Precise-positioning bone marrow biopsy sampling device

Abstract

The invention relates to the technical field of medical apparatus and instruments, in particular to an accurate-positioning bone marrow biopsy sampling instrument which comprises a needle sleeve and a needle core. And a deformable drill bit is arranged at the far end of the needle core. When the drill bit at the far end of the needle core extends out of the needle sleeve and is in an unfolded state, the outer diameter of the drill bit is consistent with that of the needle sleeve, the hole diameter formed by drilling is matched with the outer diameter of the needle sleeve, hole diameter resistance during needle sleeve drilling is eliminated, and drilling difficulty of the needle sleeve is avoided; when the needle core drives the drill bit to retract into the needle sleeve and the drill bit is in a closed state, the outer wall of the drill bit is in sealing contact with the inner wall of the needle sleeve. At the moment, the needle sleeve can move relative to the needle core and drill into the bone marrow. Due to the sealing contact after the drill bit is closed, when the instrument is pulled out after sampling is completed, a sample can slide in the needle sleeve to generate negative pressure, bone marrow tissue is adsorbed, and the sample is prevented from falling off.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a precisely positioned bone marrow biopsy sampling device. Background Technology

[0002] Bone marrow biopsy sampling instruments are specialized medical devices used to collect bone marrow tissue samples. They are used to obtain intact bone marrow tissue blocks to aid in the diagnosis of hematological diseases, assessment of bone marrow hematopoietic function, and monitoring of treatment effectiveness. The instrument includes components such as a needle sheath, needle core, and a limiter. In use, the needle core is first inserted into the needle sheath, and a hole is drilled to the appropriate depth at the puncture site. After removing the needle core, the limiter is placed on to fix the sampling length. The needle core is then inserted again, and the needle sheath is rotated. The cutting edge at the front of the needle sheath cuts and wraps around the bone marrow tissue. Finally, the entire instrument is removed, completing the sample collection.

[0003] However, in existing technologies, the needle core diameter is smaller than the needle sheath diameter, resulting in a hole formed by the needle core penetrating the bone cortex that is slightly smaller than the needle sheath hole diameter. When the needle sheath drills in, the friction between the needle sheath and the bone cortex intensifies, which not only increases the difficulty of operation and the labor intensity of medical staff, but may also cause the needle sheath to deform due to excessive resistance, and even affect the integrity of the bone marrow tissue sample, thereby interfering with subsequent test results. Summary of the Invention

[0004] Therefore, it is necessary to provide a more precise bone marrow biopsy sampling device to address the problem that the diameter of the needle core hole in current bone marrow biopsy sampling devices is slightly smaller than the diameter of the needle sheath hole, which makes it difficult to drill the needle sheath.

[0005] The above objectives are achieved through the following technical solutions: A precise bone marrow biopsy sampling device, comprising: A needle sheath, used for drilling into the bone marrow and taking samples.

[0006] The needle core is movably disposed inside the needle sheath. A deformable drill bit is disposed at the distal end of the needle core. The drill bit has an unfolded state for drilling and a closed state for sealing contact with the inner wall of the needle sheath. When the drill bit is in the unfolded state, the outer diameter of the drill bit is equal to the outer diameter of the needle sheath. When the drill bit is in the closed state, the needle sheath can move relative to the needle core to drill into the bone marrow.

[0007] A drive assembly that can drive the needle core to retract the drill bit into the needle sleeve, so that the drill bit switches from the unfolded state to the closed state.

[0008] Furthermore, the drive assembly includes a fixed block and a rotating block. The fixed block is fixedly connected to the needle sleeve and is connected to the needle core via a threaded section. The rotating block is fixedly connected to the needle core, and the needle core is driven to move axially relative to the fixed block by rotating the rotating block. When the drill bit is in the closed state, the threaded section disengages from the fixed block.

[0009] Furthermore, it also includes a limiting component for controlling the drilling depth of the needle sleeve.

[0010] Furthermore, the limiting component includes an adjusting rod, a sliding sleeve, and a locking unit. The adjusting rod is connected to the needle core and can move synchronously with the needle core along the axial direction of the needle sleeve. The sliding sleeve is connected to the adjusting rod. When the needle sleeve penetrates the bone marrow, the locking unit can fix the relative position of the sliding sleeve and the skin to limit the penetration depth of the needle sleeve through the sliding sleeve.

[0011] Furthermore, an adjustment structure is provided between the adjusting rod and the sliding sleeve. The adjustment structure is used to adjust the position of the sliding sleeve on the adjusting rod to adjust the drilling depth of the needle sleeve.

[0012] Furthermore, the adjustment structure includes a slot and a block. The slot is disposed on the adjustment rod. Multiple blocks are disposed on the sliding sleeve, and each block can be embedded in the slot to fix the relative position of the sliding sleeve and the adjustment rod.

[0013] Furthermore, the locking unit includes a locking cylinder and a one-way structure. The locking cylinder is sleeved outside the sliding sleeve and can slide relative to the sliding sleeve. The one-way structure allows the locking cylinder to move on the sliding sleeve towards the skin and restricts its reverse movement.

[0014] Furthermore, the unidirectional structure is provided with multiple elastic plates and multiple inclined blocks. The elastic plates are disposed on the inner wall of the locking cylinder, and the inclined blocks are disposed on the outer wall of the sliding sleeve. When the locking cylinder moves toward the skin on the sliding sleeve, the inclined blocks can pass over the elastic plates. When the locking cylinder has a tendency to move in the opposite direction on the sliding sleeve, the elastic plates and the inclined blocks engage.

[0015] Furthermore, the locking cylinder includes at least two adjacent flaps, and all of the flaps are capable of radial movement along the sliding sleeve, so that the elastic sheet can disengage from the inclined block.

[0016] Furthermore, a reset elastic element is provided between adjacent valve bodies, and the elastic force of the reset elastic element is used to make the adjacent valve bodies fit together.

[0017] The beneficial effects of this invention are: This invention provides a precise bone marrow biopsy sampling device, comprising a needle sheath, a needle core, and a drive assembly. The needle core is movably disposed inside the needle sheath, and a deformable drill bit is disposed at the distal end of the needle core. The drill bit has an extended state and a retracted state. When drilling is required, the drill bit is in the extended state, at which time the outer diameter of the drill bit is consistent with the outer diameter of the needle sheath. The diameter of the hole formed during the drilling process is perfectly matched with the outer diameter of the needle sheath, eliminating the drilling resistance of the needle sheath caused by the small hole diameter and avoiding drilling difficulties caused by the mismatch in hole diameter, ensuring smooth subsequent drilling of the needle sheath. After drilling is completed, the drive assembly drives the needle core to retract the drill bit into the needle sheath, switching the drill bit from the extended state to the retracted state. In the retracted state, the drill bit forms a sealed contact with the inner wall of the needle sheath, providing a closed sampling environment for the needle sheath to move relative to the needle core and drill into the bone marrow, ensuring the stability of the sampling process and the integrity of the sample. Attached Figure Description

[0018] Figure 1 A schematic diagram of the structure of a precisely positioned bone marrow biopsy sampling device provided in an embodiment of the present invention; Figure 2 for Figure 1 A cross-sectional view of the drill bit of a precise bone marrow biopsy sampling instrument in the deployed state; Figure 3 for Figure 1 A cross-sectional view of a precision bone marrow biopsy sampling instrument with the drill bit in the closed position. Figure 4 for Figure 1 A cross-sectional view of the locking cylinder of a precise bone marrow biopsy sampling instrument when it is in contact with the skin; Figure 5 for Figure 1 A cross-sectional view of the needle sheath of a precise bone marrow biopsy sampling instrument during the sampling process. Figure 6 for Figure 2 A cross-sectional view along the AA direction; Figure 7 for Figure 2 A magnified view of a section at point B in the middle; Figure 8 for Figure 2 A magnified view of a section at point C; Figure 9 for Figure 3 A magnified view of a section at point D; Figure 10 for Figure 3 A magnified view of a section at point E in the middle; Figure 11 for Figure 4 A magnified view of a section at point F in the middle; Figure 12 for Figure 5 A magnified view of a section at point G in the middle; Figure 13 for Figure 5 A magnified view of a section at point H in the middle; Figure 14 for Figure 6 A magnified view of a section at point I; Figure 15 for Figure 7 A magnified view of a section at point J; Figure 16 A schematic diagram of the adjusting rod and sliding sleeve in a precise positioning bone marrow biopsy sampling device provided in an embodiment of the present invention; Figure 17 This is a schematic diagram of the needle core in a bone marrow biopsy sampling instrument for precise positioning provided in an embodiment of the present invention.

[0019] in: 110. Handle; 111. Fixing block; 120. Needle sleeve; 130. Needle core; 131. Drill bit; 132. First external thread; 133. Limiting groove; 140. Rotating block; 150. Adjusting rod; 151. Slot; 160. Sliding sleeve; 161. Locking block; 162. Inclined block; 170. Locking cylinder; 171. Elastic sheet; 172. Elastic connecting rope. Detailed Implementation

[0020] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below through embodiments and in conjunction with the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0021] The component designations used in this document, such as "first" and "second," are merely for distinguishing the described objects and do not have any sequential or technical meaning. The terms "connection" and "linkage" used in this invention, unless otherwise specified, include both direct and indirect connections (linkages). It should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are used only for the convenience of describing the invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as limiting the invention.

[0022] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "over," and "on top" of the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0023] The following reference Figures 1 to 17 This invention describes a precise bone marrow biopsy sampling device, comprising a handle 110, a needle sheath 120, a needle core 130, and a drive assembly.

[0024] The handle 110 is a grip structure to ensure stability of the grip and efficiency of driving force transmission during sampling. A cylindrical connecting tube extends axially downward from the lower end face of the handle 110.

[0025] The needle sheath 120 is a hollow, thin-walled cylindrical structure, with its upper end threadedly connected to the lower end of the connecting cylinder of the handle 110. The lower end of the needle sheath 120 serves as the sampling inlet, used for direct contact with the bone cortex and cutting bone marrow tissue. The hollow cavity at the lower end of the needle sheath 120 provides space to accommodate bone marrow tissue.

[0026] The needle core 130 is a solid cylindrical structure that can penetrate the needle sleeve 120 and move axially along the hollow cavity of the needle sleeve 120. A drill bit 131 is fixedly mounted at the lower end of the needle core 130. The drill bit 131 is a multi-lobed deformable structure, comprising multiple arc-shaped cutting lobes. The upper sidewalls of the cutting lobes and the lower end of the needle sleeve 120 are both provided with matching conical inclined surfaces, allowing them to tightly abut against each other. The drill bit 131 has an unfolded state where the multiple cutting lobes are separated and a closed state where adjacent cutting lobes are completely fitted together.

[0027] The needle core 130 has a first position and a second position, corresponding to the unfolded and closed states of the drill bit 131, respectively. When the needle core 130 is in the first position, the multiple cutting flaps of the drill bit 131 are fully extended from the lower end port of the needle sleeve 120 and separated from each other. At this time, the drill bit 131 is in the unfolded state, and the upper sidewall of the cutting flaps is in close contact with the lower end of the needle sleeve 120 through the tapered inclined surface. At the same time, the maximum outer diameter of the cutting flaps of the drill bit 131 is exactly equal to the outer diameter of the needle sleeve 120, which can form a hole diameter consistent with the outer diameter of the needle sleeve 120, eliminating the hole diameter resistance of the needle sleeve 120 during subsequent drilling. This eliminates the need for the needle sleeve 120 to overcome additional friction between the cortex and the outer wall of the needle sleeve 120 during subsequent drilling, significantly reducing the drilling resistance of the needle sleeve 120. Furthermore, during drilling, the cutting edge of the cutting flap can directly contact the cortex, increasing the cutting contact area during drilling and effectively reducing the resistance of drilling the cortex.

[0028] When the needle core 130 is in the second position, the cutting flap of the drill bit 131 is completely retracted into the hollow cavity of the needle sleeve 120, and the adjacent cutting flaps are completely in contact. At this time, the drill bit 131 is in the closed state, and the outer wall of the cutting flap of the drill bit 131 is in close contact with the inner wall of the needle sleeve 120, forming a completely sealed sampling cavity, which completely isolates the inside of the needle sleeve 120 from the outside world.

[0029] The drive assembly includes a rotating block 140 and a fixed block 111. The rotating block 140 is an annular block structure, and its inner hole is detachably connected to the upper end of the needle core 130 via a thread. The fixed block 111 is an internally threaded block structure, fixedly installed inside the handle 110. The outer wall of the needle core 130 is provided with a first external thread 132, and the inner hole of the fixed block 111 is provided with a first internal thread. The fixed block 111 achieves threaded transmission by engaging with the first external thread 132 of the needle core 130 through the first internal thread.

[0030] In the initial state, the needle core 130 is in the first position, and the multiple cutting flaps of the drill bit 131 are separated and unfolded. Rotating the handle 110 drives the needle core 130 to perform a drilling operation, forming a hole with the same diameter as the needle sleeve 120. After drilling is completed, rotating the rotating block 140 transmits the torque to the needle core 130. Under the threaded transmission between the fixed block 111 and the needle core 130, the needle core 130 moves upward axially. During this process, the cutting flaps of the drill bit 131 slide relative to the tapered inclined surface of the needle sleeve 120. Guided by the tapered inclined surface, the multiple cutting flaps of the drill bit 131 gradually approach each other. When the needle core 130 moves to the second position inside the needle sleeve 120, the first external thread 132 of the needle core 130 completely disengages from the first internal thread of the fixing block 111. The needle sleeve 120 can then move axially relative to the needle core 130. The cutting edge of the drill bit 131 is completely retracted into the needle sleeve 120, and its outer wall is completely sealed to the inner wall of the needle sleeve 120. Subsequently, the needle sleeve 120 moves along the outer wall of the needle core 130 to drill into the bone marrow, allowing bone marrow tissue to enter the hollow cavity of the needle sleeve 120. After sampling is completed, the entire sampling device is removed, and the rotating block 140 is screwed on to allow the needle core 130 to push the sample out of the needle sleeve 120, thus obtaining the sample.

[0031] Specifically, when the sampling device is removed, the drill bit 131 is in the closed state, and the outer wall of its cutting flap tightly abuts against the inner wall of the needle sheath 120, forming a completely sealed sampling cavity, thus completely isolating the inside of the needle sheath 120 from the outside world. During the removal of the sampling device, as the bone marrow tissue sample slides within the needle sheath 120, it creates a negative pressure within the sealed sampling cavity. This negative pressure firmly adheres to the bone marrow tissue within the needle sheath 120, preventing the sample from falling out, shifting, or being disturbed by external factors during removal, ensuring the integrity of the bone marrow tissue sample, and further improving the reliability of the sampling.

[0032] In one embodiment, the bone marrow biopsy sampling device for precise positioning provided by the present invention further includes a limiting component for controlling the drilling depth of the needle sheath 120.

[0033] Specifically, the limiting assembly includes an adjusting rod 150, a sliding sleeve 160, and a locking unit.

[0034] The upper end of the needle core 130 is provided with an outward-facing limiting groove 133. The adjusting rod 150 can coaxially pass through the needle core 130 and be embedded in the limiting groove 133. The lower wall surface of the rotating block 140 is completely in contact with the upper wall surface of the adjusting rod 150, further maintaining the axial position of the adjusting rod 150 and the needle core 130. Connecting rods extend downward from both ends of the adjusting rod 150. The sliding sleeve 160 is connected to the connecting rod of the adjusting rod 150, and the sliding sleeve 160 is slidably connected to the outer wall of the connecting cylinder at the lower end of the handle 110, and can move axially along the outer wall of the connecting cylinder.

[0035] The locking unit includes a locking cylinder 170 and a one-way structure. The one-way structure includes multiple elastic plates 171 and multiple inclined blocks 162. The locking cylinder 170 is an annular cylindrical structure, coaxially sleeved on the outside of the sliding sleeve 160. The elastic plates 171 are elastic sheet-like structures, and multiple elastic plates 171 are uniformly fixed along the axial direction on the inner wall of the locking cylinder 170, with all elastic plates 171 extending obliquely upward toward the axis of the locking cylinder 170. Multiple inclined blocks 162 are uniformly fixed along the axial direction on the outer wall of the sliding sleeve 160, with the outer wall surface of each inclined block 162 inclined downward toward the axis of the sliding sleeve 160. The inclination angle of the inclined block 162 matches the inclination angle of the elastic plates 171.

[0036] When the needle core 130 drives the drill bit 131 to perform drilling, the adjusting rod 150, sliding sleeve 160, and locking cylinder 170 all move synchronously with the needle core 130. After drilling is completed, the needle core 130 drives the adjusting rod 150, sliding sleeve 160, and locking cylinder 170 to move upward synchronously by rotating the rotating block 140. When the first external thread 132 on the needle core 130 is completely disengaged from the fixing block 111, the upper end of the sliding sleeve 160 forms a preset distance with the lower wall of the handle 110, which is the preset sampling length. Subsequently, the locking cylinder 170 is moved closer to the skin. During this process, the elastic plate 171 on the inner wall of the locking cylinder 170 undergoes elastic deformation under the action of the inclined surface of the inclined block 162, moving closer to the inner wall of the locking cylinder 170, and then passing over multiple inclined blocks 162, so that the locking cylinder 170 can move axially along the sliding sleeve 160 until the lower end face of the locking cylinder 170 is completely in contact with the skin surface. At this point, the elastic plate 171 returns to its original position due to elastic recovery, and its upper end tightly abuts against the lower wall of the inclined block 162, preventing the locking cylinder 170 from moving away from the skin. This ensures that the needle core 130, rotating block 140, adjusting rod 150, sliding sleeve 160, and locking cylinder 170 remain absolutely stationary relative to the skin, with only the handle 110 and needle sheath 120 capable of axial drilling. After the locking cylinder 170 is in contact with the skin, the handle 110 drives the needle sheath 120 to drill downwards axially to collect bone marrow tissue. When the lower wall of the handle 110 is completely abutting against the upper wall of the sliding sleeve 160, the handle 110 and needle sheath 120 cannot continue to move downwards because the sliding sleeve 160 is stationary relative to the skin, thus completing the sampling operation. This process eliminates the need to completely remove and reinsert the needle core 130, thus avoiding the positive pressure created by air compression between the needle core 130 and the needle sheath 120 when the needle core 130 is reinserted into the needle sheath 120, which could cause the bone marrow tissue sample to be impacted by the airflow and detached from the sampling area.

[0037] Furthermore, an adjustment structure is provided between the adjustment rod 150 and the sliding sleeve 160. The adjustment structure is used to adjust the position of the sliding sleeve 160 on the adjustment rod 150, thereby changing the sampling length of the needle sleeve 120.

[0038] The adjustment structure includes a slot 151 and a locking block 161. The slot 151 is disposed on the wall surface of the connecting rod of the adjusting rod 150 facing the sliding sleeve 160. Multiple locking blocks 161 are disposed evenly along the axial direction on the outer wall of the sliding sleeve 160 facing the connecting rod. Each locking block 161 can be precisely embedded in the slot 151 to fix the relative position of the sliding sleeve 160 and the adjusting rod 150.

[0039] When the sampling length needs to be adjusted, during the assembly of the sampling device, the current locking block 161 is disengaged from the slot 151 and the locking blocks 161 in other positions are inserted into the slot 151. This changes the axial relative position of the sliding sleeve 160 and the adjusting rod 150, thereby changing the preset distance between the upper end of the sliding sleeve 160 and the lower wall of the handle 110. Ultimately, the sampling length of the needle sleeve 120 is adjustable, and the tight fit between the locking block 161 and the slot 151 ensures the stability of the sampling length.

[0040] Furthermore, the locking cylinder 170 has a detachable, petal-like structure, comprising two adjacent petals. Each petal can open and close radially along the sliding sleeve 160, allowing the elastic plate 171 to completely detach from the inclined block 162. A reset elastic element is fixedly disposed between the lower ends of the two adjacent petals. The reset elastic element is configured as an elastic connecting rope 172, with its two ends fixedly connected to the two petals respectively. The elastic force of the elastic connecting rope 172 always acts on the two adjacent petals, ensuring that the two petals are tightly fitted together when no external force is applied, thus maintaining the overall structural stability of the locking cylinder 170.

[0041] When it is necessary to remove the valve of the locking cylinder 170, adjust the sampling length, or reset the component, a radial compressive force is applied to the lower ends of the two valves. This compressive force overcomes the elastic force of the elastic connecting rope 172, driving the upper ends of the valves to separate. The elastic plate 171 moves synchronously with the valves away from the axis of the sliding sleeve 160, eventually completely disengaging from the tilting block 162. At this point, the sliding sleeve 160 can completely disengage from the valve of the locking cylinder 170. After disengaging the valve of the locking cylinder 170 from the sliding sleeve 160, the sliding sleeve 160 is disengaged from the connecting rod of the adjusting rod 150, and the axial position of the sliding sleeve 160 on the adjusting rod 150 is adjusted. Then, by compressing the lower end of the valve of the locking cylinder 170, the valve of the locking cylinder 170 is moved to the initial position near the handle 110 on the outer side of the sliding sleeve 160. When the squeezing force on the lower end of the valve is removed, the elastic force of the elastic connecting rope 172 will instantly drive the two separated valves to stick together and reset, restoring the overall structure of the locking cylinder 170, so that the elastic piece 171 returns to the working position matching the tilting block 162, ensuring the unidirectional relative movement and tight engagement of the elastic piece 171 and the tilting block 162 during subsequent use.

[0042] Specifically, after the sampling operation is completed, squeeze the lower ends of the two valves of the locking cylinder 170 to separate the two valves of the locking cylinder 170 radially and completely disengage them from the sliding sleeve 160. Then, disengage the locking block 161 on the sliding sleeve 160 from the locking groove 151 of the adjusting rod 150. Twist the rotating block 140 to separate it from the needle core 130, and then pull the adjusting rod 150 out from the upper end of the needle core 130. At this point, the needle core 130 can be removed from the upper end of the needle sleeve 120, completing the replacement and disposal of the needle core 130. Next, loosen the threaded connection between the needle sleeve 120 and the lower end connecting cylinder of the handle 110, completely disassembling the needle sleeve 120 from the connecting cylinder and discarding it.

[0043] When replacing a new part, first screw the new needle sleeve 120 onto the connecting sleeve at the lower end of the handle 110. Insert the new needle core 130 into the needle sleeve 120, tightening the first external thread 132 of the needle core 130 with the first internal thread of the fixing block 111, ensuring that the multiple cutting flaps of the drill bit 131 fully extend out of the lower end port of the needle sleeve 120 and are separated from each other. Slide the adjusting rod 150 onto the upper end of the needle core 130, and screw the rotating block 140 to fix it to the needle core 130. Precisely engage the pre-set locking block 161 on the sliding sleeve 160 into the locking groove 151 of the adjusting rod 150. Press the lower ends of the two flaps of the locking cylinder 170, causing the two flaps of the locking cylinder 170 to engage with the sliding sleeve 160. The elasticity of the elastic connecting rope 172 ensures that the flaps fit together, completing the part replacement.

[0044] The needle sheath 120 and needle core 130 are components that directly contact bone marrow tissue and must be replaced after use. The handle 110, rotating block 140, fixing block 111, adjusting rod 150, sliding sleeve 160, and locking cylinder 170 are structures that do not directly contact the sample and possess sufficient structural strength and disinfection resistance, allowing for multiple reuses after proper disinfection. This approach satisfies the hygiene requirements for single-use of sample contact components in medical procedures, avoiding the risk of cross-infection, while also reducing overall operating costs through the reuse of other components, thus balancing safety and economy.

[0045] In some embodiments, the bone marrow biopsy sampling device for precise positioning provided by the present invention includes the following operating steps during use: S100, preset sampling parameters and initial position settings.

[0046] S110, preset sampling length. Based on the patient's bone marrow sampling requirements, the position of the sliding sleeve 160 on the adjusting rod 150 is set to lock the drilling depth of the needle sleeve 120, i.e., the sampling length.

[0047] S120, Assemble the tool. Insert the needle core 130 into the needle sleeve 120, so that the first external thread 132 of the needle core 130 engages with the first internal thread of the fixing block 111; the drill bit 131 is in the unfolded state. Then, install the adjusting rod 150 and the sliding sleeve 160, and insert the locking block 161 on the sliding sleeve 160 into the corresponding locking groove 151 of the adjusting rod 150 to fix the relative position. Then, fit the locking cylinder 170 onto the outside of the sliding sleeve 160.

[0048] S130, Align the distal end of the needle sheath 120 of the instrument with the patient's puncture site, and prepare to drill.

[0049] S200, using drill bit 131 to drill holes in the bone cortex.

[0050] S210, the operator holds the handle 110 and rotates the handle 110 to drive the needle core 130 and drill bit 131 to rotate. The drill bit 131 cuts the bone cortex in the unfolded state to form a hole with the same diameter as the outer diameter of the needle sleeve 120, eliminating the resistance to subsequent drilling of the needle sleeve 120.

[0051] S220, continue rotating the handle 110 until the drill bit 131 completely penetrates the bone cortex, reaching the predetermined drilling depth. At this time, the drill bit 131 remains in the extended state, and the hole diameter matches the needle sleeve 120.

[0052] S300, switch drill bit 131 from the extended state to the closed state.

[0053] S310, rotate the rotating block 140 to make the needle core 130 move upward along the axis, driving the drill bit 131 to retract into the needle sleeve 120.

[0054] S320, during the movement of the needle core 130, the cutting edge of the drill bit 131 slides relative to the tapered inclined surface at the far end of the needle sleeve 120, and gradually closes under the guidance of the inclined surface until the adjacent cutting edges are completely in contact.

[0055] S330, when the needle core 130 moves to the second position, the first external thread 132 of the needle core 130 is completely disengaged from the first internal thread of the fixing block 111, and the needle sleeve 120 can move freely relative to the needle core 130. At this time, the drill bit 131 is in the closed state and is in sealed contact with the inner wall of the needle sleeve 120.

[0056] The S400 needle sheath 120 was used to drill into the bone marrow and collect samples.

[0057] S410, the locking cylinder 170 is moved axially along the sliding sleeve 160 toward the skin. The elastic piece 171 on the inner wall of the locking cylinder 170 passes over the inclined block 162 on the sliding sleeve 160 until the lower end of the locking cylinder 170 is tightly fitted to the skin. The elastic piece 171 engages with the inclined block 162 to prevent the locking cylinder 170 from moving in the opposite direction, thereby fixing the relative position of the sliding sleeve 160 and the skin.

[0058] S420, rotate handle 110 to move needle sheath 120 downward relative to needle core 130, drilling into bone marrow tissue. The distal end of needle sheath 120 wraps around bone marrow tissue, and the sample enters the hollow cavity of needle sheath 120.

[0059] S430, when the lower end of the handle 110 abuts against the upper end of the sliding sleeve 160, the needle sleeve 120 stops moving and the drilling depth reaches the preset sampling length to ensure accurate sampling.

[0060] S500, remove the instrument and process the sample.

[0061] S510, the entire sampling device is pulled out. Because the drill bit 131 is in the closed state and sealed with the inner wall of the needle sheath 120, negative pressure is generated when the sample slides inside the needle sheath 120, adsorbing bone marrow tissue and preventing the sample from falling out.

[0062] S520, rotate the rotating block 140 to move the needle core 130 downward, pushing the sample out from the distal end of the needle sheath 120 to obtain a complete bone marrow tissue sample for subsequent testing.

[0063] S600, disinfect reusable parts and replace disposable parts.

[0064] S610, squeeze the flap of the locking cylinder 170 to disengage the elastic piece 171 from the tilting block 162, and remove the locking cylinder 170. Disconnect the sliding sleeve 160 from the adjusting rod 150, loosen the rotating block 140 and remove the needle core 130, then disassemble the needle sheath 120. The needle sheath 120 and needle core 130 are disposable parts and must be discarded.

[0065] S620, install the new needle sleeve 120 onto the handle 110, insert the new needle core 130 and engage the first external thread 132 with the retaining block 111. Reassemble the adjusting rod 150, sliding sleeve 160 and locking cylinder 170, ensuring that the retaining block 161 is engaged in the retaining groove 151 and the locking cylinder 170 is reset. The instrument is now ready for the next sampling.

[0066] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0067] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of the invention. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements all fall within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the appended claims.

Claims

1. A precise bone marrow biopsy sampling device, characterized in that, The application relates to a bone marrow drilling device. The device comprises a needle sleeve for drilling into bone marrow and sampling; a needle core movably arranged inside the needle sleeve, the distal end of the needle core being provided with a deformable drill bit, the drill bit having an unfolded state for drilling and a folded state for sealing contact with the inner wall of the needle sleeve, and the outer diameter of the drill bit being equal to the outer diameter of the needle sleeve when the drill bit is in the unfolded state; the needle sleeve being movable relative to the needle core to drill into bone marrow when the drill bit is in the folded state; and a driving assembly capable of driving the needle core to retract the drill bit into the needle sleeve so that the drill bit is switched from the unfolded state to the folded state. The driving assembly comprises a fixed block and a rotating block, the fixed block being fixedly connected to the needle sleeve and connected to the needle core through a threaded segment, the rotating block being fixedly connected to the needle core and capable of driving the needle core to move along the axial direction relative to the fixed block by rotating the rotating block, and the threaded segment being disengaged from the fixed block when the drill bit is in the folded state. The device further comprises a limiting assembly for controlling the drilling depth of the needle sleeve.

2. The precisely positioned bone marrow biopsy sampling instrument of claim 1, wherein, The limiting assembly comprises an adjusting rod, a sliding sleeve and a locking unit, the adjusting rod being connected to the needle core and capable of moving synchronously with the needle core along the axial direction of the needle sleeve, the sliding sleeve being connected to the adjusting rod, and the locking unit being capable of fixing the relative position of the sliding sleeve and the skin to limit the drilling depth of the needle sleeve through the sliding sleeve when the needle sleeve drills into bone marrow.

3. The precisely positioned bone marrow biopsy sampling instrument of claim 1, wherein, An adjusting structure is arranged between the adjusting rod and the sliding sleeve, the adjusting structure being used for adjusting the position of the sliding sleeve on the adjusting rod to adjust the drilling depth of the needle sleeve.

4. The precisely positioned bone marrow biopsy sampling instrument of claim 3, wherein, The adjusting structure comprises a clamping groove arranged on the adjusting rod and a plurality of clamping blocks, the clamping blocks being fixedly arranged on the sliding sleeve, and each clamping block being capable of being embedded into the clamping groove to fix the relative position of the sliding sleeve and the adjusting rod.

5. The precisely positioned bone marrow biopsy sampling instrument of claim 4, wherein, The locking unit comprises a locking cylinder and a one-way structure, the locking cylinder being sleeved outside the sliding sleeve and capable of sliding relative to the sliding sleeve, and the one-way structure allowing the locking cylinder to move on the sliding sleeve towards the skin and limiting reverse movement thereof.

6. The precisely positioned bone marrow biopsy sampling instrument of claim 5, wherein, The one-way structure comprises a plurality of elastic sheets arranged on the inner wall of the locking cylinder and a plurality of inclined blocks arranged on the outer wall of the sliding sleeve, the inclined blocks being capable of passing over the elastic sheets when the locking cylinder moves on the sliding sleeve towards the skin.

7. The precisely positioned bone marrow biopsy sampling instrument of claim 4, wherein, The elastic sheets and the inclined blocks are engaged when the locking cylinder has a reverse movement trend on the sliding sleeve.

8. The precisely positioned bone marrow biopsy sampling instrument of claim 7, wherein, The locking cylinder comprises at least two adjacent petals, the petals being capable of moving along the radial direction of the sliding sleeve so that the elastic sheets can be disengaged from the inclined blocks. A reset elastic member is arranged between the adjacent petals, the elastic force of the reset elastic member being used for making the adjacent petals adhere to each other.

9. The precisely positioned bone marrow biopsy sampling instrument of claim 8, wherein, ​ 10. The precisely positioned bone marrow biopsy sampling instrument of claim 9, wherein, ​

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