Atorvastatin calcium intermediate M4 tablet drying equipment

Abstract

The invention relates to the technical field of medicine production, in particular to atorvastatin calcium intermediate M4 tablet drying equipment which comprises a box body, a vibration drying assembly, an electric control transmission roller, interception cloth and the like. The box body is provided with a vibration drying assembly used for drying tablets in a vibration mode. A plurality of electric control transmission rollers are arranged on the box body; every two electric control transmission rollers which are opposite front and back are jointly and rotationally connected with intercepting cloth for intercepting and collecting medicine powder; the intercepting cloth is in an end-to-end ring shape; a plurality of collecting cavities are formed in the box body; the side, away from the box body, of each piece of intercepting cloth is located in the corresponding collecting cavity. The medicine powder is intercepted through the intercepting cloth, the situation that water and gas are mixed with the medicine powder and adhere to the interior of the exhaust pipe is prevented, waste of the medicine powder is avoided, and meanwhile the follow-up equipment cleaning workload is relieved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medicine production, and particularly relates to an atorvastatin calcium intermediate M4 tablet drying equipment. BACKGROUND

[0002] Atorvastatin calcium is a commonly used lipid-lowering drug, which is prepared and synthesized based on atorvastatin calcium intermediate M4 and belongs to statins. Atorvastatin calcium is mainly used for treating hypercholesterolemia and preventing cardiovascular diseases. In the production process of atorvastatin calcium, atorvastatin calcium needs to be dried.

[0003] When the atorvastatin tablets are dried, a fluidized bed dryer is usually used to dry the tablets. The fluidized bed dryer mainly makes the tablets vibrate and transmit, and uses hot air to dry the tablets in the transmission process. When the tablets are vibrated and transmitted, the tablets are abraded by each other, and the tablets are abraded by the vibrating laying plate, so that the active ingredients and auxiliary materials on the surface of the tablets form fine powder. Although the existing fluidized bed dryer has a powder suction and recovery mechanism, when the hot air dries the tablets, the water vapor evaporated from the tablets is sucked away together with the powder by the powder suction and recovery mechanism. Due to the presence of water vapor, the water vapor and the powder are adhered to the inner wall of the suction pipeline, which not only reduces the recovery effect of the powder, causes waste of the powder, but also increases the workload of subsequent equipment cleaning.

[0004] Further, in the process of vibrating and transmitting the tablets, the tablets collide with the laying plate, and the tablets are easily broken. The small particle tablets after breaking pass through the air holes of the laying plate in the vibration process and fall to the bottom of the box and are continuously baked by the hot air, so that the small particle tablets are over-dried, which causes the degradation of the active ingredients of the small particle tablets, and the drug effect of the small particle tablets recovered subsequently is reduced. SUMMARY

[0005] In order to overcome the shortcomings that the water vapor evaporated from the tablets is adhered to the inner wall of the suction pipeline when the existing fluidized bed dryer dries the tablets, which causes waste of the powder and increases the workload of subsequent equipment cleaning, the present application provides an atorvastatin calcium intermediate M4 tablet drying equipment.

[0006] The technical implementation scheme of the application is: an atorvastatin calcium intermediate M4 tablet drying equipment, comprising a box; the box is provided with an inlet; the box is provided with an outlet; further comprising a vibrating drying assembly, an electric control driving roller, an interception cloth, a flow guide assembly and a scraper; the box is provided with a vibrating drying assembly for vibrating and drying tablets; the box is provided with a plurality of electric control driving rollers; each of the two electric control driving rollers opposite to each other is jointly rotatably connected with an interception cloth for intercepting and collecting powder; the interception cloth is annular with the head connected to the tail; a plurality of collection cavities are formed in the box; each of the interception cloths is located in the corresponding collection cavity on the side away from the box; the box is provided with a flow guide assembly for guiding hot air flow to improve drying effect; each of the collection cavities is connected with a scraper for scraping the powder on the interception cloth; each of the scrapers is provided in an inclined state with the front higher and the rear lower.

[0007] More preferably, the vibrating drying assembly comprises an air inlet pipe, an air outlet pipe, a laying plate and a vibrating motor; a plurality of air inlet pipes for supplying hot air flow are fixedly connected and communicated to the lower part of the box; a plurality of air outlet pipes are fixedly connected and communicated to the upper side of the box; the suction port of each air outlet pipe is located in the inner ring area of the corresponding interception cloth; a laying plate for carrying tablets is fixedly connected in the box; a plurality of air holes are formed in the laying plate; a plurality of vibrating motors are fixedly connected to the box.

[0008] More preferably, the flow guide assembly comprises a guide plate, a baffle and a flow guide plate; a plurality of guide plates for guiding hot air flow are fixedly connected in the box; all the guide plates jointly form an eight-shaped structure; a baffle for guiding tablet particles is fixedly connected in the box; the baffle is located above all the guide plates; a plurality of receiving cavities are formed in the box; each of the receiving cavities is in communication with the space above the guide plates in the box; a flow guide plate for guiding hot air flow is fixedly connected in the box; the flow guide plate is located above the laying plate; the flow guide plate is made of rubber.

[0009] More preferably, it further comprises rubber hammers; a plurality of rubber hammers for knocking and vibrating the flow guide plate are rotatably connected to the upper side of the flow guide plate.

[0010] More preferably, it further comprises air blowing pipes; air blowing pipes for cleaning the powder on the interception cloth are fixedly connected and communicated to the upper side of the box; each of the air blowing pipes is located in the inner ring area of the corresponding interception cloth and is attached to the side of the interception cloth facing the collection cavity.

[0011] More preferably, it further comprises partitions; a plurality of partitions for blocking the suction air flow of the air outlet pipes are fixedly connected in the box; the partitions are located in the inner ring area of the corresponding interception cloth; the partitions are used to separate the air outlet pipes and the air blowing pipes.

[0012] More preferably, the bottom of the collection cavity is gradually lowered from front to rear.

[0013] More preferably, a heat insulation plate is arranged on each of the collecting cavity and the receiving cavity towards one side of the middle part of the box.

[0014] More preferably, the device further comprises a plurality of conducting plates, the upper side of the paving plate is fixedly connected with the plurality of conducting plates for conducting the knocking force, and each of the conducting plates is fixedly connected with the lower side of the flow guide plate.

[0015] More preferably, each of the two conducting plates opposite to each other is located on the same horizontal line as the corresponding rubber hammer.

[0016] Beneficial effects: the device realizes interception of the medicine powder through the interception cloth, prevents water vapor from being mixed with the medicine powder and adhering to the air exhaust pipe, avoids waste of the medicine powder, and reduces the workload of subsequent cleaning of the equipment; The medicine powder adhering to the interception cloth is blown off to the collecting cavity through the blowing pipe, so that the medicine powder is separated from the interception cloth for collection, the medicine powder is prevented from being dried for a long time on the interception cloth, degradation of active ingredients of the medicine is avoided, and the medicinal effect of the recycled medicine powder is avoided from being reduced; The air exhaust pipe and the collecting cavity are separated by the partition plate, so that the suction force of the air exhaust pipe is prevented from acting on the collecting cavity through the interception cloth, the medicine powder collected in the collecting cavity is prevented from being sucked and adhered to the interception cloth by the air exhaust pipe again, and the collection effect of the medicine powder in the collecting cavity is ensured; The small particle medicine tablets are transmitted to the receiving cavity for collection through the guide plate, so that the small particle medicine tablets are prevented from falling to the bottom of the box and being continuously baked by the hot air, the small particle medicine tablets are prevented from being excessively dried, the active ingredients of the recycled small particle medicine tablets are improved, and the medicinal effect of the recycled small particle medicine tablets is improved. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 It is a three-dimensional structure schematic diagram of an atorvastatin calcium intermediate M4 tablet drying device of the present application; Figure 2 It is a three-dimensional structure schematic diagram of an electric control transmission roller, an interception cloth, a vibrating drying assembly and a flow guide assembly combination of the present application; Figure 3 It is a three-dimensional structure schematic diagram of an interception cloth, a scraping piece, a flow guide assembly, a blowing pipe and a partition plate combination of the present application; Figure 4 It is a three-dimensional structure schematic diagram of a box, a vibrating drying assembly, a flow guide assembly and a conducting plate combination of the present application; Figure 5 It is a side view of a box, an interception cloth, a scraping piece, a vibrating drying assembly, a flow guide assembly and a conducting plate combination of the present application; Figure 6 It is a drying gas flow direction diagram of the present application.

[0018] The above-mentioned attached drawings include the following reference numerals: 1-box body, 1001-feed inlet, 1002-discharge outlet, 1003-collection chamber, 1004-storage chamber, 2-electrically controlled transmission roller, 3-intercepting cloth, 4-scraper blade, 101-air inlet pipe, 102-extraction pipe, 103-material spreading plate, 104-vibration motor, 201-guide plate, 202-baffle, 203-guide plate, 204-rubber hammer, 301-air blowing pipe, 302-partition plate, 401-conduction plate. Detailed Implementation

[0019] The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments, but this is not intended to limit the present invention.

[0020] Example 1, such as Figures 1-6 As shown, a drying device for atorvastatin calcium intermediate M4 tablets includes a housing 1; the housing 1 is provided with a feed inlet 1001; the housing 1 is provided with a discharge outlet 1002; It also includes a vibration drying assembly, an electrically controlled drive roller 2, an intercepting cloth 3, a flow guiding assembly, and a scraper 4; the vibration drying assembly is installed on the housing 1; four electrically controlled drive rollers 2 arranged in a rectangular pattern are installed on the housing 1; each pair of electrically controlled drive rollers 2 that are opposite each other rotate together and are connected to an intercepting cloth 3; the intercepting cloth 3 is in a ring shape with its ends connected; two collection chambers 1003 that are symmetrically arranged on the housing 1 are opened; each intercepting cloth 3 is located in the corresponding collection chamber 1003 on the side away from the housing 1; a flow guiding assembly is installed inside the housing 1; a scraper 4 is connected to each collection chamber 1003; each scraper 4 is set in an inclined state with the front higher than the back, which is conducive to the scraped medicine powder falling into the collection chamber 1003 along the scraper 4.

[0021] The vibrating drying assembly includes an air inlet pipe 101, an exhaust pipe 102, a material spreading plate 103, and a vibrating motor 104; two air inlet pipes 101 are fixedly connected and connected to the lower part of the box body 1, and are arranged symmetrically on the left and right; two exhaust pipes 102 are fixedly connected and connected to the upper side of the box body 1, and are arranged symmetrically on the left and right; the suction port of each exhaust pipe 102 is located in the inner ring area of ​​the corresponding intercepting cloth 3; a material spreading plate 103 is fixedly connected inside the box body 1; several air holes are opened on the material spreading plate 103; two vibrating motors 104 are fixedly connected to the box body 1, and are arranged symmetrically on the left and right.

[0022] The flow guide assembly comprises guide plates 201, baffle plates 202 and flow guide plates 203; two left-right symmetrical guide plates 201 are fixedly connected in the box 1; all the guide plates 201 jointly form an eight-shaped structure; the baffle plate 202 is fixedly connected in the box 1; the baffle plate 202 is located above all the guide plates 201; two left-right symmetrical storage cavities 1004 are formed in the box 1; each storage cavity 1004 is in communication with the space above the guide plate 201 in the box 1; the flow guide plate 203 is fixedly connected in the box 1; the flow guide plate 203 is located above the paving plate 103; the flow guide plate 203 is made of rubber.

[0023] The rubber hammer 204 is further included; the flow guide plate 203 is rotatably connected with a plurality of rubber hammers 204 on the upper side.

[0024] The air blowing pipe 301 is further included; the air blowing pipe 301 is fixedly connected and communicated with the upper side of the box 1; each air blowing pipe 301 is located in the inner ring area of the corresponding intercepting cloth 3 and is attached to the side of the intercepting cloth 3 facing the collecting cavity 1003.

[0025] The partition plate 302 is further included; two left-right symmetrical partition plates 302 are fixedly connected in the box 1; the partition plate 302 is located in the inner ring area of the corresponding intercepting cloth 3; the partition plate 302 is used for separating the air suction pipe 102 and the air blowing pipe 301.

[0026] In order to make the medicine powder enter the collecting cavity 1003 and accumulate at the back of the collecting cavity 1003, the bottom of the collecting cavity 1003 is set to gradually decrease from front to back, so that the medicine powder is far away from the air blowing pipe 301, which is beneficial to reduce the influence of the air blowing pipe 301 on the medicine powder in the collecting cavity 1003 and reduce the dust of the medicine powder in the collecting cavity 1003.

[0027] In order to prevent the medicine powder and tablet particles collected in the collecting cavity 1003 and the storage cavity 1004 from being continuously dried by the temperature conducted by the box 1, avoid the degradation of the active ingredients of the medicine due to excessive drying, and further avoid the decrease of the effect of the recycled medicine powder, a heat insulation plate is arranged on the side of each collecting cavity 1003 and each storage cavity 1004 facing the middle part of the box 1.

[0028] In the drawings of the application, the side where the feed inlet 1001 is located is the rear side, and the side where the discharge outlet 1002 is located is the front side.

[0029] When the atorvastatin calcium tablets are dried, the vibration motor 104 is controlled to drive the box body 1 to vibrate, so that the laying plate 103 vibrates with the box body 1. Then, the external hot air supply device is controlled to transmit hot air from the air inlet pipe 101 to the box body 1, and the external air pump is controlled to draw air from the air outlet pipe 102 through the interception cloth 3 to the box body 1, so that the hot air flows in the box body 1. Then, the external feeding device feeds the tablets from the feeding port 1001 into the box body 1, so that the tablets vibrate on the laying plate 103. In this process, the hot air entering the box body 1 passes through the air holes on the laying plate 103 from bottom to top, and the tablets on the laying plate 103 are dried. At the same time, the tablets move towards the discharge port 1002 while vibrating on the laying plate 103. In this process, the tablets rub against each other, and the tablets rub against the laying plate 103, so that the active ingredients and excipients on the surface of the tablets form fine powder. Under the action of the suction force of the air outlet pipe 102, the air flow wraps the fine powder and adheres it to the interception cloth 3. The interception cloth 3 intercepts the fine powder to prevent water vapor from being mixed with the fine powder and adhering to the air outlet pipe 102. This avoids wasting the fine powder and reduces the workload of subsequent equipment cleaning.

[0030] At the same time that the interception cloth 3 intercepts the fine powder, the electric control driving roller 2 is controlled to rotate clockwise from the perspective of looking from top to bottom, driving the interception cloth 3 to rotate clockwise. The interception cloth 3 carries the fine powder adhering thereto from the box body 1 to the collection cavity 1003. When the interception cloth 3 carries the fine powder into the collection cavity 1003, the interception cloth 3 contacts the scraper 4, which scrapes the fine powder adhering to the interception cloth 3 into the collection cavity 1003. This prevents the fine powder from being dried for a long time on the interception cloth 3, avoids degradation of the active ingredients of the medicine due to excessive drying, and further avoids a decrease in the effectiveness of the recovered fine powder. However, considering that the interception cloth 3 is made of flexible material, when the scraper 4 scrapes the fine powder off the interception cloth 3, the interception cloth 3 may deform slightly due to vibration of the box body 1, so that the scraper 4 cannot tightly adhere to the interception cloth 3, and the scraper 4 cannot completely scrape the fine powder tightly adhering to the interception cloth 3. Therefore, after the interception cloth 3 carries the fine powder into the collection cavity 1003, the fine powder on the interception cloth 3 first passes through the air blowing pipe 301. At this time, the external air pump is controlled to blow air from the inner ring area of the interception cloth 3 into the collection cavity 1003 through the air blowing pipe 301, so that the fine powder tightly adhering to the interception cloth 3 is blown to be loose, facilitating the subsequent scraping of the fine powder tightly adhering to the interception cloth 3 by the scraper 4 into the collection cavity 1003. This causes the fine powder tightly adhering to the interception cloth 3 to be separated therefrom and collected, enhancing the collection effect of the fine powder.

[0031] When the intercepted powder on the intercepting cloth 3 is scraped by the scraping piece 4 into the collecting cavity 1003, the vibration of the box body 1 causes the powder to accumulate at the rear part of the collecting cavity 1003 along the bottom of the collecting cavity 1003 arranged in a gradually lowered state from front to rear, so that the powder is far away from the blowing pipe 301, which is conducive to reducing the influence of the airflow blown out by the blowing pipe 301 on the powder in the collecting cavity 1003, reducing the situation that the powder in the collecting cavity 1003 is blown up and then adheres to the intercepting cloth 3 again, reducing the problem that the intercepting cloth 3 carrying the powder rotates to the inside of the box body 1 again to intercept the powder, thereby avoiding the situation that the powder in the box body 1 cannot be collected by adhering to the intercepting cloth 3 along the airflow due to the intercepting cloth 3 being covered by the powder blown up, and ensuring the interception and collection effect of the powder in the box body 1.

[0032] When the intercepting cloth 3 rotates to intercept and collect the powder, the partition plate 302 separates the air suction pipe 102 and the collecting cavity 1003, preventing the suction force of the air suction pipe 102 from acting on the collecting cavity 1003 through the intercepting cloth 3, avoiding the collected powder in the collecting cavity 1003 from being suctioned and adhered to the intercepting cloth 3 again by the air suction pipe 102, and ensuring the collection effect of the powder in the collecting cavity 1003. At the same time, the airflow blown out by the blowing pipe 301 is blocked by the partition plate 302, preventing the airflow blown out by the blowing pipe 301 from blowing off the powder adhered by the intercepting cloth 3 towards the inside of the box body 1, and ensuring the interception and collection effect of the intercepting cloth 3.

[0033] When the hot airflow enters the inside of the box body 1 from the air inlet pipe 101, the guide plate 201 arranged in a spreader shape guides the hot airflow to the lower middle part of the material laying plate 103, as shown in Figure 6 After the hot airflow passes through the material laying plate 103, it flows to the upper left part and the upper right part of the material laying plate 103 under the action of the suction force of the air suction pipe 102 and contacts the intercepting cloth 3, so that the hot airflow fully dries the tablets on the material laying plate 103, preventing the hot airflow blown out from the air inlet pipe 101 from being directly lifted and sucked away by the air suction pipe 102, avoiding poor drying effect of the tablets located in the middle part of the material laying plate 103, and enhancing the drying effect of the tablets. At the same time, after the hot airflow passes through the material laying plate 103, it contacts the flow guide plate 203, which blocks the hot airflow and guides it to the left side and the right side of the material laying plate 103, so that the hot airflow flows horizontally and contacts the tablets on the material laying plate 103, fully drying the tablets on the material laying plate 103, and enhancing the effect of uniformly drying the tablets.

[0034] When the guide plate 201 guides the hot air flow, the tablets on the material laying plate 103 are broken due to collision. The small particle tablets after breaking are difficult to be blown upward by the hot air flow rising through the material laying plate 103 due to their large mass, and are easy to fall downward through the air holes of the material laying plate 103. The drug powder is easy to be adhered to the intercepting cloth 3 by the hot air flow due to its small mass. The falling small particle tablets are guided to the guide plate 201 by the baffle 202, so that the guide plate 201 receives the falling small particle tablets and vibrates the small particle tablets along the inclined guide plate 201 to the collection cavity 1004 for collection, preventing the small particle tablets from falling to the bottom of the box body 1 and being continuously baked by the hot air, avoiding over-drying of the small particle tablets, improving the active ingredients of the recovered small particle tablets, and improving the drug efficacy of the recovered small particle tablets. At the same time, the heat insulation plates arranged on one side of the middle part of the box body 1 in the collection cavity 1003 and the collection cavity 1004 insulate the collection cavity 1003 and the collection cavity 1004 from the inside of the box body 1, preventing the drug powder and tablet particles collected in the collection cavity 1003 and the collection cavity 1004 from being continuously dried by the temperature conducted by the box body 1, avoiding degradation of the active ingredients of the drug due to over-drying of the drug powder, and further avoiding reduction of the drug efficacy of the recovered drug powder.

[0035] It is also considered that when the guide plate 203 guides the hot air flow to the left and right sides of the material laying plate 103, the drug powder in the tablets contacts the guide plate 203 with the air flow, and at the same time, due to the presence of water vapor in the tablets, the drug powder is adhered to the lower side of the guide plate 203 due to the water vapor. At this time, the guide plate 203 is vibrated by the box body 1, and the rubber hammer 204 knocks the guide plate 203, which vibrates and falls off the drug powder adhered to the lower side of the guide plate 203 after being dried, preventing the drug powder from being continuously dried for a long time due to its adhesion to the lower side of the guide plate 203, avoiding degradation of the active ingredients of the drug due to over-drying of the drug powder, and improving the drug efficacy of the recovered drug powder.

[0036] In example 2, based on example 1, as shown in Figure 4 and Figure 5 It further includes a conduction plate 401. The upper side of the material laying plate 103 is fixedly connected with a plurality of rectangular conduction plates 401. Each conduction plate 401 is fixedly connected with the lower side of the guide plate 203.

[0037] In order to enhance the knocking force of the rubber hammer 204 knocking the guide plate 203 and improve the vibration effect of the material laying plate 103 when the guide plate 203 is knocked, each of the two conduction plates 401 opposite to each other is located on the same horizontal line with the corresponding rubber hammer 204.

[0038] Also consider that when the tablets on the paving plate 103 are broken due to collision, the small broken tablets are easy to block the air holes on the paving plate 103, so that the air permeability of the paving plate 103 is reduced, and the drying effect on the tablets is reduced. The specific solution process is as follows: When the box 1 vibrates and drives the rubber hammer 204 to knock the guide plate 203, the knocking force of the rubber hammer 204 knocking the guide plate 203 is transmitted to the paving plate 103 through the transmission plate 401, so that the paving plate 103 is subjected to the impact force of the guide plate 203 being knocked by the rubber hammer 204 on the basis of being driven to vibrate by the box 1. It is beneficial to vibrate the small tablets of the paving plate 103 stuck in the air holes to the guide plate 201 below, prevent the air holes on the paving plate 103 from being blocked to reduce the air permeability, avoid the tablets from not being fully contacted with the hot air flow, and ensure the drying effect on the tablets.

[0039] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application and not to limit the protection scope of the present application. Although the present application has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present application can be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present application.

Claims

1. A atorvastatin calcium intermediate M4 tablet drying equipment, comprising a box (1); The box (1) is provided with feed inlet (1001); The box (1) is provided with discharge gate (1002); It is characterized by, Also include a vibration drying assembly, electric control transmission roller (2), intercept cloth (3), guide assembly and scraper (4); The box (1) is provided with a vibration drying assembly for vibrating and drying the tablets; The box (1) is provided with a plurality of electric control transmission rollers (2); Every two electric control transmission rollers (2) opposite to each other are rotatably connected with an intercept cloth (3) for intercepting and collecting powder; The intercept cloth (3) is annular with head and tail connected; The box (1) is provided with a plurality of collecting cavities (1003); Every intercept cloth (3) is located in the corresponding collecting cavity (1003) on the side away from the box (1); The box (1) is provided with a guide assembly for guiding hot air flow to improve drying effect; Every collecting cavity (1003) is connected with a scraper (4) for scraping the powder on the intercept cloth (3); Every scraper (4) is provided in an inclined state with front high and rear low.

2. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 1, characterized in that, The vibration drying assembly includes an air inlet pipe (101), an air outlet pipe (102), a laying plate (103) and a vibration motor (104); The lower part of the box (1) is fixedly connected and communicated with a plurality of air inlet pipes (101) for supplying hot air flow; The upper side of the box (1) is fixedly connected and communicated with a plurality of air outlet pipes (102); The suction port of every air outlet pipe (102) is located in the inner ring area of the corresponding intercept cloth (3); The laying plate (103) for carrying tablets is fixedly connected in the box (1); A plurality of air holes are formed in the laying plate (103); A plurality of vibration motors (104) are fixedly connected to the box (1).

3. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 2, wherein the drying apparatus is characterized by, The guide assembly includes a guide plate (201), a baffle (202) and a guide plate (203); A plurality of guide plates (201) for guiding hot air flow are fixedly connected in the box (1); All guide plates (201) jointly form an eight-shaped; The baffle (202) for guiding tablet particles is fixedly connected in the box (1); The baffle (202) is located above all guide plates (201); A plurality of receiving cavities (1004) are formed in the box (1); Every receiving cavity (1004) is in communication with the space above the guide plate (201) in the box (1); The guide plate (203) for guiding hot air flow is fixedly connected in the box (1); The guide plate (203) is located above the laying plate (103); The guide plate (203) is made of rubber material.

4. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 3, wherein the drying apparatus is characterized by, Also include a rubber hammer (204); A plurality of rubber hammers (204) for knocking and vibrating the guide plate (203) are rotatably connected to the upper side of the guide plate (203).

5. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 1, wherein the drying apparatus is characterized by, Also include a blowing pipe (301); The upper side of the box (1) is fixedly connected and communicated with a blowing pipe (301) for cleaning the powder on the intercept cloth (3); Every blowing pipe (301) is located in the inner ring area of the corresponding intercept cloth (3) and is attached to the side of the intercept cloth (3) facing the collecting cavity (1003).

6. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 5, wherein the drying apparatus is characterized by, Also include a partition (302); A plurality of partitions (302) for blocking the suction air flow of the air outlet pipe (102) are fixedly connected in the box (1); The partition (302) is located in the inner ring area of the corresponding intercept cloth (3); The partition (302) is used to separate the air outlet pipe (102) and the blowing pipe (301).

7. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 5, wherein the drying apparatus is characterized by, The bottom of the collecting cavity (1003) is arranged in a gradually lowered state from front to back.

8. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 3, wherein the drying apparatus is characterized by, Each collecting cavity (1003) and each containing cavity (1004) are provided with a heat insulation plate towards one side of the middle part of the box (1).

9. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 4, wherein the drying apparatus is characterized by, The conductive plate (401) is further included; a plurality of conductive plates (401) for conducting the knocking force are fixedly connected to the upper side of the paving plate (103); each conductive plate (401) is fixedly connected to the lower side of the flow guide plate (203).

10. The atorvastatin calcium intermediate M4 tablet drying apparatus according to claim 9, wherein the drying apparatus is characterized by, Each of the two conductive plates (401) opposite to each other is located on the same horizontal line as the corresponding rubber hammer (204).

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