Soothing composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to a soothing composition as well as a preparation method and application thereof. The soothing composition is prepared from the following components in percentage by mass: 10 to 20 percent of polyglycerol-10 laurate and other emulsifiers, 10 to 20 percent of palmitamide MEA, 5 to 15 percent of acetamide MEA, 2 to 8 percent of stearyl glycyrrhetinate, 5 to 15 percent of squalane and 0.5 to 2 percent of ceramide NP. The invention also provides a preparation method of the soothing composition, and the soothing composition is quick and long-acting in soothing effect, and can synchronously improve the barrier, anti-inflammatory and moisturizing effects.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a soothing composition, its preparation method, and its application. Background Technology

[0002] In today's cosmetics and skincare industry, skin soothing and repair remain core research hotspots. In recent years, as consumers have become increasingly concerned about their skin health, coupled with increasing environmental pressures and the impact of climate change, skin sensitivity has become more prevalent. This has led to an explosive growth in demand for products that can effectively soothe the skin and alleviate discomfort.

[0003] In traditional soothing cosmetics, a common approach is to add exogenous cannabinoid receptor modulators to regulate cannabinoid receptors and achieve a soothing effect on the skin. However, these exogenous substances used to modulate cannabinoid receptors, such as cannabis extracts, pose numerous significant safety risks. Therefore, for consumer safety reasons, relevant authorities have explicitly prohibited the use of such substances in cosmetics. This ban has created a significant technological challenge for soothing cosmetics that rely on these exogenous substances, necessitating the search for new and effective solutions.

[0004] On the other hand, existing soothing cosmetics have significant limitations in terms of efficacy. Most products struggle to simultaneously address both soothing and repairing effects. It's important to understand that when skin is stimulated by external factors, it not only urgently needs immediate relief from discomfort such as redness and stinging, but also needs to activate its self-repair mechanisms to return to a healthy and stable state. However, most products on the market currently only focus on addressing one aspect of the problem—soothing or repairing—failing to provide comprehensive, one-stop care for the skin.

[0005] More notably, even regarding the soothing effects heavily advertised in the products, the actual effectiveness of existing products in relieving pain and itching is unsatisfactory. In actual use, even after applying these products, consumers typically experience a lack of timely, effective, and lasting relief from skin pain and itching. This falls far short of consumers' expectations for rapid and significant relief from skin discomfort, severely impacting their user experience and highlighting the shortcomings of current products in this category in achieving their intended effects.

[0006] In view of the above-mentioned technologies, the inventors believe that it is necessary to develop a new soothing composition with good calming effects. Summary of the Invention

[0007] To address the technical deficiencies of the prior art, this application provides a soothing composition, its preparation method, and its application.

[0008] In a first aspect, this application provides a soothing composition, employing the following technical solution: A soothing composition comprising, by weight percentage: 10-20% polyglycerol-10 laurate, 10-20% palmitamide MEA, 5-15% acetamide MEA, 2-8% stearyl glycyrrhizate, 5-15% squalane, 0.5-2% ceramide NP, and the balance being solvent.

[0009] By employing the above-mentioned technical solutions, the core value of this soothing composition lies in constructing a deeply synergistic efficacy network of "barrier repair - anti-inflammatory soothing - moisturizing and water-locking," the advantage of which stems from the precise complementarity and structural compatibility of the mechanisms of action of each component. Ceramide NP, as a core component of the intercellular lipids of the stratum corneum, can directly fill the lipid gaps in damaged skin, providing adhesive support for keratinocytes, promoting stratum corneum thickening, and structurally rebuilding the skin's physical barrier. Palmitamide MEA and acetamide MEA, as endogenous lipids homologous to the human body, activate the skin's endocannabinoid system, synergistically regulating the expression of lipid synthesis genes with ceramide NP, while inhibiting ceramidinase activity to reduce the degradation of synthesized lipids, forming a "replenishment-synthesis-preservation" barrier repair closed loop; on the other hand, they can regulate the NF-κB inflammatory pathway, blocking the transmission of pro-inflammatory signals from the upstream of the inflammatory response. Stearyl glycyrrhetinic acid ester focuses on the downstream of inflammation, targeting and inhibiting the release of pro-inflammatory factors such as IL-1α and TNF-α, forming a dual anti-inflammatory mechanism of "upstream regulation + downstream inhibition" with MEA-like components, precisely relieving symptoms of skin sensitivity. Squalane can integrate into the sebum film and form a lipid bilayer with ceramide NP, filling the gaps in the stratum corneum and enhancing its water-locking ability. In addition, squalane also has barrier repair functions and can play a certain repair role. Polyglycerol-10 laurate, with its suitable HLB value, effectively emulsifies fat-soluble, water-soluble, and semi-fat-soluble ingredients, avoiding system stratification or component separation. It provides a stable carrier for the uniform dispersion and efficacy of each active ingredient, enabling a virtuous cycle of barrier repair, anti-inflammation, and moisturizing effects, overcoming the limitation of single ingredients only addressing localized problems.

[0010] Preferably, by weight percentage, it comprises: 15% polyglycerol-10 laurate, 15% palmitamide MEA, 10% acetamide MEA, 5% stearyl glycyrrhetinic acid ester, 10% squalane and 1% ceramide NP.

[0011] By adopting the above technical solution, the specific proportions of each ingredient in the optimized formula are a balanced scheme derived from synergistic mechanism optimization, achieving a balance between maximizing efficacy and skin tolerance. In this ratio, the content of polyglycerol-10 laurate is sufficient to encapsulate and emulsify all active ingredients, ensuring long-term system stability; the combination of palmitamide MEA and acetamide MEA concentrations maximizes the activation of the endocannabinoid system's regulatory effects, strengthening barrier lipid synthesis and improving the blocking efficiency of anti-inflammatory signals; the amount of stearyl glycyrrhetinic acid ensures potent inhibition of pro-inflammatory factors while avoiding skin irritation that may be caused by high concentrations; and the ratio of ceramide NP to squalane precisely matches the lipid needs of the stratum corneum, playing a core role in barrier repair while reducing moisture loss during the barrier repair process through synergistic moisturizing. This precise formulation allows each ingredient to overcome efficacy competition, creating a synergistic effect of "1+1>2," achieving an optimal balance between gentleness and efficacy in the composition.

[0012] Preferably, the solvent comprises, by weight percentage of the soothing composition, 20-30% of an organic alcohol and 100% deionized water.

[0013] By adopting the above technical solution, the solvent system uses a combination of organic alcohol and deionized water, providing a suitable dissolution environment and stable foundation for the entire formulation. Organic alcohol, as an excellent co-solvent for lipid-soluble active ingredients, can effectively improve the solubility of ingredients such as stearyl glycyrrhizate and ceramide NP, preventing precipitation or crystallization due to insufficient dissolution and ensuring that the active ingredients are uniformly dispersed in the system. Deionized water, as the core carrier of the aqueous phase, not only provides a dissolution medium for water-soluble ingredients such as acetamide MEA, but also synergistically regulates the polarity of the system with organic alcohol, optimizing the emulsification conditions of polyglycerol-10 laurate and promoting the full integration of the oil and water phases. Simultaneously, the hydroxyl structure of organic alcohol can form hydrogen bonds with water molecules, helping to enhance the system's moisturizing ability and forming a multi-dimensional moisturizing network with lipid moisturizers and ceramide NP, further strengthening the skin's hydration state and creating a favorable environment for barrier repair.

[0014] Preferably, the organic alcohol is a mixture of hexyldecyl alcohol and 1,3-propanediol, with a mass ratio of (1-2):(19-28).

[0015] By employing the above technical solution, hexyldecyl alcohol and 1,3-propanediol are combined in a specific ratio to achieve a triple benefit of "solution enhancement, system stability, and synergistic efficacy." Hexyldecyl alcohol, as a Guerbert alcohol solvent, possesses a unique branched molecular structure that can break the crystallization and aggregation characteristics of ceramide NP, significantly improving its dissolution efficiency and dispersion uniformity, ensuring that ceramide NP can participate in barrier repair at the molecular level. 1,3-propanediol can synergistically interact with polyglycerol-10 laurate, reducing the viscosity of the aqueous phase to improve dispersion efficiency during homogenization, while simultaneously enhancing the solubility of lipid-soluble components in the aqueous phase, fundamentally avoiding system stratification. The precise control of the ratio of the two ensures both stable dissolution and efficacy release of ceramide NP, and, leveraging the moisturizing properties of 1,3-propanediol, forms a moisturizing synergy with squalane and ceramide NP, further consolidating the barrier repair results.

[0016] Secondly, this application provides a method for preparing a soothing composition, using the following technical solution: A method for preparing a soothing composition includes the following steps: S1: Polyglycerol-10 lauryl ester, palmitamide MEA, and stearyl glycyrrhetinic acid ester are stirred evenly to obtain the first mixture; S2: Mix the lipid moisturizer, ceramide NP and part of the solvent evenly to obtain a second mixture; S3: Mix acetamide MEA and the remaining solvent thoroughly to obtain a third mixture; S4: Mix the first, second and third mixtures thoroughly to obtain the soothing composition.

[0017] By adopting the above technical solution, the integrity of the efficacy of each active ingredient and the uniformity of the system are ensured from the process level. S1, which separately mixes polyglycerol-10 laurate and lipid-soluble components, ensures that the emulsifier and lipid phase components are fully combined, laying the foundation for subsequent emulsification. S2 specifically treats lipid moisturizers, ceramide NP, and some solvents, avoiding dissolution conflicts caused by direct contact between ceramide NP and water-soluble components. S3 separately dissolves acetamide MEA and the remaining solvent, ensuring their full dispersion in the aqueous phase. This phase separation treatment method is adapted to the physicochemical properties of different components, avoiding efficacy interference caused by polarity differences in the initial stage of mixing. Then, the unified stirring in S4 achieves deep fusion of the three phase components, ensuring that the active ingredients are uniformly dispersed in the system, providing process support for the stable performance of the overall efficacy.

[0018] Preferably, the stirring conditions in step S1 are 200-400 r / min and heating to 80-85°C; the stirring conditions in step S2 are 800-1200 r / min and heating to 80-85°C; the stirring conditions in step S3 are 800-1200 r / min and heating to 70-80°C; and the stirring conditions in step S4 are 2500-3000 r / min for 5-10 minutes, followed by cooling to 35-40°C after uniform mixing.

[0019] By adopting the above technical solutions, the stirring speed and temperature can be precisely controlled, ensuring the stability of the system while fully preserving the efficacy of the active ingredients.

[0020] Thirdly, this application provides a cosmetic product, which adopts the following technical solution: A cosmetic product comprising the aforementioned soothing composition.

[0021] By adopting the above-mentioned technical solution, this soothing composition is applied to cosmetics, achieving a perfect match between the efficacy of the active ingredients and the skincare scenario. The composition itself has excellent system compatibility; its stable emulsified state allows it to easily integrate into various cosmetic matrices without negatively impacting the original texture, feel, or stability of the product. Simultaneously, the composition's core efficacy of "barrier repair, anti-inflammatory soothing, and moisturizing" highly matches the skincare needs of cosmetics in addressing dryness, sensitivity, and redness. This imbues cosmetics with precise soothing and repairing value, overcoming the shortcomings of ordinary cosmetics that only focus on basic care and lack targeted efficacy. Consumers can simultaneously receive dual care of barrier strengthening and sensitivity soothing during their daily skincare routine, significantly expanding the application scenarios and practical value of soothing active ingredients.

[0022] Preferably, the cosmetics include face creams, lotions, serums, and face masks.

[0023] By employing the aforementioned technical solutions, and based on the precise adaptation of ingredient characteristics to skincare scenarios, the creams and lotions are moisturizing and can hold a high proportion of lipid components, making them suitable for daily care of dry and sensitive skin. Through continuous application, they form a protective film on the skin surface, prolonging the action time of active ingredients and strengthening barrier repair and moisture retention. The serum has a light texture, allowing for higher penetration of active ingredients, making it suitable for emergency care when skin experiences sudden sensitivity such as redness and stinging. It can quickly deliver anti-inflammatory and repairing ingredients to the stratum corneum. The mask, through short-term application, creates a sealed environment, accelerating the skin's absorption of active ingredients and achieving highly effective soothing in intensive care scenarios. The adaptability design of different formulations allows the soothing composition to be tailored to different skin types and care needs, enhancing the product's versatility and flexibility.

[0024] In summary, this application has the following beneficial effects: 1. This application constructs a dual-core system of "multi-target anti-inflammatory + biomimetic barrier repair". At the anti-inflammatory level, a synergistic pathway of "upstream regulation + downstream inhibition" is formed: palmitamide MEA and acetamide MEA, as endogenous lipids, activate the skin's endocannabinoid system, downregulating the activity of the NF-κB inflammatory pathway upstream and reducing the synthesis of pro-inflammatory factors; stearyl glycyrrhetinic acid ester targets downstream, directly inhibiting the release of already generated pro-inflammatory factors such as IL-1α and TNF-α. The synergistic effect of both significantly improves the inflammation sensitivity index (EI) – the EI value decreased from 26.08 to 24.29 after 15 minutes of use, an improvement rate of 6.86%, and after 14 days of continuous use, the EI value decreased to 16.49, an improvement rate as high as 36.77%, far superior to the effect of a single anti-inflammatory ingredient. At the barrier repair level, a closed-loop synergy of "direct replenishment + promotion of synthesis + prevention of degradation" is constructed: ceramide NP directly fills the lipid gap in the stratum corneum, acetamide MEA promotes the autonomous generation of lipids through gene regulation, and palmitamide MEA inhibits ceramidinase activity to reduce lipid degradation. The three, together with squalane, form a "skeleton-filling" structure—ceramide NP builds the barrier skeleton, and squalane fills the gaps to strengthen water retention, reducing the transepidermal water loss rate from the initial 11.94% to 9.23% after 14 days, an improvement rate of 22.7%. At the same time, the moisture content of the stratum corneum increases from 34.53% to 45.21%, an improvement rate of 30.93%, achieving a simultaneous improvement in barrier function and moisturizing effect.

[0025] 2. The system described in this application is relatively stable, ensuring a soothing effect. Polyglycerol-10 laurate, with its suitable HLB value, efficiently emulsifies the lipid-soluble palmitamide MEA, water-soluble acetamide MEA, and semi-lipid-soluble ceramide NP, preventing component separation or stratification. The organic alcohol is a specific blend of hexyldecyl alcohol and 1,3-propanediol. Hexyldecyl alcohol disrupts the crystal aggregation of ceramide NP to improve dissolution efficiency, while 1,3-propanediol, as a synergistic emulsifier, optimizes the system's dispersibility. The combination of these two ensures uniform dispersion of the active ingredients. The preparation process further enhances stability through phase separation mixing and precise parameter control: low-speed heating in S1 ensures full dissolution of lipid-soluble components; high-speed dispersion in S2 and S3 improves the homogeneity of each phase; high-speed homogenization in S4 achieves deep fusion of the three phases; and cooling treatment preserves the activity of the components, ensuring long-term storage without abnormalities and stable efficacy of the active ingredients. This "formula synergy + process synergy" design allows the composition to be easily adapted to various cosmetic formulations such as face creams and lotions, preserving the original skin feel of the product while giving it precise soothing and repairing value, providing an efficient and practical solution for sensitive skin care. Detailed Implementation

[0026] The present invention will be further described below with reference to embodiments, but this does not constitute any limitation on the present invention. Any limited modifications made within the scope of the claims of the present invention are still within the scope of the claims of the present invention.

[0027] The raw materials used in the following examples and comparative examples are all commercially available products.

[0028] Palmitamide MEA was purchased from Nikko Chemical Trading (Shanghai) Co., Ltd. Acetamide MEA was purchased from Weinan Changtong Pharmaceutical Technology Co., Ltd. Stearyl glycyrrhetinic acid ester was purchased from Chenfeng Natural Herbs (Beijing) Technology Co., Ltd. Ceramide NP was purchased from Croda Chemicals (Shanghai) Co., Ltd. Example 1

[0029] A soothing composition comprising, by weight percentage: 20% polyglycerol-10 laurate, 10% palmitamide MEA, 5% acetamide MEA, 2% stearyl glycyrrhetinic acid ester, 15% squalane, 0.5% ceramide NP, 1% hexyldecyl alcohol, 19% 1,3-propanediol and to a final volume of 100% deionized water.

[0030] This embodiment also provides a method for preparing the above-mentioned soothing composition, the steps of which are as follows: S1: Polyglycerol-10 laurate, palmitamide MEA, and stearyl glycyrrhetinic acid ester are stirred at 200 r / min and heated to 80°C until completely dissolved and homogeneous to obtain the first mixture for later use.

[0031] S2: Squalane, ceramide NP and hexyldecyl alcohol are stirred and heated to 80°C at 800 r / min until homogeneous to obtain a second mixture for later use.

[0032] S3: Mix water, 1,3-propanediol, and acetamide MEA at 800 r / min and heat to 70°C to obtain a third mixture, which is then set aside.

[0033] S4: Mix the first, second and third mixtures together, homogenize at 2500 r / min for 5 minutes, stir evenly, and then cool to 35℃ to obtain the finished product.

[0034] Example 2

[0035] A soothing composition comprising, by weight percentage: 15% polyglycerol-10 laurate, 15% palmitamide MEA, 10% acetamide MEA, 5% stearyl glycyrrhetinic acid ester, 10% squalane, 1% ceramide NP, 1% hexyldecyl alcohol, 25% 1,3-propanediol and to a final volume of 100% deionized water.

[0036] This embodiment also provides a method for preparing the above-mentioned soothing composition, the steps of which are as follows: S1: Polyglycerol-10 laurate, palmitamide MEA, and stearyl glycyrrhetinic acid ester are stirred at 300 r / min and heated to 82°C until completely dissolved and homogeneous to obtain the first mixture for later use.

[0037] S2: Squalane, ceramide NP and hexyldecyl alcohol are stirred and heated to 82°C at 1000 r / min until homogeneous to obtain a second mixture for later use.

[0038] S3: Mix water, 1,3-propanediol, and acetamide MEA at 1000 r / min and heat to 75°C to obtain a third mixture, which is then set aside.

[0039] S4: Mix the first, second and third mixtures together, homogenize at 2800 r / min for 8 minutes, stir evenly, and then cool to 37℃ to obtain the finished product.

[0040] Example 3

[0041] A soothing composition comprising, by weight percentage: 10% polyglycerol-10 laurate, 20% palmitamide MEA, 15% acetamide MEA, 8% stearyl glycyrrhetinic acid ester, 5% squalane, 2% ceramide NP, 2% hexyldecyl alcohol, 28% 1,3-propanediol and to a final volume of 100% deionized water.

[0042] This embodiment also provides a method for preparing the above-mentioned soothing composition, the steps of which are as follows: S1: Polyglycerol-10 laurate, palmitamide MEA, and stearyl glycyrrhetinic acid ester are stirred at 400 r / min and heated to 85°C until completely dissolved and homogeneous to obtain the first mixture for later use.

[0043] S2: Squalane, ceramide NP and hexyldecyl alcohol are stirred and heated to 85°C at 1200 r / min until homogeneous to obtain a second mixture for later use.

[0044] S3: Mix water, 1,3-propanediol, and acetamide MEA at 1200 r / min and heat to 80°C to obtain a third mixture, which is then set aside.

[0045] S4: Mix the first, second and third mixtures together, homogenize at 3000 r / min for 10 minutes, stir evenly, and then cool to 40℃ to obtain the finished product.

[0046] Comparative Example 1 A soothing composition, which differs from Example 2 in that it does not contain palmitamide MEA and acetamide MEA.

[0047] Comparative Example 2 A soothing composition, which differs from Example 2 in that it does not contain stearyl glycyrrhetinic acid ester, squalane, and ceramide NP.

[0048] Comparative Example 3 A soothing composition, differing from Example 2 in that dimethyl glycyrrhizate is used instead of orthoceryl glycyrrhizate.

[0049] Performance testing 1. Stability Test Test subjects: the soothing compositions of Example 2 and Comparative Examples 1-3.

[0050] Test method: Centrifuge the soothing composition samples of Example 2 and the comparative example at 4000 rpm for 30 mins and observe their condition. At the same time, store them in constant temperature ovens at -10℃, 25℃ and 45℃ for 3 months. After returning to room temperature, observe the changes in appearance, odor and whether stratification occurs.

[0051] Test results are shown in Table 1.

[0052] Table 1 Stability test results

[0053] As shown in Table 1, the composition of the present invention is relatively stable and can maintain its stability even under low temperature, high temperature and centrifugation conditions.

[0054] 2. Efficacy Test Test subjects: the soothing compositions of Example 2 and Comparative Examples 1-3.

[0055] Test Methods: 120 volunteers aged 21-55 years with a lactic acid test score greater than 3 and subjective symptoms such as burning, stinging, itching, and tightness, with or without objective signs such as erythema, scaling, and telangiectasia, were selected. These volunteers were randomly divided into 4 groups, corresponding to the soothing composition samples of Example 2 and Comparative Examples 1-3, respectively. Volunteers used the corresponding sample twice daily, morning and evening, at a dosage of 0.5 mL. The transepidermal water loss rate of the volunteers' facial skin was measured using a skin moisture loss meter, the skin moisture content of the volunteers' facial skin was measured using a multi-probe skin efficacy analyzer, and the EI value of the volunteers' facial skin was measured using a multifunctional 3D skin imaging analyzer.

[0056] The EI value is an objective parameter that quantifies the degree of erythema on the skin surface.

[0057] Test results: The measured transepidermal water loss rate, skin moisture content, and EI value are all average values. The improvement rate is calculated using the formula = In the formula: D0 is the baseline value of skin parameters in the test area before the product was used; D t The values ​​are the skin parameters after the product was used on the test area; N is the number of subjects; the specific results are shown in Table 2.

[0058] Table 2 Efficacy Test Results

[0059] As shown in Table 2, the improvement rates of transepidermal water loss, skin stratum corneum moisture content, and EI value of Comparative Example 1 (lacking palmitamide MEA and acetamide MEA) and Comparative Example 2 (lacking stearyl glycyrrhizate, squalane, and ceramide NP) all showed significant declines to varying degrees compared to Example 2. This fully demonstrates the synergistic effect of each component in the soothing composition of the present invention, and that this synergistic effect is irreplaceable.

[0060] Furthermore, in Comparative Example 3, although the improvement rate of various efficacies was somewhat improved compared to Comparative Examples 1 and 2 after replacing the lipophilic stearyl glycyrrhizate in the original formula with an aqueous anti-allergy agent, it was still far lower than that of Example 2. This result further confirms the unique synergistic effect among the components in the soothing composition of the present invention—each component is an indispensable key link in achieving excellent efficacy and has an irreplaceable role.

[0061] Application examples For ease of practical use, the soothing composition of this invention can also be prepared into soothing cosmetic products (such as creams, serums, lotions, and masks). The following example uses a face cream: A soothing face cream, the specific formula of which is shown in Table 3 below.

[0062] Table 3 Soothing Face Cream Formula

[0063] This application example also provides a method for preparing the above-mentioned soothing face cream, including the following steps: S1: Pour the A phase raw material into the reactor in sequence, start mixing and heat to 80-85℃, mix and dissolve evenly, and keep warm for 10 minutes; S2: Pour the B phase raw material into another reactor in sequence, start mixing and heat to 80-85℃ until the mixture is uniformly dissolved; S3: Mix the C phase raw materials together until completely dissolved and set aside; S4: Pour the A-phase raw material obtained in step S1 and the B-phase raw material obtained in step S2 into the same reactor, stir and mix evenly, then lower the temperature to 60-65℃, add the C-phase raw material obtained in step S3, mix and homogenize for 3-5 minutes, and continue stirring and cooling. S5: When the temperature in step S4 is reduced to 40-45℃, add phase D to the reactor and stir until evenly mixed.

[0064] Application example performance test 1. Test subject: Soothing face cream (for example) 2. Test participants: Volunteers aged 21-55 years with a lactic acid test score greater than 3 and subjective symptoms such as burning, stinging, itching, and tightness of the skin, with or without objective signs such as erythema, scaling, and telangiectasia.

[0065] 3. Testing Method: Volunteers used 1mL of the application-specific soothing face cream after cleansing at 8 PM daily. Satisfaction with the soothing face cream was evaluated at 15 minutes, 7 days, and 14 days after application. The scoring criteria (4-point scale): 0 points: no improvement; 1 point: slight improvement; 2 points: moderate improvement; 3 points: significant improvement. Statistical percentage = (Number of participants who felt the product had an improvement effect ÷ Number of valid participants) × 100%. A score ≥ 1 point was recorded as a valid improvement.

[0066] 4. Test Results: The specific results are shown in Table 4.

[0067] Table 4 Performance test results of application examples

[0068] As shown in Table 4, the soothing face cream prepared by the soothing composition of the present invention has a fast onset of action, with an effective rate of over 90% after 15 minutes of use. In addition, the soothing face cream prepared by the soothing composition of the present invention has excellent soothing effects, with an effective rate of 100% for all test items after 14 days of use. This indicates that the soothing face cream prepared by the soothing composition of the present invention does indeed have soothing, moisturizing and repairing effects.

[0069] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.

Claims

1. A soothing composition, characterized in that, By weight percentage: 10–20% polyglycerol-10 laurate, 10–20% palmitamide MEA, 5–15% acetamide MEA, 2–8% stearyl glycyrrhizate, 5–15% squalane, 0.5–2% ceramide NP and the balance being solvent.

2. The soothing composition according to claim 1, characterized in that, By weight percentage, it comprises: 15% polyglycerol-10 laurate, 15% palmitamide MEA, 10% acetamide MEA, 5% stearyl glycyrrhetinic acid ester, 10% squalane and 1% ceramide NP.

3. The soothing composition according to claim 1, characterized in that, The solvent comprises, by weight percentage of the soothing composition, 20-30% of an organic alcohol and 100% deionized water.

4. The soothing composition according to claim 3, characterized in that: The organic alcohol is a compound of hexyldecyl alcohol and 1,3-propanediol, with a mass ratio of (1-2):(19-28).

5. A method for preparing a soothing composition according to any one of claims 1 to 4, characterized in that, Includes the following steps: S1: Polyglycerol-10 lauryl ester, palmitamide MEA, and stearyl glycyrrhetinic acid ester are stirred evenly to obtain the first mixture; S2: Mix the lipid moisturizer, ceramide NP and part of the solvent evenly to obtain a second mixture; S3: Mix acetamide MEA and the remaining solvent thoroughly to obtain a third mixture; S4: Mix the first, second and third mixtures thoroughly to obtain the soothing composition.

6. The method for preparing a soothing composition according to claim 5, characterized in that: The stirring conditions in step S1 are 200-400 r / min and heating to 80-85℃; the stirring conditions in step S2 are 800-1200 r / min and heating to 80-85℃; the stirring conditions in step S3 are 800-1200 r / min and heating to 70-80℃; and the stirring conditions in step S4 are 2500-3000 r / min for 5-10 minutes, and after stirring evenly, cooling to 35-40℃.

7. The use of the soothing composition according to any one of claims 1 to 4 in the preparation of cosmetics.

8. A cosmetic product, characterized in that: Includes a soothing composition as described in any one of claims 1 to 4.

9. A cosmetic product according to claim 8, characterized in that: The cosmetics include face creams, lotions, serums, and face masks.

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