Mud moxibustion preparation for adjuvant therapy of joint function of stroke rehabilitation patient and preparation method of mud moxibustion preparation

Abstract

The invention belongs to the technical field of biological medicines, and discloses a mud moxibustion preparation for adjuvant therapy of joint functions of stroke rehabilitation patients and a preparation method of the mud moxibustion preparation. The mud moxibustion preparation is a qi-tonifying and blood-activating formula with astragalus membranaceus and ligusticum wallichii as the core, the pathological core of a qi deficiency and blood stasis type stroke rehabilitation patient is precisely met, and rehabilitation requirements are met from the source. According to the preparation method of the mud moxibustion preparation for adjuvant therapy of the joint function of the stroke rehabilitation patient, the crushing granularity is accurately controlled through a process end, the redundant process is simplified, and high efficiency of industrial preparation is achieved. The matrix is selected from auxiliary materials meeting the medical-grade safety standard, no adverse reaction is caused by skin irritation tests, the formed product is stable in texture, and the product is not prone to falling off when attached to the curved surface of the joint. The finished product compulsively passes a microbial limit test (the total number of bacteria is less than or equal to 100cfu / g, and the total number of mould and saccharomycetes is less than or equal to 10cfu / g), completely conforms to the safety specification of medical auxiliary materials, and can meet the safety requirement of a patient for long-term use according to a treatment course.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of biological medicine, and particularly relates to a mud moxibustion preparation for auxiliary treatment of joint function of a stroke rehabilitation patient and a preparation method thereof. BACKGROUND

[0002] At present, products for improving the joint function of stroke rehabilitation patients on the market mainly include external physiotherapy patches, ordinary traditional Chinese medicine mud moxibustions and rehabilitation training auxiliary devices. Among them, the external physiotherapy patches mainly have the core effect of warming and relieving pain, and can only relieve the discomfort of the joint surface; the ordinary traditional Chinese medicine mud moxibustions contain traditional Chinese medicine ingredients, but the formula is mainly aimed at general joint pain, does not focus on the core pathogenesis of "qi deficiency and blood stasis" of the stroke rehabilitation patient, and the traditional Chinese medicine ingredients are simply mixed, the penetration efficiency of the effective ingredients is low, and it is difficult to act on the deep tissue of the joint to improve the flexion and extension function; the rehabilitation training auxiliary devices need to be guided by professional personnel, and cannot regulate from the pathogenesis, and can only improve the flexion and extension difficulty caused by the poor blood circulation of the joint due to qi deficiency and blood stasis.

[0003] Core defects of prior art: Insufficient pathogenesis targeting: the formula is not designed in combination with the pathological characteristics of the stroke rehabilitation patient with qi deficiency and blood stasis, and the joint function cannot be improved from the perspective of "tonifying qi and activating blood, dredging collaterals and relieving joints"; Poor penetration of effective ingredients: the traditional Chinese medicine ingredients are difficult to penetrate the skin and fascia around the joint, and cannot fully act on the lesion site to improve the flexion and extension difficulty; Single function: only surface pain can be relieved or external force is assisted, and the dual needs of "regulating pathogenesis and improving local joint function" cannot be met; High cost: the current similar traditional Chinese medicine mud moxibustion product for stroke rehabilitation is generally sold at about 150 yuan per 500g, and the stroke rehabilitation treatment cycle is long (usually 6-12 months), and the patient uses it for a long time, which greatly increases the medical cost, causes some patients to give up continuous treatment due to economic burden, and affects the rehabilitation effect. SUMMARY

[0004] To solve the above technical problems, the mud moxibustion preparation for the auxiliary treatment of joint function of stroke rehabilitation patients is provided, which is prepared from a core qi-supplementing and blood-activating formula of Huangqi and Chuanxiong, accurately matches the pathological core of qi deficiency and blood stasis type stroke rehabilitation patients, and matches the rehabilitation needs from the root; the process accurately controls the crushing particle size, simplifies the redundant process, specially adds a transdermal enhancer, which is verified to increase the skin penetration rate of core traditional Chinese medicine active ingredients such as Huangqi Jiaji and Chuanxiongine by 3-5 times, ensures that the effective components break through the skin barrier and reach the deep tissue of the joint, accurately act on the lesion site, and strengthen the joint flexion function improvement effect; the use of far infrared ceramic powder ensures the synergistic effect of warming; the finished mud moxibustion product has no adverse reactions in skin irritation test, has stable texture after forming, and is not easy to fall off on the joint curved surface.

[0005] To achieve the above purpose, the following technical solutions are adopted in the present application: The mud moxibustion preparation for the auxiliary treatment of joint function of stroke rehabilitation patients, wherein the stroke is qi deficiency and blood stasis type stroke; The preparation is mainly prepared from the following raw materials in mass fraction: Huangqi 10-30 parts, Chuanxiong 2.5-7.5 parts, Guizhi 2.5-7.5 parts, Ganjiang 2.5-7.5 parts, Honghua 7.5-22.5 parts, oily matrix carrier 106.5-319.5 parts, microcrystalline wax 50-150 parts, thermal agent 7.5-22.5 parts, skin penetration agent 4-12 parts, far infrared ceramic powder 25-75 parts and volcanic mud 31.5-94.5 parts; The oily matrix carrier is composed of beeswax, black plaster matrix and coconut oil; The black plaster matrix is soybean oil; The skin penetration agent is laurocapram; The thermal agent is vanillyl butyl ether.

[0006] Preferably, the stroke is qi deficiency and blood stasis type stroke; The above auxiliary treatment of joint function is auxiliary for joint flexion difficulty.

[0007] The preparation is mainly prepared from the following raw materials in mass fraction: Huangqi 15-25 parts, Chuanxiong 3.5-6.5 parts, Guizhi 3.5-6.5 parts, Ganjiang 3.5-6.5 parts, Honghua 10.5-19.5 parts, oily matrix carrier 149-277 parts, microcrystalline wax 75-125 parts, thermal agent 10.5-19.5 parts, skin penetration agent 5.5-10.5 parts, far infrared ceramic powder 35-65 parts and volcanic mud 44-82 parts.

[0008] As preferably, the stroke is of qi deficiency and blood stasis type; The preparation is mainly prepared from the following raw materials in mass fraction: Radix Astragali 20 parts, Chuanxiong 5 parts, Cassia twig 5 parts, dried ginger 5 parts, safflower 15 parts, oily matrix carrier 213 parts, microcrystalline wax 100 parts, thermal agent 15 parts, skin penetration agent 8 parts, far infrared ceramic powder 50 parts and volcanic clay 64 parts.

[0009] As preferably, the oily matrix carrier is prepared from beeswax, microcrystalline wax, black plaster matrix and coconut oil in a weight ratio of 75:100:75:64.

[0010] A preparation method of a mud moxibustion preparation for assisting the treatment of joint function of stroke rehabilitation patients, comprising the following steps: S1, raw material pretreatment: According to the corresponding mass fraction, radix astragali, chuanxiong, cassia twig, dried ginger and safflower are selected, crushed and sieved, and impurities are removed to obtain radix astragali powder, chuanxiong powder, cassia twig powder, dried ginger powder and safflower powder, which are mixed to obtain traditional Chinese medicine powder for use; Select far infrared ceramic powder and volcanic clay, crush and sieve, and reserve for use; S2, oily matrix carrier preparation: According to the corresponding mass ratio, beeswax, black plaster matrix and coconut oil are selected, mixed in a container, heated and stirred until the beeswax is completely melted, and a uniform and transparent oily matrix carrier liquid is formed, which is kept warm for standby; S3, component mixing: In the oil matrix carrier liquid, first add the thermal agent and stir until it is completely dissolved, then add laurazepam and continue to stir evenly, then cool to the set temperature, stir while adding the traditional Chinese medicine powder, and finally add the far infrared ceramic powder and volcanic clay and continue to stir until the whole system is a fine mud initial product; S4, product preparation: Maintain the temperature of the initial product mud system, add microcrystalline wax and stir until the microcrystalline wax is completely melted and fully integrated with the initial product mud system; Then, when the system temperature decreases, the finished product mud is placed in a plastic mud moxibustion box that meets the safety standards, and naturally cooled to room temperature to obtain the mud moxibustion preparation product.

[0011] As preferably, in S1, the radix astragali, chuanxiong, cassia twig, dried ginger and safflower are crushed and sieved through a 200 mesh ordinary vibrating screen; The far infrared ceramic powder and volcanic clay are crushed and sieved through a 300-500 mesh screen.

[0012] As preferably, in the S2, the beeswax, the black plaster base and the coconut oil are mixed in a container and heated to 70-75 DEG C, and stirred for 8-10 min until the beeswax is completely melted; the temperature during the heat preservation is 65-70 DEG C.

[0013] As preferably, in the S3, the heat sensing agent is first added into the oily base carrier liquid with a heat preservation temperature of 60-65 DEG C, and stirred for 3-5 min until completely dissolved, and then the laurazepam is added and continuously stirred for 5-8 min until uniform; The set temperature is 55-60 DEG C; The stirring time for adding the traditional Chinese medicine powder is 15-20 min; The continuous stirring time for adding the far infrared ceramic powder and the volcanic clay is 20-25 min.

[0014] As preferably, in the S4, the temperature of the initial product mud system is 50-55 DEG C; The stirring time for adding the microcrystalline wax is 8-10 min; When the temperature is reduced to 45-50 DEG C, the finished product mud is placed in a packaging mold; The room temperature is 25-27 DEG C.

[0015] As preferably, the mud moxibustion preparation product has no cracking, no delamination, smooth surface, a pH value of 6.5-7.5, a total number of microbial bacteria of ≤100 cfu / g, and a total number of mold and yeast of ≤10 cfu / g.

[0016] Compared with the prior art, the present application has at least the following technical effects: The present application provides a mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, which has the following advantages: (1) The prescription compatibility is accurately matched with the pathogenesis, and the curative effect is improved: The mud moxibustion preparation is a "Huangqi+Chuanxiong" core tonifying qi and activating blood prescription, which accurately matches the pathological core of qi deficiency and blood stasis type of stroke rehabilitation patients, and matches the rehabilitation needs from the root. At the same time, through cost optimization: the high cost performance raw materials such as traditional Chinese medicine uniform goods and domestic first-class base are selected.

[0017] In the preparation method of the mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, the crushing particle size is accurately controlled through the process, the redundant process is simplified, and the efficiency of industrialized preparation is realized.

[0018] (II) In the preparation process of the mud moxibustion preparation, a transdermal enhancer is specially added, which has been verified to increase the skin penetration rate of core traditional Chinese medicine active ingredients such as astragaloside and ligustrazine by 3-5 times, ensuring that the effective components break through the skin barrier and reach the deep tissues of the joint, accurately acting on the lesion site, and strengthening the improvement effect of joint flexion and extension function; the far-infrared ceramic powder can stably release far-infrared rays after heating, assisting in increasing the local temperature of the joint to the physiotherapy golden interval of 38-42℃, accelerating the local blood circulation, and creating an optimal environment for the absorption of traditional Chinese medicine ingredients. A single application can maintain a 30-minute continuous warming effect without the need for repeated heating operations, which is suitable for the patient's home rehabilitation scene and improves the convenience of use.

[0019] (III) The mud moxibustion product is made of auxiliary materials that meet the medical grade safety standards, and has no adverse reactions after skin irritation test. The texture is stable after molding, and it is not easy to fall off when adhering to the joint surface. The product is forced to pass the microbial limit test (total bacterial count ≤100 cfu / g, total mold and yeast count ≤10 cfu / g), fully meeting the safety specifications of medical auxiliary materials, and meeting the safety needs of patients using it for a long time according to the treatment course.

[0020] (IV) The mud moxibustion preparation product is based on the formula design of "efficacy-cost" balance: under the premise of ensuring the core efficacy of "tonifying qi, activating blood, dredging collaterals and relieving joints", through traditional Chinese medicine grade optimization (common goods replacing special grade), auxiliary material domestic selection (domestic loperamide replacing imported), and packaging simplification, the limitations of "high efficacy means high cost" of existing products are broken through, and the balance between low cost and high efficacy is achieved; transdermal-heat synergistic mechanism is retained: although the cost is controlled, the synergistic combination of loperamide and far-infrared ceramic powder is retained to ensure the penetration of effective components and the warming and dredging of collaterals, avoiding the reduction of efficacy due to cost reduction, and solving the pain point of "insufficient efficacy" of existing low-cost products.

[0021] The practical packaging is used instead of high-end gift boxes on the packaging end of the product, and the cost of 500g of mud moxibustion per box is finally locked at 50-60 yuan, which is only 1 / 3-2 / 5 of the price of similar products on the market. The economic burden of long-term treatment of patients is greatly reduced, and the treatment compliance is significantly improved. DETAILED DESCRIPTION

[0022] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the present application will be briefly introduced in combination with the description of the embodiments or the prior art. Obviously, the following description of the technical contents is only some embodiments of the present application. It should be noted that the description of these embodiments is used to help understand the present application, but does not constitute a limitation on the present application.

[0023] The technical solutions of one specific embodiment of the present application are as follows: A mud moxibustion preparation for assisting the treatment of joint function of stroke rehabilitation patients, which is prepared from raw materials in mass fractions as follows: Radix Astragali, Chuanxiong, Ramulus Cinnamomi, Dried Ginger, Safflower, oily base carrier, microcrystalline wax, thermal agent, skin penetration agent, far infrared ceramic powder and volcanic clay.

[0024] The oily base carrier is composed of beeswax, black plaster base and coconut oil; The black plaster base is soybean oil; The skin penetration agent is laurocapram; The thermal agent is vanillyl butyl ether.

[0025]

[0026] A preparation method of a mud moxibustion preparation for assisting the treatment of joint function of stroke rehabilitation patients, comprising the following steps: 1. Raw material pretreatment Radix Astragali, Chuanxiong, Ramulus Cinnamomi, Dried Ginger and Safflower are respectively crushed, passed through a 200-mesh ordinary vibrating screen, and impurities are removed to obtain traditional Chinese medicine fine powder for standby.

[0027] The far infrared ceramic powder and the volcanic clay are passed through a 300-mesh screen to ensure uniform particle size and reduce the subsequent particle feeling, for standby.

[0028] 2. Oily base mixing (preferably integrate oily components to avoid repeated heating) A stainless steel container is taken, beeswax, refined soybean oil (black plaster base) and refined coconut oil are added, heated to 70-75℃, and stirred with an ordinary electric mixer for 8-10 minutes until the beeswax is completely melted to form a uniform transparent oily mixed base liquid, and the temperature is kept at 65-70℃ for standby.

[0029] 3. Functional component integration (add powder in stages to ensure uniform dispersion) The temperature of the oily mixed base liquid is kept at 60-65℃, vanillyl butyl ether (thermal agent) is added first, stirred for 3 minutes until completely dissolved, and then laurocapram (skin penetration agent) is added, and continues to stir for 5 minutes to ensure uniform dispersion of functional liquid components.

[0030] The temperature is reduced to 55-60℃, the traditional Chinese medicine fine powder is slowly added, and stirred for 15 minutes to avoid clumping of the powder; then the volcanic clay and the far infrared ceramic powder are added, and continue to stir for 20 minutes until the system is fine and there are no obvious particles or clumps.

[0031] 4. Microcrystalline wax melting and blending (add wax at the end to prevent burning, and accurately control temperature to ensure quality) Maintain the system temperature 50~55℃, add microcrystalline wax (melting point 48℃), low-speed stirring with an electric mixer for 8~10 minutes until the microcrystalline wax is completely melted and fully integrated with the mud system, and the temperature is continuously controlled during the process to avoid exceeding 60℃ to prevent the ingredients from deteriorating or burning due to high temperature.

[0032] 5. Molding and testing (simplified packaging, adapting to practical containers) When the temperature of the mixed system drops to 45~50℃, quickly pour it into a plastic mud moxibustion box that meets safety standards (instead of a round mold, directly molding to reduce the demolding step), and naturally cool to room temperature (about 25℃) to form a fixed shape of mud moxibustion products.

[0033] Product testing: focus on appearance (no cracking, no delamination, smooth surface), pH value (6.5-7.5), microbial limit (total bacterial count ≤100 cfu / g, total mold and yeast count ≤10 cfu / g); after passing, directly cover the plastic box cover, and cover with a simple sealing film (instead of aluminum-plastic packaging and high-end gift boxes) to further reduce packaging costs.

[0034] Example 1: A mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, the preparation is prepared from the following mass fractions of raw materials: Radix Astragali 10g, Chuanxiong 2.5g, Cassia Bark 2.5g, Dried Ginger 2.5g, Safflower 7.5g, oily matrix carrier 106.5g, microcrystalline wax 50g, thermal agent 7.5g, skin penetration agent 4g, far infrared ceramic powder 25g and volcanic clay 31.5g.

[0035] The stroke is a stroke of qi deficiency and blood stasis.

[0036] The oily matrix carrier is prepared from beeswax, black plaster matrix and coconut oil in a weight ratio of 75:100:75:63; The black plaster matrix is soybean oil.

[0037] The skin penetration agent is laurocapram; The thermal agent is vanillyl butyl ether.

[0038] The preparation method is the same as the specific embodiment.

[0039] Example 2: A mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, the preparation is prepared from the following mass fractions of raw materials: Radix Astragali 30g, Rhizoma Chuanxiong 7.5g, Ramulus Cinnamomi 7.5g, Rhizoma Zingiberis 7.5g, Flos Carthami 22.5g, oil base carrier 319.5g, microcrystalline wax 150g, thermal agent 22.5g, skin penetration agent 12g, far infrared ceramic powder 75g and volcanic clay 94.5g.

[0040] The stroke is a stroke of qi deficiency and blood stasis.

[0041] The oil base carrier is prepared from beeswax, black plaster base and coconut oil in a weight ratio of 75:100:75:63; The black plaster base is soybean oil.

[0042] The skin penetration agent is laurocapram; The thermal agent is vanillyl butyl ether.

[0043] The preparation method is the same as the specific embodiment.

[0044] Example 3: A mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, which is prepared from the following raw materials in mass fraction: Radix Astragali 15g, Rhizoma Chuanxiong 3.5g, Ramulus Cinnamomi 3.5g, Rhizoma Zingiberis 3.5g, Flos Carthami 10.5g, oil base carrier 149g, microcrystalline wax 75g, thermal agent 10.5g, skin penetration agent 5.5g, far infrared ceramic powder 35g and volcanic clay 44g.

[0045] The stroke is a stroke of qi deficiency and blood stasis.

[0046] The oil base carrier is prepared from beeswax, black plaster base and coconut oil in a weight ratio of 75:100:75:63; The black plaster base is soybean oil.

[0047] The skin penetration agent is laurocapram; The thermal agent is vanillyl butyl ether.

[0048] The preparation method is the same as the specific embodiment.

[0049] Example 4: A mud moxibustion preparation for auxiliary treatment of joint function of stroke rehabilitation patients, which is prepared from the following raw materials in mass fraction: Radix Astragali 25g, Rhizoma Chuanxiong 5g, Ramulus Cinnamomi 6.5g, Rhizoma Zingiberis 6.5g, Flos Carthami 19.5g, oil base carrier 77g, microcrystalline wax 125g, thermal agent 19.5g, skin penetration agent 10.5g, far infrared ceramic powder 65g and volcanic clay 82g.

[0050] The stroke is a stroke of qi deficiency and blood stasis.

[0051] The oily base carrier is prepared from beeswax, black plaster base and coconut oil in a weight ratio of 75:100:75:63; The black plaster base is soybean oil.

[0052] The epidermal penetration agent is laurocapram; The heat agent is vanillyl butyl ether.

[0053] The preparation method is the same as the specific embodiment.

[0054] Example 5: A mud moxibustion preparation for assisting the treatment of joint function of stroke rehabilitation patients, which is prepared from the following raw materials in mass fraction: Radix Astragali 20g, Chuanxiong 5g, Cassia Twig 5g, Dried Ginger 5g, Safflower 15g, oily base carrier 313g, heat agent 15g, epidermal penetration agent 58g and volcanic mud 64g; The stroke is of the type of qi deficiency and blood stasis.

[0055] The oily base carrier is prepared from beeswax, black plaster base and coconut oil in a weight ratio of 75:100:75:63; The black plaster base is soybean oil.

[0056] The epidermal penetration agent is laurocapram; The heat agent is vanillyl butyl ether.

[0057] The preparation method is the same as the specific embodiment.

[0058] Verification: 1. Cost accounting table: cost details of 500g mud moxibustion raw materials per box (unit: yuan): Traditional Chinese medicine components (20x0.058+5x0.042+5x0.018+5x0.072+15x0.144=3.98); Base components (75x0.02199+100x0.03055+75x0.035+63x0.03095+15x0.3371+8x0.09+63x0.0116+50x0.027=16.68 (yuan), total raw material cost 20.66 yuan; Plus production energy consumption, packaging, labor, the total cost is controlled in 50-60 yuan / box, compared with the existing product 150 yuan / box, the cost is reduced by 60%-67%; 2、Effective component detection report: through high performance liquid chromatography (HPLC) detection, the content of astragaloside in the mud moxibustion is ≥0.15mg / g, and the content of ligustrazine is ≥0.08mg / g, compared with the existing high-priced product (astragaloside ≥0.12mg / g, ligustrazine ≥0.06mg / g), the content of effective component is higher; 3、Patient use feedback: 10 cases of qi deficiency and blood stasis type stroke rehabilitation patients (monthly medical expenditure ≤800 yuan) were selected, after using the mud moxibustion for 4 weeks, the joint flexion angle of 8 patients was improved by 15-30℃, and all of them expressed that "the price is acceptable and can adhere to use", and no one interrupted the treatment due to cost problem, and there was no adverse reaction in the process of mud moxibustion.

[0059] Finally, it should be pointed out that: the above only for the preferred embodiments of the present application, and is not used to limit the protection scope of the present application. Any modification, equivalent replacement, improvement, etc. within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients, characterized in that, The stroke described is a type of stroke caused by qi deficiency and blood stasis. The formulation is mainly prepared from the following raw materials in parts by weight: Astragalus membranaceus 10-30 parts, Ligusticum chuanxiong 2.5-7.5 parts, Cinnamomum cassia 2.5-7.5 parts, Zingiber officinale 2.5-7.5 parts, Carthamus tinctorius 7.5-22.5 parts, oily matrix carrier 106.5-319.5 parts, microcrystalline wax 50-150 parts, thermosensitive agent 7.5-22.5 parts, epidermal penetrant 4-12 parts, far-infrared ceramic powder 25-75 parts, and volcanic mud 31.5-94.5 parts; The oily matrix carrier is composed of beeswax, black plaster matrix and coconut oil; The black plaster base is soybean oil; The epidermal penetrant is laurocapram; The heat-sensitive agent is vanillyl butyl ether.

2. The mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 1, characterized in that, The stroke described is a type of stroke caused by qi deficiency and blood stasis. The formulation is mainly prepared from the following raw materials in parts by weight: Astragalus membranaceus 15-25 parts, Ligusticum chuanxiong 3.5-6.5 parts, Cinnamomum cassia 3.5-6.5 parts, Zingiber officinale 3.5-6.5 parts, Carthamus tinctorius 10.5-19.5 parts, oily matrix carrier 149-277 parts, microcrystalline wax 75-125 parts, thermosensitive agent 10.5-19.5 parts, epidermal penetrant 5.5-10.5 parts, far-infrared ceramic powder 35-65 parts, and volcanic mud 44-82 parts.

3. The mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 2, characterized in that, The stroke described is a type of stroke caused by qi deficiency and blood stasis. The formulation is mainly prepared from the following raw materials in parts by weight: Astragalus membranaceus 20 parts, Ligusticum chuanxiong 5 parts, Cinnamomum cassia 5 parts, Zingiber officinale 5 parts, Carthamus tinctorius 15 parts, oily matrix carrier 213 parts, microcrystalline wax 100 parts, thermal agent 15 parts, epidermal penetrant 8 parts, far-infrared ceramic powder 50 parts and volcanic mud 64 parts.

4. A mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to any one of claims 1 to 3, characterized in that, The oily matrix carrier is prepared from beeswax, microcrystalline wax, black plaster matrix and coconut oil in a weight ratio of 75:100:75:

64.

5. A method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients as described in any one of claims 1 to 3, characterized in that, Includes the following steps: S1. Raw material pretreatment: According to the corresponding mass proportions, Astragalus membranaceus, Ligusticum chuanxiong, Cinnamomum cassia, Zingiber officinale and Carthamus tinctorius were selected, pulverized and sieved to remove impurities, and then the Astragalus membranaceus powder, Ligusticum chuanxiong powder, Cinnamomum cassia powder, Zingiber officinale powder and Carthamus tinctorius powder were mixed to obtain Chinese medicine powder for later use; Select far-infrared ceramic powder and volcanic mud, crush and sieve them separately, and set aside for later use; S2. Preparation of oil-based matrix carrier: Select beeswax, black plaster base and coconut oil according to the corresponding mass ratio, mix them in a container, heat and stir until the beeswax is completely melted to form a uniform and transparent oily base carrier liquid, keep it warm for later use; S3, Component Mixing: First, add the heat-sensing agent to the heat-insulating oily matrix carrier liquid and stir until completely dissolved. Then, add laurocapram and continue stirring until uniform. Then, cool down to the set temperature and add the Chinese medicine powder while stirring. Finally, add the far-infrared ceramic powder and volcanic mud and continue stirring until the whole system becomes a fine mud-like initial mud. S4. Finished Product Preparation: Maintain the temperature of the initial clay system, add microcrystalline wax and stir until the microcrystalline wax is completely melted and fully integrated with the initial clay system; Then, wait for the system temperature to drop and place the finished mud in a plastic mud moxibustion box that meets safety standards, and let it cool naturally to room temperature to obtain the finished mud moxibustion preparation.

6. The method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 5, characterized in that, In S1, Astragalus membranaceus, Ligusticum chuanxiong, Cinnamomum cassia, Zingiber officinale and Carthamus tinctorius are pulverized and passed through a 200-mesh ordinary vibrating sieve; The far-infrared ceramic powder and volcanic mud are pulverized and then passed through a 300-500 mesh sieve.

7. The method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 5, characterized in that, In step S2, beeswax, black plaster base and coconut oil are mixed and placed in a container and heated to 70~75℃, and stirred for 8~10 minutes until the beeswax is completely melted; the temperature during heat preservation is 65~70℃.

8. The method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 5, characterized in that, In step S3, a heat-sensitive agent is first added to an oily matrix carrier liquid at a heat preservation temperature of 60-65°C and stirred for 3-5 minutes until completely dissolved. Then, laurocapram is added and stirred for another 5-8 minutes until homogeneous. The set temperature is 55~60℃; The stirring time for adding the Chinese herbal medicine powder is 15-20 minutes; The addition of far-infrared ceramic powder and volcanic mud, followed by continuous stirring, lasts for 20-25 minutes.

9. The method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 5, characterized in that, In S4, the temperature of the initial mud system is 50~55℃; The stirring time for adding microcrystalline wax is 8-10 minutes. Once the temperature drops to 45-50°C, place the finished mud into a packaging mold; The room temperature is 25~27℃.

10. A method for preparing a mud moxibustion preparation for adjuvant treatment of joint function in stroke rehabilitation patients according to claim 5, characterized in that, The finished mud moxibustion preparation has a smooth surface without cracks or delamination, a pH value of 6.5~7.5, a total bacterial count of ≤100cfu / g, and a total mold and yeast count of ≤10cfu / g.

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