Sensitive skin repairing composition and application thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to a sensitive skin repairing composition and application thereof.The mask liquid is prepared from chamomile oil, tea tree oil, radix gentianae extract, centella asiatica extract, 4-tert-butyl cyclohexanol, butanediol, phosphatidyl ethanolamine and cardiolipin. Phosphatidyl ethanolamine ester is modified, the weight ratio of all the components is adjusted, all the components in the composition are coordinated to play the optimal functions of diminishing inflammation, resisting allergy, easing pain and repairing, exogenous stimulation, nerve stress response and inflammatory response are reduced, meanwhile, the self-protection mechanism is strengthened, the skin barrier is repaired, and the skin repairing effect is achieved. The composition disclosed by the invention is free from preservatives, natural and safe, so that the product is milder and does not generate side effects such as dependence and drug resistance after being used for a long time.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a sensitive skin repair composition and its application. Background Technology

[0002] Sensitive skin arises from a problem with the skin's natural defense system; the damaged lipid barrier renders it unable to withstand external stimuli. The lipid barrier is the skin's natural protective film, internally protecting the skin's moisture and acting as a barrier to keep it hydrated; externally, it prevents bacterial invasion, acting as a bactericide, bacteriostatic agent, and anti-infective agent. Therefore, once the lipid barrier is damaged, not only does its water-retention function decrease, causing dryness, itching, and even peeling, but its defense against cold, heat, and pressure also weakens, easily leading to redness and swelling. Sensitive skin requires special attention to basic skincare such as moisturizing, increasing skin hydration and strengthening the skin barrier function, which can greatly enhance the skin's resistance and reduce the irritation from external substances.

[0003] However, current skincare products prioritize high efficacy and rapid results, with active ingredients quickly penetrating the skin to reach deeper layers and produce significant effects. But since thin and damaged stratum corneum are major causes of sensitivity, highly effective and fast-acting skincare products can pose a higher risk of sensitivity for people with sensitive skin.

[0004] Chinese patent CN202011135445.2 discloses a composition, a facial mask liquid, and a facial mask for repairing sensitive skin. The composition for repairing sensitive skin includes the following components: Scutellaria baicalensis root extract, chamomile extract, agave extract, kava root extract, gentian extract, and centella asiatica extract. The facial mask liquid includes the following components: a sensitive skin repair composition, an auxiliary efficacy system, a thickening system, a moisturizing system, an oil system, a buffer system, a preservative system, and purified water. The mask sheet is preferably an aloe vera composite fiber mask sheet. This facial mask lacks a comprehensive understanding of the internal mechanisms of sensitive skin and cannot effectively promote the repair function of sensitive skin. Moreover, the preservative system may irritate the skin, increasing the risk of increased sensitivity.

[0005] Therefore, there is an urgent need for a preservative-free repairing composition for sensitive skin that can moisturize, repair the skin barrier, reduce inflammation, and regulate skin sensation while also providing effective repair for sensitive skin. Summary of the Invention

[0006] To address the shortcomings of the existing technology, this invention provides a sensitive skin repair composition and its application, which solves the problem that existing skin care products containing preservatives pose a higher risk of sensitivity to people with sensitive skin. It achieves comprehensive treatment of the internal mechanisms of sensitive skin while moisturizing, repairing the skin barrier, reducing inflammation and regulating skin sensation, effectively forming a repair function for sensitive skin.

[0007] The specific technical solution of the present invention is as follows: The purpose of this invention is to provide a sensitive skin repair composition and its application. The sensitive skin repair composition comprises the following components by weight percentage: Chamomile oil 20-40%, tea tree oil 10-20%, gentian extract 10-40%, centella asiatica extract 10-20%, 4-tert-butylcyclohexanol 5-10%, butylene glycol 10-30%, conditioning agent 5-10%, water balance.

[0008] Chamomile oil is extracted from the flowers of the chamomile plant using methods such as steam distillation. It has antibacterial, antioxidant, anti-inflammatory, soothing, and anti-allergic bioactivities. It can inhibit induced allergies in the skin, enhance the resistance of capillaries, and inhibit capillary permeability to have anti-inflammatory effects. It has good applications in calming, soothing, and relieving pain.

[0009] Tea tree oil is an essential oil extracted from fresh leaves and tender branches. It contains a wealth of chemical components, the main active ingredients of which include terpinen-1-ol-4, 1-8-cineole, α-terpinene, γ-terpinene, etc. These components endow tea tree oil with a wide range of effects such as broad-spectrum antimicrobial activity, antibacterial, anti-inflammatory, insecticidal and acaricidal properties, as well as the ability to promote wound healing.

[0010] Gentian is a perennial herb of the Gentianaceae family. Gentian extract mainly works by inhibiting and reducing inflammatory responses, achieving anti-allergic and anti-irritant effects, and has certain antipruritic, anti-swelling, anti-inflammatory, and analgesic effects.

[0011] Centella asiatica is the whole herb of Centella asiatica, a plant in the Apiaceae family. The active ingredients in Centella asiatica extract are asiaticoside and hydroxyasiaticoside, which have excellent repair effects, such as scar repair, dermal repair and sunburn repair, helping to repair damaged skin and promoting smooth and delicate skin.

[0012] 4-tert-butylcyclohexanol interacts with other components in the system to rapidly relieve the neurosensory activity of sensitive skin symptoms, reducing burning and stinging sensations; it helps alleviate excessive skin reactions and reduce sensitivity symptoms.

[0013] The conditioning agents in this invention are components that can condition the skin and coordinate the functions of various components in the composition. The conditioning agents include phosphatidyl and ethanolamine cardiolipin.

[0014] Furthermore, the weight ratio of chamomile oil to tea tree oil is (1.5–2.5):1.

[0015] Preferably, the weight ratio of chamomile oil to tea tree oil is 2:1.

[0016] Furthermore, the content of gentian extract and centella asiatica extract is not less than 30 wt% of the total mass of chamomile oil and tea tree oil.

[0017] Preferably, the gentian extract accounts for 35 wt% of the total mass of chamomile oil and tea tree oil, and the centella asiatica extract accounts for 42 wt% of the total mass of chamomile oil and tea tree oil.

[0018] Furthermore, the weight ratio of phosphatidylethanolamine to cardiolipin is (2-3):1.

[0019] Preferably, the weight ratio of phosphatidylethanolamine to cardiolipin is 2.4:1.

[0020] The applicant discovered that adjusting the weight ratio of chamomile oil to tea tree oil significantly improved the anti-allergic effect of the composition, significantly reduced the irritation of sensitive skin to lactic acid and other substances, reduced stinging sensation, and achieved a better anti-allergic and soothing effect. Chamomile oil contains components such as bisabolene, α-dienone, and linalool, which have good intermolecular forces such as hydrogen bonds with the active ingredients of tea tree oil. These forces can promote each other and accelerate the penetration of active ingredients into the skin. Simultaneously, it can reduce the expression of inflammatory factors such as interleukin-1 and leukotrienes in the skin, inhibit the occurrence of inflammatory responses, and prevent these inflammatory factors from damaging the skin barrier. This helps to alleviate allergic inflammation such as redness, stinging, and itching caused by external stimuli in sensitive skin, while accelerating the skin's healing process. Moreover, the anti-allergic effect of the composition is most significant when the weight ratio of chamomile oil to tea tree oil is 2:1; when the weight ratio changes significantly, the anti-allergic effect of the composition decreases significantly. This may be because the synergistic effect between chamomile oil and tea tree oil reaches the best balance when the weight ratio is 2:1, which can best promote the efficacy of the components in the system. When the weight ratio changes, it will cause the interaction between them to be disrupted, thus affecting the effect.

[0021] In the process of developing this invention, the applicant discovered a close correlation between the content of gentian extract and centella asiatica extract in the composition and the content of chamomile oil and tea tree oil. When the ratio of their contents is within a certain range, the anti-allergic effect of the composition can be significantly improved. However, when the content of gentian extract and centella asiatica extract is too low or too high, the anti-allergic effect of the composition will be affected. Gentian extract is rich in glycosides with specific structures, and centella asiatica extract is rich in triterpenoids with specific structures, such as gentiocarbazone and asiatic acid. These bioactive components can, to a certain extent, promote the expression of filaggrin and cysteine-aspartate specific protease-14 in corneal cells. These factors help promote the connection between keratin fibers, maintain the flattened state of keratinocytes to form a keratin film, and also participate in the terminal differentiation of keratinocytes, assisting filaggrin in forming a complete stratum corneum, thus thickening the stratum corneum, thereby improving the skin barrier and reducing sensitivity to external factors.

[0022] The applicant discovered that using phosphatidylethanolamine and cardiolipin in a certain proportion as conditioning agents in this invention can significantly improve the stability of the composition, enabling it to maintain good storage performance at both higher and lower temperatures. This effectively avoids instability issues such as stratification and precipitation during storage under different environments, especially when the weight ratio of lecithin to dipalmitoylphosphatidylcholine is 2.4:1, the effect is most significant. This may be because cardiolipin has a hydrophilic head and two hydrophobic tails, exhibiting both hydrophilic and hydrophobic properties, while phosphatidylethanolamine also possesses both hydrophobic and hydrophilic groups, forming a bilayer micelle structure under the influence of the components in the composition system. Due to the structural differences between phosphatidylethanolamine and cardiolipin, the micelles they form also differ. These different micelles in the system can encapsulate the different highly active components in the system, such as 4-tert-butylcyclohexanol, chamomile oil, tea tree oil, gentian extract, and centella asiatica extract, within the formed micelles. This prevents the components from deteriorating under the stimulation of external light, bacteria, and other components, as well as from phase separation, precipitation, and other unstable conditions during storage.

[0023] To further improve the stability and antibacterial effect of the composition, the applicant found that modifying phosphatidylethanolamine can better improve the performance of the composition. The specific operation method for preparing modified phosphatidylethanolamine is as follows: S11: Add phosphatidylethanolamine ester and n-hexane to the reaction flask, and disperse by ultrasonication at a frequency of 40-60 kHz for 5-10 min, then heat to 40-50 °C. S12: Add sodium hypochlorite at 10%–20% of the mass of phosphatidylethanolamine to the mixture obtained in step S11, stir evenly, then slowly add acetic acid at 30%–40% of the mass of phosphatidylethanolamine, adjust the pH to 3.5–4.5, carry out the reaction, and discharge the material after the reaction is completed. S13: Add the material obtained in step S12 to a nano-carboxy chitosan solution with a mass concentration of 0.1-0.2%, and add 0.1 mol / L HCl solution dropwise to control the pH value to 4-4.5. Stir the reaction at 35-45℃ for 1.0-3.0 h, separate the material, and obtain modified phosphatidylethanolamine ester by washing and freeze drying.

[0024] Chitosan, a commonly used organic antibacterial agent, is widely used in the cosmetics industry due to its wide availability, renewability, biocompatibility, non-toxicity, non-irritation, high and long-lasting antibacterial activity, broad antibacterial spectrum, and safety. Furthermore, chitosan can be directly added to cosmetic formulations as a moisturizer, thickener, or stabilizer. Its excellent safety and biocompatibility not only improve the user experience but also extend shelf life. In this invention, after aldehyde-modifying the double bond sites of phosphatidylethanolamine ester, nano-carboxylated chitosan is grafted in situ onto the phosphatidylethanolamine ester. The resulting modified phosphatidylethanolamine better improves the stability and antibacterial effect of the composition, extending the product's shelf life without the need for additional preservatives.

[0025] Furthermore, the applicant discovered that the improvement in composition stability by the conditioning agent composed of the aforementioned specific components is also related to the presence of chamomile oil and tea tree oil in the system. When the content of chamomile oil or tea tree oil is excessive, or when a certain component is missing, its stability is significantly affected. This may be due to the presence of alkyl chains of a certain length in the components, allowing these components to randomly interweave within the micelles formed by the conditioning agent, reducing the influence of the micelles on external stimuli, thereby contributing to further improvement in micelle stability. Simultaneously, the applicant unexpectedly discovered that adjusting the conditioning agent components and the content of chamomile oil and tea tree oil can significantly improve the anti-allergic effect of the composition. This may be due to the interaction between the different structural micelles formed by the conditioning agent, which can encapsulate and gradually and slowly release the remaining components in the system, promoting the formation of mantle proteins, tight junction proteins, etc., and inhibiting the expression of pro-inflammatory factors, thereby contributing to improved anti-allergic effects.

[0026] The sensitive skin repair composition of the present invention proposes a comprehensive response mechanism for sensitive skin repair: while providing external defense and reducing exogenous irritants and allergens, it also provides internal anti-inflammatory and soothing effects, reducing nerve stress and inflammatory responses, and further strengthens its own protective mechanisms, repairs the skin barrier, and enhances oxidative stress resistance.

[0027] A second aspect of the present invention provides the application of the sensitive skin repair composition as described above, in the field of skincare technology.

[0028] As a preferred technical solution, the skin care products include face cream, eye cream, facial cleanser, face mask, BB cream, serum, sunscreen, sunscreen water, facial cleanser, facial cleanser lotion, acne lotion, essential oil, moisturizing water, toner, astringent water, and softening lotion.

[0029] The beneficial effects of this invention are as follows: This invention provides a sensitive skin repair composition and its application. The sensitive skin repair composition includes the following components: chamomile oil, tea tree oil, gentian extract, centella asiatica extract, 4-tert-butylcyclohexanol, butylene glycol, phosphatidylethanolamine, and cardiolipin. By modifying phosphatidylethanolamine ester and adjusting the weight ratio of lecithin and dipalmitoylphosphatidylcholine to 2.8:1 and the weight ratio of chamomile oil and tea tree oil to 2:1, the components in the composition are coordinated to exert optimal anti-inflammatory, anti-allergic, analgesic, and repair functions. While reducing exogenous stimulation, nerve stress response, and inflammatory response, it strengthens the skin's own protective mechanism, repairs the skin barrier, and further enhances oxidative stress resistance. Moreover, this invention does not contain any additional preservatives, making it natural and safe, resulting in a gentler and non-irritating product. Long-term use will not produce side effects such as dependence or drug resistance. It also has superior high and low temperature stability, allowing it to be stored for a long time in harsh environments without deterioration or inactivation. Detailed Implementation

[0030] The present invention will be further described below with reference to embodiments, but this does not limit the invention. Unless otherwise specified, the experimental methods in the following embodiments are conventional methods.

[0031] A sensitive skin repair composition comprises, by weight percentage, the following components: Chamomile oil 20-40%, tea tree oil 10-20%, gentian extract 10-40%, centella asiatica extract 10-20%, 4-tert-butylcyclohexanol 5-10%, butylene glycol 10-30%, conditioning agent 5-10%, water balance.

[0032] Gentian extract accounted for 35 wt% of the total mass of chamomile oil and tea tree oil, and centella asiatica extract accounted for 42 wt% of the total mass of chamomile oil and tea tree oil.

[0033] The conditioning agents include phosphatidyl and ethanolamine cardiolipin in a weight ratio of 2.4:1.

[0034] The preparation method of the modified phosphatidylethanolamine ester in this invention is as follows: S11: Add phosphatidylethanolamine ester and n-hexane to the reaction flask, and disperse by ultrasonication at a frequency of 40-60 kHz for 5-10 min, then heat to 40-50 °C. S12: Add sodium hypochlorite at 10%–20% of the mass of phosphatidylethanolamine to the mixture obtained in step S11, stir evenly, then slowly add acetic acid at 30%–40% of the mass of phosphatidylethanolamine, adjust the pH to 3.5–4.5, carry out the reaction, and discharge the material after the reaction is completed. S13: Add the material obtained in step S12 to a nano-carboxy chitosan solution with a mass concentration of 0.1-0.2%, and add 0.1 mol / L HCl solution dropwise to control the pH value to 4-4.5. Stir the reaction at 35-45℃ for 1.0-3.0 h, separate the material, and obtain modified phosphatidylethanolamine ester by washing and freeze drying.

[0035] The application of the sensitive skin repair composition described above is within the field of skincare technology.

[0036] As a preferred technical solution, the skin care products include face cream, eye cream, facial cleanser, face mask, BB cream, serum, sunscreen, sunscreen water, facial cleanser, facial cleanser lotion, acne lotion, essential oil, moisturizing water, toner, astringent water, and softening lotion.

[0037] Examples 1-4 and Comparative Examples 1-4 The repair compositions of Examples 1-4 and Comparative Examples 1-4 were prepared according to the formulations in Table 1 below.

[0038] Table 1: Formulation composition of Examples 1-4 and Comparative Examples 1-4, by weight percentage Effect Experiment: 1. Evaluation of moisturizing and hydrating effects The moisturizing and hydrating effects of products were evaluated by testing skin moisture content and water loss. During the skin moisture content and water loss measurement and evaluation process, indoor relative humidity and temperature were controlled. A total of 80 subjects, aged 20-55 years, were included.

[0039] (1) Moisturizing and hydrating efficacy test of the composition under dry environment (ambient humidity 37%): Moisture content was tested using the CORNEOMETER capacitance method. The results were expressed as the rate of change of the set Moisture Measurement Value (MMV). Skin moisture content was measured in subjects 2, 4, 8, 12, and 24 hours after product use. The experimental instrument was a Corneometer CM825 (CK GmbH, Germany). The formula for calculating the rate of change in moisture content (%) was: Moisture content change rate (%) = (Tn - T0) / T0 * 100, where T0 is the skin basal data collection value at the last moment; Tn is the data collection value of the sample group at each time point. A higher rate of change in moisture content indicates a more significant moisturizing effect. The results are shown in Table 2.

[0040] Table 2: Change rate of facial moisture content in Examples 1-3 and Comparative Examples 1-5 (ambient humidity 37%) As shown in Table 2, the present invention achieves a more prominent synergistic and long-lasting moisturizing effect by adding chamomile oil and tea tree oil to the composition system. Furthermore, the addition of gentian extract and centella asiatica extract can enhance the synergistic and long-lasting moisturizing effect of the chamomile oil and tea tree oil system to a certain extent.

[0041] (2) Water Loss Test: Based on the diffusion principle discovered by A. Fick, the change in water vapor pressure on the adjacent skin surface was measured to assess the loss of skin surface moisture. Water loss was expressed as TEWL (Trans-Epidermal Water Loss), with units of g / hm2. The lower the value, the more significant the effect of the sample in preventing water loss and the more complete the skin barrier function. The change rate of skin water loss was measured after 1h, 4h, 8h and 24h of use of the composition sample by the subjects. The experimental instrument was: Tewameter TM300, CK GmbH, Germany. The formula for calculating the change rate of skin water loss was: Change rate of water loss % = (Tn-T0) / T0*100, where: T0 is the data collection value of the skin base when no sample was applied; Tn is the data collection value of the sample group at each time point. The lower the negative value of the change rate of water loss, the more significant the water-locking effect. The results are shown in Table 3.

[0042] Table 3: Change rate of facial moisture loss in Examples 1-3 and Comparative Examples 1-5 (ambient humidity 37%) As shown in Table 3, the chamomile oil, tea tree oil, gentian extract, and centella asiatica extract added to the composition system of this invention have a synergistic and long-lasting water-locking function, and with the synergistic effect of 5-10% 4-tert-butylcyclohexanol, 10-30% butylene glycol, and conditioning agent, the long-lasting water-locking ability is even stronger. The synergistic skin repair function of chamomile oil, tea tree oil, gentian extract, centella asiatica extract, 5-10% 4-tert-butylcyclohexanol, 10-30% butylene glycol, and conditioning agent of this invention can also effectively establish a sound skin barrier function. This is mainly reflected in the fact that the water-locking effect of Comparative Example 1 is significantly reduced after the loss of chamomile oil, which is caused by the disruption of the synergistic effect between chamomile oil and tea tree oil. The chamomile oil and tea tree oil of this invention have a synergistic ability to reduce water loss, and with the cooperation of the entire composition system, the ability to inhibit water loss is more prominent, and it also has a certain moisturizing effect.

[0043] 2. Evaluation of Repair Effect Test participants: 80 test subjects with dry or red facial skin were randomly divided into 8 groups of 10 people each; Group a used the formulation product of Example 1, Group b used the formulation product of Example 2, Group c used the formulation product of Example 3, Group d used the formulation product of Comparative Example 1, Group e used the formulation product of Comparative Example 2, Group f used the formulation product of Comparative Example 3, Group g used the formulation product of Comparative Example 4, and Group h used the formulation product of Comparative Example 5.

[0044] Test area: face Usage: After 40 days of use, a comprehensive evaluation will be conducted. The evaluation results will be based on the improvement of dry or red facial skin, and will be divided into excellent effect, good effect, average effect, and no effect.

[0045] Evaluation method: Questionnaire completion; The overall evaluation of the test results is shown in Table 4 below.

[0046] Table 4: Summary Table of Product Trial and Repair Effect Evaluation for Group AH 3. Evaluation of the degree of sensitivity to lactic acid stimulation The composition samples in Examples 1-3 and Comparative Examples 1-5 were subjected to facial lactic acid stimulation efficacy evaluation tests to observe the changes in the sensitivity of the participants' faces to lactic acid stimulation before and after using the above composition samples.

[0047] The specific testing and evaluation method is as follows: Eighty individuals with sensitive skin aged 21-39 were invited, and samples from each embodiment were randomly assigned to groups of 10 for use. During the experiment, a half-face test was conducted using a randomization table. The left side of each subject's face was applied with the composition sample from the above embodiment, while the right side was wiped clean with water. The nasolabial fold area was selected for the test. Test method: 50µl of a 12wt% lactic acid solution was taken and dropped onto a 1.0cm diameter single-layer filter paper. The filter paper was then placed on the subject's face where the sample was applied. The subject was asked about stinging sensations after 3 minutes, and a 4-point scale was used for scoring (0 for no stinging, 1 for mild stinging, 2 for moderate stinging, and 3 for severe stinging). The subject's score was recorded as the initial lactic acid stimulation score W0 for that side. After the test, the subjects were required to use the distributed composition sample as instructed, specifically once every evening, applying the composition sample to the left side of the face and wiping the right side clean with water, for four consecutive weeks. Follow-up visits were required on days 14 and 28 of the experiment. Under the same testing environment, the lactate stimulation scores W14 and W28 of the subjects were tested and recorded. The experimental results were taken as the average of each group (actual effective number of people), and the evaluation results are shown in Table 5 below.

[0048] Table 5. Results of Anti-sensitivity Test 4. Stability Evaluation The stability of the compositions in Examples 1-3 and Comparative Examples 1-5 was tested, and the specific test methods are as follows: Heat resistance test: Place the sample in an electric thermostatic incubator at (40±1)℃ for 24 hours. After returning to room temperature, observe whether there are phenomena such as thinning, discoloration, layering and hardness changes to judge the heat resistance of the sample. Rating is 1 to 3, with grade 1 being the best heat resistance and grade 3 being the worst. Cold resistance test: The samples were placed in a refrigerator at (-10)℃±1℃ for 24 hours. After returning to room temperature, the samples were observed for phenomena such as thinning, discoloration, layering, and changes in hardness to determine their cold resistance performance. The samples were rated from 1 to 3, with 1 being the most stable and 3 being the least stable. The results are shown in Table 6 below.

[0049] Table 6 Performance Test Results As can be seen from the above experimental results, the sensitive skin repair composition of the present invention uses plant ingredients such as chamomile oil, tea tree oil, gentian extract, and centella asiatica extract, as well as phosphatidylcholine and modified ethanolamine cardiolipin. Utilizing the interaction between these specific ingredients, the composition synergistically improves the sensitive skin barrier, relieves pain, absorbs heat and reduces swelling, and quickly eliminates allergy symptoms. Furthermore, through the ingenious combination of specific components and the regulation of their content, the composition coordinates the various components to exert optimal anti-inflammatory, anti-allergic, analgesic, and repairing functions. While reducing exogenous stimuli, nerve stress responses, and inflammatory responses, it strengthens the body's own protective mechanisms, repairs the skin barrier, and further enhances oxidative stress resistance. At the same time, the composition possesses superior high and low temperature stability, enabling the product to be stored for a long time in harsh environments without deterioration or inactivation. It is preservative-free, naturally safe, and makes the product more gentle and non-irritating. Long-term use will not produce side effects such as dependence or drug resistance.

[0050] This invention is not limited to the optional embodiments described above, and anyone can derive other various forms of products based on the inspiration of this invention. The specific embodiments described above should not be construed as limiting the scope of protection of this invention; the scope of protection of this invention should be determined by the claims, and the specification can be used to interpret the claims.

Claims

1. A sensitive skin repair composition, characterized in that, The sensitive skin repair composition comprises the following components by weight percentage: 20-40% chamomile oil, 10-20% tea tree oil, 10-40% gentian extract, 10-20% centella asiatica extract, 5-10% 4-tert-butylcyclohexanol, 10-30% butylene glycol, 5-10% conditioning agent, and water as the balance.

2. The sensitive skin repair composition according to claim 1, characterized in that, The conditioning agent includes phosphatidyl and ethanolamine cardiolipin, with the ethanolamine cardiolipin undergoing modification treatment.

3. The sensitive skin repair composition according to claim 2, characterized in that, The modified phosphatidylethanolamine is prepared as follows: S11: Add phosphatidylethanolamine ester and n-hexane to the reaction flask, and disperse by ultrasonication at a frequency of 40-60 kHz for 5-10 min, then heat to 40-50 °C. S12: Add sodium hypochlorite at 10%–20% of the mass of phosphatidylethanolamine to the mixture obtained in step S11, stir evenly, then slowly add acetic acid at 30%–40% of the mass of phosphatidylethanolamine, adjust the pH to 3.5–4.5, carry out the reaction, and discharge the material after the reaction is completed. S13: Add the material obtained in step S12 to a nano-carboxy chitosan solution with a mass concentration of 0.1-0.2%, and add 0.1 mol / L HCl solution dropwise to control the pH value to 4-4.

5. Stir the reaction at 35-45℃ for 1.0-3.0 h, separate the material, and obtain modified phosphatidylethanolamine ester by washing and freeze drying.

4. The sensitive skin repair composition according to claim 1, characterized in that, The weight ratio of chamomile oil to tea tree oil is 2:

1.

5. The sensitive skin repair composition according to claim 1, characterized in that, The weight ratio of phosphatidylethanolamine to cardiolipin is 2.4:

1.

6. The sensitive skin repair composition according to claim 1, characterized in that, The sensitive skin repair composition is applied in the field of skin care technology, including face cream, eye cream, facial cleanser, face mask, BB cream, serum, sunscreen, sunscreen water, facial cleanser, facial cleanser lotion, acne lotion, essential oil, moisturizing water, toner, astringent water, and softening lotion.

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