Preparation method of feed-grade coated pancreatin with high temperature resistance and acid resistance

By using a single-layer coating technology and enzyme pellet cores and coating materials with specific compositions, the problem of easy loss of enzyme activity in pancreatic enzymes under high temperature and high humidity conditions has been solved. This has resulted in pancreatic enzyme coatings with high temperature and acid resistance, improved enzyme activity retention rate, and simplified the process.

CN121587360APending Publication Date: 2026-03-03SHANGHAI HONEST BIOLOGICAL TECH CO LTD +2
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Patent Information

Application Number
CN202610051047.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-01-15
Publication Date
2026-03-03

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Abstract

The invention discloses a preparation method of feed-grade coated pancreatin with high temperature resistance and acid resistance, the feed-grade coated pancreatin comprises an enzyme-containing pellet core and a coating layer, and the enzyme-containing pellet core is composed of pancreatin, sodium sulfate, microcrystalline cellulose, kaolin and starch; and the coating layer consists of mono / diglycerol fatty acid ester, hydrogenated palm oil and calcium carbonate. The particle size of the coated pancreatin ranges from 20 meshes to 60 meshes, and the particle size is uniform; compared with uncoated pancreatin powder, the pancreatin coated with the coating material has the advantages that the enzyme activity retention rate can be increased from 36.73% to 73.34% when the pancreatin is treated at 80 DEG C for 5 min, and the enzyme activity retention rate can be increased from 0.72% to 86.92% when the pancreatin is treated at pH 2.5 for 2 h. The coated pancreatin provided by the invention reduces the influence of high temperature on enzyme activity in the granulation process of poultry feed, reduces the damage of gastric juice to enzyme when poultry ingest, and can effectively improve the utilization rate of feed enzyme.
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Citation Information

Patent Citations

  • Complex enzyme coated pellet and preparation method thereof

    CN105265756A

  • High-temperature-resistant and acid-resistant pancreatin pellet as well as preparation method and application thereof

    CN117256739A