Blood absorption retainer, retainer containing box and sample elution assembly

Abstract

The invention provides a blood absorption retainer, a retainer containing box and a sample elution assembly, the blood absorption retainer comprises a long-strip-shaped support, a connector is arranged at the front end of the support, a check block is arranged at the rear end of the support, and a moisture absorption head with a plurality of micropores is installed on the connector. The retainer accommodating box comprises an upper part and a lower part, and a plurality of partition plates are arranged at the lower part to form an accommodating space of the blood absorption retainer; the upper part comprises a left side cover and a right side cover which can be buckled together, and the left side cover and the right side cover are connected with the lower part through rotating shafts or connecting pieces. The blood absorption retainer is matched with the retainer accommodating box, so that rapid quantitative sampling of non-medical personnel can be realized, the sample can be remotely moved, and the device is suitable for remote medical industry application. The sample elution assembly comprises a pore plate and a retainer bracket which are matched for use, so that a large number of samples can be eluted at one time, and the sample elution assembly can be operated on a machine to improve the detection efficiency.

Description

Technical Field

[0001] This invention belongs to the field of testing equipment, and particularly relates to a blood absorption retainer, a retainer container, and a sample elution assembly. Background Technology

[0002] With the rapid development of computer and network communication technologies, telemedicine has emerged. Integrating medicine, computer science, and network communication technologies, it enables remote medical diagnosis and treatment, healthcare, medical training, and information services. This new medical model is a product of the combination of information technology and clinical medicine, breaking geographical limitations and saving doctors and patients significant time and money. Some remote diagnostic processes require blood sample collection and testing for more accurate disease assessment. Blood collection typically requires professional medical personnel, which limits the widespread application of telemedicine. However, some tests only require a small amount of blood and do not require liquid blood samples; dried blood samples can also meet the testing requirements. In such cases, if patients can collect samples themselves and have them delivered to the laboratory, sampling costs will be greatly reduced, and geographical limitations will not apply. Summary of the Invention

[0003] This invention addresses the technical problem of the lack of devices for patients to collect and transport small amounts of blood themselves in the prior art, and proposes a blood absorption holder, a holder container, and a sample elution assembly.

[0004] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0005] A blood absorption retainer includes an elongated support with a connector at the front end and a stop at the rear end. A moisture-absorbing head with several micropores is installed on the connector.

[0006] Preferably, the moisture-absorbing head is made of polyethylene or microporous ceramic.

[0007] Preferably, the absorbent head has a liquid absorption capacity of 10μl-60μl.

[0008] Preferably, the support is a hollow structure.

[0009] Preferably, the main absorption part is a cylindrical, cuboid, triangular prism, triangular pyramid, or column with wavy sidewalls.

[0010] Preferably, the support is cylindrical.

[0011] The present invention also proposes a retainer housing, comprising an upper part and a lower part. The lower part is provided with several partitions to form a housing space for the blood absorption retainer. The upper part consists of a left cover and a right cover that can be snapped together. Both the left cover and the right cover are connected to the lower part by a pivot or a connecting piece.

[0012] Preferably, the left and right covers are connected by snap-fit.

[0013] Preferably, the side walls of the left and right covers are provided with grooves, protrusions, or anti-slip textures.

[0014] The present invention also proposes a sample elution assembly, including a well plate and a retainer support. The well plate includes a well plate body with a plurality of elution fluid tanks for accommodating the blood absorption retainer as described in claim 1. The retainer support includes an upper support plate and legs extending downward from the upper support plate. The upper support plate has through holes corresponding to each elution fluid tank on the well plate. The diameter of the through holes is slightly larger than that of the blood absorption retainer support, so that the blood absorption retainer is suspended in the through holes of the support plate with its lower end located in the elution fluid tank. Clamping grooves are provided on both sides of the upper support plate, and positioning posts are provided at the lower ends of the legs.

[0015] Compared with the prior art, the advantages and positive effects of the present invention are as follows:

[0016] The blood absorption retainer described in this invention can quickly absorb a fixed amount of blood or other liquids, and can be operated by non-medical personnel, making it very convenient. When used with a retainer container, the blood absorption retainer can be transported to a testing laboratory for analysis via express delivery or other means, reducing sampling costs and eliminating geographical limitations, making it suitable for applications in the telemedicine industry.

[0017] The sample elution assembly, through the cooperation of the orifice plate and the retainer support, can elute a large number of samples at once. It can be operated in conjunction with a shaking elution instrument via the clamping groove and positioning column. The positioning column allows for positioning of the sample elution assembly, and the retainer support can be easily removed via the clamping groove after elution. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of the blood absorption retainer of the present invention;

[0019] Figure 2 This is an exploded view of the blood absorption retainer of the present invention;

[0020] Figure 3 This is a schematic diagram of the moisture-absorbing head structure of the blood absorption retainer of the present invention;

[0021] Figure 4 This is a schematic diagram of the structure of the retainer housing of the present invention;

[0022] Figure 5 This is a schematic diagram of the sample elution assembly of the present invention;

[0023] In the above figures: 1. Blood absorption retainer; 11. Support; 12. Connector; 13. Stop; 14. Moisture-absorbing head; 141. Mounting hole; 142. Main absorption section; 143. Arc-shaped protrusion; 2. Retainer housing box; 21. Upper part; 211. Left side cover; 212. Right side cover; 22. Lower part; 23. Connecting piece; 3. Orifice plate; 31. Orifice plate body; 32. Eluent tank; 4. Retainer support; 41. Upper support plate; 42. Support leg; 43. Through hole; 44. Clamping groove; 45. Positioning post; 46. Number. Detailed Implementation

[0024] To better understand the present invention, the following detailed description is provided in conjunction with the accompanying drawings and embodiments.

[0025] Example 1

[0026] like Figure 1 , Figure 2 As shown, a blood absorption retainer 1 is used for rapidly absorbing small amounts of blood or other liquid samples. Its structure includes a long, narrow support 11, the cross-section of which can be square, triangular, or circular. This embodiment uses a circular structure for easy compatibility with a standard 96-well plate 3. A connector 12 is provided at the front end of the support 11, and a moisture-absorbing head 14 with several micropores is mounted on the connector 12. The connector 12 is a thin, rod-shaped structure. One end of the moisture-absorbing head 14 has a mounting hole 141 through which it is inserted into the connector 12. The connector 12 can be hollow or solid. A stop 13 is provided on the outer wall of the rear end of the support 11. The stop 13 allows the blood absorption retainer 1 to be suspended on the 96-well plate 3 during elution, or it can be suspended on a collection device support frame.

[0027] The absorbent head 14, a key component for blood adsorption, is made of polyethylene or ceramic material and has numerous micropores inside, forming a capillary effect for rapid liquid absorption. Depending on the sampling requirements, the absorbent head 14 is available in different sizes, with liquid absorption capacities ranging from 10μl to 60μl, for example, including six sizes: 10μl, 20μl, 30μl, 40μl, 50μl, and 60μl. The absorbent head 14 includes a main absorption section 142, which can be cylindrical, cuboid, triangular prism, or triangular pyramidal, or alternatively, [the shape can be specified in the original text]. Figure 3 The column shown has a wavy sidewall, which increases the sidewall area and the number of micropores, thereby improving the absorption rate. The lower surface of the main absorption part 142 is provided with an arc-shaped protrusion 143, which facilitates contact with blood collection sites such as fingers for easy sampling.

[0028] After a patient's blood is sampled through the blood absorption retainer 1, it needs to be transferred to the laboratory for testing via express delivery or other means. Therefore, this embodiment also includes a retainer housing 2 specifically for transferring the aforementioned blood absorption retainer 1. Figure 4 As shown, the retainer housing 2 comprises an upper part 21 and a lower part 22. The inner wall of the lower part 22 is provided with several partitions, dividing the internal space into multiple small spaces, each capable of holding a blood absorption retainer 1. The upper part 21 is divided into two parts in the middle, forming a left cover 211 and a right cover 212 that can be fastened together. Both the left cover 211 and the right cover 212 are connected to the lower part 22 via a pivot or connecting piece 23. Applying force along the central seam to both sides can open the left cover 211 and the right cover 212 to the sides, thereby removing the blood absorption retainer 1 from the housing. Ventilation holes are provided on the left cover 211 and the right cover 212 to facilitate rapid drying of the absorbed blood.

[0029] To facilitate the fastening of the left cover 211 and the right cover 212, grooves and latches that engage within the grooves are provided on the surfaces where they contact each other. To facilitate the application of external force to open the left cover 211 and the right cover 212, two grooves or two anti-slip textured sections are provided on the outer sidewalls of the left cover 211 and the right cover 212. The covers can be opened by inserting fingers into the grooves and applying outward force, or by pressing down on the anti-slip texture and applying outward force. Alternatively, two baffles can be provided on the outer sidewalls of the left cover 211 and the right cover 212; opening the covers by prying the baffles outward will allow them to be opened.

[0030] Example 2

[0031] The present invention also proposes a sample elution assembly, including a perforated plate 3 and a retainer support 4, for eluting large quantities of sample adsorbed on the moisture-absorbing head 14 of the blood absorption retainer 1 described in Example 1 in a single step. Figure 5 As shown, the orifice plate 3 includes a rectangular orifice plate body 31. The orifice plate body 31 is provided with a plurality of eluent tanks 32 for accommodating the blood absorption retainer 1. The eluent tanks 32 extend vertically downwards from the upper surface of the orifice plate body 31, and the bottom of the tank is hemispherical. The plurality of eluent tanks are arranged in rows at equal intervals on the orifice plate body 31, and each row and each column is numbered 46 at its starting point. Preferably, the row numbers are marked with letters, and the column numbers are marked with numbers, allowing the location of each eluent tank 32 to be determined using the numbers and letters.

[0032] The retainer support 4 includes an upper support plate 41 and legs 42 extending downward from the upper support plate 41. The upper support plate 41 is provided with through holes 43 corresponding to each eluent tank 32 on the orifice plate 3. The starting end of each row and column of the through holes 43 is provided with a row number and column number consistent with the orifice plate 3 number 46. The diameter of the through holes 43 is larger than the support 11 of the blood absorption retainer 1, and can be prevented from falling by the stop block 13 of the blood absorption retainer 1, so that the blood absorption retainer 1 is suspended in the through holes 43 of the support plate and the lower end is located in the eluent tank 32. The moisture-absorbing head 14 is immersed in the eluent, which facilitates the elution of the dried blood sample on the moisture-absorbing head 14 into the eluent. The upper support plate 41 is provided with clamping grooves 44 on both sides, and the lower end of the support leg 42 is provided with a positioning post 45. The clamping grooves 44 and the positioning post 45 can be used in conjunction with the shaking elution instrument for operation. The positioning post 45 can be used to position the sample elution component. After elution, the retainer bracket 4 can be easily removed through the clamping grooves 44. The eluted blood absorption retainer 1 can be removed at once, and the eluent in the well plate 3 can be tested on the instrument.

[0033] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the protection scope of the present invention.

Claims

1. A blood absorption retainer, characterized in that: It includes a long strip-shaped support, with a connector at the front end and a stop at the rear end. A moisture-absorbing head with several micropores is installed on the connector.

2. The blood absorption retainer according to claim 1, characterized in that: The moisture-absorbing head is made of polyethylene or microporous ceramic.

3. The blood absorption retainer according to claim 1, characterized in that: The absorbent head has a liquid absorption capacity of 10μl-60μl.

4. The blood absorption retainer according to claim 1, characterized in that: The support structure is hollow.

5. The blood absorption retainer according to claim 1, characterized in that: The moisture-absorbing head includes a main absorption section, which is a cylindrical, cuboid, triangular prism, triangular pyramid, or column with wavy sidewalls. The lower surface of the main absorption section is provided with an arc-shaped protrusion.

6. The blood absorption retainer according to claim 1, characterized in that: The support is cylindrical.

7. A retainer housing, characterized in that: It consists of two parts, an upper part and a lower part. The lower part is equipped with several partitions to form a space for accommodating the blood absorption retainer. The upper part consists of a left cover and a right cover that can be snapped together. Both the left and right covers are connected to the lower part via a pivot or connecting piece.

8. The retainer housing according to claim 7, characterized in that: The left and right covers are connected by snap-fit.

9. The retainer housing according to claim 7, characterized in that: The side walls of the left and right covers are provided with grooves, protrusions, or anti-slip textures.

10. A sample elution assembly, characterized in that: The device includes an orifice plate and a retainer support. The orifice plate includes a main body with several elution tanks for accommodating the blood absorption retainer as described in claim 1. The retainer support includes an upper support plate and legs extending downward from the upper support plate. The upper support plate has through holes corresponding to each elution tank on the orifice plate. The diameter of the through holes is slightly larger than that of the blood absorption retainer support, so that the blood absorption retainer is suspended in the through holes of the support plate with its lower end located in the elution tank. Clamping grooves are provided on both sides of the upper support plate, and positioning posts are provided at the lower ends of the legs.

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