Fluid vessel pump

Abstract

The invention relates to a fluid vascular pump. A fluid vessel pump may include a plurality of chambers that operate interactively to pump fluid in a vessel. For example, a vascular pump may include a first inflatable chamber structure configured to be implanted within a first fluid vessel and a second inflatable chamber structure configured to be implanted within a second fluid vessel adjacent the first fluid vessel. The first expandable chamber structure may be in fluid communication with the second expandable chamber structure. Compression of the first expandable chamber structure may cause expansion of the second expandable chamber structure.

Description

[0001] This application is a divisional application of the original application with the filing date of July 23, 2020, application number 2020800544150, and the title of “Fluid Vessel Pump”.

[0002] Cross Reference to Related Applications This application claims priority to U.S. Provisional Application No. 62 / 882,754, filed August 5, 2019, entitled “Fluid Vessel Pump”, the entirety of which is incorporated herein by reference. TECHNICAL FIELD

[0003] The present disclosure relates to the field of medical devices and procedures. BACKGROUND

[0004] Congestive heart failure (CHF) is a condition in which the heart is unable to adequately pump blood to other organs of the body. CHF is a progressive disease that can cause the heart muscle to weaken or stiffen over time, resulting in a decrease in cardiac output and can exacerbate symptoms of heart failure. In some cases of CHF, systemic fluid congestion that can lead to CHF is caused by right-sided heart failure. For example, the right side of the heart can be unable to efficiently return blood to the heart, for example, through the vena cava. This can result in shortness of breath, exercise intolerance, fatigue, elevated venous pressure, edema, hospitalization, or death. SUMMARY

[0005] Described herein are one or more methods and / or devices that facilitate an increase in fluid flow by using one or more inflatable chamber structures implantable in certain blood vessels and / or chambers of the human anatomy.

[0006] In some embodiments, the present disclosure relates to an intervascular fluid pump comprising: a first inflatable chamber structure configured to be implanted within a first fluid vessel; and a second inflatable chamber structure configured to be implanted within a second fluid vessel adjacent to the first fluid vessel. The second inflatable chamber structure extends longitudinally and is in fluid communication with the first inflatable chamber structure. In some embodiments, compression of the first inflatable chamber structure causes expansion of the second inflatable chamber structure.

[0007] In some embodiments, the intervascular fluid pump further comprises a first conduit structure having an hourglass-shaped profile and a longitudinally extending lumen, and a second conduit structure extending longitudinally and comprising one or more radially extending apertures. The second conduit structure is configured to house at least a portion of the first conduit structure and is longitudinally aligned with the first conduit structure. The second inflatable chamber structure is configured to be disposed between the first conduit structure and the second conduit structure.

[0008] In some embodiments, the intervascular fluid pump further includes a valve structure configured to be longitudinally aligned with the first conduit structure and configured to be disposed between the second inflatable chamber structure and the second conduit structure. The valve structure is configured to be radially displaced to occlude one or more apertures of the second conduit structure when the second inflatable chamber structure is inflated. In some embodiments, one or more of the second inflatable chamber structure and the valve structure have a tapered cylindrical shape. In some embodiments, the first conduit structure includes one or more one-way valves disposed in at least one end of the first conduit structure. In some embodiments, in the deployed state: the first conduit structure and the second conduit structure are disposed to form a suction cavity between the first conduit structure and the second conduit structure, and the second inflatable chamber structure is configured to radially inflate to push fluid in the suction cavity through the one or more one-way valves.

[0009] In some embodiments, one or more of the first inflatable chamber structure and the second inflatable chamber structure include a wireframe structure. In some embodiments, the intervascular fluid pump further includes a conduit structure connecting the first inflatable chamber structure to the second inflatable chamber structure with fluid.

[0010] In some embodiments, the disclosure relates to a method of increasing diastolic pressure, comprising: deploying a first inflatable chamber structure in a patient’s aorta, and deploying a second inflatable chamber structure in a patient’s inferior vena cava. The second inflatable chamber structure is in fluid communication with the first inflatable chamber structure through a conduit structure that extends through a wall in the aorta and a wall in the inferior vena cava.

[0011] In some embodiments, deploying the second inflatable chamber structure includes deploying the second inflatable chamber structure in the inferior vena cava to axially overlap at least a portion of renal vein input into the inferior vena cava. In some embodiments, the method further includes pumping blood from the renal veins into the inferior vena cava using the first inflatable chamber structure and the second inflatable chamber structure. In some embodiments, the pumping includes drawing blood from the renal veins into a suction cavity associated with the second inflatable chamber structure during diastole, and pumping blood out of the suction cavity during systole. In some embodiments, drawing blood into the suction cavity includes inflating the first inflatable chamber structure and deflating the second inflatable chamber structure, and pumping blood out of the suction cavity includes deflating the first inflatable chamber structure and inflating the second inflatable chamber structure.

[0012] In some embodiments, the method further includes advancing a guidewire through a wall of the inferior vena cava and a wall of the aorta at a location within a distance from the renal veins in the inferior vena cava. Deploying the first inflatable chamber structure in the aorta includes advancing a delivery catheter through the inferior vena cava into the aorta using the guidewire.

[0013] In some implementations, the present disclosure is directed to a blood vessel pump comprising a first inflatable chamber structure configured to be implanted within a first fluidic blood vessel, a second inflatable chamber structure configured to be in fluid communication with the first inflatable chamber structure, and an anchor structure configured to be implanted within a second fluidic blood vessel and to house at least a portion of the second inflatable chamber structure. In a deployed state, the second inflatable chamber structure is configured to inflate to fill at least a portion of a suction cavity within the anchor structure.

[0014] In some embodiments, the first fluidic blood vessel comprises an abdominal aorta and the second fluidic blood vessel comprises an inferior vena cava. In some embodiments, a cross-section of a first end of the anchor structure has a first diameter and a cross-section of a central portion of the anchor structure has a second diameter that is less than the first diameter. In some embodiments, one or more of the first inflatable chamber structure and the second inflatable chamber structure comprises a compliant balloon.

[0015] In some embodiments, the anchor structure comprises one or more one-way valves configured to allow fluid to flow from the suction cavity into the second fluidic blood vessel when deployed. In some embodiments, the blood vessel pump further comprises a valve structure configured to be disposed within the anchor structure with the anchor structure and to be radially displaced to occlude one or more apertures in the anchor structure when the second inflatable chamber structure inflates.

[0016] For purposes of summarizing the disclosure, certain aspects, advantages and novel features have been described. It is to be understood that not necessarily all such advantages can be achieved in accordance with any particular embodiment. Thus, embodiments disclosed can be executed in a manner that achieves or optimizes one advantage or a limited number of advantages as compared to currently known approaches. BRIEF DESCRIPTION OF DRAWINGS

[0017] Various embodiments in the drawings are described for illustrative purposes and are in no way to be construed as limiting the scope of the present disclosure. Furthermore, various features of different disclosed embodiments can be combined to form additional embodiments that are part of the present disclosure. Throughout the drawings, reference numerals can be repeated to indicate corresponding relationships between reference elements.

[0018] Figure 1 An example human anatomy is illustrated having various features relevant to certain aspects of the present disclosure, in which an example fluidic blood vessel pump is implanted.

[0019] Figure 2 An example device for pumping fluid is illustrated, according to one or more embodiments, including a first inflatable chamber structure and an anchor structure.

[0020] Figure 3A cross-sectional view of an aorta and inferior vena cava is illustrated with an example device implanted to pump blood, in accordance with one or more embodiments.

[0021] Figure 4-1 An example upper portion of a conduit structure is illustrated, in accordance with one or more embodiments.

[0022] Figure 4-2 An example lower portion of a conduit structure is illustrated, in accordance with one or more embodiments.

[0023] Figure 4-3 An example conduit structure is illustrated configured to be associated with another conduit structure, in accordance with one or more embodiments.

[0024] Figure 4-4 An example inflatable chamber structure is illustrated configured to be implemented with one or more conduit structures, in accordance with one or more embodiments.

[0025] Figure 4-5 An example valve structure is illustrated configured to be implemented with one or more conduit structures and inflatable chamber structures, in accordance with one or more embodiments.

[0026] Figure 4-6 An example inflatable chamber structure is illustrated configured to be connected to another inflatable chamber structure, in accordance with one or more embodiments.

[0027] Figure 5-1 An example device is illustrated pumping blood during diastole of a cardiac cycle, in accordance with one or more embodiments.

[0028] Figure 5-2 An example device is illustrated within human anatomy during diastole, in accordance with one or more embodiments.

[0029] Figure 5-3 A plot of aortic pressure and a point when aortic pressure is at a minimum is illustrated, in accordance with one or more embodiments.

[0030] Figure 6-1 An example device is illustrated pumping blood during systole of a cardiac cycle, in accordance with one or more embodiments.

[0031] Figure 6-2 An example device is illustrated within human anatomy during systole, in accordance with one or more embodiments.

[0032] Figure 6-3 A plot of aortic pressure and a point when aortic pressure is at a maximum is illustrated, in accordance with one or more embodiments.

[0033] Figure 7A FIG. illustrates a side view of an expandable chamber structure connected to another expandable chamber structure by a conduit structure, in accordance with one or more embodiments.

[0034] Figure 7B FIG. illustrates a top view of an expandable chamber structure of Figure 7A

[0035] Figure 8A FIG. illustrates a side view of an example anchor structure including a conduit structure in an attached configuration and can be implemented in one or more embodiments.

[0036] Figure 8B FIG. illustrates a cross-sectional view of an anchor structure of Figure 8A

[0037] Figure 9A FIG. illustrates a side view of an example conduit structure having a generally cylindrical form and can be implemented in one or more embodiments.

[0038] Figure 9B FIG. illustrates a cross-sectional view of a conduit structure of Figure 9A

[0039] Figure 10A FIG. illustrates a side view of an example conduit structure having a generally hourglass shape and can be implemented in one or more embodiments.

[0040] Figure 10B FIG. illustrates a cross-sectional view of a conduit structure of Figure 10A

[0041] Figure 11A FIG. illustrates a perspective view of an example conduit component including a fluid control device and can be implemented in one or more embodiments.

[0042] Figure 11B FIG. illustrates a top view of a conduit component of Figure 11A

[0043] FIG. illustrates a side view of a conduit component of Figure 11C Figure 11A FIG. illustrates a perspective view of an example valve structure having a generally cylindrical form and can be implemented in one or more embodiments.

[0044] Figure 12A FIG. illustrates a cross-sectional view of a valve structure of

[0045] Figure 12B Figure 12A ​​​​​​top view of a valve structure.

[0046] Figure 12C illustrates a side view of an example conduit structure implemented with a wireframe structure, in accordance with one or more embodiments. Figure 10A side view of a valve structure.

[0047] Figure 10B illustrates example inflatable chamber structures that connect at a conduit structure and can be implemented in one or more embodiments.

[0048] Figure 12A illustrates example inflatable chamber structures that include spring elements and can be implemented in one or more embodiments.

[0049] Figure 13 illustrates a side view of an example conduit structure implemented with a wireframe structure, in accordance with one or more embodiments.

[0050] Figure 14 illustrates a side view of another example conduit structure implemented with a wireframe structure, in accordance with one or more embodiments.

[0051] Figure 15-1 illustrates a side view of a valve structure implemented with a wireframe structure, in accordance with one or more embodiments.

[0052] Figure 15-2 illustrates a side view of an example inflatable chamber structure implemented with a wireframe structure, in accordance with one or more embodiments.

[0053] Figure 15-3 illustrates insertion of a guidewire during an example procedure for implanting a device in a patient, in accordance with one or more embodiments.

[0054] Figure 15-4 illustrates introduction of an inflatable chamber structure in a fluid vessel during an example procedure for implanting a device in a patient, in accordance with one or more embodiments.

[0055] Figure 16-1 illustrates deployment of an inflatable chamber structure during an example procedure for implanting a device in a patient, in accordance with one or more embodiments.

[0056] Figure 16-2 illustrates introduction of another inflatable chamber structure in another fluid vessel during an example procedure for implanting a device in a patient, in accordance with one or more embodiments.

[0057] Figure 16-3 illustrates deployment of another inflatable structure during an example procedure for implanting a device in a patient, in accordance with one or more embodiments.

[0058] Figure 16-4 FIG. 1 illustrates an example process for implanting a blood vessel pump within one or more blood vessels of a patient, in accordance with one or more embodiments of the present disclosure. DETAILED DESCRIPTION

[0059] The headings provided herein are for convenience only and do not necessarily affect the scope or meaning of the claimed inventive subject matter. The present disclosure relates to systems, devices, and methods for facilitating increased fluid flow through the use of inflatable chamber structures implantable in blood vessels of the human anatomy.

[0060] While certain preferred embodiments and examples are disclosed herein, the inventive subject matter extends beyond the specifically disclosed embodiments to other alternative embodiments and / or uses of the inventive subject matter and obvious modifications and equivalents thereof. It is therefore intended that the scope of the claims appended hereto be broad enough to cover all of the potentially relevant alternatives and modifications. For example, the acts or operations of any of the methods disclosed herein can be performed in any suitable order and need not be limited to any particular sequence or order. Various operations can be described as sequential processes, although many of the operations can be performed in parallel, concurrently, or in any suitable order. In addition, the descriptions and examples are not provided to limit the inventive subject matter to the specific embodiments or examples described or suggested. Various modifications and changes can be made thereto by those of ordinary skill in the art having the benefit of this disclosure without departing from the spirit of the inventive subject matter. For example, various aspects and advantages of the inventive subject matter can be used in conjunction, and / or in place of, aspects and advantages of other inventive subject matter disclosed herein. Thus, the scope of the inventive subject matter is not intended to be limited to the particular embodiments and examples described herein. Rather, the scope of the inventive subject matter is intended to cover all such modifications and variations as come within the scope of the appended claims and their equivalents.

[0061] The term“associated” is used herein in accordance with its broad and ordinary meaning. For example, when a first feature, element, component, device, or member is described as being“associated” with a second feature, element, component, device, or member, such description should be understood to indicate that the first feature, element, component, device, or member is directly or indirectly physically coupled, attached or connected, integrated, at least partially embedded within, or otherwise physically related to the second feature, element, component, device, or member.

[0062] As described above, congestive heart failure (CHF) is a condition in which the heart is unable to adequately pump blood to other organs of the body. In some cases, the right side of the heart can be unable to generate sufficient suction to draw blood from the renal veins into the vena cava and return the blood to the heart through the vena cava. Because the renal veins are connected to and receive filtered blood from the kidneys, a reduction in blood flow in the renal veins can have a negative impact on the function of the kidneys. For example, the heart can be unable to return a sufficient amount of filtered blood from the kidneys to the heart, thereby impacting kidney function. In addition, CHF can cause shortness of breath, exercise intolerance, fatigue, elevated venous pressure, edema, or hospitalization.

[0063] In some embodiments, the present disclosure relates to a device having a plurality of chambers that operate in an interactive manner to pump fluid in a blood vessel. For example, the device can include a first inflatable chamber structure implantable within a first fluid vessel (e.g., an abdominal aorta), and a second inflatable chamber structure implantable within a second fluid vessel (e.g., a vena cava proximate to a renal vein). The first inflatable chamber structure can be in fluid communication with the second inflatable chamber structure such that the first inflatable chamber structure and the second inflatable chamber structure expand and contract in opposite manners. For example, an increase in fluid pressure in the first fluid vessel can cause compression of the first inflatable chamber structure, which in turn causes expansion of the second inflatable chamber structure. Further, a decrease in fluid pressure in the first fluid vessel can cause expansion of the first inflatable chamber structure, which in turn causes contraction of the second inflatable chamber structure. This operation can pump fluid in the first vessel and / or the second vessel, such as blood to and from the heart.

[0064] Figure 16-5 An example human anatomy 100 having various features relevant to certain aspects of the present disclosure is illustrated. The human anatomy 100 includes a heart 110 fluidly coupled with an inferior vena cava 120 and an aorta 130. In particular, the heart 110 can pump blood through the aorta 130 to various portions of the human anatomy 100, and return blood to the heart 110 through the inferior vena cava 120. For example, blood can be pumped down the aorta 130 to arteries 135 attached to the aorta 130, such as the superior mesenteric artery, the left renal artery, and the right renal artery. Further, blood can be drawn from the renal veins 125 (i.e., the right and left renal veins) down the inferior vena cava 120 and back to the heart 110. As shown, the inferior vena cava 120 is adjacent to the aorta 130. The inferior vena cava 120 and the aorta 130 represent fluid vessels. It should be appreciated that, Figure 17 Certain of the various vessels, organs, and / or chambers shown in FIG. 1 are not necessarily drawn to scale and can be represented in relatively exaggerated form in order to clearly illustrate features and / or concepts that can be relevant to various aspects of the present disclosure. Fluid vessels can include any anatomical structure capable of carrying fluid, such as arteries, veins, capillaries, etc. Although certain embodiments are disclosed herein with respect to vessels (e.g., vessels of one or more aortic and / or venous systems), it should be appreciated that any of the disclosed devices can be implanted at least partially within any vessel, organ, and / or chamber of a patient’s anatomy, including within any chamber or vessel associated with the heart and / or the heart circulatory system.

[0065] In some embodiments, device 140 (sometimes referred to herein as "vascular pump 140") can be implanted within inferior vena cava 120 and / or aorta 130 to pump blood within inferior vena cava 120 and / or aorta 130. For example, device 140 can include a first inflatable chamber structure 170 implanted within aorta 130 proximate artery 135 (e.g., within the abdominal aorta and within a distance from artery 135) and an anchor structure 150 implanted within inferior vena cava 120 proximate renal vein 125. Anchor structure 150 can include a second inflatable chamber structure in fluid communication with first inflatable chamber structure 170, for example through a conduit or other structure implanted within the walls of inferior vena cava 120 and aorta 130. As used herein, the term "fluid" can refer to a gas, a liquid, or a combination. For example, the chamber structures disclosed herein can be inflated using any type of fluid, including saline or other liquid or gas. Although illustrated as implanted proximate renal vein 125, device 140 can be implanted at other locations within human anatomy 100, for example at other locations within inferior vena cava 120 or aorta 130, other fluid vessels, etc.

[0066] In operation, the first inflatable chamber structure 170 within the aorta 130 and the anchor structure 150 within the inferior vena cava 120 can operate in a cooperative manner to pump blood. For example, during systole (e.g., the heart 110 pumps blood to the body), the first inflatable chamber structure 170 can constrict due to the elevated blood pressure in the aorta 130, which in turn causes the second inflatable chamber structure of the anchor structure 150 to expand. Further, during diastole (e.g., the heart 110 fills with blood), the first inflatable chamber structure 170 can expand due to the reduced blood pressure in the aorta 130, which in turn causes the second inflatable chamber structure of the anchor structure 150 to constrict. This can create a suction and draw blood from the renal veins 125 into the inferior vena cava 120 to return to the heart 110. Thus, the device 140 can actively draw blood from the renal veins 125 through the natural pulsations of the abdominal aorta. In many embodiments, the device 140 does not include a power source (e.g., a battery or other power source), but rather operates based on the pressure / compression in the aorta 130, the inferior vena cava 120, or surrounding anatomy. Thus, the device 140 can improve kidney function and / or reduce end diastolic volume from the venous system. The reduced pressure in the inferior vena cava 120 and the renal veins 125 can improve kidney function and / or reduce the recurrence of systemic edema. In some embodiments, the device 140 can improve kidney function (e.g., improve the ability of the kidneys to pump deoxygenated blood to the inferior vena cava 120). As kidney function and heart function are interrelated, this can reduce the pressure in the inferior vena cava 120. The device 140 can also increase the compliance of the atrial system to reduce hypertension and / or improve atrial diastolic pressure.

[0067] The device 140 can be implemented as an intervascular fluid pump. A device can be considered intervascular when at least a component of the fluid pump is disposed / implanted within a portion of a continuous and / or contiguous portion of each of a plurality of blood vessels or a single blood vessel. Although many examples are discussed herein in the context of the first inflatable chamber structure 170 in the aorta 130 causing blood to be pumped within the inferior vena cava 120, the device 140 can operate in other manners, such as the anchor structure 150 in the inferior vena cava 120 causing blood to be pumped within the aorta 130. In some implementations, a plurality of inflatable chamber structures are implanted in the aortic system or the venous system (but not both) and create increased blood flow in the aortic system or the venous system (but not both).

[0068] Figure 1An example device 240 for pumping fluid is illustrated that includes a first inflatable chamber structure 270 and an anchor structure 250 in accordance with one or more embodiments of the present disclosure. The device 240 includes the first inflatable chamber structure 270, the anchor structure 250, and a conduit structure 260 for connecting the first inflatable chamber structure 270 and the anchor structure 250 with fluid. The first inflatable chamber structure 270 can be implanted within a first fluid vessel, such as the aorta 130, and the anchor structure 250 can be implanted within a second fluid vessel, such as the inferior vena cava 120. The anchor structure 250 can include a second inflatable chamber structure that is connected to the first inflatable chamber structure 270 by the conduit structure 260. In some embodiments, the conduit structure 260 can be rigid or semi-rigid to prevent inflation of the conduit structure 260. This can avoid inflation and damage to the walls of the fluid vessels in which the conduit structure 260 is implanted, such as the walls of the aorta or inferior vena cava. However, the conduit structure 260 can be formed of any material, whether rigid or flexible. Figure 1 Figure 2

[0069] While the device 240 is discussed as having two inflatable chamber structures, any number of inflatable chamber structures can be implemented. For example, a first inflatable chamber structure can be implemented within a first fluid vessel, a second inflatable chamber structure can be implemented within a second fluid vessel, and a third inflatable chamber structure can be implemented within a third fluid vessel. Here, inflation and deflation of the first inflatable chamber structure can cause the second and third inflatable chamber structures to contract and inflate in a unified manner, thereby simultaneously pumping fluid within the second and third fluid vessels.

[0070] Figure 1 ​​FIG. 1 illustrates a cross-sectional view of an aorta 130 and inferior vena cava 120 in which an example intervascular fluid pump device / assembly 140 is implanted to pump blood and / or increase blood flow within one or more of the illustrated vessels and / or portions thereof, in accordance with one or more embodiments of the present disclosure. As shown, the device 140 includes a first at least partially inflatable chamber structure 170 connected to an anchor structure 150 by a conduit structure 160. The anchor structure 150 is implanted within the inferior vena cava 120 and is associated with a second inflatable chamber structure 155. The first inflatable chamber structure 170 is advantageously in fluid communication with the second inflatable chamber structure 155 by the conduit structure 160, which extends through a wall of the aorta 130 and a wall of the inferior vena cava 120. As used herein, the term "inflatable chamber structure" can generally refer to a structure and a cavity within the structure. For example, a chamber structure can include one or more walls that form an at least partially fluid-tight cavity. Further, the term "conduit structure" can generally refer to a structure and a cavity within the structure. For example, a conduit structure can include a balloon, a tube, a hose, or other structure in which a lumen is formed to enable fluid to pass through and / or be contained therein.

[0071] The anchor structure 150 also includes a first conduit structure 151, a second conduit structure 152, and a valve structure 156. The first conduit structure 151 can have a generally hourglass shape and a lumen extending longitudinally through a center of the first conduit structure 151. As shown, the first conduit structure 151 can also include a fluid control device 153 to allow or prevent fluid flow from an intake cavity 157. The fluid control device 153 can include a one-way valve that allows fluid flow in one direction, an orifice, or other structure. The second conduit structure 152 can have a generally cylindrical shape and one or more apertures 154 extending radially. The second conduit structure 152 can be configured to contain at least a portion of the first conduit structure 151. The valve structure 156 is configured to be longitudinally aligned with the first conduit structure 151 and can be disposed between the second inflatable chamber structure 155 and the second conduit structure 152. The valve structure 156 can be configured to shift in a radial direction (e.g., toward the second conduit structure 152) to prevent fluid flow through the apertures 154 of the second conduit structure 152, as discussed in further detail below. Although the first conduit structure 151, the second conduit structure 152, and the valve structure 156 are illustrated as having various cross-sectional shapes, such components can include other forms, such as hyper-rectangular forms, elliptical forms, etc. Further, while many embodiments are illustrated as having a single inflatable chamber structure in the first inflatable chamber structure 170 and a single inflatable chamber structure in the anchor structure 150, any number of inflatable chamber structures can be implemented.

[0072] As shown in the figure, the components of the anchor structure 350 are configured to form a suction cavity 357. Specifically, a second conduit structure 352 is disposed around the first conduit structure 351, such that a gap exists between the first conduit structure 351 and the second conduit structure 352. A second expandable chamber structure 355 is disposed between the first conduit structure 351 and the second conduit structure 352 and expands to fill the cavity. Figure 1 At least a portion of the suction cavity 357 shown. Figure 3 As shown, the second expandable chamber structure 355 can be located at the bottom of the first conduit structure 351, for example, on a portion of the first conduit structure 351 where the diameter increases. A valve structure 356 is disposed between the second expandable chamber structure 355 and the second conduit structure 352. In this configuration, the components create an intake cavity 357 that extends circumferentially around the first conduit structure 351.

[0073] In some embodiments, when in such a situation Figure 3 In the illustrated implantation state, the upper portion (having a larger diameter) of the first conduit structure 351 contacts or is positioned near the inner surface of the inferior vena cava 320, and the lower portion (having a larger diameter) of the first conduit structure 351 contacts or is positioned near the inner surface of the inferior vena cava 320. The upper portion of the first conduit structure 351 may be positioned above the renal vein 325, and the lower portion of the first conduit structure 351 may be positioned below the renal vein 325. This results in the central portion (having a smaller diameter) of the first conduit structure 351 being positioned near the renal vein 325. In some embodiments, one or more anchors are attached to the inferior vena cava 320 (above and / or below the anchor structure 350) and to the anchor structure 350 to hold the anchor structure 350 in a substantially fixed position. Similarly, one or more anchors are attached to the aorta 330 (above and / or below the first expandable chamber structure 370) and to the first expandable chamber structure 370 to hold the first expandable chamber structure 370 in a substantially fixed position.

[0074] Although Figure 3Although not shown, in some embodiments, the device 340 can include a port for connection to a control device configured to control one or more characteristics of the device 340. For example, the first inflatable chamber structure 370 and / or the second inflatable chamber structure 355 can be connected to a control device (which can include processing circuitry and / or memory) located outside the human body, e.g., on or within a layer of skin. The control device can adjust the pressure or fluid in the first inflatable chamber structure 370 and / or the second inflatable chamber structure 355, e.g., the amount of fluid within the inflatable chamber structures 370 and 355. By doing so, the control device can adjust the amount of blood flow that the device 340 is able to pump, the pressure required to initiate blood pumping, or various other characteristics of the device 340. In some embodiments, the control device can enable the fluid within the first inflatable chamber structure 370 and / or the second inflatable chamber structure 355 to be replaced. In some cases, the control device can include an external injection port to facilitate such replacement.

[0075] Figure 3 FIG. 1 illustrates components of an example device configured to pump fluid, in accordance with one or more embodiments of the present disclosure.

[0076] Figure 3 An example upper portion 451 A of the first conduit structure 451 is illustrated. The upper portion 451 A can include a fluid control device 453, e.g., a one-way valve, a hole, or other structure. An end 461 of the upper portion 451 A can be configured to connect to Figures 4-1 to 4-6 An example lower portion 451 B of the first conduit structure 451 is illustrated. The upper portion 451 A can be connected to the lower portion 451 B in a variety of ways, e.g., by threading, adhesive, or other attachment mechanism. Accordingly, the upper portion 451 A and / or the lower portion 451 B can include threading or other attachment mechanism.

[0077] Figure 4-1 An example lower portion 451 B of the first conduit structure 451 is illustrated. An end 463 of the lower portion 451 B can be configured to connect to the upper portion 451 A of the first conduit structure 451 by a variety of mechanisms, as described above. Although the upper portion 451 A and the lower portion 451 B are illustrated as separate components, in some embodiments, the upper portion 451 A and the lower portion 451 B form a single, unitary form or are connected at other locations.

[0078] Figure 4-2 An example second conduit structure 452 is illustrated, which is configured to be associated with the first conduit structure 451. As shown, the second conduit structure 452 has a generally cylindrical shape and includes holes 454 around the circumference of the second conduit structure 452. The holes 454 extend radially through the second conduit structure 452. Although a particular number of holes 454 is illustrated, any number of holes can be implemented.

[0079] Figure 4-2 An example second inflatable chamber structure 455 is illustrated, which is configured to be implemented with the first conduit structure 451 and the second conduit structure 452. Here, the second inflatable chamber structure 455 is shown in a generally deflated state. In the deflated state, the second inflatable chamber structure 455 can include a generally cylindrical form with a lip 462 extending radially from the body of the second inflatable chamber structure 455.

[0080] Figure 4-3 An example valve structure 456 is illustrated, which is configured to be implemented with the first conduit structure 451, the second conduit structure 452, and the second inflatable chamber structure 455 to block or allow fluid flow through the aperture 454. The valve structure 456 can include a generally cylindrical form and a lip 464 extending radially from the body of the valve structure 456. In some embodiments, the valve structure 456 can have a diameter that is greater than the diameter of the second inflatable chamber structure 455 in the deflated state. This can allow the valve structure 456 to be disposed around the second inflatable chamber structure 455.

[0081] Figure 4-4 An example first inflatable chamber structure 470 is illustrated, which is configured to be implemented with the second inflatable chamber structure 455. The first inflatable chamber structure 470 can include a generally cylindrical form, as illustrated. The first inflatable chamber structure 470 can include a structure that encloses fluid. The first inflatable chamber structure 470 can include a first end 465 and a second end 466. Although not illustrated, the first inflatable chamber structure 470 can be connected to the second inflatable chamber structure 455 by a conduit or other mechanism. Further, in some embodiments, the first inflatable chamber structure 470 and the second inflatable chamber structure 455 form a unitary form.

[0082] While the upper portion 451 A, the lower portion 451 B, the second conduit structure 452, the second inflatable chamber structure 455, the valve structure 456, and the first inflatable chamber structure 470 are illustrated in a generally cylindrical form, these components can include a variety of forms (e.g., in the inflated / deflated state). For example, any of these components can be implemented in a super-rectangular form, an elliptical form, or other form.

[0083] Figure 4-5 Aspects of an example diastolic phase of a cardiac cycle of a device 540 configured to pump fluid are illustrated in accordance with one or more embodiments of the present disclosure. Figure 4-6 And Figures 5-1 to 5-3 Aspects of an example diastolic phase of a cardiac cycle of a device 540 configured to pump fluid are illustrated in accordance with one or more embodiments of the present disclosure. Figure 5-1The graph 580 shows the aortic pressure in mmHg versus time in seconds. Point 582 on graph 580 shows the time when the aortic pressure is at its minimum.

[0084] like Figure 5-2 and Figure 5-3 As shown, the device 540 includes a first expandable chamber structure 570 and a second expandable chamber structure 555, the second expandable chamber structure 555 being in fluid communication with the first expandable chamber structure 570 via a pipe structure 560. Figure 5-1 As shown, when implanted, a first expandable chamber structure 570 is located within the aorta 530, and a second expandable chamber structure 555 is located within the inferior vena cava 520, wherein a conduit structure 560 extends through the walls of the aorta 530 and the inferior vena cava 520. The device 540 also includes a first conduit structure 551, a second conduit structure 552, a valve structure 556, and an aspiration cavity 557 between the first conduit structure 551 and the second conduit structure 552. In some embodiments, when implanted, the upper portion (having a larger diameter) of the first conduit structure 551 contacts or is placed near the inner surface of the inferior vena cava 520, the central portion (having a smaller diameter) of the first conduit structure 551 is located around the renal vein 525, and the lower portion (having a larger diameter) of the first conduit structure 551 contacts or is placed near the inner surface of the inferior vena cava 520. In this position, the device 540 can be sealed against the inner surface of the inferior vena cava 520 to form an aspiration zone around the renal vein 525, which facilitates the aspiration of blood from the renal vein 525, as described below. This aspiration zone can be at least partially created by the hourglass shape of the device 540.

[0085] In some embodiments, the device 540 may operate based on changes in aortic blood pressure (e.g., an increase or decrease in pressure within the aorta 530). For example, during diastole, aortic blood pressure decreases (e.g., during diastole). Figure 5-2 (As shown) and the heart (not shown) is refilled with blood by drawing blood through the inferior vena cava 520 and other vessels. As the aortic blood pressure decreases, the first expandable chamber structure 570 expands, causing the second expandable chamber structure 555 to contract and the valve structure 556 to shift radially inward away from the orifice 554 in the second conduit structure 552 (e.g., opening the orifice 554 for fluid flow). This creates suction in the suction cavity 557, which causes the fluid control device 553 in the first conduit structure 551 (which may be implemented as a one-way valve) to close and prevent blood from the inferior vena cava 520 from flowing down into the suction cavity 557. This suction also draws blood from the renal vein 525 through the orifice 554 and into the suction cavity 557. Figure 5-2 and Figure 5-3Figures illustrate aspects of an example systolic phase of a cardiac cycle of a device 640 configured to pump fluid, in accordance with one or more embodiments of the present disclosure. Figure 5-1 As shown, during diastole, blood can also flow through the inferior vena cava 520 in a normal manner by flowing through an interior portion of the device 540 (e.g., through a central lumen of the first conduit structure 551). Figure 5-2 The dark arrows in show blood flow during diastole (e.g., blood flow from the renal vein 525 into the suction cavity 557 and blood flow through a central lumen in the first conduit structure 551).

[0086] In some embodiments, blood collected into the suction cavity 557 from the renal vein 525 during diastole is pumped out of the suction cavity 557 (through the fluid control device 553 in the first conduit structure 551) during systole, as described below. However, in some embodiments, blood collected in the suction cavity 557 can be at least partially pumped out of the suction cavity 557 (through the fluid control device 553) during diastole.

[0087] Figure 5-2 Figures illustrate aspects of an example systolic phase of a cardiac cycle of a device 640 configured to pump fluid, in accordance with one or more embodiments of the present disclosure. Figure 5-2 and Figures 6-1 to 6-3 Figures illustrate aspects of an example systolic phase of a cardiac cycle of a device 640 configured to pump fluid, in accordance with one or more embodiments of the present disclosure. Figure 6-1 Figures illustrate aspects of an example systolic phase of a cardiac cycle of a device 640 configured to pump fluid, in accordance with one or more embodiments of the present disclosure.

[0088] As shown, the device 640 includes a first inflatable chamber structure 670 and a second inflatable chamber structure 655, which is in fluid communication with the first inflatable chamber structure 670 through a conduit structure 660. As shown, Figure 6-2 and Figure 6-3 As shown, the device 640 includes a first inflatable chamber structure 670 and a second inflatable chamber structure 655, which is in fluid communication with the first inflatable chamber structure 670 through a conduit structure 660. As shown, Figure 6-1As shown, when implanted, the first inflatable chamber structure 670 is located in the aorta 630 and the second inflatable chamber structure 655 is located within the inferior vena cava 620, with the conduit structure 660 extending through the walls of the aorta 630 and the inferior vena cava 620. The device 640 also includes a first conduit structure 651, a second conduit structure 652, a valve structure 656, and a suction cavity 657 between the first conduit structure 651 and the second conduit structure 652. In some embodiments, when in the implanted state, an upper portion of the first conduit structure 651 (having a larger diameter) contacts or is placed near an inner surface of the inferior vena cava 620, a central portion of the first conduit structure 651 (having a smaller diameter) is located around the renal vein 625, and a lower portion of the first conduit structure 651 (having a larger diameter) contacts or is placed near an inner surface of the inferior vena cava 620. In such a position, the device 640 can create a suction zone around the renal vein 625 to draw blood from the renal vein 625, as discussed above with reference to FIGS. 1-3. Figure 6-2

[0089] In some embodiments, the device 640 can operate based on changes in aortic blood pressure (e.g., an increase or decrease in pressure in the aorta 630). For example, during systole, aortic blood pressure increases (as shown in FIG. 6A), and the heart (not shown) pumps blood through the aorta 630 and other blood vessels. As the aortic blood pressure increases, the first inflatable chamber structure 670 constricts (e.g., is compressed), causing the second inflatable chamber structure 655 to radially expand and the valve structure 656 to radially shift outward to occlude the hole 654 in the second conduit structure 652. Thus, the valve structure 655 can prevent blood from flowing from the renal vein 625 into the suction cavity 657. In addition, as the second inflatable chamber structure 655 expands, the pressure in the suction cavity 652 increases, causing the fluid control device 653 to open and blood in the suction cavity 657 to be pushed out of the suction cavity 657 through the fluid control device 653. In some embodiments, the fluid control device 653 is implemented as a one-way valve that allows blood to flow from the suction cavity 657 into the inferior vena cava 620 (e.g., when the pressure is higher than the amount in the suction cavity 657) and prevents blood from flowing from the inferior vena cava 620 into the suction cavity 657. Figure 6-2 Figures 5-1 to 5-3 and Figure 6-3 FIG. 6A illustrates a state of the device 640 during systole when the first inflatable chamber structure 670 constricts and the second inflatable chamber structure 655 expands (e.g., when the aortic pressure is at or near a maximum). Figure 6-1 The dark arrows in FIG. 6A show blood flow during systole (e.g., from the suction cavity 657 into the inner portion of the first conduit structure 651 and the inferior vena cava 620).

[0090] While in the implanted state, the device 640 can operate based on changes in aortic blood pressure (e.g., an increase or decrease in pressure in the aorta 630). For example, during diastole, aortic blood pressure decreases (as shown in FIG. 6B), and the heart (not shown) pumps blood through the aorta 630 and other blood vessels. As the aortic blood pressure decreases, the first inflatable chamber structure 670 expands, causing the second inflatable chamber structure 655 to constrict and the valve structure 656 to shift inward to open the hole 654 in the second conduit structure 652. Thus, the valve structure 655 can allow blood to flow from the renal vein 625 into the suction cavity 657. In addition, as the first inflatable chamber structure 670 expands, the pressure in the suction cavity 657 decreases, causing the fluid control device 653 to close and blood in the suction cavity 657 to be drawn into the suction cavity 657 through the fluid control device 653. In some embodiments, the fluid control device 653 is implemented as a one-way valve that allows blood to flow from the inferior vena cava 620 into the suction cavity 657 (e.g., when the pressure is lower than the amount in the suction cavity 657) and prevents blood from flowing from the suction cavity 657 into the inferior vena cava 620. Figure 6-2 and​​Figure 6-2 The valve structure is illustrated, but in some embodiments the valve structure is not implemented and the expandable chamber structure is used to allow or block fluid flow into the suction cavity. For example, the device 640 can be implemented without the valve structure 656. Here, the second expandable chamber structure 655 can expand and contract to block and open the hole 654 (e.g., to block or allow blood flow into the suction cavity 657).

[0091] Figure 5-2 An example expandable chamber structure that can be implemented in one or more embodiments of the present disclosure is illustrated. Specifically, Figure 6-2 A side view of a first expandable chamber structure 770 connected to a second expandable chamber structure 755 by a conduit structure 760 is shown. Figures 7A-7B A top view of the first expandable chamber structure 770 and the second expandable chamber structure 755 is shown. Figure 7A The conduit structure 760 is shown in Figure 7B and Figure 7A In some embodiments, the conduit structure 760 is not implemented and the first expandable chamber structure 770 is directly connected to the second expandable chamber structure 755.

[0092] The second expandable chamber structure 755 can include an inner surface 780 that is generally cylindrical in shape. The diameter of the inner surface 780 can be designed to the diameter of the conduit structure over which the second expandable chamber structure 755 can be placed. In some embodiments in which the conduit structure has an hourglass shape, a lower portion 782 of the inner surface 780 can extend radially outward to sit on a lower portion of the conduit structure, which can have a slightly larger diameter. In some embodiments, the second expandable chamber structure 755 has a tapered cylindrical shape. For example, an outer surface of an upper portion of the second expandable chamber structure 755 can have a smaller diameter than an outer surface of a middle or lower portion of the second expandable chamber structure 755 when in an expanded or contracted state.

[0093] The first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 can be filled with a fluid. For example, the first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 can form a closed system filled with saline, air, etc. In some embodiments, the first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 are filled to a particular pressure (e.g., pressurized). The first inflatable chamber structure 770 and the second inflatable chamber structure 755 can generally freely exchange fluid based on the pressure exerted on the first inflatable chamber structure 770 or the second inflatable chamber structure 755. For example, if pressure is exerted on the outer surface of the first inflatable chamber structure 770, this can cause the fluid in the first inflatable chamber structure 770 to be transferred to the second inflatable chamber structure 755. In some embodiments, the first inflatable chamber structure 770 (and / or the second inflatable chamber structure 755) can be associated with blood flow hemodynamic properties similar to an intra-aortic balloon pump (IABP).

[0094] The first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 can be formed from structures and / or materials that are configured to inflate or deflate. In some embodiments, the first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 can be formed from a flexible mesh or wire frame structure that generally maintains a particular form unless sufficient force is applied. The mesh or wire frame structure can be formed from metal, plastic, or other materials, and / or can include materials disposed therein, such as silicone, plastic, etc. Further, in some embodiments, the first inflatable chamber structure 770 and / or the second inflatable chamber structure 755 (or the conduit structure 760) can be implemented as a compliant or semi-compliant balloon. As described herein, the term "compliant" or "compliance" can refer to the ability of an article to expand and increase in volume with an increase in pressure, or the tendency of an article to resist recoil toward its original size when a distending or compressive force is applied. For example, the compliance of an inflatable chamber structure can refer to the ability of the inflatable chamber structure to stretch in response to an applied pressure. In some embodiments, an inflatable chamber structure can have more or less compliance as compared to another inflatable chamber structure. For example, the first inflatable chamber structure 770 and the second inflatable chamber structure 755 can each be implemented as a balloon, with the second inflatable chamber structure 755 being more compliant (e.g., having greater stretch) than the first inflatable chamber structure 770. However, in other examples, the compliance of the first inflatable chamber structure 770 and the compliance of the second inflatable chamber structure 755 can be switched. In yet other embodiments, the first inflatable chamber structure 770 and / or the second inflatable chamber structure 755 (or the conduit structure 760) can be implemented as a non-compliant balloon. Thus, the first inflatable chamber structure 770 and / or the second inflatable chamber structure 755 (or the conduit structure 760) can have particular compliance characteristics. The first inflatable chamber structure 770, the second inflatable chamber structure 755, and / or the conduit structure 760 can be formed from a variety of materials, such as polyurethane, silicone, metal, plastic, etc.

[0095] In some embodiments, the first inflatable chamber structure 770 and / or the second inflatable chamber structure 755 can be designed to inflate and / or deflate within a particular pressure range. For example, the first inflatable chamber structure 770 can be configured to deflate when pressure (within a range of aortic pressures associated with a systolic phase of a cardiac cycle) is applied to the first inflatable chamber structure 770, and can be configured to inflate when pressure (within a range of aortic pressures associated with a diastolic phase of a cardiac cycle) is applied to the first inflatable chamber structure 770. Alternatively or additionally, the second inflatable chamber structure 755 can be configured to inflate in response to pressure applied within a particular range and to deflate in response to pressure applied within another range.

[0096] Figure 7A An example anchor structure 850 is illustrated, which includes a pipe structure in an attached configuration and can be implemented in one or more embodiments of the present disclosure. Specifically, Figure 7B A side view of the anchor structure 850 is shown, while Figures 8A-8B A cross-sectional view of the anchor structure 850 is shown. Here, the anchor structure 850 includes a first pipe structure 851 attached to a second pipe structure 852. For example, the second pipe structure 852 is disposed around a central portion of the first pipe structure 851. Although discussed as separate components in many embodiments, the first pipe structure 851 and the second pipe structure 852 can be a single unitary component. The first pipe structure 851 can include a fluid control device 853 disposed in an upper portion of the first pipe structure 851, for example, in a portion between a minimum diameter of the first pipe structure 851 and a maximum diameter of the first pipe structure 851. Although the fluid control device 853 is shown at an upper position in Figure 8A , the fluid control device 853 can be located at other positions, for example, in a central portion 880 of the first pipe structure 851 or in a lower portion of the first pipe structure 851. The second pipe structure 852 can include holes 854 disposed in a central portion of the second pipe structure 852. Although holes are discussed, in some embodiments, the holes 854 can be replaced with one-way flaps or other structures. The first pipe structure 851 and the second pipe structure 852 can be attached to produce a cavity 857. In some embodiments, the second pipe structure 852 can contact the first pipe structure 851 at an upper portion and a lower portion of the first pipe structure 851, such that fluid can only enter or exit the cavity 857 through the fluid control device 853 and the holes 854. Although a particular number of holes 854 and fluid control devices 853 are shown in Figure 8B and Figure 8B , any number of holes and / or fluid control devices 853 can be implemented.

[0097] Figure 8A An example pipe structure 952 is illustrated, which has a generally cylindrical form and can be implemented in one or more embodiments of the present disclosure. Specifically, Figure 8B A side view of the pipe structure 952 is shown, while Figures 9A-9B A cross-sectional view of the pipe structure 952 is shown. The pipe structure 952 can include holes 954 disposed circumferentially around the pipe structure 952. In some embodiments, for example, Figure 9A and Figure 9BIn the illustrated embodiment, the holes 954 are disposed about a central portion of the conduit structure 952. In other embodiments, the holes 954 can be disposed at other locations on the conduit structure 952. The conduit structure 952 can comprise a cylinder, where the wall of the cylinder has a particular thickness. However, in other embodiments, the conduit structure 952 can have other forms, such as a super-rectangular form or any other form. In some embodiments, the conduit structure 952 can be configured to have a rigid or semi-rigid structure.

[0098] Figure 9A An example conduit structure 1051 is illustrated, which has a generally hourglass shape and can be implemented in one or more embodiments of the present disclosure. Specifically, Figure 9B A side view of the conduit structure 1051 is shown, Figures 10A-10B A cross-sectional view of the conduit structure 1051 is shown. The conduit structure 1051 can include an upper portion 1080, a central portion 1081, and a lower portion 1082. As shown, the diameter of the upper portion 1080 (in a direction toward the outer end of the upper portion 1080) increases from the diameter of the central portion 1081 to a maximum diameter of the upper portion 1080. Similarly, the diameter of the lower portion 1082 (in a direction toward the outer end of the lower portion 1082) decreases from the diameter of the central portion 1081 to a maximum diameter of the lower portion 1022. Both the maximum diameter of the upper portion 1080 and the maximum diameter of the lower portion 1082 can be greater than the diameter of the central portion 1081. Further, the diameter of the central portion 1081 can be less than the diameter of another conduit structure, such as Figure 10A and Figure 10B The conduit structure 952 of FIGS. 1-3, which is configured to be disposed about the conduit structure 1051. The upper portion 1080 can include a fluid control device 1053, such as a one-way valve, a hole, etc. The conduit structure 1051 can be formed as a single unitary component or various components. The walls of the conduit structure 1051 can have a variety of thicknesses. As shown, an interior portion of the conduit structure 1051 can include a lumen (e.g., an open passageway) that extends longitudinally through the conduit structure 1051 to allow fluid to flow axially through the conduit structure 1051 in either direction. In some embodiments, the conduit structure 1051 can be configured to have a rigid or semi-rigid structure when deployed.

[0099] Figure 9A An example conduit component 1180 is illustrated, which includes a fluid control device 1183 and can be implemented in one or more embodiments of the present disclosure. Specifically, Figure 9B A perspective view of the conduit component 1180 is shown, Figures 11A-11C A top view of the conduit component 1180 is shown, and Figure 11A A side view of the conduit component 1180 is shown. In some embodiments, the conduit component 1180 is implemented as part of an hourglass conduit structure, such as Figure 11B andFigure 11C The hourglass pipe structure 1051. For example, pipe component 1180 can be attached to... Figure 10A and Figure 10B The central part 1081 of the hourglass pipe structure 1051. For example... Figure 10A As shown, the pipe component 1180 includes a fluid control device 1153, which is circumferentially disposed in the diameter-changing portion 1085 of the pipe component 1180. The fluid control device 1153 may include a one-way valve, an orifice, or other device. For ease of illustration, Figure 10B and Figures 11A-11C (And in various other figures) the fluid control device 1153 is illustrated as an opening, while Figure 11A The fluid control device 1153 is illustrated as a one-way valve. The central portion 1190 of the conduit component 1180 is typically openable to allow fluid to flow axially through the conduit component 1180. However, in some embodiments, the central portion 1190 may include a one-way valve or other components.

[0100] Figure 11C An example valve structure 1256 is illustrated, which has a generally cylindrical shape and can be implemented in one or more embodiments of this disclosure. Specifically, Figure 11B A perspective view of valve structure 1256 is shown. Figures 12A-12C A top view of valve structure 1256 is shown, and Figure 12A A side view of valve structure 1256 is shown. In some embodiments, valve structure 1256 may be referred to as a renal vein valve because, when deployed, valve structure 1256 functions to control the flow of blood from the renal vein into the suction chamber of a device for pumping blood. As shown, valve structure 1256 may include a first portion 1280 and a second portion 1281. The second portion 1281 may extend radially such that the distal end of the second portion 1281 has a larger diameter than the first portion 1280 relative to the first portion 1280. The second portion 1281 may be configured to be located on the lower part of the conduit structure, for example... Figure 12B and Figure 12C The lower part 1082 of the conduit structure 1051. The valve structure 1256 can be formed of a flexible material such as plastic, silicone, or other materials, allowing the valve structure 1256 to expand (or shift) radially. Figure 10A In this embodiment, valve structure 1256 includes a tapered end portion 1283 (e.g., a portion with a reduced diameter). However, in other embodiments, valve structure 1256 may not include the tapered portion.

[0101] Figure 10BAn example inflatable chamber structure 1370 and 1355 that are connected by a conduit structure 1360 and can be implemented in one or more embodiments of the present disclosure are illustrated. Specifically, a first inflatable chamber structure 1370 is connected to a second inflatable chamber structure 1355 at a generally central portion of the second inflatable chamber structure 1355. Here, the length of the conduit structure 1360 is relatively short (e.g., less than the distance) to illustrate that the first inflatable chamber structure 1370 and the second inflatable chamber structure 1355 can be connected in a nearly direct manner without a passageway between the first inflatable chamber structure 1370 and the second inflatable chamber structure 1355. In some embodiments, the conduit structure 1360 can be removed entirely and the first inflatable chamber structure 1370 can be connected to the second inflatable chamber structure 1355 to form a nearly uniform inflatable chamber structure.

[0102] Figures 12A-12C An example inflatable chamber structure 1470 and 1455 that include spring elements 1481 and 1480, respectively, and can be implemented in one or more embodiments of the present disclosure are illustrated. The spring elements 1481 and 1480 can be disposed within the inflatable chamber structures 1470 and 1455, respectively. The spring elements 1481 and 1480 can be used as a chamber support structure that supports the inflatable chamber structures 1470 and 1455 (which can be implemented with a balloon), where the chamber support structure can be configured to exert an outward force on the inner surface of the inflatable chamber structure to resist collapse and / or assist in chamber expansion recoil. In some embodiments, the spring elements 1481 and / or 1480 can include a metal or plastic frame that is configured to hold a particular form unless sufficient force is applied to it. Although the first inflatable chamber structure 1470 and the second inflatable chamber structure 1455 are both illustrated as including spring elements, in some embodiments, only one of the inflatable chamber structures is associated with a spring element. Figure 13 In some embodiments, only one of the inflatable chamber structures is associated with a spring element.

[0103] Figure 14 An example of a device component implemented with a wireframe structure in accordance with one or more embodiments of the present disclosure is illustrated. Specifically, Figure 14 A side view of a second conduit structure 1552 that is configured to be associated with a first conduit structure 1551 is illustrated, Figures 15-1 to 15-4 A side view of a first conduit structure 1551 having a generally hourglass shape is illustrated, Figure 15-1 A side view of a valve structure 1556 is illustrated, and Figure 15-2A side view of expandable chamber structures 1570 and 1555 connected by a conduit structure 1560 is illustrated. In some embodiments, the wireframe structure comprises a partially rigid frame, which can comprise an expandable metal or plastic frame covered and / or filled by a sleeve or covering, such as silicone, plastic, or other flexible material. In some embodiments, the second conduit structure 1552, the first conduit structure 1551, the valve structure 1556, and / or the expandable chamber structures 1570 and 1555 (or any other component discussed herein) can be implemented as a stent (sometimes referred to as a “stent structure”), such as a stent similar to an esophageal stent. The stent can comprise a wireframe structure. In a compressed or collapsed configuration, the stent can be transported to a target implantation location using a catheter, as discussed below with reference to FIGS. 17A-17C. The stent can be expanded at the target implantation location, as discussed below with reference to FIGS. 17A-17C. Figure 15-3 Further discussed in detail below. In some embodiments, one or more components are attached or configured in a deployed state, as shown in the example of Figure 15-4 , the components are then compressed or collapsed and transported to a target implantation location. In other embodiments, the components can be individually compressed or collapsed and transported to a target implantation location.

[0104] Figures 16-1 to 16-5 An example procedure for implanting a device into a patient at a target implantation location is illustrated in accordance with one or more embodiments of the present disclosure. In some embodiments, a catheter-based procedure can be used to implant a device into a patient. For example, the implantation procedure can be similar to a trans-catheter aortic valve replacement (TAVR) or trans-catheter aortic valve implantation (TAVI) procedure using a trans-vena cava approach.

[0105] As shown in Figure 3 , a guidewire 1680 is introduced into the inferior vena cava 1620 and then into the aorta 1630 surrounding the renal vein 1625 and the artery 1635. That is, the guidewire 1680 travels up through the inferior vena cava 1620, through a wall of the inferior vena cava 1620 adjacent to a wall of the aorta 1630, and through a wall of the aorta 1630. As shown in Figures 16-1 to 16-5 , the inferior vena cava 1620 is generally adjacent to the aorta 1630 at a location where the guidewire 1680 passes from the inferior vena cava 1620 into the aorta 1630. In some embodiments, the guidewire 1680 enters the patient through a femoral vein. However, the guidewire 1680 can enter the patient at any location.

[0106] As shown in Figure 16-1 , a first expandable chamber structure 1670 can then be introduced into the aorta 1630 using the guidewire 1680 and / or a catheter (not shown). For example, the first expandable chamber structure 1670 can be implemented with a wireframe structure (e.g., a stent structure) that is compressed or collapsed to implant the first expandable chamber structure 1670 into the aorta 1630 near the renal vein 1625. Figure 16-1A first expandable chamber structure 1670 in a compressed or collapsed state is illustrated. As shown, once the first expandable chamber structure 1670 is positioned within the aorta 1630, the first expandable chamber structure 1670 expands to a deployed state (e.g., the stent structure of the first expandable chamber structure 1670 expands), such as a state in which the first expandable chamber structure 1670 functions to pump blood. Figure 16-2

[0107] As shown, the catheter can then be used with the guidewire 1680 to introduce the second expandable chamber structure 1650 into the inferior vena cava 1620. For example, the second expandable chamber structure 1650 can be implemented with a wireframe structure (e.g., a stent structure) that is compressed or collapsed to implant the second expandable chamber structure 1650 into the inferior vena cava 1620 at or near the renal veins 1625. Figure 16-2 Figure 16-3 A second expandable chamber structure 1650 in a compressed or collapsed state is illustrated. The second expandable chamber structure 1650 can be introduced into the inferior vena cava 1620 with other components (e.g., anchor structures and / or conduit structure(s)). In some embodiments, the second expandable chamber structure 1650 is implanted with a set of components, such as those shown in the example of FIG. 16, which are connected to one another in a configuration that will use the second expandable chamber structure 1650. Once connected in this configuration, the components are compressed or collapsed into a set and then implanted within the inferior vena cava 1620. Figure 16-4

[0108] Upon implantation at or near the renal veins 1625, the second expandable chamber structure 1650 expands to a deployed state, such as a state in which the second expandable chamber structure 1650 functions to pump blood. The second expandable chamber structure 1650 can be connected to the first expandable chamber structure 1670 via the conduit structure 1660 at different times, such as whenever the second expandable chamber structure 1650 is within a predetermined distance of the first expandable chamber structure 1670 in either a collapsed state or an expanded state. In some embodiments, the conduit structure 1660 is implanted with the first expandable chamber structure 1670 and / or the second expandable chamber structure 1650, or separately implanted within the wall of the inferior vena cava 1620 and the wall of the aorta 1630. Figure 16-4 A second expandable chamber structure 1650 and a first expandable chamber structure 1670 in a connected and deployed state are illustrated, in which the first expandable chamber structure 1670 and the second expandable chamber structure 1650 function to pump blood within the inferior vena cava 1620. For example, the first expandable chamber structure 1670 and the second expandable chamber structure 1650 can operate in coordination to draw blood from the renal veins 1625 and pump the blood up through the inferior vena cava 1620 back to the heart (not shown). ​​​

[0109] Figure 3 FIG. 17 illustrates an example process 1700 for implanting a blood vessel pump within one or more blood vessels of a patient, in accordance with one or more embodiments of the present disclosure. Process 1700 can be performed to increase diastolic pressure, which can include pressure in the right atrium, pressure in the left ventricle, pressure in the inferior vena cava (or any portion of the ventricular system, including one or more renal veins), or other pressure associated with the diastolic phase of the cardiac cycle (or any other phase of the cardiac cycle). In some embodiments, process 1700 can be performed to implant a blood vessel pump within a first fluid vessel, such as the aorta, and a second fluid vessel, such as the inferior vena cava. For ease of discussion, many of the embodiments discussed below can refer to the aorta and the inferior vena cava.

[0110] At 1702, a guidewire can be advanced through a wall of the second fluid vessel and / or a wall of the first fluid vessel. For example, a guidewire can be advanced through the inferior vena cava to a position within a distance of the renal veins in the inferior vena cava. In some embodiments, the guidewire can enter the patient through the femoral vein. However, the guidewire can enter the patient at any location and travel through the inferior vena cava (or another fluid vessel) to the target location for implantation.

[0111] At 1704, a first inflatable chamber structure can be deployed in the first fluid vessel of the patient. For example, a first inflatable chamber structure can be deployed in the aorta of the patient by advancing a delivery catheter through the inferior vena cava into the aorta using the guidewire and deploying the first inflatable chamber structure connected to the delivery catheter into the aorta.

[0112] At 1706, a second inflatable chamber structure can be deployed in the second fluid vessel of the patient. For example, a second inflatable chamber structure can be deployed in the inferior vena cava of the patient by advancing a delivery catheter or another delivery catheter through the inferior vena cava to the target location for implantation using the guidewire or another guidewire and deploying the second inflatable chamber structure connected to the delivery catheter into the inferior vena cava. The second inflatable chamber structure can be connected to the first inflatable chamber structure by a conduit that extends through a wall in the aorta and a wall in the inferior vena cava. Once connected, the second inflatable chamber structure can be in fluid communication with the first inflatable chamber structure. In some embodiments, the second inflatable chamber structure can be deployed in the inferior vena cava to axially overlap at least a portion of the renal veins input to the inferior vena cava.

[0113] At 1708, fluid can be pumped into the first fluid vessel and / or the second fluid vessel using the first inflatable chamber structure and / or the second inflatable chamber structure. For example, blood can be drawn from a renal vein into a suction cavity associated with the second inflatable chamber structure during diastole and pumped out of the suction cavity during systole. In some embodiments, blood can be drawn into the suction cavity by inflating the first inflatable chamber structure and deflating the second inflatable chamber structure, and blood can be pumped out of the suction cavity by deflating the first inflatable chamber structure and inflating the second inflatable chamber structure.

[0114] The various embodiments shown in the drawings and described herein include various features. It should be understood that a given embodiment can not include all of the features shown or described in connection with that embodiment, and can include one or more additional features shown or described in connection with one or more other embodiments. That is, features of the illustrated and / or described embodiments of the present disclosure can be combined in any desired manner in embodiments within the scope of the present disclosure.

[0115] Figure 16-5 Figure 17 Additional features and embodiments The above description of embodiments of the present disclosure is not intended to exhaust or limit the present disclosure to the precise forms disclosed. While specific embodiments and examples are described above for illustrative purposes, various equivalent modifications are possible within the scope of the present disclosure, as will be recognized by those skilled in the relevant art. For example, while processes or blocks are presented in a given order, alternative embodiments can perform routines having steps in a different order, or employ systems having blocks in a different order, and some processes or blocks can be deleted, moved, added, subdivided, combined, and / or modified. Each of these processes or blocks can be implemented in a variety of different ways. Also, while processes or blocks are at times shown as being performed serially, these processes or blocks can instead be performed in parallel, or at different times.

[0116] Certain positional terminology is used herein with respect to various disclosed embodiments. Although certain spatially relative terms, such as “outer,” “inner,” “upper,” “lower,” “below,” “above,” “vertical,” “horizontal,” “top,” “bottom,” and similar terms, are used herein to describe a spatial relationship of one device / element or anatomical structure to another device / element or anatomical structure, it is understood that these terms are used herein to describe a position relationship of elements / structures as illustrated in the figures, and are used for convenience of description. In addition to the orientation depicted in the figures, the spatially relative terms are intended to encompass different orientations of the elements / structures in use or operation in addition to the orientations depicted in the figures. For example, an element / structure described as being “above” another element / structure can be positioned below or beside the other element / structure relative to the orientation of the subject patient or element / structure, and vice versa.

[0117] Conditional language used herein, such as, among others, “can,” “could,” “might,” “may,” “e.g.,” and the like, unless specifically stated otherwise, or otherwise understood within the context as used by those of ordinary skill in the art, is intended in its normal sense and is generally intended to convey that certain embodiments include, while other embodiments do not include, certain features, elements and / or steps. Thus, such conditional language is not generally intended to imply that features, elements and / or steps are in any way required for one or more embodiments or that one or more embodiments necessarily include logic for deciding, with or without author input or prompting, whether these features, elements and / or steps are included or are to be performed in any particular embodiment.

[0118] It will be appreciated that certain ordinal terminology, such as “first” or “second,” can be provided for ease of reference and do not necessarily imply a physical feature or order. Thus, as used herein, ordinal terminology used to modify an element such as a structure, component, operation, etc. (e.g., “first,” “second,” “third,” etc.) does not necessarily indicate a priority or order of the element relative to any other element, but rather the element can generally be distinguished from another element having a similar or identical name but using ordinal terminology. Further, as used herein, the indefinite articles “a” and “an” can mean “one or more” rather than “one.” Additionally, an operation performed “based on” a condition or event can also be performed based on one or more other conditions or events that are not explicitly listed. In some contexts, describing an operation or event as “based on” or “based at least in part on” a stated event or condition can be construed as the operation or event being triggered or performed as a result of the stated event or condition, or in response to the stated event or condition.

[0119] With respect to various methods and processes disclosed herein, although processes and / or steps are illustrated and / or described as occurring in a certain order, it should be understood that the ordering could be modified and / or other processes and / or steps could be added and / or removed from the illustrated ordering without departing from the scope of the various inventive aspects. Further, any illustrated and / or described processes and / or steps can be omitted from any given process and / or procedure without departing from the scope of the processes and / or procedures.

[0120] It should be understood that in the foregoing description of the embodiments, various features are sometimes grouped together in a single embodiment, figure, or description of a figure for the purpose of streamlining the disclosure and aiding in the understanding of one or more of the various inventive aspects. However, this method of disclosure should not be interpreted as reflecting an intention that the claim require more features than the claim expressly recites. Moreover, any of the components, features, or steps in any of the embodiments can be applied to (one or more) any other embodiment or used in any other embodiment, alone or in combination with other steps and / or components. Furthermore, no component, feature, step or component, feature, or step combination is essential or indispensable to the practice of the application. Thus, the scope of the application disclosed and sought should not be limited to the above described embodiments but rather be determined with reference to the appended claims along with their full scope of equivalents.

[0121] Unless the context clearly requires otherwise, throughout the description and the claims, the words "comprise," "comprising," "have," "having," "include," "including," and the like are to be construed in an open, inclusive sense, as opposed to an exclusive or exhaustive sense; that is to say, in the sense of "including but not limited to."

[0122] As generally used herein, the word "coupled" means the two or more elements it connects or otherwise associates with each other can be directly or indirectly connected or otherwise associated with each other (e.g., by one or more intermediate elements, components, and / or devices). Also, as used herein, the words "herein," "above," "below," and words of similar effect, shall refer to this application as a whole and not to particular portions of the application unless the context clearly dictates otherwise. Where the context permits, words in the singular or plural number used in this disclosure can also include the plural or singular number, respectively.

[0123] The word “or” in reference to a list of two or more items, that word covers all of the following interpretations of the word: any of the items in the list, all of the items in the list, and any combination of the items in the list. Also, as used herein, the term “and / or” when used between elements in a list of elements (for example, between the last two elements of a list of three elements) means any one or more of the referenced elements. For example, the phrase “A, B, and / or C” means “A,” “B,” “C,” “A and B,” “A and C,” “B and C,” or “A, B, and C.” As used herein, the terms “approximately” and “about” provide a margin of error regarding the corresponding terms and / or items to which they relate. For some industries, the industry-recognized margin of error is less than 1%, while for other industries, the industry-recognized margin of error can be 10% or more. Other example ranges of industry-recognized margins of error range from less than 1% to 50%. Industry-recognized margins of error correspond to, but are not limited to, component values, integrated circuit process variations, temperature variations, rise and fall times, thermal noise, dimensions, signal errors, dropped data packets, temperature, pressure, material composition, and / or performance metrics. Within an industry, the margin of error for a recognized tolerance can be greater than or less than a percentage level (e.g., a dimension tolerance of less than about + / - 1%). Some correlations between items can range from less than a percentage level to a few percentage points of difference. Other correlations between items can range from a few percentage points of difference to orders of magnitude of difference.

[0124] One or more embodiments have been described above with reference to method steps that are illustrated in a particular order. For ease of description, boundaries and sequences of these function building blocks and method steps have been arbitrarily defined herein. Alternative boundaries and sequences can be defined so long as the specified functions and relationships are appropriately performed. Accordingly, any alternative boundaries or sequences are within the scope and spirit of the claims. In addition, boundaries of the function building blocks have been arbitrarily defined for the convenience of the description. Alternative boundaries can be defined so long as the specified functions are appropriately performed. Similarly, the flowchart blocks can have been arbitrarily defined herein to illustrate certain important functions. The flowchart blocks state a purpose of a group of functions, but other functions can be added in between them or otherwise suggest that the order described is not the only order in which the group of functions can be executed.

[0125] Within the scope of use, the flowchart block boundaries and sequence can have been defined in other ways and still perform certain important functions. Accordingly, such alternative definitions of the function building blocks and flowchart blocks, and sequences are within the scope and spirit of the claims. One of ordinary skill in the art will further appreciate that the function building blocks and other illustrative blocks, modules and components herein can be implemented as described herein or through other structure ascompletely or partially combined with a processor that executes appropriate software, other processing unit or control circuitry, a combination of two or more of these, or the like.

[0126] One or more aspects, features, concepts, and / or examples are described herein using one or more embodiments. Physical embodiments of devices, articles, machines, and / or processes can include one or more aspects, features, concepts, examples, etc. described with reference to one or more embodiments discussed herein. Moreover, from figure to figure, embodiments can incorporate the same or similar nomenclature, functions, steps, modules, etc. that can use the same, related, or unrelated reference numerals. Related features, elements, functions, operations, modules, etc. can be the same or similar functions or can be unrelated.

Claims

1. An intervascular fluid pump, comprising: A first expandable chamber structure is configured to be implanted into a first fluid vessel; as well as A second expandable chamber structure is configured to be implanted within a second fluid vessel adjacent to the first fluid vessel, the second expandable chamber structure extending longitudinally and in fluid communication with the first expandable chamber structure. The compression of the first expandable chamber structure causes the expansion of the second expandable chamber structure.

2. The intervascular fluid pump according to claim 1, further comprising: The first pipe structure has an hourglass-shaped profile and a longitudinally extending lumen; as well as A second conduit structure extends longitudinally and includes one or more radially extending holes, the second conduit structure being configured to receive at least a portion of the first conduit structure and be longitudinally aligned with the first conduit structure. The second expandable chamber structure is configured to be disposed between the first pipe structure and the second pipe structure.

3. The intervascular fluid pump according to claim 2, further comprising: A valve structure configured to be longitudinally aligned with the first conduit structure and configured to be disposed between the second expandable chamber structure and the second conduit structure, the valve structure being configured to be radially displaced to block the one or more orifices of the second conduit structure when the second expandable chamber structure expands.

4. The intervascular fluid pump of claim 3, wherein one or more of the second expandable chamber structure and the valve structure have a conical cylindrical shape.

5. The intervascular fluid pump of claim 2, wherein the first conduit structure includes one or more one-way valves disposed at at least one end of the first conduit structure.

6. The intervascular fluid pump according to claim 5, wherein, In the deployed state, the first pipe structure and the second pipe structure are configured to form an intake cavity between the first pipe structure and the second pipe structure, and wherein the second expandable chamber structure is configured to expand radially to push fluid in the intake cavity through the one or more one-way valves.

7. The intervascular fluid pump according to any one of claims 1-6, wherein one or more of the first expandable chamber structure and the second expandable chamber structure comprises a wireframe structure.

8. The intervascular fluid pump according to any one of claims 1-7, further comprising a conduit structure that connects the first expandable chamber structure to the second expandable chamber structure via fluid.

9. A method for increasing diastolic blood pressure, the method comprising: Deploy the first expandable chamber structure in the patient's aorta; as well as A second expandable chamber structure is deployed in the patient's inferior vena cava. The second expandable chamber structure is in fluid communication with the first expandable chamber structure via a conduit structure that extends through the walls of the aorta and the inferior vena cava.

10. The method of claim 9, wherein deploying the second expandable chamber structure comprises deploying the second expandable chamber structure in the inferior vena cava to axially overlap at least a portion of the renal vein into the inferior vena cava.

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