Band-aid type product suitable for repairing microbial corrosion surface and preparation method thereof
By designing a biomimetic adhesive layer, an antibacterial repair core layer, and a protective peeling layer for adhesive bandage-like products, the problem of microbial corrosion inside manned spacecraft cabins has been solved, achieving efficient antibacterial, rapid repair, and safe maintenance in microgravity environments.
Patent Information
- Application Number
- CN202511561407.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-29
- Publication Date
- 2026-03-06
AI Technical Summary
Microbial corrosion inside manned spacecraft cabins leads to material structure failure. Existing antibacterial coatings are difficult to apply in microgravity environments, their adhesion is affected by temperature and humidity differences, and self-healing materials have excessively long curing times, which cannot meet the needs of rapid maintenance.
Develop a bandage-like product comprising a biomimetic adhesive layer, an antibacterial repair core layer, and a protective peel-off layer. PDMS micropillar arrays are fabricated using laser micromachining, combined with silver nanoclusters and mesoporous silica nanoparticles. Ultraviolet curing technology is employed for rapid repair, and an antistatic polyester film is added to ensure safety.
It achieves efficient antibacterial and rapid repair in microgravity environments, with an adhesion strength of up to 1.2 N/cm2, a curing time of ≤10 seconds, and an antibacterial rate of >99.9%, meeting the safety standards for spacecraft cabins and suitable for rapid maintenance in microgravity environments.
Smart Images
Figure CN121608491A_ABST
Abstract
Description
Technical Field
[0001] This invention belongs to the field of spacecraft cabin maintenance technology, specifically relating to a band-aid-like product suitable for repairing microbially corroded surfaces and its preparation method. Background Technology
[0002] The temperature and humidity environment inside the sealed cabin of a manned spacecraft is suitable for human habitation, but it also provides excellent conditions for the growth of microorganisms. Microorganisms are ubiquitous in their living environment. In the confined space environment of a manned spacecraft, they are affected by the special space environment and undergo mutations. These microorganisms (such as Bacillus and Aspergillus) form biofilms on the metal or composite material surfaces inside the manned spacecraft cabin. Their metabolic products (such as organic acids and extracellular polysaccharides) cause pitting and peeling of materials, threatening the safety and sealing of equipment, thus affecting the safety of the environment inside the manned spacecraft cabin and the health of astronauts.
[0003] The existing antibacterial coating technology has the following main shortcomings:
[0004] 1) Traditional spray-applied antibacterial coatings require complex equipment, are difficult to apply under microgravity, and are prone to releasing volatile organic compounds;
[0005] 2) The adhesion of conventional repair tapes currently available on the market is significantly affected by temperature and humidity differences, and they lack long-lasting antibacterial properties;
[0006] 3) Existing self-healing materials have a curing time that is too long (>30 min), which cannot meet the needs of rapid maintenance inside the cabin. Summary of the Invention
[0007] The purpose of this invention is to overcome the aforementioned defects and provide a bandage-like product and its preparation method suitable for repairing microbially corroded surfaces, solving the technical problem that microbial corrosion on the inner surface of manned spacecraft cabins in orbit easily leads to material structural failure. This invention is suitable for microgravity environments and combines highly efficient antibacterial properties, rapid repair capabilities, and astronaut health and safety protection functions.
[0008] To achieve the above-mentioned objectives, the present invention provides the following technical solution:
[0009] A bandage-like product suitable for repairing microbially corroded surfaces includes a biomimetic adhesion layer, an antibacterial repair core layer, and a protective peeling layer arranged sequentially.
[0010] The protective peel layer is used to protect the biomimetic adhesion layer and the antibacterial repair core layer when they are not peeled off;
[0011] The antibacterial repair core layer includes epoxy acrylate, mesoporous silica nanoparticles, and silver nanoclusters. The silver nanoclusters are loaded in the pores of the mesoporous silica nanoparticles, and the mesoporous silica nanoparticles loaded with silver nanoclusters are dispersed in the epoxy acrylate. Quaternary ammonium salt antibacterial groups are grafted onto the surface of the mesoporous silica nanoparticles.
[0012] The biomimetic adhesion layer is used to adhere to the surface to be repaired after the protective peeling layer is peeled off, so that the antibacterial repair core layer covers the surface to be repaired. The biomimetic adhesion layer includes a substrate, a microstructure and an adhesive layer arranged in sequence, wherein the microstructure is a PDMS micropillar array.
[0013] Furthermore, the thickness of the adhesive bandage product is 0.3-1.0mm;
[0014] In the biomimetic adhesion layer, the substrate has a thickness of 25–80 μm and a coefficient of thermal expansion ≤3 × 10⁻⁶. -6 A polyimide film with a temperature of / ℃; the adhesive layer thickness is 25~50μm, and the adhesive layer uses medical-grade silicone pressure-sensitive adhesive.
[0015] Furthermore, the PDMS micropillar array was fabricated using laser micromachining. The diameter of the PDMS micropillar array was 10–30 μm, the height of the pillars was 20–40 μm, and the PDMS micropillar array had a hexagonal close-packed structure with a hexagonal close-packed spacing of 8–12 μm.
[0016] Furthermore, in the antibacterial repair core layer, the pore size of the mesoporous silica nanoparticles is 8–12 nm;
[0017] In the antibacterial repair core layer, the Ag nanoclusters have a particle size of 1–3 nm. 50 The loading of silver nanoclusters in mesoporous silica nanoparticles is 10–20 wt%.
[0018] Furthermore, the epoxy acrylate resin is a light-cured epoxy acrylate resin with a curing time of ≤10 seconds.
[0019] Furthermore, the protective release layer has a surface resistivity of ≤1×10⁻⁶. 6 Ω-sized antistatic polyester film.
[0020] The above-mentioned method for preparing a bandage-like product suitable for repairing microbially corroded surfaces includes:
[0021] S1 ablates a microporous array on the surface of a PDMS film, and after removing carbonization residue by plasma cleaning, a PDMS micropillar array is obtained.
[0022] S2 applies the adhesive used for the adhesive layer to the back of the PDMS micropillar array, and forms the adhesive layer after curing; a polyimide film is used as a substrate to be laminated with the adhesive layer.
[0023] S3 disperses mesoporous silica nanoparticles in an ethanol solution of 3-aminopropyltriethoxysilane, introduces amino groups on the surface of the mesoporous silica nanoparticles by reflux, and then reacts the amino-containing mesoporous silica nanoparticles with dodecyl dimethyl benzyl ammonium chloride to graft quaternary ammonium salt antibacterial groups onto the surface of the mesoporous silica nanoparticles.
[0024] S4 mixes AgNO3 with sodium citrate and undergoes a reduction reaction to obtain silver nanoclusters; the silver nanoclusters are then loaded into the pores of mesoporous silica nanoparticles using a vacuum impregnation method.
[0025] S5 disperses mesoporous silica nanoparticles loaded with silver nanoclusters in polyurethane acrylate prepolymer or epoxy acrylate prepolymer, casts them into a film, and then covers a PET substrate.
[0026] S6 involves hot-pressing the biomimetic adhesive layer obtained through steps S1 and S2, the antibacterial repair core layer obtained through steps S3, S4 and S5, and the protective peeling layer together, then die-cutting and vacuum-sealing to obtain the adhesive bandage product.
[0027] Furthermore, in step S1, an ultraviolet nanosecond laser is used to ablate the micro-hole array on the surface of the PDMS thin film. The wavelength of the ultraviolet nanosecond laser is 355nm and the power is 0.8-1.5W.
[0028] Furthermore, in step S3, the mass ratio of mesoporous silica nanoparticles to 3-aminopropyltriethoxysilane is 1:0.5-2; the reflux temperature range is 70-85℃, and the reflux time is 4h-8h.
[0029] When amino-containing mesoporous silica nanoparticles react with dodecyl dimethyl benzyl ammonium chloride, the molar ratio of amino to dodecyl dimethyl benzyl ammonium chloride is 1:1.5-6, the reaction temperature is 25-60℃, and the reaction time is 18h-36h.
[0030] Furthermore, in step S4, the molar ratio of AgNO3 to sodium citrate is 3-8:1;
[0031] In step S6, the conditions for hot-pressing composite are: temperature 70-80℃, pressure 0.2-0.3MPa, and time 10 seconds.
[0032] Compared with the prior art, the present invention has at least one of the following advantages:
[0033] (1) The present invention achieves an adhesion strength of 1.2 N / cm by laser micromachining of PDMS micropillar arrays. 2 This enabled microgravity-adaptive adhesion.
[0034] (2) The adhesive bandage product of the present invention is photocured by ultraviolet LED (365nm), which can form a dense protective layer within 10 seconds and can quickly respond to repair.
[0035] (3) This invention achieves synergistic antibacterial effect of quaternary ammonium salt-nano silver with an inhibition rate of >99.9%, which is beneficial for achieving long-term targeted antibacterial effect;
[0036] (4) All materials of the adhesive bandage product of this invention have passed the NASASTD-6001 test, with no risk of particulate matter falling off, and meet the safety design standards for cabins. Attached Figure Description
[0037] Figure 1 This is a schematic diagram of the product structure of the present invention. Detailed Implementation
[0038] The features and advantages of the present invention will become clearer and more apparent from the following detailed description.
[0039] The term “exemplary” as used herein means “serving as an example, embodiment, or illustration.” Any embodiment illustrated herein as “exemplary” is not necessarily to be construed as superior to or better than other embodiments. Although various aspects of embodiments are shown in the accompanying drawings, the drawings are not necessarily drawn to scale unless specifically indicated otherwise.
[0040] This invention develops a bandage-like product suitable for microbial corrosion of surfaces inside manned spacecraft cabins. The product structure consists of a three-layer flexible patch (total thickness 0.3-1.0 mm), as shown below. Figure 1 It includes a biomimetic adhesion layer 1, an antibacterial repair core layer 2, and a protective peeling layer 3.
[0041] (1) Bionic Adhesion Layer 1: The bionic adhesion layer consists of three parts, namely the base layer 11, the microstructure and the adhesive layer 12.
[0042] Substrate: Polyimide film (25-80 μm thick);
[0043] Microstructure: PDMS micropillar arrays (pillar diameter 10-30μm, height 20-40μm, hexagonal close-packed spacing 8-12μm) were fabricated using laser micromachining technology;
[0044] Adhesive layer: Medical grade silicone pressure-sensitive adhesive (Dow Corning 7-9800, TML < 0.1%), thickness 25-50μm.
[0045] (2) Antibacterial repair core layer: mainly includes mesoporous silica nanoparticles 21 loaded with silver nanoclusters, which are dispersed in epoxy acrylate resin.
[0046] Carrier: Mesoporous silica nanoparticles (pore size 8-12 nm), with quaternary ammonium salt antibacterial groups grafted onto the surface;
[0047] Antibacterial agent: Sustained-release nano-silver clusters (Ag) 50 (Particle size 1-3 nm), loading 10-20 wt%;
[0048] Repair substrate: UV-cured epoxy acrylate resin (curing time ≤ 10 seconds).
[0049] (3) Protective peel layer:
[0050] The protective release layer 3 mainly consists of an antistatic polyester film 31 (surface resistance ≤ 1×10⁻⁶). 6 Composed of Ω), pre-cut into easy-tear strips.
[0051] The above-mentioned adhesive bandage-like product, suitable for microbial corrosion of surfaces inside manned spacecraft cabins, is prepared using the following method:
[0052] 1) Preparation of biomimetic adhesion layer
[0053] a. Molding of PDMS micropillar arrays:
[0054] A micropore array (pore size 15-25 μm, depth 20-35 μm) was ablated on the surface of a PDMS thin film using an ultraviolet nanosecond laser (wavelength 355 nm, power 0.8-1.5 W); then, plasma cleaning (O2, 50 W, 5 min) was used to remove carbonization residues to obtain a hexagonal close-packed micropillar structure.
[0055] b. Pressure-sensitive adhesive lamination:
[0056] The silicone pressure-sensitive adhesive is coated onto the back of the PDMS micropillar layer using a roller coating process. Immediately afterward, polyimide is pressed onto the uncured pressure-sensitive adhesive and cured at 60°C for 20 minutes.
[0057] 2) Preparation of the antibacterial repair core layer
[0058] a. Mesoporous silica modification:
[0059] Mesoporous silica was dispersed in an ethanol solution of 3-aminopropyltriethoxysilane (APTES) (3%-8% v / v), with a mass ratio of mesoporous silica to APTES of 1:(0.5-2). The mixture was refluxed at 70-85°C for 4-8 hours to introduce amino groups. Then, it was reacted with dodecyl dimethyl benzyl ammonium chloride (DDAC, 0.05-0.2M) at 25-60°C for 18-36 hours to graft quaternary ammonium salt groups.
[0060] b. Silver nanocluster loading:
[0061] AgNO3 (0.05M) was mixed with sodium citrate (1% w / v) and the mixture was reduced at 70℃~85℃ for 1 hour to obtain Ag. 50 Nanoclusters; Ag was impregnated using a vacuum impregnation method. 50 Loaded into mesoporous silica channels (loading efficiency > 90%).
[0062] c. Photocurable matrix composite:
[0063] Load Ag 50 Mesoporous silica (8-12 wt%) is dispersed in polyurethane acrylate prepolymer or epoxy acrylate prepolymer (containing 2 wt% photoinitiator TPO); cast into a film (100-200 μm thick) and cover an anti-stick PET substrate.
[0064] 3) Product Integration
[0065] The biomimetic adhesion layer, antibacterial repair core layer and protective peel layer are hot-pressed together (temperature 70-80℃, pressure 0.2-0.3MPa, time 10 seconds); then die-cut into (5-10cm)×(1-3cm) standard patches and vacuum sealed.
[0066] Example:
[0067] Example 1: Repair products suitable for use under normal temperature and humidity conditions
[0068] In this embodiment, the adhesive bandage product is prepared according to the following method:
[0069] 1) Preparation of biomimetic adhesion layer
[0070] a. Molding of PDMS micropillar arrays:
[0071] A micropore array (pore size 20 μm, depth 30 μm) was ablated on the surface of a PDMS thin film using an ultraviolet nanosecond laser (wavelength 355 nm, power 1.2 W); then, plasma cleaning (O2, 50 W, 5 min) was used to remove carbonization residues to obtain a hexagonal close-packed micropillar structure.
[0072] b. Pressure-sensitive adhesive lamination:
[0073] The silicone pressure-sensitive adhesive is coated onto the back of the PDMS micropillar layer using a roller coating process. Immediately afterward, polyimide is pressed onto the uncured pressure-sensitive adhesive and cured at 60°C for 20 minutes.
[0074] 2) Preparation of the antibacterial repair core layer
[0075] a. Mesoporous silica modification:
[0076] Mesoporous silica (1 g) was dispersed in an ethanol solution of 3-aminopropyltriethoxysilane (APTES) (5% v / v) and refluxed for 6 hours to introduce amino groups. Then it was reacted with dodecyl dimethyl benzyl ammonium chloride (DDAC, 0.1 M) for 24 hours to graft quaternary ammonium salt groups.
[0077] b. Silver nanocluster loading:
[0078] AgNO3 (0.05M) was mixed with sodium citrate (1% w / v) and the mixture was reduced at 80°C for 1 hour to obtain Ag. 50 Nanoclusters; Ag was impregnated using a vacuum impregnation method. 50 Loaded into mesoporous silica channels (loading efficiency > 90%).
[0079] c. Photocurable matrix composite:
[0080] Load Ag 50 Mesoporous silica (10 wt%) was dispersed in epoxy acrylate prepolymer (containing 2 wt% photoinitiator TPO); cast into a film (150 μm thick) and covered with an anti-stick PET substrate.
[0081] 3) Product Integration
[0082] The biomimetic adhesion layer, antibacterial repair core layer, and protective release layer are hot-pressed together (temperature 80℃, pressure 0.3MPa, time 10 seconds); then die-cut into 10cm×3cm standard patches and vacuum-sealed.
[0083] The resulting adhesive bandage product's formation state and key parameters:
[0084] The product's macroscopic structure consists of a three-layer flexible patch with a total thickness of 0.68±0.05mm. The structure is as follows: protective release layer → antibacterial repair core layer (approximately 100μm thick after curing) → biomimetic adhesion layer (polyimide substrate / pressure-sensitive adhesive / PDMS micropillar array).
[0085] Biomimetic adhesion layer parameters: The PDMS micropillar array is hexagonally close-packed, with a pillar diameter of 20±2μm, a pillar height of 30±2μm, and a spacing of 10±1μm.
[0086] Antibacterial repair core layer parameters: mesoporous silica carrier with a pore size of 10±2nm, silver nanoclusters (Ag) 50 The particle size is 2.0±0.5nm, and the actual loading in the carrier is 13.8wt%.
[0087] Performance Tests and Results:
[0088] The product obtained in this embodiment was subjected to the following tests:
[0089] 1. Adhesion performance test: Following ASTM D3330 standard, a 90° peel test was performed on the simulated cabin aluminum alloy surface, and the adhesion strength was measured to be 1.18 ± 0.15 N / cm. 2 This indicates that it meets the high adhesion requirements under microgravity conditions.
[0090] 2. Curing performance test: using a 365nm ultraviolet LED lamp (power 100mW / cm²). 2 When the product surface is irradiated, the liquid core layer completely solidifies into a dry, hard, and dense protective layer within 8 seconds.
[0091] 3. Antibacterial performance test: In accordance with GB / T 31402 standard, Staphylococcus aureus and Escherichia coli were subjected to a 24-hour contact test, and the inhibition rate was >99.9%, which proved the high efficiency of the quaternary ammonium salt-nano silver synergistic antibacterial system.
[0092] 4. Safety compliance testing: Volatile organic compound emissions and particulate matter shedding tests were conducted according to NASAST D-6001, and the results all met the highest safety standards, confirming the safety of the product for use inside spacecraft cabins.
[0093] Test results show that the adhesive bandage product prepared in this embodiment fully meets the expected goals of the present invention, and has core functions such as rapid response, efficient adhesion, long-lasting antibacterial effect and cabin safety. It is suitable for rapid on-orbit repair of the interior surface of manned spacecraft cabins.
[0094] Example 2: Enhanced product suitable for high humidity environments
[0095] This embodiment aims to provide a bandage product that can maintain excellent initial tack and antibacterial properties even in higher humidity environments.
[0096] 1) Preparation of biomimetic adhesion layer
[0097] a. Molding of PDMS micropillar arrays:
[0098] A micropore array (pore size 25 μm, depth 35 μm) was ablated on the surface of a PDMS thin film using an ultraviolet nanosecond laser (wavelength 355 nm, power 1.5 W); then, plasma cleaning (O2, 50 W, 5 min) was used to remove carbonization residues to obtain a hexagonal close-packed micropillar structure.
[0099] b. Pressure-sensitive adhesive lamination:
[0100] The silicone pressure-sensitive adhesive with added hydrophobic fumed silica (0.5 wt%) was coated onto the back of the PDMS micropillar layer using a roller coating process. Immediately afterward, a polyimide film was pressed onto the uncured pressure-sensitive adhesive and cured at 60°C for 20 minutes to form a complete biomimetic adhesion layer.
[0101] 2) Preparation of the antibacterial repair core layer
[0102] a. Mesoporous silica modification:
[0103] Mesoporous silica (1 g) was dispersed in an ethanol solution of 3-chloropropyltriethoxysilane (APTES) (5% v / v) and refluxed for 6 hours to introduce amino groups. Then it was reacted with tetradecyl dimethyl benzyl ammonium chloride (0.1 M) for 24 hours to graft longer alkyl chain quaternary ammonium salt groups to enhance hydrophobic interactions with microbial cell membranes.
[0104] b. Silver nanocluster loading:
[0105] AgNO3 (0.05M) was mixed with sodium citrate (1% w / v) and the mixture was reduced at 80°C for 1 hour to obtain Ag. 50 Nanoclusters; Ag was impregnated using a vacuum impregnation method. 50 Loaded into the modified mesoporous silica channels (loading efficiency > 90%).
[0106] c. Photocurable matrix composite:
[0107] Load Ag 50 Mesoporous silica (12 wt% of total mass) was dispersed in polyurethane acrylate prepolymer (containing 2 wt% photoinitiator TPO); a film was formed by casting (wet film thickness 200 μm) and covered with an anti-stick PET substrate to obtain the antibacterial repair core layer precursor. (Note: Polyurethane acrylate has better flexibility and hydrolysis resistance than epoxy acrylate).
[0108] 3) Product Integration
[0109] The biomimetic adhesion layer, antibacterial repair core layer, and protective release layer are hot-pressed together (temperature 80℃, pressure 0.3MPa, time 10 seconds); then die-cut into 10cm×3cm standard patches and vacuum-sealed.
[0110] The resulting adhesive bandage product's formation state and key parameters:
[0111] Product macro structure: It is a three-layer flexible patch with a total thickness of 0.82±0.05mm.
[0112] Biomimetic adhesion layer parameters: PDMS micropillar array with a diameter of 25±2μm, a height of 35±2μm, and a spacing of 12±1μm.
[0113] Antibacterial repair core layer parameters: The actual loading of silver nanoclusters in the carrier is 16.5 wt%.
[0114] Performance Tests and Results:
[0115] Targeted tests were conducted on the product obtained in this embodiment:
[0116] 1. Adhesion test in a high humidity environment: The adhesion strength was tested on the surface of the composite material in a simulated chamber at a relative humidity of 90%, and the measured adhesion strength was 1.05 ± 0.12 N / cm. Compared with the data of Example 1 under normal humidity conditions, the retention rate exceeded 85%, demonstrating excellent high humidity stability.
[0117] 2. Curing performance test: Irradiated with a 365nm ultraviolet LED lamp, the curing time was 9 seconds. Due to the slightly thicker film layer, the curing time increased slightly, but it was still below the design target of 10 seconds.
[0118] 3. Long-lasting antibacterial test: When tested against Pseudomonas aeruginosa (a bacterium commonly found in humid environments), the antibacterial rate was >99.9% after 24 hours and remained >99% after 72 hours, demonstrating the long-lasting antibacterial ability of its longer alkyl chain quaternary ammonium salt in humid environments.
[0119] 4. Flexibility test: The product was tested for conical bending according to ASTM D522 standard. No cracking or delamination was observed, which shows that the polyurethane acrylate matrix provides better flexibility.
[0120] Test results demonstrate that this embodiment successfully prepared an enhanced repair product particularly suitable for high-humidity areas inside the cabin (such as sanitary areas and condensation risk areas) by increasing the micropillar size to enhance mechanical interlocking ability, adding a hydrophobic agent to the pressure-sensitive adhesive, using a quaternary ammonium salt with a longer alkyl chain, and selecting a more flexible photocurable resin. This product maintains reliable adhesion and long-lasting antibacterial efficacy even under extreme humidity conditions, further expanding the application scenarios of this invention.
[0121] Example 3: Ultra-flexible thin products suitable for irregularly shaped surfaces
[0122] This embodiment aims to provide a band-aid-like product suitable for irregularly shaped surfaces such as pipes and cable bundles inside spacecraft cabins. Its features are ultra-thinness, ultra-flexibility, and the ability to adapt to curved surfaces for adhesion.
[0123] 1) Preparation of biomimetic adhesion layer
[0124] a. Molding of PDMS micropillar arrays:
[0125] A micropore array (pore size 15 μm, depth 20 μm) was ablated on the surface of a thinner (100 μm) PDMS film using an ultraviolet nanosecond laser (wavelength 355 nm, power 0.8 W); then, plasma cleaning (O2, 50 W, 5 min) was used to remove carbonization residues to obtain a hexagonal close-packed micropillar structure.
[0126] b. Pressure-sensitive adhesive lamination:
[0127] Low-modulus silicone pressure-sensitive adhesive is coated on the back of the PDMS micropillar layer with a thinner thickness (25μm) using a micro-gravure roller coating process. Immediately afterward, an ultra-thin polyimide film (25μm thick) is pressed onto the uncured pressure-sensitive adhesive and cured at 60°C for 20 minutes to form a complete biomimetic adhesion layer.
[0128] 2) Preparation of the antibacterial repair core layer
[0129] a. Mesoporous silica modification:
[0130] Same as Example 1.
[0131] b. Silver nanocluster loading:
[0132] Same as Example 1.
[0133] c. Photocurable matrix composite:
[0134] Load Ag 50 Mesoporous silica (8 wt% of total mass) is dispersed in epoxy acrylate prepolymer (containing 2 wt% photoinitiator TPO); a film is formed by precision casting process (wet film thickness 100 μm) and covered with an anti-stick PET substrate to obtain an antibacterial repair core layer precursor.
[0135] 3) Product Integration
[0136] The biomimetic adhesion layer, antibacterial repair core layer and protective release layer are composited by low-temperature hot pressing (temperature 70℃, pressure 0.2MPa, time 10 seconds); then die-cut into narrow strips of 1cm×5cm and vacuum sealed.
[0137] The resulting adhesive bandage product's formation state and key parameters:
[0138] Product macro structure: It is a three-layer ultra-flexible patch with a total thickness of 0.35±0.03mm.
[0139] Biomimetic adhesion layer parameters: PDMS micropillar array with a diameter of 15±1.5μm, a height of 20±1.5μm, and a spacing of 8±1μm.
[0140] Antibacterial repair core layer parameters: The actual loading of silver nanoclusters in the carrier is 12.1 wt%. The thickness of the cured film is approximately 70 μm.
[0141] Performance Tests and Results:
[0142] Targeted tests were conducted on the product obtained in this embodiment:
[0143] 1. Curved Surface Adhesion Test: The product was adhered to the outer wall of a 5mm diameter aluminum alloy rod, and its circumferential peel strength was measured, reaching 0.85±0.10N / cm. This demonstrates excellent adaptability to small pipe-like curved surfaces.
[0144] 2. Flexibility test: The flexibility test was conducted in accordance with ASTM D3167. The product can be bypassed by a 3mm diameter mandrel without damage, which far exceeds the flexibility requirements of ordinary circuit boards.
[0145] 3. Low-temperature flexibility test: The product remains flexible and brittle at -20℃, with an adhesion strength retention rate of >80%.
[0146] 4. Curing performance test: Irradiated with a 365nm ultraviolet LED lamp, the curing time is 6 seconds. Due to the thinner film layer, the ultraviolet light has better penetration and the curing speed is faster.
[0147] 5. Confined Space Construction Simulation Test: In the confined space of the simulation chamber, this narrow and elongated product demonstrated excellent operability and adhesion to complex surfaces.
[0148] Test results demonstrate that this embodiment successfully developed an ultra-thin, ultra-flexible adhesive bandage product by comprehensively reducing the thickness of each layer, selecting low-modulus adhesives and flexible resins, and optimizing processing parameters. This product is particularly suitable for adhering to various irregularly shaped surfaces inside spacecraft cabins, such as cables, small-diameter pipe joints, and complex corners, solving the problem of ineffective adhesion of traditional rigid repair materials and expanding the application scope of this invention.
[0149] The present invention has been described in detail above with reference to specific embodiments and exemplary examples; however, these descriptions should not be construed as limiting the present invention. Those skilled in the art will understand that various equivalent substitutions, modifications, or improvements can be made to the technical solutions and embodiments of the present invention without departing from the spirit and scope of the invention, and all such modifications and improvements fall within the scope of the present invention. The scope of protection of the present invention is defined by the appended claims.
[0150] The contents not described in detail in this specification are common knowledge to those skilled in the art.
Claims
1. A band-aid product suitable for microbial corrosion surface repair, characterized in that, The adhesive layer, the antibacterial repair core layer and the protective peeling layer are sequentially arranged. The protective peeling layer is used to protect the adhesive layer and the antibacterial repair core layer when not peeled. The antibacterial repair core layer comprises epoxy acrylate, mesoporous silica nanoparticles and nano silver clusters, the nano silver clusters are loaded in the pore channels of the mesoporous silica nanoparticles, the mesoporous silica nanoparticles loaded with the nano silver clusters are dispersed in the epoxy acrylate, and the surface of the mesoporous silica nanoparticles is grafted with quaternary ammonium salt antibacterial groups. The adhesive layer is used to adhere to the surface to be repaired after the protective peeling layer is peeled, so that the antibacterial repair core layer covers the surface to be repaired, and the adhesive layer comprises a substrate, a microstructure and an adhesive layer which are sequentially arranged, wherein the microstructure is a PDMS microcolumn array.
2. A band-aid product for repairing a microbially corroded surface according to claim 1, wherein The thickness of the adhesive plaster product is 0.3-1.0mm. In the biomimetic adhesive layer, the substrate is a polyimide film with a thickness of 25-80 μm and a thermal expansion coefficient of ≤3×10 -6 / ℃; the adhesive layer has a thickness of 25-50 μm and is made of a medical-grade silicone pressure-sensitive adhesive.
3. A band-aid product for repairing a microbially corroded surface according to claim 1, wherein The PDMS microcolumn array is prepared by laser micromachining, the column diameter of the PDMS microcolumn array is 10-30μm, the column height is 20-40μm, the PDMS microcolumn array is a hexagonal close-packed structure, and the hexagonal close-packed spacing is 8-12μm.
4. The Band-Aid® product for repairing microbiologically influenced corrosion surfaces according to claim 1, characterized in that In the antibacterial repair core layer, the pore diameter of the mesoporous silica nanoparticles is 8-12nm. In the antibacterial repair core layer, the particle size of the nano-silver cluster is 1-3 nm Ag 50 , and the loading amount of the nano-silver cluster in the mesoporous silica nanoparticles is 10-20 wt%.
5. A band-aid product for repairing a microbially corroded surface according to claim 1, wherein The epoxy acrylate resin is a photocuring epoxy acrylate resin with a curing time of less than 10 seconds.
6. A band-aid product for repairing a microbially corroded surface according to claim 1, wherein The protective release layer uses an antistatic polyester film with a surface resistance of < 1 x 10 6 Ω.
7. A method for the preparation of a band-aid product suitable for the repair of microbiologically corroded surfaces according to any one of claims 1 to 6, characterized in that, It comprises the following steps: S1: ablation of a micro-hole array on the surface of a PDMS film, and removal of carbonized residues after plasma cleaning to obtain a PDMS microcolumn array; S2: coating of an adhesive layer with glue on the back of the PDMS microcolumn array, and formation of the adhesive layer after curing; A polyimide film is used as the substrate and is combined with the adhesive layer; S3: dispersion of mesoporous silica nanoparticles in an ethanol solution of 3-aminopropyl triethoxysilane, introduction of amino groups on the surface of the mesoporous silica nanoparticles by reflux, and reaction of the mesoporous silica nanoparticles with amino groups with dodecyl dimethyl benzyl ammonium chloride to graft quaternary ammonium salt antibacterial groups on the surface of the mesoporous silica nanoparticles; S4: mixing of AgNO3 and sodium citrate, reduction reaction to obtain nano silver clusters, and loading of the nano silver clusters into the pore channels of the mesoporous silica nanoparticles by vacuum impregnation; S5: dispersion of the mesoporous silica nanoparticles loaded with the nano silver clusters in a polyurethane acrylate prepolymer or an epoxy acrylate prepolymer, and casting into a film on a PET substrate; S6: hot pressing of the adhesive layer obtained by steps S1 and S2, the antibacterial repair core layer obtained by steps S3, S4 and S5, and the protective peeling layer, vacuum packaging after die cutting, and obtaining of an adhesive plaster product.
8. A method of preparing a band-aid product suitable for microbial corrosion surface repair according to claim 7, characterized in that, In step S1, a UV nanosecond laser is used to ablate a micro-hole array on the surface of a PDMS film, the wavelength of the UV nanosecond laser is 355nm, and the power is 0.8-1.5W.
9. A method for preparing a bandage-like product suitable for repairing microbially corroded surfaces according to claim 7, characterized in that, In step S3, the mass ratio of the mesoporous silica nanoparticles to 3-aminopropyl triethoxysilane is 1:0.5-2, the reflux temperature is 70-85℃, and the reflux time is 4h-8h. The molar ratio of the amino group of the mesoporous silica nanoparticles to the dodecyl dimethyl benzyl ammonium chloride is 1:1.5-6, the reaction temperature is 25-60 DEG C, and the reaction time is 18h-36h.
10. A method for preparing a bandage-like product suitable for repairing microbially corroded surfaces according to claim 7, characterized in that, In step S4, the molar ratio of AgNO3 to sodium citrate is 3-8:1; In step S6, the hot-pressing conditions are as follows: temperature 70-80 DEG C, pressure 0.2-0.3 MPa, and time 10 seconds.