Preparation process of effervescent tablets capable of being rapidly disintegrated

Abstract

The invention discloses a preparation technology of effervescent tablets capable of being disintegrated rapidly, an effervescent tablet press is used, the effervescent tablet press comprises a main body unit, a pressing unit, a cleaning unit and a material conveying unit, the main body unit comprises an operation table, a lower mold is fixedly arranged on the operation table, and a plurality of pressing grooves are formed in the lower mold; the pressing unit comprises a top plate, a tablet pressing assembly is arranged on the top plate, and an ejection assembly used for ejecting effervescent tablets is arranged in the lower mold; the cleaning unit comprises a push rod, moving assemblies used for moving are symmetrically arranged on the push rod, a dust removal assembly used for cleaning is arranged in the push rod, and a transmission assembly is arranged between the moving assemblies and the dust removal assembly. When the push rod moves, the pressing rod, the end face of the circular plate and the top face of the lower mold are cleaned, meanwhile, dust collection is conducted on powder, residual materials are greatly reduced, dead materials are prevented from being formed, and the quality of effervescent tablets is guaranteed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of effervescent tablet preparation, and in particular to a preparation process of effervescent tablets with rapid disintegration. BACKGROUND

[0002] As a common solid preparation, effervescent tablets have the advantages of convenient use and rapid effect, and are widely used in the fields of medicine, health care and food. The preparation process usually includes the steps of raw material mixing, granulation, drying, lubrication, tabletting and the like. Among them, the tabletting process is the key link to determine the appearance quality, mechanical strength and disintegration performance of the tablets.

[0003] However, in the existing tabletting process of effervescent tablets, some materials are inevitably left on the inner wall of the die hole after each lifting of the punch. These residues are easily pressed into the side or bottom of the new tablet during the next tabletting. Since they have been compressed under high pressure in the previous tabletting, their reactivity is significantly reduced, becoming so-called "dead material". The mixing of such dead material into the new tablet not only may cause uneven overall strength of the tablet, but also may form difficult-to-dissolve "black spots" during the dissolution process, affecting the appearance and dissolution uniformity of the product. SUMMARY

[0004] This section aims to summarize some aspects of the embodiments of the present application and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the abstract and title of the specification to avoid obscuring the purpose of this section, abstract and title, and such simplifications or omissions cannot be used to limit the scope of the present application.

[0005] To solve the above technical problems, the present application provides the following technical solutions: A preparation process of effervescent tablets with rapid disintegration uses an effervescent tablet press, which includes a main unit, a pressing unit, a cleaning unit and a material conveying unit. The specific process when using the above effervescent tablet press includes: S1, citric acid, tartaric acid and sodium bicarbonate are selected as acid-base reaction components, cross-linked povidone and microcrystalline cellulose are selected as disintegration promoters, and mannitol is selected as a soluble filler. All raw materials are vacuum dried at 40-50 DEG C for 2-4 hours, and the water content is controlled to be less than or equal to 0.5%; S2, all raw materials are sieved through a 100-mesh sieve to obtain powders with uniform particle size; S3, the dried powders are mixed uniformly according to the formula proportion, a small amount of lubricant and flow aid is added at the end of the mixing, and the mixing is continued for 2-3 minutes; S4, the mixture is directly sent to the tablet press for tabletting; S5, immediately after tabletting, the tablets are sealed and packaged with aluminum foil to prevent moisture absorption.

[0006] The main unit comprises an operation table, a lower mold fixedly arranged on the operation table, and a plurality of pressing grooves formed in the lower mold; The pressing unit comprises a top plate fixedly connected to the operation table, a tablet pressing assembly arranged on the top plate, and a material ejection assembly arranged in the lower mold for ejecting effervescent tablets. The cleaning unit comprises a push rod slidably connected to the lower mold in the left-right direction, a moving assembly symmetrically arranged on the push rod, a dust removal assembly arranged in the push rod for cleaning, and a transmission assembly arranged between the moving assembly and the dust removal assembly.

[0007] As a preferred scheme of the preparation process of the rapidly disintegrating effervescent tablets, the tablet pressing assembly comprises a hydraulic telescopic rod fixedly arranged on the top plate, an upper mold fixedly arranged at the bottom end of the hydraulic telescopic rod, and a plurality of pressing rods fixedly connected to the bottom surface of the upper mold.

[0008] As a preferred scheme of the preparation process of the rapidly disintegrating effervescent tablets, the material ejection assembly comprises a plurality of circular plates slidably connected to the inner wall of the pressing groove in the up-down direction, a notch formed in the bottom of the lower mold, a circular rod fixedly connected to the bottom surface of the circular plate and extending into the notch, and a bottom plate fixedly connected to the bottom end of the circular rod, wherein a plurality of electric telescopic rods are symmetrically fixedly connected between the bottom surface of the bottom plate and the operation table.

[0009] As a preferred scheme of the preparation process of the rapidly disintegrating effervescent tablets, the material ejection assembly further comprises a rubber ring fixedly connected to the circular plate, which is in close contact with the inner wall of the pressing groove.

[0010] As a preferred scheme of the preparation process of the rapidly disintegrating effervescent tablets, the moving assembly comprises a motor fixedly installed on a moving plate slidably connected to the side wall of the operation table in the left-right direction, a rotating shaft fixedly connected to the output end of the motor, and a gear wheel fixedly connected to the rotating shaft, wherein a toothed plate is fixedly connected to the side wall of the lower mold, and the gear wheel is in meshing engagement with the toothed plate.

[0011] As a preferred scheme of the preparation process of the rapidly disintegrating effervescent tablets, the dust removal assembly comprises two brush rods, wherein a rectangular slot is formed in the push rod, the two brush rods are symmetrically and rotatably inserted into the push rod and located in the two rectangular slots, a first channel and a second channel are respectively formed in the push rod, the first channel is in communication with the rectangular slot, a dust suction pump is arranged on one side of the push rod, a suction pipe and an exhaust pipe are respectively fixedly connected to the dust suction pump, one end of the suction pipe is fixedly connected to the side wall of the push rod, and the suction pipe is in communication with the second channel.

[0012] As a preferred embodiment of the rapidly disintegrating effervescent tablet preparation process of the present invention, the dust removal assembly further includes an inner rod, the brush rod is hollow, the inner rod is rotatably connected to the inner wall of the brush rod, the brush rod has multiple first openings, the inner rod has a cavity, and the inner rod has a second opening and a third opening respectively.

[0013] As a preferred embodiment of the rapidly disintegrating effervescent tablet preparation process described in this invention, the transmission assembly includes an active transmission wheel, which is fixedly connected to a rotating shaft, and a driven transmission wheel is fixedly connected to the brush rod, wherein the driven transmission wheel meshes with the active transmission wheel.

[0014] As a preferred embodiment of the rapidly disintegrating effervescent tablet preparation process of the present invention, the material conveying unit includes a conveying equipment body, which is disposed on one side of the operating table, and a guide plate is fixedly connected to the lower mold, which extends above the conveying equipment body.

[0015] As a preferred embodiment of the rapidly disintegrating effervescent tablet preparation process described in this invention, the lower mold is symmetrically and elastically slidably connected with side plates, and the outer side wall of the side plates is provided with an inclined surface.

[0016] The beneficial effects of this invention are: 1. After pressing, start the electric telescopic rod to push out the pressed effervescent tablets. Then start the motor to drive the push rod to one side and push the pressed effervescent tablets to the conveyor body. The conveyor body will then transport the pressed effervescent tablets to the next process. The operation is simple and convenient.

[0017] 2. When the push rod moves, it drives the brush rod to rotate, cleaning the pressure rod, the end face of the circular plate, and the top surface of the lower mold. At the same time, the dust pump is started, and the dust is collected from the upper surface of the lower mold, the bottom end of the pressure rod, and the top of the circular plate through the first channel, the second channel, the air extraction pipe, and the air outlet pipe. This greatly reduces the residue of residual material, avoids the formation of "dead material", and ensures the quality of the effervescent tablets. Attached Figure Description

[0018] To more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein: Figure 1 This is a process flow diagram of a rapidly disintegrating effervescent tablet preparation process proposed in this invention; Figure 2 This is a front structural diagram of an effervescent tablet compressor proposed in this invention; Figure 3 for Figure 2 A partial structural diagram; Figure 4 for Figure 3 A partial structural diagram; Figure 5 This is a schematic diagram of a partial cross-sectional structure. Figure 6 for Figure 5 A partial structural diagram; Figure 7 for Figure 6 Enlarged structural diagram at point A in the middle; Figure 8 for Figure 6 A schematic diagram of the cross-sectional structure; Figure 9 for Figure 8 A partial structural diagram; Figure 10 for Figure 8 A schematic diagram of a working state; Figure 11 for Figure 8 A schematic diagram of a working state; Figure 12 for Figure 9 A schematic diagram of a partial cross-sectional structure.

[0019] In the diagram: 100, Main unit; 101, Operating table; 102, Lower mold; 103, Pressing groove; 200, Pressing unit; 201, Top plate; 202, Pressing assembly; 202a, Hydraulic telescopic rod; 202b, Upper mold; 202c, Pressing rod; 203, Ejector assembly; 203a, Circular plate; 203b, Circular rod; 203c, Base plate; 203d, Electric telescopic rod; 203e, Rubber ring; 300, Cleaning unit; 301, Push rod; 302, Moving assembly; 302a, Motor; 302b, Moving plate; 302c, Rotating shaft; 30 2d, Toothed plate; 302e, Moving gear; 303, Dust removal assembly; 303a, Rectangular groove; 303b, Brush rod; 303c, First channel; 303d, Second channel; 303e, Dust pump; 303f, Air extraction pipe; 303g, Air outlet pipe; 303h, Inner rod; 303i, First opening; 303j, Second opening; 303k, Third opening; 304, Transmission assembly; 304a, Driven drive wheel; 304b, Driven drive wheel; 400, Material conveying unit; 401, Conveying equipment body; 402, Guide plate; 403, Side plate. Detailed Implementation

[0020] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0021] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0022] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments.

[0023] Secondly, the present invention is described in detail with reference to the schematic diagrams. When detailing the embodiments of the present invention, for ease of explanation, the cross-sectional views illustrating the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of the present invention. In addition, actual fabrication should include three-dimensional spatial dimensions of length, width, and depth.

[0024] Example 1 Reference Figure 1 This invention provides a process for preparing rapidly disintegrating effervescent tablets: the specific process includes: S1. Citric acid, tartaric acid, and sodium bicarbonate are selected as acid-base reaction components, crospovidone and microcrystalline cellulose are selected as disintegration promoters, and mannitol is selected as a soluble filler. All raw materials are vacuum dried at 40-50℃ for 2-4 hours, and the water content is controlled to ≤0.5% to avoid premature reaction. S2. All raw materials are sieved through a 100-mesh sieve to obtain powder with uniform particle size, which ensures the consistency of subsequent particle forming and disintegration. S3. Mix the dry powder evenly according to the formula ratio. At the end of the mixing process, add a small amount of lubricant (magnesium stearate ≤1%) and flow aid (silica), and continue mixing for 2-3 minutes to avoid coating affecting disintegration. S4. Feed the mixture directly into the tableting machine for tableting; S5. Immediately after tableting, seal the packaging with aluminum foil to prevent moisture absorption.

[0025] Example 2 Reference Figures 2-5 This invention provides a process for preparing rapidly disintegrating effervescent tablets, which uses an effervescent tablet press. The effervescent tablet press includes a main unit 100 and a pressing unit 200, comprising: The main unit 100 includes an operating table 101, on which a lower mold 102 is fixedly installed, and multiple pressing grooves 103 are opened on the lower mold 102. The pressing unit 200 includes a top plate 201, which is fixedly connected to the operating table 101. A tablet pressing assembly 202 is mounted on the top plate 201. The tablet pressing assembly 202 includes a hydraulic telescopic rod 202a, which is fixedly mounted on the top plate 201. An upper mold 202b is fixedly mounted at the bottom end of the hydraulic telescopic rod 202a. Multiple pressure rods 202c are fixedly connected to the bottom surface of the upper mold 202b. The lifting height of the upper mold 202b can be controlled by the hydraulic telescopic rod 202a, facilitating the pressing of effervescent tablets and cleaning of the bottom ends of the pressure rods 202c. A lower mold 102 contains an ejector assembly 203 for ejecting effervescent tablets. The ejector assembly 203 includes multiple circular plates 203a, which are slidably connected to the inner wall of the pressing groove 103 in the vertical direction. 02. A slot is provided at the bottom. A round rod 203b is fixedly connected to the bottom surface of the round plate 203a. The round rod 203b extends into the slot. A base plate 203c is fixedly connected to the bottom end of the round rod 203b. Multiple electric telescopic rods 203d are symmetrically fixed between the bottom surface of the base plate 203c and the operating table 101. The electric telescopic rods 203d can drive the base plate 203c to rise and fall, so that the round plate 203a can rise and fall, pushing out the pressed effervescent tablets for easy collection. The material ejection assembly 203 also includes a rubber ring 203e, which is fixedly connected to the round plate 203a. The rubber ring 203e fits against the inner wall of the pressing groove 103. The setting of the rubber ring 203e allows the round plate 203a to wipe away the powder remaining on the inner wall of the pressing groove 103 while it rises, making it easy to clean.

[0026] In use, the lower mold 102 is fed by an external feeding device, and then the upper mold 202b is pressed by the hydraulic telescopic rod 202a. After pressing, the electric telescopic rod 203d drives the bottom plate 203c to rise, so that the circular plate 203a rises and pushes out the pressed effervescent tablets.

[0027] Example 3 Reference Figures 2-7This invention provides a process for preparing rapidly disintegrating effervescent tablets, which uses an effervescent tablet press. The effervescent tablet press includes a cleaning unit 300 and a feeding unit 400. The cleaning unit 300 includes a push rod 301, which is slidably connected to a lower mold 102 in a left-right direction. Symmetrically arranged on the push rod 301 are moving components 302, which include a motor 302a. A moving plate 302b is slidably connected to the side wall of the operating table 101 in a left-right direction. The motor 302a is fixedly mounted on the moving plate 302b. On plate 302b, a rotating shaft 302c is fixedly connected to the output end of motor 302a. The rotating shaft 302c is rotatably connected to the side wall of push rod 301. A toothed plate 302d is fixedly connected to the side wall of lower mold 102. A moving gear 302e is fixedly connected to the rotating shaft 302c. The toothed plate 302d meshes with the moving gear 302e. By starting motor 302a, the rotating shaft 302c is driven to rotate, causing the moving gear 302e to rotate and move along the toothed plate 302d to one side. The pressed effervescent tablets are pushed to one side by push rod 301. The material conveying unit 400 includes a conveying equipment body 401, which is located on one side of the operating table 101. A guide plate 402 is fixedly connected to the lower mold 102 and extends above the conveying equipment body 401. Effervescent tablets pushed to one side by the push rod 301 can slide down to the conveying equipment body 401 through the guide plate 402. The conveying equipment body 401 transports the pressed effervescent tablets to the next process. Side plates 403 are symmetrically and elastically slidably connected to the lower mold 102. The outer side wall of the side plate 403 has an inclined surface. The side plate 403 blocks the pressed effervescent tablets and prevents them from scattering during the process. At the same time, the device can be fed into the pressing groove 103 by a feeding device located behind the operating table 101, which can press the side plate 403 and move to the top of the lower mold 102.

[0028] When in use, after the effervescent tablets are pressed, the motor 302a is started, which moves to one side along the toothed plate 302d. The pressed effervescent tablets are pushed to one side by the push rod 301. The effervescent tablets pushed to one side by the push rod 301 can slide down to the conveying equipment body 401 through the guide plate 402. The pressed effervescent tablets are then transported to the next process by the conveying equipment body 401.

[0029] Example 4 Reference Figures 7-12 This invention provides a process for preparing rapidly disintegrating effervescent tablets, which uses an effervescent tablet press including a cleaning unit 300, comprising: The cleaning unit 300 includes a push rod 301, which is slidably connected to the lower mold 102 in the left-right direction. The push rod 301 contains a dust removal assembly 303 for cleaning. The dust removal assembly 303 includes two brush rods 303b. The push rod 301 has symmetrically opened rectangular slots 303a. The two brush rods 303b are symmetrically rotated and inserted into the push rod 301, and are located within the two rectangular slots 303a. The push rod 301 has a first channel 303c and a second channel 303d, respectively. The first channel 303c communicates with the rectangular slots 303a. A vacuum pump 303e is located on one side of the push rod 301. An air suction pipe 303f and an air outlet pipe 303g are fixedly connected to the vacuum pump 303e. One end of the air suction pipe 303f is fixedly connected to the side wall of the push rod 301. The second channel 303d is connected. When the push rod 301 moves, the dust pump 303e can be activated to collect dust from the upper surface of the lower mold 102 and the bottom of the pressure rod 202c through the first channel 303c, the second channel 303d, the suction pipe 303f, and the exhaust pipe 303g. A transmission component 304 is provided between the moving component 302 and the dust removal component 303. The transmission component 304 includes an active transmission wheel 304a, which is fixedly connected to the rotating shaft 302c. A driven transmission wheel 304b is fixedly connected to the brush rod 303b. The driven transmission wheel 304b meshes with the active transmission wheel 304a, so that when the rotating shaft 302c rotates, it can drive the active transmission wheel 304a to rotate, which in turn drives the driven transmission wheel 304b to rotate, thus driving the brush rod 303b to rotate.

[0030] In use, the rotating shaft 302c rotates, driving the active transmission wheel 304a to rotate, which in turn drives the driven transmission wheel 304b to rotate, causing the brush rod 303b to rotate. When the push rod 301 moves, the brush rod 303b can sweep and clean the upper surface of the lower mold 102, the upper surface of the circular plate 203a, and the lower surface of the pressure rod 202c. At the same time, the pressure rod 202c rises to a height that is in contact with the upper surface of the push rod 301 under the action of the hydraulic telescopic rod 202a. Simultaneously, in conjunction with the dust pump 303e, the dust raised by the brush is collected through the first channel 303c, the second channel 303d, the suction pipe 303f, and the exhaust pipe 303g, achieving a cleaning effect.

[0031] Example 5 Reference Figures 7-12This invention provides a process for preparing rapidly disintegrating effervescent tablets, which uses an effervescent tablet press. The effervescent tablet press includes a cleaning unit 300, which includes a dust removal component 303. The dust removal component 303 also includes an inner rod 303h and a hollow brush rod 303b. The inner rod 303h is rotatably connected to the inner wall of the brush rod 303b. The brush rod 303b has multiple first openings 303i. The inner rod 303h has a cavity and a second opening 303j and a third opening 303k.

[0032] In use, because the cavity inside the inner rod 303h is located at the top, the center of gravity of the inner rod 303h is located at the bottom. This means that when the brush rod 303b rotates, the inner rod 303h does not rotate with the brush rod 303b. Through the cooperation of the first opening 303i, the third opening 303k, and the second opening 303j, when the brush rod 303b is in state one, the bristles on both sides of its upper and lower ends are in contact with the circular plate 203a, the surface of the lower mold 102, and the pressure rod 202c, forming a relatively sealed environment. The airflow is more concentrated through the two first openings 303i in the middle, which can better clean the surface of the circular plate 203a and the pressure rod 202c between the two bristles. When the brush rod 303b is in state two, air can be drawn from all around the brush rod 303b to suck up the dust around it. Through the dust suction in the two different states, the cleaning is more comprehensive.

[0033] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A process for the preparation of rapidly disintegrating effervescent tablets using an effervescent tablet press comprising a main unit (100), a compression unit (200), a cleaning unit (300) and a material conveying unit (400), characterized in that: The specific process when using the above effervescent tablet presser includes: S1, selecting citric acid, tartaric acid, and sodium bicarbonate as acid-base reaction components, selecting cross-linked povidone and microcrystalline cellulose as disintegration accelerators, and selecting mannitol as a soluble filler, drying all raw materials at 40-50°C for 2-4 hours, and controlling the water content to be ≤0.5%; S2, all raw materials are sieved through a 100-mesh sieve to obtain powders with uniform particle size; S3, the dried powders are mixed uniformly according to the formula proportion, a small amount of lubricant and flow aid are added at the end of mixing, and mixing is continued for 2-3 minutes; S4, the mixture is directly sent to the tablet press for tabletting; S5, immediately after tabletting, aluminum foil is used for sealing and packaging to prevent moisture absorption; The main unit (100) comprises an operating table (101), a lower mold (102) is fixedly arranged on the operating table (101), and a plurality of pressing grooves (103) are formed in the lower mold (102); The pressing unit (200) comprises a top plate (201) fixedly connected to the operating table (101), a tablet pressing assembly (202) is arranged on the top plate (201), and a material ejecting assembly (203) for ejecting effervescent tablets is arranged in the lower mold (102); The cleaning unit (300) comprises a push rod (301) slidably connected to the lower mold (102) in the left-right direction, a moving assembly (302) for moving is symmetrically arranged on the push rod (301), a dust removal assembly (303) for cleaning is arranged in the push rod (301), and a transmission assembly (304) is arranged between the moving assembly (302) and the dust removal assembly (303).

2. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 1, wherein: The tablet pressing assembly (202) comprises a hydraulic telescopic rod (202a) fixedly arranged on the top plate (201), an upper mold (202b) fixedly arranged at the bottom end of the hydraulic telescopic rod (202a), and a plurality of pressing rods (202c) fixedly connected to the bottom surface of the upper mold (202b).

3. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 2, wherein the said process comprises of: The material ejecting assembly (203) comprises a plurality of circular plates (203a) slidably connected to the inner wall of the pressing groove (103) in the up-down direction, a slot is formed in the bottom of the lower mold (102), a circular rod (203b) is fixedly connected to the bottom surface of the circular plate (203a) and extends into the slot, a bottom plate (203c) is fixedly connected to the bottom end of the circular rod (203b), and a plurality of electric telescopic rods (203d) are fixedly connected between the bottom surface of the bottom plate (203c) and the operating table (101) in a symmetrical manner.

4. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 3, wherein the said process comprises of: The material ejecting assembly (203) further comprises a rubber ring (203e) fixedly connected to the circular plate (203a), and the rubber ring (203e) is in close contact with the inner wall of the pressing groove (103).

5. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 4, wherein: The moving assembly (302) comprises a motor (302a), a moving plate (302b) is slidably connected to the side wall of the operating table (101) in the left-right direction, the motor (302a) is fixedly installed on the moving plate (302b), the output end of the motor (302a) is fixedly connected with a rotating shaft (302c), the rotating shaft (302c) is rotatably connected to the side wall of the push rod (301), the side wall of the lower mold (102) is fixedly connected with a toothed plate (302d), the rotating shaft (302c) is fixedly connected with a moving gear (302e), and the toothed plate (302d) is engaged with the moving gear (302e).

6. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 5 wherein: The dust removal assembly (303) comprises two brush rods (303b), the push rod (301) is symmetrically provided with a rectangular groove (303a), and the two brush rods (303b) are rotatably inserted into the push rod (301) and located in the two rectangular grooves (303a). The push rod (301) is respectively provided with a first channel (303c) and a second channel (303d), the first channel (303c) is communicated with the rectangular groove (303a), and the push rod (301) is provided with a dust collection pump (303e) on one side. The dust collection pump (303e) is respectively fixedly connected with a suction pipe (303f) and an air outlet pipe (303g), one end of the suction pipe (303f) is fixedly connected to the side wall of the push rod (301), and the suction pipe (303f) is communicated with the second channel (303d).

7. A process for the preparation of rapidly disintegrating effervescent tablets according to claim 6, characterized in that: The dust removal assembly (303) further comprises an inner rod (303h), the brush rod (303b) is hollow, the inner rod (303h) is rotatably connected to the inner wall of the brush rod (303b), a plurality of first openings (303i) are formed in the brush rod (303b), the inner rod (303h) is provided with a cavity, and the inner rod (303h) is respectively provided with a second opening (303j) and a third opening (303k).

8. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 7, wherein: The transmission assembly (304) comprises a driving wheel (304a), the driving wheel (304a) is fixedly connected to the rotating shaft (302c), the brush rod (303b) is fixedly connected with a driven wheel (304b), and the driven wheel (304b) is engaged with the driving wheel (304a).

9. A process for the preparation of rapidly disintegrating effervescent tablets according to claim 8, characterized in that: The material conveying unit (400) comprises a conveying device body (401), the conveying device body (401) is arranged on one side of the operating table (101), the lower mold (102) is fixedly connected with a guide plate (402), and the guide plate (402) extends above the conveying device body (401).

10. A process for the preparation of rapidly disintegrating effervescent tablets as claimed in claim 9, wherein the said process comprises of: The lower mold (102) is symmetrically and elastically slidably connected with a side plate (403), and the outer side wall of the side plate (403) is provided with an inclined surface.

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