Plant extract multi-effect composition as well as preparation method and application thereof
By combining European larch wood extract, plantain extract, and licorice or bellflower extract in a specific ratio, a multi-effect plant extract composition was prepared, which solved the problem of poor compound effects of plant extracts and achieved significant anti-ultraviolet, antioxidant and anti-inflammatory effects.
Patent Information
- Application Number
- CN202610053882.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-01-15
- Publication Date
- 2026-02-24
AI Technical Summary
In existing technologies, the effects of single plant extracts are limited, and the effects of compound plant extracts are weaker than those of single components, with a lack of research on synergistic effects.
A multi-effect plant extract composition is prepared using a specific ratio of European larch wood extract, plantain extract, and licorice or bellflower extract through a specific preparation method. This composition is used for anti-ultraviolet, free radical scavenging, and anti-inflammatory purposes.
It significantly improved the effect of resisting ultraviolet damage, increased cell survival rate, improved DPPH free radical scavenging rate, and reduced inflammatory factor levels, achieving synergistic effects of anti-ultraviolet, antioxidant and anti-inflammatory.
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Abstract
Description
Technical Field
[0001] This invention relates to the field of cosmetic technology, and more specifically, to a plant extract multi-effect composition, its preparation method, and its application. Background Technology
[0002] Prolonged exposure to ultraviolet (UV) radiation can cause skin damage, leading to photoaging and even skin cancer and other skin diseases. The main mechanisms of UV-induced photoaging include oxidative stress, inflammatory responses, apoptosis, and the degradation of collagen and elastin.
[0003] Compared to traditional cosmetics, cosmetics formulated with plant extracts as active ingredients offer numerous advantages, such as overcoming the reliance on chemically synthesized products, resulting in higher product safety; easier absorption of natural components by the skin, leading to more significant effects; and enhanced functionality. Therefore, the application of plant extracts in cosmetics is an inevitable market trend. Furthermore, plant extracts possess several distinct advantages: wide availability and targeted mechanisms of action. Especially with advancements in modern extraction and analytical techniques, their active ingredients and related mechanisms of action have been gradually discovered and confirmed, demonstrating significant efficacy in sun protection, whitening, anti-aging, and antibacterial applications, making them widely applicable in various cosmetics. Therefore, the application prospects of plant extracts in cosmetics are very broad.
[0004] Relevant patent documents retrieved: This patent, published in China (CN115670985A) on February 3, 2023, discloses a method for preparing an antioxidant skincare product using herbal plant extracts. The product comprises the following components: herbal plant extracts, alcohol, hyaluronic acid, cyclopentamethoxysiloxane, xanthan gum, methylcellulose, glycerin, polyoxyethylene-2-stearyl alcohol ether, ethylhexyl palmitate, and deionized water. The invention produces a highly antioxidant skincare product containing herbal plant extracts. When used as an additive, the herbal plant extracts effectively remove excess oxygen free radicals from the skin, improving or delaying skin aging and the formation of facial pigmentation. It also possesses whitening, moisturizing, skin repair, UV protection, antibacterial and anti-inflammatory properties, and acne and blemish removal effects. However, the specific types and quantities of the herbal plant extracts are not disclosed.
[0005] Relevant non-patent literature retrieved: Journal or book title: Daily Chemical Industry; document title: Cosmetic Plant Raw Materials (I) - Research and Development in Sunscreen Cosmetics; Volume No. 51, Issue No. 1; Publication date: January 2021; This document discloses skin sunburn and photoaging caused by ultraviolet radiation, as well as plant extracts that resist the damage of ultraviolet radiation to the skin. The active ingredients in these plant extracts are compounds containing benzene rings or conjugated structures, such as flavonoids, phenylpropanoids, polyphenols, and carotenoids. Flavonoids include anthocyanins, rutin, quercetin, chalcone A, aspergillus, gentianin, chickpea bud extract A, and silymarin. Many plants are rich in flavonoids, such as ginkgo, sophora japonica, milk thistle, scutellaria baicalensis, licorice, and kudzu root. Phenylpropanoids mainly include ferulic acid, cinnamic acid, caffeic acid, rosmarinic acid, chlorogenic acid, tanshinone, and rhodioloside. Plant polyphenols include catechin, salvianolic acid, gallic acid, and ellagic acid. Carotenoids also exist, mainly including lycopene, astaxanthin, lutein, and β-carotene. However, there is no research on the synergistic compounding of plant extracts.
[0006] The prior art represented by the aforementioned documents has at least the following unresolved technical problems or defects: Single plant extracts have limited effects. When combining different plant extracts, it is necessary to study the appearance, odor, and effects of the combined extracts. Furthermore, due to the interactions between the components, the combined effect of different extracts may be weaker than that of a single ingredient. Therefore, combining plant extracts is not an easy task. Based on this, providing a composition of plant extracts with synergistic effects, significantly enhancing their anti-UV, free radical scavenging, and anti-inflammatory efficacy, is of great significance. Summary of the Invention
[0007] The purpose of this invention is to provide: A plant extract multi-effect composition and its preparation method, and related technologies, to solve technical problems such as providing a plant composition or combination thereof with better anti-ultraviolet effect, free radical scavenging effect and anti-inflammatory effect.
[0008] Terminology Explanation: Unless otherwise defined, all technical terms in this document have the same meanings as commonly understood by one of ordinary skill in the art to which the subject matter of the claims pertains. Unless otherwise stated, all patents, patent inventions, and publications cited in this document are incorporated herein by reference in their entirety. If multiple definitions exist for terms in this document, the definitions in this chapter shall prevail.
[0009] It should be understood that the above brief description and the following detailed description are exemplary and for illustrative purposes only, and do not limit the subject matter of the invention in any way. In this invention, the singular is used in conjunction with the plural unless otherwise specifically stated. It should also be noted that, unless otherwise stated, the use of “or” or “or” means “and / or”. Furthermore, the use of the term “comprising” and other forms such as “including,” “containing,” and “contains” are not limiting.
[0010] The definition of standard chemical terms can be found in the reference "Pharmacopoeia of the People's Republic of China (2020 Edition): China Medical Science and Technology Press: May 2020".
[0011] Unless otherwise stated, conventional methods within the scope of the art, such as crushing and sieving, shall be used.
[0012] Unless specifically defined herein, the use of all commercially available products herein employs standard techniques. For example, it may be carried out using the manufacturer's instructions for use with the kit, or in accordance with methods known in the art or the description of this invention. The techniques and methods described herein can generally be implemented according to conventional methods well known in the art, based on the descriptions in the various summary and more specific documents cited and discussed in this specification.
[0013] In a first aspect, the present invention provides: a plant extract multi-effect composition comprising the following raw materials: European larch wood extract, plantain extract and plant extract A, wherein plant extract A is selected from at least one of licorice extract or platycodon extract.
[0014] The mass ratio of the European larch extract to the plantain extract is (15-25):(5-15).
[0015] (15-25): Any point value or sub-range within the range of (5-15) can achieve the technical effect of the present invention, including but not limited to 15:5, 16:6, 17:7, 18:8, 19:9, 20:10, 21:11, 22:12, 23:13, 24:14, 25:15, and 25:5.
[0016] Specifically, and as a specific embodiment of the present invention, the plant extract multi-effect composition includes the following raw materials: European larch wood extract, plantain extract, and licorice extract.
[0017] Specifically, and as a specific embodiment of the present invention, the plant extract multi-effect composition includes the following raw materials: European larch wood extract, plantain extract, and bellflower extract.
[0018] Specifically, and as a specific embodiment of the present invention, the plant extract multi-effect composition includes the following raw materials: European larch wood extract, plantain extract, licorice extract and platycodon root extract.
[0019] Preferably, it includes the following raw materials: European larch wood extract, plantain extract, licorice extract and bellflower extract.
[0020] The mass ratio of the European larch extract, plantain extract, licorice extract and platycodon extract is (15-25):(5-15):(1-5):(1-3).
[0021] Any point value or sub-range within the range of (15-25): (5-15): (1-5): (1-3) can achieve the technical effect of the present invention, including but not limited to 15:5:1:1, 20:10:2:1, 15:15:2:1, and 25:15:5:3.
[0022] The preparation method of the European larch wood extract is as follows: European larch wood is crushed and sieved, 8-10 times the mass of 60-80wt% ethanol aqueous solution is added, and the mixture is heated and refluxed 2-3 times at an extraction temperature of 45-55℃. The extracts are combined, concentrated, and purified to obtain the European larch wood extract.
[0023] Preferably, the preparation method of the European larch wood extract is as follows: European larch wood is pulverized and passed through a 60-80 mesh sieve to obtain European larch wood powder. 8-10 times the amount of 60-80wt% ethanol aqueous solution is added, mixed evenly, and soaked for 0.5-1.5 hours. After soaking, the mixture is heated under reflux 2-3 times at an extraction temperature of 45-55℃. The extracts are combined and concentrated under reduced pressure at 60-70℃ to obtain a concentrated European larch wood extract. The concentrated extract is passed through a macroporous resin, eluted with an eluent, and the eluent is collected. Ethanol is recovered under reduced pressure to obtain a concentrated European larch wood extract. After dispersion with an appropriate amount of purified water, the supernatant is removed, filtered, and the precipitate is obtained. The precipitate is dried under reduced pressure at 55-65℃ to obtain the European larch wood extract.
[0024] The preparation method of the plantain extract is as follows: plantain is crushed and sieved, 8-12 times the mass of 50-70wt% ethanol aqueous solution is added, and the mixture is heated and refluxed 2-3 times at an extraction temperature of 45-55℃. The extracts are combined, concentrated, and purified to obtain the plantain extract.
[0025] Preferably, the preparation method of the plantain extract is as follows: take dried plantain, crush it, pass it through a 40-60 mesh sieve, add 8-12 times the amount of 50-70wt% ethanol aqueous solution, heat under reflux 2-3 times, each time for 1-2 hours, the extraction temperature is 45-55℃, combine the extracts, concentrate under reduced pressure at 60-70℃ to obtain a concentrated plantain extract, adsorb the concentrated extract through macroporous resin, elute with 50-70wt% ethanol, and spray dry the eluent to obtain the plantain extract.
[0026] The preparation method of the licorice extract is as follows: licorice is pulverized and sieved, 8-12 times the mass of 50-70wt% ethanol aqueous solution is added, and the mixture is heated and refluxed at 40-50℃ for 1-2 times. The extracts are combined, concentrated, and purified to obtain the licorice extract.
[0027] Preferably, the preparation method of the licorice extract is as follows: Take dried licorice, pulverize it, and pass it through a 40-60 mesh sieve. Add 8-12 times the amount of 50-70wt% ethanol aqueous solution, mix well, and then heat and ultrasonically extract 1-2 times, each time for 1-2 hours, generally at an extraction temperature of 40-50℃. Combine the extracts, filter and collect the clear extract, adjust the pH to 2-3, extract and concentrate with 1-2 times the amount of ethyl acetate to obtain the extract. Pass the concentrated extract through a macroporous resin, elute, collect the eluent, concentrate, and dry to obtain the licorice extract.
[0028] The preparation method of the Platycodon grandiflorus extract is as follows: Platycodon grandiflorus is crushed and sieved, 10-20 times the mass of 70-90wt% ethanol aqueous solution is added, and the mixture is heated and refluxed at 80-85℃ for 2-3 times. The extracts are combined, concentrated and purified to obtain the Platycodon grandiflorus extract.
[0029] Preferably, the preparation method of the Platycodon grandiflorus extract is as follows: Take dried Platycodon grandiflorus, pulverize it, and pass it through a 40-80 mesh sieve. Add 10-20 times the volume of 70-90wt% ethanol aqueous solution, mix evenly, and reflux at 80-85℃ for extraction 2-3 times, each time for 1-2 hours. Combine the extracts, add 0.5%-1% activated carbon, heat and reflux for decolorization for 0.5-2 hours, filter while hot, and concentrate under vacuum at 50-60℃ to obtain a concentrated Platycodon grandiflorus extract. Dilute the concentrated extract with distilled water to a solid content of 5%-10%, adjust the pH to 5-6, adsorb through macroporous resin, and elute with 50wt%-70wt% ethanol solution. Concentrate and dry the eluent to obtain the Platycodon grandiflorus extract.
[0030] Secondly, the present invention provides a method for preparing the above-mentioned plant extract multi-effect composition, comprising the following steps: mixing raw materials with a solvent to obtain the plant extract multi-effect composition.
[0031] The solvent is selected from at least one of 1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, 1,2-pentanediol, 1,5-pentanediol, isopentanediol, isohexanediol, 1,2-hexanediol, dipropylene glycol, water, glycerol, and methylpropanediol.
[0032] Preferably, the solvent is 1,3-butanediol.
[0033] Thirdly, the present invention provides the application of the above-described plant extract multi-effect composition in the preparation of cosmetics with anti-ultraviolet effects.
[0034] Preferably, the cosmetics include, but are not limited to, toners, serums, lotions, face creams, sunscreens, face masks, hand creams, whitening creams, skin-awakening lotions, soothing eye creams, antifreeze creams, lotions, perfumes, liquid foundations, foundation creams, concealers, blush, lipsticks, eyeshadows, or blushes.
[0035] The present invention has at least the following beneficial effects: This invention provides a multi-effect plant extract composition. Through a combination of specific plant extracts, especially European larch extract, plantain extract, and platycodon extract prepared by a specific preparation method, and their specific ratios, the anti-ultraviolet damage efficacy of the multi-effect plant extract composition is significantly improved, including significantly increased cell survival rate, higher DPPH free radical scavenging rate, and significantly reduced levels of inflammatory factors. Detailed Implementation
[0036] The following non-limiting embodiments are intended to enable those skilled in the art to gain a more comprehensive understanding of the present invention, but do not limit the invention in any way. The following content is merely an exemplary description of the scope of protection claimed by the present invention, and those skilled in the art can make various changes and modifications to the present invention based on the disclosed content, and such changes should also fall within the scope of protection claimed by the present invention.
[0037] The present invention will be further described below by way of specific embodiments. Unless otherwise specified, all instruments, devices, equipment, reagents, products, etc., used in the embodiments of the present invention are obtained through conventional commercial means.
[0038] Basic Example 1 Preparation of European larch extract: Take 55 kg of European larch wood, pulverize it using a traditional Chinese medicine pulverizer, and pass it through a 60-80 mesh sieve to obtain European larch wood powder. Take 50 kg of the sieved European larch wood powder, add 8-10 times the amount of 60-80% ethanol aqueous solution, mix well and soak for 1 hour. After soaking, heat and reflux 2-3 times at an extraction temperature of 50℃. Combine the extracts and concentrate them under reduced pressure at 65℃ to obtain a concentrated European larch wood extract. Pass the concentrated extract through a macroporous resin, elute with an eluent and collect the eluent. Recover the ethanol under reduced pressure to obtain a concentrated European larch wood extract. Disperse it with an appropriate amount of purified water, discard the supernatant, filter, and obtain a precipitate. Dry it under reduced pressure at 60℃ to obtain the European larch wood extract.
[0039] Basic Implementation Example 2 Preparation method of Plantago asiatica extract: Take dried Plantago asiatica, crush it, and pass it through a 40-60 mesh sieve. Add 8-12 times the amount of 50-70wt% ethanol aqueous solution, heat and reflux 2-3 times, 1-2 hours each time, and extract at 50℃. Combine the extracts and concentrate them under reduced pressure at 60-70℃ to obtain concentrated Plantago asiatica extract. Adsorb the concentrated extract through macroporous resin and elute with 50-70wt% ethanol. Spray dry the eluent to obtain Plantago asiatica extract.
[0040] Basic Example 3 Preparation method of licorice extract: Take dried licorice, pulverize it, and pass it through a 40-60 mesh sieve. Add 8-12 times the amount of 50-70wt% ethanol aqueous solution, mix well, and then heat and ultrasonically extract 1-2 times, 1-2 hours each time, generally at an extraction temperature of 40-50℃. Combine the extracts, filter and collect the clear extract, adjust the pH to 2-3, and extract and concentrate with 1-2 times the amount of ethyl acetate to obtain the extract. Pass the concentrated solution through a macroporous resin, elute, collect the eluent, concentrate, and dry to obtain the licorice extract.
[0041] Basic Example 4: Preparation method of Platycodon grandiflorus extract: Take dried Platycodon grandiflorus, pulverize it, and pass it through a 40-80 mesh sieve. Add 10-20 times the amount of 70-90wt% ethanol aqueous solution, mix well, and reflux at 80-85℃ for 2-3 times, 1-2 hours each time. Combine the extracts, add 0.5%-1% activated carbon, heat and reflux for decolorization for 0.5-2 hours, filter while hot, and concentrate under vacuum at 50-60℃ to obtain a concentrated Platycodon grandiflorus extract. Dilute the concentrated extract with distilled water to a solid content of 5%-10%, adjust the pH to 5-6, adsorb through macroporous resin, and elute with 50wt%-70wt% ethanol solution. Concentrate and dry the eluent to obtain the Platycodon grandiflorus extract.
[0042] Example 1 A plant extract multi-effect composition, by weight, comprises the following raw materials: 20 parts European larch extract, 10 parts plantain extract, 2 parts licorice extract and 1 part bellflower extract.
[0043] The preparation method is as follows: In a 250mL flask equipped with a thermometer and a stirrer, add the above raw materials and 1,3-butanediol (to a total of 100 parts), heat to 40°C, stir for 30-50 minutes until completely mixed, cool to room temperature, filter to remove insoluble impurities, and obtain the plant extract multi-effect composition.
[0044] Example 2 A plant extract multi-effect composition, comprising, by weight parts: 15 parts European larch extract, 15 parts plantain extract, 2 parts licorice extract and 1 part platycodon extract.
[0045] Example 3 A plant extract multi-effect composition, comprising the following raw materials in parts by weight: 20 parts European larch extract, 10 parts plantain extract, and 3 parts licorice extract.
[0046] The rest is the same as in Example 1.
[0047] Example 4 A plant extract multi-effect composition, comprising the following raw materials in parts by weight: 20 parts European larch extract, 10 parts plantain extract, and 3 parts bellflower extract.
[0048] The rest is the same as in Example 1.
[0049] Example 5 A plant extract multi-effect composition, comprising the following raw materials by weight: 15 parts European larch extract, 15 parts plantain extract, and 3 parts licorice extract.
[0050] The rest is the same as in Example 1.
[0051] Example 6 A plant extract multi-effect composition, comprising the following raw materials by weight: 15 parts European larch extract, 15 parts plantain extract, and 3 parts bellflower extract.
[0052] The rest is the same as in Example 1.
[0053] Comparative Example 1 A plant extract multi-effect composition, comprising, by weight, the following ingredients: 30 parts European larch extract, 2 parts licorice extract and 1 part bellflower extract.
[0054] The rest is the same as in Example 1.
[0055] Comparative Example 2 A plant extract multi-effect composition, comprising the following raw materials in parts by weight: 30 parts plantain extract, 2 parts licorice extract and 1 part platycodon extract.
[0056] The rest is the same as in Example 1.
[0057] Comparative Example 3 A plant extract multi-effect composition comprising, by weight, the following raw materials: 33 parts of European larch wood extract.
[0058] The rest is the same as in Example 1.
[0059] Comparative Example 4 A plant extract multi-effect composition, comprising the following raw materials by weight: 33 parts plantain extract.
[0060] The rest is the same as in Example 1.
[0061] Comparative Example 5 A plant extract multi-effect composition comprising, by weight, the following raw materials: 33 parts licorice extract.
[0062] The rest is the same as in Example 1.
[0063] Comparative Example 6 A plant extract multi-effect composition, comprising, by weight parts, the following raw materials: 33 parts of Platycodon grandiflorus extract.
[0064] The rest is the same as in Example 1.
[0065] Comparative Example 7 A plant extract multi-effect composition, comprising the following raw materials in parts by weight: 20 parts of neem extract, 10 parts of aloe extract, 2 parts of licorice extract and 1 part of platycodon extract.
[0066] The preparation methods of the extracts of *Melia azedarach* and aloe vera were as described in Example 1 of Chinese patent application CN108078878A, and the rest were the same as in Example 1.
[0067] Test Example 1 UVA damage resistance tests of different compositions: Test cells: Human immortalized keratinocytes (HaCaT) used in this experiment.
[0068] Cytotoxicity assay: Different concentrations of the composition were added to 96-well plates containing cells and incubated under suitable conditions for 24 hours. The cell viability was then determined using the CCK-8 assay to determine the safe concentration range for ≥90%. During the test, cell viability was ≥90% when the concentration of the test sample was less than 5 g / L.
[0069] UVA-induced cell damage viability assay: Human immortalized keratinocytes (HaCaT) in logarithmic growth phase were subjected to UVA-induced cell damage at a concentration of 1×10⁻⁶. 4 Cells were seeded at a density of 10 cells / mL in 96-well plates and incubated at 37°C, 5% CO2, 95% RH for 24 hours. After incubation, different concentrations of the test solution were added, with 6 replicates per group, and the plates were incubated for another 24 hours. The supernatant was discarded, and the cells were washed with PBS. PBS was then used instead of DMEM complete medium. The groups exposed to UVB (model control group, Examples 1-5, Comparative Examples 1-7) were subjected to UVB irradiation at 278 J / cm². 2 The cells were irradiated with UVA, and a blank control group (no UVA irradiation, no sample) was set up. After incubation in an incubator for 24 h, the cells were washed with PBS, DMEM complete medium and CCK-8 were added, and after incubation, the OD value was read at 450 nm. The relative cell viability was calculated according to formula (1): .
[0070] The cell survival rate results are shown in Table 1 below: Table 1
[0071] Note: Compared with the model control group, # P < 0.05 ## P < 0.01.
[0072] The data in Table 1 show that the mixture of larch extract and plantain extract has a highly significant effect against UV damage (p<0.01) and a significant synergistic effect against UV damage. Furthermore, the mixture of the two extracts has a significant synergistic effect against UV damage with licorice extract and platycodon extract.
[0073] Test Example 2 Antioxidant capacity test: Weigh 0.0025g of DPPH and dilute to 50mL with anhydrous ethanol to prepare a 0.05g / L DPPH solution for later use. Prepare a 5g / L sample test solution. Add 180μL of DPPH solution and 20μL of sample to a 96-well plate, shake well, and incubate at 25℃ for 30min. Measure the absorbance Ad at 517nm using an ELISA reader. Use anhydrous ethanol instead of DPPH solution to measure the absorbance Ac. Use anhydrous ethanol instead of the sample to measure the absorbance Ab. In addition, set a zeroing well to test the absorbance Aa of anhydrous ethanol. At the same time, use L-ascorbic acid as a positive control and measure according to the above method. Measure 3 replicates for each sample solution and calculate the clearance rate according to formula (2): ; In formula (2): Aa: Average absorbance of the solvent background pores; Ab: Average absorbance of the solvent reaction wells; Ac: Average absorbance of the sample bottom well; Ad: Absorbance of the sample bottom hole.
[0074] The results of DPPH free radical scavenging rate are shown in Table 2 below: Table 2
[0075] The results in Table 2 show that the antioxidant effects of the combination including European larch extract and plantain extract are better than those of using any one of the above components alone, indicating that the three or more components have a synergistic antioxidant effect.
[0076] Test Example 3 Effects of different compositions on the secretion of inflammatory cytokine (IL-6): Take RAW264.7 cells in the logarithmic growth phase into centrifuge tubes and adjust the cell concentration to 1×10⁻⁶. 5 Cells / mL were seeded into 24-well plates at a rate of 500 μL / well and cultured for 24 h in a 5% CO2, 37°C incubator. The experiment was divided into a blank control group, an LPS model group, a positive control group, and a sample group (Examples 1-5, Comparative Examples 1-7), with 3 replicates per group. After drug administration, the culture plates were placed at 37°C ± 1°C and CO2 concentration of 5% ± 1% for 24 h. At the end of the culture, the cell supernatant was collected, and the IL-6 content was determined according to the instructions of the enzyme-linked immunosorbent assay kit. The inhibition rate of IL-6 was calculated according to formula (3): ; In the formula: The average level of T-test substance inflammatory factors; The average content of inflammatory factors in the C-negative control group.
[0077] The IL-6 inhibition rate results are shown in Table 3 below: Table 3
[0078] As shown in Table 3, the combination of European larch extract and plantain extract showed better inhibition of the inflammatory factor IL-6 than either of the above components alone, indicating that the three or more components have a synergistic anti-inflammatory effect.
[0079] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, and is not intended to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions made by those skilled in the art to the technical solution of the present invention do not depart from the essence and scope of the technical solution of the present invention.
Claims
1. A multi-effect composition of plant extracts, characterized in that, It includes the following ingredients: European larch wood extract, plantain extract and plant extract A, wherein plant extract A is selected from at least one of licorice extract or bellflower extract.
2. The plant extract multi-effect composition according to claim 1, characterized in that, The mass ratio of the European larch extract to the plantain extract is (15-25):(5-15).
3. The plant extract multi-effect composition according to claim 1, characterized in that, It includes the following ingredients: European larch wood extract, plantain extract, licorice extract, and bellflower extract.
4. The plant extract multi-effect composition according to claim 3, characterized in that, The mass ratio of the European larch extract, plantain extract, licorice extract and platycodon extract is (15-25):(5-15):(1-5):(1-3).
5. The plant extract multi-effect composition according to claim 1, characterized in that, The preparation method of the European larch wood extract is as follows: European larch wood is crushed and sieved, 8-10 times the mass of 60-80wt% ethanol aqueous solution is added, and the mixture is heated and refluxed 2-3 times at an extraction temperature of 45-55℃. The extracts are combined, concentrated, and purified to obtain the European larch wood extract.
6. The plant extract multi-effect composition according to claim 1, characterized in that, The preparation method of the plantain extract is as follows: plantain is crushed and sieved, 8-12 times the mass of 50-70wt% ethanol aqueous solution is added, and the mixture is heated and refluxed 2-3 times at an extraction temperature of 45-55℃. The extracts are combined, concentrated, and purified to obtain the plantain extract.
7. The plant extract multi-effect composition according to claim 1, characterized in that, The preparation method of the licorice extract is as follows: licorice is pulverized and sieved, 8-12 times the mass of 50-70wt% ethanol aqueous solution is added, and the mixture is heated and refluxed at 40-50℃ for 1-2 times. The extracts are combined, concentrated, and purified to obtain the licorice extract.
8. The plant extract multi-effect composition according to claim 1, characterized in that, The preparation method of the Platycodon grandiflorus extract is as follows: Platycodon grandiflorus is crushed and sieved, and 10-20 times the mass of 70-90wt% ethanol aqueous solution is added. The mixture is heated and refluxed at 80-85℃ for 2-3 times. The extracts are combined, concentrated, and purified to obtain the Platycodon grandiflorus extract.
9. A method for preparing the plant extract multi-effect composition according to any one of claims 1-8, characterized in that, The process includes the following steps: mixing the raw materials with a solvent to obtain a multi-effect plant extract composition.
10. The use of the plant extract multi-effect composition according to any one of claims 1-8 in the preparation of cosmetics with anti-ultraviolet effects.
Citation Information
Patent Citations
Huang Xiang neem-aloe extract for preventing and treating propionibacterium acnes and application thereof
CN108078878A