Intelligent electric dosing device applied to pressure quantitative aerosol

Abstract

The invention discloses an intelligent electric dosing device applied to a pressure quantitative aerosol, and aims to solve the problems of difficulty in hand-mouth coordination and low medicine utilization rate in use of the traditional pressure quantitative aerosol (pMDI). The device comprises a shell, a mouthpiece, a medicine bottle fixing mechanism, an electric driving mechanism, an air suction detection module and a control module. The medicine bottle fixing mechanism is movably arranged on the shell and used for fixing a medicine bottle in a repeatable assembling and disassembling mode and enabling a medicine bottle nozzle to be aligned with and stretch into an air inlet of the mouthpiece. The electric driving mechanism is used for driving the medicine bottle fixing mechanism to move to extrude the nozzle to release medicine; the inspiration detection module is used for detecting the inspiration action of a patient; the control module automatically controls the electric driving mechanism to execute pesticide spraying according to the air suction signal. By means of an air suction synchronous automatic triggering mechanism, the medicine taking correctness and the medicine lung deposition rate are remarkably improved.

Description

Technical Field

[0001] This invention relates to the field of aerosol drug delivery, and in particular to an intelligent electric drug delivery device for pressurized metered aerosols. Background Technology

[0002] A pressurized metered-dose inhaler (pMDI) is a drug delivery device that encapsulates the drug and propellant in a pressure-resistant container. Controlled by a metering valve system, the drug is expelled in a mist form using the pressure of the propellant. Due to its advantages such as portability, accurate dosage, and rapid onset of action, it has become one of the mainstream methods of drug delivery for respiratory diseases such as asthma and chronic obstructive pulmonary disease. However, traditional pMDIs have a significant limitation in clinical use: their effective use depends on the patient's hand-mouth coordination. Specifically, the correct procedure requires the patient to first exhale slowly and deeply, then place the mouthpiece in their mouth, and simultaneously begin a slow, deep inhalation while immediately pressing the bottom of the canister to trigger the spray. After spraying, the patient should continue inhaling and hold their breath for a few seconds. The coordination of this series of actions directly affects the drug deposition efficiency in the lungs. If the timing of pressing is not synchronized with the inhalation process—for example, spraying at the beginning, end, or during breath-holding—a large amount of drug will be deposited in the mouth, throat, or air, reducing the proportion of medication delivered to the lungs and affecting the therapeutic effect. This coordination requirement is particularly difficult to achieve for children, the elderly, or patients in the acute phase, often leading to medication errors, poor efficacy, and decreased patient compliance. Summary of the Invention

[0003] The present invention aims to at least solve one of the technical problems existing in the prior art. Therefore, one object of the present invention is to provide an intelligent electric drug delivery device for pressurized metered-dose aerosols. The technical solution of the present invention is as follows: A smart electric drug delivery device for pressurized metered-dose aerosols, comprising: case; The mouthpiece is disposed on the housing, and the mouthpiece has a spray channel inside for the patient to inhale, and the mouthpiece has an air inlet communicating with the spray channel; A bottle fixing mechanism is movably mounted on the housing and located on one side of the air inlet. The bottle fixing mechanism is used to fix the pressurized metered aerosol bottle in a removable manner and to align the nozzle of the bottle with and extend it into the air inlet. The bottle fixing mechanism is configured to move relative to the housing to drive the fixed bottle to squeeze the nozzle, thereby releasing the medicine spray into the spray channel. An electric drive mechanism is provided on the housing and is connected to the medicine bottle fixing mechanism to drive the medicine bottle fixing mechanism to move under control. An inhalation detection module is disposed inside the mouthpiece. The inhalation detection module is used to detect the patient's inhalation action through the mouthpiece and generate a corresponding detection signal. The control module is electrically connected to the inhalation detection module and the electric drive mechanism respectively. The control module is configured to automatically control the electric drive mechanism when the detection signal reaches a preset condition, so as to drive the medicine bottle fixing mechanism to perform a movement action to release medicine spray. Furthermore, the medicine bottle fixing mechanism is equipped with a pressing element that can be manually pressed; The pressing element is configured to, in response to manual pressing pressure applied by the user, directly drive the medicine bottle fixing mechanism to perform a movement action that releases the medicine spray, independent of the electric drive mechanism. Furthermore, the medicine bottle fixing mechanism includes a drive frame, a pressing mechanism, and a clamping mechanism; The clamping mechanism is movably disposed within the housing for detachably clamping and fixing the medicine bottle. A first elastic element is provided between the clamping mechanism and the housing, which provides an elastic force to reset the clamping mechanism after it moves. The drive frame is movably disposed within the housing, and the electric drive mechanism is connected to the drive frame to drive the drive frame to move; The pressing mechanism is connected between the drive frame and the clamping mechanism. The pressing mechanism is provided with the pressing element. The pressing mechanism is driven by the drive frame or manually driven by the pressing element, thereby driving the clamping mechanism to move. A second elastic element is provided between the pressing mechanism and the housing, the second elastic element being used to provide an elastic force to reset the pressing mechanism after it moves. Furthermore, the clamping mechanism includes a clamping seat, a clamp, and a third elastic element; The clamping seat defines a clamping cavity for accommodating the medicine bottle, and the clamp is movably disposed in the clamping cavity. The clamp is configured to hold the bottleneck of the medicine bottle. A third elastic member is provided between the clamp and the clamping seat. The third elastic member is used to drive the clamp to move outward to release the medicine bottle under normal conditions. The pressing mechanism is detachably connected to the drive frame; When the pressing mechanism is installed on the drive frame, the pressing mechanism is used to drive the clamp to move inward to lock the medicine bottle; When the pressing mechanism is removed, the third elastic element drives the clamp to reset outward to release the medicine bottle. Furthermore, the pressing mechanism includes a pressing cover and a ring sleeve; The pressing cover is detachably connected to the drive frame, and the ring sleeve is located between the pressing cover and the clamping seat; The ring is used to be fitted onto the medicine bottle. The ring is axially movable relative to the housing and a second elastic element is provided between the ring and the housing. A pressure rod is provided at one end of the ring facing the clamping seat, and a first extrusion slope is provided on the pressure rod. The clamping seat is provided with a clearance hole communicating with the clamping cavity, and the clamp is provided with a second pressing slope; the pressure rod extends into the clearance hole, and the first pressing slope cooperates with the second pressing slope; When the press cap is installed on the drive frame, the press cap drives the ring to move toward the clamping seat, and the first pressing slope presses the second pressing slope to drive the clamp to move inward and clamp the medicine bottle. Furthermore, the drive frame includes a fixed ring and a connecting rod. The fixed ring is used for the medicine bottle to pass through, and the connecting rod is provided on the fixed ring. The connecting rod is connected to the electric drive mechanism, and the pressing cap is rotatably and detachably connected to the fixed ring. The inner edge of the fixing ring is provided with a first anti-detachment rib, and the outer edge of the pressing cover is provided with a second anti-detachment rib. When the press cover is rotated in the forward direction, the second anti-detachment rib can be screwed in and engaged below the first anti-detachment rib. Rotating the press cover in the reverse direction can separate the second anti-detachment rib from the first anti-detachment rib. Furthermore, the press cover is a cylindrical structure with one end open and the other end closed, and the outer edge of the open end of the press cover is provided with the second anti-detachment rib; When the press cap is installed on the fixing ring, the press cap covers the outside of the medicine bottle, and the closed end of the press cap extends outward from the fixing ring to form the press element. Furthermore, the drive frame also includes a connecting frame connected to the connecting rod, and the connecting frame is provided with a shaft hole; The electric drive mechanism includes a motor, a reducer, and an eccentric gear set. The eccentric gear set includes a housing, a first output shaft, a first eccentric gear, a second output shaft, and a second eccentric gear. The housing contains a first eccentric gear and a second eccentric gear that mesh with each other. The first eccentric gear is connected to the first output shaft, and the second eccentric gear is connected to the second output shaft. The motor is connected to the first output shaft through the reducer, and the second output shaft is rotatably inserted into the shaft hole. Furthermore, the intake detection module is a pressure sensor, and a baffle is provided inside the airflow channel to reduce the cross-sectional area of ​​the airflow channel, with the pressure sensor located at the baffle. Furthermore, the control module includes: A power module is provided to supply power to the various units inside the electric drive mechanism, the intake detection module, and the control module. The display module is used to display device status information; A voice module, wherein the voice module is used to provide voice prompts; An attitude sensor module is provided for detecting attitude changes of the drug delivery device during use. The main controller is electrically connected to the power module, display module, voice module, attitude sensor module, inhalation detection module, and electric drive mechanism. The main controller is used to control the operation of the display module, voice module, and electric drive mechanism based on the signals from the inhalation detection module and / or attitude sensor module. Compared with the prior art, the beneficial effects of the present invention are as follows: 1. Intelligent Synchronous Trigger: Through highly sensitive inhalation detection and rapid response control, the drug release and the patient's inhalation process are automatically and accurately synchronized, fundamentally solving the hand-mouth coordination problem of traditional pMDI and improving the efficiency of drug deposition in the lungs. 2. Dual-mode drive protection: It integrates two independent systems, a fully automatic electric drive and a purely mechanical manual drive, providing a redundant safety mechanism to ensure reliable drug delivery under any circumstances. 3. Adaptive and stable clamping: Adopting an innovative inclined plane driven radial locking mechanism, it can achieve quick assembly and disassembly. Combined with the cylindrical press cap, it can firmly clamp standard pMDI medicine bottles of various sizes, making it highly versatile and easy to use. 4. Compact and reliable structure: It adopts an eccentric gear and other efficient transmission and reset mechanism to accurately convert rotational power into linear pressing action. The structure is compact and the operation is stable, ensuring the consistency and accuracy of drug administration. 5. Intelligent medication guidance: Built-in posture sensor and interaction module can monitor medication posture and guide users to operate correctly through visual and voice feedback, improving treatment compliance and effectiveness. Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention, and the drawings are only examples and not strictly drawn to scale. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort: Figure 1 This is an overall sectional view of the present invention; Figure 2 This is a cross-sectional view of the mouthpiece portion of the present invention; Figure 3 This is a cross-sectional view of the medicine bottle fixing mechanism of the present invention; Figure 4 This is a schematic diagram of the drive frame portion of the present invention; Figure 5 This is a schematic diagram of the pressing mechanism of the present invention; Figure 6 This is a schematic diagram of the clamping mechanism portion of the present invention; Figure 7 This is an exploded view of the clamping mechanism of the present invention; Figure 8 This is a schematic diagram of the connection between the drive frame and the eccentric gear set of the present invention; Figure 9 This is a schematic diagram of the connection between the motor and the reducer of the present invention; Figure 10 This is an exploded view of the eccentric gear set of the present invention. Figure label: 1. Shell; 2. Mouthpiece; 21. Spray channel; 22. Air inlet; 3. Medicine bottle fixing mechanism; 31. Drive frame; 311. Fixing ring; 312. Connecting rod; 313. First anti-detachment rib; 314. Connecting frame; 32. Pressing mechanism; 321. Pressing cover; 322. Second anti-detachment rib; 323. Pressing component; 33. Clamping mechanism; 331. Clamping seat; 332. Clamp; 333. Third elastic element; 334. Clamping cavity; 335. Clearance hole; 336. Second extrusion slope; 34. First elastic element; 35. Second elastic element; 36. Ring; 37. Compression bar; 371. First extrusion ramp 4. Electric drive mechanism; 41. Housing; 42. First output shaft; 43. First eccentric gear; 44. Second output shaft; 45. Second eccentric gear; 46. Motor; 47. Reducer; 5. Inhalation detection module. Detailed Implementation To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. In the description of the present invention, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "inner," "outer," "vertical," "circumferential," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention. In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances. In the description of this invention, "first feature" and "second feature" may include one or more of the indicated features. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with "first" and "second" may explicitly or implicitly include one or more of the indicated features. like Figures 1-10 The invention shown is an intelligent electric drug delivery device for pressurized metered aerosols. The device includes a housing 1, a mouthpiece 2, a bottle fixing mechanism 3, an electric drive mechanism 4, an inhalation detection module 5, and a control module. The housing 1 is a structural component that forms the outer main body of the device, used to house and support the various internal functional parts. Its shape and material can be determined according to industrial design and functional requirements. For example... Figure 1 and Figure 2As shown, the shell 1 is provided with a mouthpiece 2 that the patient needs to put into his mouth when taking the medicine. The mouthpiece 2 is provided with a spray channel 21 inside, and an air inlet 22 that communicates with the spray channel 21. When the patient inhales, the medicine spray released from the medicine bottle can enter the patient's mouth through the spray channel 21. like Figure 1 and Figure 3 As shown, the bottle fixing mechanism 3 is used to install and fix the pressurized metered aerosol bottle and can drive its movement. The bottle fixing mechanism 3 is movably mounted on the housing 1. Specifically, it can move linearly relative to the housing 1. The installation position of the bottle fixing mechanism 3 is designed on one side of the air inlet 22 of the mouthpiece 2, so that the bottle nozzle can be directly aligned with and inserted into the air inlet 22. The bottle fixing mechanism 3 fixes the bottle in a reusable manner, that is, the bottle can be securely installed for spraying, and can also be safely removed with a simple operation when spraying is finished or when replacement is needed. When the medicine bottle fixing mechanism 3 is driven to move relative to the housing 1, it will synchronously move the entire medicine bottle that is fixed by it. As a result, the nozzle of the medicine bottle is squeezed, thereby triggering the valve inside the nozzle and releasing the medicine spray into the spray channel 21. like Figure 1 As shown, the electric drive mechanism 4 is mounted on the housing 1 and is connected to the medicine bottle fixing mechanism 3. Its function is to generate mechanical power after receiving the start command, and drive the medicine bottle fixing mechanism 3 to perform the aforementioned moving action. like Figure 2 As shown, the inhalation detection module 5 is a sensor component used to sense the patient's inhalation action through the mouthpiece 2. The module is set inside the mouthpiece 2 or in the airflow path connected to it. When the patient holds the mouthpiece 2 in their mouth and inhales, the change in airflow will be detected by the module and converted into a detection signal that can be recognized by subsequent circuits. The control module is the core of the device. It is electrically connected to the inhalation detection module 5 and the electric drive mechanism 4. The control module receives the detection signal from the inhalation detection module 5. When the detection signal reaches the preset condition, the control module will automatically control the electric drive mechanism 4 to work, thereby accurately driving the medicine bottle fixing mechanism 3 to move and complete one release of medicine spray. Therefore, this solution essentially constructs a closed-loop automated drug delivery system. The inhalation detection module 5 senses the patient's respiratory status in real time, and the control module automatically triggers the drug delivery action, fundamentally eliminating the hand-mouth coordination requirement of traditional methods where the patient manually presses the medicine bottle while inhaling. This ensures a high degree of synchronization between drug release and the patient's inhalation process, helping the drug to be deposited more effectively in the lungs, improving drug utilization, enhancing treatment efficacy, and improving medication adherence. In some implementations, such as Figure 3 and Figure 5 As shown, the medicine bottle fixing mechanism 3 is equipped with a manually pressable button 323. The button 323 is configured to respond to the manual pressing force applied by the user, independently of the electric drive mechanism 4, directly drive the medicine bottle fixing mechanism 3 to perform the movement action of releasing the medicine spray. This allows the device to achieve two core operating modes in actual use: an electric automatic mode and a manual mode. The electric automatic mode makes the device more intelligent and efficient, while compatibility with the traditional manual mode provides higher safety redundancy, thus providing dual protection for patient treatment and greatly improving the reliability and practicality of the device in actual use. Specifically, in the electric automatic mode: the patient switches the device to automatic mode and holds the mouthpiece 2 in their mouth. When the patient begins a proper inhalation, the inhalation detection module 5 detects a characteristic airflow signal. The control module determines that the signal has reached a preset threshold and then drives the electric drive mechanism 4. The electric drive mechanism 4 drives the bottle fixing mechanism 3 to move the entire bottle a certain distance, causing the bottle nozzle to be pressurized and spray the medication. Under the continuous inhalation airflow from the patient, the medication enters the respiratory tract through the spray channel 21 of the mouthpiece 2. This process is completely automatic and requires no manual intervention from the patient. In manual mode, users can also choose to operate the device manually, without relying on the automatic system. This involves the user applying pressure to the specially designed pressing element 323 on the bottle-holding mechanism 3. This force is directly transmitted through the purely mechanical structure inside the bottle-holding mechanism 3, driving the bottle to move and compress the nozzle to spray the medication. This operation path is independent of the electric drive mechanism 4 and its control system, ensuring basic medication administration even in the event of a power outage or electronic malfunction. In some implementations, such as Figure 3 As shown, the medicine bottle fixing mechanism 3 includes a drive frame 31, a pressing mechanism 32, and a clamping mechanism 33. The drive frame 31 is a frame-like structure that can move within the housing 1, and the movement of the drive frame 31 is directly driven by the electric drive mechanism 4. The clamping mechanism 33 is also a movable component within the housing 1, and its core function is to directly and detachably clamp and fix the medicine bottle. A first elastic element 34 is connected between the clamping mechanism 33 and the housing 1. This elastic element is used to provide a restoring force: when the clamping mechanism 33 is moved by being pushed, the elastic potential energy stored in the first elastic element 34 will be released after the pushing force is removed, driving the clamping mechanism 33 back to its initial position. The pressing mechanism 32 is an intermediate component connecting the drive frame 31 and the clamping mechanism 33, serving to transmit and convert force and motion. The pressing mechanism 32 integrates the aforementioned pressing element 323, and operates in two modes: in automatic mode, it is pushed by the moving drive frame 31; in manual mode, it is directly pressed by the user via the pressing element 323. Regardless of the driving method, the pressing mechanism 32 transmits the received motion to the clamping mechanism 33, thereby causing the clamping mechanism 33 to move. The pressing mechanism 32 itself is also connected to the housing 1 by a second elastic element 35. The function of the second elastic element 35 is similar to that of the first elastic element 34, which is to provide an elastic force to reset the pressing mechanism 32 after it moves. Therefore, by decomposing the medicine bottle fixing function into three parts—driving, transmitting, and clamping—and supplementing it with a reliable elastic reset mechanism, the automatic driving and manual driving can be efficiently converged into the final clamping mechanism 33 through the shared component of the pressing mechanism 32. The structure is reasonably designed and the operation is reliable. In some implementations, such as Figure 6 and Figure 7 As shown, the clamping mechanism 33 includes a clamping seat 331, a clamp 332, and a third elastic member 333. The clamping seat 331 defines a clamping cavity 334 for accommodating a medicine bottle. The clamp 332 is movably disposed within the clamping cavity 334. One side of the clamp 332 has a protrusion to facilitate clamping the neck of the medicine bottle. A third elastic member 333 is disposed between the clamp 332 and the clamping seat 331. This third elastic member 333 is designed to drive the clamp 332 outward in its natural state, thereby releasing the clamp 332 and allowing the medicine bottle to be freely inserted or removed. The pressing mechanism 32 and the drive frame 31 are detachably connected. When the pressing mechanism 32 is installed on the drive frame 31, during or after installation, the pressing mechanism 32 drives the clamp 332 to move inward against the force of the third elastic element 333, thereby locking the neck of the medicine bottle. At this time, the third elastic element 333 is compressed. When it is necessary to remove the medicine bottle, the pressing mechanism 32 is detached from the drive frame 31. At this time, the constraint force applied to the clamp 332 disappears, and the compressed or stretched third elastic element 333 releases its stored potential energy, driving the clamp 332 to move outward to reset, thereby releasing the medicine bottle. Thus, the convenience of medicine bottle loading and unloading and the stability of fixing are achieved. In some implementations, such as Figure 4 and Figure 5 As shown, the pressing mechanism 32 includes a pressing cover 321, which is detachably connected to the drive frame 31, and a ring 36 is provided between the pressing cover 321 and the clamping seat 331. like Figure 5 and Figure 7As shown, the ring 36 is a sleeve-shaped component used to fit onto the medicine bottle. The ring 36 is configured to be movable relative to the housing 1 along its own axial direction. The aforementioned second elastic member 35 is connected between the ring 36 and the housing 1. A pressure rod 37 extends from one end of the ring 36 toward the clamping seat 331, and the end of the pressure rod 37 is machined with a first extrusion bevel 371. The clamping seat 331 is provided with a clearance hole 335 communicating with the clamping cavity 334, into which the pressure rod 37 can extend. The clamp 332 is provided with a second extrusion bevel 336. When the press cap 321 is installed onto the drive frame 31, the installation action causes the press cap 321 to move a short distance towards the clamping seat 331, along with the ring 36. As the ring 36 moves, the first pressing ramp 371 of its pressure rod 37 comes into contact with and slides relative to the second pressing ramp 336 on the clamp 332. Due to the effect of the ramp structure, the axial movement of the ring 36 is converted into an inward component force acting on the clamp 332. This force pushes the clamp 332 inward against the resistance of the third elastic element 333, thereby ultimately locking the medicine bottle. Therefore, by using a beveled joint, the installation / pressing action is efficiently and reliably converted into a clamping action, resulting in a compact structure and sensitive operation. This design allows the fixed state of the medicine bottle to be directly linked to the installed state of the press cap 321, making operation intuitive and reliable. In some implementations, such as Figure 4 and Figure 5 As shown, the drive frame 31 includes a retaining ring 311 and a connecting rod 312. The retaining ring 311 is a ring-shaped component with a central hole for the medicine bottle to pass through. The connecting rod 312 is connected to the retaining ring 311 and is connected to the electric drive mechanism 4. The pressing cap 321 and the retaining ring 311 are detachably connected by a rotatable mechanism. Specifically, the inner edge of the retaining ring 311 is provided with a first anti-detachment rib 313, and the outer edge of the pressing cover 321 is provided with a corresponding second anti-detachment rib 322. When the user aligns the pressing cover 321 with the retaining ring 311 and rotates it clockwise, the second anti-detachment rib 322 will slide along the contour of the first anti-detachment rib 313 and eventually stop against the first anti-detachment rib 313 to achieve a locking connection; rotating it in the opposite direction will separate the two. In some embodiments, to facilitate screwing in installation, one end of the first anti-detachment rib 313 is provided with a guide slope, which facilitates the screwing of the second anti-detachment rib 322 into the first anti-detachment rib 313. The other end of the first anti-detachment rib 313 is provided with a stop member, which can remind the press cover 321 to rotate into place. In some implementations, such as Figure 3 and Figure 5As shown, the press cap 321 is manufactured as a cylindrical structure with one end open and the other closed, and a second anti-detachment rib 322 is provided on the outer edge of the open end. When the press cap 321 is rotated and installed onto the retaining ring 311, its cylindrical part covers the outside of the medicine bottle, providing a certain degree of protection and guidance. Its closed end extends outward beyond the retaining ring 311, forming a protruding part that is easy to apply force to. This protruding closed end naturally constitutes the press element 323 for the user to press manually. Furthermore, the design of the cylindrical press cap 321 can also adapt to medicine bottles of different heights, thereby enhancing the versatility and flexibility of this device. In some embodiments, the ring 36 and the clamping seat 331 are respectively provided with rod holes. The connecting rod 312 of the drive frame 31 passes through the rod holes of the ring 36 and the clamping seat 331 in sequence, and is then connected to the electric drive mechanism 4. This makes the structure more compact, and the connecting rod 312 can also guide the movement of the ring 36 and the clamping seat 331. In some implementations, such as Figure 8 As shown, the drive frame 31 also includes a connecting frame 314, which is fixedly connected to the connecting rod 312, and the connecting frame 314 has a shaft hole. like Figure 9 and Figure 10 As shown, the electric drive mechanism 4 specifically includes a motor 46, a reducer 47, and an eccentric gear set. The motor 46 is connected to the reducer 47, which reduces the speed of the output shaft of the motor 46 while increasing the output torque. The eccentric gear set is a mechanism that converts rotary motion into reciprocating linear motion. The eccentric gear set includes a housing 41, which houses a pair of meshing first eccentric gears 43 and second eccentric gears 45. The first eccentric gear 43 is connected to a first output shaft 42, which is connected to the output end of the reducer 47. The second eccentric gear 45 is connected to a second output shaft 44, which is rotatably inserted into the shaft hole of the connecting bracket 314. After the motor 46 starts, the power is transmitted to the first output shaft 42 via the reducer 47, which drives the first eccentric gear 43 to rotate. The first eccentric gear 43 drives the second eccentric gear 45 to rotate. Due to the eccentric design of the gears, the second output shaft 44 rotates while driving the connecting frame 314 connected to it, which in turn drives the entire drive frame 31 to perform regular, short-stroke reciprocating linear motion. This eccentric gear mechanism efficiently converts the continuous rotation of the motor 46 into the precise linear stroke required by the drive frame 31, ensuring consistency in the force and stroke of each press on the medicine bottle, which is crucial for ensuring the accuracy of the dosage of the metered aerosol spray each time. In some embodiments, the inhalation detection module 5 is a pressure sensor, wherein a baffle is provided inside the airflow channel to reduce the cross-sectional area of ​​the airflow channel, and a pressure sensor is installed at the baffle. When the patient inhales by holding the mouthpiece 2 in their mouth, the airflow velocity increases as it passes through the baffle. When the pressure sensor detects that the pressure change reaches a certain threshold, automatic medication can be sprayed. In some embodiments, the device also includes a limit detection module, a medicine bottle detection module, a press cap 321 detection module, and a manual press detection module. These detection blocks mainly use limit switches in conjunction with mechanical structures to sense position or action. Specifically, the limit detection module is used to precisely control the stop position of the electric drive mechanism 4 during automatic spraying. The limit detection module consists of a cam fixedly connected to the output shaft of the electric drive mechanism 4 and a corresponding limit switch. When the output shaft rotates, causing the cam to rotate as well, the flange on the cam periodically presses down on the head block of the limit switch. When the control module detects the signal of the limit switch being pressed down, it determines that a complete automatic spraying cycle has ended and immediately controls the motor 46 to stop, thereby ensuring that the amplitude of each automatic spraying action is consistent and preventing overshoot. The medicine bottle detection module is used to confirm whether the medicine bottle is correctly installed. The medicine bottle detection module is a limit switch, positioned so that when the medicine bottle is fully inserted and installed in the predetermined position, the bottle body or a specific part of the limit switch will press down on the head stop. Upon receiving this signal, the control module determines that the medicine bottle is correctly installed, providing a prerequisite for allowing spraying. The press cover 321 detection module is used to confirm whether the press cover 321 has been correctly screwed in and locked. The press cover 321 detection module is a limit switch, and its installation position is such that when the press cover 321 is rotated and installed to the working position, the press cover 321 will press down the head stop of the limit switch. Based on this, the control module determines that the press cover 321 is properly installed and the system can enter the ready state. The manual press detection module is used to identify whether the user has performed a manual spraying operation. The manual press detection module is a limit switch, and its setting position is associated with the clamping mechanism 33 or its linked components. When the user manually presses down the pressing cap 321 to spray, the linked component moves accordingly and presses down the head stop of this limit switch. The control module detects this signal and records a manual spraying event. This signal can also be used to trigger related status updates or recordings. In some implementations, the control module includes: The power module is used to provide power to all electrical components of the device. The display module, such as a display screen, can be used to display device status information, such as battery level, remaining uses of medicine bottles, network connection status, and current working mode. The voice module, which may be a buzzer or a miniature speaker and its driving circuit, is used to provide voice prompts, such as operation guidance, medication reminders, and error alarms. The attitude sensor module is a sensor used to detect the device's angle, orientation, or motion state in space, such as an accelerometer and a gyroscope. Its function is to detect changes in the drug delivery device's posture during use, such as whether the device is being held correctly or whether the patient's head angle is appropriate during inhalation. The main controller is connected to the power module, display module, voice module, attitude sensor module, inhalation detection module 5, and electric drive mechanism 4 via circuitry. Its function is to receive and process signals from the inhalation detection module 5 and / or attitude sensor module, and, according to preset program logic, issue corresponding control commands to the display module, voice module, and electric drive mechanism 4 to drive them to perform specific actions. This enables a complete, multifunctional intelligent control system. The system not only realizes the automatic drug delivery function triggered by inhalation, but also expands advanced functions such as medication guidance, status monitoring, and user reminders by integrating posture perception and rich human-computer interaction modules, making it convenient for users. In summary, this device has the following characteristics: 1. Intelligent Synchronous Trigger: Through highly sensitive inhalation detection and rapid response control, the drug release and the patient's inhalation process are automatically and accurately synchronized, fundamentally solving the hand-mouth coordination problem of traditional pMDI and improving the efficiency of drug deposition in the lungs. 2. Dual-mode drive protection: It integrates two independent systems, a fully automatic electric drive and a purely mechanical manual drive, providing a redundant safety mechanism to ensure reliable drug delivery under any circumstances. 3. Adaptive and stable clamping: Adopting an innovative inclined plane driven radial locking mechanism, it can achieve quick assembly and disassembly. Combined with the cylindrical press cap 321, it can stably clamp standard pMDI medicine bottles of various sizes, making it highly versatile and easy to use. 4. Compact and reliable structure: It adopts an eccentric gear and other efficient transmission and reset mechanism to accurately convert rotational power into linear pressing action. The structure is compact and the operation is stable, ensuring the consistency and accuracy of drug administration. 5. Intelligent medication guidance: Built-in posture sensor and interaction module can monitor medication posture and guide users to operate correctly through visual and voice feedback, improving treatment compliance and effectiveness. Although some embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and variations of these embodiments without departing from the principles and spirit of the present invention are within the scope of protection of the claims of the present invention.

Claims

1. A smart electric drug delivery device for pressurized metered-dose aerosols, comprising: case; The mouthpiece is disposed on the housing, and the mouthpiece has a spray channel inside for the patient to inhale, and the mouthpiece has an air inlet communicating with the spray channel; A bottle fixing mechanism is movably mounted on the housing and located on one side of the air inlet. The bottle fixing mechanism is used to fix the pressurized metered aerosol bottle in a removable manner and to align the nozzle of the bottle with and extend it into the air inlet. The bottle fixing mechanism is configured to move relative to the housing to drive the fixed bottle to squeeze the nozzle, thereby releasing the medicine spray into the spray channel. An electric drive mechanism is provided on the housing and is connected to the medicine bottle fixing mechanism to drive the medicine bottle fixing mechanism to move under control. An inhalation detection module is disposed inside the mouthpiece. The inhalation detection module is used to detect the patient's inhalation action through the mouthpiece and generate a corresponding detection signal. The control module is electrically connected to the inhalation detection module and the electric drive mechanism respectively. The control module is configured to automatically control the electric drive mechanism when the detection signal reaches a preset condition, so as to drive the medicine bottle fixing mechanism to perform a movement action to release medicine spray.

2. The intelligent electric drug delivery device for pressurized metered aerosols according to claim 1, characterized in that, The medicine bottle fixing mechanism is equipped with a pressing element that can be manually pressed; The pressing element is configured to, in response to manual pressing pressure applied by the user, directly drive the medicine bottle fixing mechanism to perform a movement action that releases the medicine spray, independent of the electric drive mechanism.

3. The intelligent electric drug delivery device for pressurized metered aerosols according to claim 2, characterized in that, The medicine bottle fixing mechanism includes a drive frame, a pressing mechanism, and a clamping mechanism; The clamping mechanism is movably disposed within the housing for detachably clamping and fixing the medicine bottle. A first elastic element is provided between the clamping mechanism and the housing, which provides an elastic force to reset the clamping mechanism after it moves. The drive frame is movably disposed within the housing, and the electric drive mechanism is connected to the drive frame to drive the drive frame to move; The pressing mechanism is connected between the drive frame and the clamping mechanism. The pressing mechanism is provided with the pressing element. The pressing mechanism is driven by the drive frame or manually driven by the pressing element, thereby driving the clamping mechanism to move. A second elastic element is provided between the pressing mechanism and the housing, the second elastic element being used to provide an elastic force to reset the pressing mechanism after it moves.

4. The intelligent electric drug delivery device for pressurized metered-dose aerosols according to claim 3, characterized in that, The clamping mechanism includes a clamping seat, a clamp, and a third elastic element; The clamping seat defines a clamping cavity for accommodating the medicine bottle, and the clamp is movably disposed in the clamping cavity. The clamp is configured to hold the bottleneck of the medicine bottle. A third elastic member is provided between the clamp and the clamping seat. The third elastic member is used to drive the clamp to move outward to release the medicine bottle under normal conditions. The pressing mechanism is detachably connected to the drive frame; When the pressing mechanism is installed on the drive frame, the pressing mechanism is used to drive the clamp to move inward to lock the medicine bottle; When the pressing mechanism is removed, the third elastic element drives the clamp to reset outward to release the medicine bottle.

5. The intelligent electric drug delivery device for pressurized metered aerosols according to claim 4, characterized in that, The pressing mechanism includes a pressing cover, which is detachably connected to the drive frame, and a ring is provided between the pressing cover and the clamping seat; The ring is used to be fitted onto the medicine bottle. The ring is axially movable relative to the housing and a second elastic element is provided between the ring and the housing. A pressure rod is provided at one end of the ring facing the clamping seat, and a first extrusion slope is provided on the pressure rod. The clamping seat is provided with a clearance hole communicating with the clamping cavity, and the clamp is provided with a second pressing slope; the pressure rod extends into the clearance hole, and the first pressing slope cooperates with the second pressing slope; When the press cap is installed on the drive frame, the press cap drives the ring to move toward the clamping seat, and the first pressing slope presses the second pressing slope to drive the clamp to move inward and clamp the medicine bottle.

6. The intelligent electric drug delivery device for pressurized metered aerosols according to claim 5, characterized in that, The drive frame includes a fixed ring and a connecting rod. The fixed ring is used for the medicine bottle to pass through. The connecting rod is provided on the fixed ring and is connected to the electric drive mechanism. The pressing cap is rotatably and detachably connected to the fixed ring. The inner edge of the fixing ring is provided with a first anti-detachment rib, and the outer edge of the pressing cover is provided with a second anti-detachment rib. When the press cover is rotated in the forward direction, the second anti-detachment rib can be screwed in and engaged below the first anti-detachment rib. Rotating the press cover in the reverse direction can separate the second anti-detachment rib from the first anti-detachment rib.

7. The intelligent electric drug delivery device for pressurized metered-dose aerosols according to claim 6, characterized in that, The press cover is a cylindrical structure with one end open and the other end closed, and the outer edge of the open end of the press cover is provided with the second anti-detachment rib. When the press cap is installed on the fixing ring, the press cap covers the outside of the medicine bottle, and the closed end of the press cap extends outward from the fixing ring to form the press element.

8. The intelligent electric drug delivery device for pressurized metered-dose aerosols according to claim 6, characterized in that, The drive frame also includes a connecting frame connected to the connecting rod, and the connecting frame is provided with a shaft hole; The electric drive mechanism includes a motor, a reducer, and an eccentric gear set. The eccentric gear set includes a housing, a first output shaft, a first eccentric gear, a second output shaft, and a second eccentric gear. The housing contains a first eccentric gear and a second eccentric gear that mesh with each other. The first eccentric gear is connected to the first output shaft, and the second eccentric gear is connected to the second output shaft. The motor is connected to the first output shaft through the reducer, and the second output shaft is rotatably inserted into the shaft hole.

9. The intelligent electric drug delivery device for pressurized metered-dose aerosols according to claim 1, characterized in that, The intake detection module is a pressure sensor, and a baffle is provided inside the airflow channel to reduce the cross-sectional area of ​​the airflow channel. The pressure sensor is located at the baffle.

10. The intelligent electric drug delivery device for pressurized metered-dose aerosols according to claim 1, characterized in that, The control module includes: A power module is provided to supply power to the various units inside the electric drive mechanism, the intake detection module, and the control module. The display module is used to display device status information; A voice module, which provides voice prompts; An attitude sensor module is provided for detecting attitude changes of the drug delivery device during use. The main controller is electrically connected to the power module, display module, voice module, attitude sensor module, inhalation detection module, and electric drive mechanism. The main controller is used to control the operation of the display module, voice module, and electric drive mechanism based on the signals from the inhalation detection module and / or attitude sensor module.

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