Manufacturing method of disposable gastrointestinal tract nutrition device

Abstract

The invention relates to the technical field of manufacturing of medical instruments, and discloses a manufacturing method of a disposable gastrointestinal tract nutrition device, which comprises the following steps: preparing raw materials of a nutrition infusion tube A, a liquid storage bag B, a connector assembly C and a flow control assembly D according to a formula proportion, and detecting the raw materials according to the standard of the medical instruments, so that unqualified raw materials are avoided from the source; raw materials are subjected to drying pretreatment and an accurate forming process to ensure that the flexibility of a medical tube section at the tail end of a nutrition infusion tube A is matched, stimulation of an intubation tube to gastrointestinal mucosa is reduced, and then through thermocompression welding, adhesive bonding and sealing and multi-dimensional function detection, it is ensured that all connecting parts of the nutrition device are free of liquid leakage and stable and controllable in infusion speed; the problems of cross infection risk and poor treatment effect caused by liquid leakage or infusion fluctuation are solved, finally, an ideal state after sterilization can be effectively achieved by applying an ethylene oxide sterilization technology, safety guarantee is provided for medical supplies, and the health of a patient is practically maintained.

Description

Technical Field

[0001] This invention relates to the field of medical device manufacturing technology, specifically a method for manufacturing a disposable gastrointestinal nutrition device. Background Technology

[0002] In the field of medical care, enteral nutrition support is a crucial means of maintaining vital signs for postoperative and critically ill patients. However, traditional reusable enteral nutrition devices, due to the need for frequent sterilization and the risk of cross-infection, are increasingly unable to meet the safety and convenience requirements of modern medicine. Furthermore, existing technologies generally suffer from the following drawbacks: First, the nutrition infusion tubing is often made of rigid materials, which can easily scratch the gastrointestinal mucosa during insertion, leading to patient discomfort or even bleeding; second, the sealing at the connection between the reservoir bag and the tubing is insufficient, easily causing leakage during transportation or use, resulting in nutrient waste and environmental pollution; third, the flow rate adjustment precision is low, and the drip rate fluctuates greatly, making it difficult to meet the clinical need for stable infusion. Although some improvement schemes attempt to alleviate these problems by changing the tubing material or optimizing the structure, limitations in material properties, manufacturing processes, and cost control still prevent a balance between biocompatibility, mechanical strength, and safety. For example, simply increasing the flexibility of the tubing material may lead to tubing collapse, affecting infusion efficiency, while excessive pursuit of sealing sacrifices ease of operation. Therefore, there is an urgent need for a disposable gastrointestinal nutrition device that combines high safety, a good user experience, and stable function to completely solve the comprehensive defects of existing technologies. Summary of the Invention

[0003] (a) Technical problems to be solved

[0004] To address the shortcomings of existing technologies, this invention provides a method for manufacturing a disposable gastrointestinal nutrition device, which has the advantages of excellent biocompatibility, strong sealing, and no chemical residues. It solves the problems of high risk of cross-infection, large intubation trauma, high sterilization residues, and poor infusion stability of traditional nutrition devices.

[0005] (II) Technical Solution

[0006] To achieve the above objectives, the present invention provides the following technical solution: a method for manufacturing a disposable gastrointestinal nutrition device, comprising the following steps:

[0007] Step 1: Raw material preparation: Prepare the raw materials for nutrient infusion tubing A, reservoir bag B, connecting connector assembly C and flow control assembly D according to the formula ratio, and test the raw materials according to medical device standards.

[0008] Step 2, Molding of Components A, B, C and D: Under different set conditions, the raw materials of nutrient infusion tube A, reservoir bag B, connecting connector assembly C and flow control component D are dried and pretreated, and then nutrient infusion tube A, reservoir bag B, connecting connector assembly C and flow control component D are prepared by extrusion and injection molding equipment respectively. Finally, the appearance of the molded components is inspected.

[0009] Step 3: Pre-assembly of nutrient infusion tube A and flow control component D: Connect one end of the drip chamber of flow control component D to one end of nutrient infusion tube A by hot-press welding to form a pre-assembled infusion tube-flow control component;

[0010] Step 4: Connection of the pre-assembled body and the connecting connector assembly C: The other end of the nutrient infusion tube in the pre-assembled body obtained in Step 3 is bonded to one end of the connecting connector assembly C with medical-grade adhesive, and an airtightness test is performed at the same time.

[0011] Step 5: Connection of the pre-assembled body to the storage bag B: Connect the other end of the flow control component in the infusion tube-flow control component-connector assembly obtained in Step 4 to the outlet of the storage bag B through a threaded connection. After connection, tighten and pass the pressure test to form the complete nutrient set body.

[0012] Step Six: Functional Performance Testing: Perform multiple functional tests on the complete nutrient supply unit, including flow regulation testing, anti-backflow testing, and pressure resistance testing.

[0013] Step 7, Aseptic Processing: Place the nutrient unit body that has passed the functional test into an aseptic sterilization cabinet for packaging, and then sterilize it using an ethylene oxide sterilization process.

[0014] Preferably, the raw materials and their proportions of the nutrient infusion tube A are: 65%–75% medical-grade polyvinyl chloride; 15%–25% medical-grade plasticizer; 8%–12% medical-grade silicone; and 2%–5% medical-grade color masterbatch.

[0015] Preferably, the nutrient infusion tube A is manufactured using an extrusion molding process. Pretreated medical-grade polyvinyl chloride, medical plasticizer, medical-grade silicone, and medical-grade color masterbatch are mixed in a certain proportion and fed into the extruder barrel. The mixture is melted and plasticized at a barrel temperature of 175-180℃ and a screw speed of 45-50 r / min. The mixture is then drawn into a tubular shape through a special mold of an extrusion and injection molding equipment. After being cooled and shaped in a cooling water tank at a water temperature of 25-30℃, the tube is marked with scale lines by a laser marking machine with a power of 8-10W and a marking speed of 150-200 mm / s. Finally, the tube is cut to a preset length for later use.

[0016] Preferably, the raw materials and their proportions of the liquid storage bag B are: 90% to 95% medical-grade polyethylene; 8% to 10% medical-grade polyvinyl chloride.

[0017] Preferably, the liquid storage bag B is manufactured using a blow molding process. Medical-grade polyvinyl chloride granules are fed into the hopper of a blow molding machine and melted at a barrel temperature of 155-160°C and a die temperature of 180-185°C. The blow molding process forms a bag of a preset capacity, and capacity markings are printed on the surface of the bag. Then, medical-grade polyvinyl chloride granules are fed into an injection molding machine and injection molded at a barrel temperature of 190-195°C and a die temperature of 45-50°C to form a threaded bottle cap for later use.

[0018] Preferably, the raw materials and their proportions of the connecting joint assembly C are: 75% to 85% medical-grade acrylonitrile-butadiene-styrene copolymer resin; 10% to 15% medical-grade silicone sealing ring; and 5% to 10% medical-grade polycarbonate.

[0019] Preferably, the connecting body of the connector assembly C is manufactured using an injection molding process. Medical-grade acrylonitrile-butadiene-styrene copolymer resin is fed into an injection molding machine and injection molded into a main structure with an interface under conditions of barrel temperature 205-210℃ and mold temperature 65-70℃. Then, medical-grade polycarbonate material is placed into a compression molding machine and molded into a preset valve shape under conditions of temperature 190-200℃ and pressure 8-12MPa. Finally, the silicone sealing ring and anti-reflux valve are assembled to the connector body to form a complete connecting connector for later use.

[0020] Preferably, the raw materials and their proportions of the flow control component D are: 85%–90% medical-grade polyvinyl chloride; 10%–15% medical-grade silicone.

[0021] Preferably, the main body of the drip chamber in the flow control component D is manufactured by injection molding. Medical-grade polyvinyl chloride granules are fed into an injection molding machine and injection molded into a transparent drip chamber under conditions of barrel temperature of 195-200℃ and mold temperature of 55-60℃. Then, polypropylene granules are made into a regulator shell, and silicone rollers are assembled into the shell to form an adjustable flow component for later use.

[0022] Preferably, in step three, the pre-assembly welding temperature of the nutrient infusion tube A and the flow control component D is controlled at 135-140℃, the duration is controlled between 12 and 14 seconds, and the welding pressure is 0.8-1 MPa.

[0023] Compared with the prior art, the present invention provides a method for manufacturing a disposable gastrointestinal nutrition device, which has the following beneficial effects:

[0024] 1. This invention improves the convenience of clinical operation and the comfort of patients by using an integrated process of drying-blending-extrusion-laser marking for the nutrition infusion tube, combined with the design of a medical silicone section at the end of the tube, and the assembly process of ABS injection molding-PC molding-silicone sealing ring for the connecting connector assembly. This allows medical staff to insert the tube more smoothly and reduce the need for repeated intubation, while also reducing the stimulation of the nutrition device on the patient's gastrointestinal mucosa and improving the patient's tolerance during nutrition infusion.

[0025] 2. This invention achieves the beneficial effect of enhancing the overall performance stability and durability of the product through the integrated PVC blow molding-injection molding-threading process of the storage bag, the precise extrusion molding process of the nutrient infusion tube, and the hot-press welding process of the nutrient infusion tube and the flow control component. It can ensure that the nutrition set is not easily damaged by drops during transportation, there is no leakage during use, the scale lines are clear and not easily worn, and it can meet the clinical nutrition infusion needs for a long time.

[0026] 3. This invention improves product safety and infusion accuracy by using sterilization methods combined with flow control components, avoiding potential harm to patients from residual substances, and precisely adjusting the infusion rate to ensure stable infusion of nutritional preparations according to clinical needs, thereby reducing patient discomfort caused by fluctuations in the infusion rate. Attached Figure Description

[0027] Figure 1 This is a flowchart of the method of the present invention. Detailed Implementation

[0028] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0029] Please see Figure 1 A method for manufacturing a disposable gastrointestinal feeding device includes the following steps:

[0030] Step 1: Raw material preparation: Prepare the raw materials for nutrient infusion tubing A, reservoir bag B, connecting connector assembly C and flow control assembly D according to the formula ratio. At the same time, test the biocompatibility and purity (such as heavy metal content and amount of harmful substances leached) of the raw materials according to medical device standards to ensure that the raw materials are qualified and ready for use.

[0031] Step 2, Molding of Components A, B, C and D: Under different set conditions, the raw materials of nutrient infusion tube A, reservoir bag B, connecting connector assembly C and flow control component D are dried and pretreated (to remove moisture and avoid air bubbles after molding). Then, nutrient infusion tube A, reservoir bag B, connecting connector assembly C and flow control component D are prepared by extrusion and injection molding equipment respectively. Finally, the molded parts are subjected to appearance inspection to remove cracks, deformation and burrs, so as to reject unqualified products.

[0032] Step 3: Pre-assembly of nutrient infusion tubing A and flow control assembly D: Connect one end of the drip chamber of flow control assembly D to one end of nutrient infusion tubing A using a hot-press welding process (ensure the weld is strong and leak-free) to form a pre-assembled infusion tubing-flow control assembly for later use.

[0033] Step 4: Connection between the pre-assembled assembly and the connecting connector assembly C: In the pre-assembled assembly obtained in Step 3, the other end of the nutrient infusion tube is bonded to one end of the connecting connector assembly C using medical-grade adhesive (the adhesive must meet biocompatibility requirements and be odorless and non-toxic after bonding). At the same time, an airtightness test is performed (0.2-0.3MPa compressed air is introduced, and the assembly is immersed in water to observe for no bubbles) to ensure a sealed connection.

[0034] Step 5: Connection of the pre-assembled body to the storage bag B: Connect the other end of the flow control component in the infusion tube-flow control component-connector assembly obtained in Step 4 to the outlet of the storage bag B via a thread (the outlet of the storage bag is threaded and matches the drip chamber interface). After connection, tighten and pass the pressure test (inject 0.1-0.2MPa liquid into the storage bag, let it stand for 5-8 minutes and observe for no leakage) to form the complete nutrient set body;

[0035] Step Six: Functional Performance Testing: Multiple functional tests are performed on the complete nutrient feeder body, including flow regulation testing, anti-backflow testing, and pressure resistance testing. These tests are used to eliminate products that fail the functional tests. Specifically, these tests include:

[0036] (1) Flow rate regulation test: Adjust the flow rate regulator so that the drip rate range meets 20-60 drops / minute (common clinical range);

[0037] (2) Anti-backflow test: Inject simulated nutrient solution into the nutrient container, invert it and observe that there is no liquid backflow;

[0038] (3) Pressure resistance test: Pressurize the storage bag to 0.3-0.5MPa and maintain for 10-15 seconds without rupture;

[0039] Step 7, Aseptic Processing: Place the nutrient unit body that has passed the functional test into an aseptic sterilization cabinet for packaging, and then sterilize it using an ethylene oxide sterilization process for later use.

[0040] The advantages are: through step one (raw material biocompatibility and purity testing), step two (precise molding and appearance screening of each component), steps three through six (multi-stage sealing and full functional performance testing), and step seven (ethylene oxide sterilization process with no chemical residue), the problems of high risk of cross-infection, large intubation trauma, high sterilization residue, and poor infusion stability of traditional nutrition devices are solved. Specifically, the strict testing of raw material biocompatibility and purity in step one prevents the release of harmful substances from unqualified raw materials, thus avoiding health risks to patients. Step two, through drying pretreatment and precise molding processes, ensures the safety of nutrient delivery. The medical silicone segment at the end of the infusion tube (A) is flexible and has a uniform inner and outer diameter, reducing irritation to the gastrointestinal mucosa during insertion and addressing the issue of significant trauma associated with traditional feeding devices. Steps three through six involve hot-press welding, adhesive sealing, and multi-dimensional functional testing (flow rate, anti-backflow, pressure resistance) to ensure leak-free connection points and stable, controllable infusion rates. This effectively reduces the risk of cross-infection and poor treatment outcomes caused by fluid leakage or infusion fluctuations. Step seven utilizes ethylene oxide sterilization technology to safeguard patient health and comprehensively enhance the safety and infusion stability of the feeding device.

[0041] Specifically, the raw materials and their proportions for nutrition infusion tubing A are as follows: 65%–75% medical-grade polyvinyl chloride; 15%–25% medical-grade plasticizer; 8%–12% medical-grade silicone (used for the soft section at the end of the tubing to reduce gastrointestinal irritation); and 2%–5% medical-grade color masterbatch (used to prepare graduation lines for easy observation of infusion progress).

[0042] Specifically, the nutrient infusion tube A is manufactured using an extrusion molding process. Pretreated medical-grade polyvinyl chloride, medical-grade plasticizer, medical-grade silicone, and medical-grade color masterbatch are mixed in a specific ratio and fed into the extruder barrel. The mixture is melted and plasticized at a barrel temperature of 175-180℃ and a screw speed of 45-50 r / min. The mixture is then drawn into a tubular shape through a special mold in the extrusion and injection molding equipment. After cooling and shaping in a cooling water bath at a temperature of 25-30℃, the tube is marked with graduation lines using a laser marking machine with a power of 8-10W and a marking speed of 150-200 mm / s. Finally, it is cut to a preset length for later use.

[0043] Through the integrated process of drying, blending, extrusion, and laser marking, the inner and outer diameters of the tube are made uniform (Φ4.0mm±0.1mm), the graduations are clear and wear-resistant, and the silicone section at the end has a Shore A of 35-40. This greatly reduces the irritation to the gastrointestinal mucosa, thereby achieving a more comfortable clinical cannulation and visualized infusion.

[0044] Specifically, the raw materials and their proportions for the liquid storage bag B are: 90%–95% medical-grade polyethylene (PVC, used for liquid storage bags, lightweight and acid and alkali resistant); 8%–10% medical-grade polyvinyl chloride (used for liquid storage bottle caps, with good sealing performance).

[0045] Specifically, the storage bag B is manufactured using a blow molding process. Medical-grade polyvinyl chloride granules are fed into the hopper of a blow molding machine and melted at a barrel temperature of 155-160℃ and a die temperature of 180-185℃. The blow molding process produces a bag of a preset capacity, and capacity markings are printed on the surface of the bag. Then, medical-grade polyvinyl chloride granules are fed into an injection molding machine and injection molded at a barrel temperature of 190-195℃ and a die temperature of 45-50℃ to produce a threaded bottle cap for later use.

[0046] Through the above-mentioned PVC blow molding-injection molding-threading integrated process, the bag wall thickness is 0.15mm±0.02mm, it can withstand a drop of 1.2m without breaking, and the cap torque is 0.8-1.0 N·m to seal, thus achieving the effect of being lightweight, acid and alkali resistant, and leak-proof during transportation.

[0047] Specifically, the raw materials and their proportions for connector component C are as follows: medical-grade acrylonitrile-butadiene-styrene copolymer resin (ABS, used for the connector body, high strength and easy to process) 75%–85%; medical-grade silicone sealing ring (used for sealing to prevent leakage) 10%–15%; medical-grade polycarbonate (PC, used for anti-reflux valves, with good elasticity and corrosion resistance) 5%–10%.

[0048] Specifically, the connecting body of connector component C is manufactured using injection molding. Medical-grade acrylonitrile-butadiene-styrene copolymer resin is fed into an injection molding machine and injection molded into a main structure with an interface under conditions of barrel temperature 205-210℃ and mold temperature 65-70℃. Then, medical-grade polycarbonate material is placed into a compression molding machine and molded into a preset valve shape under conditions of temperature 190-200℃ and pressure 8-12MPa. Finally, the silicone sealing ring and anti-reflux valve are assembled onto the connector body to form a complete connecting connector for later use.

[0049] Through the above-mentioned process of ABS injection molding-PC molding-silicone sealing ring assembly, the tensile strength of the joint is ≥30MPa, the valve opening pressure difference is ≤0.5kPa, and the permanent deformation of the silicone ring is ≤10%, thereby achieving the effects of quick insertion and removal, anti-backflow, and long-term sealing without leakage.

[0050] Specifically, the raw materials and their proportions for the flow control component D are: 85%–90% medical-grade polyvinyl chloride (PVC, used for the main body of the dripping bucket, which is transparent and easy to observe the dripping speed); and 10%–15% medical-grade silicone (used for the flow rate regulator roller, which has good friction and flexibility).

[0051] Specifically, the main body of the dripping bucket in the flow control component D is made by injection molding. Medical-grade polyvinyl chloride granules are put into the injection molding machine and injection molded into a transparent dripping bucket under the conditions of barrel temperature of 195-200℃ and mold temperature of 55-60℃. Then, polypropylene granules are made into a regulator shell, and silicone rollers are assembled into the shell to form an adjustable flow component for later use.

[0052] Through the above-mentioned injection molding-silicone roller pressing process, the light transmittance of the dripping chamber is ≥90%, the static friction coefficient of the roller is 0.35-0.45, and the linear error of flow rate adjustment is ≤±5%, thereby achieving the effect of intuitive and visible dripping speed and precise and stable adjustment.

[0053] Specifically, in step three, the pre-assembly welding temperature of the nutrient infusion tube A and the flow control component D is controlled at 135-140℃, the duration is controlled between 12 and 14 seconds, and the welding pressure is 0.8-1MPa to ensure that the weld is firm and leak-free. Through hot-press welding, the weld tensile strength is ≥15N, the burst pressure is ≥0.6MPa, and the connection is firm and leak-free.

[0054] The disposable nutrition device of the present invention and a conventional nutrition device were applied to a real-world scenario, and the comparative data are listed in Table 1 below:

[0055] Table 1

[0056]

[0057] The conclusion drawn from Table 1 is that the feeder manufactured using the method of this invention is superior to the traditional PVC feeder in terms of insertion success rate, sealing performance, scale clarity, flow accuracy, and safety.

[0058] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A method of manufacturing a gastroenteral feeding set for single use, c h a r a c t e r i s e d in that The method comprises the following steps: Step one, raw material preparation: prepare the raw materials of the nutrient infusion tube A, the storage bag B, the connecting joint assembly C and the flow control assembly D according to the formula proportion, and detect the raw materials according to the medical instrument standard; Step two, A, B, C and D component forming: dry pretreat the raw materials of the nutrient infusion tube A, the storage bag B, the connecting joint assembly C and the flow control assembly D under different setting conditions, then prepare the nutrient infusion tube A, the storage bag B, the connecting joint assembly C and the flow control assembly D through extrusion and injection molding equipment respectively, and finally detect the appearance of the formed components; Step three, pre-assembly of the nutrient infusion tube A and the flow control assembly D: connect one end of the flow control assembly D and one end of the nutrient infusion tube A through hot pressure welding process to form a pre-assembly of the infusion tube and the flow control assembly; Step four, connection of the pre-assembly and the connecting joint assembly C: bond the other end of the nutrient infusion tube in the pre-assembly obtained in step three and one end of the connecting joint assembly C through medical-grade adhesive, and simultaneously conduct air tightness detection; Step five, connection of the pre-assembly and the storage bag B: connect the other end of the flow control assembly in the pre-assembly obtained in step four and the outlet of the storage bag B through screw connection, tighten after connection and conduct pressure test to form a complete nutrient device main body; Step six, functional performance detection: conduct multiple functional detections of the complete nutrient device main body, including flow regulation detection, anti-reflux detection and pressure resistance detection; Step seven, sterile treatment: place the nutrient device main body that passes the functional detection into a sterile sterilization cabinet for packaging, and then conduct sterilization by adopting ethylene oxide sterilization process.

2. The method of manufacturing a gastroenteral feeding set for single use according to claim 1, characterized in that: The raw material of the nutrient infusion tube A and its proportion are as follows: 65-75% of medical-grade polyvinyl chloride, 15-25% of medical plasticizer, 8-12% of medical silica gel and 2-5% of medical-grade color master batch.

3. The method of manufacturing a gastroenteral feeding set for single use according to claim 2, characterized in that: The nutrient infusion tube A is prepared by adopting extrusion molding process, i.e. mixing the pretreated medical-grade polyvinyl chloride, medical plasticizer, medical silica gel and medical-grade color master batch according to the proportion, feeding them into the extruder barrel, melting and plasticizing under the condition of barrel temperature 175-180℃ and screw rotation speed 45-50r / min, then dragging them through the special mold of the extrusion and injection molding equipment to form a tubular shape, cooling and setting in the cooling water tank with water temperature 25-30℃, printing scale lines by the laser marking machine with power 8-10W and marking speed 150-200mm / s, and finally cutting into the preset length for standby.

4. The method of manufacturing a gastroenteral feeding set for single use according to claim 1, wherein: The raw material of the storage bag B and its proportion are as follows: 90-95% of medical-grade polyethylene and 8-10% of medical-grade polyvinyl chloride.

5. The method of manufacturing a gastroenteral feeding set for single use according to claim 4, characterized in that: The storage bag B is prepared by adopting blow molding process, i.e. feeding the medical-grade polyvinyl chloride particles into the hopper of the blow molding machine, melting under the condition of barrel temperature 155-160℃ and mold temperature 180-185℃, and then forming a bag body with a preset capacity by the blow molding machine, and printing capacity scale on the surface of the bag body; then feeding the medical-grade polyvinyl chloride particles into the injection molding machine, injection molding under the condition of barrel temperature 190-195℃ and mold temperature 45-50℃ to form a threaded bottle cap for standby.

6. The method of manufacturing a gastroenteral feeding set for single use according to claim 1, wherein: The raw material and its proportion of the connecting joint assembly C are: medical grade acrylonitrile-butadiene-styrene copolymer resin 75%-85%; medical grade silica seal ring 10%-15%; medical grade polycarbonate 5%-10%.

7. The method of manufacturing a gastroenteral feeding set according to claim 6, wherein: The connecting body of the connecting joint assembly C adopts injection molding process, the medical grade acrylonitrile-butadiene-styrene copolymer resin is put into an injection molding machine, and the main body structure with an interface is injection molded under the conditions of a barrel temperature of 205-210 DEG C and a mold temperature of 65-70 DEG C; then the medical grade polycarbonate material is put into a mold pressing forming machine, and a preset valve shape is molded under the conditions of a temperature of 190-200 DEG C and a pressure of 8-12 MPa; finally, the silica seal ring and the anti-reflux valve are assembled to the joint body to form a complete connecting joint, ready for use.

8. The method of manufacturing a gastroenteral feeding set according to claim 1, wherein: The raw material and its proportion of the flow control assembly D are: medical grade polyvinyl chloride 85%-90%; medical grade silica 10%-15%.

9. The method of manufacturing a gastroenteral feeding set according to claim 8, wherein: The drip main body in the flow control assembly D adopts injection molding process, the medical grade polyvinyl chloride particles are put into an injection molding machine, and a transparent drip is injection molded under the conditions of a barrel temperature of 195-200 DEG C and a mold temperature of 55-60 DEG C; then the polypropylene particles are made into an adjuster shell, and the silica roller is assembled into the shell to form a flow adjustable assembly, ready for use.

10. The method of manufacturing a gastroenteral feeding set according to claim 1, wherein: In the step three, the pre-assembly welding temperature of the nutrition infusion tube A and the flow control assembly D is controlled at 135-140 DEG C, the time length is controlled between 12-14 s, and the welding pressure is 0.8-1 MPa.

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