Scalp micro-ecological hair follicle conditioning liquid and preparation method thereof
By scientifically compounding the scalp microecological hair follicle conditioning solution, the problems of single function and unreasonable ingredients in existing products are solved, and multiple effects are achieved synergistically. It provides a gentle and stable scalp conditioning solution suitable for long-term maintenance of various scalp problems.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-01-22
- Publication Date
- 2026-03-17
AI Technical Summary
Existing hair follicle conditioning products have limited functions and cannot simultaneously address issues such as scalp microecological imbalance, barrier repair, and sensitivity soothing. Furthermore, they suffer from chemical irritation, unreasonable ingredient ratios leading to activity conflicts and poor stability, making them unable to maintain scalp health in the long term.
The product employs a scientific blend of degreasing compositions, hypoallergenic compositions, suitable mixed compositions, and suitable anti-hair loss compositions, combined with the adjustment of disodium EDTA, glycerin, and triethanolamine. By optimizing the mixing method and fine filtration steps, the synergistic effect of active ingredients and product stability are ensured.
It achieves a synergistic effect of multiple functions, comprehensively regulates the scalp microecology, is gentle and hypoallergenic, is suitable for a wide range of people, maintains the health of the scalp and hair follicles in the long term, and the preparation process is easy to scale up.
Abstract
Description
Technical Field
[0001] This invention relates to the field of hair follicle conditioning technology, specifically to a scalp microecological hair follicle conditioning solution and its preparation method. Background Technology
[0002] With increasing life stress, irregular schedules, environmental pollution, and excessive cleaning, problems such as excessive scalp oil production, Malassezia growth, damaged scalp barrier, hair loss, and sensitivity / redness are becoming increasingly common, severely disrupting the scalp's microecological balance and affecting scalp health and hair condition. Currently available hair follicle conditioning products have many shortcomings: Some products have limited functionality, focusing only on oil control or hair loss prevention, failing to simultaneously address multiple issues such as scalp microecological imbalance, barrier repair, and sensitivity soothing. Other products contain irritating chemicals, easily triggering adverse reactions like scalp allergies, dryness, and tightness. Still others suffer from unreasonable ingredient ratios, leading to conflicting active ingredients and poor stability, resulting in short-lived conditioning effects and insufficient moisturizing duration, making it difficult to maintain long-term scalp health. Furthermore, existing products often neglect the synergistic regulation of the scalp microecology, failing to achieve the synergistic effects of oil control, antibacterial action, hair loss prevention, moisturizing, and repair, thus failing to improve the scalp environment at its root. Therefore, developing a multifunctional, synergistic, gentle, hypoallergenic, and highly stable hair follicle conditioning solution that comprehensively regulates the scalp microecology has become a pressing technological need for the industry. Summary of the Invention
[0003] To address the shortcomings of existing technologies, this invention provides a scalp microecological hair follicle conditioning solution and its preparation method, thus solving the problems mentioned above in the background technology.
[0004] To achieve the above objectives, the present invention provides the following technical solution: a scalp microecological hair follicle conditioning solution, comprising 6.5% oil-removing composition, 2.5% hypoallergenic composition, 6.5% suitable mixed composition, 6.5% suitable anti-hair loss composition, 0.1% disodium EDTA, 3% glycerin, 0.2% triethanolamine and 74.7% deionized water.
[0005] Preferably, the degreasing composition contains 2% nicotinamide, 1% prebiotic, 0.3% ceramide triglyceride, 1% panthenol, and 95.7% deionized water.
[0006] Preferably, the preparation steps of the degreasing composition are as follows: A1. Mix nicotinamide and prebiotics, grind them into powder and pass them through an 80-mesh sieve. Add 47.85% deionized water and stir for 10 minutes at 28°C and 60 r / min until completely dissolved. A2. Adjust the pH of the system to 5.8 with citric acid, add ceramide tris, stir for 5 minutes, then add panthenol and continue stirring for 15 minutes. A3. Add the remaining 47.85% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; A4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the degreasing composition.
[0007] Preferably, the hypoallergenic composition comprises 3% Platycladus orientalis leaf extract, 2% Lactobacillus fermentation product, 0.2% ceramide trioxide, 0.2% sodium hyaluronate, and 94.6% deionized water.
[0008] Preferably, the method for preparing the hypoallergenic composition is as follows: B1. Mix the arborvitae leaf extract with the lactobacillus fermentation product, grind it into powder and pass it through an 80-mesh sieve. Add 47.3% deionized water and stir for 10 minutes at 25°C and 60 r / min until completely dissolved. B2. Adjust the pH of the system to 6.2 with citric acid, add ceramide tris, stir for 5 minutes, then add sodium hyaluronate and continue stirring for 15 minutes. B3. Add the remaining 47.3% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; B4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain a low-sensitivity composition.
[0009] Preferably, the adaptable mixed composition contains 2% meadowsweet extract, 0.3% clomiphene citrate, 2% panthenol, 0.1% sodium hyaluronate, and 95.6% deionized water.
[0010] Preferably, the preparation method of the adaptable mixed composition is as follows: C1. Mix meadowsweet extract with clomiphene citrate, grind into powder and pass through an 80-mesh sieve. Add 47.8% deionized water and stir for 10 minutes at 30°C and 60 r / min until completely dissolved. C2. Adjust the pH of the system to 6.0 with citric acid, add panthenol, stir for 5 minutes, then add sodium hyaluronate and continue stirring for 15 minutes. C3. Add the remaining 47.8% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; C4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the suitable mixed composition.
[0011] Preferably, the adapted anti-hair loss composition comprises 2% caffeine, 1.5% prebiotics, 0.3% ceramide triglycerides, 0.02% biotin, and 96.18% deionized water.
[0012] Preferably, the preparation steps of the anti-hair loss composition are as follows: D1. Mix caffeine and prebiotics, grind them into powder and pass through an 80-mesh sieve. Add 48.09% deionized water and stir for 10 minutes at 27°C and 60 r / min until completely dissolved. D2. Adjust the pH of the system to 5.6 with citric acid, add ceramide tris, stir for 5 minutes, then add biotin and continue stirring for 15 minutes. D3. Add the remaining 48.09% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; D4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the suitable anti-hair loss composition.
[0013] A method for preparing a scalp microecological hair follicle conditioning solution includes the following steps: S1. Pretreatment preparation: Place 6.5% of the oil composition, 2.5% of the low-sensitivity composition, 6.5% of the suitable mixed composition, and 6.5% of the suitable anti-hair loss composition in a constant temperature environment of 25℃ for 30 minutes to equilibrate the temperature. S2. Preparation of basic solvent: Take 74.7% of the formula amount of deionized water, add 0.1% of disodium EDTA, and stir for 5 minutes at 30℃ and 60r / min until the disodium EDTA is completely dissolved; then add 3% of glycerol and continue stirring for 10 minutes to form a homogeneous basic solvent system. S3. Stepwise mixing of functional ingredients: Maintain a stirring speed of 60 r / min, first slowly add 6.5% of the degreasing composition, and stir for 15 min until completely dispersed; then add 2.5% of the hypoallergenic composition, and stir for 10 min; then add 6.5% of the adaptable mixed composition and 6.5% of the adaptable anti-hair loss composition in sequence, stirring for 10 min after each addition to ensure that the functional ingredients gradually blend and avoid activity conflicts caused by excessively high local concentrations; S4. pH balance adjustment: The pH of the system is adjusted by synergistic adjustment of citric acid and triethanolamine: First, add 10% citric acid solution to initially adjust the pH to 5.5-5.6, then add 5% triethanolamine solution to fine-tune the pH to 5.8-6.0. During the adjustment process, keep the stirring speed at 60 r / min. After the adjustment is completed, continue stirring for 15 min. S5. Enhance dispersion and stability: Increase the stirring speed to 85 r / min and continue stirring for 25 min to fully homogenize the system; then stop stirring and let it stand in a constant temperature environment of 25℃ for 40 min to release residual air bubbles in the system. S6. Fine Filtration and Finished Product: After the system has been allowed to stand, it is finely filtered through a 0.22μm polyethersulfone filter membrane to remove any trace impurities or incompletely dissolved particles. The filtered liquid is collected and is the scalp microecological hair follicle conditioning solution.
[0014] This invention provides a scalp microecological hair follicle conditioning solution and its preparation method, which has the following beneficial effects: (1) This scalp microecological hair follicle conditioning solution achieves synergistic unity of multiple effects through the scientific compounding of multiple functional compositions. It can comprehensively regulate the balance of scalp microecology and specifically improve a variety of scalp-related problems. The product formula is mild and low in irritation, and is suitable for the physiological environment of the scalp. It avoids the defects of traditional products such as single function and easy to cause discomfort. It is suitable for a wide range of people and can maintain the health of the scalp and hair follicles for a long time.
[0015] (2) The preparation method of this scalp microecological hair follicle conditioning solution is scientifically and rationally designed. By optimizing the mixing method, adjusting the system compatibility, strengthening dispersion stability and fine filtration purification, the activity and synergistic effect of each active ingredient are effectively guaranteed, and component conflicts or activity loss are avoided. The preparation process is standardized, requires no complex equipment, has low energy consumption, is easy to scale up production, and improves the overall stability and user experience of the product, solving many shortcomings in the existing related product preparation processes. Detailed Implementation
[0016] Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0017] The raw materials used in the examples and comparative examples are all commercially available.
[0018] Preparation example of degreasing composition Preparation Example 1-1 Core ingredients (by weight): 2% nicotinamide, 1% prebiotics (fructooligosaccharides), 0.3% ceramide triglycerides, 1% panthenol, 95.7% deionized water; Preparation steps: A1. Mix nicotinamide and prebiotics, grind them into powder and pass them through an 80-mesh sieve. Add 47.85% deionized water and stir for 10 minutes at 28°C and 60 r / min until completely dissolved. A2. Adjust the pH of the system to 5.8 with citric acid, add ceramide tris, stir for 5 minutes, then add panthenol and continue stirring for 15 minutes. A3. Add the remaining 47.85% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; A4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the degreasing composition.
[0019] Preparation Examples 1-2 The difference from Preparation Example 1-1 is that panthenol is not added; Preparation Examples 1-3 The difference from Preparation Example 1-1 is that ceramide tris is not added; Preparation Examples 1-4 The difference from Preparation Example 1-1 is that the core raw materials (by mass percentage) are: nicotinamide 2%, prebiotics (fructooligosaccharides) 2%, ceramide triglycerides 0.3%, panthenol 1%, and deionized water 94.7%; Preparation Examples 1-5 The difference from Preparation Example 1-1 is that the core raw materials (by mass percentage) are: nicotinamide 1%, prebiotics (fructooligosaccharides) 1%, ceramide triglycerides 0.3%, panthenol 1%, and deionized water 96.7%; Preparation Examples 1-6 The difference from Preparation Example 1-1 is that the core raw materials (by mass percentage) are: nicotinamide 2%, prebiotics (fructooligosaccharides) 1%, ceramide triglycerides 1%, panthenol 1%, and deionized water 95%; Preparation example of hypoallergenic composition Preparation Example 2-1 Core ingredients (by weight): 3% Platycladus orientalis leaf extract, 2% Lactobacillus fermentation product, 0.2% Ceramide III, 0.2% Sodium hyaluronate, 94.6% Deionized water; Preparation steps: B1. Mix the arborvitae leaf extract with the lactobacillus fermentation product, grind it into powder and pass it through an 80-mesh sieve. Add 47.3% deionized water and stir for 10 minutes at 25°C and 60 r / min until completely dissolved. B2. Adjust the pH of the system to 6.2 with citric acid, add ceramide tris, stir for 5 minutes, then add sodium hyaluronate and continue stirring for 15 minutes. B3. Add the remaining 47.3% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; B4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain a low-sensitivity composition.
[0020] Preparation Example 2-2 The difference from Preparation Example 2-1 is that the core raw materials (by mass percentage) are: 2% Platycladus orientalis leaf extract, 2% Lactobacillus fermentation product, 0.2% ceramide trioxide, 0.2% sodium hyaluronate, and 95.6% deionized water; Preparation Examples 2-3 The difference from Preparation Example 2-1 is that the core raw materials (by mass percentage) are: 3% Platycladus orientalis leaf extract, 3% Lactobacillus fermentation product, 0.2% ceramide trioxide, 0.2% sodium hyaluronate, and 93.6% deionized water; Preparation Examples 2-4 The difference from Preparation Example 2-1 is that the core raw materials (by mass percentage) are: 1% Platycladus orientalis leaf extract, 1% Lactobacillus fermentation product, 0.2% ceramide trioxide, 0.2% sodium hyaluronate, and 96.6% deionized water; Preparation Examples 2-4 The difference from Preparation Example 2-1 is that the core raw materials (by mass percentage) are: 2% Platycladus orientalis leaf extract, 1% Lactobacillus fermentation product, 0.2% ceramide trioxide, 0.2% sodium hyaluronate, and 94.6% deionized water; Preparation example of adaptable mixed composition Preparation Example 3-1 Core ingredients (by weight): meadowsweet extract 2%, clomiphene citrate 0.3%, panthenol 2%, sodium hyaluronate 0.1%, deionized water 95.6%; Preparation steps: C1. Mix meadowsweet extract with clomiphene citrate, grind into powder and pass through an 80-mesh sieve. Add 47.8% deionized water and stir for 10 minutes at 30°C and 60 r / min until completely dissolved. C2. Adjust the pH of the system to 6.0 with citric acid, add panthenol, stir for 5 minutes, then add sodium hyaluronate and continue stirring for 15 minutes. C3. Add the remaining 47.8% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; C4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the suitable mixed composition; Preparation Example 3-2 The difference from Preparation Example 3-1 is that the core raw materials (by mass percentage) are: meadowsweet extract 1%, clomiphene 0.3%, panthenol 2%, sodium hyaluronate 0.1%, and deionized water 96.6%. Preparation Example 3-3 The difference from Preparation Example 3-1 is that the core raw materials (by mass percentage) are: meadowsweet extract 3%, clomiphene 0.3%, panthenol 2%, sodium hyaluronate 0.1%, and deionized water 94.6%; Preparation Examples 3-4 The difference from Preparation Example 3-1 is that the core raw materials (by mass percentage) are: meadowsweet extract 2%, clomiphene 0.4%, panthenol 2%, sodium hyaluronate 0.1%, and deionized water 95.7%. The difference from preparation examples 3-4 is that the core raw materials (by mass percentage) are: meadowsweet extract 2%, clomiphene 0.5%, panthenol 2%, sodium hyaluronate 0.1%, and deionized water 95.5%; Preparation example of adaptable anti-hair loss composition Preparation Example 4-1 Core ingredients (by weight): Caffeine 2%, Prebiotics (fructooligosaccharides) 1.5%, Ceramide Triglycerides 0.3%, Biotin 0.02%, Deionized Water 96.18%; Preparation steps: D1. Mix caffeine and prebiotics, grind them into powder and pass through an 80-mesh sieve. Add 48.09% deionized water and stir for 10 minutes at 27°C and 60 r / min until completely dissolved. D2. Adjust the pH of the system to 5.6 with citric acid, add ceramide tris, stir for 5 minutes, then add biotin and continue stirring for 15 minutes. D3. Add the remaining 48.09% of deionized water, increase the stirring speed to 80 r / min, and continue stirring for 20 min; D4. After standing for 30 minutes, filter through a 0.22μm filter membrane to obtain the suitable anti-hair loss composition.
[0021] Preparation Example 4-2 The difference from Preparation Example 4-1 is that the core ingredients (by mass percentage) are: caffeine 2%, prebiotics (fructooligosaccharides) 2%, ceramide triglycerides 0.3%, biotin 0.02%, and deionized water 95.68%; Preparation Example 4-3 The difference from Preparation Example 4-1 is that the core ingredients (by mass percentage) are: caffeine 3%, prebiotics (fructooligosaccharides) 1.5%, ceramide triglycerides 0.3%, biotin 0.02%, and deionized water 95.18%; Preparation Example 4-4 The difference from Preparation Example 4-1 is that the core ingredients (by mass percentage) are: caffeine 3%, prebiotics (fructooligosaccharides) 3%, ceramide triglycerides 0.3%, biotin 0.02%, and deionized water 93.68%; Example Example 1
[0022] A scalp microecological hair follicle conditioning solution comprises the following raw materials: 6.5% of an oil-removing composition (Preparation Example 1-1), 2.5% of a hypoallergenic composition (Preparation Example 2-1), 6.5% of an appropriate mixed composition (Preparation Example 3-1), 6.5% of an appropriate anti-hair loss composition (Preparation Example 4-1), 0.1% of disodium EDTA, 3% of glycerin, 0.2% of triethanolamine, and 74.7% of deionized water; This embodiment needs to be specifically supplemented with the following: disodium EDTA to avoid metal ions interfering with the activity of the components, glycerol to alleviate the osmotic pressure difference after the mixture of the various compositions, triethanolamine as a buffer regulator, and citric acid to synergistically balance the system. A method for preparing a scalp microecological hair follicle conditioning solution includes the following steps: S1. Pretreatment preparation: Place the compositions of Preparation Example 1-1, Preparation Example 2-1, Preparation Example 3-1 and Preparation Example 4-1 in a constant temperature environment of 25°C for 30 minutes to equilibrate the temperature, so as to ensure that the temperature of each composition is consistent and to avoid bubbles or stratification due to temperature difference during mixing. S2. Preparation of basic solvent: Take 74.7% of the formula amount of deionized water, add 0.1% of disodium EDTA, and stir for 5 minutes at 30℃ and 60r / min until the disodium EDTA is completely dissolved; then add 3% of glycerol and continue stirring for 10 minutes to form a homogeneous basic solvent system. S3. Stepwise mixing of functional ingredients: Maintain a stirring speed of 60 r / min, first slowly add 6.5% of the degreasing composition, and stir for 15 min until completely dispersed; then add 2.5% of the hypoallergenic composition, and stir for 10 min; then add 6.5% of the adaptable mixed composition and 6.5% of the adaptable anti-hair loss composition in sequence, stirring for 10 min after each addition to ensure that the functional ingredients gradually blend and avoid activity conflicts caused by excessively high local concentrations; S4. pH balance adjustment: The pH of the system is adjusted by synergistic adjustment of citric acid and triethanolamine: First, add 10% citric acid solution to initially adjust the pH to 5.5-5.6, then add 5% triethanolamine solution to fine-tune the pH to 5.8-6.0. During the adjustment process, keep the stirring speed at 60 r / min. After the adjustment is completed, continue stirring for 15 min. S5. Enhance dispersion and stability: Increase the stirring speed to 85 r / min and continue stirring for 25 min to fully homogenize the system; then stop stirring and let it stand in a constant temperature environment of 25℃ for 40 min to release residual air bubbles in the system. S6. Fine Filtration and Finished Product: After standing, the system is finely filtered through a 0.22μm polyethersulfone filter membrane to remove any trace impurities or incompletely dissolved particles. The filtered liquid is collected and is the scalp microecological hair follicle conditioning solution. Example 2
[0023] Example 2 is a scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-2; Example 3 is a scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-3; Example 4: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-3; Example 5 is a scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-4; Example 6 is a scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-5; Example 7: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 1-6; Example 8: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 2-1; Example 9: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 2-2; Example 10: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 2-3; Example 11: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 2-4; Example 12: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 3-1; Example 13: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 3-2; Example 14: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 3-3; Example 15: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it uses the comparative examples prepared in Preparation Examples 3-4; Example 16: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 4-1; Example 17: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Example 4-2; Example 18: A scalp microecological hair follicle conditioning solution, which differs from Example 1 in that it is prepared using Preparation Examples 4-3; Example 19: A scalp microecological hair follicle conditioning solution, differing from Example 1 in that it uses the comparative example prepared in Preparation Example 4-4. Comparative Example 1 The difference between Comparative Example 1 and Example 1 is that Preparation Example 1 is not included; Comparative Example 2 The difference between Comparative Example 2 and Example 1 is that Preparation Example 2 is not included. Comparative Example 3 The difference between Comparative Example 3 and Example 1 is that Preparation Example 3 is not included. Comparative Example 4 The difference between Comparative Example 4 and Example 1 is that Comparative Example 4 is not included. Specific data is shown in the table below. Category Sebum secretion inhibition rate (%) Malassezia inhibition rate (%) Repair rate of scalp barrier (%) 8h moisturizing persistence (%) Irritation (adverse reaction rate) Hair growth rate Example 1 65.3% 99.5 56.3% 82.2% 0% 5.21% Example 2 64.2% 99.5 46.9% 80.1% 0% 4.92% Example 3 57.7% 99.5 57.9% 83.1% 0% 3.91% Example 4 65.9% 99.5 54.6% 78.4% 0% 3.71% Example 5 68.4% 99.5 55.7% 78.7% 0% 3.61% Example 6 70.1% 99.5 58.9% 79.1% 0% 3.22% Example 7 54.6% 99.5 43.3% 79.5% 0% 3.28% Example 8 38.9% 99.5 43.6% 79.2% 0% 4.26% Example 9 45.8% 99.5 46.8% 83.7% 0% 4.37% Example 10 57.9% 99.5 42.4% 83.6% 0% 4.46% Example 11 60.4% 99.5 60.2% 82.7% 0% 4.79% Example 12 66.3% 99.5 60.3% 82.5% 0% 5.01% Example 13 65.7% 99.5 66.7% 86.7% 0% 5.22% Example 14 65.8% 99.5 49.3% 85.9% 0% 5.16% Example 15 65.3% 99.5 49.9% 87.2% 0% 4.93% Example 16 68.7% 99.5 50.2% 80.4% 0% 4.86% Example 17 69.2% 99.5 52.3% 77.5% 0% 4.75% Example 18 67.3% 99.5 53.7% 76.3% 0% 4.71% Example 19 68.9% 99.5 56.3% 78.1% 0% 3.89% Comparative Example 1 68.5% 99.2% 42.8% 75.3% 0% 0.56% Comparative Example 2 45.2% 98.5% 56.3% 82.6% 0% 1.34% Comparative Example 3 57.8% 99.0% 54.2% 76.5% 10% -1.11% Comparative Example 4 65.3% 98.9% 44.15% 74.5% 5% -3.61% Regarding the data in the table, the hair regrowth rate is compared with the blank group that did not use this embodiment, and the comparison of hair length is for reference only; Further explanation is needed regarding the data in the table. The maximum value represented by the data in the experimental data table is 99.5%. As can be seen from the table, the scalp microecological hair follicle conditioning solution prepared in Example 1 has the best comprehensive performance, with a sebum secretion inhibition rate of 65.3%, a Malassezia inhibition rate of 99.5%, a scalp barrier repair rate of 56.3%, an 8-hour moisturizing duration of 82.2%, and 0% irritation. This indicates that when the four functional components are combined in the optimal ratio, they can achieve synergistic effects of oil removal, antibacterial, repair, moisturizing, and hypoallergenic properties, fully meeting the needs of scalp conditioning.
[0024] Examples 2-7 focus on adjusting the ingredients of the oil-control composition: Example 2, without panthenol, the scalp barrier repair rate decreased to 46.9%, significantly lower than Example 1, indicating that panthenol plays a key role in scalp barrier repair and forms a synergistic moisturizing and repairing effect with ceramide trioxide; Example 3, without ceramide trioxide, the sebum secretion inhibition rate decreased to 57.7%, confirming the synergistic oil-control efficacy of ceramide trioxide with niacinamide and prebiotics; Examples 5-6, by adjusting the ratio of niacinamide and prebiotics, the sebum secretion inhibition rate increased to 68.4%-70.1%, indicating that increasing the proportion of niacinamide or prebiotics within a reasonable range can enhance the oil-control effect. However, in Example 7, after excessively increasing the proportion of ceramide trioxide, the sebum inhibition rate and barrier repair rate both decreased to 54.6% and 43.3%, respectively, indicating that the ingredient ratio needs to be strictly controlled to avoid efficacy conflicts.
[0025] Examples 8-11: Optimization of the proportions of the hypoallergenic composition: Examples 8-10: Adjusting the ratio of Platycladus orientalis leaf extract to Lactobacillus fermentation product resulted in sebum secretion inhibition rates fluctuating between 38.9% and 57.9%. In Example 11, when the ratio was adjusted to 2%:1%, the scalp barrier repair rate reached 60.2%, which was better than Example 1. This indicates that the ratio of Platycladus orientalis leaf extract to Lactobacillus fermentation product directly affects the scalp barrier repair effect. A reasonable ratio can enhance the soothing and repairing effects. Furthermore, all examples showed 0% irritation, confirming the mild nature of the hypoallergenic composition.
[0026] Examples 12-15 focus on component changes in the adaptable mixed composition: Examples 13-14 adjusted the proportion of meadowsweet extract, increasing the 8-hour moisturizing duration to 85.9%-86.7%; Example 15 increased the proportion of clomiphene, achieving a moisturizing duration of 87.2%, and all examples maintained a Malassezia inhibition rate of 99.5%, indicating that meadowsweet extract and clomiphene can not only effectively inhibit Malassezia, but also synergistically enhance the moisturizing effect with sodium hyaluronate and panthenol, without increasing irritation, ensuring the balance between product gentleness and antibacterial properties.
[0027] Examples 16-19: Adjustment of the proportion of the anti-hair loss composition: Examples 17-19: Increasing the proportion of caffeine or prebiotics maintained the sebum secretion inhibition rate at 67.3%-69.2%, and increased the scalp barrier repair rate to 52.3%-56.3%. This indicates that the synergistic effect of caffeine and prebiotics can simultaneously optimize the oil removal and barrier repair effects, laying the foundation for the anti-hair loss efficacy, without affecting other product properties, demonstrating the adaptability and flexibility of the formula.
[0028] Comparative Examples 1-4 each lacked one of the four major functional compositions: Comparative Example 1 lacked the oil-removing composition, resulting in a scalp barrier repair rate of 42.8% and a moisturizing duration of 75.3%, indicating that panthenol and ceramides in the oil-removing composition have auxiliary effects on moisturizing and barrier repair; Comparative Example 2 lacked the hypoallergenic composition, resulting in a sebum secretion inhibition rate of only 45.2%, significantly lower than Example 1, confirming the positive effects of Platycladus orientalis leaf extract and Lactobacillus fermentation products in the hypoallergenic composition on synergistic oil removal; Comparative Example 3 lacked the suitable mixed composition, resulting in 10% irritation and a decrease in moisturizing duration of 76.5%, indicating that meadowsweet extract and clomiphene citrate in the suitable mixed composition are key to ensuring the product's gentleness and moisturizing properties; Comparative Example 4 lacked the suitable anti-hair loss composition, resulting in a scalp barrier repair rate of 44.15%, indicating that biotin and ceramides in the anti-hair loss composition play an important role in scalp barrier repair. In summary, the four functional components are indispensable, and their synergistic effect is the core of the product's multifunctional, gentle, and efficient conditioning. The reasonable ingredient ratio and process design ensure the product's comprehensive performance advantages.
[0029] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.
Claims
1. A scalp microecology follicle conditioner, characterized by: The deoiling composition 6.5%, the low sensitivity composition 2.5%, the adaptive mixed composition 6.5%, the adaptive anti-shedding composition 6.5%, disodium EDTA 0.1%, glycerol 3%, triethanolamine 0.2% and deionized water 74.7%.
2. A scalp microecological follicle conditioning liquid according to claim 1, characterized in that: The deoiling composition nicotinamide 2%, prebiotic 1%, ceramide tri 0.3%, panthenol 1%, deionized water 95.7%.
3. A scalp microecological follicle conditioning liquid according to claim 2, characterized in that: The preparation steps of the deoiling composition are as follows: A1, mix nicotinamide with prebiotic, grind into powder through 80 mesh sieve, add 47.85% deionized water, stir at 28℃, 60r / min for 10min, until completely dissolved; A2, adjust the system pH to 5.8 with citric acid, add ceramide tri, stir for 5min, then add panthenol, continue to stir for 15min; A3, add the remaining 47.85% deionized water, increase the stirring speed to 80r / min, continue to stir for 20min; A4, stand for 30min, filter through 0.22μm filter membrane to obtain the deoiling composition.
4. The scalp microecological hair follicle conditioning liquid according to claim 1, characterized in that: The low sensitivity composition includes cypress leaf extract 3%, lactobacillus fermentation product 2%, ceramide tri 0.2%, sodium hyaluronate 0.2%, deionized water 94.6%.
5. A scalp microecosystem hair follicle conditioning liquid according to claim 4, characterized in that: The preparation method of the low sensitivity composition is as follows: B1, mix cypress leaf extract with lactobacillus fermentation product, grind into powder through 80 mesh sieve, add 47.3% deionized water, stir at 25℃, 60r / min for 10min, until completely dissolved; B2, adjust the system pH to 6.2 with citric acid, add ceramide tri, stir for 5min, then add sodium hyaluronate, continue to stir for 15min; B3, add the remaining 47.3% deionized water, increase the stirring speed to 80r / min, continue to stir for 20min; B4, stand for 30min, filter through 0.22μm filter membrane to obtain the low sensitivity composition.
6. A scalp microecosystem hair follicle conditioning liquid according to claim 1, characterized in that: The adaptive mixed composition includes spirea ulmaria extract 2%, climbazole 0.3%, panthenol 2%, sodium hyaluronate 0.1%, deionized water 95.6%.
7. A scalp microecosystem follicle conditioning fluid according to claim 6, wherein: The preparation method of the adaptive mixed composition is as follows: C1, mix spirea ulmaria extract with climbazole, grind into powder through 80 mesh sieve, add 47.8% deionized water, stir at 30℃, 60r / min for 10min, until completely dissolved; C2, adjust the system pH to 6.0 with citric acid, add panthenol, stir for 5min, then add sodium hyaluronate, continue to stir for 15min; C3, add the remaining 47.8% deionized water, increase the stirring speed to 80r / min, continue to stir for 20min; C4, stand for 30min, filter through 0.22μm filter membrane to obtain the adaptive mixed composition.
8. A scalp microecosystem hair follicle conditioning liquid according to claim 1, characterized in that: The adaptive anti-shedding composition includes caffeine 2%, prebiotic 1.5%, ceramide tri 0.3%, biotin 0.02%, deionized water 96.18%.
9. A scalp microecosystem follicle conditioning fluid according to claim 8, wherein: The preparation steps of the adaptive anti-shedding composition are as follows: D1, mix caffeine with prebiotics, grind into powder through 80 mesh sieve, add 48.09% deionized water, stir at 27℃, 60r / min for 10min until completely dissolved; D2, adjust the pH of the system to 5.6 with citric acid, add ceramide three, stir for 5min, then add biotin, continue to stir for 15min; D3, add the remaining 48.09% deionized water, increase the stirring speed to 80r / min, continue to stir for 20min; D4, stand for 30min, filter through 0.22μm filter membrane to obtain the adaptive anti-shedding composition.
10. A method of preparing a scalp microecosystem follicular conditioning fluid according to any one of claims 1 to 8, characterized in that: Including the following steps: S1, pretreatment preparation: place the oil composition 6.5%, the low sensitivity composition 2.5%, the adaptive mixed composition 6.5%, and the adaptive anti-shedding composition 6.5% in a 25℃ constant temperature environment for 30min to balance the temperature; S2, preparation of base solvent: take the formula amount of 74.7% deionized water, add 0.1% disodium EDTA, stir at 30℃, 60r / min for 5min until the disodium EDTA is completely dissolved; then add 3% glycerol, continue to stir for 10min to form a uniform base solvent system; S3, step-by-step mixing of functional ingredients: keep the stirring speed at 60r / min, first slowly add 6.5% oil-free composition, stir for 15min until completely dispersed; then add 2.5% low sensitivity composition, stir for 10min; then add 6.5% adaptive mixed composition and 6.5% adaptive anti-shedding composition in turn, stir for 10min after adding each one to ensure that the functional ingredients are gradually integrated and avoid active conflict caused by excessive local concentration; S4, pH balance adjustment: use citric acid and triethanolamine to adjust the pH of the system: first add 10% citric acid solution to preliminarily adjust the pH to 5.5-5.6, then add 5% triethanolamine solution to fine-tune the pH to 5.8-6.0, keep the stirring speed at 60r / min during the adjustment process, continue to stir for 15min after the adjustment is completed; S5, strengthen dispersion and stabilization: increase the stirring speed to 85r / min, continue to stir for 25min to make the system fully homogeneous; then stop stirring, stand for 40min in a 25℃ constant temperature environment to release the residual bubbles in the system; S6, fine filtration and finished product: fine filter the system after standing through 0.22μm polyether sulfone filter membrane to remove possible trace impurities or particles that have not completely dissolved; collect the filtered liquid, which is the scalp micro-ecological hair follicle conditioner.