Airtightness test device and method for cabin of biosafety laboratory
By combining a rectangular frame, sealing strips, and annular airbags, along with a digital micromanometer and thermo-hygrometer, the problem of detection deviation in the airtightness testing of biosafety laboratory cabins has been solved, achieving higher precision in airtightness monitoring and real-time temperature and humidity detection.
Patent Information
- Application Number
- CN202511717495.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-21
- Publication Date
- 2026-02-24
AI Technical Summary
Existing biosafety laboratory chamber airtightness testing technologies cannot effectively identify potential airtightness leakage risks, nor can they monitor the impact of temperature and humidity changes on airtightness in real time, leading to biased test results.
It adopts a combination of rectangular frame, sealing strip, annular airbag and clamping components, and improves detection accuracy through a double sealing structure. It also uses digital micromanometer and thermo-hygrometer to monitor pressure difference and temperature and humidity changes in real time.
It improves the accuracy of pressure difference detection inside and outside the cabin, enabling more precise identification of potential airtightness hazards and real-time monitoring of temperature and humidity changes to ensure the accuracy of detection results.
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Figure CN121558281A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of biosafety laboratory technology, specifically relating to a biosafety laboratory cabin airtightness testing device and method. Background Technology
[0002] The airtightness test of a biosafety laboratory chamber is a core component in ensuring the compliance of the laboratory's biosafety level and the safety of its operation. Its core function is to prevent the leakage of biological agents or the intrusion of external contaminants by testing the sealing performance of the chamber structure. Through the airtightness test, sealing defects in key parts such as chamber doors, windows, pipe interfaces through walls, wall joints, and joints between the floor and the wall can be identified in advance, ensuring that the chamber forms a sealed barrier and physically blocking the uncontrolled spread of biological agents.
[0003] However, because the laboratory cabin doors were tested using the normal installation method, some doors with actual airtightness problems could not be effectively identified, which concealed some potential airtightness leakage risks and increased the possibility of gas leakage during subsequent use.
[0004] Current detection technologies lack real-time temperature and humidity monitoring capabilities, making it impossible to detect the impact of temperature and humidity changes on airtightness and leakage in a timely manner. For example, when the temperature decreases by 0.1 degrees Celsius, the pressure decreases by approximately 34 Pa, but in actual testing, this pressure fluctuation caused by temperature changes cannot be captured, which may lead to deviations in the test results. Summary of the Invention
[0005] The purpose of this invention is to provide a device and method for testing the airtightness of a biosafety laboratory chamber, which can achieve a high degree of sealing at the door opening of the chamber, thereby increasing the accuracy of pressure difference detection inside and outside the chamber.
[0006] The specific technical solution adopted by this invention is as follows:
[0007] A biosafety laboratory chamber airtightness testing device includes a rectangular frame, with sealing strips fixedly connected to the sides of the rectangular frame, the sealing strips forming a ring structure around the rectangular frame, and at least ten clamping components provided on the side wall of the rectangular frame.
[0008] An annular airbag is fixedly connected to the rear side wall of the sealing strip. Several partitions are fixedly connected at equal intervals to the inner wall of the annular airbag. Each partition has a through hole on its side wall. The partitions divide the annular airbag into several expansion points. A filling medium can be injected into the annular airbag.
[0009] The annular airbag is equipped with a heating element, and the front sidewall of the sealing strip is equipped with a medium filling and injection assembly.
[0010] It also includes digital micromanometers and thermo-hygrometers;
[0011] The digital micromanometer is used to detect and record the pressure difference between the inside and outside of the chamber;
[0012] The thermometer and hygrometer are used to record the cabin temperature and humidity.
[0013] Furthermore, the clamping assembly includes a pressure plate disposed on the side wall of the rectangular frame. The pressure plate has an L-shaped structure, and each side wall of the pressure plate is threaded with an adjusting bolt. The adjusting bolt passes through the pressure plate and is threadedly connected to the rectangular frame.
[0014] Furthermore, the heating element includes a heating wire, an installation hole is provided in the middle of the side wall of the partition, the heating wire is disposed in the installation hole, and a power supply connector is provided on the side wall of the sealing strip, the power supply connector being electrically connected to the heating wire.
[0015] Furthermore, the surface of the heating wire is coated with a heat-conducting layer.
[0016] Furthermore, the medium filling injection assembly includes an injection tube that communicates with the inner cavity of the annular airbag, and a first valve is installed on the side wall of the injection tube.
[0017] Furthermore, an inflation tube is fixedly connected to the front side wall of the sealing strip, the inflation tube is connected to the annular airbag, and a second valve is installed on the side wall of the inflation tube.
[0018] Furthermore, a pressure gauge is installed on the side wall of the inflation tube.
[0019] Furthermore, the material of the annular airbag is either silicone rubber or fluororubber.
[0020] Furthermore, the medium filling the annular airbag is wax.
[0021] A test method for a biosafety laboratory cabin airtightness testing device includes the following steps:
[0022] S1: The testers used the laboratory air duct inspection port, and after preparing the testing equipment and ensuring that the equipment was operating normally, they used an air compressor to pressurize the chamber, and at the same time used a digital micromanometer to record the pressure difference between the inside and outside of the chamber to obtain the initial pressure difference data.
[0023] S2: Place a thermometer and a hygrometer inside and outside the cabin to obtain initial temperature and humidity data;
[0024] S3: The testers used a rectangular frame and sealing strips to seal the door, and at the same time closed and secured all doors, pass-through windows, valves and airtight valves inside the cabin structure to keep the cabin in a closed state.
[0025] S4: Turn on the vacuum pump and slowly fill the chamber with air. At the same time, adjust the air inlet valve and use the digital micromanometer to record the pressure difference between the inside and outside of the chamber. When the pressure difference between the inside and outside of the chamber reaches more than 550pa, close the valve and obtain the high pressure difference data.
[0026] S5: The tester connects to the thermometer and hygrometer via a mobile app to observe the temperature data inside and outside the chamber. When the digital micro-pressure count reaches 500pa, the electronic stopwatch is used to start recording. The pressure difference and temperature are recorded every 30 seconds for at least 20 minutes to obtain a series of pressure difference and temperature change data.
[0027] S6: Disconnect the vacuum pump, slowly open the valve to restore the chamber pressure to normal, and complete one test;
[0028] S7: If a repeat test is required, repeat the above steps after 20 minutes to complete the cabin airtightness test process.
[0029] The technical effects achieved by this invention are as follows:
[0030] The present invention discloses a biosafety laboratory chamber airtightness testing device. Through the cooperation of a rectangular frame, sealing strips, annular airbags, a compression assembly, and a medium filling and injection assembly, the sealing strips are pressed tightly against the door opening by the compression assembly to perform a primary seal. Pressurized gas is injected into the annular airbag to fill multiple expansion points in the door opening gap. Medium wax is then injected into the annular airbag. After the wax solidifies, it fills the door opening gap for a secondary seal. This double sealing structure is used to improve the accuracy of pressure difference detection inside and outside the chamber. Attached Figure Description
[0031] Figure 1 This is a schematic diagram of the structure of the present invention;
[0032] Figure 2 This is a schematic diagram of the rear view structure of the present invention;
[0033] Figure 3 This is a rear cross-sectional view of the present invention;
[0034] Figure 4 This is a schematic diagram of the cross-sectional structure of the heating wire of the present invention;
[0035] Figure 5 This is a schematic diagram of the structure of the partition of the present invention;
[0036] Figure 6 This is the invention Figure 1 Enlarged view of point A in the image;
[0037] Figure 7 This is the invention Figure 3 Enlarged view of point B in the image.
[0038] The attached diagram lists the components represented by each number as follows:
[0039] 1. Rectangular frame; 2. Sealing strip; 3. Pressure plate; 4. Adjusting bolt; 5. Annular airbag; 6. Partition plate; 7. Through hole; 8. Heating wire; 9. Mounting hole; 10. Heat-conducting layer; 11. Injection pipe; 12. First valve; 13. Inflation pipe; 14. Second valve; 15. Pressure gauge; 16. Power supply connector. Detailed Implementation
[0040] To make the objectives and advantages of this invention clearer, the invention will be specifically described below with reference to embodiments. It should be understood that the following text is merely used to describe one or more specific embodiments of the invention and does not strictly limit the scope of protection specifically claimed by the invention.
[0041] Example 1:
[0042] like Figures 1-7 As shown, a biosafety laboratory cabin airtightness testing device includes a rectangular frame 1, with sealing strips 2 fixedly connected to the side of the rectangular frame 1. The sealing strips 2 form a ring structure around the rectangular frame 1, and at least ten clamping components are provided on the side wall of the rectangular frame 1.
[0043] The sealing strip 2 is installed around the perimeter of the rectangular frame 1. It is made of highly elastic, aging-resistant rubber material, ensuring that the sealing strip 2 maintains good sealing performance even after repeated compression and stretching during long-term use. The sealing strip 2 is elongated, with a cross-sectional shape that is mostly circular or square, to better fill the gap between the rectangular frame 1 and the door opening. The sealing strip 2 is adhered to the perimeter of the rectangular frame 1; this installation method not only firmly fixes the sealing strip 2 to the frame, preventing it from falling off, but also facilitates future replacement of the strip.
[0044] An annular airbag 5 is fixedly connected to the rear side wall of the sealing strip 2. Several partitions 6 are fixedly connected at equal intervals to the inner wall of the annular airbag 5. Each partition 6 has a through hole 7 on its side wall. The partitions 6 divide the annular airbag 5 into several expansion points. A filling medium can be injected into the annular airbag 5. The filling medium in the annular airbag 5 is wax.
[0045] The material of the ring-shaped airbag 5 can be either silicone rubber or fluororubber.
[0046] Specifically, the melting point of wax is 50-70℃, while the material used in the annular airbag 5 has high temperature resistance, ensuring that the long-term temperature resistance is higher than the melting temperature of wax, with a safety margin of 20-30℃. For example, if the melting point of wax is 70℃, the temperature resistance of the annular airbag 5 needs to be ≥90℃.
[0047] Furthermore, before actual application, a compatibility test is conducted in advance by immersing the annular airbag material 5 in molten wax (24-48 hours) to observe whether aging phenomena such as swelling, discoloration, and decreased hardness occur, so as to avoid the wax components (such as oily additives) from damaging the rubber structure.
[0048] like Figure 3 , Figure 4 and Figure 7 As shown, a heating element is provided in the inner cavity of the annular airbag 5, and a medium filling injection assembly is provided on the front side wall of the sealing strip 2;
[0049] The heating element includes a heating wire 8. A mounting hole 9 is provided in the middle of the side wall of the partition plate 6. The heating wire 8 is placed in the mounting hole 9. A power supply connector 16 is provided on the side wall of the sealing strip 2. The power supply connector 16 is electrically connected to the heating wire 8.
[0050] The surface of the heating wire 8 is covered with a heat-conducting layer 10.
[0051] When the rectangular frame 1 and the annular airbag 5 need to be reset later, an external power supply can be connected through the power supply connector 16 to supply power to the heating wire 8. The temperature range of the heating wire 8 is 50-80℃, which is used to melt the solidified wax, so that the wax can be discharged in a liquid state. At the same time, the annular airbag 5 loses pressure and resets, making it convenient to remove the whole unit for inspection and maintenance.
[0052] It also includes digital micromanometers and thermo-hygrometers;
[0053] Digital micromanometers are used to detect and record the pressure difference between the inside and outside of the chamber;
[0054] The thermometer and hygrometer are used to record the temperature and humidity of the cabin.
[0055] Among them, the digital manometer adopts the TSI-5825 digital manometer imported from the United States; the temperature and humidity meter adopts the Jiali wireless Bluetooth waterproof temperature and humidity meter, and the Jiali wireless Bluetooth waterproof temperature and humidity meter can be connected to the collection app to realize wireless data transmission and view the changes in temperature and humidity data in real time.
[0056] Thanks to a precise and standardized testing process, and the use of a high-precision American-imported TSI-5825 digital micromanometer and a Jiali wireless Bluetooth waterproof thermometer and hygrometer, the pressure difference and temperature / humidity data of the cabin can be obtained more accurately. Traditional methods, due to insufficient precision in the testing process and equipment accuracy, struggle to accurately capture these crucial data, leading to biased judgments about cabin airtightness. This invention, through the aforementioned improvements, effectively enhances the ability to identify cabin airtightness problems and can more accurately detect potential airtightness hazards.
[0057] like Figure 1 and Figure 6As shown, the clamping assembly includes a pressure plate 3 disposed on the side wall of the rectangular frame 1. The pressure plate 3 has an L-shaped structure, and adjusting bolts 4 are threadedly connected to the side wall of the pressure plate 3. The adjusting bolts 4 pass through the pressure plate 3 and are threadedly connected to the rectangular frame 1.
[0058] Specifically, during installation, the sealing strip 2 is attached to the door opening, and the adjusting bolt 4 is tightened in sequence using a wrench. The adjusting bolt 4 moves the pressure plate 3, and the pressure plate 3 applies pressure to the sealing strip 2, so that the sealing strip 2 can be tightly attached to the door opening, sealing small gaps, improving sealing performance, and thus ensuring test accuracy.
[0059] like Figure 6 As shown, the medium filling and injection assembly includes an injection tube 11, which is connected to the inner cavity of the annular airbag 5, and a first valve 12 is installed on the side wall of the injection tube 11.
[0060] An inflation tube 13 is fixedly connected to the front side wall of the sealing strip 2. The inflation tube 13 is connected to the annular airbag 5. A second valve 14 is installed on the side wall of the inflation tube 13.
[0061] A pressure gauge 15 is installed on the side wall of the inflation pipe 13.
[0062] When long-term sealing of the hatch is required, an external pressure pump is connected to the injection pipe 11, and molten wax is injected into the injection pipe 11 through the pressure pump. This allows the liquid wax to enter the annular airbag 5, and the pressure of the injected liquid wax causes the annular airbag 5 to expand at specific points, filling the small gaps in the doorway. At the same time, the surface of the annular airbag 5 adheres to the gaps in the doorway, achieving a seal. After filling is complete, the first valve 12 is closed, the pressure pump is disconnected, and any remaining liquid wax in the pressure pump is cleaned out. Once the liquid wax in the annular airbag 5 solidifies, it adapts to the contour of the doorway gaps, achieving an adaptive filling and sealing effect.
[0063] When a temporary seal is required on the hatch, the inflation pipe 13 is connected to an external high-pressure gas, the second valve 14 is opened, and the high-pressure gas is injected into the annular airbag 5. The high-pressure gas causes the annular airbag 5 to expand at specific points and fill the gap in the door opening, thus achieving an adaptive filling and sealing effect. This ensures that the inside and outside of the cabin are in a sealed and isolated state during the test, thereby improving the sealing effect and test accuracy.
[0064] Example 2:
[0065] A test method for a biosafety laboratory cabin airtightness testing device includes the following steps:
[0066] S1: The testers used the laboratory air duct inspection port, and after preparing the testing equipment and ensuring that the equipment was operating normally, they used an air compressor to pressurize the chamber, and at the same time used a digital micromanometer to record the pressure difference between the inside and outside of the chamber to obtain the initial pressure difference data.
[0067] S2: Place a thermometer and a hygrometer inside and outside the cabin to obtain initial temperature and humidity data;
[0068] S3: The testers used rectangular frame 1 and sealing strip 2 to seal the door, and at the same time closed and firmly fixed all doors, pass-through windows, valves and airtight valves in the cabin structure to keep the cabin in a closed state.
[0069] S4: Turn on the vacuum pump and slowly fill the chamber with air. At the same time, adjust the air inlet valve and use the digital micromanometer to record the pressure difference between the inside and outside of the chamber. When the pressure difference between the inside and outside of the chamber reaches more than 550pa, close the valve and obtain the high pressure difference data.
[0070] S5: The tester connects to the thermometer and hygrometer via a mobile app to observe the temperature data inside and outside the chamber. When the digital micro-pressure count reaches 500pa, the electronic stopwatch is used to start recording. The pressure difference and temperature are recorded every 30 seconds for at least 20 minutes to obtain a series of pressure difference and temperature change data.
[0071] S6: Disconnect the vacuum pump, slowly open the valve to restore the chamber pressure to normal, and complete one test;
[0072] S7: If a repeat test is required, repeat the above steps after 20 minutes to complete the cabin airtightness test process.
[0073] During the testing process, if any abnormalities are found, such as a sharp drop in pressure as indicated by the manometer, abnormal fluctuations in temperature and humidity data, or equipment malfunction (e.g., garbled characters on the manometer display, disconnection of the temperature and humidity meter), the testing should be stopped immediately. For areas using special sealing methods (such as Boeing cloth adhesive sealing or aluminum plate sealing), the sealing effect of these areas should be checked immediately to ensure the sealing material is tightly adhered and undamaged, ensuring a good seal and avoiding affecting the test results. After identifying and resolving the problem, testing can continue. If a poor seal is found in a certain area of the sealing device during the testing process, such as a loose seal at the upper left corner frame, the tester should use a wrench to rotate the adjusting bolt 4 on the frame appropriately, further pressing the sealing strip 2 with the pressure plate 3 to enhance the sealing effect at that location. Afterward, continue to observe the test data to ensure the accuracy and reliability of the test results.
[0074] The above description is merely a preferred embodiment of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention. Structures, devices, and operating methods not specifically described or explained in this invention are implemented according to conventional methods in the art unless otherwise specified or limited.
Claims
1. A biosafety laboratory chamber airtightness testing device, characterized in that: Includes a rectangular frame (1), with a sealing strip (2) fixedly connected to the side of the rectangular frame (1), the sealing strip (2) forming a ring structure around the rectangular frame (1), and at least ten clamping components provided on the side wall of the rectangular frame (1); The sealing strip (2) is fixedly connected to the rear side wall of an annular airbag (5). Several partitions (6) are fixedly connected at equal intervals on the inner wall of the annular airbag (5). The side walls of the partitions (6) are provided with through holes (7). The partitions (6) divide the annular airbag (5) into several expansion points. The annular airbag (5) can be filled with a filling medium. The annular airbag (5) is provided with a heating element in its inner cavity, and the sealing strip (2) is provided with a medium filling injection assembly on its front side wall; It also includes digital micromanometers and thermometers and hygrometers; The digital micromanometer is used to detect and record the pressure difference between the inside and outside of the chamber; The thermometer and hygrometer are used to record the cabin temperature and humidity.
2. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: The clamping assembly includes a pressure plate (3) disposed on the side wall of the rectangular frame (1). The pressure plate (3) has an L-shaped structure. The side wall of the pressure plate (3) is threaded with adjusting bolts (4). The adjusting bolts (4) pass through the pressure plate (3) and are threadedly connected to the rectangular frame (1).
3. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: The heating element includes a heating wire (8), and an installation hole (9) is provided in the middle of the side wall of the partition (6). The heating wire (8) is placed in the installation hole (9), and a power supply connector (16) is provided on the side wall of the sealing strip (2). The power supply connector (16) is electrically connected to the heating wire (8).
4. The biosafety laboratory chamber airtightness testing device according to claim 3, characterized in that: The heating wire (8) is covered with a heat-conducting layer (10).
5. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: The medium filling and injection assembly includes an injection tube (11) that is connected to the inner cavity of the annular airbag (5) and a first valve (12) is installed on the side wall of the injection tube (11).
6. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: An inflation tube (13) is fixedly connected to the front side wall of the sealing strip (2). The inflation tube (13) is connected to the annular airbag (5). A second valve (14) is installed on the side wall of the inflation tube (13).
7. The biosafety laboratory chamber airtightness testing device according to claim 6, characterized in that: A pressure gauge (15) is installed on the side wall of the inflation tube (13).
8. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: The material of the annular airbag (5) is either silicone rubber or fluororubber.
9. The biosafety laboratory chamber airtightness testing device according to claim 1, characterized in that: The annular airbag (5) is filled with wax as the medium.
10. A test method for a biosafety laboratory cabin airtightness testing device, comprising the biosafety laboratory cabin airtightness testing device according to any one of claims 1-9, characterized in that: Includes the following steps: S1: The testers used the laboratory air duct inspection port, and after preparing the testing equipment and ensuring that the equipment was operating normally, they used an air compressor to pressurize the chamber, and at the same time used a digital micromanometer to record the pressure difference between the inside and outside of the chamber to obtain the initial pressure difference data. S2: Place a thermometer and a hygrometer inside and outside the cabin to obtain initial temperature and humidity data; S3: The testers used a rectangular frame (1) and sealing strips (2) to seal the door, and at the same time closed and fixed all doors, pass-through windows, valves and airtight valves in the cabin structure to keep the cabin in a closed state. S4: Turn on the vacuum pump and slowly fill the chamber with air. At the same time, adjust the air inlet valve and use the digital micromanometer to record the pressure difference between the inside and outside of the chamber. When the pressure difference between the inside and outside of the chamber reaches more than 550pa, close the valve and obtain the high pressure difference data. S5: The tester connects to the thermometer and hygrometer via a mobile app to observe the temperature data inside and outside the chamber. When the digital micro-pressure count reaches 500pa, the electronic stopwatch is used to start recording. The pressure difference and temperature are recorded every 30 seconds for at least 20 minutes to obtain a series of pressure difference and temperature change data. S6: Disconnect the vacuum pump, slowly open the valve to restore the chamber pressure to normal, and complete one test; S7: If a repeat test is required, repeat the above steps after 20 minutes to complete the cabin airtightness test process.