 30. Figure 3

[0082] In other embodiments of the present application, the scanning device can also be arranged on the loading platform 70 to identify the sample rack and the sample bar code placed on the loading platform 70, and to establish and store the correspondence between the sample and its position on the sample rack. The blood cell analyzer and / or the specific protein analyzer can obtain the measurement mode of each sample on the sample rack by identifying the sample rack bar code, based on the correspondence between the sample and the sample rack established by the scanning device on the loading platform 70.

[0083] In other embodiments of the present application, the scanning device can also be arranged on the loading platform 70 to identify the sample rack and the sample bar code placed on the loading platform 70, and to establish and store the correspondence between the sample and its position on the sample rack. The blood cell analyzer and / or the specific protein analyzer can obtain the measurement mode of each sample on the sample rack by identifying the sample rack bar code, based on the correspondence between the sample and the sample rack established by the scanning device on the loading platform 70.

[0084] ​Since the blood routine test data is the basis for medical staff to judge the physical condition of the subject, and when a specific protein analyzer is a whole blood specific protein analyzer (e.g., a whole blood CRP analyzer) for detecting specific proteins using whole blood, the blood routine test data may be needed to correct the whole blood specific protein detection result, the blood routine test data needs to be as accurate as possible. In order to maximize the accuracy of the blood routine test data, in an embodiment of the present application, the control device 30 is electrically connected to each blood cell analyzer, and after the blood routine analysis of each blood cell analyzer, the blood routine test data is sent to the control device 30.

[0085] The control device 30 will analyze the received blood routine test data, and if it is determined that the blood routine test data of a certain sample is problematic, the control device 30 will also arrange for the blood routine retest of the sample.

[0086] In specific operation, the control device 30 can determine the sample container of the blood routine test data meeting the preset retest condition as a retest sample container, and determine a retest blood cell analyzer in at least one blood cell analyzer as a retest blood cell analyzer for the retest sample container.

[0087] After determining the retest blood cell analyzer, the control device 30 can move the retest sample container to the retest blood cell analyzer for blood routine retest.

[0088] In a specific application, if the to-be-tested sample rack contains both the retest sample container and the sample container that needs to be tested for specific proteins, the control device 30 can control the sample moving device to move the to-be-tested sample rack that has undergone the first blood routine test to the retest blood cell analyzer for blood routine retest, and then control the sample moving device to move the to-be-tested sample rack that has undergone the blood routine retest to the detection area of one of the at least two specific protein analyzers for specific protein detection.

[0089] This way of preferentially performing blood routine retest on the to-be-tested sample rack containing both the retest sample container and the sample container that needs to be tested for specific proteins, and then performing specific protein detection, can make the critical sample that needs to be retested complete the blood routine retest in priority, and timely issue the blood routine report on the basis of ensuring quality.

[0090] In the above application scenario, in some embodiments, all blood cell analyzers of the sample analysis system are located in front of the specific protein analyzers in the transmission direction along the transmission channel, as shown in FIG. 1. Figure 5 At this time, the retest sample container can be further ensured to be timely retested for blood routine, that is, the critical value can be ensured to be timely reported for blood routine report in the case of quality priority.

[0091] In another application, when the sample rack to be tested contains both the recheck sample container and the sample container requiring specific protein detection, the control device 30 can first move the sample rack to be tested after the first blood routine test to the detection area of one of the at least two specific protein analyzers for specific protein detection, and then move the sample rack to be tested after specific protein detection to the recheck blood cell analyzer for blood routine recheck. This priority of specific protein detection for the sample rack to be tested containing both the recheck sample container and the sample container requiring specific protein detection, and then blood routine recheck, can reduce the specific protein detection waiting time, issue the specific protein detection report as soon as possible, and not be affected by recheck, i.e., priority of specific protein detection efficiency.

[0092] In the above application scenarios, in some embodiments, the blood cell analyzers and specific protein analyzers of the sample analysis system are arranged alternately along the transmission direction of the transmission channel, as shown in FIG. 1. Figure 6 At this time, it can be further ensured that the samples on the sample rack to be tested are transported to the nearest specific protein for specific protein detection as soon as possible after the first blood routine test.

[0093] In some embodiments of the present application, at least two blood cell analyzers of the sample analysis system include at least one high-specification blood cell analyzer and at least one low-specification blood cell analyzer, and the detection items of the high-specification blood cell analyzer are different from, in particular more than and / or better than, the detection items of the low-specification blood cell analyzer. Here, the blood routine detection items, i.e., blood routine detection parameters, can include, for example, white blood cell detection (classification and / or counting), red blood cell detection (classification and / or counting), NRBC (nucleated red blood cell) detection, platelet impedance method detection, platelet optical method detection, reticulocyte detection, blast cell detection, malaria detection, etc. For example, the low-specification blood cell analyzer is configured to be able to perform only routine white blood cell detection (classification and / or counting) and red blood cell detection (classification and / or counting), and platelet impedance method detection, while the high-specification blood cell analyzer is configured to be able to perform white blood cell detection (classification and / or counting), red blood cell detection (classification and / or counting), NRBC detection, platelet impedance method detection, platelet optical method detection, reticulocyte detection, blast cell detection, and malaria detection. When performing blood routine recheck, in one case, the blood routine recheck can be performed by the blood cell analyzer for the first blood routine test, and in another case, the blood routine recheck can also be performed by a blood cell analyzer different from the blood cell analyzer for the first blood routine test.

[0094] Generally, if the detection items of the blood routine reexamination to be performed are the same as the detection items of the first blood routine examination, any hematology analyzer can be selected to perform the blood routine reexamination, preferably the hematology analyzer (the current hematology analyzer) used for the first blood routine examination is selected to perform the reexamination, i.e., preferably the local retest is selected. However, if the detection items of the blood routine reexamination to be performed are different from the detection items of the first blood routine examination, a hematology analyzer capable of achieving different detection items needs to be selected to perform the blood routine reexamination, which is generally a high-configuration hematology analyzer.

[0095] For example, the samples on the sample rack to be tested are first subjected to blood routine examination in the low-configuration hematology analyzer. If the control device 30 determines that some samples on the sample rack to be tested need to be subjected to blood routine reexamination with different detection items by analyzing the blood routine examination data of the low-configuration hematology analyzer, the control device 30 can control the sample moving device to move the sample rack to be tested to the high-configuration hematology analyzer so as to perform blood routine reexamination on the reexamination sample container.

[0096] In specific applications, considering the pipeline transmission efficiency of the sample rack to be tested in the transmission channel, the low-configuration hematology analyzer is located in front of the high-configuration hematology analyzer in the transmission direction along the transmission channel. In this way, the samples on the sample rack to be tested can be sequentially moved to the high-configuration hematology analyzer when blood routine reexamination with different detection items is needed, and after the blood routine reexamination, the samples can directly enter the specific protein analyzer located at the rear.

[0097] Therefore, in an embodiment of the present application, at least two reexamination modes can be used when the sample is subjected to blood routine reexamination, which can include the same item reexamination mode and the additional item reexamination mode. The same item reexamination mode refers to the detection items of the first blood routine examination and the blood routine reexamination being the same. The additional item reexamination mode refers to the detection items of the first blood routine examination being different from the detection items of the blood routine reexamination, for example, the blood routine reexamination needs to detect new detection items or needs to use different detection methods to retest the same detection items. In some embodiments, the same item reexamination mode can also be referred to as the original mode reexamination mode, and the additional item reexamination mode can also be referred to as the non-original mode reexamination mode.

[0098] In a specific application, the control device 30 is further configured to determine a review mode of the review sample container according to the blood routine test data, and when the sample rack to be tested includes a review sample container with a same-item review mode, the control device 30 controls the sample transfer device to transfer the sample rack to be tested to the hematology analyzer that performs the first blood routine test on the review sample container for review; and when the sample rack to be tested includes a review sample container with an additional-item review mode, the control device 30 controls the sample transfer device to transfer the sample rack to be tested to the high-configuration hematology analyzer for review. For example, when the platelet impedance method test result in the blood routine test data indicates that there is a platelet low value abnormality, the platelet needs to be reviewed by using the optical method to determine whether the result of the first blood routine test on the platelet low value abnormality is accurate.

[0099] Further, for the positional relationship between the hematology analyzers and the specific protein analyzers, the following setting can be performed:

[0100] At least one of the at least two specific protein analyzers is located between the low-configuration hematology analyzer and the high-configuration hematology analyzer.

[0101] In this way, for the control device, when the sample rack to be tested includes a review sample container with an additional-item review mode and a sample container that needs to be tested for specific protein, that is, when the same sample rack to be tested includes two sample containers that need to be tested by different tests, the control device controls the sample transfer device to first transfer the sample rack to be tested to the detection area of the specific protein analyzer located between the low-configuration hematology analyzer and the high-configuration hematology analyzer for specific protein testing on the sample that needs to be tested for specific protein; and then controls the sample transfer device to transfer the sample rack to be tested to the high-configuration hematology analyzer for review after the specific protein testing is completed.

[0102] This specific protein analyzer and hematology analyzer setting mode can be used as follows: when there are five sample containers in the sample rack to be tested, and after passing through the low-configuration hematology analyzer, the samples in two of the sample containers need to be tested for additional items, and the samples in the other three sample containers do not need to be tested for additional items, the samples that do not need to be tested for blood routine review can be preferentially tested for specific protein, and then the samples that need to be tested for blood routine review can be tested for blood routine review, so that the specific protein testing on the samples in the sample rack to be tested can be quickly performed, and the specific protein testing waiting time can be reduced.

[0103] The embodiments of the present application also provide a sample analysis system, which can include one specific protein analyzer for specific protein testing, a sample transfer device, a control device 30, and at least two hematology analyzers for blood routine testing. As described above, the control device 30 can be configured to determine a review mode of the review sample container according to the blood routine test data, and when the sample rack to be tested includes a review sample container with a same-item review mode, the control device 30 controls the sample transfer device to transfer the sample rack to be tested to the hematology analyzer that performs the first blood routine test on the review sample container for review; and when the sample rack to be tested includes a review sample container with an additional-item review mode, the control device 30 controls the sample transfer device to transfer the sample rack to be tested to the high-configuration hematology analyzer for review. Figure 7As shown, the figure includes: a first blood cell analyzer 61, a second blood cell analyzer 62, a specific protein analyzer 21 (which can be a CRP analyzer for detecting C-reactive protein).

[0104] The sample transfer device includes a transport mechanism 41 having a transport channel for transferring a sample rack in which a sample container is placed in the transport channel, and at least three feeding mechanisms 42 having detection channels, each feeding mechanism 42 being arranged at intervals along the transport direction of the transport channel, and the feeding mechanism 42 being capable of transferring the sample rack from the transport channel to the detection channel and from the detection channel to the transport channel. For the sample transfer device, please refer to the description in Embodiment 1, which will not be repeated here.

[0105] The specific protein analyzer 21 and each blood cell analyzer correspond to one feeding mechanism 42, and the detection regions of the specific protein analyzer 21, the first blood cell analyzer 61, and the second blood cell analyzer 62 correspond to the detection channels of the corresponding feeding mechanisms 42, respectively; and along the transport direction of the transport channel, the specific protein analyzer 21 is located between the first blood cell analyzer 61 and the second blood cell analyzer 62.

[0106] The control device 30 is electrically connected to the sample transfer device and is configured to obtain measurement mode information of the sample container on the sample rack to be tested, and control the sample transfer device to transfer the sample-loaded sample rack to be tested to one or more of the specific protein analyzer 21, the first blood cell analyzer 61, and the second blood cell analyzer 62 for corresponding detection.

[0107] The sample analysis system provided by the embodiments of the present application is arranged at intervals along the transport channel with at least two feeding mechanisms 42, and along the transport direction of the transport channel, one specific protein analyzer and at least two blood cell analyzers are arranged. For the sample rack to be tested, under the driving of the transport mechanism 41, the control device 30 can control the sample transfer device to transfer the sample-loaded sample rack to be tested to the specific protein analyzer or any one of the blood cell analyzers for corresponding detection, thereby reasonably allocating the sample rack and improving the detection efficiency of the sample.

[0108] Further, since the blood routine test data is the basis for medical staff to judge the physical condition of the subject, and when the specific protein analyzer is a whole blood specific protein analyzer for detecting specific proteins using whole blood, the blood routine test data may be needed to correct the whole blood specific protein detection result, so the blood routine test data needs to be as accurate as possible. In order to maximize the accuracy of the blood routine test data, in the embodiments of the present application, the control device 30 is electrically connected with each blood cell analyzer, and after the blood routine analysis of each blood cell analyzer, the blood routine test data is sent to the control device 30.

[0109] The control device 30 analyzes the received blood routine test data, and if it is determined that the blood routine test data of the sample in a certain sample container on the sample rack to be tested meets the preset recheck condition, the blood routine recheck of the sample is controlled.

[0110] In specific operation, the control device 30 can determine the sample container whose blood routine test data meets the preset recheck condition as a recheck sample container, and determine one of the at least two blood cell analyzers as a recheck blood cell analyzer for rechecking the recheck sample container. After determining the recheck blood cell analyzer, the control device 30 can move the recheck sample container to the recheck blood cell analyzer for blood routine recheck.

[0111] In specific application, if the sample rack to be tested contains both the recheck sample container and the sample container that needs to be detected for specific proteins, the control device 30 can control the sample moving device to move the sample rack to be tested that has undergone the first blood routine test to the recheck blood cell analyzer for blood routine recheck, and then control the sample moving device to move the sample rack to be tested that has undergone the blood routine recheck to the detection area of the specific protein analyzer for specific protein detection.

[0112] Such a sample rack to be tested containing both the recheck sample container and the sample container that needs to be detected for specific proteins is preferentially subjected to blood routine recheck, and then subjected to specific protein detection, which can make the critical sample that needs to be rechecked preferentially complete blood routine recheck, and timely issue a blood routine report on the basis of ensuring quality.

[0113] In another application, if the sample rack to be tested contains both the recheck sample container and the sample container that needs to be detected for specific proteins, the control device 30 can also move the sample rack to be tested that has undergone the first blood routine test to the detection area of the specific protein analyzer for specific protein detection, and then move the sample rack to be tested that has undergone the specific protein detection to the recheck blood cell analyzer for blood routine recheck.

[0114] The sample rack containing both the recheck sample container and the sample container for specific protein detection is given priority for specific protein detection, and then the blood routine recheck is performed, which can reduce the detection waiting time of specific protein, issue the specific protein detection report as soon as possible, and is not affected by recheck, that is, specific protein efficiency priority.

[0115] In the above application scenarios, in some embodiments, when the blood routine recheck is performed, in one case, the blood routine recheck can be performed by the hematology analyzer used for the first blood routine detection, and in another case, the blood routine recheck can also be performed by a hematology analyzer different from the hematology analyzer used for the first blood routine detection.

[0116] Generally, if the detection items of the blood routine recheck to be performed are the same as the detection items of the first blood routine detection, any hematology analyzer can be selected to perform the blood routine recheck, and it is preferred to select the hematology analyzer (the current hematology analyzer) used for the first blood routine detection to perform the recheck, that is, it is preferred to perform the local retest. However, if the detection items of the blood routine recheck to be performed are different from the detection items of the first blood routine detection, a hematology analyzer capable of achieving different detection items needs to be selected to perform the blood routine recheck, which is usually a high-spec hematology analyzer.

[0117] In some embodiments of the present application, the at least two hematology analyzers include at least one high-spec hematology analyzer and at least one low-spec hematology analyzer, and the detection items of the high-spec hematology analyzer are different from the detection items of the low-spec hematology analyzer.

[0118] Further, the samples on the sample rack to be tested are first subjected to blood routine detection in the low-spec hematology analyzer. If the control device 30 determines through analysis of the blood routine detection data of the low-spec hematology analyzer that some samples on the sample rack to be tested need to be subjected to blood routine recheck with different detection items, the control device 30 can control the sample moving device to move the sample rack to be tested to the high-spec hematology analyzer, so as to perform blood routine recheck on the recheck sample container.

[0119] In a specific application, in consideration of the pipeline transmission efficiency of the sample racks to be tested in the transmission channel, the specific protein analyzer is located behind the low blood cell analyzer and in front of the high blood cell analyzer in the transmission direction along the transmission channel. In this way, when the control device 30 includes a recheck sample container with a recheck mode of an added item recheck mode and a sample container that needs to be tested for specific proteins on a sample rack to be tested, that is, when there are two sample containers that need to be tested for different tests on the same sample rack to be tested, the control device 30 can control the sample transfer device to first transport the sample rack to be tested to the detection area corresponding to the specific protein analyzer between the low blood cell analyzer and the high blood cell analyzer to test the sample for specific proteins, and then control the sample transfer device to transport the sample rack to be tested to the high blood cell analyzer for recheck after the specific protein test is completed.

[0120] In some embodiments of the present application, other analyzers can be arranged along the transmission direction of the transmission channel of the transmission mechanism 41 on the basis of the low blood cell analyzer and the high blood cell analyzer, which are within the protection scope of the present application. Figure 7

[0121] In some embodiments of the present application, as shown in Figure 8 FIG. 6 is a structural schematic diagram of a control device provided in an embodiment of the present application. The control device 30 at least includes a processing component 31, a RAM 32, a ROM 33, a communication interface 34, a storage 36, and an I / O interface 35, wherein the processing component 31, the RAM 32, the ROM 33, the communication interface 34, the storage 36, and the I / O interface 35 communicate through a bus 37.

[0122] The processing component can be a CPU, a GPU, or other chips with computing ability.

[0123] The storage 36 stores various computer programs and data required for executing the computer programs for the processor component 31 to execute, such as an operating system and application programs. In addition, if necessary, data required to be stored locally during sample testing can be stored in the storage 36.

[0124] ​The I / O interface 35 is composed of a serial interface such as USB, IEEE 1394, or RS-232C, a parallel interface such as SCSI, IDE, or IEEE 1284, and an analog signal interface composed of a D / A converter and an A / D converter. An input device composed of a keyboard, a mouse, a touch panel, or other control buttons is connected to the I / O interface 35, and a user can directly input data to the control device 30 using the input device. In addition, a display having a display function, such as a liquid crystal panel, a touch panel, an LED display, or the like, can be connected to the I / O interface 35, and the control device 30 can output processed data as image display data to the display to display the data, such as analysis data, instrument operation parameters, or the like.

[0125] The communication interface 34 is an interface of any communication protocol known at present. The communication interface 34 communicates with the outside through a network. The control device 30 can transmit data between any device connected through the network using a certain communication protocol through the communication interface 34.

[0126] It should be noted that the relational terms herein such as first and second and the like can be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any such actual relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variations thereof, are intended to cover a non-exclusive inclusion such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element preceded by "comprises... a" does not, without more constraints, foreclose the existence of additional identical elements in the process, method, article, or apparatus that comprises the recited element.

[0127] Various features described in the various embodiments, drawings, and claims of the specification can be combined in any manner within the scope of the present application.

[0128] The above description is merely that of the specific embodiments of the present application, and enables those skilled in the art to understand or implement the present application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and generic principles defined herein can be applied to other embodiments without departing from the spirit or scope of the application. Thus, the present application is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A sample analysis system, characterized in that, include: The system includes at least two specific protein analyzers for specific protein detection, at least one hematology analyzer for routine blood tests, sample transfer equipment, and control equipment, wherein... The sample transfer device includes: a transfer mechanism with a transfer channel and at least three feeding mechanisms with detection channels. The transfer mechanism is used to transfer a sample rack containing a sample container in the transfer channel. Each feeding mechanism is spaced apart along the transfer direction of the transfer channel. The feeding mechanism can transfer the sample rack from the transfer channel to the detection channel and can also transfer the sample rack from the detection channel to the transfer channel. Each of the specific protein analyzers corresponds to one of the feeding mechanisms, and the detection area of ​​each specific protein analyzer corresponds to the detection channel of its corresponding feeding mechanism; each of the hematology analyzers corresponds to one of the feeding mechanisms, and the detection area of ​​each hematology analyzer corresponds to the detection channel of its corresponding feeding mechanism. The at least two specific protein analyzers are configured to detect at least one of the same specific proteins; Along the transmission direction of the transmission channel, at least one of the hematology analyzers is located in front of the at least two specific protein analyzers; The control device is electrically connected to each of the specific protein analyzers, each of the hematology analyzers, and the sample transfer device and is configured to: control the sample transfer device to transfer a sample rack containing at least one sample container to the detection area of ​​one of the hematology analyzers, so as to perform an initial routine blood test on the sample container on the sample rack and obtain the initial routine blood test data, and determine the sample container that needs to be retested based on the initial routine blood test data; In addition, the system acquires the operating status information of each of the specific protein analyzers and the measurement mode information of the sample containers on the sample rack to be tested. When the measurement mode information indicates that there are sample containers on the sample rack to be tested that need to be tested for specific proteins, the system controls the sample transfer device to transfer the sample rack to be tested after the first routine blood test to the detection area of ​​one of the at least two specific protein analyzers, so as to perform specific protein detection on the samples in the sample containers that need to be tested for specific proteins. Furthermore, when the sample rack to be tested simultaneously contains sample containers that require a repeat blood routine test and sample containers that require specific protein detection, the sample transfer device is controlled to first transfer the sample rack to be tested, which has undergone the first blood routine test, to the detection area of ​​one of at least two specific protein analyzers, so as to perform specific protein detection on the samples in the sample containers that require specific protein detection. Then, the sample transfer device is controlled to transfer the sample rack to be tested, which has undergone specific protein detection, to the detection area of ​​one of the blood cell analyzers, so as to perform a repeat blood routine test on the samples in the sample containers on the sample rack that require a repeat blood routine test.

2. The sample analysis system according to claim 1, characterized in that, The operating status information includes the detection load information for each specific protein analyzer; The step of controlling the sample transfer device to transfer the sample rack to be tested to the detection area of ​​one of the at least two specific protein analyzers according to the operating status information includes: controlling the sample transfer device to transfer the sample rack to be tested to the detection area of ​​the specific protein analyzer with a smaller detection load among the at least two specific protein analyzers according to the detection load information of each specific protein analyzer.

3. The sample analysis system according to claim 2, characterized in that, The control device is also used to: determine the waiting time of the sample rack to be tested based on the detection load information of each specific protein analyzer, and after the waiting time has elapsed, control the sample transfer device to transfer the sample rack to be tested to the detection area of ​​the specific protein analyzer with the smaller detection load among the at least two specific protein analyzers.

4. The sample analysis system according to claim 3, characterized in that, The sample analysis system further includes an unloading platform and other analyzers different from the at least two specific protein analyzers and the at least one hematology analyzer. The control device is also used to: when the waiting time is longer than a preset time, control the sample transfer device to transfer the sample rack to be tested to the unloading platform or the other analyzer.

5. The sample analysis system according to claim 1, characterized in that, The at least one hematology analyzer includes a scanning device for acquiring measurement mode information of the sample container on the sample rack to be tested; And / or, each of the at least two specific protein analyzers includes a scanning device for confirming the measurement mode information of the sample container on the sample rack to be tested.

6. The sample analysis system according to claim 5, characterized in that, The sample analysis system further includes a loading platform and a platform loading mechanism. The loading platform is located in front of the at least one hematology analyzer along the transmission direction of the transmission channel and is used to place the sample rack to be tested. The platform loading mechanism is used to transfer the sample rack on the loading platform to the transmission channel. The loading platform is equipped with a scanning device for identifying the sample rack and sample identification on the loading platform, and establishing and storing the correspondence between the sample identification and its position on the sample rack.

7. The sample analysis system according to claim 1, characterized in that, The sample analyzer system includes at least two hematology analyzers for routine blood tests; Along the transmission direction of the transmission channel, at least one of the at least two hematology analyzers is located in front of the at least two specific protein analyzers.

8. The sample analysis system according to claim 7, characterized in that, The at least two hematology analyzers include: at least one high-match hematology analyzer and at least one low-match hematology analyzer, wherein the detection items of the high-match hematology analyzer are different from those of the low-match hematology analyzer; Along the transmission direction of the transmission channel, the low-chromosome hematology analyzer is located in front of the high-chromosome hematology analyzer.

9. The sample analysis system according to claim 8, characterized in that, The step of determining the sample container that needs to be retested for blood routine tests based on the initial blood routine test data includes: The sample container whose initial blood routine test data meets the preset retest conditions is identified as the retest sample container, and the retest mode of the retest sample container is determined. The retest mode includes the same item retest mode and the additional item retest mode. When the sample rack to be tested includes a retest sample container with the same retest mode, the sample transfer device is controlled to transfer the sample rack to the blood cell analyzer that performs the first blood routine test on the retest sample container for retesting. When the sample rack to be tested includes a retest sample container in the retest mode of the additional retest mode, the sample transfer device is controlled to transfer the sample rack to the high-performance blood cell analyzer for retesting.

10. The sample analysis system according to any one of claims 1 to 9, characterized in that, The at least two specific protein analyzers are selected from C-reactive protein analyzers, serum amyloid A analyzers, procalcitonin analyzers, or other specific protein analyzers, or an integrated machine that includes the analysis of two or more of these specific proteins.

11. A sample analysis system, characterized in that, include: The system includes at least two specific protein analyzers for specific protein detection, at least one hematology analyzer for routine blood tests, sample transfer equipment, and control equipment, wherein... The sample transfer device includes: a transfer mechanism with a transfer channel and at least three feeding mechanisms with detection channels. The transfer mechanism is used to transfer a sample rack containing a sample container in the transfer channel. Each feeding mechanism is spaced apart along the transfer direction of the transfer channel. The feeding mechanism can transfer the sample rack from the transfer channel to the detection channel and can also transfer the sample rack from the detection channel to the transfer channel. Each of the specific protein analyzers corresponds to one of the feeding mechanisms, and the detection area of ​​each specific protein analyzer corresponds to the detection channel of its corresponding feeding mechanism; each of the hematology analyzers corresponds to one of the feeding mechanisms, and the detection area of ​​each hematology analyzer corresponds to the detection channel of its corresponding feeding mechanism. The at least two specific protein analyzers are configured to detect at least one of the same specific proteins; Along the transmission direction of the transmission channel, at least one of the hematology analyzers is located in front of the at least two specific protein analyzers; The control device is electrically connected to each of the specific protein analyzers, each of the hematology analyzers, and the sample transfer device and is configured to: control the sample transfer device to transfer a sample rack containing at least one sample container to the detection area of ​​one of the hematology analyzers, so as to perform a first routine blood test on the sample in the sample container on the sample rack; In addition, the system acquires the operating status information of each of the specific protein analyzers and the measurement mode information of the sample containers on the sample rack to be tested. When the measurement mode information indicates that there are sample containers on the sample rack to be tested that need to be tested for specific proteins, the system controls the sample transfer device to transfer the sample rack to be tested after the first routine blood test to the detection area of ​​one of the at least two specific protein analyzers, so as to perform specific protein detection on the samples in the sample containers that need to be tested for specific proteins. In addition, the blood routine test data and specific protein test data of the sample are obtained, and the specific protein test data of the sample are corrected using the blood routine test data of the sample.

12. The sample analysis system according to claim 11, characterized in that, The blood routine test data includes the initial blood routine test data and the blood routine retest data; The control device is further configured to: control the sample transfer device to transfer the sample rack containing at least one sample container to the detection area of ​​one of the blood cell analyzers, so as to perform the first routine blood test on the sample in the sample container on the sample rack and obtain the first routine blood test data of the sample, and determine the sample container that needs to be retested based on the first routine blood test data; The control sample transfer device transfers the sample rack to be tested after the first routine blood test to the detection area of ​​one of the blood cell analyzers, so as to perform a routine blood test on the sample container on the sample rack that needs to be retested and obtain the routine blood test data; The step of correcting the specific protein detection data of the sample using the blood routine test data of the sample includes: correcting the specific protein detection data of the sample using the initial blood routine test data and / or the blood routine retest data of the sample.

13. The sample analysis system according to claim 12, characterized in that, The sample analysis system includes at least two hematology analyzers for routine blood tests; along the transmission direction of the transmission channel, a first hematology analyzer, a first specific protein analyzer, a second hematology analyzer, and a second specific protein analyzer are arranged sequentially. The control device is used to: control the sample transfer device to transfer the sample rack containing at least one sample container to the detection area of ​​the first blood cell analyzer, so as to perform the first blood routine test on the sample in the sample container on the sample rack and obtain the first blood routine test data of the sample, and determine the sample container that needs to be retested based on the first blood routine test data; And, when the sample rack to be tested simultaneously contains sample containers requiring routine blood count retesting, sample containers not requiring routine blood count retesting, and sample containers requiring specific protein detection, the sample transfer device is controlled to transfer the sample rack to be tested, which has been detected by the first blood cell analyzer, to the detection area of ​​the first specific protein analyzer, so as to perform specific protein detection on the sample in the sample container that requires specific protein detection but does not require routine blood count retesting, and to correct the specific protein detection data of the sample using the initial routine blood count data of the sample; the sample transfer device is controlled to transfer... The sample rack to be tested, after being detected by the first specific protein analyzer, is transferred to the detection area of ​​the second hematology analyzer to perform a complete blood count (CBC) retest on the sample in the sample container that requires a CBC retest and to obtain the CBC retest data; the sample transfer device is controlled to transfer the sample rack to be tested, after being detected by the second hematology analyzer, to the detection area of ​​the second specific protein analyzer to perform a specific protein test on the sample in the sample container that requires a specific protein test and a CBC retest, and the CBC retest data of the sample is used to correct the specific protein test data of the sample.

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