Soothing and repairing composition and application thereof

Abstract

The invention provides a soothing and repairing composition and application thereof, and relates to the technical field of cosmetics. The soothing and repairing composition is prepared from flat-core wood oil, a citrus fruit extract, a spirulina maxima extract and a dracocephalum dracocephalum extract. The composition obtained by compounding the extracts through multiple experimental researches has excellent soothing and repairing effects, is mild and non-irritant, and has a good popularization and application prospect.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of cosmetics, in particular to a soothing and repairing composition and application thereof. BACKGROUND

[0002] In the field of cosmetics, soothing and repairing for sensitive skin has always been an important research direction. People with sensitive skin face many skin problems, such as skin being easily irritated by external stimuli, redness, itching, stinging, dryness, desquamation, impaired skin barrier function, accelerated water loss, and weak resistance to the external environment. These problems not only affect the appearance of the skin, but also bring discomfort to the user and reduce the quality of life.

[0003] Currently, existing cosmetics for soothing and repairing on the market have many shortcomings. On the one hand, many products only contain a single soothing or repairing ingredient, with a single target point, making it difficult to comprehensively care for sensitive skin from multiple aspects. For example, some products only rely on simple plant oils to moisturize the skin, but have limited effect on relieving skin inflammation and repairing the skin barrier; other products may only focus on cell repair, but ignore the immediate soothing effect of external stimuli. On the other hand, although some products claim to have soothing and repairing effects, the actual effect is not significant, and cannot meet the needs of people with sensitive skin. Moreover, some products may contain potentially irritating ingredients, which may further exacerbate the symptoms of sensitive skin and cause damage to the skin.

[0004] Based on the shortcomings of the prior art, the present application aims to provide a soothing and repairing composition and application thereof to solve the above problems and provide a more effective care solution for sensitive skin. SUMMARY

[0005] To solve the shortcomings of the prior art, the present application aims to provide a soothing and repairing composition and application thereof, which includes flat core wood oil, citrus fruit extract, giant spirulina extract, and radix salacia extract. The above composition has excellent soothing and repairing effects on the skin through multi-target synergistic effect, can effectively inhibit hyaluronidase activity, and increase the proliferation rate of HaCaT cells, and is suitable for sensitive skin.

[0006] The technical solutions adopted by the present application to achieve the above-mentioned purposes are as follows: In a first aspect, the present application provides a soothing and repairing composition, which includes the following components by mass: Flat core wood oil: 0.5-10 parts; Citrus fruit extract: 0.2-4 parts; Giant spirulina extract: 0.5-10 parts; Radix salacia extract: 0.1-1 part.

[0007] wherein: The unsaturated fatty acids and phytosterols (such as β-sitosterol, campesterol, etc.) in the Pouteria caimito oil are similar to the skin structure, can be embedded in the lipid bilayer of the stratum corneum, optimize the lipid arrangement and density, reduce the trans-epidermal water loss (TEWL), and relieve dryness and itching from the structural level; the phytosterols and polyphenols synergistically neutralize free radicals, inhibit hyaluronidase and elastase, reduce matrix degradation and inflammation amplification caused by environmental stress; animal models show that it has a promoting effect on skin tissue repair, and provides a stable soothing background for sensitive skin.

[0008] The citrus fruit extract contains flavonoids, vitamin C, and various antioxidants, which can scavenge active oxygen and reduce oxidative stress; inhibit hyaluronidase, soothe the skin, and provide long-lasting hydration.

[0009] The Spirulina maxima extract is rich in natural 2α-glycosylglycerol, which can promote the expression of keratinocyte AQP-3 (aquaporin-3), increase the water transport and water content of the epidermis, and relieve tightness and irritation caused by dryness.

[0010] The extract of Morinda officinalis contains flavonoids, proanthocyanidins, catechins, and other polyphenol systems, which can neutralize free radicals and inhibit oxidative stress, thereby reducing the release of inflammatory mediators and relieving redness, heat, and other sensitive symptoms; in addition, the extract of Morinda officinalis can stimulate skin cell regeneration and enhance the skin barrier.

[0011] The present application has found that the combination of the above components has a synergistic effect and can achieve excellent soothing and repairing effects.

[0012] As a preferred embodiment of the soothing and repairing composition of the present application, the composition comprises the following components by mass: Pouteria caimito oil: 3-5 parts; Citrus fruit extract: 0.5-2 parts; Spirulina maxima extract: 1-3 parts; Morinda officinalis extract: 0.5-0.7 parts.

[0013] The present application has found that the mass of each component in the composition will affect the performance of the composition, and when the mass of the components is further selected within the above range (including the end point values), the soothing and repairing performance of the obtained composition is better.

[0014] As the most preferred embodiment of the soothing and repairing composition of the present application, the composition comprises the following components by mass: Pouteria caimito oil: 4 parts; Citrus fruit extract: 1 part; Spirulina maxima extract: 2 parts; Extract of Radix Morindae Officinalis: 0.6 parts.

[0015] The present application studies and finds that the mass fraction of each component in the composition will affect the performance of the composition, and when the mass fraction of the components is further selected in the above mass fraction, the soothing and repairing performance of the obtained composition is optimal.

[0016] In a second aspect, the present application provides the use of the soothing and repairing composition of the first aspect in the preparation of a cosmetic product with soothing and repairing effects.

[0017] Preferably, the dosage form of the cosmetic product with soothing and repairing effects is at least one of emulsion, essence, serum, cream, and spray.

[0018] In a third aspect, the present application provides an emulsion with soothing and repairing effects, which comprises 0.1-8wt% of the soothing and repairing composition of the first aspect.

[0019] Preferably, the emulsion with soothing and repairing effects further comprises a humectant, a preservative, a surfactant, an oil agent, a thickening agent, and a solvent.

[0020] Preferably, the humectant comprises at least one of sodium hyaluronate, glycerol, and mannitol.

[0021] Preferably, the surfactant is at least one of cocamidopropyl betaine, sucrose ester, rhamnolipid, and sophorolipid. Preferably, the preservative comprises at least one of phenoxyethanol and hydroxyacetophenone. Preferably, the oil agent is at least one of sunflower seed oil and jojoba oil. Preferably, the thickening agent is at least one of carrageenan, guar gum, and xanthan gum. Preferably, the solvent is deionized water.

[0022] Compared with the prior art, the present application has the following beneficial effects: The soothing and repairing composition of the present application forms a unique synergistic action mechanism through the scientific combination of the extract of Rhamnus utilis, the extract of Citrus fruit, the extract of Spirulina maxima, and the extract of Radix Morindae Officinalis: Synergistic effect of barrier repair and cell regeneration: The extract of Spirulina maxima strengthens the epidermal lipid barrier function by promoting the expression of key proteins in keratinocyte differentiation, and the extract of Radix Morindae Officinalis activates the migration activity of skin cells to accelerate the wound closure process. The two components synergistically construct a positive cycle of "physical barrier reconstruction-cell regeneration supplement", which significantly improves the self-repairing ability of the skin.

[0023] Targeted regulation of hyaluronidase activity: Flat core wood oil, citrus fruit extract and great spirulina extract form complex inhibitors through intermolecular interaction, specifically bind to the active center of hyaluronidase, significantly delay the degradation rate of hyaluronic acid, and maintain the long-term water state of the skin.

[0024] The four components are used together to form a closed-loop mechanism through optimizing the permeability of stratum corneum, regulating the expression of keratinocyte-related proteins, promoting skin cell regeneration, inhibiting hyaluronidase, etc., effectively reducing the skin water loss rate, improving the fragile state of sensitive skin, and providing an innovative solution for sensitive skin repair based on barrier function repair and cell regeneration synergy. DETAILED DESCRIPTION

[0025] In order to better understand the present application, the present application will be further described below in conjunction with specific examples, wherein the terms "composition" and "emulsion" used are for describing specific embodiments and do not constitute a limitation on the scope of protection of the present application.

[0026] The experimental methods in the following examples not specified in the specific conditions are usually carried out according to the conventional conditions, or according to the conditions recommended by the manufacturer. Unless otherwise specified, the percentages and mass fractions are calculated.

[0027] Some raw materials and sources are as follows: Flat core wood oil: purchased from Lijiang Yongsheng Biantun Food and Health Garden Co., Ltd.; Citrus fruit extract: purchased from Guangzhou Gaye Biotechnology Co., Ltd.; Great spirulina extract: purchased from Guangzhou Nuoren Biotechnology Co., Ltd.; Extract of Herba Lycopi: purchased from Beijing Shangjietianlan Technology Co., Ltd.

[0028] The remaining raw materials and reagents are commercially available.

[0029] The components and mass fractions of the soothing and repairing composition are as follows: Composition 1: Flat core wood oil: 4 parts; Citrus fruit extract: 1 part; Great spirulina extract: 2 parts; Extract of Herba Lycopi: 0.6 parts.

[0030] Composition 2: Flat core wood oil: 3 parts; Citrus fruit extract: 0.5 parts; Great spirulina extract: 1 part; Extract of Herba Lycopi: 0.5 parts.

[0031] Composition 3: Flat core wood oil: 5 parts; Citrus aurantium extract: 2 parts; Spirulina maxima extract: 3 parts; Herba epimedii extract: 0.7 parts.

[0032] Composition 4: Bixa orellana oil: 0.5 parts; Citrus aurantium extract: 0.2 parts; Spirulina maxima extract: 0.5 parts; Herba epimedii extract: 0.1 parts.

[0033] Composition 5: Bixa orellana oil: 10 parts; Citrus aurantium extract: 4 parts; Spirulina maxima extract: 10 parts; Herba epimedii extract: 1 part.

[0034] Composition 1: Different from Composition 1, Bixa orellana oil is absent, and Citrus aurantium extract, Spirulina maxima extract, and Herba epimedii extract are supplemented in a mass ratio of 1:2:0.6.

[0035] Composition 2: Different from Composition 1, Citrus aurantium extract is absent, and Bixa orellana oil, Spirulina maxima extract, and Herba epimedii extract are supplemented in a mass ratio of 4:2:0.6.

[0036] Composition 3: Different from Composition 1, Spirulina maxima extract is absent, and Bixa orellana oil, Citrus aurantium extract, and Herba epimedii extract are supplemented in a mass ratio of 4:1:0.6.

[0037] Composition 4: Different from Composition 1, Herba epimedii extract is absent, and Bixa orellana oil, Citrus aurantium extract, and Spirulina maxima extract are supplemented in a mass ratio of 4:1:2.

[0038] Composition 5: Bixa orellana oil: 0.4 parts; Citrus aurantium extract: 5 parts; Spirulina maxima extract: 0.3 parts; Herba epimedii extract: 5 parts.

[0039] The soothing repair emulsion, its components and mass percentages are as follows: Emulsion 1: Composition 1: 4wt%; Humectant: 3wt%; Surfactant: 0.2wt%; Preservative: 0.1 wt%; Oil agent: 0.5 wt%; Thickening agent: 0.2 wt%; Solvent to 100 wt%; Wherein the humectant is glycerin; the surfactant is cocamidopropyl betaine; the preservative is phenoxyethanol; the oil agent is jojoba oil; the thickening agent is carrageenan; the solvent is deionized water.

[0040] Emulsion 2: Composition 1: 0.1 wt%; Humectant: 3 wt%; Surfactant: 0.2 wt%; Preservative: 0.1 wt%; Oil agent: 0.5 wt%; Thickening agent: 0.2 wt%; Solvent to 100 wt%; Wherein the humectant is glycerin; the surfactant is cocamidopropyl betaine; the preservative is phenoxyethanol; the oil agent is jojoba oil; the thickening agent is carrageenan; the solvent is deionized water.

[0041] Emulsion 3: Composition 1: 8 wt%; Humectant: 3 wt%; Surfactant: 0.2 wt%; Preservative: 0.1 wt%; Oil agent: 0.5 wt%; Thickening agent: 0.2 wt%; Solvent to 100 wt%; Wherein the humectant is glycerin; the surfactant is cocamidopropyl betaine; the preservative is phenoxyethanol; the oil agent is jojoba oil; the thickening agent is carrageenan; the solvent is deionized water.

[0042] Emulsion 4: Different from emulsion 1, composition 2 is used to replace composition 1 in equal mass, and the rest of the components and mass percentages are the same as emulsion 1.

[0043] Emulsion 5: Different from emulsion 1, composition 3 is used to replace composition 1 in equal mass, and the rest of the components and mass percentages are the same as emulsion 1.

[0044] Emulsion 6: Different from emulsion 1, composition 4 is used to replace composition 1 in equal mass, and the rest of the components and mass percentages are the same as emulsion 1.

[0045] Emulsion 7: The composition 5 is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0046] The comparative emulsion 1 is: The composition ① is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0047] The comparative emulsion 2 is: The composition ② is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0048] The comparative emulsion 3 is: The composition ③ is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0049] The comparative emulsion 4 is: The composition ④ is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0050] The comparative emulsion 5 is: The composition ⑤ is used to replace the composition 1 in the same amount, and the other components and mass percentages are the same as those of the emulsion 1.

[0051] The blank emulsion is: The humectant is 3wt%; The surfactant is 0.2wt%; The preservative is 0.1wt%; The oil agent is 0.5wt%; The thickening agent is 0.2wt%; The solvent is supplemented to 100wt%; The humectant is glycerol, the surfactant is cocamidopropyl betaine, the preservative is phenoxyethanol, the oil agent is jojoba oil, the thickening agent is carrageenan, and the solvent is deionized water.

[0052] The preparation method of the emulsion 1 is as follows: S1: uniformly mix the composition, the oil agent, the surfactant, and 1 / 2 deionized water to obtain a mixed liquid 1; S2: uniformly mix the humectant, the preservative, and the remaining deionized water to obtain a mixed liquid 2; S3: uniformly mix the mixed liquid 1, the mixed liquid 2, and the thickening agent to obtain the emulsion.

[0053] The preparation methods of the emulsions 2-7 and the comparative emulsions 1-5 are the same as those of the emulsion 1.

[0054] The preparation method of the blank emulsion is as follows: S1: mix the oil agent, the surfactant and 1 / 2 deionized water uniformly to obtain a mixed solution 1; S2: mix the moisturizing agent, the preservative and the remaining deionized water uniformly to obtain a mixed solution 2; S3: mix the mixed solution 1, the mixed solution 2 and the thickening agent uniformly to obtain an emulsion.

[0055] Test 1: safety test The irritation of the cosmetic was evaluated according to the Technical Standard for Safety of Cosmetics (2015) as the reference standard. The test method was a skin patch test, and the test was performed on volunteers aged 16-65 years randomly distributed. The volunteers were grouped according to the number of test substances, and each group corresponded to one test substance. Each group had 30 people.

[0056] Test substance: emulsion 1-7, comparative emulsion 1-5 and blank emulsion.

[0057] Test method: the test substance was placed in a patch tester, and the amount was 0.020-0.025 g. The patch tester with the test substance was covered with a non-irritating cloth-based adhesive tape on the back or forearm of the volunteer. The skin surface was evenly attached by pressing it with the palm for 24 hours. After 30 minutes of removing the test patch, the skin reaction was observed after the indentation disappeared. If the result was negative, the observation was performed again at 24 hours and 48 hours after the patch test.

[0058] Evaluation criteria: 0: negative reaction; 1: suspicious reaction, only weak erythema; 2: weak positive reaction, erythema, infiltration, edema, and possibly papules; 3: strong positive reaction, erythema, infiltration, edema, and possibly papules, and the reaction may exceed the test area; 4: very strong positive reaction, obvious erythema, severe infiltration, edema, and confluent blisters, and the reaction exceeds the test area.

[0059] Test result: the skin reaction of all volunteers was negative.

[0060] Test 2: verification of emulsion soothing efficacy Hyaluronic acid, also known as hyaluronic acid, is a powerful moisturizer. It can attract and lock in moisture, keeping the skin moist, improving dry, rough and water-deficient skin conditions; and hyaluronic acid can also enhance the biological activity of cells, and has a strong synergistic effect on repairing and protecting the skin. Therefore, by inhibiting hyaluronidase, the decomposition rate of hyaluronic acid in the skin is reduced, thereby realizing the soothing, long-acting water and moisture retention and repair of the skin.

[0061] Test sample: emulsion 1-7, comparative emulsion 1-5 and blank emulsion. Reagent preparation: Hyaluronidase solution: 500 U / mL, prepared fresh, using acetic acid buffer as solvent; Sodium hyaluronate solution: 0.5 mg / mL, using acetic acid buffer as solvent; Acetic acid buffer: 0.2 mol / L acetic acid 4.8 mL and 0.2 mol / L sodium acetate 45.2 mL, mixed and diluted to 100 mL to prepare a pH=5.6 acetic acid buffer; Acetylacetone solution: 50 mL 1.0 mol / L sodium carbonate solution and 3.5 mL acetylacetone are mixed evenly (prepared fresh); DAB reagent: 0.8 g p-dimethylaminobenzaldehyde is dissolved in a mixture of 15 mL concentrated hydrochloric acid and 15 mL anhydrous ethanol, mixed evenly, and the mass concentration of the concentrated hydrochloric acid is 37%; CaCl2 solution: 2.5 mol / L; NaOH solution: 5 mol / L.

[0062] (1) Take four clean test tubes, respectively labeled A, B, C, and D. Add 50 μL of the sample to be tested to tubes A and B, and 50 μL of distilled water to tubes C and D. Add 50 μL of 500 U / mL hyaluronidase solution to tubes A and C, and 50 μL of pH=5.6 acetic acid buffer to tubes B and D. Place the test tubes in a 37 ℃ incubator for 20 min. (2) Add 10 μL of 2.5 mol / L CaCl2 solution to each of the four test tubes, and then place them in a 37 ℃ incubator for 20 min. (3) Add 50 μL of 0.5 mg / mL sodium hyaluronate solution to tubes A and C, and 50 μL of pH=5.6 acetic acid buffer to tubes B and D. Place the test tubes in a 37 ℃ incubator for 40 min, then remove and let stand at room temperature for 10 min. (4) Add 50 μL of distilled water, 10 μL of 5 mol / L NaOH solution, and 50 μL of acetylacetone solution to each of the four test tubes. Place the test tubes in a boiling water bath for 30 min, then in an ice bath for 10 min, and finally at room temperature for 10 min. (5) Add 100 μL of P-DAB reagent to each test tube, then measure the absorbance at 530 nm using an enzyme marker. Hyaluronidase inhibition rate (%) = ; In the formula: A is the OD value of the solution in test tube A; B is the OD value of the solution in test tube B; C is the OD value of the solution in test tube C; and D is the OD value of the solution in test tube D.

[0063] Table 1. Verification of the soothing efficacy of the lotion Group Hyaluronidase inhibition rate / % Emulsion 1 65.22 Emulsion 2 47.26 Emulsion 3 67.33 Emulsion 4 61.57 Emulsion 5 63.94 Emulsion 6 64.16 Emulsion 7 63.97 Comparative emulsion 1 51.29 Comparative emulsion 2 48.26 Comparative emulsion 3 44.67 Comparative emulsion 4 53.39 Comparative emulsion 5 57.18 Blank emulsion 4.93 According to the results of emulsions 1-7, comparative emulsions 1-5, and blank emulsion in Table 1, the composition defined in this invention has a certain inhibitory effect on hyaluronidase, indicating that it has a certain soothing effect. Specifically, according to the results of emulsion 1 and comparative emulsions 1-4, when the four raw materials defined in the composition of this invention are used together in the mass proportions defined in this invention, the inhibitory effect on hyaluronidase is greatly enhanced, indicating that there is a significant synergistic effect among the four raw materials in the composition of this invention. According to the results of emulsions 1, 4-7, and comparative emulsion 5, when the raw materials in the composition defined in this invention are used in combination within the mass proportions defined in this invention, the inhibitory effect on hyaluronidase activity is better.

[0064] Experiment 3: Verification of the repairing efficacy of the lotion Cell migration plays a significant role in wound healing and skin repair. During wound healing, cell migration is a crucial step in the process of epidermal cells covering the wound; therefore, the higher the cell migration rate, the faster the wound heals. In scratch assays, cell migration rate can be used to evaluate the repair efficacy of test samples.

[0065] Press 1×10 6 HaCaT cells were seeded at a density of 1 unit into 12-well plates and incubated overnight at 37°C with 5% CO2. When the cell coverage in the 12-well plates reached 80±5%, scratching was performed on the sample group and the blank control group. After scratching, the cells were washed with PBS to remove dead cells, and then fresh SCF-free keratinocyte culture medium was added. 50 μL of the experimental sample (emulsion 1-7, control emulsion 1-5, and blank emulsion) was added to each well, with an equal volume of deionized sterile water as a blank control. The images were taken using an inverted microscope, and the cells were incubated at 37°C with 5% CO2 for 24 hours. The images were taken again, and the data were statistically analyzed using ImageJ software. Three parallel experiments were performed for each sample group and the blank control group. The average cell migration rate was calculated using the following formula, and the results are shown in Table 2.

[0066] Cell migration rate / % = (Scratch area before experiment - Scratch area after experiment) / Scratch area before experiment × 100% Average cell migration rate (%) = Sum of cell migration rates in parallel experiments for the same sample / Number of parallel experiments Table 2. Verification of the repairing efficacy of the emulsion Group Cell average migration rate / % Emulsion 1 62.17 Emulsion 2 41.29 Emulsion 3 65.51 Emulsion 4 57.46 Emulsion 5 59.51 Emulsion 6 60.74 Emulsion 7 61.93 Comparative emulsion 1 49.36 Comparative emulsion 2 42.91 Comparative emulsion 3 43.29 Comparative emulsion 4 51.14 Comparative emulsion 5 54.37 Blank emulsion 5.72 Blank control 1.68 As can be seen from the results of emulsions 1-7, comparative emulsions 1-5 and blank emulsion in Table 2, the composition defined in the application has a strong cell migration rate, indicating that it has a certain repair effect; as can be seen from the results of emulsion 1 and comparative emulsions 1-4, the four raw materials defined in the composition of the application have the best effect on the promotion of cell migration rate when used together after compounding in the mass fraction defined in the application, indicating that the four raw materials in the composition of the application have a significant synergistic effect; as can be seen from the results of emulsions 1, 4-7 and comparative emulsion 5, the raw materials in the composition defined in the application have the best effect on the promotion of cell migration rate when compounded in the mass fraction defined in the application.

[0067] Test 4: Human efficacy test Trans Epidermal Water Loss (TEWL) is an important parameter for evaluating the barrier function of the skin, which represents the evaporation and loss of water in the deep dermis through the epidermis. The higher the trans epidermal water loss rate, the more water is lost through the skin, indicating that the skin barrier is poor.

[0068] Trans epidermal water loss is closely related to the hydration of the stratum corneum and is a commonly used index for reflecting the barrier function of the stratum corneum. In the development process of cosmetics, the TEWL value of skin water loss can be tested to evaluate the efficacy of moisturizing cosmetics. In addition, trans epidermal water loss can also be applied to allergic patch test, contact dermatitis, physical therapy, burn and monitoring of new tissue, and timely detection of whether the barrier function of the skin has been damaged.

[0069] Test sample: emulsions 1-7, comparative emulsions 1-5, blank emulsion.

[0070] Trans epidermal water loss was tested by Trans Epidermal Water Loss (TEWL) test; a TM300 tester from Germany's Courage & Khazaka company was used for testing, specifically: 30 women aged 20 to 40 without skin diseases were randomly selected as test subjects for each test sample; the test subjects took the test sample (0.5 ml) twice a day and evenly applied it to the inner side of the forearm, then the same tester tested the trans epidermal water loss (TEWL value) of the area where the test sample was applied after 0 weeks and 4 weeks, respectively; the TEWL value average decrease rate was calculated by the following formula, and the results are shown in Table 3.

[0071] Formula: TEWL decrease rate / % = ; In the formula: A0 is the TEWL value at 0 weeks; A4 is the TEWL value at 4 weeks.

[0072] The average decrease rate of the TEWL value is a positive value, indicating that the skin barrier is repaired, otherwise, the skin barrier is not repaired; and the greater the average decrease rate of the TEWL value, the better the repair effect of the skin barrier. The calculation formula of the average decrease rate of the TEWL value is as follows: The average decrease rate of the TEWL value (%) = the sum of the decrease rates of the TEWL values of each group / the number of subjects in each group.

[0073] Table 3: Average decrease rate of the TEWL value Group TEWL average decrease rate / % Emulsion 1 16.2 Emulsion 2 9.1 Emulsion 3 17.3 Emulsion 4 13.6 Emulsion 5 14.9 Emulsion 6 15.3 Emulsion 7 15.7 Comparative emulsion 1 11.2 Comparative emulsion 2 9.8 Comparative emulsion 3 9.5 Comparative emulsion 4 11.4 Comparative emulsion 5 12.7 Blank emulsion 2.4 According to the results in Table 3, it can be seen that the emulsion provided by the present application can significantly reduce sebum secretion and significantly down-regulate the TWEL value, which indicates that the emulsion provided by the present application has certain soothing and repairing effects, which is consistent with the foregoing test results; according to the results of emulsion 1-7, comparative emulsion 1-5 and blank emulsion, it can be seen that the composition in the present application makes a non-negligible contribution to the improvement of the average decrease rate of TEWL, specifically, according to the results of emulsion 1 and comparative emulsion 1-5, it can be seen that when the raw materials and mass fraction ratio of the composition contained in the emulsion are within the range defined in the present application, the average decrease rate of TEWL is significantly improved.

[0074] The above-described embodiments are part of the embodiments of the present application, rather than all the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the claimed application, but only represents selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

Claims

1. A soothing repair composition characterized in that, The composition comprises the following components by mass parts: Podozogenyl oil: 0.5-10 parts; Citrus fruit extract: 0.2-4 parts; Extremely large spirulina extract: 0.5-10 parts; Herba epimedii extract: 0.1-1 parts.

2. The composition of claim 1, wherein, The composition comprises the following components by mass parts: Podozogenyl oil: 3-5 parts; Citrus fruit extract: 0.5-2 parts; Extremely large spirulina extract: 1-3 parts; Herba epimedii extract: 0.5-0.7 parts.

3. The composition of claim 1, wherein The composition comprises the following components by mass parts: Podozogenyl oil: 4 parts; Citrus fruit extract: 1 part; Extremely large spirulina extract: 2 parts; Herba epimedii extract: 0.6 parts.

4. Use of the composition according to any one of claims 1-3 in the preparation of a cosmetic product with soothing and repairing efficacy.

5. Use according to claim 4, characterized in that, The dosage form of the cosmetic product with soothing and repairing efficacy is at least one of emulsion, essence, serum, cream, and spray.

6. An emulsion having soothing and repairing efficacy, characterized in that it comprises: The emulsion comprises 0.1-8 wt% of the soothing and repairing composition according to any one of claims 1-3.

7. The emulsion of claim 6, wherein, It also comprises a humectant, a preservative, a surfactant, an oil agent, a thickening agent, and a solvent.

8. The emulsion of claim 7, wherein, The humectant is at least one of sodium hyaluronate, glycerol, and mannitol; the surfactant is at least one of cocamidopropyl betaine, sucrose ester, rhamnolipid, and sophorolipid.

9. The emulsion of claim 7, wherein, The preservative is at least one of phenoxyethanol and hydroxyacetophenone; the oil agent is at least one of sunflower seed oil and jojoba oil.

10. The emulsion of claim 7, wherein, The thickening agent is at least one of carrageenan, guar gum, and xanthan gum; and the solvent is deionized water.